Base de dados : MEDLINE
Pesquisa : H01.158.782 [Categoria DeCS]
Referências encontradas : 12158 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 1216 ir para página                         

  1 / 12158 MEDLINE  
              next record last record
seleciona
para imprimir
Fotocópia
[PMID]:29297217
[Au] Autor:Musajo-Somma L; Musajo-Somma A
[Ti] Título:Medical Rejuvenation in Georgia in the past: the Sukhumi Station.
[So] Source:Vesalius;22(2 Suppl):59-66, 2016 Dec.
[Is] ISSN:1373-4857
[Cp] País de publicação:Belgium
[La] Idioma:eng
[Ab] Resumo:If youth and body appearance enhancement is as old as Homo Sapiens, reliable medical technology for such activities is only about 100 years old. At the dawn of the 20th century, surgical operations performed under the Voronoff's treatment plan (monkey gonads' tissue grafting into humans) or the Steinach's technique (vasoligation) offered a promise of longevity, beauty and therefore youth restoration. The many links with a newly recognized discipline, endocrinology, offer a critical insight on the strong interactions between medicine and surgery in the promise of successful antiaging. On the front-line of scientific research, the Institute of Experimental Endocrinology's primate station in Sukhumi (West Georgia, now Abkhazia, on the Black Sea coast) developed a leadership role in the medical research, including rejuvenation with testis' tissues. Authors focus their attention to the everlasting commitment to experimental and clinical research as developed by Sukhumi scholars and the related moral, practical and ideological implications.
[Mh] Termos MeSH primário: Fisiologia/história
Rejuvenescimento
[Mh] Termos MeSH secundário: Animais
Endocrinologia/história
República da Geórgia
Gônadas/cirurgia
Gônadas/transplante
Haplorrinos/cirurgia
História do Século XX
História do Século XXI
Seres Humanos
Masculino
Primatas/fisiologia
Primatas/cirurgia
Testículo/fisiologia
Testículo/cirurgia
U.R.S.S.
Vasectomia/história
[Pt] Tipo de publicação:BIOGRAPHY; HISTORICAL ARTICLE; JOURNAL ARTICLE; PORTRAITS
[Ps] Nome de pessoa como assunto:Ivanov I; Koltsov NK
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180212
[Lr] Data última revisão:
180212
[Sb] Subgrupo de revista:QIS
[Da] Data de entrada para processamento:180104
[St] Status:MEDLINE


  2 / 12158 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
[PMID]:29283535
[Au] Autor:Mazzocchi F
[Ti] Título:Could we gain insights from the past? Considerations on the 2015 Noble Prize in Physiology or Medicine.
[So] Source:Vesalius;22(2):15-23, 2016 Dec.
[Is] ISSN:1373-4857
[Cp] País de publicação:Belgium
[La] Idioma:eng
[Ab] Resumo:One of the winners of the 2015 Nobel Prize in Physiology or Medicine drew inspiration for her research from Traditional Chinese Medicine (TCM). Beginning with a brief history of such a research, some remarks are offered on the event. It is argued that two (however interacting) streams of TCM seem to coexist today in China: one that has embraced modernization and another one that has striven to preserve its distinctiveness with respect to entitled to contribute to medical pluralism.
[Mh] Termos MeSH primário: Medicina Tradicional Chinesa/métodos
Prêmio Nobel
Fisiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180212
[Lr] Data última revisão:
180212
[Sb] Subgrupo de revista:QIS
[Da] Data de entrada para processamento:171229
[St] Status:MEDLINE


  3 / 12158 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29195066
[Au] Autor:Sehgal A
[Ad] Endereço:Chronobiology Program, HHMI, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Electronic address: amita@pennmedicine.upenn.edu.
[Ti] Título:Physiology Flies with Time.
[So] Source:Cell;171(6):1232-1235, 2017 Nov 30.
[Is] ISSN:1097-4172
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The 2017 Nobel Prize in Medicine or Physiology has been awarded to Jeffrey Hall, Michael Rosbash, and Michael Young for elucidating molecular mechanisms of the circadian clock. From studies beginning in fruit flies, we now know that circadian regulation pervades most biological processes and has strong ties to human health and disease.
[Mh] Termos MeSH primário: Relógios Circadianos
Prêmio Nobel
Fisiologia/história
[Mh] Termos MeSH secundário: Animais
Proteínas CLOCK/metabolismo
História do Século XX
História do Século XXI
Seres Humanos
[Pt] Tipo de publicação:BIOGRAPHY; HISTORICAL ARTICLE; JOURNAL ARTICLE
[Ps] Nome de pessoa como assunto:Hall J; Rosbash M; Young M
[Nm] Nome de substância:
EC 2.3.1.48 (CLOCK Proteins)
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171222
[Lr] Data última revisão:
171222
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171202
[St] Status:MEDLINE


