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[PMID]:28458114
[Au] Autor:Liao H; Duan G; Liu P; Liu Y; Pang Y; Liu H; Tang L; Tao J; Wen D; Li S; Liang L; Deng D
[Ad] Endereço:Department of Radiology, First Affiliated Hospital, Guangxi University of Chinese Medicine, Nanning, Guangxi 530023, China.
[Ti] Título:Altered fractional amplitude of low frequency fluctuation in premenstrual syndrome: A resting state fMRI study.
[So] Source:J Affect Disord;218:41-48, 2017 Aug 15.
[Is] ISSN:1573-2517
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Premenstrual syndrome (PMS) is becoming highly prevalent among female and is characterized by emotional, physical and behavior symptoms. Previous evidence suggested functional dysregulation of female brain was expected to be involved in the etiology of PMS. The aim of present study was to evaluate the alterations of spontaneous brain activity in PMS patients based on functional magnetic resonance imaging (fMRI). METHODS: 20 PMS patients and 21 healthy controls underwent resting-state fMRI scanning during luteal phase. All participants were asked to complete a prospective daily record of severity of problems (DRSP) questionnaire. RESULTS: Compared with healthy controls, the results showed that PMS patients had increased fALFF in bilateral precuneus, left hippocampus and left inferior temporal cortex, and decreased fALFF in bilateral anterior cingulate cortex (ACC) and cerebellum at luteal phase. Moreover, the DRSP scores of PMS patients were negatively correlated with the mean fALFF in ACC and positively correlated with the fALFF in precuneus. LIMITATIONS: (1) the study did not investigate whether or not abnormal brain activity differences between groups in mid-follicular phase, and within-group changes. between phases.(2) it was relatively limited sample size and the participants were young; (3) fALFF could not provide us with more holistic information of brain network;(4) the comparisons of PMS and premenstrual dysphoric disorder (PMDD) were not involved in the study. CONCLUSIONS: The present study shows abnormal spontaneous brain activity in PMS patients revealed by fALFF, which could provide neuroimaging evidence to further improve our understanding of the underlying neural mechanism of PMS.
[Mh] Termos MeSH primário: Encéfalo/fisiopatologia
Imagem por Ressonância Magnética/métodos
Síndrome Pré-Menstrual/fisiopatologia
[Mh] Termos MeSH secundário: Adulto
Mapeamento Encefálico/métodos
Feminino
Fase Folicular
Giro do Cíngulo/fisiopatologia
Seres Humanos
Fase Luteal
Neuroimagem
Lobo Parietal/fisiopatologia
Transtorno Disfórico Pré-Menstrual/fisiopatologia
Estudos Prospectivos
Lobo Temporal
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180115
[Lr] Data última revisão:
180115
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170502
[St] Status:MEDLINE


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[PMID]:27773641
[Au] Autor:Samanci C; Alis D; Ustabasioglu FE; Ozmen E; Ucar AK; Aslan M; Habibi HA; Bakan S; Ozcabi B; Evliyaoglu SO; Adaletli I
[Ad] Endereço:Department of radiology, Cerrahpasa faculty of medicine, Istanbul university, KMPasa, Cerrahpasa Medical, Kocamustapasa street, 34098 Fatih/Istanbul, Turkey. Electronic address: cesursamanci@gmail.com.
[Ti] Título:Apparent diffusion coefficient measurement of ovarian stroma: A potential tool for the diagnosis of polycystic ovary syndrome.
[So] Source:Diagn Interv Imaging;98(1):57-61, 2017 Jan.
[Is] ISSN:2211-5684
[Cp] País de publicação:France
[La] Idioma:eng
[Ab] Resumo:PURPOSE: The purpose of this study was to assess the diagnostic value of measuring the apparent diffusion coefficient (ADC) of ovarian stroma in polycystic ovary syndrome (PCOS). MATERIALS AND METHODS: This study was approved by the institutional review board and informed consent was obtained from each women. A total of 17 women (mean age, 22.2 years±5.1 [SD]; range, 16-33 years) with a diagnosis of PCOS according to the Androgen Excess and PCOS Society criteria and 18 healthy women (mean age, 22.8 years±5.2 [SD]; range, 16-31 years) who served as a control group were included in this prospective study. ADC values of the ovarian stroma during the early follicular phase were calculated by two observers in the two groups. Comparisons were performed using the Student t-test. RESULTS: The mean ADC value in woman with PCOS (1.29±0.27×10 mm /s; range: 0.59×10 - 1.88×10 mm /s) was significantly lower than that in the control group (1.48±0.17×10 mm /s; range: 1.12×10 - 1.86×10 mm /s) (P<0.001). The ADC cutoff value for the determination of PCOS with maximum accuracy was 1.38×10 mm /s (AUC: 0.720; 95% CI: 0.597, 0.843), yielding 78% sensitivity and 62.9% specificity. CONCLUSION: ADC values of ovarian stroma are lower in patients with PCOS than in control subjects. ADC measurement of ovarian stroma in women with PCOS might help improve the diagnosis of PCOS.
[Mh] Termos MeSH primário: Imagem de Difusão por Ressonância Magnética
Ovário/diagnóstico por imagem
Síndrome do Ovário Policístico/diagnóstico
[Mh] Termos MeSH secundário: Adolescente
Adulto
Estudos de Casos e Controles
Feminino
Fase Folicular
Seres Humanos
Estudos Prospectivos
Sensibilidade e Especificidade
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180109
[Lr] Data última revisão:
180109
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161025
[St] Status:MEDLINE


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[PMID]:28466535
[Au] Autor:Phoophitphong D; Srisuwatanasagul S; Tummaruk P
[Ad] Endereço:Department of Obstetrics, Gynaecology and Reproduction, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, 10330, Thailand.
[Ti] Título:Leptin Immunohistochemical Staining in the Porcine Ovary.
[So] Source:Anat Histol Embryol;46(4):334-341, 2017 Aug.
[Is] ISSN:1439-0264
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:This study aimed to investigate leptin immuno-staining of the porcine ovary in different reproductive stages. Ovaries from 21 gilts were collected from slaughterhouses. The ovarian tissue sections were incubated with a polyclonal anti-leptin as a primary antibody. The immuno-staining in ovarian tissue compartments was calculated using imaging software. Leptin immuno-staining was found in primordial, primary, preantral and antral follicles. Leptin immuno-staining was expressed in the oocyte and granulosa and theca interna layers in both preantral and antral follicles. In the corpora lutea, leptin immuno-staining was found in the cytoplasm of the luteal cells. The leptin immuno-staining in the granulosa cell layer of preantral follicles did not differ compared to antral follicles (90.7 and 91.3%, respectively, P > 0.05). However, the leptin immuno-staining in the theca interna layer of preantral follicles was lower than antral follicles (49.4 and 74.3%, respectively, P < 0.001). There was no difference in leptin immuno-staining in the granulosa cell layer between follicular and luteal phases (92.4 and 89.7%, respectively, P > 0.05). However, the leptin immuno-staining in the theca interna layer of follicular phase was greater than that in the luteal phase (72.7 and 51.0%, respectively, P < 0.001). These findings indicated that leptin exists in different compartments of the porcine ovary, including the oocyte, granulosa cells, theca interna cells, corpus luteum, blood vessel and smooth muscles. Therefore, this morphological study confirmed a close relationship between leptin and ovarian function in the pig.
[Mh] Termos MeSH primário: Leptina/análise
Ovário/química
Suínos/metabolismo
[Mh] Termos MeSH secundário: Proteínas Angiogênicas
Animais
Peso Corporal/fisiologia
Corpo Lúteo/química
Feminino
Fase Folicular
Células da Granulosa/química
Processamento de Imagem Assistida por Computador
Imuno-Histoquímica/veterinária
Fase Luteal
Oócitos/química
Folículo Ovariano/anatomia & histologia
Folículo Ovariano/química
Ovário/metabolismo
Suínos/anatomia & histologia
Células Tecais/química
Ganho de Peso/fisiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (AGGF1 protein, human); 0 (Angiogenic Proteins); 0 (Leptin)
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171229
[Lr] Data última revisão:
171229
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170504
[St] Status:MEDLINE
[do] DOI:10.1111/ahe.12274


  4 / 3698 MEDLINE  
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[PMID]:28911135
[Au] Autor:Arnoni-Bauer Y; Bick A; Raz N; Imbar T; Amos S; Agmon O; Marko L; Levin N; Weiss R
[Ad] Endereço:Department of Human Metabolism and Nutrition, Braun School of Public Health, Hebrew University, Jerusalem 91120, Israel.
[Ti] Título:Is It Me or My Hormones? Neuroendocrine Activation Profiles to Visual Food Stimuli Across the Menstrual Cycle.
[So] Source:J Clin Endocrinol Metab;102(9):3406-3414, 2017 Sep 01.
[Is] ISSN:1945-7197
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Context: Homeostatic energy balance is controlled via the hypothalamus, whereas regions controlling reward and cognitive decision-making are critical for hedonic eating. Eating varies across the menstrual cycle peaking at the midluteal phase. Objective: To test responses of females with regular cycles during midfollicular and midluteal phase and of users of monophasic oral contraception pills (OCPs) to visual food cues. Design: Participants performed a functional magnetic resonance imaging while exposed to visual food cues in four time points: fasting and fed conditions in midfollicular and midluteal phases. Patients: Twenty females with regular cycles and 12 on monophasic OCP, aged 18 to 35 years. Main Outcome Measures: Activity in homeostatic (hypothalamus), reward (amygdala, putamen and insula), frontal (anterior cingulate cortex, dorsolateral prefrontal cortex), and visual regions (calcarine and lateral occipital cortex). Setting: Tertiary hospital. Results: In females with regular cycles, brain regions associated with homeostasis but also the reward system, executive frontal areas, and afferent visual areas were activated to a greater degree during the luteal compared with the follicular phase. Within the visual areas, a dual effect of hormonal and prandial state was seen. In females on monophasic OCPs, characterized by a permanently elevated progesterone concentration, activity reminiscent of the luteal phase was found. Androgen, cortisol, testosterone, and insulin levels were significantly correlated with reward and visual region activation. Conclusions: Hormonal mechanisms affect the responses of women's homeostatic, emotional, and attentional brain regions to food cues. The relation of these findings to eating behavior throughout the cycle needs further investigation.
[Mh] Termos MeSH primário: Córtex Cerebral/diagnóstico por imagem
Comportamento Alimentar/fisiologia
Imagem por Ressonância Magnética/métodos
Ciclo Menstrual/fisiologia
Sistemas Neurossecretores/fisiologia
Estimulação Luminosa
[Mh] Termos MeSH secundário: Adolescente
Adulto
Tonsila do Cerebelo/fisiologia
Córtex Cerebral/fisiologia
Sinais (Psicologia)
Comportamento Alimentar/psicologia
Feminino
Fase Folicular/fisiologia
Seres Humanos
Hipotálamo/fisiologia
Fase Luteal/fisiologia
Ciclo Menstrual/psicologia
Amostragem
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171012
[Lr] Data última revisão:
171012
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170916
[St] Status:MEDLINE
[do] DOI:10.1210/jc.2016-3921


  5 / 3698 MEDLINE  
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[PMID]:28285572
[Au] Autor:Kim JJ; Kang JH; Lee KW; Kim KH; Song T
[Ad] Endereço:a Department of Obstetrics and Gynecology , Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine , Seoul , Republic of Korea.
[Ti] Título:Optimal timing for performing hysterectomy according to different phase of menstrual cycle: Which is best?
[So] Source:J Obstet Gynaecol;37(4):498-502, 2017 May.
[Is] ISSN:1364-6893
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The aim of this study was to determine whether the different phases of the menstrual cycle could affect operative bleeding in women undergoing laparoscopic hysterectomy. This was a retrospective comparative study. Based on the adjusted day of menstrual cycle, 212 women who underwent laparoscopic hysterectomy were classified into three groups: the follicular phase (n = 51), luteal phase group (n = 125), and menstruation group (n = 36). The primary outcome measure was the operative bleeding. There was no difference in the baseline characteristics of the patients belonging to the three groups. For the groups, there were no significant differences in operative bleeding (p = .469) and change in haemoglobin (p = .330), including operative time, length of hospital stay and complications. The menstrual cycle did not affect the operative bleeding and other parameters. Therefore, no phase of the menstrual cycle could be considered as an optimal timing for performing laparoscopic hysterectomy with minimal operative bleeding. Impact statement What is already known on this subject: the menstrual cycle results in periodic changes in haemostasis and blood flow in the reproductive organs. What the results of this study add: the menstrual cycle did not affect the operative bleeding and other operative parameters during laparoscopic hysterectomy. What the implications are of these findings for clinical practice and/or further research: no phase of the menstrual cycle could be considered as an optimal timing for performing laparoscopic hysterectomy with minimal operative bleeding.
[Mh] Termos MeSH primário: Perda Sanguínea Cirúrgica
Fase Folicular
Histerectomia/métodos
Fase Luteal
Menstruação
Hemorragia Pós-Operatória/prevenção & controle
Fatores de Tempo
[Mh] Termos MeSH secundário: Feminino
Seres Humanos
Histerectomia/efeitos adversos
Laparoscopia
Tempo de Internação
Meia-Idade
Duração da Cirurgia
Estudos Retrospectivos
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170929
[Lr] Data última revisão:
170929
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170314
[St] Status:MEDLINE
[do] DOI:10.1080/01443615.2016.1269731


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[PMID]:28255966
[Au] Autor:Okamoto T; Kobayashi R; Sakamaki-Sunaga M
[Ad] Endereço:Department of Exercise Physiology, Nippon Sport Science University, Tokyo, Japan.
[Ti] Título:Effect of Resistance Exercise on Arterial Stiffness during the Follicular and Luteal Phases of the Menstrual Cycle.
[So] Source:Int J Sports Med;38(5):347-352, 2017 May.
[Is] ISSN:1439-3964
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:Acute high-intensity resistance exercise increases arterial stiffness. Changes in blood concentrations of estrogen and progesterone associated with the menstrual cycle affect the degree of arterial stiffness. Therefore, high-intensity resistance exercise may affect arterial stiffness differently depending on the phase of the menstrual cycle. The purpose of this study was to investigate the effects of different phases of the menstrual cycle on arterial stiffness after one session of resistance exercise. The participants were 9 eumenorrheic females (21.3±0.8 years). All participants performed 5 sets of 5 repetitions using 80% of the one repetition maximum (1RM) bench press and 5 sets of 10 repetitions using 70% of the 1RM biceps curl during both the follicular and luteal phases. Brachial-ankle pulse wave velocity (baPWV), blood pressure, and heart rate were measured before (baseline) and at 30 and 60 min after completing the resistance exercises. During the follicular phase, baPWV was significantly increased at 30 and 60 min after the resistance exercise compared with baseline (P<0.05), whereas during the luteal phase, no significant differences were observed after the resistance exercise. These results suggest that high-intensity resistance exercise affects arterial stiffness differently depending on the phase of the menstrual cycle.
[Mh] Termos MeSH primário: Fase Folicular/fisiologia
Fase Luteal/fisiologia
Treinamento de Resistência
Rigidez Vascular/fisiologia
[Mh] Termos MeSH secundário: Pressão Sanguínea/fisiologia
Artéria Braquial/fisiologia
Estrogênios/sangue
Feminino
Frequência Cardíaca/fisiologia
Seres Humanos
Progesterona/sangue
Análise de Onda de Pulso
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Estrogens); 4G7DS2Q64Y (Progesterone)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170911
[Lr] Data última revisão:
170911
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170304
[St] Status:MEDLINE
[do] DOI:10.1055/s-0043-101377


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[PMID]:28163019
[Au] Autor:Sirotkin AV; Florkovicová Konicková I; Schaeffer HJ; Laurincik J; Harrath AH
[Ad] Endereço:Dept. Zoology and Anthropology, Constantine the Philosopher University, 949 74 Nitra, Slovakia; Dept. Genetics and Reproduction, Research Institute of Animal Production, 949 59 Luzianky, Slovakia. Electronic address: asirotkin@ukf.sk.
[Ti] Título:Interrelationships between ovarian follicles grown in culture and possible mediators.
[So] Source:Reprod Biol;17(1):97-104, 2017 Mar.
[Is] ISSN:2300-732X
[Cp] País de publicação:Poland
[La] Idioma:eng
[Ab] Resumo:Dominance or cooperation between ovarian follicles can determine the number of ovulations and fecundity, but interrelationships between follicles in mono- and poly-ovulatory species and their mechanisms are poorly understood. The goals of this work were to determine the existence and compare the character of mutual influence of cultured ovarian follicles from a mono-ovulatory species (cow) with established follicular dominance with those from a poly-ovulatory species (pig), in which interrelationship between follicles remain unknown, and to examine the role of ovarian cell proliferation, the insulin-like growth factor I (IGF-I)- oxytocin (OT) system, and steroid hormones in mediating interrelationships among ovarian follicles. Bovine and porcine ovarian follicles were isolated and cultured alone and in pairs, and the percentage of growing follicles was calculated. Porcine follicles were cultured alone and in pairs after addition of exogenous OT and IGF-I (100ngmL ) or inactivation of endogenous OT and IGF-I by antisera against these hormones (1%). Proliferation of porcine follicular cells was assessed by SDS PAGE-Western immunoblotting, the release of IGF-I, progesterone, androstenedione and estradiol by cultured porcine ovarian follicles was analyzed by RIA/EIA. Overall, our observations suggest (1) competition/dominance (mutual suppression of growth) in bovine ovarian follicles, (2) cooperation (mutual support of growth) in porcine ovarian follicles, (3) that this mutual growth of porcine ovarian follicles was caused by the promotion of cell proliferation, (4) that this mechanism was probably not involved in bovine follicular dominance, (5) that communication between both porcine and bovine follicles affects their secretory activity, and (6) that both follicular dominance in cows and cooperation of follicles in pigs can be mediated by either down- or up-regulation of the IGF-I-OT system, which in turn affects follicular steroidogenesis and promotes follicular cell proliferation and follicular growth.
[Mh] Termos MeSH primário: Fator de Crescimento Insulin-Like I/metabolismo
Folículo Ovariano/metabolismo
Ocitocina/metabolismo
[Mh] Termos MeSH secundário: Matadouros
Androstenodiona/metabolismo
Androstenodiona/secreção
Animais
Animais Endogâmicos
Bovinos
Proliferação Celular
Estradiol/metabolismo
Estradiol/secreção
Feminino
Fase Folicular
Soros Imunes/farmacologia
Fator de Crescimento Insulin-Like I/antagonistas & inibidores
Fator de Crescimento Insulin-Like I/genética
Fator de Crescimento Insulin-Like I/secreção
Oogênese
Folículo Ovariano/efeitos dos fármacos
Folículo Ovariano/crescimento & desenvolvimento
Folículo Ovariano/secreção
Ocitocina/antagonistas & inibidores
Progesterona/metabolismo
Progesterona/secreção
Proteínas Recombinantes
Eslováquia
Especificidade da Espécie
Sus scrofa
Técnicas de Cultura de Tecidos
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Immune Sera); 0 (Recombinant Proteins); 409J2J96VR (Androstenedione); 4G7DS2Q64Y (Progesterone); 4TI98Z838E (Estradiol); 50-56-6 (Oxytocin); 67763-96-6 (Insulin-Like Growth Factor I)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170719
[Lr] Data última revisão:
170719
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170207
[St] Status:MEDLINE


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[PMID]:28162937
[Au] Autor:Lawrenz B; Fatemi HM
[Ad] Endereço:IVI Middle-East, Royal Marina Village, Villa B22-23, Abu Dhabi, United Arab Emirates; Women's University Hospital Tuebingen, Calwerstr. 7, 72076 Tuebingen, Germany. Electronic address: barbara.lawrenz@ivivf.com.
