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[PMID]:27561618
[Au] Autor:Dumas A
[Ad] Endereço:Institut Galien Paris-Sud, Université Paris-Sud, UMR CNRS 8612, Faculté de Pharmacie, 5 rue Jean-Baptiste Clément, 92296 Châtenay-Malabry Cedex, France. anaelle.dumas@u-psud.fr.
[Ti] Título:DMCCB Basel Symposium 2016 Macrocycles in Drug- and Agrochemical Discovery Symposium of the Division of Medicinal Chemistry and Chemical Biology (DMCCB) of the Swiss Chemical Society (SCS), Department of Chemistry, University of Basel, May 24(th), 2016.
[So] Source:Chimia (Aarau);70(7-8):561-2, 2016.
[Is] ISSN:0009-4293
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Mh] Termos MeSH primário: Agroquímicos/química
Química Agrícola/tendências
Química Farmacêutica/tendências
Compostos Macrocíclicos/química
[Mh] Termos MeSH secundário: Ciclização
Compostos Macrocíclicos/síntese química
[Pt] Tipo de publicação:CONGRESSES
[Nm] Nome de substância:
0 (Agrochemicals); 0 (Macrocyclic Compounds)
[Em] Mês de entrada:1701
[Cu] Atualização por classe:170113
[Lr] Data última revisão:
170113
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160827
[St] Status:MEDLINE
[do] DOI:10.2533/chimia.2016.561


  2 / 224 MEDLINE  
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[PMID]:27561617
[Au] Autor:Heinzelmann E
[Ad] Endereço:science and technology journalist.
[Ti] Título:Biocatalysis - Key Technology to Meet Global Challenges CCBIO Symposium at the 8(th) Waedenswil Day of Life Science.
[So] Source:Chimia (Aarau);70(7-8):557-60, 2016.
[Is] ISSN:0009-4293
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:In a world of dwindling fossil-based energy, global air pollution and warming, biocatalysis may be a perfect problem-solver. It has the potential to procure sustainable raw materials and energy from biomass, and enables chiral and highly functionalized compounds to be produced ecologically for the chemical and pharmaceutical industry. At ZHAW Waedenswil on June 20, 2016, the Competence Center for Biocatalysis (CCBIO) gave European experts the opportunity to present the latest findings from science, research and practice in the future-oriented field of biocatalysis.
[Mh] Termos MeSH primário: Biocatálise
Enzimas/química
[Mh] Termos MeSH secundário: Biomassa
Biotecnologia
Química Agrícola
Indústria Farmacêutica
[Pt] Tipo de publicação:CONGRESSES
[Nm] Nome de substância:
0 (Enzymes)
[Em] Mês de entrada:1701
[Cu] Atualização por classe:170113
[Lr] Data última revisão:
170113
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160827
[St] Status:MEDLINE
[do] DOI:10.2533/chimia.2016.557


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[PMID]:27487684
[Au] Autor:Nau JY
[Ti] Título:[Not Available].
[Ti] Título:MONSANTO DÉVORÉ PAR BAYER: EN QUOI CELA NOUS ÉCLAIRE..
[So] Source:Rev Med Suisse;12(521):1116-7, 2016 Jun 01.
[Is] ISSN:1660-9379
[Cp] País de publicação:Switzerland
[La] Idioma:fre
[Mh] Termos MeSH primário: Agricultura
Química Agrícola
Indústrias
[Mh] Termos MeSH secundário: Comércio
Alemanha
Seres Humanos
Pesquisa
Estados Unidos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1608
[Cu] Atualização por classe:160804
[Lr] Data última revisão:
160804
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160805
[St] Status:MEDLINE


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[PMID]:26746344
[Au] Autor:Jeanmart S
[Ad] Endereço:Syngenta Crop Protection Muenchwilen AG, WST-820.1.15, Schaffhauserstrasse, 4332 Stein, Switzerland. Electronic address: stephane.jeanmart@syngenta.com.
[Ti] Título:Recent developments in agrochemistry.
[So] Source:Bioorg Med Chem;24(3):315-6, 2016 Feb 01.
[Is] ISSN:1464-3391
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Química Agrícola
[Mh] Termos MeSH secundário: Abastecimento de Alimentos
Seres Humanos
[Pt] Tipo de publicação:EDITORIAL; INTRODUCTORY JOURNAL ARTICLE
[Em] Mês de entrada:1610
[Cu] Atualização por classe:161230
[Lr] Data última revisão:
161230
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160110
[St] Status:MEDLINE