  4 / 12158 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28455381
[Au] Autor:Blair S
[Ti] Título:Eric Lewis Blair.
[So] Source:BMJ;357:j2021, 2017 04 28.
[Is] ISSN:1756-1833
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Colecistocinina/imunologia
Gastrinas/imunologia
Fisiologia/história
Secretina/imunologia
[Mh] Termos MeSH secundário: Bioensaio/métodos
Colecistocinina/isolamento & purificação
Gastrinas/isolamento & purificação
História do Século XX
Seres Humanos
Imunoensaio/métodos
Secretina/isolamento & purificação
Reino Unido
[Pt] Tipo de publicação:BIOGRAPHY; HISTORICAL ARTICLE; JOURNAL ARTICLE
[Ps] Nome de pessoa como assunto:Blair EL
[Nm] Nome de substância:
0 (Gastrins); 1393-25-5 (Secretin); 9011-97-6 (Cholecystokinin)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171128
[Lr] Data última revisão:
171128
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170430
[St] Status:MEDLINE
[do] DOI:10.1136/bmj.j2021


  5 / 12158 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29022943
[Au] Autor:Murphy KR; Park JH; Huber R; Ja WW
[Ad] Endereço:Department of Neuroscience, The Scripps Research Institute, Jupiter, Florida, USA.
[Ti] Título:Simultaneous measurement of sleep and feeding in individual Drosophila.
[So] Source:Nat Protoc;12(11):2355-2366, 2017 Nov.
[Is] ISSN:1750-2799
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Drosophila is widely used for the dissection of genetic and neuronal mechanisms of behavior. Recently, flies have emerged as a model for investigating the regulation of feeding and sleep. Although typically studied in isolation, increasing evidence points to a fundamental connection between these behaviors. Thus, a system for measuring sleep and feeding simultaneously in a single integrated system is important for interpreting behavioral shifts of either state. Here, we describe the construction and use of the Activity Recording Capillary Feeder or CAFE (ARC), a machine-vision (automated image tracking)-based system for the integrated measurement of sleep and feeding in individual Drosophila. Flies feed on liquid food from a microcapillary, and consumption is measured by tracking the liquid meniscus over time. Sleep measurements are obtained from positional tracking of individual animals, and arousal threshold can be determined by vibrational stimulus response. Using this system, a single computer and experimenter can track diverse behaviors from up to 60 individual flies in a single integrated system. The ARC is efficiently assembled with minimal training, and each experiment can be run for up to ∼7 d, with a total setup and breakdown time of ∼2 h.
[Mh] Termos MeSH primário: Drosophila melanogaster/fisiologia
Comportamento Alimentar/fisiologia
Fisiologia/métodos
Sono/fisiologia
[Mh] Termos MeSH secundário: Animais
Nível de Alerta/fisiologia
Modelos Teóricos
Software
Interface Usuário-Computador
Vibração
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171020
[Lr] Data última revisão:
171020
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171013
[St] Status:MEDLINE
[do] DOI:10.1038/nprot.2017.096


