Base de dados : MEDLINE
Pesquisa : H02.403.763 [Categoria DeCS]
Referências encontradas : 2898 [refinar]
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[PMID]:28470451
[Au] Autor:Collins SC
[Ad] Endereço:Division of Reproductive Endocrinology and Infertility, Yale School of Medicine, 150 Sargent Drive, Second Floor, New Haven, CT, 06511, USA. Stephen.c.collins@yale.edu.
[Ti] Título:Precision reproductive medicine: multigene panel testing for infertility risk assessment.
[So] Source:J Assist Reprod Genet;34(8):967-973, 2017 Aug.
[Is] ISSN:1573-7330
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:The concept of precision medicine relies on a thorough understanding of the consequences of unique features of individual patients, such as environmental exposures and genetic profiles. A key component of implementing individualized care in this paradigm will be improved assessment of genetic risk. Compared with single gene tests, multigene panel testing-which has recently become commercially available for female infertility-offers the possibility of a more comprehensive and efficient risk evaluation. However, as the use of multigene panel testing for breast cancer risk has shown, this approach must be used judiciously to ensure its usefulness in a clinical setting. Key challenges which have been encountered in oncology include the interpretation of gene variants of questionable clinical effect and a lack of evidence to guide management after variants are identified. In this review, the core concepts of multigene panel testing for risk assessment are discussed, with careful attention to both its shortcomings as well as its potential for benefit in reproductive medicine.
[Mh] Termos MeSH primário: Infertilidade/genética
[Mh] Termos MeSH secundário: Testes Genéticos/métodos
Seres Humanos
Medicina Reprodutiva/métodos
Medição de Risco/métodos
Fatores de Risco
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180202
[Lr] Data última revisão:
180202
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170505
[St] Status:MEDLINE
[do] DOI:10.1007/s10815-017-0938-y


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[PMID]:29284224
[Au] Autor:Skrzypek M; Wdowiak A; Marzec A
[Ad] Endereço:Department of Clinical Dietetics, Faculty of Health Sciences, Medical University, Lublin, Poland. michal.skrzypek@umlub.pl.
[Ti] Título:Application of dietetics in reproductive medicine.
[So] Source:Ann Agric Environ Med;24(4):559-565, 2017 Dec 23.
[Is] ISSN:1898-2263
[Cp] País de publicação:Poland
[La] Idioma:eng
[Ab] Resumo:In the light of up-to-date epidemiological data concerning the prevalence of infertility, and also considering the scale of the problem of obesity and proven cause-effect relationship between abnormal body weight and infertility, it is justifiable to undertake the task of systematization of the state of knowledge concerning nutritional correlates of infertility, in order to create a scientific basis for the formulation of the assumptions of a fertility diet. The study is an attempt to systematize the current state of knowledge concerning the importance of energy and structural (qualitative) aspects of nutrition in the prevention and treatment of infertility.
[Mh] Termos MeSH primário: Dietética/métodos
Infertilidade/dietoterapia
Medicina Reprodutiva/métodos
[Mh] Termos MeSH secundário: Animais
Dietética/tendências
Seres Humanos
Infertilidade/metabolismo
Estado Nutricional
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180105
[Lr] Data última revisão:
180105
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171230
[St] Status:MEDLINE


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[PMID]:29202968
[Au] Autor:Ethics Committee of the American Society for Reproductive Medicine. Electronic address: ASRM@asrm.org; Ethics Committee of the American Society for Reproductive Medicine
[Ti] Título:Child-rearing ability and the provision of fertility services: an Ethics Committee opinion.
[So] Source:Fertil Steril;108(6):944-947, 2017 Dec.
[Is] ISSN:1556-5653
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Fertility programs may withhold services from prospective patients on the basis of well-grounded reasons that those patients will be unable to provide minimally adequate or safe care for offspring. This document was reviewed and updated; this version replaces the previous version of this document, last published July 2013 (Fertil Steril 2013;100:50-53).
[Mh] Termos MeSH primário: Educação Infantil
Bem-Estar da Criança
Comissão de Ética/normas
Infertilidade/terapia
Poder Familiar
Pais
Recusa do Médico a Tratar
Medicina Reprodutiva/normas
Técnicas de Reprodução Assistida/normas
[Mh] Termos MeSH secundário: Criança
Educação Infantil/psicologia
Bem-Estar da Criança/psicologia
Fertilidade
Seres Humanos
Infertilidade/diagnóstico
Infertilidade/fisiopatologia
Infertilidade/psicologia
Poder Familiar/psicologia
Pais/psicologia
Direitos do Paciente/normas
Recusa do Médico a Tratar/ética
Medicina Reprodutiva/ética
Técnicas de Reprodução Assistida/ética
Medição de Risco
Fatores de Risco
[Pt] Tipo de publicação:JOURNAL ARTICLE; PRACTICE GUIDELINE
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171215
[Lr] Data última revisão:
171215
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171206
[St] Status:MEDLINE


