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[PMID]:29375217
[Au] Autor:Siavoshi F; Saniee P
[Ad] Endereço:Department of Microbiology, School of Biology, University College of Sciences, University of Tehran, Tehran 14176-14411, Iran. siavoshi@khayam.ut.ac.ir.
[Ti] Título: accommodates non-culturable its vacuole - Koch's postulates aren't applicable.
[So] Source:World J Gastroenterol;24(2):310-314, 2018 Jan 14.
[Is] ISSN:2219-2840
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The following are the responses to the "letter to the editor" (" is preserved in yeast vacuoles! Does Koch's postulates confirm it?") authored by Nader Alipour and Nasrin Gaeini that rejected the methods, results, discussions and conclusions summarized in the review article authored by Siavoshi F and Saniee P. In the article, 7 papers, published between 1998 and 2013, were reviewed. The 7 papers had been reviewed and judged very carefully by the assigned expertise of the journals involved, including the reviewers of the ( ), before publication. In the review article, 121 references were used to verify the methods, results and discussions of these 7 papers. The review article was edited by the trustworthy British editor of the ( ), and the final version was rechecked and finally accepted by the reviewers of ( ). None of the reviewers made comments like those in this "letter to the editor", especially the humorous comments, which seem unprofessional and nonscientific. Above all, the authors' comments show a lack of understanding of basic and advanced microbiology, e.g. bacterial endosymbiosis in eukaryotic cells. Accordingly, their comments all through the letter contain misconceptions. The comments are mostly based on personal conclusions, without any scientific support. It would have been beneficial if the letter had been reviewed by the reviewers of the article by Siavoshi and Saniee.
[Mh] Termos MeSH primário: Helicobacter pylori
Vacúolos/microbiologia
[Mh] Termos MeSH secundário: Candida
Gastroenterologia
Helicobacter
[Pt] Tipo de publicação:JOURNAL ARTICLE; COMMENT
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180131
[Lr] Data última revisão:
180131
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180130
[St] Status:MEDLINE
[do] DOI:10.3748/wjg.v24.i2.310


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[PMID]:29193347
[Ti] Título:In Memoriam Ben Vainer 18.6.1969-21.6.2017.
[So] Source:APMIS;125(12):1041, 2017 12.
[Is] ISSN:1600-0463
[Cp] País de publicação:Denmark
[La] Idioma:eng
[Mh] Termos MeSH primário: Gastroenterologia/história
Patologia/história
[Mh] Termos MeSH secundário: Dinamarca
História do Século XX
História do Século XXI
Seres Humanos
[Pt] Tipo de publicação:BIOGRAPHY; HISTORICAL ARTICLE; JOURNAL ARTICLE
[Ps] Nome de pessoa como assunto:Vainer B
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180130
[Lr] Data última revisão:
180130
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171202
[St] Status:MEDLINE
[do] DOI:10.1111/apm.12776


  3 / 7455 MEDLINE  
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[PMID]:29184183
[Au] Autor:Boesmans W; Hao MM; Vanden Berghe P
[Ad] Endereço:Laboratory for Enteric Neuroscience (LENS), Translational Research Center for Gastrointestinal Disorders (TARGID), University of Leuven, Herestraat 49, O&N 1 Box 701, 3000 Leuven, Belgium.
[Ti] Título:Optogenetic and chemogenetic techniques for neurogastroenterology.
[So] Source:Nat Rev Gastroenterol Hepatol;15(1):21-38, 2018 Jan.
[Is] ISSN:1759-5053
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Optogenetics and chemogenetics comprise a wide variety of applications in which genetically encoded actuators and indicators are used to modulate and monitor activity with high cellular specificity. Over the past 10 years, development of these genetically encoded tools has contributed tremendously to our understanding of integrated physiology. In concert with the continued refinement of probes, strategies to target transgene expression to specific cell types have also made much progress in the past 20 years. In addition, the successful implementation of optogenetic and chemogenetic techniques thrives thanks to ongoing advances in live imaging microscopy and optical technology. Although innovation of optogenetic and chemogenetic methods has been primarily driven by researchers studying the central nervous system, these techniques also hold great promise to boost research in neurogastroenterology. In this Review, we describe the different classes of tools that are currently available and give an overview of the strategies to target them to specific cell types in the gut wall. We discuss the possibilities and limitations of optogenetic and chemogenetic technology in the gut and provide an overview of their current use, with a focus on the enteric nervous system. Furthermore, we suggest some experiments that can advance our understanding of how the intrinsic and extrinsic neural networks of the gut control gastrointestinal function.
[Mh] Termos MeSH primário: Gastroenterologia
Neurologia
Optogenética
[Mh] Termos MeSH secundário: Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180102
[Lr] Data última revisão:
180102
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171130
[St] Status:MEDLINE
[do] DOI:10.1038/nrgastro.2017.151


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[PMID]:29173724
[Au] Autor:Shulman BB
[Ad] Endereço:Office of the Dean, School of Health and Medical Sciences, Seton Hall University, 400 South Orange Avenue, NJ 07079, USA. Electronic address: brian.shulman@shu.edu.
[Ti] Título:Pediatric Speech and Language Perspectives on Interprofessional Practice.
[So] Source:Pediatr Clin North Am;65(1):xvii-xix, 2018 02.
[Is] ISSN:1557-8240
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Audiologia
Relações Interprofissionais
Transtornos da Linguagem
Pediatria
Patologia da Fala e Linguagem
[Mh] Termos MeSH secundário: Adolescente
Criança
Pré-Escolar
Gastroenterologia
Seres Humanos
Lactente
Transtornos da Linguagem/diagnóstico
Transtornos da Linguagem/etiologia
Transtornos da Linguagem/terapia
Terapia da Linguagem
Fonoterapia
[Pt] Tipo de publicação:INTRODUCTORY JOURNAL ARTICLE
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171219
[Lr] Data última revisão:
171219
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171128
[St] Status:MEDLINE


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[PMID]:29173303
[Au] Autor:Beinvogl B; Sabharwal S; McSweeney M; Nurko S
[Ad] Endereço:Center for Motility and Functional Gastrointestinal Disorders, Boston Children's Hospital, Boston, MA; Division of Pediatric Gastroenterology, Boston Children's Hospital, Boston, MA.
[Ti] Título:Are We Using Abdominal Radiographs Appropriately in the Management of Pediatric Constipation?
[So] Source:J Pediatr;191:179-183, 2017 Dec.
[Is] ISSN:1097-6833
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To identify the reasons why pediatric gastroenterologists obtain abdominal radiographs in the management of pediatric constipation. STUDY DESIGN: This was a prospective study surveying providers regarding their rationale, interpretation, resultant change, and confidence in their management before and after obtaining KUBs in patients seen for suspected constipation. Demographics and clinical findings were obtained from medical records. RESULTS: A total of 24 providers were surveyed after 72 patient encounters. Reasons for obtaining an abdominal radiograph included evaluation of stool burden (70%), need for a clean out (35%), fecal impaction (27%), cause of abdominal pain (24%), demonstration of stool burden to families (14%), assessment of response to therapy (13%), or encopresis (10%). The plan was changed in 47.6% of cases based on radiographic findings. In cases in which a plan was outlined before obtaining the radiograph (69%), the initial plan was implemented on average in 52.5%. In cases with no plans before obtaining the radiograph, previously unconsidered plans were implemented in 8.7%. Provider confidence in the management plan increased from 2.4 ± 2.7 to 4.1 ± 1.8 (P < .05) after the abdominal radiograph. CONCLUSION: Abdominal radiographs commonly are obtained by pediatric gastroenterologists in the evaluation and management of constipation. The majority used it to make a diagnosis, and nearly one-half changed their management based on the imaging findings. Overall, they reported an improved confidence in their management plan, despite evidence that radiographic findings poorly correlate with clinical severity. This study highlights the need for further provider education regarding the recommendations delineated in existing constipation guidelines.
[Mh] Termos MeSH primário: Tomada de Decisão Clínica/métodos
Constipação Intestinal/diagnóstico por imagem
Gastroenterologia
Fidelidade a Diretrizes/estatística & dados numéricos
Pediatria
Padrões de Prática Médica/estatística & dados numéricos
[Mh] Termos MeSH secundário: Dor Abdominal/diagnóstico por imagem
Dor Abdominal/etiologia
Adolescente
Boston
Criança
Pré-Escolar
Competência Clínica
Constipação Intestinal/etiologia
Constipação Intestinal/terapia
Feminino
Pesquisas sobre Serviços de Saúde
Seres Humanos
Masculino
Guias de Prática Clínica como Assunto
Estudos Prospectivos
Radiografia Abdominal
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171211
[Lr] Data última revisão:
171211
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171128
[St] Status:MEDLINE


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[PMID]:28913613
[Au] Autor:Hossain N; Puchakayala B; Kanwar P; Verma S; Abraham G; Ivanov Z; Niaz MO; Mohanty SR
[Ad] Endereço:Department of Gastroenterology and Hepatobiliary Disease, New York Presbyterian Brooklyn Methodist Hospital, 506, 6th Street, Brooklyn, NY, 11215, USA.
[Ti] Título:Risk Factor Analysis Between Newly Screened and Established Hepatitis C in GI and Hepatology Clinics.
[So] Source:Dig Dis Sci;62(11):3193-3199, 2017 Nov.
[Is] ISSN:1573-2568
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Several studies show inconsistencies in the rate of hepatitis C virus (HCV) detection among baby boomers (born 1945-1965). We conducted a cross-sectional HCV screening followed by a case-controlled comparison of the newly screened population with established HCV subjects. METHOD: Enrollment was offered to subjects aged 40-75 at our gastroenterology and hepatology clinics. Demographic data and potential risk factors were obtained, and HCV antibody test was offered to those who had never been screened and compared with a group with established HCV. Logistic regression analysis and Fisher's exact test were performed. RESULTS: Six hundred and seventy-five patients were offered participation, of whom 128 declined while 50 consented to participate but did not perform the HCV antibody test. Of 497 enrolled subjects, 252 patients had HCV, while 245 subjects (188 patients among "baby boomer") underwent screening for HCV. There were more females (62.4 vs. 41.7%) and immigrants (34.7 vs. 22.2%) among the newly screened group. Among the screened population, five patients had HCV antibody (2.04%), and two of them had positive viral load (0.82%) of whom only one fell in the baby boomer category (0.53%). Compared to HCV group, screened group had significantly lower-risk factors, such as IV drug use (1.22 vs. 43.3%), intranasal cocaine use (14.3 vs. 49.6%), and blood transfusion (18.8 vs. 32.5%). CONCLUSION: We found a slightly lower but similar prevalence of HCV antibody when screening based on birth cohort as compared to larger baby boomer studies. Future studies evaluating addition of other screening strategies or possibly universal screening may be needed.
[Mh] Termos MeSH primário: Gastroenterologia
Hepacivirus/imunologia
Anticorpos Anti-Hepatite C/sangue
Hepatite C/diagnóstico
Ambulatório Hospitalar
[Mh] Termos MeSH secundário: Adulto
Fatores Etários
Idoso
Biomarcadores/sangue
Estudos Transversais
Feminino
Hepatite C/sangue
Hepatite C/epidemiologia
Hepatite C/virologia
Seres Humanos
Masculino
Programas de Rastreamento/métodos
Meia-Idade
Cidade de Nova Iorque/epidemiologia
Valor Preditivo dos Testes
Fatores de Risco
Estudos Soroepidemiológicos
Testes Sorológicos
Carga Viral
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Biomarkers); 0 (Hepatitis C Antibodies)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171106
[Lr] Data última revisão:
171106
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170916
[St] Status:MEDLINE
[do] DOI:10.1007/s10620-017-4754-0


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[PMID]:28815353
[Au] Autor:Kumar NL; Perencevich ML; Trier JS
[Ad] Endereço:Division of Gastroenterology, Hepatology and Endoscopy, Brigham and Women's Hospital, 75 Francis Street, Boston, MA, 02115, USA. nlkumar@partners.org.
[Ti] Título:Perceptions of the Inpatient Training Experience: A Nationwide Survey of Gastroenterology Program Directors and Fellows.
[So] Source:Dig Dis Sci;62(10):2631-2647, 2017 Oct.
[Is] ISSN:1573-2568
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Inpatient training is a key component of gastroenterology (GI) fellowship programs nationwide, yet little is known about perceptions of the inpatient training experience. AIM: To compare the content, objectives and quality of the inpatient training experience as perceived by program directors (PD) and fellows in US ACGME-accredited GI fellowship programs. METHODS: We conducted a nationwide, online-based survey of GI PDs and fellows at the conclusion of the 2016 academic year. We queried participants about (1) the current models of inpatient training, (2) the content, objectives, and quality of the inpatient training experience, and (3) the frequency and quality of educational activities on the inpatient service. We analyzed five-point Likert items and rank assessments as continuous variables by an independent t test and compared proportions using the Chi-square test. RESULTS: Survey response rate was 48.4% (75/155) for PDs and a total of 194 fellows completed the survey, with both groups reporting the general GI consult team (>90%) as the primary model of inpatient training. PDs and fellows agreed on the ranking of all queried responsibilities of the inpatient fellow to develop during the inpatient service. However, fellows indicated that attendings spent less time teaching and provided less formal feedback than that perceived by PDs (p < 0.0001). PDs rated the overall quality of the inpatient training experience (p < 0.0001) and education on the wards (p = 0.0003) as better than overall ratings by fellows. CONCLUSION: Although GI fellows and PDs agree on the importance of specific fellow responsibilities on the inpatient service, fellows report experiencing less teaching and feedback from attendings than that perceived by PDs. Committing more time to education and assessment may improve fellows' perceptions of the inpatient training experience.
[Mh] Termos MeSH primário: Atitude do Pessoal de Saúde
Educação de Pós-Graduação em Medicina/métodos
Docentes de Medicina/psicologia
Gastroenterologistas/educação
Gastroenterologistas/psicologia
Gastroenterologia/educação
Conhecimentos, Atitudes e Prática em Saúde
Pacientes Internados
Internato e Residência
Percepção
[Mh] Termos MeSH secundário: Distribuição de Qui-Quadrado
Competência Clínica
Bolsas de Estudo
Feminino
Feedback Formativo
Seres Humanos
Masculino
Avaliação de Programas e Projetos de Saúde
Inquéritos e Questionários
Carga de Trabalho
[Pt] Tipo de publicação:EDITORIAL
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171024
[Lr] Data última revisão:
171024
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170818
[St] Status:MEDLINE
[do] DOI:10.1007/s10620-017-4711-y


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[PMID]:28777045
[Au] Autor:Cerny A
[Ad] Endereço:1 Epatocentro Ticino, Lugano.
[Ti] Título:Hepatitis..
[So] Source:Ther Umsch;74(3):77, 2017 Jul.
[Is] ISSN:0040-5930
[Cp] País de publicação:Switzerland
[La] Idioma:ger
[Mh] Termos MeSH primário: Gastroenterologia/tendências
Hepatite/diagnóstico
Hepatite/terapia
[Mh] Termos MeSH secundário: Hepatite/virologia
Seres Humanos
[Pt] Tipo de publicação:INTRODUCTORY JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171005
[Lr] Data última revisão:
171005
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170805
[St] Status:MEDLINE
[do] DOI:10.1024/0040-5930/a000888


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[PMID]:28753260
[Au] Autor:Food and Drug Administration, HHS
[Ti] Título:Medical Devices; Gastroenterology-Urology Devices; Classification of the Oral Removable Palatal Space Occupying Device for Weight Management and/or Weight Loss. Final order.
[So] Source:Fed Regist;82(144):35067-9, 2017 Jul 28.
[Is] ISSN:0097-6326
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The Food and Drug Administration (FDA or Agency) is classifying the oral removable palatal space occupying device for weight management and/or weight loss into class II (special controls). The special controls that will apply to the device are identified in this order and will be part of the codified language for the oral removable palatal space occupying device for weight management and/or weight loss classification. The Agency is classifying the device into class II (special controls) in order to provide a reasonable assurance of safety and effectiveness of the device.
[Mh] Termos MeSH primário: Segurança de Equipamentos/classificação
Gastroenterologia/classificação
Gastroenterologia/instrumentação
[Mh] Termos MeSH secundário: Seres Humanos
Palato
Perda de Peso
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170804
[Lr] Data última revisão:
170804
[Sb] Subgrupo de revista:T
[Da] Data de entrada para processamento:170729
[St] Status:MEDLINE


  10 / 7455 MEDLINE  
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[PMID]:28724036
[Au] Autor:Passos TR; Santos FS; Martins MC; Pinto VB; Carrilho FJ; Ono SK
[Ad] Endereço:Resident Pharmacist at Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo, SP, Brazil.
[Ti] Título:Clinical pharmacology profile of care in Hepatology clinic.
[So] Source:Rev Assoc Med Bras (1992);63(5):401-406, 2017 May.
[Is] ISSN:1806-9282
[Cp] País de publicação:Brazil
[La] Idioma:eng
[Ab] Resumo:Since 2010, the Clinical Gastroenterology and Hepatology Division of the Central Institute of Hospital das Clínicas of the University of São Paulo Medical School (HC-FMUSP, in the Portuguese acronym) has been developing specialized electives assistance activities in the Outpatient Specialty Clinic, Secondary Level, in São Paulo NGA-63 Várzea do Carmo. The objective of this study was to analyze the pharmacotherapeutic profile of patients. This is a cross-sectional and retrospective study in which patients were seen at the Hepatology sector and the results were submitted to descriptive statistics. During the study period, 492 patients were treated at the clinic, with a mean age of 58.9 years and frequency of 61.2% female and 74.8% living in São Paulo. This population was served by various other medical specialties (cardiology and endocrine among others) and the major liver diagnoses were: chronic hepatitis B and C and fatty liver. Comorbidities were also identified, such as diabetes, hypertension and dyslipidemia. Most patients took their medication in the Basic Health Units. We found that 30% of patients use of more than five medications and the most prescribed were omeprazole 208 (42.3%), metformin 132 (26.8%) and losartan 80 (16.3%). Because it is an adult/elderly population, with several comorbidities and polymedication, it is important to be aware of the rational use of medication. The multidisciplinary team is important in applying correct conducts for the safe use of medicines, to reduce the burden on health spending and improving the quality of life of patients.
[Mh] Termos MeSH primário: Revisão de Uso de Medicamentos/estatística & dados numéricos
Gastroenterologia/estatística & dados numéricos
Hepatopatias/epidemiologia
Ambulatório Hospitalar/estatística & dados numéricos
[Mh] Termos MeSH secundário: Idoso
Brasil/epidemiologia
Comorbidade
Estudos Transversais
Feminino
Seres Humanos
Masculino
Meia-Idade
Polimedicação
Valores de Referência
Estudos Retrospectivos
Distribuição por Sexo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170929
[Lr] Data última revisão:
170929
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170721
[St] Status:MEDLINE



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