  6 / 12158 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28888322
[Au] Autor:Blenis J
[Ad] Endereço:Meyer Cancer Center and Department of Pharmacology, Weill Cornell Medicine, 413 East 69(th) Street, New York, NY 10021, USA. Electronic address: jblenis@med.cornell.edu.
[Ti] Título:TOR, the Gateway to Cellular Metabolism, Cell Growth, and Disease.
[So] Source:Cell;171(1):10-13, 2017 Sep 21.
[Is] ISSN:1097-4172
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Michael N. Hall is this year's recipient of the Lasker Basic Medical Research Award for the identification of the target of rapamycin, TOR. TOR is a master regulator of the cell's growth and metabolic state, and its dysregulation contributes to a variety of diseases, including diabetes, obesity, neurodegenerative disorders, aging, and cancer, making the TOR pathway an attractive therapeutic target.
[Mh] Termos MeSH primário: Distinções e Prêmios
Células/metabolismo
Fisiologia/história
Transdução de Sinais
Serina-Treonina Quinases TOR/fisiologia
[Mh] Termos MeSH secundário: Animais
Antifúngicos/química
Antifúngicos/isolamento & purificação
Antifúngicos/uso terapêutico
História do Século XX
Seres Humanos
Neoplasias/tratamento farmacológico
Sirolimo/química
Sirolimo/isolamento & purificação
Sirolimo/uso terapêutico
Suíça
[Pt] Tipo de publicação:BIOGRAPHY; HISTORICAL ARTICLE; JOURNAL ARTICLE
[Ps] Nome de pessoa como assunto:Hall MN
[Nm] Nome de substância:
0 (Antifungal Agents); EC 2.7.1.1 (TOR Serine-Threonine Kinases); W36ZG6FT64 (Sirolimus)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171010
[Lr] Data última revisão:
171010
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170911
[St] Status:MEDLINE


  7 / 12158 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28886375
[Au] Autor:Chomet P; Martienssen R
[Ad] Endereço:NRGene, 20 South Sarah St., St Louis, MO 63108, USA.
[Ti] Título:Barbara McClintock's Final Years as Nobelist and Mentor: A Memoir.
[So] Source:Cell;170(6):1049-1054, 2017 Sep 07.
[Is] ISSN:1097-4172
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:September 2, 2017, marks the 25 year after the passing of Dr. Barbara McClintock, geneticist and recipient of the 1983 Nobel Prize in Physiology or Medicine for her discovery of transposable elements in maize. This memoir focuses on the last years of her life-after the prize-and includes personal recollections of how she mentored young scientists and inspired the age of genetics, epigenetics, and genomics.
[Mh] Termos MeSH primário: Elementos de DNA Transponíveis
Genética/educação
[Mh] Termos MeSH secundário: Genes de Plantas
Genética/história
História do Século XX
Prêmio Nobel
Fisiologia/história
Zea mays/genética
[Pt] Tipo de publicação:BIOGRAPHY; HISTORICAL ARTICLE; JOURNAL ARTICLE; PORTRAITS
[Ps] Nome de pessoa como assunto:McClintock B
[Nm] Nome de substância:
0 (DNA Transposable Elements)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170926
[Lr] Data última revisão:
170926
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170909
[St] Status:MEDLINE


  8 / 12158 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28864791
[Au] Autor:Tain M; Schwartzstein R; Friedland B; Park SE
[Ad] Endereço:Ms. Tain is a DMD student, Harvard School of Dental Medicine; Dr. Schwartzstein is Ellen and Melvin Gordon Professor of Medical Education, Harvard Medical School; Dr. Friedland is Assistant Professor of Oral Medicine, Infection, and Immunity, Harvard School of Dental Medicine; and Dr. Park is Associ
[Ti] Título:Dental and Medical Students' Use and Perceptions of Learning Resources in a Human Physiology Course.
[So] Source:J Dent Educ;81(9):1091-1097, 2017 Sep.
[Is] ISSN:1930-7837
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The aim of this study was to determine the use and perceived utility of various learning resources available during the first-year Integrated Human Physiology course at the dental and medical schools at Harvard University. Dental and medical students of the Class of 2018 were surveyed anonymously online in 2015 regarding their use of 29 learning resources in this combined course. The learning resources had been grouped into four categories to discern frequency of use and perceived usefulness among the categories. The survey was distributed to 169 students, and 73 responded for a response rate of 43.2%. There was no significant difference among the learning resource categories in frequency of use; however, there was a statistically significant difference among categories in students' perceptions of usefulness. No correlation was found between frequency of use and perceived usefulness of each category. Students seemingly were not choosing the most useful resources for them. These results suggest that, in the current educational environment, where new technologies and self-directed learning are highly sought after, there remains a need for instructor-guided learning.
[Mh] Termos MeSH primário: Atitude
Educação em Odontologia
Educação Médica
Fisiologia/educação
Estudantes de Odontologia
Estudantes de Medicina
[Mh] Termos MeSH secundário: Feminino
Seres Humanos
Masculino
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170929
[Lr] Data última revisão:
170929
[Sb] Subgrupo de revista:D; IM
[Da] Data de entrada para processamento:170903
[St] Status:MEDLINE
[do] DOI:10.21815/JDE.017.063


