Base de dados : MEDLINE
Pesquisa : G16.150 [Categoria DeCS]
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  1 / 96 MEDLINE  
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[PMID]:29315331
[Au] Autor:Invernizzi C; Nogueira E; Juri P; Santos E; Arredondo D; Branchiccela B; Mendoza Y; Antúnez K
[Ad] Endereço:Sección Etología, Instituto de Biología, Facultad de Ciencias, Montevideo, Uruguay.
[Ti] Título:Epormenis cestri secretions in Sebastiania schottiana trees cause mass death of honey bee Apis mellifera larvae in Uruguay.
[So] Source:PLoS One;13(1):e0190697, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:For more than 60 years, sporadic cases of massive summer honey bee larvae mortality in colonies located near freshwater systems with abundant riparian vegetation have been reported in Uruguay. This odd phenomenon, known as "River disease" by beekeepers, can lead to colony death by depopulation. The aim of this study was to detect the causes of larvae death. Different experiments and analyses were performed using affected apiaries located between two important water courses. 1 day old larvae were the most susceptible and substances that killed the larvae were present in the nectar but not in the pollen. A palynological analysis of nectar samples showed that bees collect this resource from commonly pollinated floral species in the country. However, abundant fungi spores and conidia were found, which indicates that the bees also collected honeydews. In the riparian vegetation, bees were observed collecting the secretions of the planthopper Epormenis cestri on Sebastiania schottiana trees. It was found that the mortality period of larvae overlaps with the presence of E. cestri. Larvae maintained in the laboratory were fed (i) nectar from healthy colonies, (ii) nectar from affected colonies, and (iii) secretions of E. cestri. The mortality of the larvae that received nectar from colonies affected with River disease and secretions of E. cestri was higher than the mortality of those receiving nectar from healthy colonies. This represents the first report of planthopper honeydew causing mass larval mortality in honey bees.
[Mh] Termos MeSH primário: Colapso da Colônia
Euphorbiaceae/química
Insetos/metabolismo
Larva
[Mh] Termos MeSH secundário: Animais
Uruguai
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180221
[Lr] Data última revisão:
180221
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180110
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0190697


  2 / 96 MEDLINE  
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[PMID]:28715431
[Au] Autor:vanEngelsdorp D; Traynor KS; Andree M; Lichtenberg EM; Chen Y; Saegerman C; Cox-Foster DL
[Ad] Endereço:Department of Entomology, Plant Science Building University of Maryland, College Park, Maryland, United States of America.
[Ti] Título:Colony Collapse Disorder (CCD) and bee age impact honey bee pathophysiology.
[So] Source:PLoS One;12(7):e0179535, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Honey bee (Apis mellifera) colonies continue to experience high annual losses that remain poorly explained. Numerous interacting factors have been linked to colony declines. Understanding the pathways linking pathophysiology with symptoms is an important step in understanding the mechanisms of disease. In this study we examined the specific pathologies associated with honey bees collected from colonies suffering from Colony Collapse Disorder (CCD) and compared these with bees collected from apparently healthy colonies. We identified a set of pathological physical characteristics that occurred at different rates in CCD diagnosed colonies prior to their collapse: rectum distension, Malpighian tubule iridescence, fecal matter consistency, rectal enteroliths (hard concretions), and venom sac color. The multiple differences in rectum symptomology in bees from CCD apiaries and colonies suggest effected bees had trouble regulating water. To ensure that pathologies we found associated with CCD were indeed pathologies and not due to normal changes in physical appearances that occur as an adult bee ages (CCD colonies are assumed to be composed mostly of young bees), we documented the changes in bees of different ages taken from healthy colonies. We found that young bees had much greater incidences of white nodules than older cohorts. Prevalent in newly-emerged bees, these white nodules or cellular encapsulations indicate an active immune response. Comparing the two sets of characteristics, we determined a subset of pathologies that reliably predict CCD status rather than bee age (fecal matter consistency, rectal distension size, rectal enteroliths and Malpighian tubule iridescence) and that may serve as biomarkers for colony health. In addition, these pathologies suggest that CCD bees are experiencing disrupted excretory physiology. Our identification of these symptoms is an important first step in understanding the physiological pathways that underlie CCD and factors impacting bee health.
