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  1 / 17 MEDLINE  
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Line, Sérgio Roberto Peres
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[PMID]:26895384
[Au] Autor:Soares AP; do Espírito Santo RF; Line SR; Pinto Md; Santos Pde M; Toralles MB; do Espírito Santo AR
[Ad] Endereço:Multidisciplinary Institute of Health, Federal University of Bahia - UFBA, Rua Rio de Contas, 58, Quadra 17, Lote 58, Candeias, Vitória da Conquista, BA CEP 45.029-094, Brazil. Electronic address: anapratess@hotmail.com.
[Ti] Título:Bisphosphonates: Pharmacokinetics, bioavailability, mechanisms of action, clinical applications in children, and effects on tooth development.
[So] Source:Environ Toxicol Pharmacol;42:212-7, 2016 Mar.
[Is] ISSN:1872-7077
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Bisphosphonates (BPs) avidly bind to calcium crystals and inhibit osteoclastic bone resorption, making them useful for treatment of skeletal disorders such as osteoporosis, Paget's disease, osteogenesis imperfecta and metastatic bone diseases. BPs therapeutically act by causing toxic effects on osteoclasts or interfering with specific intracellular pathways in those cells. BPs that possess nitrogen in their composition are called nitrogen-containing BPs (NBPs) and include alendronate, pamidronate, risedronate, ibandronate, and zoledronate. Simple BPs or non-NBPs do not have nitrogen in their composition, include etiodronate and clodronate, and were the first to be tested in animals and clinically used. Because BPs may be administered to pregnant women or children during deciduous and permanent teeth development, it is expected that they might disturb tooth eruption and development. A review of current literature on pharmacokinetics, bioavailability, mechanisms of action, and clinical applications of BPs in children, and their effects on tooth eruption and development is presented.
[Mh] Termos MeSH primário: Conservadores da Densidade Óssea/farmacologia
Fenômenos Fisiológicos Dentários/efeitos dos fármacos
Difosfonatos/farmacologia
[Mh] Termos MeSH secundário: Conservadores da Densidade Óssea/metabolismo
Conservadores da Densidade Óssea/uso terapêutico
Difosfonatos/metabolismo
Difosfonatos/uso terapêutico
Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T; REVIEW
[Nm] Nome de substância:
0 (Bone Density Conservation Agents); 0 (Diphosphonates)
[Em] Mês de entrada:1612
[Cu] Atualização por classe:161230
[Lr] Data última revisão:
161230
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160220
[St] Status:MEDLINE


  2 / 17 MEDLINE  
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[PMID]:24872853
[Au] Autor:Ratzmann A; Ruge S; Ostendorf K; Kordass B
[Ad] Endereço:Universitätsmedizin Greifswald, Zahnmedizinische Propädeutik/Community Dentristry, Greifswald, Deutschland.
[Ti] Título:Designing post-graduate Master's degree programs: the advanced training program in Dental Functional Analysis and Therapy as one example.
[So] Source:GMS Z Med Ausbild;31(2):Doc18, 2014.
[Is] ISSN:1860-3572
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: The decision to consolidate European higher education was reached by the Bologna Conference. Based on the Anglo-American system, a two-cycle degree program (Bachelor and Master) has been introduced. Subjects culminating in a state examination, such as Medicine and Dentistry, were excluded from this reform. Since the state examination is already comparable in its caliber to a Master's degree in Medicine or Dentistry, only advanced Master's degree programs with post-graduate specializations come into consideration for these subjects. In the field of dentistry numerous post-graduate study programs are increasingly coming into existence. Many different models and approaches are being pursued. METHOD: Since the 2004-2005 winter semester, the University of Greifswald has offered the Master's degree program in Dental Functional Analysis and Therapy. Two and a half years in duration, this program is structured to allow program participation while working and targets licensed dentists who wish to attain certified skills for the future in state-of-the-art functional analysis and therapy. AIM: The design of this post-graduate program and the initial results of the evaluation by alumni are presented here. CONCLUSION: Our experiences show that the conceptual idea of an advanced Master's program has proved successful. The program covers a specialty which leads to increased confidence in handling challenging patient cases. The sharing of experiences among colleagues was evaluated as being especially important.
[Mh] Termos MeSH primário: Competência Clínica
Fenômenos Fisiológicos Dentários
Educação Continuada em Odontologia/organização & administração
Educação de Pós-Graduação em Odontologia/organização & administração
Terapia Assistida por Computador/educação
[Mh] Termos MeSH secundário: Currículo
Alemanha
Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1510
[Cu] Atualização por classe:140529
[Lr] Data última revisão:
140529
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140530
[St] Status:MEDLINE
[do] DOI:10.3205/zma000910


