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Pesquisa : G07.265.216.500 [Categoria DeCS]
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[PMID]:29231016
[Au] Autor:Meng HH; Luo B; Siyit T; Ji MM; Chen XP; Shi GF; Tao LY
[Ad] Endereço:Department of Forensic Medicine, School of Forensic Medicine and Laboratory Medicine, Jining Medical University, Jining 272012, China.
[Ti] Título:[Effect of Different Attentional Conditions on ERP Detection of Visual Acuity].
[So] Source:Fa Yi Xue Za Zhi;33(2):125-128, 2017 Apr.
[Is] ISSN:1004-5619
[Cp] País de publicação:China
[La] Idioma:chi
[Ab] Resumo:OBJECTIVES: To study the effect of different attentional conditions on the event-related potential (ERP) components generated by the visual information stimuli related to visual acuity, and provide a theoretical reference for clinical forensic visual objective evaluation. METHODS: With visual acuity optotypes as normal form of visual information stimuli, 15 volunteers as study subjects were supposed to account the visual acuity optotypes under the attentional condition of visual stimuli. Furthermore, the subjects were required to listen to the storytelling carefully under the non-attentional condition of visual stimuli, and after the examination, they needed to answer the story-related questions. All the EEG results of two different attentional conditions from the subjects were recorded by 32 channel ERP system. RESULTS: Under two attentional conditions, P1 and P300 components were evoked by the visual acuity optotypes on supra-threshold and threshold visual acuity levels, while only P1 component were evoked by the visual acuity optotypes on sub-threshold levels. In the ERP waveforms evoked by the visual acuity optotypes on supra-threshold, P1 and P300 amplitudes under attentional condition were larger than that under non-attentional condition. CONCLUSIONS: Attentional conditions can influence the detection of visual acuity. P300 component can be used to distinguish the visual acuity levels with supra-threshold and sub-threshold under non-attentional condition.
[Mh] Termos MeSH primário: Atenção/fisiologia
Potenciais Evocados Visuais
Acuidade Visual
[Mh] Termos MeSH secundário: Eletroencefalografia
Potenciais Evocados
Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171213
[St] Status:MEDLINE
[do] DOI:10.3969/j.issn.1004-5619.2017.02.004


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[PMID]:27771347
[Au] Autor:Rogasch NC; Sullivan C; Thomson RH; Rose NS; Bailey NW; Fitzgerald PB; Farzan F; Hernandez-Pavon JC
[Ad] Endereço:Brain and Mental Health Laboratory, School of Psychological Sciences and Monash Biomedical Imaging, Monash Institute of Cognitive and Clinical Neuroscience, Monash University, Australia. Electronic address: nigel.rogasch@monash.edu.
[Ti] Título:Analysing concurrent transcranial magnetic stimulation and electroencephalographic data: A review and introduction to the open-source TESA software.
[So] Source:Neuroimage;147:934-951, 2017 Feb 15.
[Is] ISSN:1095-9572
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The concurrent use of transcranial magnetic stimulation with electroencephalography (TMS-EEG) is growing in popularity as a method for assessing various cortical properties such as excitability, oscillations and connectivity. However, this combination of methods is technically challenging, resulting in artifacts both during recording and following typical EEG analysis methods, which can distort the underlying neural signal. In this article, we review the causes of artifacts in EEG recordings resulting from TMS, as well as artifacts introduced during analysis (e.g. as the result of filtering over high-frequency, large amplitude artifacts). We then discuss methods for removing artifacts, and ways of designing pipelines to minimise analysis-related artifacts. Finally, we introduce the TMS-EEG signal analyser (TESA), an open-source extension for EEGLAB, which includes functions that are specific for TMS-EEG analysis, such as removing and interpolating the TMS pulse artifact, removing and minimising TMS-evoked muscle activity, and analysing TMS-evoked potentials. The aims of TESA are to provide users with easy access to current TMS-EEG analysis methods and to encourage direct comparisons of these methods and pipelines. It is hoped that providing open-source functions will aid in both improving and standardising analysis across the field of TMS-EEG research.
[Mh] Termos MeSH primário: Artefatos
Encéfalo/fisiologia
Eletroencefalografia/métodos
Potenciais Evocados/fisiologia
Estimulação Magnética Transcraniana/métodos
[Mh] Termos MeSH secundário: Eletroencefalografia/normas
Seres Humanos
Estimulação Magnética Transcraniana/normas
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180306
[Lr] Data última revisão:
180306
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161025
[St] Status:MEDLINE


