Base de dados : MEDLINE
Pesquisa : H01.158.100.700 [Categoria DeCS]
Referências encontradas : 1407 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 141 ir para página                         

  1 / 1407 MEDLINE  
              next record last record
seleciona
para imprimir
Fotocópia
[PMID]:29283527
[Ti] Título:Vesalius' legacy. The Tabulae pictae of Girolamo Fabrici d' Acquapendente.
[So] Source:Vesalius;22(1):63-78, 2016 Jun.
[Is] ISSN:1373-4857
[Cp] País de publicação:Belgium
[La] Idioma:eng
[Ab] Resumo:Girolamo Fabrici d'Acquapendente (ca.1533­1619) left a rich collection of anatomical paintings in colours, which are today preserved in the Marciana Library in Venice. The third series, entitled De Anatomia Capitis Cerebri Nervorum, contains the only known illustrations by Fabrici regarding neuroanatomy since, apart from them, he never published on the nervous system. For this reason, a thorough study of these plates is pivotal to a better understanding of his contribution to the knowledge of the Nervous System. A recently found unpublished manuscript reporting on a lesson of Fabrici, given in the Anatomical Theather in Padua, constitutes to this day the only written description, however indirect, of this subject by him.
[Mh] Termos MeSH primário: Ilustração Médica/história
Neuroanatomia/história
Livros de Texto como Assunto/história
[Mh] Termos MeSH secundário: Anatomia Artística/história
História do Século XVI
História do Século XVII
Itália
[Pt] Tipo de publicação:BIOGRAPHY; HISTORICAL ARTICLE; JOURNAL ARTICLE; PORTRAITS
[Ps] Nome de pessoa como assunto:Fabrici d��� Acquapendente G
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180212
[Lr] Data última revisão:
180212
[Sb] Subgrupo de revista:QIS
[Da] Data de entrada para processamento:171229
[St] Status:MEDLINE


  2 / 1407 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28456809
[Au] Autor:Pearce JMS
[Ad] Endereço:Emeritus Consultant Neurologist, Department of Neurology, Hull Royal Infirmary, Hull, UK.
[Ti] Título:Samuel Thomas Soemmerring (1755-1830): The Naming of Cranial Nerves.
[So] Source:Eur Neurol;77(5-6):303-306, 2017.
[Is] ISSN:1421-9913
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:Samuel Thomas Soemmerring was a Prussian polymathic doctor with remarkable achievements in anatomy, draftsmanship and inventions. His naming of 12 pairs of cranial nerves in his graduation thesis is of particular importance. He also gave original descriptions of the macula, sensory pathways and of the substantia nigra. His non-medical contributions were diverse and included criticism of the guillotine, invention of a telegraphic system, and discoveries in palaeontology.
[Mh] Termos MeSH primário: Nervos Cranianos
Neuroanatomia/história
[Mh] Termos MeSH secundário: História do Século XVIII
História do Século XIX
Seres Humanos
Masculino
[Pt] Tipo de publicação:BIOGRAPHY; HISTORICAL ARTICLE; JOURNAL ARTICLE; PORTRAITS
[Ps] Nome de pessoa como assunto:Soemmerring ST
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180108
[Lr] Data última revisão:
180108
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170501
[St] Status:MEDLINE
[do] DOI:10.1159/000475812


  3 / 1407 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28809960
[Au] Autor:Li Y; Wang D; Ascoli GA; Mitra P; Wang Y
[Ad] Endereço:Computer Science and Engineering Department, The Ohio State University, Columbus, OH 43221, United States of America.
[Ti] Título:Metrics for comparing neuronal tree shapes based on persistent homology.
[So] Source:PLoS One;12(8):e0182184, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:As more and more neuroanatomical data are made available through efforts such as NeuroMorpho.Org and FlyCircuit.org, the need to develop computational tools to facilitate automatic knowledge discovery from such large datasets becomes more urgent. One fundamental question is how best to compare neuron structures, for instance to organize and classify large collection of neurons. We aim to develop a flexible yet powerful framework to support comparison and classification of large collection of neuron structures efficiently. Specifically we propose to use a topological persistence-based feature vectorization framework. Existing methods to vectorize a neuron (i.e, convert a neuron to a feature vector so as to support efficient comparison and/or searching) typically rely on statistics or summaries of morphometric information, such as the average or maximum local torque angle or partition asymmetry. These simple summaries have limited power in encoding global tree structures. Based on the concept of topological persistence recently developed in the field of computational topology, we vectorize each neuron structure into a simple yet informative summary. In particular, each type of information of interest can be represented as a descriptor function defined on the neuron tree, which is then mapped to a simple persistence-signature. Our framework can encode both local and global tree structure, as well as other information of interest (electrophysiological or dynamical measures), by considering multiple descriptor functions on the neuron. The resulting persistence-based signature is potentially more informative than simple statistical summaries (such as average/mean/max) of morphometric quantities-Indeed, we show that using a certain descriptor function will give a persistence-based signature containing strictly more information than the classical Sholl analysis. At the same time, our framework retains the efficiency associated with treating neurons as points in a simple Euclidean feature space, which would be important for constructing efficient searching or indexing structures over them. We present preliminary experimental results to demonstrate the effectiveness of our persistence-based neuronal feature vectorization framework.
[Mh] Termos MeSH primário: Algoritmos
Neuroanatomia/métodos
Neurônios/citologia
[Mh] Termos MeSH secundário: Animais
Eletrofisiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171011
[Lr] Data última revisão:
171011
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170816
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0182184


