Base de dados : MEDLINE
Pesquisa : H01 [Categoria DeCS]
Referências encontradas : 480 [refinar]
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[PMID]:29026204
[Au] Autor:Mitchell MJ; Jain RK; Langer R
[Ad] Endereço:Department of Bioengineering, University of Pennsylvania, 240 Skirkanich Hall, 210 S. 33rd Street, Philadelphia, Pennsylvania 19104, USA.
[Ti] Título:Engineering and physical sciences in oncology: challenges and opportunities.
[So] Source:Nat Rev Cancer;17(11):659-675, 2017 Nov.
[Is] ISSN:1474-1768
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The principles of engineering and physics have been applied to oncology for nearly 50 years. Engineers and physical scientists have made contributions to all aspects of cancer biology, from quantitative understanding of tumour growth and progression to improved detection and treatment of cancer. Many early efforts focused on experimental and computational modelling of drug distribution, cell cycle kinetics and tumour growth dynamics. In the past decade, we have witnessed exponential growth at the interface of engineering, physics and oncology that has been fuelled by advances in fields including materials science, microfabrication, nanomedicine, microfluidics, imaging, and catalysed by new programmes at the National Institutes of Health (NIH), including the National Institute of Biomedical Imaging and Bioengineering (NIBIB), Physical Sciences in Oncology, and the National Cancer Institute (NCI) Alliance for Nanotechnology. Here, we review the advances made at the interface of engineering and physical sciences and oncology in four important areas: the physical microenvironment of the tumour and technological advances in drug delivery; cellular and molecular imaging; and microfluidics and microfabrication. We discussthe research advances, opportunities and challenges for integrating engineering and physical sciences with oncology to develop new methods to study, detect and treat cancer, and we also describe the future outlook for these emerging areas.
[Mh] Termos MeSH primário: Engenharia Biomédica
Oncologia
Disciplinas das Ciências Naturais
Neoplasias/diagnóstico
Neoplasias/terapia
[Mh] Termos MeSH secundário: Animais
Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171115
[Lr] Data última revisão:
171115
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171014
[St] Status:MEDLINE
[do] DOI:10.1038/nrc.2017.83


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[PMID]:28682213
[Au] Autor:Hebebrand J
[Ad] Endereço:1 Klinik für Psychiatrie, Psychosomatik und Psychotherapie des Kindes- und Jugendalters, LVR Klinikum Essen, Universitätsklinik Essen, Universität Duisburg-Essen, Essen.
[Ti] Título:[The March for Science ­ challenges for education in natural sciences and research].
[Ti] Título:Der "March for Science" ­ Herausforderungen für den naturwissenschaftlichen Unterricht und die Forschung..
[So] Source:Z Kinder Jugendpsychiatr Psychother;45(4):261-263, 2017 07.
[Is] ISSN:1422-4917
[Cp] País de publicação:Switzerland
[La] Idioma:ger
[Mh] Termos MeSH primário: Comunicação
Dissidências e Disputas
Comportamento de Massa
Disciplinas das Ciências Naturais/educação
Disciplinas das Ciências Naturais/tendências
Opinião Pública
Pesquisa/educação
Pesquisa/tendências
[Mh] Termos MeSH secundário: Adolescente
Criança
Cultura
Currículo/tendências
Previsões
Alemanha
Seres Humanos
Cooperação Internacional
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170828
[Lr] Data última revisão:
170828
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170707
[St] Status:MEDLINE
[do] DOI:10.1024/1422-4917/a000531


