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[PMID]:29194308
[Au] Autor:Morales KA
[Ad] Endereço:About the Author Kathleen A. Morales, MSN, RN, CNE, is an assistant professor of nursing, Berry College Nursing Program, Mount Berry, Georgia. The author thanks Dr. Laura Kimble, professor at Georgia Baptist College of Nursing of Mercer University, for her support in developing this article. For more information, write to the author at kmorales@berry.edu.
[Ti] Título:Active Learning Strategies to Enhance Nursing Students' Knowledge of Pharmacology.
[So] Source:Nurs Educ Perspect;38(2):100-102, 2017 Mar/Apr.
[Is] ISSN:1536-5026
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:This article presents the author's experience using gaming and social media to enhance undergraduate nursing students' pharmacology knowledge. Although gaming may help with rote learning, active participation in gaming was not associated with higher exam or final course grades. Active participation in social media, on the other hand, was associated with higher exam and final course grades.
[Mh] Termos MeSH primário: Educação Técnica em Enfermagem/métodos
Farmacologia/educação
Aprendizagem Baseada em Problemas
Mídias Sociais
Jogos de Vídeo
[Mh] Termos MeSH secundário: Currículo
Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180227
[Lr] Data última revisão:
180227
[Sb] Subgrupo de revista:N
[Da] Data de entrada para processamento:171202
[St] Status:MEDLINE
[do] DOI:10.1097/01.NEP.0000000000000085


  2 / 7360 MEDLINE  
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[PMID]:29194243
[Au] Autor:Tinnon E; Newton R
[Ad] Endereço:About the Authors Elizabeth Tinnon, PhD, RN, CNE, is assistant professor, College of Nursing, University of Southern Mississippi, Hattiesburg. Rebecca Newton, DNP, RN, is assistant professor, College of Nursing, University of Southern Mississippi, Hattiesburg. For more information, contact Dr. Tinnon at elizabeth.tinnon@usm.edu.
[Ti] Título:Simulation in an Undergraduate Nursing Pharmacology Course: A Pilot Study.
[So] Source:Nurs Educ Perspect;38(1):37-39, 2017 Jan/Feb.
[Is] ISSN:1536-5026
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:This study examined the effectiveness of simulation as a method of teaching pharmacological concepts to nursing students; perceptions of satisfaction with simulation as a teaching strategy were also evaluated. Second-semester juniors participated in three simulations and completed the National League for Nursing Student Satisfaction and Self-Confidence in Learning Questionnaire and the Student Evaluation of Educational Quality Survey; a control group received traditional lectures. A unit exam on anticoagulant therapy content was administered to measure effectiveness. Findings support that simulation is as effective as traditional lecture for an undergraduate pharmacology course.
[Mh] Termos MeSH primário: Bacharelado em Enfermagem
Farmacologia/educação
Treinamento por Simulação/métodos
[Mh] Termos MeSH secundário: Currículo
Avaliação Educacional
Seres Humanos
Projetos Piloto
Inquéritos e Questionários
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180227
[Lr] Data última revisão:
180227
[Sb] Subgrupo de revista:N
[Da] Data de entrada para processamento:171202
[St] Status:MEDLINE
[do] DOI:10.1097/01.NEP.0000000000000098


  3 / 7360 MEDLINE  
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[PMID]:29194136
[Au] Autor:Geist MJ; Larimore D; Rawiszer H; Sager AWA
[Ti] Título:Flipped Versus Traditional Instruction and Achievement in a Baccalaureate Nursing Pharmacology Course.
[So] Source:Nurs Educ Perspect;36(2):114-115, 2015 Mar/Apr.
[Is] ISSN:1536-5026
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:: The researchers used a quantitative pretest-posttest nonequivalent control group quasi-experimental design to determine if there is a significant difference in content knowledge acquisition between traditional and flipped classroom methods. Analysis revealed that the flipped classroom approach was significantly different for three unit exams. The results did not show a significant difference in the means for the final exam. Knowledge gains on tests and students' positive responses support the use of the flipped classroom method.
[Mh] Termos MeSH primário: Currículo
Bacharelado em Enfermagem/métodos
Avaliação Educacional/métodos
Farmacologia/educação
[Mh] Termos MeSH secundário: Adulto
Feminino
Seres Humanos
Masculino
Modelos Educacionais
Aprendizagem Baseada em Problemas
Tennessee
Adulto Jovem
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180220
[Lr] Data última revisão:
180220
[Sb] Subgrupo de revista:N
[Da] Data de entrada para processamento:171202
[St] Status:MEDLINE
[do] DOI:10.5480/13-1292