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[PMID]:29310714
[Au] Autor:Fujiwara K; Yaguchi C; Maekawa M; Kiyota N
[Ad] Endereço:Department of Sports and Health, Kanazawa Gakuin University, 10 Sue-machi, Kanazawa, 920-1392, Japan. fujikatu@kanazawa-gu.ac.jp.
[Ti] Título:Timings of attentional switching to perturbation and postural preparation during transient forward or backward floor translation.
[So] Source:J Physiol Anthropol;37(1):1, 2018 Jan 08.
[Is] ISSN:1880-6805
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Relationships between the timings of attentional switching and postural preparation were investigated using a choice-reaction paradigm with transient floor translation (S2), with the direction indicated by a warning auditory signal (S1). METHODS: Thirteen healthy young adults participated in this study. S2 started 2 s after S1 onset while standing on the platform. The platform moved forward when S1 was a high tone, and backward when S1 was a low tone. In the S1-S2 period, attentional switching was evaluated by P3 component of event-related potential. RESULTS: A shift in the center of pressure in the anteroposterior direction (CoPap) or a continuous increase in postural muscle activation toward S2 was recognized as postural preparation. Changes in postural muscle activation were found just before the CoPap shift. P3 was observed about 250-650 ms after S1. Onset of postural preparation was significantly later (about 200 ms) than latency of P3 (p < 0.001) and correlated strongly with P3 latency (forward: r = 0.81, backward: r = 0.74, p < 0.01). CONCLUSION: Postural preparation for S2 was demonstrated to start after attentional switching from S1 to S2.
[Mh] Termos MeSH primário: Atenção/fisiologia
Equilíbrio Postural/fisiologia
Postura/fisiologia
[Mh] Termos MeSH secundário: Adulto
Eletromiografia
Potenciais Evocados/fisiologia
Feminino
Seres Humanos
Masculino
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180223
[Lr] Data última revisão:
180223
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180110
[St] Status:MEDLINE
[do] DOI:10.1186/s40101-017-0162-6


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[PMID]:27771287
[Au] Autor:Casula EP; Stampanoni Bassi M; Pellicciari MC; Ponzo V; Veniero D; Peppe A; Brusa L; Stanzione P; Caltagirone C; Stefani A; Koch G
[Ad] Endereço:Non-Invasive Brain Stimulation Unit, Neurologia Clinica e Comportamentale, Fondazione Santa Lucia IRCCS, Rome, Italy.
[Ti] Título:Subthalamic stimulation and levodopa modulate cortical reactivity in Parkinson's patients.
[So] Source:Parkinsonism Relat Disord;34:31-37, 2017 Jan.
[Is] ISSN:1873-5126
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The effects of deep brain stimulation of the subthalamic nucleus (DBS-STN) and L-dopa (LD) on cortical activity in Parkinson's disease (PD) are poorly understood. OBJECTIVES: By combining transcranial magnetic stimulation (TMS) and electroencephalography (EEG) we explored the effects of STN-DBS, either alone or in combination with L-Dopa (LD), on TMS-evoked cortical activity in a sample of implanted PD patients. METHODS: PD patients were tested in three clinical conditions: i) LD therapy with STN-DBS turned on (ON/ON condition); ii) without LD therapy with STN-DBS turned on (OFF/ON condition); iii) without LD therapy with STN-DBS turned off (OFF/OFF condition). TMS pulses were delivered over left M1 while simultaneously acquiring EEG. Eight age-matched healthy volunteers (HC) were tested as a control group. RESULTS: STN-DBS enhanced early global TMS-evoked activity (∼45-80ms) and high-alpha TMS-evoked oscillations (11-13 Hz) as compared to OFF/OFF condition, independently from concomitant LD therapy. LD intake (ON/ON condition) produced a further increase of late TMS-evoked activity (∼80-130ms) and beta TMS-evoked oscillations (13-30 Hz), as compared to OFF/OFF and OFF/ON conditions, that normalized reactivity as compared to HC range of values. CONCLUSIONS: Our data reveal that bilateral STN-DBS and LD therapy induce a modulation of specific cortical components and specific ranges of frequency. These findings demonstrate that STN-DBS and LD therapy may have synergistic effects on motor cortical activity.
[Mh] Termos MeSH primário: Córtex Cerebral/efeitos dos fármacos
Estimulação Encefálica Profunda
Levodopa/farmacologia
Levodopa/uso terapêutico
Doença de Parkinson/terapia
Núcleo Subtalâmico/fisiologia
[Mh] Termos MeSH secundário: Idoso
Antiparkinsonianos/farmacologia
Antiparkinsonianos/uso terapêutico
Mapeamento Encefálico
Estudos de Casos e Controles
Córtex Cerebral/fisiopatologia
Eletroencefalografia
Potenciais Evocados/efeitos dos fármacos
Potenciais Evocados/fisiologia
Feminino
Seres Humanos
Masculino
Meia-Idade
Doença de Parkinson/tratamento farmacológico
Doença de Parkinson/patologia
Índice de Gravidade de Doença
Análise Espectral
Estimulação Magnética Transcraniana
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antiparkinson Agents); 46627O600J (Levodopa)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180215
[Lr] Data última revisão:
180215
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161025
[St] Status:MEDLINE


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[PMID]:28457836
[Au] Autor:Kasinadhuni AK; Indahlastari A; Chauhan M; Schär M; Mareci TH; Sadleir RJ
[Ad] Endereço:J. Crayton Pruitt Department of Biomedical Engineering, University of Florida, Gainesville FL, USA.
[Ti] Título:Imaging of current flow in the human head during transcranial electrical therapy.
[So] Source:Brain Stimul;10(4):764-772, 2017 Jul - Aug.
[Is] ISSN:1876-4754
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: It has been assumed that effects caused by tDCS or tACS neuromodulation are due to electric current flow within brain structures. However, to date, direct current density distributions in the brains of human subjects have not been measured. Instead computational models of tDCS or tACS have been used to predict electric current and field distributions for dosimetry and mechanism analysis purposes. OBJECTIVE/HYPOTHESIS: We present the first in vivo images of electric current density distributions within the brain in four subjects undergoing transcranial electrical stimulation. METHODS: Magnetic resonance electrical impedance tomography (MREIT) techniques encode current flow in phase images. In four human subjects, we used MREIT to measure magnetic flux density distributions caused by tACS currents, and then calculated current density distributions from these data. Computational models of magnetic flux and current distribution, constructed using contemporaneously collected T -weighted structural MRI images, were co-registered to compare predicted and experimental results. RESULTS: We found consistency between experimental and simulated magnetic flux and current density distributions using transtemporal (T7-T8) and anterior-posterior (Fpz-Oz) electrode montages, and also differences that may indicate a need to improve models to better interpret experimental results. While human subject data agreed with computational model predictions in overall scale, differences may result from factors such as effective electrode surface area and conductivities assumed in models. CONCLUSIONS: We believe this method may be useful in improving reproducibility, assessing safety, and ultimately aiding understanding of mechanisms of action in electrical and magnetic neuromodulation modalities.
[Mh] Termos MeSH primário: Encéfalo/fisiologia
Potenciais Evocados
Imagem por Ressonância Magnética/métodos
Modelos Neurológicos
Estimulação Transcraniana por Corrente Contínua/métodos
[Mh] Termos MeSH secundário: Encéfalo/diagnóstico por imagem
Impedância Elétrica
Eletrodos
Análise de Elementos Finitos
Seres Humanos
Imagem por Ressonância Magnética/normas
Masculino
Reprodutibilidade dos Testes
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180205
[Lr] Data última revisão:
180205
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170502
[St] Status:MEDLINE


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[PMID]:29173744
[Au] Autor:Buzzell GA; Troller-Renfree SV; Barker TV; Bowman LC; Chronis-Tuscano A; Henderson HA; Kagan J; Pine DS; Fox NA
[Ad] Endereço:University of Maryland-College Park. Electronic address: gbuzzell@umd.edu.
[Ti] Título:A Neurobehavioral Mechanism Linking Behaviorally Inhibited Temperament and Later Adolescent Social Anxiety.
[So] Source:J Am Acad Child Adolesc Psychiatry;56(12):1097-1105, 2017 Dec.
[Is] ISSN:1527-5418
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: Behavioral inhibition (BI) is a temperament identified in early childhood that is a risk factor for later social anxiety. However, mechanisms underlying the development of social anxiety remain unclear. To better understand the emergence of social anxiety, longitudinal studies investigating changes at behavioral neural levels are needed. METHOD: BI was assessed in the laboratory at 2 and 3 years of age (N = 268). Children returned at 12 years, and an electroencephalogram was recorded while children performed a flanker task under 2 conditions: once while believing they were being observed by peers and once while not being observed. This methodology isolated changes in error monitoring (error-related negativity) and behavior (post-error reaction time slowing) as a function of social context. At 12 years, current social anxiety symptoms and lifetime diagnoses of social anxiety were obtained. RESULTS: Childhood BI prospectively predicted social-specific error-related negativity increases and social anxiety symptoms in adolescence; these symptoms directly related to clinical diagnoses. Serial mediation analysis showed that social error-related negativity changes explained relations between BI and social anxiety symptoms (n = 107) and diagnosis (n = 92), but only insofar as social context also led to increased post-error reaction time slowing (a measure of error preoccupation); this model was not significantly related to generalized anxiety. CONCLUSION: Results extend prior work on socially induced changes in error monitoring and error preoccupation. These measures could index a neurobehavioral mechanism linking BI to adolescent social anxiety symptoms and diagnosis. This mechanism could relate more strongly to social than to generalized anxiety in the peri-adolescent period.
[Mh] Termos MeSH primário: Comportamento do Adolescente/fisiologia
Transtornos de Ansiedade/etiologia
Ansiedade/etiologia
Comportamento Infantil/fisiologia
Inibição (Psicologia)
Temperamento/fisiologia
[Mh] Termos MeSH secundário: Adolescente
Comportamento do Adolescente/psicologia
Ansiedade/diagnóstico
Ansiedade/fisiopatologia
Ansiedade/psicologia
Transtornos de Ansiedade/diagnóstico
Transtornos de Ansiedade/fisiopatologia
Transtornos de Ansiedade/psicologia
Criança
Comportamento Infantil/psicologia
Eletroencefalografia
Potenciais Evocados
Feminino
Seres Humanos
Estudos Longitudinais
Masculino
Estudos Prospectivos
Escalas de Graduação Psiquiátrica
Fatores de Risco
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180202
[Lr] Data última revisão:
180202
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171128
[St] Status:MEDLINE


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[PMID]:28460282
[Au] Autor:Ertekin E; Üçok A; Keskin-Ergen Y; Devrim-Üçok M
[Ad] Endereço:Department of Psychiatry, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
[Ti] Título:Deficits in Go and NoGo P3 potentials in patients with schizophrenia.
[So] Source:Psychiatry Res;254:126-132, 2017 Aug.
[Is] ISSN:1872-7123
[Cp] País de publicação:Ireland
[La] Idioma:eng
[Ab] Resumo:Cognitive control processes elicited during a cued continuous performance test were evaluated using event-related potentials in 46 patients who were within the first 5 years of diagnosis of schizophrenia, and 29 healthy controls. Patients had longer reaction times, lower hit rates, and higher false alarm rates compared with controls. Patients had an overall P3 amplitude reduction that was more prominent on NoGo compared with Go trials. This greater P3 reduction on NoGo trials was present in central and parietal regions, but was absent in the frontal region, where the P3 reduction was comparable on NoGo and Go trials. Our findings suggest that the neural activity contributing to Go and NoGo P3s are both deteriorated in schizophrenia, but those contributing to central and parietal NoGo P3s are the most severely affected ones. We conclude that the cognitive control processes engaged during execution, and particularly during inhibition of a prepared motor response were disturbed in the early course of schizophrenia. Our findings might be related to our sample being in relatively early stages of schizophrenia and/or related to the use of atypical antipsychotics by most of our patients.
[Mh] Termos MeSH primário: Potenciais Evocados/fisiologia
Tempo de Reação/fisiologia
Esquizofrenia/diagnóstico
Esquizofrenia/fisiopatologia
Psicologia do Esquizofrênico
[Mh] Termos MeSH secundário: Adolescente
Adulto
Sinais (Psicologia)
Eletroencefalografia/métodos
Feminino
Lobo Frontal/fisiopatologia
Seres Humanos
Masculino
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180131
[Lr] Data última revisão:
180131
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170502
[St] Status:MEDLINE


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[PMID]:28461682
[Au] Autor:Hull C
[Ad] Endereço:Department of Neurobiology, Duke University, Durham, North Carolina 27710 Hull@neuro.duke.edu.
[Ti] Título:Cellular and Synaptic Properties of Local Inhibitory Circuits.
[So] Source:Cold Spring Harb Protoc;2017(5):pdb.top095281, 2017 May 01.
[Is] ISSN:1559-6095
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Inhibitory interneurons play a key role in sculpting the information processed by neural circuits. Despite the wide range of physiologically and morphologically distinct types of interneurons that have been identified, common principles have emerged that have shed light on how synaptic inhibition operates, both mechanistically and functionally, across cell types and circuits. This introduction summarizes how electrophysiological approaches have been used to illuminate these key principles, including basic interneuron circuit motifs, the functional properties of inhibitory synapses, and the main roles for synaptic inhibition in regulating neural circuit function. It also highlights how some key electrophysiological methods and experiments have advanced our understanding of inhibitory synapse function.
[Mh] Termos MeSH primário: Fenômenos Eletrofisiológicos/fisiologia
Neurônios/fisiologia
Sinapses/fisiologia
[Mh] Termos MeSH secundário: Animais
Excitabilidade Cortical/fisiologia
Potenciais Evocados
Interneurônios/fisiologia
Potenciais da Membrana/fisiologia
Neurônios Motores/fisiologia
Neurotransmissores/fisiologia
Transmissão Sináptica/fisiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Neurotransmitter Agents)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180129
[Lr] Data última revisão:
180129
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170503
[St] Status:MEDLINE
[do] DOI:10.1101/pdb.top095281


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[PMID]:28461661
[Au] Autor:Hull C
[Ad] Endereço:Department of Neurobiology, Duke University, Durham, North Carolina 27710 Hull@neuro.duke.edu.
[Ti] Título:Measuring Feedforward Inhibition and Its Impact on Local Circuit Function.
[So] Source:Cold Spring Harb Protoc;2017(5):pdb.prot095828, 2017 May 01.
[Is] ISSN:1559-6095
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:This protocol describes a series of approaches to measure feedforward inhibition in acute brain slices from the cerebellar cortex. Using whole-cell voltage and current clamp recordings from Purkinje cells in conjunction with electrical stimulation of the parallel fibers, these methods demonstrate how to measure the relationship between excitation and inhibition in a feedforward circuit. This protocol also describes how to measure the impact of feedforward inhibition on Purkinje cell excitability, with an emphasis on spike timing.
[Mh] Termos MeSH primário: Córtex Cerebelar/fisiologia
Fenômenos Eletrofisiológicos/fisiologia
[Mh] Termos MeSH secundário: Animais
Estimulação Elétrica
Potenciais Evocados/fisiologia
Potenciais da Membrana/fisiologia
Técnicas de Patch-Clamp
Células de Purkinje/fisiologia
Sinapses/fisiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180129
[Lr] Data última revisão:
180129
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170503
[St] Status:MEDLINE
[do] DOI:10.1101/pdb.prot095828


  10 / 49118 MEDLINE  
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[PMID]:27773679
[Au] Autor:Herweg A; Gutzeit J; Kleih S; Kübler A
[Ad] Endereço:Institute of Psychology, University of Würzburg, Marcusstr 9-11, 97070 Würzburg, Germany.
[Ti] Título:Wheelchair control by elderly participants in a virtual environment with a brain-computer interface (BCI) and tactile stimulation.
[So] Source:Biol Psychol;121(Pt A):117-124, 2016 12.
[Is] ISSN:1873-6246
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Tactile event-related potential (ERP) are rarely used as input signal to control brain-computer-interfaces (BCI) due to their low accuracy and speed (information transfer rate, ITR). Age-related loss of tactile sensibility might further decrease their viability for the target population of BCI. In this study we investigated whether training improves tactile ERP-BCI performance within a virtual wheelchair navigation task. Elderly subjects participated in 5 sessions and tactors were placed at legs, abdomen and back. Mean accuracy and ITR increased from 88.43%/4.5bitsmin in the 1st to 92.56%/4.98bitsmin in the last session. The mean P300 amplitude increased from 5.46µV to 9.22µV. In an optional task participants achieved an accuracy of 95,56% and a mean ITR of 20,73bitsmin which is the highest ever achieved with tactile stimulation. Our sample of elderly people further contributed to the external validity of our results.
[Mh] Termos MeSH primário: Interfaces Cérebro-Computador/psicologia
Potenciais Evocados/fisiologia
Tato/fisiologia
Interface Usuário-Computador
Cadeiras de Rodas
[Mh] Termos MeSH secundário: Idoso
Meio Ambiente
Feminino
Voluntários Saudáveis
Seres Humanos
Masculino
Meia-Idade
Estimulação Física/métodos
Análise e Desempenho de Tarefas
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1709
[Cu] Atualização por classe:180125
[Lr] Data última revisão:
180125
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161107
[St] Status:MEDLINE



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