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[PMID]: 29346418 [Au] Autor: Collaco JM; Appel LJ; McGready J; Cutting GR [Ad] Endereço: Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America. [Ti] Título: The relationship of lung function with ambient temperature. [So] Source: PLoS One;13(1):e0191409, 2018. [Is] ISSN: 1932-6203 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: BACKGROUND: Lung function is complex trait with both genetic and environmental factors contributing to variation. It is unknown how geographic factors such as climate affect population respiratory health. OBJECTIVE: To determine whether ambient air temperature is associated with lung function (FEV1) in the general population. DESIGN/SETTING: Associations between spirometry data from two National Health and Nutrition Examination Survey (NHANES) periods representative of the U.S. non-institutionalized population and mean annual ambient temperature were assessed using survey-weighted multivariate regression. PARTICIPANTS/MEASUREMENTS: The NHANES III (1988-94) cohort included 14,088 individuals (55.6% female) and the NHANES 2007-12 cohort included 14,036 individuals (52.3% female), with mean ages of 37.4±23.4 and 34.4±21.8 years old and FEV1 percent predicted values of 99.8±15.8% and 99.2±14.5%, respectively. RESULTS: After adjustment for confounders, warmer ambient temperatures were associated with lower lung function in both cohorts (NHANES III p = 0.020; NHANES 2007-2012 p = 0.014). The effect was similar in both cohorts with a 0.71% and 0.59% predicted FEV1 decrease for every 10°F increase in mean temperature in the NHANES III and NHANES 2007-2012 cohorts, respectively. This corresponds to ~2 percent predicted difference in FEV1 between the warmest and coldest regions in the continental United States. CONCLUSIONS: In the general U.S. population, residing in regions with warmer ambient air temperatures was associated with lower lung function with an effect size similar to that of traffic pollution. Rising temperatures associated with climate change could have effects on pulmonary function in the general population. [Mh] Termos MeSH primário: Ar Volume Expiratório Forçado Temperatura Ambiente [Mh] Termos MeSH secundário: Adulto Estudos de Coortes Fatores de Confusão (Epidemiologia) Feminino Seres Humanos Masculino [Pt] Tipo de publicação: JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL [Em] Mês de entrada: 1803 [Cu] Atualização por classe: 180309 [Lr] Data última revisão: 180309 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 180119 [St] Status: MEDLINE [do] DOI: 10.1371/journal.pone.0191409

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[PMID]: 29193666 [Au] Autor: Fraser C; Jackson S [Ad] Endereço: Lorax Environmental Services, Vancouver, British Columbia, Canada. [Ti] Título: Shifts in air temperature and high-magnitude winter precipitation events in coastal North America: Implications for Environmental Assessment and Management. [So] Source: Integr Environ Assess Manag;14(2):185-188, 2018 Mar. [Is] ISSN: 1551-3793 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: This commentary examines recent shifts in air temperature data coinciding with high-magnitude precipitation events at climate stations spanning an elevational and longitudinal gradient on the south coast of British Columbia, Canada. Results presented show that high-magnitude winter precipitation events are occurring on British Columbia's south coast under progressively warmer conditions. In the future, proportionally more winter precipitation is anticipated to report as rainfall versus snow, and over time these changes will have a marked impact on the snowmelt-dominated hydrographs that characterize local watersheds. Robust preparedness strategies will be needed to balance competing interests such as the security of domestic water supplies, the permitting and operation of major projects (e.g., mines, hydrodevelopments), and the achievement of broader ecosystem health goals under these changing hydroclimatic conditions. Integr Environ Assess Manag 2018;14:185-188. © 2018 SETAC. [Mh] Termos MeSH primário: Ar/análise Monitoramento Ambiental Temperatura Ambiente [Mh] Termos MeSH secundário: Colúmbia Britânica Conservação dos Recursos Naturais Estações do Ano [Pt] Tipo de publicação: JOURNAL ARTICLE [Em] Mês de entrada: 1803 [Cu] Atualização por classe: 180308 [Lr] Data última revisão: 180308 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 171202 [St] Status: MEDLINE [do] DOI: 10.1002/ieam.2012

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[PMID]: 29390305 [Au] Autor: Hwang SH; Yoo C; Kim YY; Lee DY; Nam DH; Lee JY [Ad] Endereço: Department of Ophthalmology, Gachon University, College of Medicine Gil Medical Center, Incheon. [Ti] Título: Intracameral air injection during Ahmed glaucoma valve implantation in neovascular glaucoma for the prevention of tube obstruction with blood clot: Case Report. [So] Source: Medicine (Baltimore);96(50):e9092, 2017 Dec. [Is] ISSN: 1536-5964 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: RATIONALE: Glaucoma drainage implant surgery is a treatment option for the management of neovascular glaucoma. However, tube obstruction by blood clot after Ahmed glaucoma valve (AGV) implantation is an unpredictable clinically challenging situation. PATIENT CONCERNS-DIAGNOSES-INTERVENTIONS: We report 4 cases using intracameral air injection for the prevention of the tube obstruction of AGV by blood clot. OUTCOMES: The first case was a 57-year-old female suffering from ocular pain because of a tube obstruction with blood clot after AGV implantation in neovascular glaucoma. Surgical blood clot removal was performed. However, intractable bleeding was noted during the removal of the blood clot, and so intracameral air injection was performed to prevent a recurrent tube obstruction. After the procedure, although blood clots formed around the tube, the tube opening where air could touch remained patent. In 3 cases of neovascular glaucoma with preoperative severe intraocular hemorrhages, intracameral air injection and AGV implantation were performed simultaneously. In all 3 cases, tube openings were patent. It appears that air impeded the blood clots formation in front of the tube opening. LESSONS: Intracameral air injection could be a feasible option to prevent tube obstruction of AGV implant with a blood clot in neovascular glaucoma with high risk of tube obstruction. [Mh] Termos MeSH primário: Ar Implantes para Drenagem de Glaucoma Glaucoma Neovascular/cirurgia Complicações Pós-Operatórias/prevenção & controle Trombose/prevenção & controle [Mh] Termos MeSH secundário: Adulto Feminino Seres Humanos Injeções Masculino Meia-Idade Estudos Retrospectivos [Pt] Tipo de publicação: CASE REPORTS; JOURNAL ARTICLE [Em] Mês de entrada: 1802 [Cu] Atualização por classe: 180301 [Lr] Data última revisão: 180301 [Sb] Subgrupo de revista: AIM; IM [Da] Data de entrada para processamento: 180203 [St] Status: MEDLINE [do] DOI: 10.1097/MD.0000000000009092

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[PMID]: 29292809 [Au] Autor: Tascini AS; Noro MG; Chen R; Seddon JM; Bresme F [Ad] Endereço: Department of Chemistry, Imperial College London, UK. ast14@ic.ac.uk fbresme@imperial.ac.uk. [Ti] Título: Understanding the interactions between sebum triglycerides and water: a molecular dynamics simulation study. [So] Source: Phys Chem Chem Phys;20(3):1848-1860, 2018 Jan 17. [Is] ISSN: 1463-9084 [Cp] País de publicação: England [La] Idioma: eng [Ab] Resumo: In recent years, sebum oil has been found to play a key role in the regulation of the hydration of the outermost layer of the skin, the stratum corneum. Understanding how a major component of the sebum oil, the triglyceride tri-cis-6-hexadecenoin (TG), interacts with water is an important step in gaining insight into the water regulation function of the sebum oil. Here we use molecular dynamics simulations to investigate the structural and interfacial properties of TG in bulk and at the air and water interface. Our model performs very well in reproducing experimental results, such as density, surface tensions and surface pressure area isotherms. We show that triglyceride molecules in the liquid phase assemble together, through the glycerol group, forming a single percolating network. TG-air interfaces orient the lipids with the interface enriched with the hydrophobic tails and the glycerol groups buried inside. When in contact with water, the TG molecules at the interface orient the glycerol group towards the water phase and adopt a characteristic trident conformation. Water is shown to penetrate the TG layer thanks to the interaction with the oxygen atoms of the TG molecules, which acts as a pathway for water diffusion. The activation energy for the passage of water is found to be ≈9.5k T at 310 K, showing that the layer is permeable to water diffusion. [Mh] Termos MeSH primário: Simulação de Dinâmica Molecular Sebo/metabolismo Triglicerídeos/química Água/química [Mh] Termos MeSH secundário: Ar Seres Humanos Propriedades de Superfície Tensão Superficial [Pt] Tipo de publicação: JOURNAL ARTICLE [Nm] Nome de substância: 0 (Triglycerides); 059QF0KO0R (Water) [Em] Mês de entrada: 1802 [Cu] Atualização por classe: 180220 [Lr] Data última revisão: 180220 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 180103 [St] Status: MEDLINE [do] DOI: 10.1039/c7cp06889a

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[PMID]: 28742620 [Au] Autor: Ampazas P; Droutsas K; Giallouros E; Schroeder FM; Sekundo W [Ad] Endereço: *Department of Ophthalmology, Philipps University of Marburg, Marburg, Germany; and †First Department of Ophthalmology, National and Kapodistrian University of Athens-Faculty of Medicine, Athens, Greece. [Ti] Título: Comparison of 5% Sulfur Hexafluoride Versus 100% Air Tamponade in Descemet Membrane Endothelial Keratoplasty. [So] Source: Cornea;36(10):1189-1194, 2017 Oct. [Is] ISSN: 1536-4798 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: PURPOSE: To compare the rebubbling rate and clinical outcomes of Descemet membrane endothelial keratoplasty (DMEK) with 5% sulfur hexafluoride (SF6) gas versus 100% air as a tamponade for graft attachment. METHODS: Retrospective, comparative, interventional case series including 368 consecutive pseudophakic eyes with Fuchs endothelial dystrophy or pseudophakic bullous keratopathy that underwent DMEK in a tertiary referral center between October 2010 and August 2015 using either air (group 1, 191 eyes) or 5% SF6 (group 2, 177 eyes) as a tamponade. The rebubbling rate, complications, best-corrected distance visual acuity (BCVA), manifest refraction, and endothelial cell density were analyzed before and at 1 week, 1, 3, 6, 12, 24, and 36 months after surgery. RESULTS: The rebubbling rate was 20.4% (39/191, group 1) versus 6.8% (12/177, group 2; P < 0.001). Complications included cystoid macular edema (n = 5, group 1, and n = 10, group 2; P = 0.14) and 1 case of presumed allograft rejection (n = 1, group 2). The follow-up period was 12 ± 8 months for group 1 and 6 ± 4 months for group 2. BCVA (logarithm of the minimum angle of resolution) had improved after 12 months from 1.43 ± 0.63 to 0.18 ± 0.26 (group 1, P < 0.001) and from 1.8 ± 0.63 to 0.18 ± 0.17 (group 2, P < 0.001). The percentage of eyes with BCVA ≥0.2 logarithm of the minimum angle of resolution at 12 months was 70.9% (90/127, group 1) and 78.4% (40/51, group 2; P = 0.3). Endothelial cell loss at 12 months after DMEK was 44 ± 18% (group 1) versus 33 ± 15% (group 2, P = 0.07). CONCLUSIONS: The use of a tamponade with 5% SF6 yielded a significantly lower incidence of graft detachment requiring surgical reintervention with no detrimental effect on graft endothelial cells. Thus, routine use of 5% SF6 for a graft tamponade in DMEK is recommended. [Mh] Termos MeSH primário: Ar Perda de Células Endoteliais da Córnea/prevenção & controle Ceratoplastia Endotelial com Remoção da Lâmina Limitante Posterior Tamponamento Interno/métodos Rejeição de Enxerto/prevenção & controle Hexafluoreto de Enxofre/administração & dosagem Aderências Teciduais [Mh] Termos MeSH secundário: Idoso Contagem de Células Feminino Distrofia Endotelial de Fuchs/cirurgia Seres Humanos Masculino Refração Ocular/fisiologia Estudos Retrospectivos Doadores de Tecidos Acuidade Visual/fisiologia [Pt] Tipo de publicação: COMPARATIVE STUDY; JOURNAL ARTICLE [Nm] Nome de substância: WS7LR3I1D6 (Sulfur Hexafluoride) [Em] Mês de entrada: 1802 [Cu] Atualização por classe: 180209 [Lr] Data última revisão: 180209 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170726 [St] Status: MEDLINE [do] DOI: 10.1097/ICO.0000000000001299

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[PMID]: 29323902 [Au] Autor: Cai B; Saito A; Ikeda S [Ad] Endereço: Department of Food Science and ‡Department of Chemistry, University of Wisconsin-Madison , Madison, Wisconsin 53706, United States. [Ti] Título: Maillard Conjugation of Sodium Alginate to Whey Protein for Enhanced Resistance to Surfactant-Induced Competitive Displacement from Air-Water Interfaces. [So] Source: J Agric Food Chem;66(3):704-710, 2018 Jan 24. [Is] ISSN: 1520-5118 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: Whey protein adsorbed to an interface forms a viscoelastic interfacial film but is displaced competitively from the interface by a small-molecule surfactant added afterward. The present study evaluated the impact of the covalent conjugation of high- or low-molecular-weight sodium alginate (HA or LA) to whey protein isolate (WPI) via the Maillard reaction on the ability of whey protein to resist surfactant-induced competitive displacement from the air-water interface. Surfactant added after the pre-adsorption of conjugate to the interface increased surface pressure. At a given surface pressure, the WPI-LA conjugate showed a significantly higher interfacial area coverage and lower interfacial film thickness compared to those of the WPI-HA conjugate or unconjugated WPI. The addition of LA to the aqueous phase had little effect on the interfacial area and thickness of pre-adsorbed WPI. These results suggest the importance of the molecular weight of the polysaccharide moiety in determining interfacial properties of whey protein-alginate conjugates. [Mh] Termos MeSH primário: Alginatos/química Tensoativos/química Proteínas do Soro do Leite/química [Mh] Termos MeSH secundário: Ar/análise Ácido Glucurônico/química Ácidos Hexurônicos/química Reação de Maillard Peso Molecular Água/química [Pt] Tipo de publicação: JOURNAL ARTICLE [Nm] Nome de substância: 0 (Alginates); 0 (Hexuronic Acids); 0 (Surface-Active Agents); 0 (Whey Proteins); 059QF0KO0R (Water); 8A5D83Q4RW (Glucuronic Acid); 8C3Z4148WZ (alginic acid) [Em] Mês de entrada: 1802 [Cu] Atualização por classe: 180207 [Lr] Data última revisão: 180207 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 180112 [St] Status: MEDLINE [do] DOI: 10.1021/acs.jafc.7b04387

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[PMID]: 28463224 [Au] Autor: Bluman J; Kang CK [Ad] Endereço: Department of Mechanical and Aerospace Engineering, University of Alabama in Huntsville, Huntsville, AL 35899, United States of America. [Ti] Título: Wing-wake interaction destabilizes hover equilibrium of a flapping insect-scale wing. [So] Source: Bioinspir Biomim;12(4):046004, 2017 06 15. [Is] ISSN: 1748-3190 [Cp] País de publicação: England [La] Idioma: eng [Ab] Resumo: Wing-wake interaction is a characteristic nonlinear flow feature that can enhance unsteady lift in flapping flight. However, the effects of wing-wake interaction on the flight dynamics of hover are inadequately understood. We use a well-validated 2D Navier-Stokes equation solver and a quasi-steady model to investigate the role of wing-wake interaction on the hover stability of a fruit fly scale flapping flyer. The Navier-Stokes equations capture wing-wake interaction, whereas the quasi-steady models do not. Both aerodynamic models are tightly coupled to a flight dynamic model, which includes the effects of wing mass. The flapping amplitude, stroke plane angle, and flapping offset angle are adjusted in free flight for various wing rotations to achieve hover equilibrium. We present stability results for 152 simulations which consider different kinematics involving the pitch amplitude and pitch axis as well as the duration and timing of pitch rotation. The stability of all studied motions was qualitatively similar, with an unstable oscillatory mode present in each case. Wing-wake interaction has a destabilizing effect on the longitudinal stability, which cannot be predicted by a quasi-steady model. Wing-wake interaction increases the tendency of the flapping flyer to pitch up in the presence of a horizontal velocity perturbation, which further destabilizes the unstable oscillatory mode of hovering flight dynamics. [Mh] Termos MeSH primário: Biomimética/instrumentação Dípteros/fisiologia Voo Animal/fisiologia Asas de Animais/fisiologia [Mh] Termos MeSH secundário: Ar Animais Fenômenos Biomecânicos Insetos/fisiologia Modelos Biológicos Fatores de Tempo [Pt] Tipo de publicação: JOURNAL ARTICLE; RESEARCH SUPPORT, U.S. GOV'T, NON-P.H.S.; RESEARCH SUPPORT, NON-U.S. GOV'T [Em] Mês de entrada: 1802 [Cu] Atualização por classe: 180208 [Lr] Data última revisão: 180208 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170503 [St] Status: MEDLINE [do] DOI: 10.1088/1748-3190/aa7085

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[PMID]: 28803160 [Au] Autor: Wang C; Chen Z; Cao W [Ad] Endereço: Condensed Matter Science and Technology, Institute and Department of Physics, Harbin Institute of Technology, Harbin 150080, China; Materials Research Institute, The Pennsylvania State University, University Park, PA 16802, USA. [Ti] Título: Differentiate low impedance media in closed steel tank using ultrasonic wave tunneling. [So] Source: Ultrasonics;82:130-133, 2018 01. [Is] ISSN: 1874-9968 [Cp] País de publicação: Netherlands [La] Idioma: eng [Ab] Resumo: Ultrasonic wave tunneling through seriously mismatched media, such as steel and water, is possible only when the frequency matches the resonance of the steel plate. But it is nearly impossible to realize continuous wave tunneling if the low acoustic impedance media is air because the transducer frequency cannot be made so accurate. The issue might be resolved using tone-burst signals. Using finite element simulations, we found that for air media when the cycle number is 20, the -6dB bandwidth of energy transmission increased from 0.001% to 5.9% compared with that of continuous waves. We show that the tunneling waves can give us enough information to distinguish low acoustic impedance media inside a steel tank. [Mh] Termos MeSH primário: Testes de Impedância Acústica [Mh] Termos MeSH secundário: Ar Análise de Elementos Finitos Aço Transdutores Vibração Água [Pt] Tipo de publicação: JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL; RESEARCH SUPPORT, NON-U.S. GOV'T [Nm] Nome de substância: 059QF0KO0R (Water); 12597-69-2 (Steel) [Em] Mês de entrada: 1801 [Cu] Atualização por classe: 180123 [Lr] Data última revisão: 180123 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170814 [St] Status: MEDLINE

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[PMID]: 28745815 [Au] Autor: Chao D; Zhao M [Ad] Endereço: School of Petroleum and Chemical Engineering, Dalian University of Technology, Panjin, Liaoning, P. R. China. [Ti] Título: Robust Cooperative Photo-oxidation of Sulfides without Sacrificial Reagent under Air Using a Dinuclear Ru -Cu Assembly. [So] Source: ChemSusChem;10(17):3358-3362, 2017 09 11. [Is] ISSN: 1864-564X [Cp] País de publicação: Germany [La] Idioma: eng [Ab] Resumo: A molecular chromophore-catalyst assembly containing a chromophore ruthenium(II) center (RuIIchro ) and a catalytic copper(II) center (CuIIcat ) has been prepared easily. The assembly was employed for photocatalytic oxidation of sulfides without sacrificial reagent in the presence of dioxygen under blue light irradiation. Unprecedented turnover number (TON) up to 32 000 was achieved. It was elucidated that an electron transferred from excited state of chromophore RuII*chro to CuIIcat along with generation of CuIcat that was further activated by O . These results demonstrate a promising strategy for efficient cooperative photocatalytic reactions under air using the chromophore-catalyst assembly. [Mh] Termos MeSH primário: Ar Cobre/química Compostos Organometálicos/química Processos Fotoquímicos Rutênio/química Sulfetos/química [Mh] Termos MeSH secundário: Catálise Oxirredução [Pt] Tipo de publicação: JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T [Nm] Nome de substância: 0 (Organometallic Compounds); 0 (Sulfides); 789U1901C5 (Copper); 7UI0TKC3U5 (Ruthenium) [Em] Mês de entrada: 1709 [Cu] Atualização por classe: 180118 [Lr] Data última revisão: 180118 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170727 [St] Status: MEDLINE [do] DOI: 10.1002/cssc.201700930

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[PMID]: 29236716 [Au] Autor: Ongaro F; Scheggi S; Ghosh A; Denasi A; Gracias DH; Misra S [Ad] Endereço: Surgical Robotics Laboratory, Department of Biomechanical Engineering, University of Twente, 7522 NB Enschede, The Netherlands. [Ti] Título: Design, characterization and control of thermally-responsive and magnetically-actuated micro-grippers at the air-water interface. [So] Source: PLoS One;12(12):e0187441, 2017. [Is] ISSN: 1932-6203 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: The design and control of untethered microrobotic agents has drawn a lot of attention in recent years. This technology truly possesses the potential to revolutionize the field of minimally invasive surgery and microassembly. However, miniaturization and reliable actuation of micro-fabricated grippers are still challenging at sub-millimeter scale. In this study, we design, manufacture, characterize, and control four similarly-structured semi-rigid thermoresponsive micro-grippers. Furthermore, we develop a closed loop-control algorithm to demonstrate and compare the performance of the said grippers when moving in hard-to-reach and unpredictable environments. Finally, we analyze the grasping characteristics of three of the presented designs. Overall, not only does the study demonstrate motion control in unstructured dynamic environments-at velocities up to 3.4, 2.9, 3.3, and 1 body-lengths/s with 980, 750, 250, and 100 µm-sized grippers, respectively-but it also aims to provide quantitative data and considerations to help a targeted design of magnetically-controlled thin micro-grippers. [Mh] Termos MeSH primário: Ar Desenho de Equipamento Magnetismo Robótica/instrumentação Temperatura Ambiente Água [Mh] Termos MeSH secundário: Miniaturização Movimento (Física) [Pt] Tipo de publicação: JOURNAL ARTICLE [Nm] Nome de substância: 059QF0KO0R (Water) [Em] Mês de entrada: 1801 [Cu] Atualização por classe: 180104 [Lr] Data última revisão: 180104 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 171214 [St] Status: MEDLINE [do] DOI: 10.1371/journal.pone.0187441

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