  4 / 1407 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28787487
[Au] Autor:Georgopoulos AP; Georgopoulos A
[Ad] Endereço:Brain Sciences Center, Department of Veterans Affairs Medical Center, Minneapolis, Minnesota.
[Ti] Título:The Beautiful Brain and the Influence of Santiago Ramón y Cajal on Medicine.
[So] Source:JAMA;318(6):502-504, 2017 Aug 08.
[Is] ISSN:1538-3598
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Anatomia Artística/história
Encéfalo/citologia
Neuroanatomia/história
Neurônios/citologia
[Mh] Termos MeSH secundário: História do Século XIX
História do Século XX
Neurologia/história
Neurônios/fisiologia
Prêmio Nobel
[Pt] Tipo de publicação:BIOGRAPHY; HISTORICAL ARTICLE; JOURNAL ARTICLE; PORTRAITS
[Ps] Nome de pessoa como assunto:Ramón y Cajal S
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170920
[Lr] Data última revisão:
170920
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170809
[St] Status:MEDLINE
[do] DOI:10.1001/jama.2017.9858


  5 / 1407 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28683264
[Au] Autor:DeFelipe J
[Ad] Endereço:Instituto Cajal (CSIC) and Laboratorio Cajal de Circuitos Corticales (CTB/UPM), Madrid, Spain. Electronic address: defelipe@cajal.csic.es.
[Ti] Título:Neuroanatomy and Global Neuroscience.
[So] Source:Neuron;95(1):14-18, 2017 Jul 05.
[Is] ISSN:1097-4199
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Our brains are like a dense forest-a complex, seemingly impenetrable terrain of interacting cells mediating cognition and behavior. However, we should view the challenge of understanding the brain with optimism, provided that we choose appropriate strategies for the development of global neuroscience.
[Mh] Termos MeSH primário: Encéfalo/anatomia & histologia
Encéfalo/fisiologia
Neuroanatomia
Neurociências
[Mh] Termos MeSH secundário: Mapeamento Encefálico
Cognição
Comportamento Cooperativo
Seres Humanos
Comunicação Interdisciplinar
Microscopia Eletrônica
Rede Nervosa/anatomia & histologia
Rede Nervosa/fisiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170801
[Lr] Data última revisão:
170801
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170707
[St] Status:MEDLINE


  6 / 1407 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28377435
[Au] Autor:Slominski TN; Momsen JL; Montplaisir LM
[Ad] Endereço:Department of Biological Science, North Dakota State University, Fargo, North Dakota tara.slominski@ndsu.edu.
[Ti] Título:Drawing on student knowledge of neuroanatomy and neurophysiology.
[So] Source:Adv Physiol Educ;41(2):212-221, 2017 Jun 01.
[Is] ISSN:1522-1229
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Drawings are an underutilized assessment format in Human Anatomy and Physiology (HA&P), despite their potential to reveal student content understanding and alternative conceptions. This study used student-generated drawings to explore student knowledge in a HA&P course. The drawing tasks in this study focused on chemical synapses between neurons, an abstract concept in HA&P. Using two preinstruction drawing tasks, students were asked to depict synaptic transmission and summation. In response to the first drawing task, 20% of students ( = 352) created accurate representations of neuron anatomy. The remaining students created drawings suggesting an inaccurate or incomplete understanding of synaptic transmission. Of the 208 inaccurate student-generated drawings, 21% depicted the neurons as touching. When asked to illustrate summation, only 10 students (roughly 4%) were able to produce an accurate drawing. Overall, students were more successful at drawing anatomy (synapse) than physiology (summation) before formal instruction. The common errors observed in student-generated drawings indicate students do not enter the classroom as blank slates. The error of "touching" neurons in a chemical synapse suggests that students may be using intuitive or experiential knowledge when reasoning about physiological concepts. These results ) support the utility of drawing tasks as a tool to reveal student content knowledge about neuroanatomy and neurophysiology; and ) suggest students enter the classroom with better knowledge of anatomy than physiology. Collectively, the findings from this study inform both practitioners and researchers about the prevalence and nature of student difficulties in HA&P, while also demonstrating the utility of drawing in revealing student knowledge.
[Mh] Termos MeSH primário: Avaliação Educacional/métodos
Conhecimento
Neuroanatomia/educação
Neurofisiologia/educação
Estudantes/estatística & dados numéricos
[Mh] Termos MeSH secundário: Compreensão
Avaliação Educacional/normas
Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171103
[Lr] Data última revisão:
171103
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170406
[St] Status:MEDLINE
[do] DOI:10.1152/advan.00129.2016