  3 / 480 MEDLINE  
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[PMID]:28441842
[Au] Autor:Qin SH; Huang QS; Yao SZ
[Ad] Endereço:Department of Obstetrics and Gynecology, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.
[Ti] Título:[Analysis of funding of projects on obstetrics and gynecology supported by National Natural Science Foundation of China from 2007 to 2016].
[So] Source:Zhonghua Fu Chan Ke Za Zhi;52(4):254-260, 2017 Apr 25.
[Is] ISSN:0529-567X
[Cp] País de publicação:China
[La] Idioma:chi
[Ab] Resumo:To summarize the funding of scientific research projects on obstetrics and gynecology by National Natural Science Foundation of China (NSFC) from 2007 to 2016 and to display the hotspots of scientific research on obstetrics and gynecology. A systemic search was performed for the information of projects supported by NSFC from 2007 to 2016. The indicators for analysis included the number of projects, total investment, project categories, research units and research field. The research direction of each project was decided based on title, summary and key words provided by the profile of each project. The total investment on obstetrics and gynecology by NSFC was 23.214 million with a total of 82 projects in 2007. It increased year by year and reached the peak in 2014 (359 projects 208.990 million). The investment and number of projects remained stable after 2014. General projects (1 109 projects 608.000 million) formed the majority of projects. Youth science fund projects (1 035 projects 214.976 million) increased steadily and the number was nearly equal to general projects. There were only a small amount of key projects (20 projects 54.720 million) and major projects (7 projects 38.400 million). The investment varied in different research units. The greatest 10 units (less than 6% of total), including 7 comprehensive universities, 2 medical universities and 1 institute of medicine, got 1 113 projects invested (43.84% of total, 1 113/2 539). The hot areas like gynecological tumor (920 projects 350.615 million), hypertensive disorders complicating pregnancy (91 projects 37.470 million) and polycystic ovarian syndrome (77 projects 29.540 million) were more likely to receive investment, while some interdisciplinary science like maternal and child health (28 projects 12.050 million), imaging and biomedicine (37 projects 14.770 million) began to achieve attention in recent years. The number of researches invested will be increased for the scientific research in obstetrics and gynecology especially the areas of research focus, although the amount allocated for each will be decreased relatively. Besides, multidisciplinary work will be performed so as to develop obstetrics and gynecology of China to a high level.
[Mh] Termos MeSH primário: Apoio Financeiro
Fundações
Ginecologia
Obstetrícia
Apoio à Pesquisa como Assunto
[Mh] Termos MeSH secundário: Pesquisa Biomédica
China
Feminino
Fundações/economia
Seres Humanos
Disciplinas das Ciências Naturais
Neoplasias
Apoio à Pesquisa como Assunto/economia
Estados Unidos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170724
[Lr] Data última revisão:
170724
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170427
[St] Status:MEDLINE
[do] DOI:10.3760/cma.j.issn.0529-567X.2017.04.008


  4 / 480 MEDLINE  
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[PMID]:28370069
[Au] Autor:Arkema KK; Griffin R; Maldonado S; Silver J; Suckale J; Guerry AD
[Ad] Endereço:Natural Capital Project, School of Environmental and Forest Sciences, University of Washington, Seattle, Washington.
[Ti] Título:Linking social, ecological, and physical science to advance natural and nature-based protection for coastal communities.
[So] Source:Ann N Y Acad Sci;1399(1):5-26, 2017 Jul.
[Is] ISSN:1749-6632
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Interest in the role that ecosystems play in reducing the impacts of coastal hazards has grown dramatically. Yet the magnitude and nature of their effects are highly context dependent, making it difficult to know under what conditions coastal habitats, such as saltmarshes, reefs, and forests, are likely to be effective for saving lives and protecting property. We operationalize the concept of natural and nature-based solutions for coastal protection by adopting an ecosystem services framework that propagates the outcome of a management action through ecosystems to societal benefits. We review the literature on the basis of the steps in this framework, considering not only the supply of coastal protection provided by ecosystems but also the demand for protective services from beneficiaries. We recommend further attention to (1) biophysical processes beyond wave attenuation, (2) the combined effects of multiple habitat types (e.g., reefs, vegetation), (3) marginal values and expected damage functions, and, in particular, (4) community dependence on ecosystems for coastal protection and co-benefits. We apply our approach to two case studies to illustrate how estimates of multiple benefits and losses can inform restoration and development decisions. Finally, we discuss frontiers for linking social, ecological, and physical science to advance natural and nature-based solutions to coastal protection.
[Mh] Termos MeSH primário: Conservação dos Recursos Naturais/métodos
Ecossistema
Disciplinas das Ciências Naturais
Meio Social
[Mh] Termos MeSH secundário: Recifes de Corais
Tempestades Ciclônicas
Desastres/prevenção & controle
Inundações
Modelos Teóricos
Zonas Úmidas
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170815
[Lr] Data última revisão:
170815
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170404
[St] Status:MEDLINE
[do] DOI:10.1111/nyas.13322


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[PMID]:28219137
[Au] Autor:Zhang ZC; Dou D; Wang XY; Xie DH; Yan ZC
[Ad] Endereço:Department of Critical Care Medicine, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310009, China.
[Ti] Título:[Analysis of the application and funding projects of National Natural Science Foundation of China in the field of burns and plastic surgery from 2010 to 2016].
[So] Source:Zhonghua Shao Shang Za Zhi;33(2):65-67, 2017 Feb 20.
[Is] ISSN:1009-2587
[Cp] País de publicação:China
[La] Idioma:chi
[Ab] Resumo:We analyzed the data of application and funding projects of the National Natural Science Foundation of China (NSFC) during 2010-2016 in the field of burns and plastic surgery and summarized the NSFC funding pattern, the research hotspots, and weaknesses in this field. The NSFC has funded 460 projects in the field of burns and plastic surgery, with total funding of RMB 227.96 million. The scientific issues involved in the funding projects include orthotherapy against malformations, wound repair, basic research of burns, skin grafting, scars prevention, and regeneration of hair follicle and sweat glands. The research techniques involved in the funding projects are diversified. NSFC plays an important role in the scientific research and talents training in the field of burns and plastic surgery.
[Mh] Termos MeSH primário: Queimaduras
Apoio Financeiro
Cirurgia Plástica
[Mh] Termos MeSH secundário: Queimaduras/economia
China
Cicatriz
Fundações
Seres Humanos
Disciplinas das Ciências Naturais
Cirurgia Plástica/economia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170630
[Lr] Data última revisão:
170630
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170221
[St] Status:MEDLINE
[do] DOI:10.3760/cma.j.issn.1009-2587.2017.02.001


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[PMID]:28129352
[Au] Autor:Barthel R; Seidl R
[Ad] Endereço:Department of Earth Sciences, University of Gothenburg, Gothenburg, Sweden.
[Ti] Título:Interdisciplinary Collaboration between Natural and Social Sciences - Status and Trends Exemplified in Groundwater Research.
[So] Source:PLoS One;12(1):e0170754, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Interdisciplinary collaboration, particularly between natural and social sciences, is perceived as crucial to solving the significant challenges facing humanity. However, despite the need for such collaboration being expressed more frequently and intensely, it remains unclear to what degree such collaboration actually takes place, what trends and developments there are and which actors are involved. Previous studies, often based on bibliometric analysis of large bodies of literature, partly observed an increase in interdisciplinary collaboration in general, but in particular, the collaboration among distant fields was less explored. Other more qualitative studies found that interdisciplinary collaboration, particularly between natural and social scientists was not well developed, and obstacles abounded. To shed some light on the actual status and developments of this collaboration, we performed an analysis based on a sample of articles on groundwater research. We first identified journals and articles therein that potentially combined natural and social science aspects of groundwater research. Next, we analysed the disciplinary composition of their authors' teams, cited references, titles and keywords, making use of our detailed personal expertise in groundwater research and its interdisciplinary aspects. We combined several indicators developed from this analysis into a final classification of the degree of multidisciplinarity of each article. Covering the period between 1990 and 2014, we found that the overall percentage of multidisciplinary articles was in the low single-digit range, with only slight increases over the past decades. The interdisciplinarity of individuals plays a major role compared to interdisciplinarity involving two or more researchers. If collaboration with natural sciences takes place, social science is represented most often by economists. As a side result, we found that journals publishing multidisciplinary research had lower impact factors on average, and multidisciplinary papers were cited much less than mono-disciplinary ones.
[Mh] Termos MeSH primário: Água Subterrânea
Estudos Interdisciplinares
Disciplinas das Ciências Naturais/tendências
Ciências Sociais/tendências
[Mh] Termos MeSH secundário: Bibliometria
Comportamento Cooperativo
Seres Humanos
Editoração
Pesquisa
Pesquisadores/tendências
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170814
[Lr] Data última revisão:
170814
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170128
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0170754


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[PMID]:26754289
[Au] Autor:Galera A
[Ad] Endereço:Centro de Ciencias Humanas y Sociales, IH, CSIC Project HAR2013-43048-P, c/Albasanz 26-28, 28037, Madrid, Spain. andres.galera@cchs.csic.es.
[Ti] Título:The Impact of Lamarck's Theory of Evolution Before Darwin's Theory.
[So] Source:J Hist Biol;50(1):53-70, 2017 02.
[Is] ISSN:1573-0387
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:This paper analyzes the impact that Lamarckian evolutionary theory had in the scientific community during the period between the advent of Zoological Philosophy and the publication Origin of Species. During these 50 years Lamarck's model was a well known theory and it was discussed by the scientific community as a hypothesis to explain the changing nature of the fossil record throughout the history of Earth. Lamarck's transmutation theory established the foundation of an evolutionary model introducing a new way to research in nature. Darwin's selectionist theory was proposed in 1859 to explain the origin of species within this epistemological process. In this context, Charles Lyell's Principles of Geology and Auguste Comte's Cours de Philosophie Positive appear as two major works for the dissemination of Lamarck's evolutionary ideology after the death of the French naturalist in 1829.
[Mh] Termos MeSH primário: Evolução Biológica
Disciplinas das Ciências Naturais/história
[Mh] Termos MeSH secundário: História do Século XIX
Modelos Biológicos
Seleção Genética
[Pt] Tipo de publicação:HISTORICAL ARTICLE; JOURNAL ARTICLE
[Em] Mês de entrada:1706
[Cu] Atualização por classe:171020
[Lr] Data última revisão:
171020
[Sb] Subgrupo de revista:QIS
[Da] Data de entrada para processamento:160113
[St] Status:MEDLINE
[do] DOI:10.1007/s10739-015-9432-5


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[PMID]:28707870
[Au] Autor:Wood RJ
[Ti] Título:News of the Profession: Eloge.
[So] Source:Isis;107(3):597-600, 2016 09.
[Is] ISSN:0021-1753
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Genética/história
Ciência/história
[Mh] Termos MeSH secundário: República Tcheca
História do Século XX
História do Século XXI
Seres Humanos
Disciplinas das Ciências Naturais/história
[Pt] Tipo de publicação:BIOGRAPHY; HISTORICAL ARTICLE; JOURNAL ARTICLE; PORTRAITS
[Ps] Nome de pessoa como assunto:Orel V
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM; QIS
[Da] Data de entrada para processamento:170715
[St] Status:MEDLINE


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[PMID]:28707854
[Au] Autor:Bruno A
[Ti] Título:A Eurasian Mineralogy: Aleksandr Fersman's Conception of the Natural World.
[So] Source:Isis;107(3):518-39, 2016 09.
[Is] ISSN:0021-1753
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Thoroughly a product of imperial Russia's aristocratic culture, the mineralogist and geochemist Aleksandr Fersman rose to the top of the country's scientific establishment after the Bolsheviks took control. He then remained a staunch supporter of various industrial projects through much of the Stalinist period. This essay puts Fersman's thinking about the natural world in conversation with a quite distinctive mode of intellectual inquiry that developed contemporaneously. Eurasianism was a philosophical doctrine of a group of Russian émigrés who emphasized Russia's unique status straddling Europe and Asia. While Fersman did not belong to this group of thinkers, a number of his ideas drew on specific experiences in the environments of the Eurasian landmass. Indeed, the article argues that Fersman's dualistic understanding of nature, his advocacy for the field of geochemistry, his definition of deserts, and a scheme he proposed for industrial operations owed much to the Eurasian settings of the science he practiced. Furthermore, this case of a Eurasian mineralogist illuminates novel aspects of the interplay between national and global sciences.
[Mh] Termos MeSH primário: Minerais
Disciplinas das Ciências Naturais/história
Ciência/história
[Mh] Termos MeSH secundário: Comunismo/história
História do Século XX
Seres Humanos
Federação Russa
[Pt] Tipo de publicação:BIOGRAPHY; HISTORICAL ARTICLE; JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL; RESEARCH SUPPORT, NON-U.S. GOV'T; RESEARCH SUPPORT, U.S. GOV'T, NON-P.H.S.
[Ps] Nome de pessoa como assunto:Fersman A
[Nm] Nome de substância:
0 (Minerals)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM; QIS
[Da] Data de entrada para processamento:170715
[St] Status:MEDLINE


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[PMID]:28707853
[Au] Autor:Ratcliff J
[Ti] Título:The East India Company, the Company's Museum, and the Political Economy of Natural History in the Early Nineteenth Century.
[So] Source:Isis;107(3):495-517, 2016 09.
[Is] ISSN:0021-1753
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:At the turn of the nineteenth century, at its headquarters in the City of London, the Honourable East India Company established a new museum and library. By midcentury this museum would contain one of Europe's most extensive collections of the natural history, arts, and sciences of Asia. This essay uses the early history of the company's museum, focusing in particular on its natural history collections, to explore the material relationship between scientific practice and the imperial political economy. Much of the collections had been gathered in the wake of military campaigns, trade missions, or administrative surveys. Once specimens and reports arrived in Leadenhall Street and passed through the museum storage areas, this plunder would become the stuff of science, going on to feed the growth of disciplines, societies, and projects in Britain and beyond. In this way, the East India Company was integral to the information and communication infrastructures within which many sciences then operated. Collections-based disciplines and societies flourished in this period; their growth, it is argued, was coextensive with administrative and political economic change at institutions like the East India Company. The essay first explores the company's practices and patterns of collecting and then considers the consequences of this accumulation for aspects of scientific practice­particularly the growth of scientific societies­in both London and Calcutta.
[Mh] Termos MeSH primário: Medicina nas Artes
Museus/história
Disciplinas das Ciências Naturais/história
Ciência/história
[Mh] Termos MeSH secundário: Colonialismo/história
História do Século XIX
Seres Humanos
Índia
Londres
[Pt] Tipo de publicação:HISTORICAL ARTICLE; JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1708
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM; QIS
[Da] Data de entrada para processamento:170715
[St] Status:MEDLINE



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