[Mh] Termos MeSH primário: Envelhecimento
Abelhas/fisiologia
Colapso da Colônia
[Mh] Termos MeSH secundário: Animais
Biomarcadores
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Biomarkers)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170926
[Lr] Data última revisão:
170926
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170718
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0179535


  3 / 96 MEDLINE  
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[PMID]:28570608
[Au] Autor:Jiggins FM
[Ad] Endereço:Department of Genetics, University of Cambridge, Cambridge, United Kingdom.
[Ti] Título:The spread of Wolbachia through mosquito populations.
[So] Source:PLoS Biol;15(6):e2002780, 2017 Jun.
[Is] ISSN:1545-7885
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:In many regions of the world, mosquito-borne viruses pose a growing threat to human health. As an alternative to traditional control measures, the bacterial symbiont Wolbachia has been transferred from Drosophila into the mosquito Aedes aegypti, where it can block the transmission of dengue and Zika viruses. A recent paper has reported large-scale releases of Wolbachia-infected Ae. aegypti in the city of Cairns, Australia. Wolbachia, which is maternally transmitted, invaded and spread through the populations due to a sperm-egg incompatibility called cytoplasmic incompatibility. Over a period of 2 years, a wave of Wolbachia infection slowly spread out from 2 release sites, demonstrating that it will be possible to deploy this strategy in large urban areas. In line with theoretical predictions, Wolbachia infection at a third, smaller release site collapsed due to the immigration of Wolbachia-free mosquitoes from surrounding areas. This remarkable field experiment has both validated theoretical models of Wolbachia population dynamics and demonstrated that this is a viable strategy to modify mosquito populations.
[Mh] Termos MeSH primário: Aedes/microbiologia
Agentes de Controle Biológico/imunologia
Saúde Global
Mosquitos Vetores/microbiologia
Simbiose
Wolbachia/imunologia
[Mh] Termos MeSH secundário: Aedes/crescimento & desenvolvimento
Aedes/imunologia
Aedes/virologia
Distribuição Animal
Animais
Agentes de Controle Biológico/efeitos adversos
Agentes de Controle Biológico/isolamento & purificação
California
Colapso da Colônia
Dengue/prevenção & controle
Dengue/transmissão
Drosophila simulans/crescimento & desenvolvimento
Drosophila simulans/imunologia
Drosophila simulans/microbiologia
Feminino
Seres Humanos
Masculino
Mosquitos Vetores/imunologia
Mosquitos Vetores/virologia
Queensland
Infecções por Rickettsiaceae/imunologia
Infecções por Rickettsiaceae/microbiologia
Infecções por Rickettsiaceae/transmissão
Wolbachia/crescimento & desenvolvimento
Wolbachia/isolamento & purificação
Wolbachia/patogenicidade
Infecção pelo Zika virus/prevenção & controle
Infecção pelo Zika virus/transmissão
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Biological Control Agents)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170926
[Lr] Data última revisão:
170926
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170602
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pbio.2002780


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[PMID]:28557993
[Au] Autor:Schmidt TL; Barton NH; Rasic G; Turley AP; Montgomery BL; Iturbe-Ormaetxe I; Cook PE; Ryan PA; Ritchie SA; Hoffmann AA; O'Neill SL; Turelli M
[Ad] Endereço:School of BioSciences, Bio21 Institute, University of Melbourne, Parkville, Victoria, Australia.
[Ti] Título:Local introduction and heterogeneous spatial spread of dengue-suppressing Wolbachia through an urban population of Aedes aegypti.
[So] Source:PLoS Biol;15(5):e2001894, 2017 May.
