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[PMID]:29272974
[Au] Autor:Melani AS; Sestini P; Rottoli P
[Ad] Endereço:a Fisiopatologia e Riabilitazione Respiratoria, Dipartimento Vasi, Cuore e Torace, Policlinico Le Scotte , Azienda Ospedaliera Universitaria Senese , Siena , Italy.
[Ti] Título:Home oxygen therapy: re-thinking the role of devices.
[So] Source:Expert Rev Clin Pharmacol;11(3):279-289, 2018 Mar.
[Is] ISSN:1751-2441
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: A range of devices are available for delivering and monitoring home oxygen therapy (HOT). Guidelines do not give indications for the choice of the delivery device but recommend the use of an ambulatory system in subjects on HOT whilst walking. Areas covered: We provide a clinical overview of HOT and review traditional and newer delivery and monitoring devices for HOT. Despite relevant technology advancements, clinicians, faced with many challenges when they prescribe oxygen therapy, often remain familiar to traditional devices and continuous flow delivery of oxygen. Some self-filling delivery-less devices could increase the users' level of independence with ecological advantage and, perhaps, reduced cost. Some newer portable oxygen concentrators are being available, but more work is needed to understand their performances in different diseases and clinical settings. Pulse oximetry has gained large diffusion worldwide and some models permit long-term monitoring. Some closed-loop portable monitoring devices are also able to adjust oxygen flow automatically in accordance with the different needs of everyday life. This might help to improve adherence and the practice of proper oxygen titration that has often been omitted because difficult to perform and time-consuming. Expert commentary: The prescribing physicians should know the characteristics of newer devices and use technological advancements to improve the practice of HOT.
[Mh] Termos MeSH primário: Serviços de Assistência Domiciliar
Oxigenoterapia/métodos
Oxigênio/administração & dosagem
[Mh] Termos MeSH secundário: Desenho de Equipamento
Seres Humanos
Oxigenoterapia/instrumentação
Cooperação do Paciente
Guias de Prática Clínica como Assunto
Padrões de Prática Médica
Caminhada
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
S88TT14065 (Oxygen)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180301
[Lr] Data última revisão:
180301
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171224
[St] Status:MEDLINE
[do] DOI:10.1080/17512433.2018.1421457


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[PMID]:27776000
[Au] Autor:Oyeyemi AL; Conway TL; Adedoyin RA; Akinroye KK; Aryeetey R; Assah F; Cain KL; Gavand KA; Kasoma SS; Kolbe-Alexander TL; Lambert EV; Larouche R; Moss SJ; Ocansey R; Onywera VO; Prista A; Tremblay MS; Sallis JF
[Ad] Endereço:1Department of Physiotherapy, University of Maiduguri, Maiduguri, NIGERIA; 2Physical Activity, Sport and Recreation, Faculty of Health Sciences, North-West University, Potchefstroom, SOUTH AFRICA; 3Department of Family Medicine and Public Health, University of California, San Diego, CA; 4Department of Medical Rehabilitation, Obafemi Awolowo University, Ile-Ife, NIGERIA; 5Nigerian Heart Foundation, Lagos, NIGERIA; 6School of Public Health, University of Ghana, Legon Accra, GHANA; 7Faculty of Medicine and Biomedical Sciences, Department of Public Health, University of Yaoundé I, Yaoundé, CAMEROON; 8Department of Biochemistry and Sports Science, School of Biosciences, Makerere University, Kampala, UGANDA; 9Centre for Research on Exercise, Physical Activity and Health, School of Human Movement and Nutrition Sciences, University of Queensland, Brisbane, AUSTRALIA; 10Division of Exercise Science and Sports Medicine, Department of Human Biology, University of Cape Town, SOUTH AFRICA; 11Children's Hospital of Eastern Ontario Research Institute, Ottawa, CANADA; 12Active Living and Wellness Alliance Group, Nungua, GHANA; 13Department of Recreation Management and Exercise Science, Kenyatta University, Nairobi, KENYA; 14Physical Activity and Health Research Group, CIDAF-FEFF, Universidade Pedagogica, Maputo, MOZAMBIQUE; and 15Department of Pediatrics, University of Ottawa, Ottawa, CANADA.
[Ti] Título:Construct Validity of the Neighborhood Environment Walkability Scale for Africa.
[So] Source:Med Sci Sports Exerc;49(3):482-491, 2017 Mar.
[Is] ISSN:1530-0315
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:PURPOSE: The development of valid measures of built environments relevant for physical activity is an important step toward controlling the global epidemic of physical inactivity-related noncommunicable diseases and deaths. This study assessed the construct validity of a self-report neighborhood environment walkability scale adapted for Africa (NEWS-Africa), by examining relationships with self-reported walking for transportation and recreation using pooled data from six sub-Saharan African countries. METHODS: NEWS was systematically adapted to assess urban, periurban, and rural environments in sub-Saharan Africa. Adults (n = 469, 18-85 yr, 49.7% women) from Cameroon, Ghana, Mozambique, Nigeria, South Africa, and Uganda were purposively recruited from neighborhoods varying in walkability and socioeconomic status, with some from villages. Participants completed the 76-item (13 subscales) NEWS-Africa by structured interview and reported weekly minutes of walking for transport and recreation using items from the International Physical Activity Questionnaire. RESULTS: The overall "walkability" index had a positive relationship with both walking for transportation (η = 0.020, P = 0.005) and recreation (η = 0.013, P = 0.028) in the pooled analyses. The mixed-use access and stranger danger scales were positively related with transport walking (η = 0.020, P = 0.006 and η = 0.021, P = 0.040, respectively). Proximity of recreational facilities (η = 0.016, P = 0.015), road/path connectivity (η = 0.025, P = 0.002), path infrastructure (η = 0.021, P = 0.005), and overall places for walking and cycling (η = 0.012, P = 0.029) scales were positively related to recreational walking. Country-specific results were mostly nonsignificant except for South Africa and Uganda. CONCLUSIONS: Of 14 NEWS-Africa scales, 7 were significantly related to walking behavior in pooled analyses, providing partial support for the construct validity of NEWS-Africa. However, effect sizes appeared to be lower than those from other continents. Further study with larger and more diverse samples is needed to determine whether the instrument performs well in each country.
[Mh] Termos MeSH primário: Planejamento Ambiental
Distribuição Espacial da População
Caminhada/estatística & dados numéricos
[Mh] Termos MeSH secundário: Adolescente
Adulto
África ao Sul do Saara/epidemiologia
Idoso
Idoso de 80 Anos ou mais
Feminino
Seres Humanos
Masculino
Meia-Idade
Recreação
Reprodutibilidade dos Testes
Autorrelato
Fatores Socioeconômicos
Transportes/estatística & dados numéricos
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; VALIDATION STUDIES
[Em] Mês de entrada:1710
[Cu] Atualização por classe:180301
[Lr] Data última revisão:
180301
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161025
[St] Status:MEDLINE
[do] DOI:10.1249/MSS.0000000000001131


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[PMID]:29370202
[Au] Autor:Rumble DD; Hurt CP; Brown DA
[Ad] Endereço:PhD in Rehabilitation Science Program, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
[Ti] Título:Step-by-step variability of swing phase trajectory area during steady state walking at a range of speeds.
[So] Source:PLoS One;13(1):e0191247, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Step kinematic variability has been characterized during gait using spatial and temporal kinematic characteristics. However, people can adopt different trajectory paths both between individuals and even within individuals at different speeds. Single point measures such as minimum toe clearance (MTC) and step length (SL) do not necessarily account for the multiple paths that the foot may take during the swing phase to reach the same foot fall endpoint. The purpose of this study was to test a step-by-step foot trajectory area (SBS-FTA) variability measure that is able to characterize sagittal plane foot trajectories of varying areas, and compare this measure against MTC and SL variability at different speeds. We hypothesize that the SBS-FTA variability would demonstrate increased variability with speed. Second, we hypothesize that SBS-FTA would have a stronger curvilinear fit compared with the CV and SD of SL and MTC. Third, we hypothesize SBS-FTA would be more responsive to change in the foot trajectory at a given speed compared to SL and MTC. Fourth, SBS-FTA variability would not strongly co-vary with SL and MTC variability measures since it represents a different construct related to foot trajectory area variability. METHODS: We studied 15 nonimpaired individuals during walking at progressively faster speeds. We calculated SL, MTC, and SBS-FTA area. RESULTS: SBS-FTA variability increased with speed, had a stronger curvilinear fit compared with the CV and SD of SL and MTC, was more responsive at a given speed, and did not strongly co-vary with SL and MTC variability measures. CONCLUSION: SBS foot trajectory area variability was sensitive to change with faster speeds, captured a relationship that the majority of the other measures did not demonstrate, and did not co-vary strongly with other measures that are also components of the trajectory.
[Mh] Termos MeSH primário: Caminhada/fisiologia
[Mh] Termos MeSH secundário: Idoso
Análise de Variância
Fenômenos Biomecânicos
Feminino
/fisiologia
Marcha/fisiologia
Seres Humanos
Masculino
Meia-Idade
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180226
[Lr] Data última revisão:
180226
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180126
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0191247


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[PMID]:29329344
[Au] Autor:Russell Esposito E; Miller RH
[Ad] Endereço:Center for the Intrepid, Brooke Army Medical Center, Department of Rehabilitation Medicine, JBSA, Ft. Sam Houston, Texas, United States of America.
[Ti] Título:Maintenance of muscle strength retains a normal metabolic cost in simulated walking after transtibial limb loss.
[So] Source:PLoS One;13(1):e0191310, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Recent studies on relatively young and fit individuals with limb loss suggest that maintaining muscle strength after limb loss may mitigate the high metabolic cost of walking typically seen in the larger general limb loss population. However, these data are cross-sectional and the muscle strength prior to limb loss is unknown, and it is therefore difficult to draw causal inferences on changes in strength and gait energetics. Here we used musculoskeletal modeling and optimal control simulations to perform a longitudinal study (25 virtual "subjects") of the metabolic cost of walking pre- and post-limb loss (unilateral transtibial). Simulations of walking were first performed pre-limb loss on a model with two intact biological legs, then post-limb loss on a model with a unilateral transtibial prosthesis, with a cost function that minimized the weighted sum of gait deviations plus metabolic cost. Metabolic costs were compared pre- vs. post-limb loss, with systematic modifications to the muscle strength and prosthesis type (passive, powered) in the post-limb loss model. The metabolic cost prior to limb loss was 3.44±0.13 J/m/kg. After limb loss, with a passive prosthesis the metabolic cost did not increase above the pre-limb loss cost if pre-limb loss muscle strength was maintained (mean -0.6%, p = 0.17, d = 0.17). With 10% strength loss the metabolic cost with the passive prosthesis increased (mean +5.9%, p < 0.001, d = 1.61). With a powered prosthesis, the metabolic cost was at or below the pre-limb loss cost for all subjects with strength losses of 10% and 20%, but increased for all subjects with strength loss of 30% (mean +5.9%, p < 0.001, d = 1.59). The results suggest that maintaining muscle strength may prevent an increase in the metabolic cost of walking following unilateral transtibial limb loss, and that a gait with minimal deviations can be achieved when muscle strength is sufficiently high, even when using a passive prosthesis.
[Mh] Termos MeSH primário: Amputados
Membros Artificiais
Força Muscular
Tíbia
Caminhada/fisiologia
[Mh] Termos MeSH secundário: Seres Humanos
Modelos Biológicos
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180226
[Lr] Data última revisão:
180226
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180113
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0191310


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[PMID]:29304163
[Au] Autor:Takeuchi Y
[Ad] Endereço:Department of Rehabilitation Science, Faculty of Health Care Science, Chiba Prefectural University of Health Sciences, Chuoku, Chiba, Japan.
[Ti] Título:A successful backward step correlates with hip flexion moment of supporting limb in elderly people.
[So] Source:PLoS One;13(1):e0190797, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:PURPOSE: The objective of this study was to determine the positional relationship between the center of mass (COM) and the center of pressure (COP) at the time of step landing, and to examine their relationship with the joint moments exerted by the supporting limb, with regard to factors of the successful backward step response. METHODS: The study population comprised 8 community-dwelling elderly people that were observed to take successive multi steps after the landing of a backward stepping. Using a motion capture system and force plate, we measured the COM, COP and COM-COP deviation distance on landing during backward stepping. In addition, we measured the moment of the supporting limb joint during backward stepping. The multi-step data were compared with data from instances when only one step was taken (single-step). Variables that differed significantly between the single- and multi-step data were used as objective variables and the joint moments of the supporting limb were used as explanatory variables in single regression analyses. RESULTS: The COM-COP deviation in the anteroposterior was significantly larger in the single-step. A regression analysis with COM-COP deviation as the objective variable obtained a significant regression equation in the hip flexion moment (R2 = 0.74). CONCLUSIONS: The hip flexion moment of supporting limb was shown to be a significant explanatory variable in both the PS and SS phases for the relationship with COM-COP distance. This study found that to create an appropriate backward step response after an external disturbance (i.e. the ability to stop after 1 step), posterior braking of the COM by a hip flexion moment are important during the single-limbed standing phase.
[Mh] Termos MeSH primário: Articulação do Quadril/fisiologia
Amplitude de Movimento Articular
Caminhada
[Mh] Termos MeSH secundário: Idoso
Feminino
Seres Humanos
Masculino
Meia-Idade
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180223
[Lr] Data última revisão:
180223
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180106
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0190797


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[PMID]:29195541
[Au] Autor:Marigliano E; Fahs PS; Ludden C
[Ti] Título:Walking for Heart Health: A Study of Adult Women in Rural New York.
[So] Source:Creat Nurs;22(4):268-275, 2016 Nov 01.
[Is] ISSN:1078-4535
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:PURPOSE: The study was undertaken to partially address the number one priority for Delaware County for 2013-2017: reducing chronic illness including heart disease and obesity (Delaware County Public Health, 2013). Thus, the purpose was to examine the effects of a 10-week walking program on outcomes, such as blood pressure (BP), total cholesterol (TC), high-density lipoprotein (HDL) levels, body mass index (BMI), 10-year cardiovascular risk, and results of a 6-minute walk test, for adult women in a rural community in New York. METHODS: A quasi-experimental study conducted 8 paired t tests of pre- and postdata using Bonferroni correction for multiple t tests. A convenience sample of 70 retained 62 to completion. Pre- and post-BMI, TC, HDL, BP, and a 6-minute walk test data were collected for each participant. Pedometer activity was collected throughout the program with computer downloads at 5 and 10 weeks. Sociodemographic variables including age, self-reported ethnicity, and educational level were used to describe the sample and trends in the data. FINDINGS: Age range was 29-79 years (M = 55) years. Mean pretest weight was 181 lb; mean BMI was 30.7 kg/m2. There was a statistically significant improvement (p < .05) in weight, BMI, TC, systolic blood pressure (SBP), and 6-minute walk test. All comparisons retained significance except TC after the Bonferroni correction. There was also a statistically significant increase (p < .05) in aerobic steps from midway to end of study after an incentive raffle challenge was introduced. CONCLUSIONS: The data suggest that a community walking program using pedometers with tracking capabilities was successful in increasing steps and improving select cardiovascular disease (CVD) risk factors in a group of women in a rural community in New York.
[Mh] Termos MeSH primário: Doenças Cardiovasculares/prevenção & controle
Promoção da Saúde/métodos
População Rural/estatística & dados numéricos
Caminhada/psicologia
Caminhada/estatística & dados numéricos
[Mh] Termos MeSH secundário: Adulto
Idoso
Feminino
Seres Humanos
Meia-Idade
New York
Fatores de Risco
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180220
[Lr] Data última revisão:
180220
[Sb] Subgrupo de revista:N
[Da] Data de entrada para processamento:171203
[St] Status:MEDLINE
[do] DOI:10.1891/1078-4535.22.4.268


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[PMID]:29304114
[Au] Autor:Chen Y; He L; Xu K; Li J; Guan B; Tang H
[Ad] Endereço:Department of Rehabilitation, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
[Ti] Título:Comparison of calf muscle architecture between Asian children with spastic cerebral palsy and typically developing peers.
[So] Source:PLoS One;13(1):e0190642, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To compare the muscle thickness, fascicle length, and pennation angle of the gastrocnemius, soleus, and tibialis anterior between Asian children with spastic cerebral palsy (CP) and typically developing (TD) peers. METHODS: This cross-sectional study involved a total of 72 children with hemiplegic CP (n = 24), and diplegic CP (n = 24) and their TD peers (n = 24). Muscle architecture was measured at rest using ultrasound. Clinical measures included gross motor function and a modified Ashworth scale. RESULTS: The thicknesses of the tibialis anterior and medial gastrocnemius muscles were smaller in the affected calf of children with CP (p<0.05) than in those of their TD peers. Additionally, the lengths of the lateral gastrocnemius and soleus fascicle were shorter (p<0.05) in children with diplegic CP than in their TD peers. The fascicle length was shorter in the affected calf of children with CP (p<0.05) than in the calves of their TD peers or the unaffected calf of children with hemiplegic CP. However, the length of the lateral gastrocnemius fascicle was similar between the two legs of children with hemiplegic CP. The pennation angles of the medial gastrocnemius and soleus muscles were larger (p<0.05) in the affected calf in children with hemiplegic CP than in the calves of their TD peers. The fascicle length of the lateral gastrocnemius and the thickness of the soleus muscle were positively correlated with gross motor function scores in children with CP (p<0.05). CONCLUSIONS: Muscle thickness and fascicle length were lower in the affected tibialis anterior, gastrocnemius, and soleus in children with spastic CP. These changes may limit the ability to stand and walk, and indicate a need to strengthen the affected muscle.
[Mh] Termos MeSH primário: Grupo com Ancestrais do Continente Asiático
Paralisia Cerebral/patologia
Músculo Esquelético/anatomia & histologia
Grupo Associado
[Mh] Termos MeSH secundário: Adolescente
Antropometria
Paralisia Cerebral/fisiopatologia
Criança
Pré-Escolar
Estudos Transversais
Feminino
Seres Humanos
Masculino
Músculo Esquelético/patologia
Músculo Esquelético/fisiopatologia
Caminhada
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180215
[Lr] Data última revisão:
180215
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180106
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0190642


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[PMID]:27779573
[Au] Autor:McAdams-DeMarco MA; Ying H; Olorundare I; King EA; Haugen C; Buta B; Gross AL; Kalyani R; Desai NM; Dagher NN; Lonze BE; Montgomery RA; Bandeen-Roche K; Walston JD; Segev DL
[Ad] Endereço:1 Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD. 2 Department of Epidemiology, Johns Hopkins School of Public Health, Baltimore, MD. 3 Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD. 4 Department of Biostatistics, Johns Hopkins School of Public Health, Baltimore, MD.
[Ti] Título:Individual Frailty Components and Mortality in Kidney Transplant Recipients.
[So] Source:Transplantation;101(9):2126-2132, 2017 09.
[Is] ISSN:1534-6080
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Frailty increases early hospital readmission and mortality risk among kidney transplantation (KT) recipients. Although frailty represents a high-risk state for this population, the correlates of frailty, the patterns of the 5 frailty components, and the risk associated with these patterns are unclear. METHODS: Six hundred sixty-three KT recipients were enrolled in a cohort study of frailty in transplantation (12/2008-8/2015). Frailty, activities of daily living (ADL)/instrumental ADL (IADL) disability, Centers for Epidemiologic Studies Depression Scale depression, education, and health-related quality of life (HRQOL) were measured. We used multinomial regression to identify frailty correlates. We identified which patterns of the 5 components were associated with mortality using adjusted Cox proportional hazards models. RESULTS: Frailty prevalence was 19.5%. Older recipients (adjusted prevalence ratio [PR], 2.22; 95% confidence interval [CI], 1.21-4.07) were more likely to be frail. The only other factors that were independently associated with frailty were IADL disability (PR, 3.22; 95% CI, 1.72-6.06), depressive symptoms (PR, 11.31; 95% CI, 4.02-31.82), less than a high school education (PR, 3.10; 95% CI, 1.30-7.36), and low HRQOL (fair/poor: PR, 3.71; 95% CI, 1.48-9.31). The most common pattern was poor grip strength, low physical activity, and slowed walk speed (19.4%). Only 2 patterns of the 5 components emerged as having an association with post-KT mortality. KT recipients with exhaustion and slowed walking speed (hazards ratio = 2.43; 95% CI, 1.17-5.03) and poor grip strength, exhaustion, and slowed walking speed (hazard ratio, 2.61; 95% CI, 1.14-5.97) were at increased mortality risk. CONCLUSIONS: Age was the only conventional factor associated with frailty among KT recipients; however, factors rarely measured as part of clinical practice, namely, HRQOL, IADL disability, and depressive symptoms, were significant correlates of frailty. Redefining the frailty phenotype may be needed to improve risk stratification for KT recipients.
[Mh] Termos MeSH primário: Idoso Fragilizado/psicologia
Nível de Saúde
Falência Renal Crônica/cirurgia
Transplante de Rim/mortalidade
Transplantados/psicologia
[Mh] Termos MeSH secundário: Atividades Cotidianas
Adolescente
Adulto
Fatores Etários
Idoso
Idoso de 80 Anos ou mais
Baltimore/epidemiologia
Depressão/diagnóstico
Depressão/mortalidade
Depressão/psicologia
Avaliação da Deficiência
Escolaridade
Tolerância ao Exercício
Feminino
Avaliação Geriátrica
Força da Mão
Seres Humanos
Falência Renal Crônica/diagnóstico
Falência Renal Crônica/mortalidade
Transplante de Rim/efeitos adversos
Masculino
Saúde Mental
Meia-Idade
Fenótipo
Valor Preditivo dos Testes
Prevalência
Estudos Prospectivos
Qualidade de Vida
Fatores de Risco
Inquéritos e Questionários
Fatores de Tempo
Resultado do Tratamento
Caminhada
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1710
[Cu] Atualização por classe:180215
[Lr] Data última revisão:
180215
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161026
[St] Status:MEDLINE
[do] DOI:10.1097/TP.0000000000001546


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[PMID]:28743505
[Au] Autor:Owusu C; Margevicius S; Schluchter M; Koroukian SM; Berger NA
[Ad] Endereço:Division of Hematology/Oncology, Department of Medicine, Case Western Reserve School of Medicine, United States; Case Comprehensive Cancer Center, Cleveland, OH, United States. Electronic address: Cynthia.owusu@case.edu.
[Ti] Título:Short Physical Performance Battery, usual gait speed, grip strength and Vulnerable Elders Survey each predict functional decline among older women with breast cancer.
[So] Source:J Geriatr Oncol;8(5):356-362, 2017 Sep.
[Is] ISSN:1879-4076
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To determine the ability of three performance-based measures [Short Physical Performance Battery (SPPB), gait speed, and Grip Strength] and a self-report measure [Vulnerable Elders Survey (VES-13)] to predict functional decline among older women with breast cancer. PATIENTS AND METHODS: Longitudinal data from a study of women ≥65years, with newly diagnosed stages I-III breast cancer, recruited from ambulatory oncology clinics between July 2010 and April 2014, was used. The primary outcome was functional decline, Yes or No, defined as a decrease in ≥1-point from baseline to 12months, on Activities of Daily Living Scales. Multivariable logistic regression and receiver operator curve analyses were conducted. RESULTS: Among 123 participants 18 (15%) developed functional decline. The predictive abilities for measures were: SPPB [Adjusted odds ratio (AOR)=1.65 per unit decrease in scores, 95% confidence interval (CI)=1.33-2.05; area under the receiver operator curve (AUC)=0.93; sensitivity=94%, specificity=80%]; gait speed (AOR=1.76 per unit increase in usual walking time, CI=1.29-2.41; AUC=0.93; sensitivity=87%, specificity=79%); VES-13 (AOR=1.64 per unit increase in scores, CI=1.31-2.05; AUC=0.87; sensitivity=83%, specificity=84%); and grip strength: (AOR=1.18 per unit decrease in grip strength, CI=1.06-1.30; AUC=0.80; sensitivity=67%, specificity=77%). CONCLUSION: SPPB, gait speed, grip strength and VES-13 all demonstrated excellent predictive abilities for functional decline. Larger studies are warranted to confirm the utility of these measures for identifying older adults with cancer at increased risk for functional decline, who may then be targeted for studies to explore the effects of interventions to improve function.
[Mh] Termos MeSH primário: Neoplasias da Mama/fisiopatologia
Marcha/fisiologia
Força da Mão/fisiologia
Caminhada/fisiologia
[Mh] Termos MeSH secundário: Atividades Cotidianas
Idoso
Idoso de 80 Anos ou mais
Feminino
Avaliação Geriátrica
Seres Humanos
Prognóstico
Estudos Prospectivos
Curva ROC
Autorrelato
[Pt] Tipo de publicação:COMPARATIVE STUDY; EVALUATION STUDIES; JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180212
[Lr] Data última revisão:
180212
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170727
[St] Status:MEDLINE


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[PMID]:28941716
[Au] Autor:Kim J; Garcia-Esquinas E; Navas-Acien A; Choi YH
[Ad] Endereço:Department of Preventive Medicine, Gachon University College of Medicine, Incheon, Republic of Korea. Electronic address: junghoonkim@gachon.ac.kr.
[Ti] Título:Blood and urine cadmium concentrations and walking speed in middle-aged and older U.S. adults.
[So] Source:Environ Pollut;232:97-104, 2018 Jan.
[Is] ISSN:1873-6424
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Reduced physical performance is an important feature of aging, and walking speed is a valid measure of physical performance and mobility in older adults. Previous epidemiological studies suggest that cadmium exposure, even at low environmental levels, may contribute to vascular, musculoskeletal, and cognitive dysfunction, which may all be associated with reductions in physical performance. To this end, we investigated the associations of blood and urine cadmium concentrations with walking speed in middle-aged and older adults in the U.S. general population. We studied U.S. adults from the National Health and Nutrition Examination Survey 1999 to 2002 who were ≥50 years of age, who had determinations of cadmium in blood or in urine, and who had measurements of the time taken to walk 20 feet. Walking speed (ft/sec) was computed as walked distance (20 ft) divided by measured time to walk (in seconds). The weighted geometric means of blood and urine cadmium were 0.49 [95% confidence interval (CI): 0.47, 0.52] µg/L and 0.37 (95% CI: 0.34, 0.42) ng/mL, respectively. After adjusting for sociodemographic, anthropometric, health-related behavioral, and clinical risk factors and inflammation markers, the highest (vs. lowest) quintile of blood cadmium was associated with a 0.18 (95% CI: 0.10, 0.25) ft/sec reduction in walking speed (p-Trend <0.001). No association was observed for urine cadmium levels with walking speed. Cadmium concentrations in blood, but not in urine, were associated with slower gait speed. Our findings add to the growing volume of evidence supporting cadmium's toxicity even at low levels of exposure.
[Mh] Termos MeSH primário: Cádmio/metabolismo
Cádmio/toxicidade
Exposição Ambiental/análise
Poluentes Ambientais/toxicidade
Velocidade de Caminhada/efeitos dos fármacos
[Mh] Termos MeSH secundário: Adulto
Idoso
Cádmio/sangue
Cádmio/urina
Exposição Ambiental/estatística & dados numéricos
Poluentes Ambientais/sangue
Poluentes Ambientais/metabolismo
Poluentes Ambientais/urina
Feminino
Seres Humanos
Masculino
Meia-Idade
Inquéritos Nutricionais
Fatores de Risco
Estados Unidos
Caminhada
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Environmental Pollutants); 00BH33GNGH (Cadmium)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180208
[Lr] Data última revisão:
180208
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170925
[St] Status:MEDLINE



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