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[PMID]:26577980
[Au] Autor:Jeschke P
[Ad] Endereço:Bayer CropScience AG, Small Molecules Research, Pest Control Chemistry, Monheim am Rhein, Germany.
[Ti] Título:Progress of modern agricultural chemistry and future prospects.
[So] Source:Pest Manag Sci;72(3):433-55, 2016 Mar.
[Is] ISSN:1526-4998
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Agriculture is facing an enormous challenge: it must ensure that enough high-quality food is available to meet the needs of a continually growing population. Current and future agronomic production of food, feed, fuel and fibre requires innovative solutions for existing and future challenges, such as climate change, resistance to pests, increased regulatory demands, renewable raw materials or requirements resulting from food chain partnerships. Modern agricultural chemistry has to support farmers to manage these tasks. Today, the so-called 'side effects' of agrochemicals regarding yield and quality are gaining more importance. Agrochemical companies with a strong research and development focus will have the opportunity to shape the future of agriculture by delivering innovative integrated solutions. This review gives a comprehensive overview of the innovative products launched over the past 10 years and describes the progress of modern agricultural chemistry and its future prospects.
[Mh] Termos MeSH primário: Agricultura/tendências
Química Agrícola/tendências
[Mh] Termos MeSH secundário: Agroquímicos/toxicidade
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Agrochemicals)
[Em] Mês de entrada:1610
[Cu] Atualização por classe:161230
[Lr] Data última revisão:
161230
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151119
[St] Status:MEDLINE
[do] DOI:10.1002/ps.4190


  6 / 224 MEDLINE  
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[PMID]:25517210
[Au] Autor:Liu C; Guan A; Yang J; Chai B; Li M; Li H; Yang J; Xie Y
[Ad] Endereço:State Key Laboratory of the Discovery and Development of Novel Pesticide, Shenyang Research Institute of Chemical Industry Company Ltd. , Shenyang 110021, China.
[Ti] Título:Efficient Approach To Discover Novel Agrochemical Candidates: Intermediate Derivatization Method.
[So] Source:J Agric Food Chem;64(1):45-51, 2016 Jan 13.
[Is] ISSN:1520-5118
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Intensive competition of intellectual property, easy development of agrochemical resistance, and stricter regulations of environmental concerns make the successful rate for agrochemical discovery extremely lower using traditional agrochemical discovery methods. Therefore, there is an urgent need to find a novel approach to guide agrochemical discovery with high efficiency to quickly keep pace with the changing market. On the basis of these situations, here we summarize the intermediate derivatization method (IDM) between conventional methods in agrochemicals and novel ones in pharmaceuticals. This method is relatively efficient with short time in discovery phase, reduced cost, especially good innovated structure, and better performance. In this paper, we summarize and illustrate "what is the IDM" and "why to use" and "how to use" it to accelerate the discovery of new biologically active molecules, focusing on agrochemicals. Furthermore, we display several research projects in our novel agrochemical discovery programs with improved success rate under guidance of this strategy in recent years.
[Mh] Termos MeSH primário: Agroquímicos/química
Química Agrícola/métodos
Extratos Vegetais/química
[Mh] Termos MeSH secundário: Estrutura Molecular
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Agrochemicals); 0 (Plant Extracts)
[Em] Mês de entrada:1608
[Cu] Atualização por classe:160113
[Lr] Data última revisão:
160113
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:141218
[St] Status:MEDLINE
[do] DOI:10.1021/jf5054707