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[PMID]:28865538
[Au] Autor:Practice Committee of the American Society for Reproductive Medicine. Electronic address: ASRM@asrm.org; Practice Committee of the American Society for Reproductive Medicine
[Ti] Título:Removal of myomas in asymptomatic patients to improve fertility and/or reduce miscarriage rate: a guideline.
[So] Source:Fertil Steril;108(3):416-425, 2017 Sep.
[Is] ISSN:1556-5653
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The purpose of this systematic review is to evaluate if uterine myomas impact the likelihood of pregnancy and pregnancy loss, and if myomectomy influences pregnancy outcomes in asymptomatic women. There is insufficient evidence to conclude that the presence of myomas reduces the likelihood of achieving pregnancy. However, there is fair evidence that myomectomy (open or laparoscopic) for cavity-distorting myomas (intramural or intramural with a submucosal component) improves pregnancy rates and reduces the risk of early pregnancy loss. There is fair evidence that hysteroscopic myomectomy for cavity-distorting myomas improves clinical pregnancy rates but insufficient evidence regarding the impact of this procedure on the likelihood of live birth or early pregnancy loss. In women with asymptomatic cavity-distorting myomas, myomectomy may be considered to optimize pregnancy outcomes.
[Mh] Termos MeSH primário: Aborto Espontâneo/prevenção & controle
Preservação da Fertilidade/normas
Infertilidade/prevenção & controle
Leiomioma/cirurgia
Guias de Prática Clínica como Assunto
Medicina Reprodutiva/normas
Neoplasias Uterinas/cirurgia
[Mh] Termos MeSH secundário: Aborto Espontâneo/epidemiologia
Causalidade
Medicina Baseada em Evidências
Feminino
Preservação da Fertilidade/utilização
Seres Humanos
Infertilidade/epidemiologia
Leiomioma/epidemiologia
Gravidez
Resultado da Gravidez/epidemiologia
Prevalência
Resultado do Tratamento
Estados Unidos
Neoplasias Uterinas/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170929
[Lr] Data última revisão:
170929
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170904
[St] Status:MEDLINE