[Is] ISSN:1545-7885
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Dengue-suppressing Wolbachia strains are promising tools for arbovirus control, particularly as they have the potential to self-spread following local introductions. To test this, we followed the frequency of the transinfected Wolbachia strain wMel through Ae. aegypti in Cairns, Australia, following releases at 3 nonisolated locations within the city in early 2013. Spatial spread was analysed graphically using interpolation and by fitting a statistical model describing the position and width of the wave. For the larger 2 of the 3 releases (covering 0.97 km2 and 0.52 km2), we observed slow but steady spatial spread, at about 100-200 m per year, roughly consistent with theoretical predictions. In contrast, the smallest release (0.11 km2) produced erratic temporal and spatial dynamics, with little evidence of spread after 2 years. This is consistent with the prediction concerning fitness-decreasing Wolbachia transinfections that a minimum release area is needed to achieve stable local establishment and spread in continuous habitats. Our graphical and likelihood analyses produced broadly consistent estimates of wave speed and wave width. Spread at all sites was spatially heterogeneous, suggesting that environmental heterogeneity will affect large-scale Wolbachia transformations of urban mosquito populations. The persistence and spread of Wolbachia in release areas meeting minimum area requirements indicates the promise of successful large-scale population transformation.
[Mh] Termos MeSH primário: Aedes/microbiologia
Agentes de Controle Biológico
Vírus da Dengue/fisiologia
Dengue/prevenção & controle
Modelos Biológicos
Urbanização
Wolbachia/fisiologia
[Mh] Termos MeSH secundário: Aedes/crescimento & desenvolvimento
Aedes/fisiologia
Aedes/virologia
Animais
Agentes de Controle Biológico/isolamento & purificação
Colapso da Colônia/microbiologia
Colapso da Colônia/virologia
Heurística Computacional
Dengue/transmissão
Dengue/virologia
Vírus da Dengue/crescimento & desenvolvimento
Vírus da Dengue/isolamento & purificação
Vetores de Doenças
Feminino
Saúde Global
Transição Epidemiológica
Seres Humanos
Controle de Infecções
Masculino
Parques Recreativos
Queensland
Análise Espaço-Temporal
Wolbachia/crescimento & desenvolvimento
Wolbachia/isolamento & purificação
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Biological Control Agents)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170906
[Lr] Data última revisão:
170906
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170531
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pbio.2001894


  5 / 96 MEDLINE  
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[PMID]:28403242
[Au] Autor:Wu JL; Zhou CX; Wu PJ; Xu J; Guo YQ; Xue F; Getachew A; Xu SF
[Ad] Endereço:Key Laboratory of Pollinating Insect Biology, Ministry of Agriculture, Institute of Apicultural Research, Chinese Academy of Agricultural Sciences, Beijing, China.
[Ti] Título:Brain metabolomic profiling of eastern honey bee (Apis cerana) infested with the mite Varroa destructor.
[So] Source:PLoS One;12(4):e0175573, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The mite Varroa destructor is currently the greatest threat to apiculture as it is causing a global decrease in honey bee colonies. However, it rarely causes serious damage to its native hosts, the eastern honey bees Apis cerana. To better understand the mechanism of resistance of A. cerana against the V. destructor mite, we profiled the metabolic changes that occur in the honey bee brain during V. destructor infestation. Brain samples were collected from infested and control honey bees and then measured using an untargeted liquid chromatography-tandem mass spectrometry (LC-MS/MS)-based global metabolomics method, in which 7918 and 7462 ions in ESI+ and ESI- mode, respectively, were successfully identified. Multivariate statistical analyses were applied, and 64 dysregulated metabolites, including fatty acids, amino acids, carboxylic acid, and phospholipids, amongst others, were identified. Pathway analysis further revealed that linoleic acid metabolism; propanoate metabolism; and glycine, serine, and threonine metabolism were acutely perturbed. The data obtained in this study offer insight into the defense mechanisms of A. cerana against V. destructor mites and provide a better method for understanding the synergistic effects of parasitism on honey bee colonies.
[Mh] Termos MeSH primário: Abelhas/metabolismo
Encéfalo/metabolismo
Varroidae/fisiologia
[Mh] Termos MeSH secundário: Animais
Abelhas/parasitologia
Colapso da Colônia/parasitologia
Resistência à Doença
Asseio Animal
Interações Hospedeiro-Parasita
Redes e Vias Metabólicas
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170504
[Lr] Data última revisão:
170504
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170414
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0175573


  6 / 96 MEDLINE  
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[PMID]:28135666
[Au] Autor:Dance C; Botías C; Goulson D
[Ad] Endereço:School of Life Sciences, University of Sussex, Falmer, Brighton BN1 9QG, United Kingdom.
[Ti] Título:The combined effects of a monotonous diet and exposure to thiamethoxam on the performance of bumblebee micro-colonies.
[So] Source:Ecotoxicol Environ Saf;139:194-201, 2017 May.
[Is] ISSN:1090-2414
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:There is a pressing need to better understand the factors contributing to declines of wild pollinators such as bumblebees. Many different contributors have been postulated including: loss of flower-rich habitats and nesting sites; monotonous diets; impacts of invasive pathogens; exposure to pesticides such as neonicotinoids. Past research has tended to investigate the impacts of these stressors in isolation, despite the increasing recognition that bees are simultaneously exposed to a combination of stressors, with potentially additive or synergistic effects. No studies to date have investigated the combined effects of a monotonous diet and exposure to pesticides. Using queenless micro-colonies of Bombus terrestris audax, we examined this interaction by providing bees with monofloral or polyfloral pollen that was either contaminated with field-realistic levels of thiamethoxam, a commonly used neonicotinoid, or not contaminated. Both treatments were found to have a significant effect on various parameters relating to micro-colony performance. Specifically, both pesticide-treated micro-colonies and those fed monofloral pollen grew more slowly than those given polyfloral pollen or pollen without pesticides. The two factors appeared to act additively. Micro-colonies given monofloral pollens also exhibited lower reproductive efforts and produced smaller drones. Although further research is needed to examine whether similar effects are found in whole colonies, these findings increase our understanding of the likely effects of multiple stressors associated with agricultural intensification on bee declines.
[Mh] Termos MeSH primário: Abelhas/efeitos dos fármacos
Abelhas/crescimento & desenvolvimento
Dieta/efeitos adversos
Inseticidas/toxicidade
Nitrocompostos/toxicidade
Oxazinas/toxicidade
Tiazóis/toxicidade
[Mh] Termos MeSH secundário: Animais
Colapso da Colônia
Feminino
Masculino
Neonicotinoides
Pólen/química
Reprodução
Estresse Fisiológico
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Insecticides); 0 (Neonicotinoids); 0 (Nitro Compounds); 0 (Oxazines); 0 (Thiazoles); 747IC8B487 (thiamethoxam)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170131
[St] Status:MEDLINE


  7 / 96 MEDLINE  
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[PMID]:28088343
[Au] Autor:Shanks JL; Haigh AM; Riegler M; Spooner-Hart RN
[Ad] Endereço:School of Science and Health, Western Sydney University, Locked Bag 1797, Penrith, NSW 2751, Australia; Plant Health Australia, Phipps Close, Deakin, ACT 2600, Australia.
[Ti] Título:First confirmed report of a bacterial brood disease in stingless bees.
[So] Source:J Invertebr Pathol;144:7-10, 2017 Mar.
[Is] ISSN:1096-0805
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Susceptibility to brood pathogens in eusocial stingless bees (Meliponini), alternative pollinators to honey bees, is unknown. Brood losses in managed colonies of the Australian stingless bee, Tetragonula carbonaria, were studied over 20months. We isolated a disease-causing bacterium, Lysinibacillus sphaericus (Firmicutes, Bacillaceae), from worker and queen larvae, brood cell provisions and honey stores. Pathogenicity experiments confirmed this bacterium as the causal organism. It took 22days from infection to first appearance of brood disease symptoms. This is the first confirmed record of a brood pathogen in stingless bees.
[Mh] Termos MeSH primário: Abelhas/microbiologia
Colapso da Colônia/microbiologia
[Mh] Termos MeSH secundário: Animais
Austrália
Firmicutes
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171002
[Lr] Data última revisão:
171002
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170116
[St] Status:MEDLINE


  8 / 96 MEDLINE  
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Blochtein, Betina
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[PMID]:27887862
[Au] Autor:Díaz S; de Souza Urbano S; Caesar L; Blochtein B; Sattler A; Zuge V; Haag KL
[Ad] Endereço:Programa de Pós-Graduação em Genética e Biologia Molecular, Universidade Federal do Rio Grande do Sul, Av. Bento Gonçalves 9500, CEP 91501-970 Porto Alegre, RS, Brazil.
[Ti] Título:Report on the microbiota of Melipona quadrifasciata affected by a recurrent disease.
[So] Source:J Invertebr Pathol;143:35-39, 2017 Feb.
[Is] ISSN:1096-0805
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Melipona quadrifasciata is an eusocial stingless bee traditionally used for honey production in Brazil. In the last decades, the species disappeared from the wild in Southern Brazil, being kept exclusively in managed colonies for commercial and recreational purposes. Stingless beekeepers from this region report annual losses of their colonies due to a syndrome of yet unknown causes. We investigate whether it is associated to pathogenic microorganisms already known to cause disease in bees. These results provide a starting point for future studies aimed at clarifying the relationship between the microbial community of stingless bees and their colony collapses.
[Mh] Termos MeSH primário: Infecções Bacterianas/veterinária
Abelhas/microbiologia
Colapso da Colônia/microbiologia
[Mh] Termos MeSH secundário: Animais
Brasil
RNA Bacteriano/análise
RNA Ribossômico 16S/análise
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (RNA, Bacterial); 0 (RNA, Ribosomal, 16S)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:171118
[Lr] Data última revisão:
171118
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161127
[St] Status:MEDLINE


  9 / 96 MEDLINE  
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[PMID]:27517641
[Au] Autor:Thorbek P; Campbell PJ; Thompson HM
[Ad] Endereço:Jealott's Hill International Research Centre, Syngenta, Bracknell, United Kingdom.
[Ti] Título:Colony impact of pesticide-induced sublethal effects on honeybee workers: A simulation study using BEEHAVE.
[So] Source:Environ Toxicol Chem;36(3):831-840, 2017 Mar.
[Is] ISSN:1552-8618
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Research on neonicotinoids and honeybees have changed focus from direct mortality to sublethal effects. In the present study, a published honeybee model, BEEHAVE, is used to compare induced colony level impact of pesticides including direct mortality, poor brood care, disorientation, and increased handling time in oilseed rape and sunflower crops. Actual effects on individual bees will depend on exposure concentrations, but in the present study large effects were enforced. In oilseed rape, poor brood care had the largest colony impact, because it created a bottleneck for spring build-up of the workforce, and colony impact for all effect types peaked 1 mo after exposure ceased. In sunflower, the later exposure changed the response so colony impact peaked during exposure, and the bottleneck was honey store build-up. In all scenarios, good forage mitigated effects substantially. It is concluded that field studies should continue at least 1 mo after exposure to ensure detection of ecologically relevant sublethal effects. The results indicated that even if a sublethal effect is difficult to detect in the field, subsequent ecologically relevant colony level impacts would be clear if studies are continued for 1 mo after exposure. Guidance for regulatory studies recommends extended observation periods, and published field studies already use extended observation periods, so it is concluded that current methods are adequate for detecting ecologically relevant sublethal effects. Although published laboratory and semifield studies conducted under controlled exposure conditions suggest that sublethal effects may occur, published field studies with neonicotinoid seed treatments, naturally foraging bees, and extended observation periods do not report colony-level effects, suggesting that in these studies no ecologically relevant sublethal effects occurred. Environ Toxicol Chem 2017;36:831-840. © 2016 SETAC.
[Mh] Termos MeSH primário: Abelhas/efeitos dos fármacos
Colapso da Colônia/induzido quimicamente
Poluentes Ambientais/toxicidade
Modelos Teóricos
Praguicidas/toxicidade
[Mh] Termos MeSH secundário: Animais
Abelhas/fisiologia
Comportamento Animal/efeitos dos fármacos
Brassica napus/crescimento & desenvolvimento
Produtos Agrícolas/crescimento & desenvolvimento
Relação Dose-Resposta a Droga
Helianthus/crescimento & desenvolvimento
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Environmental Pollutants); 0 (Pesticides)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170717
[Lr] Data última revisão:
170717
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160813
[St] Status:MEDLINE
[do] DOI:10.1002/etc.3581


  10 / 96 MEDLINE  
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[PMID]:27197805
[Au] Autor:Koo JE; Kim KJ; Park HW; Kim HK; Choe JW; Chang HS; Lee JY; Myung SJ; Yang SK; Kim JH
[Ad] Endereço:Health Screening and Promotion Center, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
[Ti] Título:Prevalence and risk factors of advanced colorectal neoplasms in asymptomatic Korean people between 40 and 49 years of age.
[So] Source:J Gastroenterol Hepatol;32(1):98-105, 2017 Jan.
[Is] ISSN:1440-1746
[Cp] País de publicação:Australia
[La] Idioma:eng
[Ab] Resumo:BACKGROUND AND AIM: Current guidelines recommend colon cancer screening for persons aged over 50 years. However, there are few data on colorectal cancer screening in 40- to 49-year-olds. This study assessed the prevalence and risk factors of colorectal neoplasms in 40- to 49-year-old Koreans. METHODS: We analyzed the results of screening colonoscopies of 6680 persons 40-59 years of age (2206 aged 40-49 and 4474 aged 50-59 years). RESULTS: The prevalence of overall and advanced neoplasms in the 40- to 49-year age group was lower than in the 50- to 59-year age group (26.7% and 2.4% vs 37.8% and 3.5%, respectively). However, the prevalence of overall and advanced neoplasms increased to 39.1% and 5.4%, respectively, in 45- to 49-year-old individuals with metabolic syndrome. In the 40- to 49-year age group, age, current smoking, and metabolic syndrome were associated with an increased risk of advanced neoplasms (odds ratio [OR] 1.16, 95% confidence interval [CI] 1.04-1.30; OR 3.12, 95% CI 1.20-8.12; and OR 2.00, 95% CI 1.09-3.67, respectively). CONCLUSIONS: Individuals aged 40-49 years had a lower prevalence of colorectal neoplasms than those aged 50-59 years, but some 40- to 49-year-olds showed a similar prevalence to those aged 50-59 years. Age, current smoking habits, and metabolic syndrome are associated with an increased risk of advanced neoplasms in subjects aged 40-49 years. Further studies are needed to stratify the risks of colon cancer and guide targeted screening in persons younger than 50 years old.
[Mh] Termos MeSH primário: Neoplasias Colorretais/epidemiologia
[Mh] Termos MeSH secundário: Adulto
Distribuição por Idade
Grupo com Ancestrais do Continente Asiático
Colapso da Colônia
Neoplasias Colorretais/etiologia
Neoplasias Colorretais/prevenção & controle
Feminino
Seres Humanos
Masculino
Programas de Rastreamento
Síndrome Metabólica
Meia-Idade
Prevalência
República da Coreia/epidemiologia
Fatores de Risco
Fumar
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1707
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160521
[St] Status:MEDLINE
[do] DOI:10.1111/jgh.13454



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BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde