Base de dados : MEDLINE
Pesquisa : G09.772.982 [Categoria DeCS]
Referências encontradas : 596 [refinar]
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[PMID]:28049450
[Au] Autor:Eguibar JR; Uribe CA; Cortes C; Bautista A; Gallup AC
[Ad] Endereço:Research Office of the Vice Rectory of Research and Postgraduate Studies, Benemérita Universidad Autónoma de Puebla, 4 Sur # 104. Col. Centro, 72000, Puebla, Pue., Mexico. jose.eguibar@correo.buap.mx.
[Ti] Título:Yawning reduces facial temperature in the high-yawning subline of Sprague-Dawley rats.
[So] Source:BMC Neurosci;18(1):3, 2017 Jan 03.
[Is] ISSN:1471-2202
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Yawning is a stereotyped behavior that enhances blood flow to the skull, and the resulting counterflow has been hypothesized as a mechanism for brain cooling. Studies have shown that yawns are strongly associated with physiological and pathological conditions that increase brain temperature, and that they are followed by equivalent decreases in brain temperature. However, measured reductions in cranial or facial temperatures following yawning have yet to be reported, to our knowledge. To accomplish this, we used a subline of Sprague-Dawley rats that yawn at a much greater rate (20 yawns/h) than do outbred Sprague-Dawley rats (2 yawns/h). RESULTS: Using an infrared camera, we effectively evaluated thermal changes in the cornea and concha of these rats before, during, and after yawns. The maximum temperature in both regions significantly decreased 10 s following yawns (concha: -0.3 °C, cornea: -0.4 °C), with a return to basal temperatures after 20 s. CONCLUSIONS: This study is the first clear demonstration of yawning-induced thermal cooling on the surface of the face, providing convergent evidence that this behavior plays a functional role in thermoregulation. As other studies have demonstrated that yawning is capable of reducing cortical brain temperature, our current data support the idea that yawning functions as a thermoregulator, affecting all structures within the head.
[Mh] Termos MeSH primário: Regulação da Temperatura Corporal
Face/fisiologia
Bocejo
[Mh] Termos MeSH secundário: Animais
Temperatura Corporal
Masculino
Ratos
Ratos Sprague-Dawley
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170915
[Lr] Data última revisão:
170915
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170105
[St] Status:MEDLINE
[do] DOI:10.1186/s12868-016-0330-3


  2 / 596 MEDLINE  
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[PMID]:27960124
[Au] Autor:Joshi S; Bayat A; Gagnon L; Shields DC; Koubeissi MZ
[Ad] Endereço:Department of Neurology, George Washington University, 2150 Pennsylvania Avenue, 9th Floor, Washington, D.C. 20037, USA.
[Ti] Título:Yawning induced by focal electrical stimulation in the human brain.
[So] Source:Epilepsy Behav;66:1-3, 2017 Jan.
[Is] ISSN:1525-5069
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The primary function of yawning is not fully understood. We report a case in which electrical stimulation of the putamen in the human brain consistently elicited yawning. A 46-year-old woman with intractable epilepsy had invasive depth electrode monitoring and cortical stimulation mapping as part of her presurgical epilepsy evaluation. The first two contacts of a depth electrode that was intended to sample the left insula were in contact with the putamen. Stimulation of these contacts at 6mA and 8mA consistently elicited yawning on two separate days. Engagement in arithmetic and motor tasks during stimulation did not result in yawning. When considering the role of the putamen in motor control and its extensive connectivity to cortical and brainstem regions, our findings suggest that it plays a key role in the execution of motor movements necessitated by yawning. Furthermore, given the role of the anterior insula in attention and focused tasks, activation of this area while engaged in arithmetic and motor tasks could inhibit the putaminal processing necessary for yawning. Many have hypothesized the function of yawning; however, it remains debatable whether yawning serves a primarily physiological or communicative function or perhaps both.
[Mh] Termos MeSH primário: Putamen/fisiologia
Bocejo/fisiologia
[Mh] Termos MeSH secundário: Estimulação Elétrica
Epilepsia/diagnóstico
Feminino
Seres Humanos
Neuroestimuladores Implantáveis
Meia-Idade
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170904
[Lr] Data última revisão:
170904
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161214
[St] Status:MEDLINE


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[PMID]:27748979
[Au] Autor:Antoun JS; Thomson WM; Merriman TR; Farella M
[Ad] Endereço:Department of Oral Sciences, Sir John Walsh Research Institute, University of Otago, Dunedin, New Zealand.
[Ti] Título:Self-reported oral behaviour habits in hyperdivergent and normodivergent facial types.
[So] Source:J Oral Rehabil;44(1):16-21, 2017 Jan.
[Is] ISSN:1365-2842
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The relationship between facial morphology and jaw function remains controversial. The purpose of this study was to investigate differences in self-reported oral behaviour habits between individuals with normodivergent and hyperdivergent facial types. Some 80 cases and controls were individually matched on age, sex ethnicity and treatment stage. The participants were recruited from an orthodontic clinic, and included both adolescents and adults. Habitual oral activity was assessed using the Oral Behaviour Checklist (OBC) based on their experiences in the past 4 weeks. Univariate and bivariate analyses were performed. The sample had a mean age of 17·2 years (SD = 4·6; range = 12-49 years), and was predominantly female (65·0%) and of New Zealand European origin (91·3%). The prevalence of reporting one or more frequently performed habitual muscular behaviour in either study group was over 85% (P > 0·05). There was no difference in total OBC score between the hyperdivergent (25·6; SD: 9·0) and normodivergent group (25·3; SD: 9·9). Moreover, there was no difference in the prevalence of either nocturnal or daytime oral behaviours between the two groups. While this study did not include any objective measures of functional or habitual activity, we found no differences in self-reported oral behaviour habits between normodivergent and hyperdivergent individuals. The findings do not support an association between vertical facial form and habitual muscular activity.
[Mh] Termos MeSH primário: Face/anatomia & histologia
Ossos Faciais/anormalidades
Má Oclusão/fisiopatologia
Autorrelato
[Mh] Termos MeSH secundário: Adolescente
Adulto
Bruxismo/fisiopatologia
Criança
Arco Dental/fisiopatologia
Face/fisiologia
Face/fisiopatologia
Ossos Faciais/anatomia & histologia
Ossos Faciais/fisiopatologia
Feminino
Seres Humanos
Masculino
Mastigação/fisiologia
Meia-Idade
Nova Zelândia
Reprodutibilidade dos Testes
Comportamento Verbal/fisiologia
Dimensão Vertical
Bocejo/fisiologia
Adulto Jovem
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171020
[Lr] Data última revisão:
171020
[Sb] Subgrupo de revista:D; IM
[Da] Data de entrada para processamento:161018
[St] Status:MEDLINE
[do] DOI:10.1111/joor.12452


  4 / 596 MEDLINE  
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[PMID]:27605500
[Au] Autor:Yonezawa T; Sato K; Uchida M; Matsuki N; Yamazaki A
[Ad] Endereço:Department of Veterinary Medical Sciences, The University of Tokyo, Tokyo, Japan.
[Ti] Título:Presence of contagious yawning in sheep.
[So] Source:Anim Sci J;88(1):195-200, 2017 Jan.
[Is] ISSN:1740-0929
[Cp] País de publicação:Australia
[La] Idioma:eng
[Ab] Resumo:Contagious yawning is triggered by others yawning, and it has previously been reported in humans, primates and several experimental and companion mammals. Whereas it might be a response to an innate releasing mechanism, contagious yawning is also considered to involve emotional contagion. Here, we demonstrate that sheep, the animal model of livestock animals, also experience contagious yawning. Twelve adult castrated Corriedale sheep were used in this study. Pairs of sheep were adjacently restrained with or without a wooden divider panel to shield them from viewing the other. Their behaviors were video-recorded for 3 days in each condition. Sheep yawned 2.0 ± 1.1 and 1.2 ± 1.1 times/day/head in the unshielded and shielded conditions, respectively. Unshielded restrained sheep yawned within 1 min after the other one 11.1% of the time, while shielded pairs did not exhibit contagious yawning. Rumination was also highly synchronized under the unshielded condition. These data reveal that contagious yawning and behavioral synchronicity occur in ruminants like sheep, making them a suitable animal model to investigate contagious yawning and the underlying mechanism.
[Mh] Termos MeSH primário: Comportamento Animal/fisiologia
Ovinos/fisiologia
Ovinos/psicologia
Bocejo/fisiologia
[Mh] Termos MeSH secundário: Animais
Emoções/fisiologia
Seres Humanos
Masculino
Modelos Animais
Estimulação Luminosa
Rúmen/fisiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170316
[Lr] Data última revisão:
170316
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160909
[St] Status:MEDLINE
[do] DOI:10.1111/asj.12681


  5 / 596 MEDLINE  
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[PMID]:28269356
[Au] Autor:Yu-Lung Chang; Yen-Cheng Feng; Chen OT
[Ti] Título:Real-time physiological and facial monitoring for safe driving.
[So] Source:Conf Proc IEEE Eng Med Biol Soc;2016:4849-4852, 2016 08.
[Is] ISSN:1557-170X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:This work is to develop an intelligent driver-assistance system which can perceive the physiological state of a driver to avoid fatigue driving. The proposed system includes a camera, a wireless ElectroCardioGram (ECG) sensor patch, and a computation platform. The camera in front of a driver is to catch a face image which is processed to obtain features of a mouth for identifying a yawn. The sensor patch records ECG signals which are computed to yield six Heart Rate Variability (HRV) parameters. Seven healthy subjects of 6 males and 1 female had individually driven a car, which was embedded with our system, for 3 hours at a well-known route, mostly in a freeway road. Based on the captured video and measured ECG signals, the correlations between the yawning frequency and six HRV parameters are investigated by using the regression method to discover that the ratio (LF/HF) of Low-Frequency (LF) spectrum power over High-Frequency (HF) spectrum power yields the relatively highest correlation. In order to effectively identity driver's fatigue, the variations of differential LF/HF are further characterized to attain two thresholds which are accompanied with yawning frequencies to build a fair detection mechanism. The practical road tests demonstrate that the proposed system is very feasible and easily adapted to different drivers.
[Mh] Termos MeSH primário: Condução de Veículo
Eletrocardiografia/métodos
Fadiga/diagnóstico
Bocejo/fisiologia
[Mh] Termos MeSH secundário: Adulto
Face/fisiologia
Feminino
Voluntários Saudáveis
Frequência Cardíaca/fisiologia
Seres Humanos
Masculino
Gravação em Vídeo
Tecnologia sem Fio/instrumentação
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1707
[Cu] Atualização por classe:171126
[Lr] Data última revisão:
171126
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170309
[St] Status:MEDLINE
[do] DOI:10.1109/EMBC.2016.7591813


  6 / 596 MEDLINE  
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[PMID]:27542092
[Au] Autor:Górecka-Bruzda A; Fureix C; Ouvrard A; Bourjade M; Hausberger M
[Ad] Endereço:Department of Animal Behaviour, Institute of Genetics and Animal Breeding, Polish Academy of Sciences, Jastrzebiec, Poland. a.gorecka@ighz.pl.
[Ti] Título:Investigating determinants of yawning in the domestic (Equus caballus) and Przewalski (Equus ferus przewalskii) horses.
[So] Source:Naturwissenschaften;103(9-10):72, 2016 Oct.
[Is] ISSN:1432-1904
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:Yawning is rare in herbivores which therefore may be an interesting group to disentangle the potential function(s) of yawning behaviour. Horses provide the opportunity to compare not only animals living in different conditions but also wild versus domestic species. Here, we tested three hypotheses by observing both domestic and Przewalski horses living in semi-natural conditions: (i) that domestic horses may show an elevated rate of yawning as a result of the domestication process (or as a result of life conditions), (ii) that individuals experiencing a higher level of social stress would yawn more than individuals with lower social stress and (iii) that males would yawn more often than females. The study involved 19 Przewalski horses (PHs) and 16 domestic horses (DHs) of different breeds living in large outdoor enclosures. The results showed that there was no difference between the PH and DH in yawning frequency (YF). PHs exhibited much higher levels of social interactions than DHs. There was a positive correlation between yawning frequency and aggressive behaviours in PHs, especially males, supporting the idea that yawning may be associated with more excitatory/stressful social situations. A correlation was found between yawning frequency and affiliative behaviours in DHs, which supports the potential relationship between yawning and social context. Finally, the entire males, but not castrated males, showed much higher levels of yawning than females in both species. The intensity (rather than the valence) of the interaction may be important in triggering yawning, which could therefore be a displacement activity that helps reduce tension.
[Mh] Termos MeSH primário: Agressão/fisiologia
Cavalos/fisiologia
Bocejo/fisiologia
[Mh] Termos MeSH secundário: Animais
Animais Domésticos
Animais Selvagens
Comportamento Animal/fisiologia
Cruzamento
Feminino
Cavalos/psicologia
Masculino
Orquiectomia/veterinária
Fatores Sexuais
Especificidade da Espécie
Estresse Psicológico/fisiopatologia
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170224
[Lr] Data última revisão:
170224
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160820
[St] Status:MEDLINE
[do] DOI:10.1007/s00114-016-1395-7


  7 / 596 MEDLINE  
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[PMID]:27128474
[Au] Autor:Kaplan SE; Ohrbach R
[Ti] Título:Self-Report of Waking-State Oral Parafunctional Behaviors in the Natural Environment.
[So] Source:J Oral Facial Pain Headache;30(2):107-19, 2016.
[Is] ISSN:2333-0384
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:AIMS: To determine if retrospective self-report of oral parafunctional behaviors potentially relevant to pain conditions is valid, by comparing oral parafunctional behaviors via a self-report instrument (Oral Behaviors Checklist [OBC]) with in-field reports of oral parafunction. METHODS: Individuals with a range of oral parafunctional behaviors, as identified by the OBC, were recruited, and 22 completed the field study. Using the Ecological Momentary Assessment paradigm, each subject was randomly prompted about eight times per day, for a target of 7 days, via portable handheld computer to report current behaviors among 11 queried items. Before and after the field study, a paper version of the OBC was administered. Separately, 74 individuals participated in a test-retest study of the paper OBC. Analyses included regression, correlation, intraclass correlation coefficient (ICC) and area under the receiving operating curve (AUC). RESULTS: Pre- and postfield study administration of the OBC exhibited substantial reliability (ICC = 0.65), indicating no reactivity during the intervening in-field data collection. Reliability across in-field days was low, indicating high variability in which behavior occurred on which day. Nonobservable behaviors were reported more frequently than observable behaviors. Self-report via OBC was linear with in-field data collection methods (R2 values ranged from 0.1 to 0.7; most values were within 0.3 to 0.4). The predictive value of the self-report total score was AUC (0.88) relative to the in-field study score. Separate test-retest reliability of the OBC was almost perfect (ICC = 0.88). CONCLUSIONS: The OBC is a reliable and valid way to predict behaviors in the natural environment and will be useful for further pain research.
[Mh] Termos MeSH primário: Dor Facial/psicologia
Autorrelato/normas
[Mh] Termos MeSH secundário: Adulto
Área Sob a Curva
Bruxismo/psicologia
Lista de Checagem
Goma de Mascar
Computadores de Mão
Oclusão Dentária Traumática/psicologia
Feminino
Seres Humanos
Masculino
Má Oclusão/psicologia
Músculos da Mastigação/fisiologia
Registros Médicos
Meia-Idade
Contração Muscular/fisiologia
Valor Preditivo dos Testes
Curva ROC
Reprodutibilidade dos Testes
Estudos Retrospectivos
Hábitos Linguais/psicologia
Bocejo
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Chewing Gum)
[Em] Mês de entrada:1607
[Cu] Atualização por classe:160430
[Lr] Data última revisão:
160430
[Sb] Subgrupo de revista:D
[Da] Data de entrada para processamento:160430
[St] Status:MEDLINE
[do] DOI:10.11607/ofph.1592


  8 / 596 MEDLINE  
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[PMID]:26980063
[Au] Autor:Flaskerud JH
[Ad] Endereço:a University of California, School of Nursing , Los Angeles , California , USA.
[Ti] Título:Yawning, Why and When?
[So] Source:Issues Ment Health Nurs;37(7):526-9, 2016 Jul.
[Is] ISSN:1096-4673
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Bocejo
[Mh] Termos MeSH secundário: Animais
Transtorno da Personalidade Antissocial
Seres Humanos
Bocejo/fisiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170717
[Lr] Data última revisão:
170717
[Sb] Subgrupo de revista:N
[Da] Data de entrada para processamento:160317
[St] Status:MEDLINE
[do] DOI:10.3109/01612840.2015.1111475


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[PMID]:26643378
[Au] Autor:Laurell K; Artto V; Bendtsen L; Hagen K; Häggström J; Linde M; Söderström L; Tronvik E; Wessman M; Zwart JA; Kallela M
[Ad] Endereço:Department of Pharmacology and Clinical Neuroscience, Umeå University, Sweden Katarina.Laurell@neuro.umu.se.
[Ti] Título:Premonitory symptoms in migraine: A cross-sectional study in 2714 persons.
[So] Source:Cephalalgia;36(10):951-9, 2016 Sep.
[Is] ISSN:1468-2982
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:AIM: To describe the frequency and number of premonitory symptoms (PS) in migraine, the co-occurrence of different PS, and their association with migraine-related factors. METHODS: In this cross-sectional study, a validated questionnaire was sent to Finnish migraine families between 2002 and 2013 to obtain data on 14 predefined PS, migraine diagnoses, demographic factors, and migraine characteristics. The estimated response rate was 80%. RESULTS: Out of 2714 persons, 2223 were diagnosed with migraine. Among these, 77% reported PS, with a mean number of 3.0 symptoms compared to 30% (p < 0.001) and 0.5 symptoms (p < 0.001) among 491 persons with non-migraine headaches. Yawning was the most commonly reported symptom (34%) among migraineurs. Females reported PS more frequently than males (81 versus 64%, p < 0.001) and experienced a higher number of different symptoms (mean 3.3 versus 1.8, p < 0.001). All measures of migraine severity were associated with a higher burden of PS. Light and sound sensitivity showed the highest co-occurrence (kappa = 0.51, 95% CI 0.47-0.55). In a generalized linear model, age, gender, higher frequency, duration and intensity of headache, reduced working capacity, most aura symptoms, and associated symptoms of the headache phase were significantly associated with an increased in the number of PS. CONCLUSION: PS are experienced by a majority of migraineurs. More severe migraine is associated with a higher burden of PS. Since the material was not entirely representative of the general population of migraineurs, caution should be exercised in generalizing the results.
[Mh] Termos MeSH primário: Letargia/diagnóstico
Letargia/epidemiologia
Transtornos de Enxaqueca/diagnóstico
Transtornos de Enxaqueca/epidemiologia
Bocejo
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Idoso de 80 Anos ou mais
Criança
Estudos Transversais
Feminino
Finlândia/epidemiologia
Seres Humanos
Masculino
Meia-Idade
Inquéritos e Questionários
Bocejo/fisiologia
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151209
[St] Status:MEDLINE
[do] DOI:10.1177/0333102415620251


  10 / 596 MEDLINE  
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[PMID]:26534942
[Au] Autor:Collins GT; Gerak LR; Javors MA; France CP
[Ad] Endereço:Departments of Pharmacology (G.T.C., L.R.G., M.A.J., C.P.F.) and Psychiatry (M.A.J., C.P.F.), University of Texas Health Science Center, San Antonio, Texas; and South Texas Veterans Health Care System, San Antonio, Texas (G.T.C.).
[Ti] Título:Lorcaserin Reduces the Discriminative Stimulus and Reinforcing Effects of Cocaine in Rhesus Monkeys.
[So] Source:J Pharmacol Exp Ther;356(1):85-95, 2016 Jan.
[Is] ISSN:1521-0103
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Cocaine abuse and obesity are serious public health problems, and studies suggest that both dopamine and serotonin systems are involved in regulating the consumption of drugs and food. Lorcaserin has serotonin (5-HT)2C receptor agonist actions, is approved by the U.S. Food and Drug Administration for treating obesity, and might be effective for treating cocaine abuse. These studies characterized the pharmacokinetic and behavioral profiles of lorcaserin (intragastric administration) and determined the effectiveness of lorcaserin to alter discriminative stimulus and reinforcing effects of cocaine (intravenous administration) in rhesus monkeys. Administered acutely, lorcaserin dose-dependently increased the occurrence of yawning while decreasing spontaneous activity and operant responding for food. These effects appeared within 30-60 minutes of administration and began to dissipate by 240 minutes, a time course closely matching plasma concentrations of lorcaserin. In monkeys discriminating cocaine from saline, lorcaserin alone did not occasion cocaine-appropriate responding but shifted the cocaine dose-response curve to the right and down in two of three monkeys. When administered acutely, lorcaserin dose-dependently decreased the rate at which monkeys responded for infusions of cocaine. When administered chronically, 3.2 mg/kg lorcaserin reduced the rate of cocaine-maintained responding by 50% for the duration of a 14-day treatment period. Together, these results show that lorcaserin attenuates the discriminative stimulus effects of cocaine after acute administration and the reinforcing effects of cocaine after acute and repeated administration, consistent with the view that it might have utility in treating cocaine abuse.
[Mh] Termos MeSH primário: Fármacos Antiobesidade/farmacologia
Benzazepinas/farmacologia
Cocaína/antagonistas & inibidores
Cocaína/farmacologia
Discriminação (Psicologia)/efeitos dos fármacos
Receptor 5-HT2C de Serotonina/efeitos dos fármacos
Reforço (Psicologia)
Agonistas de Receptores de Serotonina/farmacologia
[Mh] Termos MeSH secundário: Administração Intravenosa
Animais
Fármacos Antiobesidade/farmacocinética
Comportamento Animal/efeitos dos fármacos
Benzazepinas/farmacocinética
Cocaína/farmacocinética
Transtornos Relacionados ao Uso de Cocaína/tratamento farmacológico
Condicionamento Operante/efeitos dos fármacos
Relação Dose-Resposta a Droga
Feminino
Alimentos
Intubação Gastrointestinal
Macaca mulatta
Masculino
Atividade Motora/efeitos dos fármacos
Autoadministração
Agonistas de Receptores de Serotonina/farmacocinética
Bocejo/efeitos dos fármacos
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL
[Nm] Nome de substância:
0 (Anti-Obesity Agents); 0 (Benzazepines); 0 (Receptor, Serotonin, 5-HT2C); 0 (Serotonin Receptor Agonists); 637E494O0Z (lorcaserin); I5Y540LHVR (Cocaine)
[Em] Mês de entrada:1603
[Cu] Atualização por classe:170220
[Lr] Data última revisão:
170220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151105
[St] Status:MEDLINE
[do] DOI:10.1124/jpet.115.228833



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