  4 / 7360 MEDLINE  
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[PMID]:29233275
[Au] Autor:Oelschlaeger P
[Ad] Endereço:Department of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, 309 E. Second St., Pomona, CA 91766, United States. Electronic address: poelschlaeger@westernu.edu.
[Ti] Título:Change in self-assessed comfort level of first-year pharmacy students as an alternative approach to measure teaching effectiveness and learning outcomes.
[So] Source:Curr Pharm Teach Learn;9(3):383-390, 2017 May.
[Is] ISSN:1877-1300
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: Objective measures for assessing teaching effectiveness and learning outcomes in the pharmacy curriculum are needed for improving quality of instruction and faculty development. The purpose of this article is to introduce a new teaching assessment method that focuses on self-assessed change in student comfort with the topics taught rather than evaluation of the instructor and to evaluate its performance in comparison to conventional student evaluations of teaching (SET). METHODS: Six successive cohorts of first-year pharmacy students were surveyed regarding their comfort level at the beginning and end of a 10-week pharmacology course. The change in self-assessed comfort level (ΔSACL) was interpreted as the amount of learning that occurred. This indicator was compared to ratings of a statement from SET designed to obtain the same information. RESULTS: An increasing ΔSACL suggests an increase in learning over time. Differences were observed between ΔSACL and corresponding results from SET, suggesting that there could be extrinsic factors influencing the results. DISCUSSION AND CONCLUSIONS: The use of ΔSACL could provide an alternative or complementary approach to assess teaching effectiveness that focuses less on the instructor and more on the actual student learning outcomes.
[Mh] Termos MeSH primário: Educação em Farmácia
Avaliação Educacional/métodos
Autoeficácia
Estudantes de Farmácia
Ensino/normas
[Mh] Termos MeSH secundário: Feminino
Conhecimentos, Atitudes e Prática em Saúde
Seres Humanos
Aprendizagem
Masculino
Farmacologia/educação
Autoavaliação
Inquéritos e Questionários
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180214
[Lr] Data última revisão:
180214
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171214
[St] Status:MEDLINE


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[PMID]:27776546
[Au] Autor:Fisher D; Wicks P; Babar ZU
[Ad] Endereço:Infectious Disease Division, Department of Medicine, National University Hospital; National University Health Systems, 1E Kent Ridge Rd, Singapore, 119228, Singapore. mdcfda@nus.edu.sg.
[Ti] Título:Medicine and the future of health: reflecting on the past to forge ahead.
[So] Source:BMC Med;14(1):169, 2016 10 25.
[Is] ISSN:1741-7015
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The development of new therapies has a rich history, evolves quickly with societal trends, and will have an exciting future. The last century has seen an exponential increase in complex interactions between medical practitioners, pharmaceutical companies, governments and patients. We believe technology and societal expectations will open up the opportunity for more individuals to participate as information becomes more freely available and inequality less acceptable. Corporations must recognize that usual market forces do not function ideally in a setting where health is regarded as a human right, and as modern consumers, patients will increasingly take control of their own data, wellbeing, and even the means of production for developing their own treatments. Ethics and legislation will increasingly impact the processes that facilitate drug development, distribution and administration. This article collection is a cross-journal collaboration, between the Journal of Pharmaceutical Policy and Practice (JoPPP) and BMC Medicine that seeks to cover recent advances in drug development, medicines use, policy and access with high clinical and public health relevance in the future.The Medicine and the Future of Health article collection is a joint collection between BMC Medicine and Journal of Pharmaceutical Policy and Practice. Therefore, this Editorial by the guest editors has been published in both journals.
[Mh] Termos MeSH primário: Tratamento Farmacológico/tendências
Farmacologia/tendências
[Mh] Termos MeSH secundário: Indústria Farmacêutica/tendências
Saúde Global
Política de Saúde/tendências
Acesso aos Serviços de Saúde
Seres Humanos
Publicações/tendências
[Pt] Tipo de publicação:EDITORIAL; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1707
[Cu] Atualização por classe:180127
[Lr] Data última revisão:
180127
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161026
[St] Status:MEDLINE