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[PMID]:28760517
[Au] Autor:Zegers-Hochschild F; Adamson GD; Dyer S; Racowsky C; de Mouzon J; Sokol R; Rienzi L; Sunde A; Schmidt L; Cooke ID; Simpson JL; van der Poel S
[Ad] Endereço:University Diego Portales, Program of Ethics and Public Policies in Human Reproduction; Clinica las Condes, Unit of Reproductive Medicine, Santiago, Chile. Electronic address: icmart@icsevents.com.
[Ti] Título:The International Glossary on Infertility and Fertility Care, 2017.
[So] Source:Fertil Steril;108(3):393-406, 2017 Sep.
[Is] ISSN:1556-5653
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:STUDY QUESTION: Can a consensus and evidence-driven set of terms and definitions be generated to be used globally in order to ensure consistency when reporting on infertility issues and fertility care interventions, as well as to harmonize communication among the medical and scientific communities, policy-makers, and lay public including individuals and couples experiencing fertility problems? SUMMARY ANSWER: A set of 283 consensus-based and evidence-driven terminologies used in infertility and fertility care has been generated through an inclusive consensus-based process with multiple stakeholders. WHAT IS KNOWN ALREADY: In 2006 the International Committee for Monitoring Assisted Reproductive Technologies (ICMART) published a first glossary of 53 terms and definitions. In 2009 ICMART together with WHO published a revised version expanded to 87 terms, which defined infertility as a disease of the reproductive system, and increased standardization of fertility treatment terminology. Since 2009, limitations were identified in several areas and enhancements were suggested for the glossary, especially concerning male factor, demography, epidemiology and public health issues. STUDY DESIGN, SIZE, DURATION: Twenty-five professionals, from all parts of the world and representing their expertise in a variety of sub-specialties, were organized into five working groups: clinical definitions; outcome measurements; embryology laboratory; clinical and laboratory andrology; and epidemiology and public health. Assessment for revisions, as well as expansion on topics not covered by the previous glossary, were undertaken. A larger group of independent experts and representatives from collaborating organizations further discussed and assisted in refining all terms and definitions. PARTICIPANTS/MATERIALS, SETTING, METHODS: Members of the working groups and glossary co-ordinators interacted through electronic mail and face-to-face in international/regional conferences. Two formal meetings were held in Geneva, Switzerland, with a final consensus meeting including independent experts as well as observers and representatives of international/regional scientific and patient organizations. MAIN RESULTS AND THE ROLE OF CHANCE: A consensus-based and evidence-driven set of 283 terminologies used in infertility and fertility care was generated to harmonize communication among health professionals and scientists as well as the lay public, patients and policy makers. Definitions such as 'fertility care' and 'fertility awareness' together with terminologies used in embryology and andrology have been introduced in the glossary for the first time. Furthermore, the definition of 'infertility' has been expanded in order to cover a wider spectrum of conditions affecting the capacity of individuals and couples to reproduce. The definition of infertility remains as a disease characterized by the failure to establish a clinical pregnancy; however, it also acknowledges that the failure to become pregnant does not always result from a disease, and therefore introduces the concept of an impairment of function which can lead to a disability. Additionally, subfertility is now redundant, being replaced by the term infertility so as to standardize the definition and avoid confusion. LIMITATIONS, REASONS FOR CAUTION: All stakeholders agreed to the vast majority of terminologies included in this glossary. In cases where disagreements were not resolved, the final decision was reached after a vote, defined before the meeting as consensus if passed with 75%. Over the following months, an external expert group, which included representatives from non-governmental organizations, reviewed and provided final feedback on the glossary. WIDER IMPLICATIONS OF THE FINDINGS: Some terminologies have different definitions, depending on the area of medicine, for example demographic or clinical as well as geographic differences. These differences were taken into account and this glossary represents a multinational effort to harmonize terminologies that should be used worldwide. STUDY FUNDING/COMPETING INTERESTS: None. TRIAL REGISTRATION NUMBER: N/A.
[Mh] Termos MeSH primário: Dicionários como Assunto
Infertilidade/classificação
Infertilidade/terapia
Guias de Prática Clínica como Assunto
Medicina Reprodutiva/normas
Técnicas de Reprodução Assistida/classificação
Terminologia como Assunto
[Mh] Termos MeSH secundário: Seres Humanos
Internacionalidade
Vocabulário Controlado
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170929
[Lr] Data última revisão:
170929
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170802
[St] Status:MEDLINE


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[PMID]:28697914
[Au] Autor:Schlaff WD
[Ad] Endereço:Department of Obstetrics and Gynecology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania. Electronic address: william.schlaff@jefferson.edu.
[Ti] Título:Introduction: The specter of opiate addiction in reproductive medicine.
[So] Source:Fertil Steril;108(2):193-194, 2017 Aug.
[Is] ISSN:1556-5653
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The alarming trend in opiate misuse in developed countries is prompting an increasingly strident public call for action. Although many in our field have assumed that this building crisis does not really affect us or our patients, data show that the emerging demographic at highest risk for misusing opiates clearly includes patients who seek care in our practices. The goals of this Views and Reviews are to provide a clear understanding of emerging trends in opiate misuse, to review the impact of opiates on the reproductive axis, and to suggest practical recommendations aimed at both mitigating iatrogenic influences on promoting misuse and developing treatment frameworks when misuse is suspected or identified. Regrettably, there is little if any information on treatment of opiate misuse in the infertility population; we are perhaps best served by learning from successful approaches used in pregnant patients. It is hoped that this Views and Reviews will stimulate focused research and, ultimately, evidence-based guidelines and pathways that will address this widespread clinical problem.
[Mh] Termos MeSH primário: Infertilidade/diagnóstico
Infertilidade/terapia
Transtornos Relacionados ao Uso de Opioides/diagnóstico
Transtornos Relacionados ao Uso de Opioides/terapia
Complicações na Gravidez/diagnóstico
Complicações na Gravidez/terapia
[Mh] Termos MeSH secundário: Feminino
Fertilidade
Seres Humanos
Masculino
Gravidez
Medicina Reprodutiva/tendências
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170825
[Lr] Data última revisão:
170825
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170713
[St] Status:MEDLINE


