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Pesquisa : G16.500.275.280 [Categoria DeCS]
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[PMID]:29431336
[Au] Autor:Rakhmanin; Ivanova LV; Artemova TZ; Gipp EK; Zagainova AV; Maksimkina TN; Krasnyak AV; Schustova SA; Kuznetsova KY; Aslanova MM; Malysheva AG; Abramov EG; Vodyanova MA; Kamenetsky DB; Aleshnya VV
[Ti] Título:[The importance of sanitary microbiological indices in the evaluation of epidemiological safety of water use in conditions of chemical contamination of water].
[So] Source:Gig Sanit;95(10):934-8, 2016.
[Is] ISSN:0016-9900
[Cp] País de publicação:Russia (Federation)
[La] Idioma:rus
[Ab] Resumo:The increasing chemicalization of production and life leads to the pollution of water bodies by chemicals, the effect of which on the micro - and macro - organisms is poorly understood. This section of the study in sanitary bacteriology is becoming ever more topical and is an important task of modern hygienic science. One of complicacies of the study of the problem is related with the fact that the presence of only experimental data fails to be sufficient, as the impact of any given chemical substance on different bacteria in the experiment does not mean that under natural conditions, similar results will be obtained. One reason for this may be the inhibitory effect of the given chemical on biological properties of bacteria, while in field conditions in the water several chemicals interacting with each other can exist. In this regard, the aim of the work was to assess the indicator value of sanitary and microbiological indices of epidemic hazard of water use in conditions of chemical pollution of surface water bodies.
[Mh] Termos MeSH primário: Bactérias
Monitoramento Ambiental
Água Doce
Microbiologia da Água/normas
Poluição Química da Água
[Mh] Termos MeSH secundário: Bactérias/classificação
Bactérias/efeitos dos fármacos
Bactérias/isolamento & purificação
Bactérias/patogenicidade
Indústria Química/estatística & dados numéricos
Monitoramento Ambiental/métodos
Monitoramento Ambiental/normas
Água Doce/análise
Água Doce/química
Água Doce/microbiologia
Seres Humanos
Moscou/epidemiologia
Saúde Pública/métodos
Saúde Pública/normas
Poluentes Químicos da Água/efeitos adversos
Poluentes Químicos da Água/análise
Poluentes Químicos da Água/classificação
Poluição Química da Água/análise
Poluição Química da Água/prevenção & controle
Abastecimento de Água/normas
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Water Pollutants, Chemical)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180309
[Lr] Data última revisão:
180309
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180213
[St] Status:MEDLINE


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[PMID]:29431316
[Au] Autor:Dementieva DM; Dementiev MS
[Ti] Título:[Premises to the transboundary environmental crisis in the water tract on the example of water tract of the Kuban-Manych].
[So] Source:Gig Sanit;95(9):837-41, 2016.
[Is] ISSN:0016-9900
[Cp] País de publicação:Russia (Federation)
[La] Idioma:rus
[Ab] Resumo:As a result, of the management of the irrigation system the most part of the runoff headwaters of the river Kuban was transferred to the arid plains of the Stavropol Territory, Rostov Region and Kalmykia Gravity Water via the water tract of the Kuban-Manych. This system was assumed to be supplied by pure mountain water. In fact, 3-4 class contaminated water currently passes to the water intake of the irrigation system (Nevinnomyssky channel). There is a tendency to the further deterioration in the quality of surface waters. It was determined that in the last decades in the catchment area of the upper reaches of the Kuban (Karachaevo-Cherkessia) the population was determined to increase sharply. As a result the discharge of industrial, agricultural, domestic and recreational waste into the river significantly increased. In that in catchment areas there is practically no infrastructure of the acquisition, processing and recycling of waste for the irrigation system. Intensive recreational and transport development of mountainous areas of Karachay-Cherkessia aggravates the situation and may lead to the need for deep water purification for subsequent consumption already in the vast territories of the Central Caucasus. Due to lack of the infrastructure for the water treatment in the upper reaches of the Kuban, it can lead to the serious systemic crisis. It is proposed to start to create in the catchment areas the cost-based system of recycling waste on the base of their processing by pyrolysis.
[Mh] Termos MeSH primário: Irrigação Agrícola
Monitoramento Ambiental
Água Doce/análise
Saúde Pública
Rios
Planejamento Social
[Mh] Termos MeSH secundário: Irrigação Agrícola/métodos
Irrigação Agrícola/organização & administração
Irrigação Agrícola/normas
Monitoramento Ambiental/métodos
Monitoramento Ambiental/estatística & dados numéricos
Previsões
Seres Humanos
Dinâmica Populacional/estatística & dados numéricos
Saúde da População/estatística & dados numéricos
Saúde Pública/métodos
Saúde Pública/normas
Federação Russa/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180309
[Lr] Data última revisão:
180309
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180213
[St] Status:MEDLINE


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[PMID]:29431314
[Au] Autor:Baktybaeva ZB; Suleymanov RA; Yamalov SM; Kulagin AA; Valeev TK; Rakhmatullin NR
[Ti] Título:[Evaluation of the content and migration of heavy metals in components of river ecosystems' of mining territories of the Republic of Bashkortostan].
[So] Source:Gig Sanit;95(9):822-7, 2016.
[Is] ISSN:0016-9900
[Cp] País de publicação:Russia (Federation)
[La] Idioma:rus
[Ab] Resumo:Exploration and development of mineral deposits in the Transurals of the Republic of Bashkortostan are accompanied by a comprehensive environmental impact. Ones of the most vulnerable elements of the landscape are the surface water bodies used for fishery purposes, recreation and household needs of the population. Extraction and processing of ores lead to the contamination of aquatic ecosystems by heavy metals (HM), which by passing into a pond, can actively be involved in the cycling of matter and migrate via food chains to the human under the consumption of fish products. Possessing by cumulative properties, HM can express mutagenic, teratogenic and carcinogenic properties. The aim of research was the study of the impact of mining facilities on the content of the priority HM in the components of river ecosystems in the Transurals of the Republic of Bashkortostan and the development of a complex of preventive measures on the improvement of the human environment. There was studied the content of Zn, Cu and Cd in the water, bottom sediments and phytomass of Elodea canadensis Michx. The measurements of mass concentrations of metals were performed by stripping voltammetry with the use of the STA device. The results showed that for the cross-sections there is typical the following descending series of elements in the river components: Zn > Cu > Cd. In water samples there is observed the exceedance of standards for water bodies of potable, cultural and community water use and fishery basins. The concentration of zinc varies in the range of 0.016-5.24 mg/dm; copper - 0.0024-0.095 mg/dm; cadmium - 0.0001-0.019 mg/dm. In bottom sediments, in general, the content of metals in comparison with control plots is increased to the tenfold value. The meaning of mobile forms of zinc in the ground varies in the range of 0.81-9.62 mg/kg; copper - 0.12-18.69 mg/kg; cadmium - 0.00013-0.092 mg/kg. The zinc concentration in above-ground phytomass of Elodea canadensis compared to control increases by 2-3.5 times, copper - 4-8 times, cadmium - 2-7 times. Univariate analysis of variance confirmed the accuracy of the impact of the degree of contamination on the accumulation of metals by Elodea canadensis. The results testify to the potential danger to health of water bodies of the region's population.
[Mh] Termos MeSH primário: Monitorização de Parâmetros Ecológicos
Água Doce
Metais Pesados
Rios/química
Poluição da Água
[Mh] Termos MeSH secundário: Bashkiria/epidemiologia
Monitorização de Parâmetros Ecológicos/métodos
Monitorização de Parâmetros Ecológicos/estatística & dados numéricos
Água Doce/análise
Água Doce/química
Seres Humanos
Hydrocharitaceae/química
Metais Pesados/análise
Metais Pesados/química
Mineração/normas
Saúde da População/estatística & dados numéricos
Saúde Pública/métodos
Saúde Pública/normas
Poluentes Químicos da Água/análise
Poluentes Químicos da Água/química
Poluição da Água/efeitos adversos
Poluição da Água/análise
Poluição da Água/prevenção & controle
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Metals, Heavy); 0 (Water Pollutants, Chemical)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180309
[Lr] Data última revisão:
180309
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180213
[St] Status:MEDLINE


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[PMID]:29228938
[Au] Autor:Nishijima S; Nishikawa C; Miyashita T
[Ad] Endereço:Laboratory of Biodiversity Science, School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo, Tokyo, 113-8657, Japan. nishijimash@gmail.com.
[Ti] Título:Habitat modification by invasive crayfish can facilitate its growth through enhanced food accessibility.
[So] Source:BMC Ecol;17(1):37, 2017 Dec 12.
[Is] ISSN:1472-6785
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Invasive ecosystem engineers can facilitate their invasions by modifying the physical environment to improve their own performance, but this positive feedback process has rarely been tested empirically except in sessile organisms. The invasive crayfish Procambarus clarkii is an ecosystem engineer that destroys aquatic macrophytes, which provide a physical refuge for animal prey, and this destruction is likely to enhance vulnerability to predators. Using two series of mesocosm experiments, we tested the hypothesis that the invasive crayfish increases its feeding efficiency on animal prey by reducing submerged macrophytes, thus increasing its individual growth rate in a positive density-dependent manner. RESULTS: In the first experiment, increasing crayfish density reduced both macrophytes and animal prey (dragonfly and chironomid larvae) and, importantly, increased the growth rate of individual crayfish, in accordance with our expectation. In the second experiment, we used artificial macrophytes to clarify whether the physical architecture of macrophytes itself protects animal prey and limits crayfish growth rate. Increasing the artificial macrophyte quantity not only increased the survival of animal prey, but also retarded the crayfish growth rate. CONCLUSIONS: We conclude that macrophytes strengthen bottom-up control of crayfish, but this effect can be relaxed by increasing the density of crayfish via reduction in macrophytes. This positive feedback process may explain the crayfish outbreaks and regime shifts occasionally observed in invaded freshwater ecosystems.
[Mh] Termos MeSH primário: Astacoidea/fisiologia
Ecossistema
Cadeia Alimentar
Espécies Introduzidas
[Mh] Termos MeSH secundário: Animais
Astacoidea/crescimento & desenvolvimento
Chironomidae/crescimento & desenvolvimento
Comportamento Alimentar
Água Doce
Larva/crescimento & desenvolvimento
Odonatos/crescimento & desenvolvimento
Desenvolvimento Vegetal
Densidade Demográfica
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180309
[Lr] Data última revisão:
180309
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171213
[St] Status:MEDLINE
[do] DOI:10.1186/s12898-017-0147-7


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[PMID]:28934711
[Au] Autor:Colón-Cruz L; Kristofco L; Crooke-Rosado J; Acevedo A; Torrado A; Brooks BW; Sosa MA; Behra M
[Ad] Endereço:Department of Anatomy and Neurobiology, School of Medicine, Medical Sciences Campus of the University of Puerto Rico (UPR-MSC), San Juan, PR, USA; Puerto Rico Center for Environmental Neuroscience, Institute of Neurobiology, Medical Sciences Campus of the University of Puerto Rico, San Juan, PR, USA
[Ti] Título:Alterations of larval photo-dependent swimming responses (PDR): New endpoints for rapid and diagnostic screening of aquatic contamination.
[So] Source:Ecotoxicol Environ Saf;147:670-680, 2018 Jan.
[Is] ISSN:1090-2414
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Detection and toxicity assessment of waterborne contaminants are crucial for protecting human health and the environment. Development of easy-to-implement, rapid and cost-effective tools to measure anthropogenic effects on watersheds are critical for responsible management, particularly in times of increasing development and urbanization. Traditionally, environmental toxicology has focused on limited endpoints, such as lethality and fertility, which are directly affecting population levels. However, more sensitive readings are needed to assess sub-lethal effects. Monitoring of contaminant-induced behavior alterations was proposed before, but is difficult to implement in the wild and performing it in aquatic laboratory models seem more suited. For this purpose, we adapted a photo-dependent swimming response (PDR) that was previously described in zebrafish larva. We first asked if PDR was present in other aquatic animals. We measured PDR in larvae from two freshwater prawn species (Macrobrachium rosenbergii, MR, and Macrobrachium carcinus, MC) and from another fish the fathead minnow (FHM, Pimephales promelas). In all, we found a strong and reproducible species-specific PDR, which is arguing that this behavior is important, therefore an environmental relevant endpoint. Next, we measured PDR in fish larvae after acute exposure to copper, a common waterborne contaminant. FHM larvae were hyperactive at all tested concentrations in contrast to ZF larvae, which exhibited a concentration-dependent hyperactivity. In addition to this well-accepted anxiety-like behavior, we examined two more: photo-stimulated startle response (PSSR) and center avoidance (CA). Both were significantly increased. Therefore, PDR measures after acute exposure to this waterborne contaminant provided as sensitive readout for its detection and toxicity assessment. This approach represents an opportunity to diagnostically examine any substance, even when present in complex mixtures like ambient surface waters. Mechanistic studies of toxicity using the extensive molecular tool kit of ZF could be a direct extension of such approaches.
[Mh] Termos MeSH primário: Cobre/toxicidade
Monitoramento Ambiental/métodos
Larva/efeitos dos fármacos
Luz
Natação
Poluentes Químicos da Água/toxicidade
[Mh] Termos MeSH secundário: Animais
Comportamento Animal/efeitos dos fármacos
Comportamento Animal/efeitos da radiação
Peixes/fisiologia
Água Doce/química
Seres Humanos
Larva/fisiologia
Larva/efeitos da radiação
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Water Pollutants, Chemical); 789U1901C5 (Copper)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180309
[Lr] Data última revisão:
180309
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170922
[St] Status:MEDLINE


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[PMID]:28858706
[Au] Autor:Modlitbová P; Novotný K; Porízka P; Klus J; Lubal P; Zlámalová-Gargosová H; Kaiser J
[Ad] Endereço:Central European Institute of Technology (CEITEC) Brno University of Technology, Technická 3058/10, 616 00 Brno, Czech Republic. Electronic address: Pavlina.Skarkova@ceitec.vutbr.cz.
[Ti] Título:Comparative investigation of toxicity and bioaccumulation of Cd-based quantum dots and Cd salt in freshwater plant Lemna minor L.
[So] Source:Ecotoxicol Environ Saf;147:334-341, 2018 Jan.
[Is] ISSN:1090-2414
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:The purpose of this study was to determine the toxicity of two different sources of cadmium, i.e. CdCl and Cd-based Quantum Dots (QDs), for freshwater model plant Lemna minor L. Cadmium telluride QDs were capped with two coating ligands: glutathione (GSH) or 3-mercaptopropionic acid (MPA). Growth rate inhibition and final biomass inhibition of L. minor after 168-h exposure were monitored as toxicity endpoints. Dose-response curves for Cd toxicity and EC50 values were statistically evaluated for all sources of Cd to uncover possible differences among the toxicities of tested compounds. Total Cd content and its bioaccumulation factors (BAFs) in L. minor after the exposure period were also determined to distinguish Cd bioaccumulation patterns with respect to different test compounds. Laser-Induced Breakdown Spectroscopy (LIBS) with lateral resolution of 200µm was employed in order to obtain two-dimensional maps of Cd spatial distribution in L. minor fronds. Our results show that GSH- and MPA-capped Cd-based QDs have similar toxicity for L. minor, but are significantly less toxic than CdCl . However, both sources of Cd lead to similar patterns of Cd bioaccumulation and distribution in L. minor fronds. Our results are in line with previous reports that the main mediators of Cd toxicity and bioaccumulation in aquatic plants are Cd ions dissolved from Cd-based QDs.
[Mh] Termos MeSH primário: Araceae/efeitos dos fármacos
Cloreto de Cádmio/toxicidade
Compostos de Cádmio/toxicidade
Monitoramento Ambiental/métodos
Pontos Quânticos/toxicidade
Telúrio/toxicidade
Poluentes Químicos da Água/toxicidade
[Mh] Termos MeSH secundário: Ácido 3-Mercaptopropiônico/química
Adsorção
Araceae/crescimento & desenvolvimento
Araceae/metabolismo
Biomassa
Cloreto de Cádmio/metabolismo
Compostos de Cádmio/metabolismo
Água Doce/química
Glutationa/química
Modelos Teóricos
Pontos Quânticos/metabolismo
Telúrio/metabolismo
Poluentes Químicos da Água/química
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Cadmium Compounds); 0 (Water Pollutants, Chemical); B03TJ3QU9M (3-Mercaptopropionic Acid); GAN16C9B8O (Glutathione); J6K4F9V3BA (Cadmium Chloride); NQA0O090ZJ (Tellurium); STG188WO13 (cadmium telluride)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180309
[Lr] Data última revisão:
180309
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170901
[St] Status:MEDLINE


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[PMID]:29458494
[Au] Autor:Hwang WM; Kim SM; Kang K; Ahn TY
[Ad] Endereço:Department of Microbiology, College of Natural Sciences, Dankook University, Cheonan 31116, Republic of Korea.
[Ti] Título:Uliginosibacterium sediminicola sp. nov., isolated from freshwater sediment.
[So] Source:Int J Syst Evol Microbiol;68(3):924-929, 2018 Mar.
[Is] ISSN:1466-5034
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Strain M1-21 is a Gram-stain-negative, strictly aerobic and short-rod-shaped bacterium, motile by means of a single polar flagellum; it was isolated from freshwater sediment in Korea. It grew at 10-40 °C (optimum 25 °C), pH 6.0-8.0 (optimum pH 7.0) and with 0-0.75 % (w/v) NaCl (optimal growth occurred in the absence of NaCl) on R2A agar, and it accumulated poly-ß-hydroxybutyrate granules inside the cells. According to 16S rRNA gene sequence analysis, strain M1-21 showed highest sequence similarity with Uliginosibacterium gangwonense (94.7 %) and Uliginosibacterium paludis (94.4 %). Phylogenetic analysis of the 16S rRNA gene sequences revealed that strain M1-21 belongs to the genus Uliginosibacterium. The DNA G+C content of strain M1-21 was 61.9 mol%. The predominant respiratory quinone was ubiquinone-8. The major fatty acids (>10 % of the total) were C16 : 0 and summed feature 3 (C16 : 1ω6c and/or C16 : 1ω7c), and the major polar lipids were diphosphatidylglycerol, phosphatidylglycerol and phosphatidylethanolamine. Strain M1-21 showed distinct phenotypic characteristics that differentiated it from species of the genus Uliginosibacterium. Based on these results, strain M1-21 represents a novel species of the genus Uliginosibacterium, for which the name Uliginosibacterium sediminicola sp. nov. is proposed. The type strain is M1-21 (=KACC 19271 =JCM 32000 ).
[Mh] Termos MeSH primário: Água Doce/microbiologia
Sedimentos Geológicos/microbiologia
Filogenia
Rhodocyclaceae/classificação
[Mh] Termos MeSH secundário: Técnicas de Tipagem Bacteriana
Composição de Bases
DNA Bacteriano/genética
Ácidos Graxos/química
Hidroxibutiratos/química
Fosfolipídeos/química
Poliésteres/química
RNA Ribossômico 16S/genética
República da Coreia
Rhodocyclaceae/genética
Rhodocyclaceae/isolamento & purificação
Análise de Sequência de DNA
Ubiquinona/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Bacterial); 0 (Fatty Acids); 0 (Hydroxybutyrates); 0 (Phospholipids); 0 (Polyesters); 0 (RNA, Ribosomal, 16S); 1339-63-5 (Ubiquinone); 26063-00-3 (poly-beta-hydroxybutyrate); CQA993F7P8 (ubiquinone 8)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180221
[St] Status:MEDLINE
[do] DOI:10.1099/ijsem.0.002611


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[PMID]:28985654
[Au] Autor:Tolussi CE; Gomes ADO; Kumar A; Ribeiro CS; Nostro FLL; Bain PA; de Souza GB; Cuña RD; Honji RM; Moreira RG
[Ad] Endereço:Laboratório de Metabolismo e Reprodução de Organismos Aquáticos, Departamento de Fisiologia, Instituto de Biociências, Universidade de São Paulo. Rua do Matão, Trav.14, n° 321, 05508-090 São Paulo, SP, Brazil. Electronic address: ctolussi@usp.br.
[Ti] Título:Environmental pollution affects molecular and biochemical responses during gonadal maturation of Astyanax fasciatus (Teleostei: Characiformes: Characidae).
[So] Source:Ecotoxicol Environ Saf;147:926-934, 2018 Jan.
[Is] ISSN:1090-2414
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Endocrine disrupting compounds (EDCs) have the potential to alter fish reproduction at various levels of organization. The aim of this study was to assess the impact of a natural environment with heavily anthropogenic influence on the physiological processes involved in reproduction in the freshwater fish lambari (Astyanax fasciatus) using different biomarkers. Adult males and females were collected in different seasons from two distinct sites in the same watershed: Ponte Nova Reservoir (PN) considered a pristine or small anthropogenic influence reference point; and Billings Reservoir (Bil), subjected to a large anthropogenic impact. Biological indices, such as hepatosomatic index and gonadosomatic index (GSI), gonadal histomorphology, fecundity, and biomarkers such as plasma levels of estradiol (E2) as well as hepatic gene expression of its alfa nuclear receptor (ERα), were analyzed. Hepatic vitellogenin (VTG) gene expression was evaluated in both sexes, as an indicator of xenoestrogen exposure. Females collected at PN presented a typical annual variation reflected in GSI, whereas for those sampled at Bil the index did not change through the seasons. The higher concentration of E2 in males collected at Bil during spring/2013, together with the detection of VTG gene expression, suggest the presence of EDCs in the water. These EDCs may have also influenced fecundity of females from Bil, which was higher during winter and spring/2013. Gene expression of ERα and ovarian morphology did not differ between fish from both sites. Water conditions from Bil reservoir impacted by anthropic activity clearly interfered mainly with biomarkers of biological effect such as plasma E2 levels and absolute and relative fecundity, but also altered biomarkers of exposure as VTG gene expression. These facts support the notion that waterborne EDCs are capable of causing estrogenic activity in A. fasciatus.
[Mh] Termos MeSH primário: Characidae/metabolismo
Disruptores Endócrinos/toxicidade
Monitoramento Ambiental/métodos
Gônadas/efeitos dos fármacos
Organogênese/efeitos dos fármacos
Poluentes Químicos da Água/toxicidade
[Mh] Termos MeSH secundário: Animais
Biomarcadores/metabolismo
Brasil
Characidae/crescimento & desenvolvimento
Disruptores Endócrinos/análise
Estradiol/metabolismo
Feminino
Fertilidade/efeitos dos fármacos
Água Doce/química
Expressão Gênica/efeitos dos fármacos
Gônadas/crescimento & desenvolvimento
Gônadas/patologia
Masculino
Reprodução/efeitos dos fármacos
Estações do Ano
Vitelogeninas/metabolismo
Poluentes Químicos da Água/análise
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Biomarkers); 0 (Endocrine Disruptors); 0 (Vitellogenins); 0 (Water Pollutants, Chemical); 4TI98Z838E (Estradiol)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171008
[St] Status:MEDLINE


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[PMID]:28968938
[Au] Autor:Rotini A; Gallo A; Parlapiano I; Berducci MT; Boni R; Tosti E; Prato E; Maggi C; Cicero AM; Migliore L; Manfra L
[Ad] Endereço:Department of Biology, University Tor Vergata, Rome, Italy; Institute for Environmental Protection and Research (ISPRA), Rome, Italy.
[Ti] Título:Insights into the CuO nanoparticle ecotoxicity with suitable marine model species.
[So] Source:Ecotoxicol Environ Saf;147:852-860, 2018 Jan.
[Is] ISSN:1090-2414
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Metal oxide nanoparticles, among them copper oxide nanoparticles (CuO NPs), are widely used in different applications (e.g. batteries, gas sensors, superconductors, plastics and metallic coatings), increasing their potential release in the environment. In aquatic matrix, the behavior of CuO NPs may strongly change, depending on their surface charge and some physical-chemical characteristics of the medium (e.g. ionic strength, salinity, pH and natural organic matter content). Ecotoxicity of CuO NPs to aquatic organisms was mainly studied on freshwater species, few tests being performed on marine biota. The aim of this study was to assess the toxicity of CuO NPs on suitable indicator species, belonging to the ecologically relevant level of consumers. The selected bioassays use reference protocols to identify Effect/Lethal Concentrations (E(L)C), by assessing lethal and sub-lethal endpoints. Mortality tests were performed on rotifer (Brachionus plicatilis), shrimp (Artemia franciscana) and copepod (Tigriopus fulvus). While moult release failure and fertilization rate were studied, as sub-lethal endpoints, on T. fulvus and sea urchin (Paracentrotus lividus), respectively. The size distribution and sedimentation rates of CuO NPs, together with the copper dissolution, were also analyzed in the exposure media. The CuO NP ecotoxicity assessment showed a concentration-dependent response for all species, indicating similar mortality for B. plicatilis (48hLC = 16.94 ± 2.68mg/l) and T. fulvus (96hLC = 12.35 ± 0.48mg/l), followed by A. franciscana (48hLC = 64.55 ± 3.54mg/l). Comparable EC values were also obtained for the sub-lethal endpoints in P. lividus (EC = 2.28 ± 0.06mg/l) and T. fulvus (EC = 2.38 ± 0.20mg/l). Copper salts showed higher toxicity than CuO NPs for all species, with common sensitivity trend as follows: P. lividus ≥ T. fulvus (sublethal endpoint) ≥ B. plicatilis >T. fulvus (lethal endpoint) >A. franciscana. CuO NP micrometric aggregates and high sedimentation rates were observed in the exposure media, with different particle size distributions depending on the medium. The copper dissolution was about 0.16% of the initial concentration, comparable to literature values. The integrated ecotoxicological-physicochemical approach was used to better describe CuO NP toxicity and behavior. In particular, the successful application of ecotoxicological reference protocols allowed to produce reliable L(E)C data useful to identify thresholds and assess potential environmental hazard due to NPs.
[Mh] Termos MeSH primário: Organismos Aquáticos/efeitos dos fármacos
Cobre/toxicidade
Nanopartículas Metálicas/toxicidade
Poluentes Químicos da Água/toxicidade
[Mh] Termos MeSH secundário: Animais
Ecotoxicologia
Água Doce
Modelos Animais
Tamanho da Partícula
Salinidade
Especificidade da Espécie
Propriedades de Superfície
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Water Pollutants, Chemical); 789U1901C5 (Copper); V1XJQ704R4 (cupric oxide)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171004
[St] Status:MEDLINE


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[PMID]:27774651
[Au] Autor:Alharbi HA; Alcorn J; Al-Mousa A; Giesy JP; Wiseman SB
[Ad] Endereço:Toxicology Centre, University of Saskatchewan, Saskatoon, SK, Canada.
[Ti] Título:Toxicokinetics and toxicodynamics of chlorpyrifos is altered in embryos of Japanese medaka exposed to oil sands process-affected water: evidence for inhibition of P-glycoprotein.
[So] Source:J Appl Toxicol;37(5):591-601, 2017 05.
[Is] ISSN:1099-1263
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Oil sands process-affected water (OSPW) is generated during extraction of bitumen in the surface mining oil sands industry in Alberta, Canada. Studies were performed in vitro by use of Caco-2 cells, and in vivo with larvae of Japanese medaka (Oryzias latipes) to determine if organic compounds from the aqueous phase of OSPW inhibit ATP binding cassette protein ABCB1 (permeability-glycoprotein, P-gp). Neutral and basic fractions of OSPW inhibited activity of P-gp in Caco-2 cells by 1.9- and 2.0-fold, respectively, while the acidic fraction had the least effect. The organophosphate pesticides chlorpyrifos (a substrate of P-gp) and malathion (not a substrate of P-gp), were used as model chemicals to investigate inhibition of P-gp in larvae. Co-exposure to chlorpyrifos and an extract of OSPW containing basic and neutral compounds reduced survival of larvae to 26.5% compared to survival of larvae exposed only to chlorpyrifos, which was 93.7%. However, co-exposure to malathion and the extract of OSPW did not cause acute lethality compared to exposure only to malathion. Accumulation and bioconcentration of chlorpyrifos, but not malathion, was greater in larvae co-exposed with the extract of OSPW. The terminal elimination half-life of chlorpyrifos in larvae exposed to chlorpyrifos in freshwater was 5 days compared with 11.3 days in larvae exposed to chlorpyrifos in OSPW. Results suggest that in non-acute exposures, basic and neutral organic compounds in the water-soluble fraction of OSPW inhibit activity of P-gp, which suggests that OSPW has the potential to cause adverse effects by chemosensitization. Copyright © 2016 John Wiley & Sons, Ltd.
[Mh] Termos MeSH primário: Membro 1 da Subfamília B de Cassetes de Ligação de ATP/antagonistas & inibidores
Clorpirifos/toxicidade
Inseticidas/toxicidade
Campos de Petróleo e Gás
Oryzias/fisiologia
Poluentes Químicos da Água/toxicidade
[Mh] Termos MeSH secundário: Subfamília B de Transportador de Cassetes de Ligação de ATP/metabolismo
Alberta
Animais
Carga Corporal (Radioterapia)
Células CACO-2
Sobrevivência Celular/efeitos dos fármacos
Clorpirifos/farmacocinética
Embrião não Mamífero
Água Doce
Meia-Vida
Seres Humanos
Inseticidas/farmacocinética
Larva
Malation/toxicidade
Oryzias/metabolismo
Análise de Sobrevida
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (ABCB1 protein, human); 0 (ATP Binding Cassette Transporter, Sub-Family B); 0 (ATP-Binding Cassette, Sub-Family B, Member 1); 0 (Insecticides); 0 (Water Pollutants, Chemical); JCS58I644W (Chlorpyrifos); U5N7SU872W (Malathion)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180307
[Lr] Data última revisão:
180307
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161025
[St] Status:MEDLINE
[do] DOI:10.1002/jat.3397



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