  6 / 7360 MEDLINE  
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[PMID]:28467408
[Au] Autor:Jackson RC; Di Veroli GY; Koh SB; Goldlust I; Richards FM; Jodrell DI
[Ad] Endereço:Pharmacometrics Ltd, Cambridge, United Kingdom.
[Ti] Título:Modelling of the cancer cell cycle as a tool for rational drug development: A systems pharmacology approach to cyclotherapy.
[So] Source:PLoS Comput Biol;13(5):e1005529, 2017 May.
[Is] ISSN:1553-7358
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The dynamic of cancer is intimately linked to a dysregulation of the cell cycle and signalling pathways. It has been argued that selectivity of treatments could exploit loss of checkpoint function in cancer cells, a concept termed "cyclotherapy". Quantitative approaches that describe these dysregulations can provide guidance in the design of novel or existing cancer therapies. We describe and illustrate this strategy via a mathematical model of the cell cycle that includes descriptions of the G1-S checkpoint and the spindle assembly checkpoint (SAC), the EGF signalling pathway and apoptosis. We incorporated sites of action of four drugs (palbociclib, gemcitabine, paclitaxel and actinomycin D) to illustrate potential applications of this approach. We show how drug effects on multiple cell populations can be simulated, facilitating simultaneous prediction of effects on normal and transformed cells. The consequences of aberrant signalling pathways or of altered expression of pro- or anti-apoptotic proteins can thus be compared. We suggest that this approach, particularly if used in conjunction with pharmacokinetic modelling, could be used to predict effects of specific oncogene expression patterns on drug response. The strategy could be used to search for synthetic lethality and optimise combination protocol designs.
[Mh] Termos MeSH primário: Antineoplásicos/farmacologia
Antineoplásicos/uso terapêutico
Pontos de Checagem do Ciclo Celular/efeitos dos fármacos
Descoberta de Drogas/métodos
Modelos Biológicos
Neoplasias/tratamento farmacológico
[Mh] Termos MeSH secundário: Linhagem Celular Tumoral
Biologia Computacional
Seres Humanos
Farmacologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antineoplastic Agents)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:180124
[Lr] Data última revisão:
180124
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170504
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pcbi.1005529


  7 / 7360 MEDLINE  
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[PMID]:29209702
[Au] Autor:Hampton T
[Ti] Título:Body-on-a-Chip Reveals Multitissue Interactions During Drug Exposure.
[So] Source:JAMA;318(21):2069-2070, 2017 Dec 05.
[Is] ISSN:1538-3598
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Modelos Biológicos
Organoides/efeitos dos fármacos
Farmacologia
Engenharia Tecidual/métodos
[Mh] Termos MeSH secundário: Seres Humanos
Miniaturização
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171219
[Lr] Data última revisão:
171219
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171207
[St] Status:MEDLINE
[do] DOI:10.1001/jama.2017.17869


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[PMID]:28876905
[Au] Autor:Leippe P; Koehler Leman J; Trauner D
[Ad] Endereço:Department of Chemistry and Center for Integrated Protein Science Munich, Ludwig-Maximilians-Universität München , Butenandtstrasse 5-13, 81377 Munich, Germany.
[Ti] Título:Specificity and Speed: Tethered Photopharmacology.
[So] Source:Biochemistry;56(39):5214-5220, 2017 Oct 03.
[Is] ISSN:1520-4995
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Genetics and pharmacology are often seen as two distinct approaches to interrogating, elucidating, and manipulating biological systems. The former is renowned for its precision whereas the latter for its fast kinetics, reversibility, and practicality. Here, we show that both can be joined as "tethered pharmacology", wherein a genetically programmed bioconjugation site provides selectivity and a tethered pharmacophore provides function. The speed of onset, and especially cessation, of pharmacological activity can be greatly enhanced by incorporating photoswitches and using light as the trigger ("tethered photopharmacology"). Genetically encoded, tethered photopharmacology is a variant of optogenetics and could even play a role in medicine wherever gene therapy is viable. However, gene therapy may not be necessary if sufficiently selective tethering strategies that operate on wild-type receptors can be developed.
[Mh] Termos MeSH primário: Optogenética/métodos
Farmacologia/métodos
[Mh] Termos MeSH secundário: Seres Humanos
Fatores de Tempo
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171010
[Lr] Data última revisão:
171010
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170907
[St] Status:MEDLINE
[do] DOI:10.1021/acs.biochem.7b00687


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[PMID]:28864789
[Au] Autor:Persky AM; Wells MA; Sanders KA; Fiordalisi J; Downey C; Anksorus HN
[Ad] Endereço:Dr. Persky is Clinical Associate Professor, Eshleman School of Pharmacy, University of North Carolina at Chapel Hill; Mr. Wells is a PharmD candidate, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill; Dr. Sanders was a postdoctoral fellow at the Eshelman School of Pharmacy, U
[Ti] Título:Improving Dental Students' Long-Term Retention of Pharmacy Knowledge with "Medication Minutes".
[So] Source:J Dent Educ;81(9):1077-1084, 2017 Sep.
[Is] ISSN:1930-7837
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:A major challenge in foundational science courses in dental curricula is the application of information from the classroom to a clinical setting. To bridge this gap, the aim of this study was to increase students' learning in a foundational pharmacology course through increasing clinical relevance and using formative assessment. Second-year dental students in an introductory pharmacology course were presented material in a traditional basic science lecture format and in brief examples of pharmacy-generated clinical content (Medication Minutes). Short-term retention was assessed with a series of five post-class session, non-graded quizzes, each containing four questions: two knowledge-based (one from basic science material and one Medication Minute) and two application-based (one from basic science material and one Medication Minute). Ten knowledge-based (basic science material) questions and ten application-based (Medication Minutes) questions were included on exams throughout the semester. The primary outcome was to measure long-term retention using performance on these questions on an assessment the following semester. Additionally, the impact of student engagement on examination performance was evaluated based on the number of quizzes each student completed. Students who completed three or more quizzes (n=43, 53%) were designated as "highly engaged," while students who completed less than three quizzes (n=36, 44%) were defined as "less engaged." Two students (3%) were excluded for not completing the long-term assessment or not consenting to the study. On short-term retention measures, the students performed better on the Medication Minute (M=0.76) than basic science (M=0.58) (p<0.001) material; however, on the in-semester examinations, there was no difference in performance. On long-term retention measures, the students performed better on Medication Minute material (M=0.64) than basic science material (M=0.33) (p<0.001); this was true for both highly engaged and less-engaged students. These results suggest that teaching pharmacology in a clinical context yielded better long-term retention than teaching with a non-clinical focus.
[Mh] Termos MeSH primário: Educação em Odontologia/métodos
Farmacologia/educação
Retenção (Psicologia)
Estudantes de Odontologia
[Mh] Termos MeSH secundário: Fatores de Tempo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170929
[Lr] Data última revisão:
170929
[Sb] Subgrupo de revista:D; IM
[Da] Data de entrada para processamento:170903
[St] Status:MEDLINE
[do] DOI:10.21815/JDE.017.062


  10 / 7360 MEDLINE  
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[PMID]:28752535
[Au] Autor:Romero-Collado A; Raurell-Torreda M; Zabaleta-Del-Olmo E; Rascon-Hernan C; Homs-Romero E
[Ad] Endereço:Department of Nursing, University of Girona, Girona, Spain.
[Ti] Título:Nurse prescribing in Spain: The law and the curriculum.
[So] Source:Nurs Health Sci;19(3):373-380, 2017 Sep.
[Is] ISSN:1442-2018
[Cp] País de publicação:Australia
[La] Idioma:eng
[Ab] Resumo:In this cross-sectional study, we explored course content related to pharmacology and/or healthcare products and supplies in all nursing degree programs in Spain. Changes in nurse-prescribing legislation in Spain require that nurses take a certification course before prescribing over-the-counter products and medications. Using a cross-sectional descriptive study, between July and September 2014, the degree programs of all centers that offer a degree in nursing in Spain were examined, selecting those with course information available online. All centers offered at least one pharmacology course. One-third of the required courses had content related to pharmacology and healthcare products/supplies. The analysis showed that the course content and training received during the current nursing degree program provides the knowledge and skills needed to prescribe healthcare products/supplies and medications that do not now require a doctor's prescription, without the need for additional training and certification. It is essential that government regulation of nursing education be aligned with nursing competencies, curriculum standards, clinical practice, and evidence-based research to provide the maximum level of confidence for nursing professionals and their patients.
[Mh] Termos MeSH primário: Currículo
Educação em Enfermagem/métodos
Farmacologia/educação
Padrões de Prática em Enfermagem/legislação & jurisprudência
Escolas de Enfermagem/estatística & dados numéricos
[Mh] Termos MeSH secundário: Competência Clínica
Estudos Transversais
Seres Humanos
Espanha
[Pt] Tipo de publicação:JOURNAL ARTICLE; MULTICENTER STUDY
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170911
[Lr] Data última revisão:
170911
[Sb] Subgrupo de revista:IM; N
[Da] Data de entrada para processamento:170729
[St] Status:MEDLINE
[do] DOI:10.1111/nhs.12355



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