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[PMID]:26025003
[Au] Autor:Turnipseed SB; Lohne JJ; Boison JO
[Ad] Endereço:U.S. Food and Drug Administration, Animal Drugs Research Center, Denver Federal Center, PO Box 25087, Denver, CO 80225, USA.
[Ti] Título:Review: Application of High Resolution Mass Spectrometry to Monitor Veterinary Drug Residues in Aquacultured Products.
[So] Source:J AOAC Int;98(3):550-8, 2015 May-Jun.
[Is] ISSN:1060-3271
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:High resolution MS (HRMS) instruments provide accurate mass measurements. With HRMS, virtually an unlimited number of compounds can be analyzed simultaneously because full-scan data are collected, rather than preselected ion transitions corresponding to specific compounds. This enables the development of methods that can monitor for a wide scope of residues and contaminants in aquacultured fish and shellfish including antibiotics, metabolites, and emerging contaminants. Applications of HRMS to the analysis of veterinary drug residues in aquacultured products are summarized in this review including methods for screening, quantifying, and identifying drug residues in these matrixes. The use of targeted, semi-targeted, and nontargeted analysis of HRMS data and the implications to the global aquaculture industry are also reviewed.
[Mh] Termos MeSH primário: Aquicultura/métodos
Inocuidade dos Alimentos
Legislação sobre Alimentos
[Mh] Termos MeSH secundário: Animais
Química Agrícola
Resíduos de Drogas/análise
Fertilizantes
Peixes
Drogas Veterinárias
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Fertilizers); 0 (Veterinary Drugs)
[Em] Mês de entrada:1509
[Cu] Atualização por classe:150619
[Lr] Data última revisão:
150619
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150531
[St] Status:MEDLINE
[do] DOI:10.5740/jaoacint.14-265


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[PMID]:26024870
[Au] Autor:Boison JO; Turnipseed SB
[Ad] Endereço:Canadian Food Inspection Agency (CFIA), Centre for Veterinary Dmg Residues (CVDR) Laboratory, 116 Veterinary Rd, Saskatoon SK, S7N 2R3.
[Ti] Título:A Review of Aquaculture Practices and Their Impacts on Chemical Food Safety from a Regulatory Perspective.
[So] Source:J AOAC Int;98(3):541-9, 2015 May-Jun.
[Is] ISSN:1060-3271
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Aquaculture is currently one of the most rapidly growing food production industries in the world. The increasing global importance for this industry stems primarily from the fact that it is reducing the gap between the supply and demand for fish products. Commercial aquaculture contributes significantly to the economies of many countries since high-value fish species are a major source of foreign exchange. This review looks at the aquaculture industry, the issues raised by the production of fish through aquaculture for food security, the sustainability of the practice to agriculture, what the future holds for the industry in the next 10-20 years, and why there is a need to have available analytical procedures to regulate the safe use of chemicals and veterinary drugs in aquaculture.
[Mh] Termos MeSH primário: Agricultura/métodos
Inocuidade dos Alimentos
Legislação sobre Alimentos
[Mh] Termos MeSH secundário: Animais
Química Agrícola
Fertilizantes
Peixes
Drogas Veterinárias
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Fertilizers); 0 (Veterinary Drugs)
[Em] Mês de entrada:1509
[Cu] Atualização por classe:150619
[Lr] Data última revisão:
150619
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150531
[St] Status:MEDLINE
[do] DOI:10.5740/jaoacint.15-033


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[PMID]:25715823
[Au] Autor:Lubkowski K; Smorowska A; Grzmil B; Kozlowska A
[Ad] Endereço:Institute of Chemical and Environment Engineering, West Pomeranian University of Technology, ul. Pulaskiego 10, 70-322 Szczecin, Poland.
[Ti] Título:Controlled-release fertilizer prepared using a biodegradable aliphatic copolyester of poly(butylene succinate) and dimerized fatty acid.
[So] Source:J Agric Food Chem;63(10):2597-605, 2015 Mar 18.
[Is] ISSN:1520-5118
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The preparation and characterization of a controlled-release multicomponent (NPK) fertilizer with the coating layer consisting of a biodegradable copolymer of poly(butylene succinate) and a butylene ester of dilinoleic acid (PBS/DLA) is reported. The morphology and structure of the resulting polymer-coated materials and the thickness of the covering layers were examined using X-ray diffraction and scanning electron microscopy coupled with energy dispersive X-ray analysis. The mechanical properties of these materials were determined with a strength-testing machine. Nutrient release was measured in water using spectrophotometry, potentiometry, and conductivity methods. The results of the nutrient release experiments from these polymer-coated materials were compared with the requirements for controlled-release fertilizers. A conceptual model is presented describing the mechanism of nutrient release from the materials prepared in this study. This model is based on the concentrations of mineral components inside the water-penetrated fertilizer granules, the diffusion properties of the nutrients in water, and a diffusion coefficient through the polymer layer. The experimental kinetic data on nutrient release were interpreted using the sigmoidal model equation developed in this study.
[Mh] Termos MeSH primário: Química Agrícola/métodos
Preparações de Ação Retardada/química
Ácidos Graxos/química
Fertilizantes/análise
Poliésteres/química
[Mh] Termos MeSH secundário: Alcenos/química
Dimerização
Cinética
Difração de Raios X
[Pt] Tipo de publicação:EVALUATION STUDIES; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Alkenes); 0 (Delayed-Action Preparations); 0 (Fatty Acids); 0 (Fertilizers); 0 (Polyesters); 25167-67-3 (butylene)
[Em] Mês de entrada:1510
[Cu] Atualização por classe:150318
[Lr] Data última revisão:
150318
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150227
[St] Status:MEDLINE
[do] DOI:10.1021/acs.jafc.5b00518


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[PMID]:25184275
[Au] Autor:Li M; Li P; Wu H; Zhang Q; Ma F; Zhang Z; Ding X; Wang H
[Ad] Endereço:Oil Crops Research Institute of the Chinese Academy of Agricultural Sciences, Wuhan, P. R. China; Key Laboratory of Detection for Mycotoxins, Ministry of Agriculture, Wuhan, P. R. China; Laboratory of Risk Assessment for Oilseeds Products (Wuhan), Ministry of Agriculture, Wuhan, P. R. China.
[Ti] Título:An ultra-sensitive monoclonal antibody-based competitive enzyme immunoassay for sterigmatocystin in cereal and oil products.
[So] Source:PLoS One;9(9):e106415, 2014.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Sterigmatocystin (STG), a biosynthesis precursor of aflatoxin B1, is well known for its toxic and carcinogenic effects in humans and animals. STG derivatives and protein conjugates are needed for generation of monoclonal antibodies (mAbs). This work describes a reliable and fast synthesis of novel STG derivatives, based on which novel STG bovine serum albumin conjugates were prepared. With the novel STG bovine serum albumin conjugates, three sensitive and specific mAbs against STG, named VerA 3, VerA 4, and VerA 6, were prepared by semi-solid hypoxanthine/aminopterin/thymidine (HAT) medium using a modified two-step screening procedure. They exhibited high affinity for STG and no cross-reactivity (CR) with aflatoxins B1, B2, G1, G2, and M1. Based on the most sensitive antibody VerA 3, an ultra-sensitive competitive enzyme-linked immunosorbent assay (ELISA) was developed for STG in wheat, maize, and peanuts. Assays were performed in the STG-GA-BSA-coated (0.5 µg · mL(-1)) ELISA format, in which the antibody was diluted to 1:80,000. Several physicochemical factors influencing assay performance, such as pH, ionic strength, blocking solution, and diluting solution, were optimized. The final results showed that the assays had the detection limits of 0.08 ng · g(-1) for wheat, 0.06 ng · g(-1) for maize, and 0.1 ng · g(-1) for peanuts, inter-assay and intra-assay variations of less than 10%, and recoveries ranging from 83% to 110%. These recoveries were in good agreement with those obtained by using HPLC-MS/MS method (90-104%), indicating the importance of the mAb VerA 3 in the study of STG in crude agricultural products.
[Mh] Termos MeSH primário: Aflatoxina B1/isolamento & purificação
Anticorpos Monoclonais/química
Técnicas Imunoenzimáticas/métodos
Esterigmatocistina/isolamento & purificação
[Mh] Termos MeSH secundário: Aflatoxina B1/química
Aflatoxina B1/toxicidade
Anticorpos Monoclonais/imunologia
Química Agrícola
Grãos Comestíveis/química
Análise de Alimentos
Seres Humanos
Óleos/química
Soroalbumina Bovina/química
Soroalbumina Bovina/imunologia
Esterigmatocistina/química
Esterigmatocistina/imunologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Antibodies, Monoclonal); 0 (Oils); 10048-13-2 (Sterigmatocystin); 27432CM55Q (Serum Albumin, Bovine); 9N2N2Y55MH (Aflatoxin B1)
[Em] Mês de entrada:1505
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140904
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0106415



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