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Pesquisa : H02.070 [Categoria DeCS]
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[PMID]:29400044
[Au] Autor:Vincent C
[Ti] Título:[The Bell Labs contributions to (singing) voice enginee­ring].
[So] Source:Rev Laryngol Otol Rhinol (Bord);136(5):193-6, 2015.
[Is] ISSN:0035-1334
[Cp] País de publicação:France
[La] Idioma:fre
[Ab] Resumo:While in «art¼ and «traditional¼ music, the nimbleness of the voice and the mastering of the vocal tone are put into pers­pective, in «popular¼ music, sound engineering takes the lead, and relegates the vocal virtuosity of the interpreter to second place. We propose to study here three technologies with contri­butions to music. All are developed and patented by the Bell Labs: The artificial larynx (and its derivatives, Sonovox and TalkBox), the vocoder and the speech synthesis. After a presen­tation of the source-filter theory, vital to these innovations, the principle of these three technologies is explained. A brief historical is outlined and is complemented by examples of films and musical selections depicting these processes. In light of these elements, we conclude: Sound engineering, and in parti­cular the modification of voice sonority, has become an indis­pensable component in the process of «pop¼ artistic musical creation.
[Mh] Termos MeSH primário: Laringe Artificial
Canto
[Mh] Termos MeSH secundário: Engenharia Biomédica
Seres Humanos
Laringectomia/reabilitação
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180206
[St] Status:MEDLINE


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[PMID]:29026204
[Au] Autor:Mitchell MJ; Jain RK; Langer R
[Ad] Endereço:Department of Bioengineering, University of Pennsylvania, 240 Skirkanich Hall, 210 S. 33rd Street, Philadelphia, Pennsylvania 19104, USA.
[Ti] Título:Engineering and physical sciences in oncology: challenges and opportunities.
[So] Source:Nat Rev Cancer;17(11):659-675, 2017 Nov.
[Is] ISSN:1474-1768
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The principles of engineering and physics have been applied to oncology for nearly 50 years. Engineers and physical scientists have made contributions to all aspects of cancer biology, from quantitative understanding of tumour growth and progression to improved detection and treatment of cancer. Many early efforts focused on experimental and computational modelling of drug distribution, cell cycle kinetics and tumour growth dynamics. In the past decade, we have witnessed exponential growth at the interface of engineering, physics and oncology that has been fuelled by advances in fields including materials science, microfabrication, nanomedicine, microfluidics, imaging, and catalysed by new programmes at the National Institutes of Health (NIH), including the National Institute of Biomedical Imaging and Bioengineering (NIBIB), Physical Sciences in Oncology, and the National Cancer Institute (NCI) Alliance for Nanotechnology. Here, we review the advances made at the interface of engineering and physical sciences and oncology in four important areas: the physical microenvironment of the tumour and technological advances in drug delivery; cellular and molecular imaging; and microfluidics and microfabrication. We discussthe research advances, opportunities and challenges for integrating engineering and physical sciences with oncology to develop new methods to study, detect and treat cancer, and we also describe the future outlook for these emerging areas.
[Mh] Termos MeSH primário: Engenharia Biomédica
Oncologia
Disciplinas das Ciências Naturais
Neoplasias/diagnóstico
Neoplasias/terapia
[Mh] Termos MeSH secundário: Animais
Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171115
[Lr] Data última revisão:
171115
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171014
[St] Status:MEDLINE
[do] DOI:10.1038/nrc.2017.83


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[PMID]:28445451
[Au] Autor:Bourzac K
[Ti] Título:Bioengineering: Solar upgrade.
[So] Source:Nature;544(7651):S11-S13, 2017 04 26.
[Is] ISSN:1476-4687
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Bioengenharia
Engenharia Biomédica
[Mh] Termos MeSH secundário: Fatores de Risco
[Pt] Tipo de publicação:JOURNAL ARTICLE; COMMENT
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170714
[Lr] Data última revisão:
170714
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170427
[St] Status:MEDLINE
[do] DOI:10.1038/544S11a


  4 / 10633 MEDLINE  
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[PMID]:28328495
[Au] Autor:Wilson BS
[Ti] Título:The Modern Cochlear Implant: A Triumph of Biomedical Engineering and the First Substantial Restoration of Human Sense Using a Medical Intervention.
[So] Source:IEEE Pulse;8(2):29-32, 2017 Mar-Apr.
[Is] ISSN:2154-2317
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Even as recently as the mid-1980s, many experts in otology and auditory science thought that restoration of useful hearing with crude and pervasive electrical stimulation of the cochlea was a fool's dream. The esteemed Prof. Rainer Klinke from Frankfurt (Figure 1) was among the chorus of critics, asserting in 1978 that "from a physiological point of view, cochlear implants will not work." Many others made similar categorical statements.
[Mh] Termos MeSH primário: Engenharia Biomédica
Implantes Cocleares
Perda Auditiva
[Mh] Termos MeSH secundário: Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170428
[Lr] Data última revisão:
170428
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170323
[St] Status:MEDLINE
[do] DOI:10.1109/MPUL.2017.2649039


  5 / 10633 MEDLINE  
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[PMID]:28320154
[Au] Autor:Portaro S; Russo M; Naro A; Bramanti A; Bramanti P; Rodolico C; Calabrò RS
[Ad] Endereço:IRCCS Centro Neurolesi "Bonino-Pulejo", Messina, Italy.
[Ti] Título:Advances in assessing myotonia: Can sensor-engineered glove have a role?
[So] Source:J Neurol Sci;375:3-7, 2017 Apr 15.
[Is] ISSN:1878-5883
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Non-dystrophic (NDMs) and Dystrophic Myotonias (DMs) are diseases characterized by the presence of myotonia with or without muscle weakness. A standardized myotonia assessment is important to more objectively quantify the handgrip myotonia. We screened 10 patients affected by NDM and 10 patients with DM, using the sensor-engineered glove (SEG). The time required to perform a complete finger extension (grip myotonia time, GMT) at maximum velocity (MV) after maximum voluntary contraction (MVC) was evaluated through an ad hoc protocol including rest, exercise, and ice effects on handgrip myotonia. We observed a general trend to GMT increase when applying the ice block and a GMT decrease when repeating GM movements, at individual level in both NDM and DM patients. SEG is an automated, non-invasive, quick, and easy technique for evaluating handgrip myotonia in NDM and DM patients. SEG could, therefore, be considered a promising tool to evaluate myotonia and monitor treatment efficacy for clinical trials.
[Mh] Termos MeSH primário: Engenharia Biomédica/métodos
Técnicas de Diagnóstico Neurológico/instrumentação
Força da Mão/fisiologia
Contração Muscular/fisiologia
Miotonia/diagnóstico
Miotonia/fisiopatologia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Equipamentos e Provisões
Feminino
Seres Humanos
Masculino
Meia-Idade
Músculo Esquelético/fisiopatologia
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170703
[Lr] Data última revisão:
170703
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170322
[St] Status:MEDLINE


  6 / 10633 MEDLINE  
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[PMID]:28181302
[Au] Autor:Bluestein D
[Ad] Endereço:Department of Biomedical Engineering, Stony Brook University, Stony Brook, NY, 11794-8181, USA.
[Ti] Título:Utilizing Computational Fluid Dynamics in Cardiovascular Engineering and Medicine-What You Need to Know. Its Translation to the Clinic/Bedside.
[So] Source:Artif Organs;41(2):117-121, 2017 Feb.
[Is] ISSN:1525-1594
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Engenharia Biomédica/métodos
Hemodinâmica
Hidrodinâmica
[Mh] Termos MeSH secundário: Simulação por Computador
Seres Humanos
Modelos Cardiovasculares
[Pt] Tipo de publicação:EDITORIAL
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170216
[Lr] Data última revisão:
170216
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170210
[St] Status:MEDLINE
[do] DOI:10.1111/aor.12914


  7 / 10633 MEDLINE  
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[PMID]:28162776
[Au] Autor:Costa E Silva JA; Steffen RE
[Ad] Endereço:PUC-RJ Medical School; Brazilian Brain Institute.
[Ti] Título:The future of psychiatry: brain devices.
[So] Source:Metabolism;69S:S8-S12, 2017 Apr.
[Is] ISSN:1532-8600
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Recent advances in deep brain stimulators and brain-machine interfaces have greatly expanded the possibilities of neuroprosthetics and neuromodulation. Together with advances in neuroengineering, nanotechnology, molecular biology and material sciences, it is now possible to address fundamental questions in neuroscience in new, more powerful ways. It is now possible to apply these new technologies in ways that range from augmenting and restoring function to neuromodulation modalities that treat neuropsychiatric disorders. Recent developments in neuromodulation methods offer significant advantages and potential clinical benefits for a variety of disorders. Here we describe the current state of the art in neuromodulation methods, and some advances in brain-machine interfaces, describing the advantages and limitations of the clinical applications of each method. The future applications of these new methods and how they will shape the future of psychiatry and medicine, along with safety and ethical implications, are also discussed.
[Mh] Termos MeSH primário: Neuropatologia/métodos
Neuropsiquiatria/métodos
Neurociências/métodos
Psiquiatria/métodos
Transtornos Psicóticos/terapia
Terapias em Estudo/instrumentação
[Mh] Termos MeSH secundário: Estimulação Acústica/efeitos adversos
Estimulação Acústica/métodos
Estimulação Acústica/tendências
Animais
Engenharia Biomédica/métodos
Engenharia Biomédica/tendências
Interfaces Cérebro-Computador/efeitos adversos
Interfaces Cérebro-Computador/tendências
Estimulação Encefálica Profunda/efeitos adversos
Estimulação Encefálica Profunda/instrumentação
Estimulação Encefálica Profunda/tendências
Seres Humanos
Neuropatologia/tendências
Neuropsiquiatria/tendências
Neurociências/tendências
Psiquiatria/tendências
Transtornos Psicóticos/patologia
Transtornos Psicóticos/fisiopatologia
Terapias em Estudo/efeitos adversos
Terapias em Estudo/tendências
Estimulação Magnética Transcraniana/efeitos adversos
Estimulação Magnética Transcraniana/tendências
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170515
[Lr] Data última revisão:
170515
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170207
[St] Status:MEDLINE


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[PMID]:28161832
[Au] Autor:Laranjeira M; Shirosaki Y; Yoshimatsu Yasutomi S; Miyazaki T; Monteiro FJ
[Ad] Endereço:i3S, Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal. msl@ineb.up.pt.
[Ti] Título:Enhanced biosafety of silica coated gadolinium based nanoparticles.
[So] Source:J Mater Sci Mater Med;28(3):46, 2017 Mar.
[Is] ISSN:1573-4838
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:One of the most important and novel approaches of biomedical engineering is the development of new, effective and non-invasive medical diagnosis abilities, and treatments that have such requirements as advanced technologies for tumor imaging. Gadolinium (Gd) compounds can be used as MRI contrast agents, however the release of Gd ions presents some adverse side effects such as renal failure, pancreatitis or local necrosis. The main aim of the work was the development and optimization of Gadolinium based nanoparticles coated with silica to be used as bioimaging agent. Gd based nanoparticles were prepared through a precipitation method and afterwards, these nanoparticles were covered with silica, using Stöber method with ammonia and functionalized with 3-Aminopropyltriethoxysilane (APTES). Results showed that nanoparticles were homogeneous regarding chemical composition, silica layer thickness, total size and morphology. Also, silica coating was successfully not degraded after 4 weeks at pH 5.5, 6.0 and 7.4, contrary to GdOHCO nanoparticles that degraded. Regarding the in vitro cell tests, very good cell proliferation and viability were observed. In conclusion, the results showed that Gd based nanoparticles coated with silica for imaging applications were successfully obtained under a well-controlled method. Furthermore, silica coating may enhance magnetic nanoparticles biosafety because it avoids GdOHCO degradation into harmful products (such as Gd ions) at physiological conditions.
[Mh] Termos MeSH primário: Gadolínio/química
Nanopartículas Metálicas/química
Nanotecnologia/métodos
Dióxido de Silício/química
[Mh] Termos MeSH secundário: Engenharia Biomédica
Proliferação Celular
Sobrevivência Celular
Meios de Contraste/química
Fibroblastos/metabolismo
Seres Humanos
Concentração de Íons de Hidrogênio
L-Lactato Desidrogenase/metabolismo
Imagem por Ressonância Magnética
Nanopartículas de Magnetita/química
Microscopia Eletrônica de Transmissão
Necrose/tratamento farmacológico
Pancreatite/tratamento farmacológico
Propilaminas/química
Insuficiência Renal/tratamento farmacológico
Silanos/química
Espectroscopia de Infravermelho com Transformada de Fourier
Temperatura Ambiente
Difração de Raios X
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Contrast Media); 0 (Magnetite Nanoparticles); 0 (Propylamines); 0 (Silanes); 7631-86-9 (Silicon Dioxide); AU0V1LM3JT (Gadolinium); EC 1.1.1.27 (L-Lactate Dehydrogenase); L8S6UBW552 (amino-propyl-triethoxysilane)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:171021
[Lr] Data última revisão:
171021
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170206
[St] Status:MEDLINE
[do] DOI:10.1007/s10856-017-5855-1


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[PMID]:28141948
[Au] Autor:McKetta JJ; Truskett TM
[Ad] Endereço:Joe C. Walter, Jr. Chair Emeritus in Engineering, McKetta Department of Chemical Engineering, University of Texas at Austin, Austin, Texas 78712.
[Ti] Título:A Conversation with John McKetta.
[So] Source:Annu Rev Chem Biomol Eng;8:1-11, 2017 Jun 07.
[Is] ISSN:1947-5446
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:John J. McKetta, Jr. is a foundational figure in chemical engineering education and energy policy in the United States. An authority on the thermodynamic properties of hydrocarbons and an energy adviser to several US presidents, McKetta helped to educate and mentor thousands of students at the University of Texas at Austin for over 40 years, many of whom became leading figures in the energy and petrochemical industries, as well as in academia. As dean of the College of Engineering, McKetta helped to establish a bioengineering program, which later became the Biomedical Engineering Department, at the University of Texas at Austin, and was a tireless advocate for excellence and a focus on the student. At age 100, McKetta recalls the challenges and opportunities he faced in childhood, his memories of the emergence of petrochemical engineering, and his views on chemical engineering education and the people it has impacted in the United States over the past 100 years.
[Mh] Termos MeSH primário: Bioengenharia/educação
Engenharia Biomédica/educação
Engenharia Química/educação
[Mh] Termos MeSH secundário: Bioengenharia/história
Engenharia Biomédica/história
Engenharia Química/história
História do Século XX
História do Século XXI
Seres Humanos
Hidrocarbonetos/análise
Liderança
Indústria de Petróleo e Gás/educação
Indústria de Petróleo e Gás/história
Petróleo/análise
Texas
Estados Unidos
Universidades
[Pt] Tipo de publicação:BIOGRAPHY; HISTORICAL ARTICLE; INTERVIEW
[Ps] Nome de pessoa como assunto:McKetta J
[Nm] Nome de substância:
0 (Hydrocarbons); 0 (Petroleum)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170727
[Lr] Data última revisão:
170727
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170201
[St] Status:MEDLINE
[do] DOI:10.1146/annurev-chembioeng-060816-101315


  10 / 10633 MEDLINE  
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[PMID]:28112048
[Au] Autor:Budzik G; Turek P; Traciak J
[Ad] Endereço:1 Department of Mechanical Engineering, Faculty of Mechanical Engineering and Aeronautics, Rzeszów University of Technology, Rzeszów, Poland.
[Ti] Título:The influence of change in slice thickness on the accuracy of reconstruction of cranium geometry.
[So] Source:Proc Inst Mech Eng H;231(3):197-202, 2017 Mar.
[Is] ISSN:2041-3033
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The article presents a comparative study of change in slice thickness on the accuracy of reconstruction of cranium geometry. Research was performed on 10 different patients. Digital Imaging and Communications in Medicine data were obtained on the Siemens Somatom Sensation Open 40 scanner. At the stage of reconstruction, the same parameters were utilized, while only slice thickness was changed. Modeling with voxel dimensions of 0.4 mm × 0.4 mm × 2.4 mm was chosen as the gold standard over the modeling approach comprising voxel dimensions of 0.4 mm × 0.4 mm × 4.8 mm. The influence of layer thickness on the accuracy of cranium geometry is very similar for the 10 presented patients. The average results show a distribution with a positive skew and kurtosis. The value of skewness is 0.284 (small asymmetry) and kurtosis is 3.746 (a distribution more peaked). Based on 95% confidence, the changes in layer thickness from 2.4 to 4.8 mm generated errors reconstructing the geometry of the cranium by 0.516 mm ± 1.345 mm. The presented research highlights new opportunities to control deviations at the stage of data processing and modeling geometry of the cranium.
[Mh] Termos MeSH primário: Crânio/anatomia & histologia
[Mh] Termos MeSH secundário: Algoritmos
Engenharia Biomédica
Simulação por Computador
Seres Humanos
Processamento de Imagem Assistida por Computador
Imagem Tridimensional
Modelos Anatômicos
Imagens de Fantasmas
Tomografia Computadorizada por Raios X
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170823
[Lr] Data última revisão:
170823
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170124
[St] Status:MEDLINE
[do] DOI:10.1177/0954411916688717



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