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[PMID]:28697912
[Au] Autor:Wright TE
[Ad] Endereço:Department of Obstetrics, Gynecology and Women's Health, and Department of Psychiatry, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii. Electronic address: tewright@hawaii.edu.
[Ti] Título:Screening, brief intervention, and referral to treatment for opioid and other substance use during infertility treatment.
[So] Source:Fertil Steril;108(2):214-221, 2017 Aug.
[Is] ISSN:1556-5653
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Opioid use and misuse have reached epidemic proportions in the United States, especially in women of childbearing age, some of whom seek infertility treatments. Substance use is much more common than many of the conditions routinely screened for during the preconception period, and it can have devastating consequences for the woman and her family. Substance use can worsen infertility, complicate pregnancy, increase medical problems, and lead to psychosocial difficulties for the woman and her family. The reproductive endocrinologist thus has an ethical and medical duty to screen for substance use, provide initial counseling, and refer to specialized treatment as needed. This article provides an overview of screening, brief intervention, and referral to treatment (SBIRT), a public health approach shown to be effective in ameliorating the harms of substance use.
[Mh] Termos MeSH primário: Avaliação Pré-Clínica de Medicamentos/métodos
Infertilidade/terapia
Transtornos Relacionados ao Uso de Opioides/diagnóstico
Transtornos Relacionados ao Uso de Opioides/terapia
Encaminhamento e Consulta/organização & administração
Medicina Reprodutiva/organização & administração
[Mh] Termos MeSH secundário: Avaliação Pré-Clínica de Medicamentos/ética
Seres Humanos
Infertilidade/complicações
Transtornos Relacionados ao Uso de Opioides/complicações
Papel do Médico
Encaminhamento e Consulta/ética
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170825
[Lr] Data última revisão:
170825
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170713
[St] Status:MEDLINE


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[PMID]:28647297
[Au] Autor:Galliano D
[Ad] Endereço:Instituto Valenciano de Infertilidad (IVI), Rome, Italy; and Instituto Valenciano de Infertilidad (IVI), Barcelona, Spain.
[Ti] Título:Use of gonadotropins in infertile patients.
[So] Source:Fertil Steril;108(3):455, 2017 Sep.
[Is] ISSN:1556-5653
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:A new era in the history of gonadotropins.
[Mh] Termos MeSH primário: Gonadotropinas/história
Gonadotropinas/uso terapêutico
Infertilidade Feminina/tratamento farmacológico
Infertilidade Feminina/história
Medicina Reprodutiva/história
[Mh] Termos MeSH secundário: Animais
Feminino
História do Século XX
Seres Humanos
[Pt] Tipo de publicação:EDITORIAL; HISTORICAL ARTICLE
[Nm] Nome de substância:
0 (Gonadotropins)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170929
[Lr] Data última revisão:
170929
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170626
[St] Status:MEDLINE


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[PMID]:28579417
[Au] Autor:Wu HY; Yin O; Monseur B; Selter J; Collins LJ; Lau BD; Christianson MS
[Ad] Endereço:Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, Maryland. Electronic address: hwu36@jhmi.edu.
[Ti] Título:Lesbian, gay, bisexual, transgender content on reproductive endocrinology and infertility clinic websites.
[So] Source:Fertil Steril;108(1):183-191, 2017 Jul.
[Is] ISSN:1556-5653
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To assess geographical distribution and practice characteristics of fertility clinics inclusive of lesbian, gay, bisexual, and transgender (LGBT) patients. DESIGN: Cross-sectional analysis. SETTING: Not applicable. PATIENT(S): None. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Prevalence and geographical distribution of fertility clinic websites with LGBT-specific content, indicated by keywords and home page cues specific to the LGBT patient population. Assessment of relationship between LGBT-specific content and clinic characteristics, including U.S. region, clinic size, private versus academic setting, and state-mandated fertility insurance coverage. RESULT(S): Of 379 websites analyzed, 201 (53%) contained LGBT content. Clinics with the highest proportion of LGBT website content were in the Northeast (59/82, 72%) and West (63/96, 66%), while the lowest proportion was in the Midwest (29/74, 39%) and South (50/127, 39%). Most frequently used terms included lesbian (72%), LGBT/LGBTQ (69%), and gay (68%), while less used terms included trans/transgender (32%) and bisexual (15%). Larger clinic size was associated with LGBT-specific website content (odds ratio, 4.42; 95% confidence interval, 2.07-9.67). Practice type and state-mandated fertility insurance coverage were not associated with a clinic website having LGBT content. CONCLUSION(S): Over half of Society for Assisted Reproductive Technology member fertility clinics included LGBT content on their websites, yet those in the Midwest and South were significantly less likely to do so. Predictive factors for having LGBT website content included location in northeastern and western regions and increasing clinic size. Further studies are needed to evaluate whether inclusion of LGBT content on clinic websites impacts use of reproductive services by the LGBT patient population.
[Mh] Termos MeSH primário: Informação de Saúde ao Consumidor/estatística & dados numéricos
Endocrinologia/educação
Internet/estatística & dados numéricos
Medicina Reprodutiva/educação
Técnicas de Reprodução Assistida/estatística & dados numéricos
Minorias Sexuais e de Gênero/estatística & dados numéricos
[Mh] Termos MeSH secundário: Endocrinologia/estatística & dados numéricos
Feminino
Disparidades em Assistência à Saúde/estatística & dados numéricos
Seres Humanos
Masculino
Medicina Reprodutiva/estatística & dados numéricos
Estados Unidos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170606
[St] Status:MEDLINE


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[PMID]:28579405
[Au] Autor:Pennings G; Segers S; Debrock S; Heindryckx B; Kontozova-Deutsch V; Punjabi U; Vande Velde H; van Steirteghem A; Mertes H
[Ad] Endereço:Bioethics Institute Ghent, Faculty of Arts and Philosophy, Ghent University, Ghent, Belgium. Electronic address: guido.pennings@ugent.be.
[Ti] Título:Human embryo research in Belgium: an overview.
[So] Source:Fertil Steril;108(1):96-107, 2017 Jul.
[Is] ISSN:1556-5653
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To present an overview of the numbers and types of human embryos used in research projects in Belgium from 2007 to 2015. DESIGN: Analysis of all research proposals approved by the Federal Commission for Medical and Scientific Research on Embryos In Vitro. SETTING: Not applicable. PATIENT(S): Not applicable. MAIN OUTCOME MEASURE(S): Number of embryos used for research, number of embryos created for research, and areas of embryo research. RESULT(S): Since 2007, 15,811 embryos were used for 36 research projects. In total, 10,492 (66%) fresh supernumerary embryos (unfit for transfer or freezing) were used, 4,083 (26%) frozen supernumerary embryos (donated by parents whose child wish was completed or abandoned), and 1,236 (8%) embryos created for research. Most projects focused on research into embryo development. Fresh supernumerary embryos were mainly used for human embryonic stem cell (hESC) research. Frozen supernumerary embryos were almost exclusively used for research into embryo development and for hESC research. Embryos created for research were used for research into embryo development, oocyte research, research into cryopreservation of oocytes, and hESC research. CONCLUSION(S): Having concrete data on embryo research is crucial for an informed debate. Moreover, these data are necessary to find out trends in research such as the numbers of embryos needed and the areas of research. Data collection requires a sufficiently clear definition of "research" and "embryo." These conceptual questions frequently reveal lack of clarity in legislation.
[Mh] Termos MeSH primário: Criopreservação/estatística & dados numéricos
Pesquisas com Embriões
Transferência Embrionária/estatística & dados numéricos
Recuperação de Oócitos/estatística & dados numéricos
Medicina Reprodutiva/estatística & dados numéricos
Pesquisa com Células-Tronco
[Mh] Termos MeSH secundário: Bélgica
Seres Humanos
Experimentação Humana Terapêutica
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170818
[Lr] Data última revisão:
170818
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170606
[St] Status:MEDLINE



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