[Ti] Título:Effect of progesterone elevation in follicular phase of IVF-cycles on the endometrial receptivity.
[So] Source:Reprod Biomed Online;34(4):422-428, 2017 Apr.
[Is] ISSN:1472-6491
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:The premature rise of progesterone during the late follicular phase in stimulated IVF cycles is a frequent event, and emerging evidence shows that premature progesterone rise does negatively affect the outcome of assisted reproductive techniques. The effect of elevated peripheral progesterone levels in the late follicular phase seems to be on the endometrium and the window of implantation, which may lead to asynchrony between the endometrium and the developing embryo. In stimulated cycles, endometrial maturation is advanced on the day of oocyte retrieval, and patients with a progesterone level above 1.5 ng/ml on the day of final oocyte maturation have different endometrial gene expression profiles. This progesterone level seems to represent the critical threshold, at which a negative effect on the ongoing pregnancy rate in fresh IVF cycles can be observed. Moreover, no association exists between progesterone elevation in the fresh cycle, and the probability of pregnancy after transfer of frozen-thawed embryos, originating from that cycle. The causes of premature progesterone elevation during ovarian stimulation are still unclear; however, recent studies point towards enhanced FSH-stimulation as a cause for progesterone elevation.
[Mh] Termos MeSH primário: Implantação do Embrião
Endométrio/fisiologia
Fertilização In Vitro
Fase Folicular/sangue
Progesterona/sangue
[Mh] Termos MeSH secundário: Adulto
Transferência Embrionária
Endométrio/metabolismo
Feminino
Seres Humanos
Indução da Ovulação/efeitos adversos
Gravidez
Taxa de Gravidez
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
4G7DS2Q64Y (Progesterone)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171009
[Lr] Data última revisão:
171009
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170207
[St] Status:MEDLINE


  9 / 3698 MEDLINE  
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[PMID]:28152471
[Au] Autor:Slyepchenko A; Lokuge S; Nicholls B; Steiner M; Hall GB; Soares CN; Frey BN
[Ad] Endereço:Women's Health Concerns Clinic, St. Joseph's Healthcare Hamilton, 100 West 5th Street, Suite C124, Hamilton, ON, Canada L8N 3K7; MiNDS Neuroscience Graduate Program, McMaster University, 1280 Main St. W., Hamilton, ON, Canada. Electronic address: slyepcha@mcmaster.ca.
[Ti] Título:Subtle persistent working memory and selective attention deficits in women with premenstrual syndrome.
[So] Source:Psychiatry Res;249:354-362, 2017 Mar.
[Is] ISSN:1872-7123
[Cp] País de publicação:Ireland
[La] Idioma:eng
[Ab] Resumo:As a recurrent, cyclical phenomenon, premenstrual syndrome (PMS) affects a significant proportion of women of the reproductive age, and leads to regular monthly days of functional impairment. Symptoms of PMS include somatic and psychological symptoms, such as headaches, sleep disturbances, social withdrawal and mood changes, during the late luteal phase of the menstrual cycle, which alleviate during the follicular phase. This study investigated neurocognitive functioning in women with moderate to severe PMS symptoms (n=13) compared to women with mild/no PMS (n=27) through administration of a battery of neuropsychological tests during the asymptomatic follicular phase of the menstrual cycle. Relative to women with mild/no PMS symptoms, women with moderate to severe PMS showed significantly poorer accuracy and more errors of omission on the N-0-back, as well as more errors of omission on the N-2-back task, indicating the presence of impairment in selective attention and working memory. This study provides evidence of persistent, subtle working memory and selective attention difficulties in those with moderate to severe PMS during the follicular phase of the menstrual cycle.
[Mh] Termos MeSH primário: Atenção/fisiologia
Transtornos da Memória/psicologia
Memória de Curto Prazo/fisiologia
Síndrome Pré-Menstrual/psicologia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Feminino
Fase Folicular/psicologia
Seres Humanos
Fase Luteal/psicologia
Transtornos da Memória/diagnóstico
Ciclo Menstrual/psicologia
Testes Neuropsicológicos
Síndrome Pré-Menstrual/diagnóstico
Transtornos do Sono-Vigília/diagnóstico
Transtornos do Sono-Vigília/psicologia
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171108
[Lr] Data última revisão:
171108
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170203
[St] Status:MEDLINE


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[PMID]:28139071
[Au] Autor:Lee S; Lee SH; Yang BK; Park CK
[Ad] Endereço:College of Animal Life Sciences, Kangwon National University, Chuncheon, Republic of Korea.
[Ti] Título:The expression of VEGF, myoglobin and CRP2 proteins regulating endometrial remodeling in the porcine endometrial tissues during follicular and luteal phase.
[So] Source:Anim Sci J;88(9):1291-1297, 2017 Sep.
[Is] ISSN:1740-0929
[Cp] País de publicação:Australia
[La] Idioma:eng
[Ab] Resumo:Endometrial remodeling is important for successful embryo development and implantation in pigs. Therefore, this study investigated change of proteins regulating endometrial remodeling on follicular and luteal phase in porcine endometrial tissues. The endometrial tissue samples were collected from porcine uterus during follicular and luteal phase, vascular endothelial growth factor (VEGF), myoglobin and cysteine-rich protein 2 (CRP2) proteins were expressed by immnofluorescence, immunoblotting, and determined by 2-DE and MALDI-TOF/MS. We found that VEGF, myoglobin and CRP2 were strongly localized in endometrial tissues during luteal phase, but not follicular phase. The protein levels of VEGF, myoglobin and CRP2 in endometrial tissues were higher than luteal phase (P < 0.05). These results may provide understanding of intrauterine environment during estrous cycle in pigs, and will be used in animal reproduction for developing specific biomarkers in the future.
[Mh] Termos MeSH primário: Proteína beta Intensificadora de Ligação a CCAAT/metabolismo
Endométrio/metabolismo
Fase Folicular/genética
Fase Folicular/metabolismo
Fase Luteal/genética
Fase Luteal/metabolismo
Mioglobina/metabolismo
Suínos/metabolismo
Suínos/fisiologia
Fator A de Crescimento do Endotélio Vascular/metabolismo
[Mh] Termos MeSH secundário: Animais
Proteína beta Intensificadora de Ligação a CCAAT/fisiologia
Implantação do Embrião/genética
Implantação do Embrião/fisiologia
Desenvolvimento Embrionário/genética
Desenvolvimento Embrionário/fisiologia
Ciclo Estral/genética
Ciclo Estral/fisiologia
Feminino
Mioglobina/fisiologia
Fator A de Crescimento do Endotélio Vascular/fisiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (CCAAT-Enhancer-Binding Protein-beta); 0 (Myoglobin); 0 (Vascular Endothelial Growth Factor A)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171005
[Lr] Data última revisão:
171005
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170201
[St] Status:MEDLINE
[do] DOI:10.1111/asj.12774



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