  3 / 17 MEDLINE  
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[PMID]:23017987
[Au] Autor:Martin RD
[Ad] Endereço:Department of Anthropology, The Field Museum, Chicago 60605-2496, USA. rdmartin@fieldmuseum.org
[Ti] Título:Primates.
[So] Source:Curr Biol;22(18):R785-90, 2012 Sep 25.
[Is] ISSN:1879-0445
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Evolução Biológica
Primatas
[Mh] Termos MeSH secundário: Animais
Fenômenos Fisiológicos Dentários
Fósseis
Geografia
Mitocôndrias/genética
Primatas/anatomia & histologia
Primatas/classificação
Primatas/genética
Primatas/fisiologia
Meio Social
Dente
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1304
[Cu] Atualização por classe:120928
[Lr] Data última revisão:
120928
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:120929
[St] Status:MEDLINE


  4 / 17 MEDLINE  
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[PMID]:22755470
[Au] Autor:Rythén M
[Ad] Endereço:Department of Pediatric Dentistry, Institute of Odontology, Sahlgrenska Academy, University of Gothenburg Gothenburg, Sweden. marianne.rythen@vgregion.se
[Ti] Título:Preterm infants--odontological aspects.
[So] Source:Swed Dent J Suppl;(224):2p preceding i-vi, 1-106, 2012.
[Is] ISSN:0348-6672
[Cp] País de publicação:Sweden
[La] Idioma:eng
[Ab] Resumo:Preterm birth is associated with medical complications and treatments postnatally and disturbances in growth and development. Primary and permanent teeth develop during this postnatal period. The overall aim of the present thesis was to elucidate the effects of preterm birth and postnatal complications on oral health and the dentoalveolar development during adolescence, and to study the effects of preterm birth on caries during childhood, in a well-defined group of preterm infants. In the same group, explore the development of the primary and permanent teeth and compare the results with a matched control group and control teeth. The subjects consisted of 40 (45) of 56 surviving infants, born < 29 weeks of gestational age (GA), and matched healthy children born at term. The material consisted of 44 teeth from 14 of the preterm adolescents and 36 control teeth from healthy children. Clinical examinations and dental cast analysis were performed during adolescence and morbidity was noted. Retrospective information from medical and dental records was obtained. Dental enamel was analyzed in a polarized light microscopy, and scanning electron microscopy. Further, chemical analyses of enamel and dentin were performed with X-ray microanalysis. The results showed that during adolescence, more preterms had plaque and gingival inflammation, lower salivary secretion, more S. mutans and severe hypomineralization. Retrospectively, less caries was noted at six years of age, but more children had hypomineralization in the primary dentition. Angle Class II malocclusion, large over-bite and deep bite associated with medical diagnoses were frequent. Furthermore, smaller dental arch perimeters in girls, at 16 years of age, and smaller tooth size in the incisors, canines and first molars were found. The morphological findings were confirmed in the XRMA analyses. In postnatal enamel, varying degrees of porosities > 5% and incremental lines were seen. Lower values of Ca and Ca/C ratio and higher values of C were found. Ca/P ratio in both enamel and dentine indicates normal hydroxyapatite in both groups. No single medical diagnosis, postnatal treatment or morbidity in adolescents could explain the findings. As a conclusion, there are indications for poor oral outcome in this group of preterm infants during adolescence, and disturbed mineralization in primary teeth.
[Mh] Termos MeSH primário: Fenômenos Fisiológicos Dentários
Recém-Nascido Prematuro/fisiologia
[Mh] Termos MeSH secundário: Adolescente
Estudos de Casos e Controles
Criança
Pré-Escolar
Arco Dental/crescimento & desenvolvimento
Esmalte Dentário/química
Hipoplasia do Esmalte Dentário/fisiopatologia
Dentição Permanente
Feminino
Seres Humanos
Recém-Nascido
Masculino
Má Oclusão/fisiopatologia
Anormalidades Dentárias/fisiopatologia
Calcificação de Dente/fisiologia
Dente Decíduo
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1207
[Cu] Atualização por classe:131121
[Lr] Data última revisão:
131121
[Sb] Subgrupo de revista:D; IM
[Da] Data de entrada para processamento:120705
[St] Status:MEDLINE


  5 / 17 MEDLINE  
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[PMID]:21618268
[Au] Autor:Maxwell EE; Caldwell MW; Lamoureux DO; Budney LA
[Ad] Endereço:Staatliches Museum für Naturkunde, Rosenstein 1, 70191 Stuttgart, Germany. emaxwell@ualberta.ca
[Ti] Título:Histology of tooth attachment tissues and plicidentine in Varanus (Reptilia: Squamata), and a discussion of the evolution of amniote tooth attachment.
[So] Source:J Morphol;272(10):1170-81, 2011 Oct.
[Is] ISSN:1097-4687
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Few recent studies have examined the histological basis for tooth attachment in squamates. In the past few years, a surge of interest in this topic has led to the intriguing suggestion that the major tissues derived from the tooth germ (enamel, dentine, cementum and alveolar bone), are conservative and are present in all amniotes. In this study, we describe the histology and development of the tooth attachment complex in Varanus rudicollis, the rough-neck monitor. We provide the first published evidence for the role of cementum and alveolar bone in tooth attachment in varanoid lizards. In Varanus, cementum is deposited on the external surface of the tooth root as well as at the base of the tooth, where it plays a role in the attachment of the tooth to the jawbone. Alveolar bone is also involved in tooth ankylosis. Our results support the hypothesis that the major tooth germ tissues are found in all amniotes. We provide insights into the structure and development of plicidentine, defined as infolding of the dentine around the tooth base. This feature is unique to varanoids among extant tetrapods and is the third tissue implicated in tooth attachment in Varanus. Plicidentine develops asymmetrically along the labial-lingual axis of a tooth. Varanus is characterized by the presence of both primary and higher-order lamellae, which anastomose to form a honeycomb-like surface that then interacts with the more basal attachment tissues.
[Mh] Termos MeSH primário: Dentina/ultraestrutura
Lagartos/anatomia & histologia
Dente/ultraestrutura
[Mh] Termos MeSH secundário: Animais
Evolução Biológica
Cemento Dentário/anatomia & histologia
Cemento Dentário/ultraestrutura
Esmalte Dentário/anatomia & histologia
Esmalte Dentário/ultraestrutura
Fenômenos Fisiológicos Dentários
Dente/anatomia & histologia
Alvéolo Dental/anatomia & histologia
Alvéolo Dental/ultraestrutura
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1201
[Cu] Atualização por classe:161125
[Lr] Data última revisão:
161125
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:110528
[St] Status:MEDLINE
[do] DOI:10.1002/jmor.10972


  6 / 17 MEDLINE  
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[PMID]:21523736
[Au] Autor:Hsieh SG; Hibbert S; Shaw P; Ahern V; Arora M
[Ad] Endereço:Westmead Centre for Oral Health, Children's Hospital at Westmead, Westmead, Australia. susan.hsieh@gmail.com
[Ti] Título:Association of cyclophosphamide use with dental developmental defects and salivary gland dysfunction in recipients of childhood antineoplastic therapy.
[So] Source:Cancer;117(10):2219-27, 2011 May 15.
[Is] ISSN:0008-543X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The aim of this study was to examine the effect of antineoplastic therapy on dental development and saliva function in recipients of childhood antineoplastic therapy. METHODS: Patients attending the long-term follow-up clinic at Children's Hospital at Westmead, NSW, Australia, were included if they had received treatment prior to 16 years of age and were in remission for more than 5 years. A dental examination and saliva test were performed for each participant. Holtta's Defect Index (HDI) was used to assess tooth aplasia, microdontia, and root-crown ratio on an orthopantomogram (OPG). Multivariable-adjusted regression analyses were used to estimate the association of patient characteristics and treatment modalities with dental outcomes. RESULTS: One hundred six participants (61% male) were recruited (response rate = 88%). The mean HDI score was 24.7 ± 17.8. A cumulative dose of cyclophosphamide >7500 mg/m(2) increased the HDI score by 13.06 (P = .01). Recipients of cyclophosphamide also had significantly increased odds of exhibiting very low saliva flow (<0.7 mL/min) (odds ratio = 12.43; 95% confidence interval, 2.08-74.35; P = .006). CONCLUSIONS: Children and adolescents who received high doses of cyclophosphamide were at increased risk of dental disturbances. Cyclophosphamide recipients were also at greater risk of exhibiting very low saliva flow. This study applied the HDI to patients receiving all forms of antineoplastic treatment and highlights the dose-dependent relation between cumulative dose of cyclophosphamide and dental disturbances.
[Mh] Termos MeSH primário: Antineoplásicos/efeitos adversos
Ciclofosfamida/efeitos adversos
Fenômenos Fisiológicos Dentários/efeitos dos fármacos
Doenças das Glândulas Salivares/induzido quimicamente
Dente/crescimento & desenvolvimento
[Mh] Termos MeSH secundário: Adolescente
Criança
Pré-Escolar
Cárie Dentária/epidemiologia
Seres Humanos
Masculino
Dente/efeitos dos fármacos
Anormalidades Dentárias/etiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Antineoplastic Agents); 8N3DW7272P (Cyclophosphamide)
[Em] Mês de entrada:1106
[Cu] Atualização por classe:161125
[Lr] Data última revisão:
161125
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:110428
[St] Status:MEDLINE
[do] DOI:10.1002/cncr.25704


  7 / 17 MEDLINE  
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[PMID]:20128191
[Au] Autor:Keim RG
[Ti] Título:A shift in paradigm.
[So] Source:J Clin Orthod;43(10):613-4, 2009 Oct.
[Is] ISSN:0022-3875
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Ortodontia Corretiva/tendências
Ortodontia/tendências
[Mh] Termos MeSH secundário: Cefalometria/métodos
Oclusão Dentária
Fenômenos Fisiológicos Dentários
Registros Odontológicos
Seres Humanos
Processamento de Imagem Assistida por Computador/métodos
Imagem Tridimensional/métodos
Planejamento de Assistência ao Paciente
[Pt] Tipo de publicação:COMMENT; EDITORIAL
[Em] Mês de entrada:1003
[Cu] Atualização por classe:161201
[Lr] Data última revisão:
161201
[Sb] Subgrupo de revista:D
[Da] Data de entrada para processamento:100205
[St] Status:MEDLINE


  8 / 17 MEDLINE  
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[PMID]:19950518
[Au] Autor:Norton LA
[Ad] Endereço:University of Connecticut School of Dental Medicine, Farmington, CT 06030-1725, USA. esnlan@comcast.net
[Ti] Título:Dental anomalies and pathology in sperm whale.
[So] Source:J Vet Dent;26(3):172-5, 2009.
[Is] ISSN:0898-7564
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Anormalidades Dentárias/veterinária
Dente/anatomia & histologia
Baleias
[Mh] Termos MeSH secundário: Animais
Fenômenos Fisiológicos Dentários
Feminino
Masculino
Doenças Periodontais/patologia
Doenças Periodontais/veterinária
Anormalidades Dentárias/patologia
Odontopatias/patologia
Odontopatias/veterinária
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1003
[Cu] Atualização por classe:170810
[Lr] Data última revisão:
170810
[Sb] Subgrupo de revista:D
[Da] Data de entrada para processamento:091203
[St] Status:MEDLINE


  9 / 17 MEDLINE  
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[PMID]:19370800
[Ti] Título:Considering cosmetic dentistry.
[So] Source:Johns Hopkins Med Lett Health After 50;21(1):6-7, 2009 Mar.
[Is] ISSN:1042-1882
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Estética Dentária
[Mh] Termos MeSH secundário: Fatores Etários
Fenômenos Fisiológicos Dentários
Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:0904
[Cu] Atualização por classe:161125
[Lr] Data última revisão:
161125
[Sb] Subgrupo de revista:K
[Da] Data de entrada para processamento:090418
[St] Status:MEDLINE


  10 / 17 MEDLINE  
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[PMID]:19206154
[Au] Autor:Osi A; Weishampel DB
[Ad] Endereço:Research Group for Paleontology, Hungarian Academy of Sciences-Hungarian Natural History Museum, Budapest 1083, Hungary. hungaros@freemail.hu
[Ti] Título:Jaw mechanism and dental function in the late cretaceous basal eusuchian Iharkutosuchus.
[So] Source:J Morphol;270(8):903-20, 2009 Aug.
[Is] ISSN:1097-4687
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Iharkutosuchus makadii is a basal eusuchian crocodylian with multicusped teeth discovered from the Upper Cretaceous of Hungary. Skull and dentition morphology indicates an active food processing for this crocodylian. First among crocodylians, a combination of different analyses, including cranial adductor muscle reconstruction, tooth wear pattern, and enamel microstructure studies, is applied here to support this hypothesis. Data provide unambiguous evidence for significant dental occlusion that was a result of a unique, transverse mandibular movement. Reconstruction of the jaw adductors demonstrates strong muscles responsible for slow but active jaw closure as the motor of transverse jaw movement; nevertheless muscles producing rapid jaw closure were reduced. Macrowear orientations show a dominantly transverse movement of the mandibles completed by a slight anteroposterior component. Along with quadrate morphology, macrowear further indicates that this motion was accomplished by alternate rotation of the mandibles about the quadrate condyles. Dental morphology and wear patterns suggest two types of power stroke: a slicing-crushing stroke associated dominantly with anterior tooth-food-tooth contact (with a low degree of transverse mandibular movement) during in the early stage of mastication, and a grinding stroke with significant posterior tooth-tooth contact and a dynamic transverse movement occurring later. The patterns of microwear show a diverse diet for Iharkutosuchus including both soft and hard items. This is also supported by the microstructure of the thick, wrinkled enamel built up mostly by poorly developed columnar units. Based on wear patterns, ontogenetic variation in feeding habits of Iharkutosuchus is also recognized.
[Mh] Termos MeSH primário: Jacarés e Crocodilos/anatomia & histologia
Jacarés e Crocodilos/fisiologia
Fenômenos Fisiológicos Dentários
Arcada Osseodentária/fisiologia
[Mh] Termos MeSH secundário: Animais
Esmalte Dentário/anatomia & histologia
Esmalte Dentário/ultraestrutura
Desgaste de Restauração Dentária
Fósseis
Hungria
Processamento de Imagem Assistida por Computador
Arcada Osseodentária/anatomia & histologia
Músculos da Mastigação/anatomia & histologia
Modelos Biológicos
Músculos Palatinos/anatomia & histologia
Paleodontologia
Dente/anatomia & histologia
Dente/ultraestrutura
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:0910
[Cu] Atualização por classe:091020
[Lr] Data última revisão:
091020
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:090212
[St] Status:MEDLINE
[do] DOI:10.1002/jmor.10726



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