  9 / 12158 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28818834
[Au] Autor:Goodman BE; Ikiugu MN
[Ad] Endereço:Division of Basic Biomedical Sciences, Sanford School of Medicine, University of South Dakota, Vermillion, South Dakota; and Barb.Goodman@usd.edu.
[Ti] Título:Designing and implementing a physiology course for a new doctoral occupational therapy program with student feedback.
[So] Source:Adv Physiol Educ;41(3):485-491, 2017 Sep 01.
[Is] ISSN:1522-1229
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Recently, the Occupational Therapy Department requested a custom-designed medical physiology course for the students in the new occupational therapy doctoral program. The first author, a physiologist with extensive experience in teaching both undergraduate preprofessional and medical students in human physiology, was recruited to design and implement the course. The course was designed to be consistent with the constructivist philosophy that guides the occupational therapy curriculum. The course was offered for the first time during fall/spring 2015/2016 and included both first- and second-year occupational therapy doctoral students. A number of anonymous assessment tools were used to evaluate students' perceptions regarding the effectiveness of various pedagogies used in the course in enhancing their learning. A summative course assessment survey with comments was used at the end of the course. This paper describes the model of course design and the student feedback, which generated some suggestions for improvement of the course. This approach in designing a new course for a new disciplinary group of students should be helpful to other faculty involved in developing courses for health career programs populated by students with variable physiology backgrounds and different educational needs. The final relevant feedback from the course would be to have the students evaluate the usefulness of the course to their future careers immediately following their certification examinations in a year or two and during their subsequent clinical experiences; however, that information will likely be more difficult to obtain.
[Mh] Termos MeSH primário: Currículo/normas
Educação de Pós-Graduação/métodos
Terapia Ocupacional/educação
Fisiologia/educação
[Mh] Termos MeSH secundário: Educação de Pós-Graduação/normas
Retroalimentação
Seres Humanos
Aprendizagem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171103
[Lr] Data última revisão:
171103
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170819
[St] Status:MEDLINE
[do] DOI:10.1152/advan.00078.2016


  10 / 12158 MEDLINE  
              first record previous record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28818833
[Au] Autor:Inouye CY; Bae CL; Hayes KN
[Ad] Endereço:Department of Biological Sciences, California State University, East Bay, Hayward, California; caron.inouye@csueastbay.edu.
[Ti] Título:Using whiteboards to support college students' learning of complex physiological concepts.
[So] Source:Adv Physiol Educ;41(3):478-484, 2017 Sep 01.
[Is] ISSN:1522-1229
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Research underscores the importance of retrieval-based practice and application of knowledge for meaningful learning. However, the didactic lecture format continues to persist in traditional university physiology courses. A strategy called whiteboarding, where students use handheld dry erase boards and work in small groups to actively retrieve, discuss, and apply concepts presented in the lecture, has the potential to address challenges associated with actively engaging students in science courses for greater learning. The purpose of this study was to empirically examine the potential benefits of whiteboarding for increasing students' understanding of animal physiology concepts. Student performance on physiology questions assessing concepts taught using lecture only vs. concepts taught using lecture and whiteboarding were compared within the term that whiteboarding was used, as well as across whiteboard and lecture-only terms taught by the same instructor. Results showed that when whiteboarding was incorporated in the course, student performance on items that assessed concepts corresponding to the whiteboarding activities were significantly higher compared with performance on items that assessed concepts taught through lecture only. These patterns in student performance were found within and across terms. Taken together, findings point to whiteboarding as an effective tool that can be integrated in traditional lecture courses to promote students' understanding of physiology.
[Mh] Termos MeSH primário: Educação/métodos
Fisiologia/educação
Universidades/normas
[Mh] Termos MeSH secundário: Animais
Compreensão
Educação/normas
Educação/tendências
Seres Humanos
Aprendizagem
Fenômenos Fisiológicos
Fisiologia/tendências
Estudantes
Universidades/tendências
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171103
[Lr] Data última revisão:
171103
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170819
[St] Status:MEDLINE
[do] DOI:10.1152/advan.00202.2016



página 1 de 1216 ir para página                         
   


Refinar a pesquisa
  Base de dados : MEDLINE Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde