Base de dados : MEDLINE
Pesquisa : H02.269 [Categoria DeCS]
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  1 / 4242 MEDLINE  
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[PMID]:29365301
[Au] Autor:Wright AA; Katz IT
[Ad] Endereço:Drs. Wright and Katz are national correspondents for the Journal.
[Ti] Título:Beyond Burnout - Redesigning Care to Restore Meaning and Sanity for Physicians.
[So] Source:N Engl J Med;378(4):309-311, 2018 Jan 25.
[Is] ISSN:1533-4406
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Pessoal Técnico de Saúde
Esgotamento Profissional
Assistência à Saúde/organização & administração
Médicos/psicologia
Carga de Trabalho
[Mh] Termos MeSH secundário: Colorado
Eficiência
Eficiência Organizacional
Registros Eletrônicos de Saúde
Docentes de Medicina
Feminino
Administração de Serviços de Saúde
Seres Humanos
Satisfação no Emprego
Liderança
Masculino
Equipe de Assistência ao Paciente
Fatores Sexuais
Estados Unidos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180208
[Lr] Data última revisão:
180208
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180125
[St] Status:MEDLINE
[do] DOI:10.1056/NEJMp1716845


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[PMID]:28892479
[Au] Autor:Pennington PM; Juárez JG; Arrivillaga MR; De Urioste-Stone SM; Doktor K; Bryan JP; Escobar CY; Cordón-Rosales C
[Ad] Endereço:Center for Health Studies, Universidad del Valle de Guatemala, Guatemala City, Guatemala.
[Ti] Título:Towards Chagas disease elimination: Neonatal screening for congenital transmission in rural communities.
[So] Source:PLoS Negl Trop Dis;11(9):e0005783, 2017 Sep.
[Is] ISSN:1935-2735
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Chagas disease is a neglected tropical disease that continues to affect populations living in extreme poverty in Latin America. After successful vector control programs, congenital transmission remains as a challenge to disease elimination. We used the PRECEDE-PROCEED planning model to develop strategies for neonatal screening of congenital Chagas disease in rural communities of Guatemala. These communities have persistent high triatomine infestations and low access to healthcare. We used mixed methods with multiple stakeholders to identify and address maternal-infant health behaviors through semi-structured interviews, participatory group meetings, archival reviews and a cross-sectional survey in high risk communities. From December 2015 to April 2016, we jointly developed a strategy to illustratively advertise newborn screening at the Health Center. The strategy included socioculturally appropriate promotional and educational material, in collaboration with midwives, nurses and nongovernmental organizations. By March 2016, eight of 228 (3.9%) pregnant women had been diagnosed with T. cruzi at the Health Center. Up to this date, no neonatal screening had been performed. By August 2016, seven of eight newborns born to Chagas seropositive women had been parasitologically screened at the Health Center, according to international standards. Thus, we implemented a successful community-based neonatal screening strategy to promote congenital Chagas disease healthcare in a rural setting. The success of the health promotion strategies developed will depend on local access to maternal-infant services, integration with detection of other congenital diseases and reliance on community participation in problem and solution definition.
[Mh] Termos MeSH primário: Doença de Chagas/congênito
Doença de Chagas/epidemiologia
Erradicação de Doenças
Transmissão Vertical de Doença Infecciosa/prevenção & controle
Triagem Neonatal
[Mh] Termos MeSH secundário: Doença de Chagas/prevenção & controle
Doença de Chagas/transmissão
Estudos Transversais
Guatemala/epidemiologia
Administração de Serviços de Saúde
Seres Humanos
Recém-Nascido
Entrevistas como Assunto
População Rural
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171031
[Lr] Data última revisão:
171031
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170912
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pntd.0005783


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[PMID]:28662054
[Au] Autor:Nana-Djeunga HC; Tchouakui M; Njitchouang GR; Tchatchueng-Mbougua JB; Nwane P; Domche A; Bopda J; Mbickmen-Tchana S; Akame J; Tarini A; Epée E; Biholong BD; Zhang Y; Tougoue JJ; Kabore A; Njiokou F; Kamgno J
[Ad] Endereço:Centre for Research on Filariasis and other Tropical Diseases, Yaoundé, Cameroon.
[Ti] Título:First evidence of lymphatic filariasis transmission interruption in Cameroon: Progress towards elimination.
[So] Source:PLoS Negl Trop Dis;11(6):e0005633, 2017 Jun.
[Is] ISSN:1935-2735
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Lymphatic filariasis (LF) is among the 10 neglected tropical diseases targeted for control or elimination by 2020. For LF elimination, the World Health Organization (WHO) has proposed a comprehensive strategy including (i) interruption of LF transmission through large-scale annual treatment (or mass drug administration (MDA)) of all eligible individuals in endemic areas, and (ii) alleviation of LF-associated suffering through morbidity management and disability prevention. In Cameroon, once-yearly mass administration of ivermectin and albendazole has been implemented since 2008. The aim of this study was to assess progress towards the elimination goal, looking specifically at the impact of six rounds of MDA on LF transmission in northern Cameroon. METHODOLOGY: The study was conducted in the North and Far North Regions of Cameroon. Five health districts that successfully completed six rounds of MDA (defined as achieving a treatment coverage ≥ 65% each year) and reported no positive results for Wuchereria bancrofti microfilariaemia during routine surveys following the fifth MDA were grouped into three evaluation units (EU) according to WHO criteria. LF transmission was assessed through a community-based transmission assessment survey (TAS) using an immunochromatographic test (ICT) for the detection of circulating filarial antigen (CFA) in children aged 5-8 years old. PRINCIPAL FINDINGS: A total of 5292 children (male/female ratio 1.04) aged 5-8 years old were examined in 97 communities. Positive CFA results were observed in 2, 8 and 11 cases, with a CFA prevalence of 0.13% (95% CI: 0.04-0.46) in EU#1, 0.57% (95% CI: 0.32-1.02) in EU#2, and 0.45% (95% CI: 0.23-0.89) in EU#3. CONCLUSION/SIGNIFICANCE: The positive CFA cases were below WHO defined critical cut-off thresholds for stopping treatment and suggest that transmission can no longer be sustained. Post-MDA surveillance activities should be organized to evaluate whether recrudescence can occur.
[Mh] Termos MeSH primário: Controle de Doenças Transmissíveis/métodos
Erradicação de Doenças
Transmissão de Doença Infecciosa/prevenção & controle
Filariose Linfática/prevenção & controle
Filariose Linfática/transmissão
Filaricidas/administração & dosagem
Administração de Serviços de Saúde
[Mh] Termos MeSH secundário: Albendazol/administração & dosagem
Animais
Antígenos de Helmintos/sangue
Camarões/epidemiologia
Criança
Pré-Escolar
Filariose Linfática/epidemiologia
Feminino
Seres Humanos
Imunocromatografia
Ivermectina/administração & dosagem
Masculino
Wuchereria bancrofti/isolamento & purificação
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antigens, Helminth); 0 (Filaricides); 70288-86-7 (Ivermectin); F4216019LN (Albendazole)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170720
[Lr] Data última revisão:
170720
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170630
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pntd.0005633


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[PMID]:28485716
[Au] Autor:Milevska Kostova N; Chichevalieva S; Ponce NA; van Ginneken E; Winkelmann J
[Ad] Endereço:Centre for Regional Policy Research and Cooperation Studiorum.
[Ti] Título:The former Yugoslav Republic of Macedonia: Health System Review.
[So] Source:Health Syst Transit;19(3):1-160, 2017 May.
[Is] ISSN:1817-6127
[Cp] País de publicação:Denmark
[La] Idioma:eng
[Ab] Resumo:This analysis of the health system of the former Yugoslav Republic of Macedonia reviews recent developments in organization and governance, health financing, health care provision, health reforms and health system performance. The country has made important progress during its transition from a socialist system to a market-based system, particularly in reforming the organization, financing and delivery of health care and establishing a mix of private and public providers. Though total health care expenditure has risen in absolute terms in recent decades, it has consistently fallen as share of GDP, and high levels of private health expenditure remain. Despite this, the health of the population has improved over the last decades, with life expectancy and mortality rates for both adults and children reaching similar levels to those in ex-communist EU countries, though death rates caused by unhealthy behaviour remain high. Inheriting a large health infrastructure, good public health services and well-distributed health service coverage after independence in 1991, the country re-built a social health insurance system with a broad benefit package. Primary care providers were privatized and new private hospitals were allowed to enter the market. In recent years, the country reformed the organization of care delivery to better incorporate both public and private providers in an integrated system. Significant efficiency gains were reached with a pioneering health information system that has reduced waiting times and led to a better coordination of care. This multi-modular e-health system has the potential to further reduce existing inefficiencies and to generate evidence for assessment and research. Despite this progress, satisfaction with health care delivery is very mixed with low satisfaction levels with public providers. The public hospital sector in particular is characterized by inefficient organization, financing and provision of health care; and many professionals move to other countries and to the private sector. Future challenges include sustainable planning and management of human resources as well as enhancing quality and efficiency of care through reform of hospital financing and organization.
[Mh] Termos MeSH primário: Assistência à Saúde/organização & administração
Reforma dos Serviços de Saúde/organização & administração
Administração de Serviços de Saúde
Qualidade da Assistência à Saúde
[Mh] Termos MeSH secundário: Assistência à Saúde/economia
Gastos em Saúde/estatística & dados numéricos
Serviços de Saúde/economia
Financiamento da Assistência à Saúde
Seres Humanos
Seguro Saúde/organização & administração
Macedônia (República)
Privatização
Telemedicina/organização & administração
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171113
[Lr] Data última revisão:
171113
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170510
[St] Status:MEDLINE


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[PMID]:28248694
[Au] Autor:Myers CG; Pronovost PJ
[Ad] Endereço:C.G. Myers is assistant professor, Carey Business School, Johns Hopkins University, and core faculty, Armstrong Institute for Patient Safety and Quality, Johns Hopkins Medicine, Baltimore, Maryland. P.J. Pronovost is senior vice president for patient safety and quality, Johns Hopkins Medicine, director, Armstrong Institute for Patient Safety and Quality, Johns Hopkins Medicine, and professor, Department of Anesthesiology and Critical Care Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland.
[Ti] Título:Making Management Skills a Core Component of Medical Education.
[So] Source:Acad Med;92(5):582-584, 2017 May.
[Is] ISSN:1938-808X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Physicians are being called upon to engage in greater leadership and management in increasingly complex and dynamic health care organizations. Yet, management skills are largely undeveloped in medical education. Without formal management training in the medical curriculum, physicians are left to cultivate their leadership and management abilities through a haphazard array of training programs or simply through trial and error, with consequences that may range from frustration among staff to reduced quality of care and increased risk of patient harm. To address this issue, the authors posit that medical education needs a more systematic focus on topics related to management and organization, such as individual decision making, interpersonal communication, team knowledge sharing, and organizational culture. They encourage medical schools to partner with business school faculty or other organizational scholars to offer a "Management 101" course in the medical curriculum to provide physicians-in-training with an understanding of these topics and raise the quality of physician leadership and management in modern health care organizations.
[Mh] Termos MeSH primário: Educação Médica/métodos
Administração de Serviços de Saúde
Liderança
Diretores Médicos/educação
Competência Profissional
[Mh] Termos MeSH secundário: Comunicação
Currículo
Tomada de Decisões
Seres Humanos
Cultura Organizacional
[Pt] Tipo de publicação:EDITORIAL
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170731
[Lr] Data última revisão:
170731
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170302
[St] Status:MEDLINE
[do] DOI:10.1097/ACM.0000000000001627


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[PMID]:28234987
[Au] Autor:Nolte S; Osborne RH; Dwinger S; Elsworth GR; Conrad ML; Rose M; Härter M; Dirmaier J; Zill JM
[Ad] Endereço:Department of Psychosomatic Medicine, Center for Internal Medicine and Dermatology, Charité-Universitätsmedizin Berlin, Berlin, Germany.
[Ti] Título:German translation, cultural adaptation, and validation of the Health Literacy Questionnaire (HLQ).
[So] Source:PLoS One;12(2):e0172340, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The Health Literacy Questionnaire (HLQ), developed in Australia in 2012 using a 'validity-driven' approach, has been rapidly adopted and is being applied in many countries and languages. It is a multidimensional measure comprising nine distinct domains that may be used for surveys, needs assessment, evaluation and outcomes assessment as well as for informing service improvement and the development of interventions. The aim of this paper is to describe the German translation of the HLQ and to present the results of the validation of the culturally adapted version. The HLQ comprises 44 items, which were translated and culturally adapted to the German context. This study uses data collected from a sample of 1,058 persons with chronic conditions. Statistical analyses include descriptive and confirmatory factor analyses. In one-factor congeneric models, all scales demonstrated good fit after few model adjustments. In a single, highly restrictive nine-factor model (no cross-loadings, no correlated errors) replication of the original English-language version was achieved with fit indices and psychometric properties similar to the original HLQ. Reliability for all scales was excellent, with a Cronbach's Alpha of at least 0.77. High to very high correlations between some HLQ factors were observed, suggesting that higher order factors may be present. Our rigorous development and validation protocol, as well as strict adaptation processes, have generated a remarkable reproduction of the HLQ in German. The results of this validation provide evidence that the HLQ is robust and can be recommended for use in German-speaking populations. TRIAL REGISTRATION: German Clinical Trial Registration (DRKS): DRKS00000584. Registered 23 March 2011.
[Mh] Termos MeSH primário: Doença Crônica/epidemiologia
Alfabetização em Saúde
Linguagem
Psicometria/métodos
[Mh] Termos MeSH secundário: Adulto
Idoso
Idoso de 80 Anos ou mais
Austrália/epidemiologia
Cultura
Feminino
Alemanha
Educação em Saúde
Administração de Serviços de Saúde
Seres Humanos
Masculino
Meia-Idade
Inquéritos e Questionários
Traduções
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170225
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0172340


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[PMID]:28212638
[Au] Autor:Gadsby EW; Peckham S; Coleman A; Bramwell D; Perkins N; Jenkins LM
[Ad] Endereço:Centre for Health Services Studies, University of Kent, Canterbury, UK. E.Gadsby@kent.ac.uk.
[Ti] Título:Commissioning for health improvement following the 2012 health and social care reforms in England: what has changed?
[So] Source:BMC Public Health;17(1):211, 2017 Feb 17.
[Is] ISSN:1471-2458
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The wide-ranging program of reforms brought about by the Health and Social Care Act (2012) in England fundamentally changed the operation of the public health system, moving responsibility for the commissioning and delivery of services from the National Health Service to locally elected councils and a new national public health agency. This paper explores the ways in which the reforms have altered public health commissioning. METHODS: We conducted multi-methods research over 33 months, incorporating national surveys of Directors of Public Health and local council elected members at two time-points, and in-depth case studies in five purposively selected geographical areas. RESULTS: Public health commissioning responsibilities have changed and become more fragmented, being split amongst a range of different organisations, most of which were newly created in 2013. There is much change in the way public health commissioning is done, in who is doing it, and in what is commissioned, since the reforms. There is wider consultation on decisions in the local council setting than in the NHS, and elected members now have a strong influence on public health prioritisation. There is more (and different) scrutiny being applied to public health contracts, and most councils have embarked on wide-ranging changes to the health improvement services they commission. Public health money is being used in different ways as councils are adapting to increasing financial constraint. CONCLUSIONS: Our findings suggest that, while some of the intended opportunities to improve population health and create a more joined-up system with clearer leadership have been achieved, fragmentation, dispersed decision-making and uncertainties regarding funding remain significant challenges. There have been profound changes in commissioning processes, with consequences for what health improvement services are ultimately commissioned. Time (and further research) will tell if any of these changes lead to improved population health outcomes and reduced health inequalities, but many of the opportunities brought about by the reforms are threatened by the continued flux in the system.
[Mh] Termos MeSH primário: Reforma dos Serviços de Saúde/organização & administração
Administração de Serviços de Saúde
Medicina Estatal/organização & administração
[Mh] Termos MeSH secundário: Contratos
Inglaterra
Seres Humanos
Liderança
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170911
[Lr] Data última revisão:
170911
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170219
[St] Status:MEDLINE
[do] DOI:10.1186/s12889-017-4122-1


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[PMID]:28192425
[Au] Autor:Sartor P; Colaianni I; Cardinal MV; Bua J; Freilij H; Gürtler RE
[Ad] Endereço:Universidad de Buenos Aires, Consejo Nacional de Investigaciones Científicas y Técnicas, Instituto de Ecología, Genética y Evolución de Buenos Aires (IEGEBA), Facultad de Ciencias Exactas y Naturales, Buenos Aires, Argentina.
[Ti] Título:Improving access to Chagas disease diagnosis and etiologic treatment in remote rural communities of the Argentine Chaco through strengthened primary health care and broad social participation.
[So] Source:PLoS Negl Trop Dis;11(2):e0005336, 2017 Feb.
[Is] ISSN:1935-2735
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Rural populations in the Gran Chaco region have large prevalence rates of Trypanosoma cruzi infection and very limited access to diagnosis and treatment. We implemented an innovative strategy to bridge these gaps in 13 rural villages of Pampa del Indio held under sustained vector surveillance and control. METHODOLOGY: The non-randomized treatment program included participatory workshops, capacity strengthening of local health personnel, serodiagnosis, qualitative and quantitative PCRs, a 60-day treatment course with benznidazole and follow-up. Parents and healthcare agents were instructed on drug administration and early detection and notification of adverse drug-related reactions (ADR). Healthcare agents monitored medication adherence and ADRs at village level. PRINCIPAL FINDINGS: The seroprevalence of T. cruzi infection was 24.1% among 395 residents up to 18 years of age examined. Serodiagnostic (70%) and treatment coverage (82%) largely exceeded local historical levels. Sixty-six (85%) of 78 eligible patients completed treatment with 97% medication adherence. ADRs occurred in 32% of patients, but most were mild and manageable. Four patients showing severe or moderate ADRs required treatment withdrawal. T. cruzi DNA was detected by qPCR in 47 (76%) patients before treatment, and persistently occurred in only one patient over 20-180 days posttreatment. CONCLUSIONS AND SIGNIFICANCE: Our results demonstrate that diagnosis and treatment of T. cruzi infection in remote, impoverished rural areas can be effectively addressed through strengthened primary healthcare attention and broad social participation with adequate external support. This strategy secured high treatment coverage and adherence; effectively managed ADRs, and provided early evidence of positive therapeutic responses.
[Mh] Termos MeSH primário: Doença de Chagas/diagnóstico
Doença de Chagas/tratamento farmacológico
Acesso aos Serviços de Saúde
Administração de Serviços de Saúde
Tripanossomicidas/administração & dosagem
[Mh] Termos MeSH secundário: Argentina
Seres Humanos
Atenção Primária à Saúde
População Rural
Participação Social
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Trypanocidal Agents)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170619
[Lr] Data última revisão:
170619
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170214
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pntd.0005336


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[PMID]:28148251
[Au] Autor:Henriksson DK; Ayebare F; Waiswa P; Peterson SS; Tumushabe EK; Fredriksson M
[Ad] Endereço:Karolinska Institutet, Stockholm, Sweden. Dorcus.Kiwanuka@ki.se.
[Ti] Título:Enablers and barriers to evidence based planning in the district health system in Uganda; perceptions of district health managers.
[So] Source:BMC Health Serv Res;17(1):103, 2017 Feb 02.
[Is] ISSN:1472-6963
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The District Health System was endorsed as the key strategy to achieve 'Health for all' during the WHO organized inter-regional meeting in Harare in 1987. Many expectations were put upon the district health system, including planning. Although planning should be evidence based to prioritize activities, in Uganda it has been described as occurring more by chance than by choice. The role of planning is entrusted to the district health managers with support from the Ministry of Health and other stakeholders, but there is limited knowledge on the district health manager's capacity to carry out evidence-based planning. The aim of this study was to determine the barriers and enablers to evidence-based planning at the district level. METHODS: This qualitative study collected data through key informant interviews with district managers from two purposefully selected districts in Uganda that have been implementing evidence-based planning. A deductive process of thematic analysis was used to classify responses within themes. RESULTS: There were considerable differences between the districts in regard to the barriers and enablers for evidence-based planning. Variations could be attributed to specific contextual and environmental differences such as human resource levels, date of establishment of the district, funding and the sociopolitical environment. The perceived lack of local decision space coupled with the perception that the politicians had all the power while having limited knowledge on evidence-based planning was considered an important barrier. CONCLUSION: There is a need to review the mandate of the district managers to make decisions in the planning process and the range of decision space available within the district health system. Given the important role elected officials play in a decentralized system a concerted effort should be made to increase their knowledge on evidence-based planning and the district health system as a whole.
[Mh] Termos MeSH primário: Planejamento em Saúde/organização & administração
Administração de Serviços de Saúde
Política
[Mh] Termos MeSH secundário: Pessoal Administrativo/psicologia
Atitude do Pessoal de Saúde
Tomada de Decisões
Prática Clínica Baseada em Evidências
Programas Governamentais
Seres Humanos
Percepção
Uganda
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170731
[Lr] Data última revisão:
170731
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170203
[St] Status:MEDLINE
[do] DOI:10.1186/s12913-017-2059-9


  10 / 4242 MEDLINE  
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[PMID]:28130686
[Au] Autor:Perner A; Rhodes A; Venkatesh B; Angus DC; Martin-Loeches I; Preiser JC; Vincent JL; Marshall J; Reinhart K; Joannidis M; Opal SM
[Ad] Endereço:Department of Intensive Care, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark. anders.perner@regionh.dk.
[Ti] Título:Sepsis: frontiers in supportive care, organisation and research.
[So] Source:Intensive Care Med;43(4):496-508, 2017 Apr.
[Is] ISSN:1432-1238
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Because of its high incidence and clinical complexity, sepsis is a major challenge to clinicians and researchers and a global burden to healthcare systems and society. Despite recent progress, short- and long-term morbidity, mortality and costs remain high in both developed and developing countries. Thus, further improvements in supportive interventions and organisation of care are likely to have a substantial impact upon global health. In this narrative review, invited experts describe the challenges and progress to be made in sepsis research and care in the near future. We focus on supportive care (pulmonary, endocrine, renal, and nutritional support, mediator modulation and precision medicine), organisational themes (guidelines, outcome measures and stakeholder involvement) and clinical research as key areas to improving the care and outcomes of patients with sepsis.
[Mh] Termos MeSH primário: Pesquisa Biomédica/organização & administração
Efeitos Psicossociais da Doença
Avaliação de Processos e Resultados (Cuidados de Saúde)
Sepse/terapia
[Mh] Termos MeSH secundário: Carga Global da Doença
Guias como Assunto
Administração de Serviços de Saúde
Seres Humanos
Incidência
Medicina de Precisão
Sepse/mortalidade
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170919
[Lr] Data última revisão:
170919
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170129
[St] Status:MEDLINE
[do] DOI:10.1007/s00134-017-4677-4



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