  7 / 1407 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28303019
[Au] Autor:Kim CK; Adhikari A; Deisseroth K
[Ad] Endereço:Neurosciences Program, Stanford University, 318 Campus Drive, Stanford, California 94305, USA.
[Ti] Título:Integration of optogenetics with complementary methodologies in systems neuroscience.
[So] Source:Nat Rev Neurosci;18(4):222-235, 2017 03 17.
[Is] ISSN:1471-0048
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Modern optogenetics can be tuned to evoke activity that corresponds to naturally occurring local or global activity in timing, magnitude or individual-cell patterning. This outcome has been facilitated not only by the development of core features of optogenetics over the past 10 years (microbial-opsin variants, opsin-targeting strategies and light-targeting devices) but also by the recent integration of optogenetics with complementary technologies, spanning electrophysiology, activity imaging and anatomical methods for structural and molecular analysis. This integrated approach now supports optogenetic identification of the native, necessary and sufficient causal underpinnings of physiology and behaviour on acute or chronic timescales and across cellular, circuit-level or brain-wide spatial scales.
[Mh] Termos MeSH primário: Neurociências/métodos
Optogenética/métodos
[Mh] Termos MeSH secundário: Animais
Eletrofisiologia/métodos
Neuroanatomia/métodos
Neuroimagem/métodos
Neurociências/tendências
Optogenética/tendências
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170614
[Lr] Data última revisão:
170614
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170318
[St] Status:MEDLINE
[do] DOI:10.1038/nrn.2017.15


  8 / 1407 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28230838
[Au] Autor:Lerch JP; van der Kouwe AJ; Raznahan A; Paus T; Johansen-Berg H; Miller KL; Smith SM; Fischl B; Sotiropoulos SN
[Ad] Endereço:Program in Neuroscience and Mental Health, The Hospital for Sick Children, Toronto, Canada.
[Ti] Título:Studying neuroanatomy using MRI.
[So] Source:Nat Neurosci;20(3):314-326, 2017 Feb 23.
[Is] ISSN:1546-1726
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The study of neuroanatomy using imaging enables key insights into how our brains function, are shaped by genes and environment, and change with development, aging and disease. Developments in MRI acquisition, image processing and data modeling have been key to these advances. However, MRI provides an indirect measurement of the biological signals we aim to investigate. Thus, artifacts and key questions of correct interpretation can confound the readouts provided by anatomical MRI. In this review we provide an overview of the methods for measuring macro- and mesoscopic structure and for inferring microstructural properties; we also describe key artifacts and confounds that can lead to incorrect conclusions. Ultimately, we believe that, although methods need to improve and caution is required in interpretation, structural MRI continues to have great promise in furthering our understanding of how the brain works.
[Mh] Termos MeSH primário: Encéfalo/anatomia & histologia
Processamento de Imagem Assistida por Computador
Imagem por Ressonância Magnética
Neuroanatomia
[Mh] Termos MeSH secundário: Envelhecimento/fisiologia
Artefatos
Seres Humanos
Processamento de Imagem Assistida por Computador/métodos
Imagem por Ressonância Magnética/métodos
Neuroanatomia/métodos
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170803
[Lr] Data última revisão:
170803
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170224
[St] Status:MEDLINE
[do] DOI:10.1038/nn.4501


  9 / 1407 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28192461
[Au] Autor:Raffan H; Guevar J; Poyade M; Rea PM
[Ad] Endereço:Laboratory of Human Anatomy, Thomson Building, School of Life Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, United Kingdom.
[Ti] Título:Canine neuroanatomy: Development of a 3D reconstruction and interactive application for undergraduate veterinary education.
[So] Source:PLoS One;12(2):e0168911, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Current methods used to communicate and present the complex arrangement of vasculature related to the brain and spinal cord is limited in undergraduate veterinary neuroanatomy training. Traditionally it is taught with 2-dimensional (2D) diagrams, photographs and medical imaging scans which show a fixed viewpoint. 2D representations of 3-dimensional (3D) objects however lead to loss of spatial information, which can present problems when translating this to the patient. Computer-assisted learning packages with interactive 3D anatomical models have become established in medical training, yet equivalent resources are scarce in veterinary education. For this reason, we set out to develop a workflow methodology creating an interactive model depicting the vasculature of the canine brain that could be used in undergraduate education. Using MR images of a dog and several commonly available software programs, we set out to show how combining image editing, segmentation and surface generation, 3D modeling and texturing can result in the creation of a fully interactive application for veterinary training. In addition to clearly identifying a workflow methodology for the creation of this dataset, we have also demonstrated how an interactive tutorial and self-assessment tool can be incorporated into this. In conclusion, we present a workflow which has been successful in developing a 3D reconstruction of the canine brain and associated vasculature through segmentation, surface generation and post-processing of readily available medical imaging data. The reconstructed model was implemented into an interactive application for veterinary education that has been designed to target the problems associated with learning neuroanatomy, primarily the inability to visualise complex spatial arrangements from 2D resources. The lack of similar resources in this field suggests this workflow is original within a veterinary context. There is great potential to explore this method, and introduce a new dimension into veterinary education and training.
[Mh] Termos MeSH primário: Educação em Veterinária/métodos
Imagem Tridimensional/métodos
Modelos Anatômicos
Neuroanatomia/métodos
[Mh] Termos MeSH secundário: Animais
Encéfalo/anatomia & histologia
Encéfalo/diagnóstico por imagem
Cães
Imagem por Ressonância Magnética/métodos
Reprodutibilidade dos Testes
Software
Tomografia Computadorizada por Raios X/métodos
Universidades
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170824
[Lr] Data última revisão:
170824
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170214
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0168911


  10 / 1407 MEDLINE  
              first record previous record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28139055
[Au] Autor:Thompson CA; Karelis J; Middleton FA; Gentile K; Coman IL; Radoeva PD; Mehta R; Fremont WP; Antshel KM; Faraone SV; Kates WR
[Ad] Endereço:Department of Psychiatry and Behavioral Sciences, SUNY Upstate Medical University, Syracuse, New York.
[Ti] Título:Associations between neurodevelopmental genes, neuroanatomy, and ultra high risk symptoms of psychosis in 22q11.2 deletion syndrome.
[So] Source:Am J Med Genet B Neuropsychiatr Genet;174(3):295-314, 2017 Apr.
[Is] ISSN:1552-485X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:22q11.2 deletion syndrome is a neurogenetic disorder resulting in the deletion of over 40 genes. Up to 40% of individuals with 22q11.2DS develop schizophrenia, though little is known about the underlying mechanisms. We hypothesized that allelic variation in functional polymorphisms in seven genes unique to the deleted region would affect lobar brain volumes, which would predict risk for psychosis in youth with 22q11.2DS. Participants included 56 individuals (30 males) with 22q11.2DS. Anatomic MR images were collected and processed using Freesurfer. Participants were genotyped for 10 SNPs in the COMT, DGCR8, GNB1L, PIK4CA, PRODH, RTN4R, and ZDHHC8 genes. All subjects were assessed for ultra high risk symptoms of psychosis. Allelic variation of the rs701428 SNP of RTN4R was significantly associated with volumetric differences in gray matter of the lingual gyrus and cuneus of the occipital lobe. Moreover, occipital gray matter volumes were robustly associated with ultra high risk symptoms of psychosis in the presence of the G allele of rs701428. Our results suggest that RTN4R, a relatively under-studied gene at the 22q11 locus, constitutes a susceptibility gene for psychosis in individuals with this syndrome through its alteration of the architecture of the brain. © 2017 Wiley Periodicals, Inc.
[Mh] Termos MeSH primário: Anormalidades Múltiplas/genética
Anormalidades Múltiplas/psicologia
Síndrome de DiGeorge/genética
Síndrome de DiGeorge/psicologia
Receptor Nogo 1/genética
Transtornos Psicóticos/genética
[Mh] Termos MeSH secundário: Adolescente
Alelos
Catecol O-Metiltransferase/genética
Deleção Cromossômica
Cromossomos Humanos Par 22/genética
Feminino
Estudos de Associação Genética
Predisposição Genética para Doença
Genótipo
Substância Cinzenta
Seres Humanos
Imagem por Ressonância Magnética
Masculino
Neuroanatomia
Transtornos do Neurodesenvolvimento/genética
Receptor Nogo 1/fisiologia
Lobo Occipital
Polimorfismo de Nucleotídeo Único/genética
Escalas de Graduação Psiquiátrica
Transtornos Psicóticos/etiologia
Transtornos Psicóticos/psicologia
Fatores de Risco
Esquizofrenia/genética
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Nogo Receptor 1); 0 (RTN4R protein, human); EC 2.1.1.6 (Catechol O-Methyltransferase)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170921
[Lr] Data última revisão:
170921
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170201
[St] Status:MEDLINE
[do] DOI:10.1002/ajmg.b.32515



página 1 de 141 ir para página                         
   


Refinar a pesquisa
  Base de dados : MEDLINE Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde