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[PMID]:29045889
[Au] Autor:Paules CI; Marston HD; Eisinger RW; Baltimore D; Fauci AS
[Ad] Endereço:Office of the Director, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
[Ti] Título:The Pathway to a Universal Influenza Vaccine.
[So] Source:Immunity;47(4):599-603, 2017 Oct 17.
[Is] ISSN:1097-4180
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Development of a universal influenza vaccine is a research priority for the National Institute of Allergy and Infectious Diseases (NIAID) at the National Institutes of Health. To facilitate this goal, we convened a workshop in Rockville, Maryland to identify knowledge gaps in influenza research and develop strategies to fill them.
[Mh] Termos MeSH primário: Modelos Animais de Doenças
Vírus da Influenza A/imunologia
Vacinas contra Influenza/imunologia
Influenza Humana/imunologia
[Mh] Termos MeSH secundário: Animais
Furões
Seres Humanos
Vacinas contra Influenza/administração & dosagem
Influenza Humana/prevenção & controle
Influenza Humana/virologia
National Institute of Allergy and Infectious Diseases (U.S.)
Estados Unidos
[Pt] Tipo de publicação:CONGRESSES
[Nm] Nome de substância:
0 (Influenza Vaccines)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171106
[Lr] Data última revisão:
171106
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171019
[St] Status:MEDLINE


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[PMID]:28605260
[Au] Autor:DiCarlo AL; Tamarat R; Rios CI; Benderitter M; Czarniecki CW; Allio TC; Macchiarini F; Maidment BW; Jourdain JR
[Ad] Endereço:a Radiation and Nuclear Countermeasures Program (RNCP), Division of Allergy, Immunology and Transplantation (DAIT), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Rockville, Maryland.
[Ti] Título:Cellular Therapies for Treatment of Radiation Injury: Report from a NIH/NIAID and IRSN Workshop.
[So] Source:Radiat Res;188(2):e54-e75, 2017 Aug.
[Is] ISSN:1938-5404
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:In recent years, there has been increasing concern over the possibility of a radiological or nuclear incident occurring somewhere in the world. Intelligence agencies frequently report that terrorist groups and rogue nations are seeking to obtain radiological or nuclear weapons of mass destruction. In addition, there exists the real possibility that safety of nuclear power reactors could be compromised by natural (such as the tsunami and subsequent Fukushima accident in Japan in March, 2011) or accidental (Three Mile Island, 1979 and Chernobyl, 1986) events. Although progress has been made by governments around the world to prepare for these events, including the stockpiling of radiation countermeasures, there are still challenges concerning care of patients injured during a radiation incident. Because the deleterious and pathological effects of radiation are so broad, it is desirable to identify medical countermeasures that can have a beneficial impact on several tissues and organ systems. Cellular therapies have the potential to impact recovery and tissue/organ regeneration for both early and late complications of radiation exposure. These therapies, which could include stem or blood progenitor cells, mesenchymal stromal cells (MSCs) or cells derived from other tissues (e.g., endothelium or placenta), have shown great promise in treating other nonradiation injuries to and diseases of the bone marrow, skin, gastrointestinal tract, brain, lung and heart. To explore the potential use of these therapies in the treatment of victims after acute radiation exposure, the National Institute of Allergy and Infectious Diseases co-sponsored an international workshop in July, 2015 in Paris, France with the Institut de Radioprotection et de Sûreté Nucléaire. The workshop included discussions of data available from testing in preclinical models of radiation injury to different organs, logistics associated with the practical use of cellular therapies for a mass casualty incident, as well as international regulatory requirements for authorizing such drug products to be legally and readily used in such incidents. This report reviews the data presented, as well as key discussion points from the meeting.
[Mh] Termos MeSH primário: Terapia Baseada em Transplante de Células e Tecidos/métodos
National Institute of Allergy and Infectious Diseases (U.S.)
Lesões por Radiação/terapia
[Mh] Termos MeSH secundário: Animais
França
Regulamentação Governamental
Seres Humanos
National Institute of Allergy and Infectious Diseases (U.S.)/legislação & jurisprudência
Lesões por Radiação/patologia
Estados Unidos
[Pt] Tipo de publicação:CONGRESSES
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170822
[Lr] Data última revisão:
170822
[Sb] Subgrupo de revista:IM; S
[Da] Data de entrada para processamento:170613
[St] Status:MEDLINE
[do] DOI:10.1667/RR14810.1


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[PMID]:28502823
[Au] Autor:Gold DR; Adamkiewicz G; Arshad SH; Celedón JC; Chapman MD; Chew GL; Cook DN; Custovic A; Gehring U; Gern JE; Johnson CC; Kennedy S; Koutrakis P; Leaderer B; Mitchell H; Litonjua AA; Mueller GA; O'Connor GT; Ownby D; Phipatanakul W; Persky V; Perzanowski MS; Ramsey CD; Salo PM; Schwaninger JM; Sordillo JE; Spira A; Suglia SF; Togias A; Zeldin DC; Matsui EC
[Ad] Endereço:Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, Mass; Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Mass. Electronic address: diane.gold@channing.harvard.edu.
[Ti] Título:NIAID, NIEHS, NHLBI, and MCAN Workshop Report: The indoor environment and childhood asthma-implications for home environmental intervention in asthma prevention and management.
[So] Source:J Allergy Clin Immunol;140(4):933-949, 2017 Oct.
[Is] ISSN:1097-6825
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Environmental exposures have been recognized as critical in the initiation and exacerbation of asthma, one of the most common chronic childhood diseases. The National Institute of Allergy and Infectious Diseases; National Institute of Environmental Health Sciences; National Heart, Lung, and Blood Institute; and Merck Childhood Asthma Network sponsored a joint workshop to discuss the current state of science with respect to the indoor environment and its effects on the development and morbidity of childhood asthma. The workshop included US and international experts with backgrounds in allergy/allergens, immunology, asthma, environmental health, environmental exposures and pollutants, epidemiology, public health, and bioinformatics. Workshop participants provided new insights into the biologic properties of indoor exposures, indoor exposure assessment, and exposure reduction techniques. This informed a primary focus of the workshop: to critically review trials and research relevant to the prevention or control of asthma through environmental intervention. The participants identified important limitations and gaps in scientific methodologies and knowledge and proposed and prioritized areas for future research. The group reviewed socioeconomic and structural challenges to changing environmental exposure and offered recommendations for creative study design to overcome these challenges in trials to improve asthma management. The recommendations of this workshop can serve as guidance for future research in the study of the indoor environment and on environmental interventions as they pertain to the prevention and management of asthma and airway allergies.
[Mh] Termos MeSH primário: Poluição do Ar em Ambientes Fechados/efeitos adversos
Asma/prevenção & controle
Indústria Farmacêutica
National Heart, Lung, and Blood Institute (U.S.)
National Institute of Allergy and Infectious Diseases (U.S.)
National Institute of Environmental Health Sciences (U.S.)
Organizações sem Fins Lucrativos
[Mh] Termos MeSH secundário: Animais
Asma/diagnóstico
Asma/epidemiologia
Pesquisa Biomédica
Criança
Consensus Development Conferences, NIH as Topic
Saúde Ambiental
Obtenção de Fundos
Seres Humanos
Estados Unidos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171023
[Lr] Data última revisão:
171023
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170516
[St] Status:MEDLINE


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[PMID]:28483986
[Au] Autor:PrabhuDas MR; Baldwin CL; Bollyky PL; Bowdish DME; Drickamer K; Febbraio M; Herz J; Kobzik L; Krieger M; Loike J; McVicker B; Means TK; Moestrup SK; Post SR; Sawamura T; Silverstein S; Speth RC; Telfer JC; Thiele GM; Wang XY; Wright SD; El Khoury J
[Ad] Endereço:Division of Allergy, Immunology and Transplantation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD 20852; mprabhudas@niaid.nih.gov jelkhoury@mgh.harvard.edu.
[Ti] Título:A Consensus Definitive Classification of Scavenger Receptors and Their Roles in Health and Disease.
[So] Source:J Immunol;198(10):3775-3789, 2017 May 15.
[Is] ISSN:1550-6606
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Scavenger receptors constitute a large family of proteins that are structurally diverse and participate in a wide range of biological functions. These receptors are expressed predominantly by myeloid cells and recognize a diverse variety of ligands including endogenous and modified host-derived molecules and microbial pathogens. There are currently eight classes of scavenger receptors, many of which have multiple names, leading to inconsistencies and confusion in the literature. To address this problem, a workshop was organized by the United States National Institute of Allergy and Infectious Diseases, National Institutes of Health, to help develop a clear definition of scavenger receptors and a standardized nomenclature based on that definition. Fifteen experts in the scavenger receptor field attended the workshop and, after extensive discussion, reached a consensus regarding the definition of scavenger receptors and a proposed scavenger receptor nomenclature. Scavenger receptors were defined as cell surface receptors that typically bind multiple ligands and promote the removal of nonself or altered-self targets. They often function by mechanisms that include endocytosis, phagocytosis, adhesion, and signaling that ultimately lead to the elimination of degraded or harmful substances. Based on this definition, nomenclature and classification of these receptors into 10 classes were proposed. This classification was discussed at three national meetings and input from participants at these meetings was requested. The following manuscript is a consensus statement that combines the recommendations of the initial workshop and incorporates the input received from the participants at the three national meetings.
[Mh] Termos MeSH primário: Receptores Depuradores/classificação
Receptores Depuradores/fisiologia
[Mh] Termos MeSH secundário: Animais
Endocitose
Seres Humanos
Ligantes
Camundongos
National Institute of Allergy and Infectious Diseases (U.S.)/normas
Fagocitose
Receptores Imunológicos/fisiologia
Receptores Depuradores Classe A/fisiologia
Transdução de Sinais
Terminologia como Assunto
Estados Unidos
[Pt] Tipo de publicação:CONSENSUS DEVELOPMENT CONFERENCE, NIH; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Ligands); 0 (Receptors, Immunologic); 0 (Receptors, Scavenger); 0 (Scavenger Receptors, Class A)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:171121
[Lr] Data última revisão:
171121
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170510
[St] Status:MEDLINE
[do] DOI:10.4049/jimmunol.1700373


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[PMID]:28192569
[Au] Autor:Turner PJ; Campbell DE
[Ad] Endereço:Section of Paediatrics, Imperial College London, London, United Kingdom2Discipline of Child and Adolescent Health, University of Sydney, Sydney, Australia.
[Ti] Título:Implementing Primary Prevention for Peanut Allergy at a Population Level.
[So] Source:JAMA;317(11):1111-1112, 2017 03 21.
[Is] ISSN:1538-3598
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Fatores Etários
Hipersensibilidade a Amendoim/prevenção & controle
Guias de Prática Clínica como Assunto
Prevenção Primária/métodos
[Mh] Termos MeSH secundário: Anafilaxia/etiologia
Anafilaxia/mortalidade
Eczema/complicações
Hipersensibilidade Alimentar/diagnóstico
Seres Humanos
Lactente
Análise de Intenção de Tratamento
Uso Excessivo de Produtos e Serviços de Saúde
National Institute of Allergy and Infectious Diseases (U.S.)
Hipersensibilidade a Amendoim/complicações
Hipersensibilidade a Amendoim/diagnóstico
Profilaxia Pré-Exposição/métodos
Ensaios Clínicos Controlados Aleatórios como Assunto
Estados Unidos
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170327
[Lr] Data última revisão:
170327
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170214
[St] Status:MEDLINE
[do] DOI:10.1001/jama.2017.0922


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[PMID]:28137368
[Au] Autor:Togias A; Cooper SF; Acebal ML; Assa'ad A; Baker JR; Beck LA; Block J; Byrd-Bredbenner C; Chan ES; Eichenfield LF; Fleischer DM; Fuchs GJ; Furuta GT; Greenhawt MJ; Gupta RS; Habich M; Jones SM; Keaton K; Muraro A; Plaut M; Rosenwasser LJ; Rotrosen D; Sampson HA; Schneider LC; Sicherer SH; Sidbury R; Spergel J; Stukus DR; Venter C; Boyce JA
[Ad] Endereço:National Institute of Allergy and Infectious Diseases, Bethesda, MD.
[Ti] Título:Addendum Guidelines for the Prevention of Peanut Allergy in the United States: Report of the National Institute of Allergy and Infectious Diseases-Sponsored Expert Panel.
[So] Source:J Pediatr Nurs;32:91-98, 2017 Jan - Feb.
[Is] ISSN:1532-8449
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Food allergy is an important public health problem because it affects children and adults, can be severe and even life-threatening, and may be increasing in prevalence. Beginning in 2008, the National Institute of Allergy and Infectious Diseases, working with other organizations and advocacy groups, led the development of the first clinical guidelines for the diagnosis and management of food allergy. A recent landmark clinical trial and other emerging data suggest that peanut allergy can be prevented through introduction of peanut-containing foods beginning in infancy. OBJECTIVES: Prompted by these findings, along with 25 professional organizations, federal agencies, and patient advocacy groups, the National Institute of Allergy and Infectious Diseases facilitated development of addendum guidelines to specifically address the prevention of peanut allergy. RESULTS: The addendum provides 3 separate guidelines for infants at various risk levels for the development of peanut allergy and is intended for use by a wide variety of health care providers. Topics addressed include the definition of risk categories, appropriate use of testing (specific IgE measurement, skin prick tests, and oral food challenges), and the timing and approaches for introduction of peanut-containing foods in the health care provider's office or at home. The addendum guidelines provide the background, rationale, and strength of evidence for each recommendation. CONCLUSIONS: Guidelines have been developed for early introduction of peanut-containing foods into the diets of infants at various risk levels for peanut allergy.
[Mh] Termos MeSH primário: Arachis/imunologia
Fenômenos Fisiológicos da Nutrição Infantil
Hipersensibilidade a Amendoim/prevenção & controle
Guias de Prática Clínica como Assunto
Prevenção Primária/normas
[Mh] Termos MeSH secundário: Alergia e Imunologia
Criança
Seres Humanos
Tolerância Imunológica
National Institute of Allergy and Infectious Diseases (U.S.)
Medição de Risco/normas
Comportamento de Redução do Risco
Testes Cutâneos
Estados Unidos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170904
[Lr] Data última revisão:
170904
[Sb] Subgrupo de revista:IM; N
[Da] Data de entrada para processamento:170201
[St] Status:MEDLINE


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[PMID]:28120742
[Au] Autor:Greenhawt M
[Ti] Título:The National Institutes of Allergy and Infectious Diseases sponsored guidelines on preventing peanut allergy: A new paradigm in food allergy prevention.
[So] Source:Allergy Asthma Proc;38(2):92-97, 2017 Mar 24.
[Is] ISSN:1539-6304
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Peanut allergy is a significant public health problem without proven treatment or cure at present. In 2000, the American Academy of Pediatrics recommended that solid-food introduction be delayed in infants at high risk, including peanut introduction, until age 3 years. In 2008, the American Academy of Pediatrics revised these recommendations based on limited evidence of benefit and, instead, recommended solid-food introduction not be delayed past 4-6 months of life. In 2015, the Learning Early About Peanut Allergy study showed that early peanut introduction (between 4 and 11 months of life) was associated with a significant absolute and relative risk reduction in the development of peanut allergy compared with delayed introduction. Based on these findings, the National Institutes of Allergy and Infectious Diseases sponsored an expert panel to create an addendum to the 2010 Food Allergy Guidelines that specifically focuses on peanut allergy prevention. The addendum recommends that children with severe eczema, egg allergy, or both have peanut introduced as early as 4-6 months of life, after assessment by a trained allergy specialist. For children with mild-to-moderate eczema, peanut can be introduced at ∼6 months, without the need for specialist evaluation. For children with no eczema, peanut can be introduced in accordance with family and cultural preferences, without the need for specialist evaluation. Adherence to these clinical practice recommendations can help potentially reduce the number of cases of peanut allergy per year. However, this can only be accomplished with the cooperation of parents and health care providers who adhere to these recommendations.
[Mh] Termos MeSH primário: Comportamento Alimentar
Hipersensibilidade a Amendoim/prevenção & controle
Guias de Prática Clínica como Assunto
Comportamento de Redução do Risco
[Mh] Termos MeSH secundário: Fatores Etários
Pré-Escolar
Comorbidade
Dermatite Atópica/epidemiologia
Hipersensibilidade a Ovo/epidemiologia
Seres Humanos
Lactente
National Institute of Allergy and Infectious Diseases (U.S.)
Hipersensibilidade a Amendoim/epidemiologia
Prevenção Primária
Medição de Risco
Prevenção Secundária
Índice de Gravidade de Doença
Estados Unidos
Desmame
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170907
[Lr] Data última revisão:
170907
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170126
[St] Status:MEDLINE
[do] DOI:10.2500/aap.2017.38.4037


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[PMID]:28065802
[Au] Autor:Togias A; Cooper SF; Acebal ML; Assa'ad A; Baker JR; Beck LA; Block J; Byrd-Bredbenner C; Chan ES; Eichenfield LF; Fleischer DM; Fuchs GJ; Furuta GT; Greenhawt MJ; Gupta RS; Habich M; Jones SM; Keaton K; Muraro A; Plaut M; Rosenwasser LJ; Rotrosen D; Sampson HA; Schneider LC; Sicherer SH; Sidbury R; Spergel J; Stukus DR; Venter C; Boyce JA
[Ad] Endereço:National Institute of Allergy and Infectious Diseases, Bethesda, Md.
[Ti] Título:Addendum guidelines for the prevention of peanut allergy in the United States: Report of the National Institute of Allergy and Infectious Diseases-sponsored expert panel.
[So] Source:Ann Allergy Asthma Immunol;118(2):166-173.e7, 2017 Feb.
[Is] ISSN:1534-4436
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Food allergy is an important public health problem because it affects children and adults, can be severe and even life-threatening, and may be increasing in prevalence. Beginning in 2008, the National Institute of Allergy and Infectious Diseases, working with other organizations and advocacy groups, led the development of the first clinical guidelines for the diagnosis and management of food allergy. A recent landmark clinical trial and other emerging data suggest that peanut allergy can be prevented through introduction of peanut-containing foods beginning in infancy. OBJECTIVES: Prompted by these findings, along with 25 professional organizations, federal agencies, and patient advocacy groups, the National Institute of Allergy and Infectious Diseases facilitated development of addendum guidelines to specifically address the prevention of peanut allergy. RESULTS: The addendum provides 3 separate guidelines for infants at various risk levels for the development of peanut allergy and is intended for use by a wide variety of health care providers. Topics addressed include the definition of risk categories, appropriate use of testing (specific IgE measurement, skin prick tests, and oral food challenges), and the timing and approaches for introduction of peanut-containing foods in the health care provider's office or at home. The addendum guidelines provide the background, rationale, and strength of evidence for each recommendation. CONCLUSIONS: Guidelines have been developed for early introduction of peanut-containing foods into the diets of infants at various risk levels for peanut allergy.
[Mh] Termos MeSH primário: Hipersensibilidade a Amendoim/prevenção & controle
[Mh] Termos MeSH secundário: Feminino
Seres Humanos
National Institute of Allergy and Infectious Diseases (U.S.)
Hipersensibilidade a Amendoim/diagnóstico
Hipersensibilidade a Amendoim/terapia
Estados Unidos
[Pt] Tipo de publicação:JOURNAL ARTICLE; PRACTICE GUIDELINE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170808
[Lr] Data última revisão:
170808
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170110
[St] Status:MEDLINE


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[PMID]:28065278
[Au] Autor:Togias A; Cooper SF; Acebal ML; Assa'ad A; Baker JR; Beck LA; Block J; Byrd-Bredbenner C; Chan ES; Eichenfield LF; Fleischer DM; Fuchs GJ; Furuta GT; Greenhawt MJ; Gupta RS; Habich M; Jones SM; Keaton K; Muraro A; Plaut M; Rosenwasser LJ; Rotrosen D; Sampson HA; Schneider LC; Sicherer SH; Sidbury R; Spergel J; Stukus DR; Venter C; Boyce JA
[Ad] Endereço:National Institute of Allergy and Infectious Diseases, Bethesda, Md.
[Ti] Título:Addendum guidelines for the prevention of peanut allergy in the United States: Report of the National Institute of Allergy and Infectious Diseases-sponsored expert panel.
[So] Source:J Allergy Clin Immunol;139(1):29-44, 2017 Jan.
[Is] ISSN:1097-6825
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Food allergy is an important public health problem because it affects children and adults, can be severe and even life-threatening, and may be increasing in prevalence. Beginning in 2008, the National Institute of Allergy and Infectious Diseases, working with other organizations and advocacy groups, led the development of the first clinical guidelines for the diagnosis and management of food allergy. A recent landmark clinical trial and other emerging data suggest that peanut allergy can be prevented through introduction of peanut-containing foods beginning in infancy. OBJECTIVES: Prompted by these findings, along with 25 professional organizations, federal agencies, and patient advocacy groups, the National Institute of Allergy and Infectious Diseases facilitated development of addendum guidelines to specifically address the prevention of peanut allergy. RESULTS: The addendum provides 3 separate guidelines for infants at various risk levels for the development of peanut allergy and is intended for use by a wide variety of health care providers. Topics addressed include the definition of risk categories, appropriate use of testing (specific IgE measurement, skin prick tests, and oral food challenges), and the timing and approaches for introduction of peanut-containing foods in the health care provider's office or at home. The addendum guidelines provide the background, rationale, and strength of evidence for each recommendation. CONCLUSIONS: Guidelines have been developed for early introduction of peanut-containing foods into the diets of infants at various risk levels for peanut allergy.
[Mh] Termos MeSH primário: Hipersensibilidade a Amendoim/prevenção & controle
[Mh] Termos MeSH secundário: Alérgenos/imunologia
Arachis/imunologia
Eczema/diagnóstico
Hipersensibilidade a Ovo/diagnóstico
Seres Humanos
Imunoglobulina E/sangue
Lactente
National Institute of Allergy and Infectious Diseases (U.S.)
Hipersensibilidade a Amendoim/sangue
Hipersensibilidade a Amendoim/diagnóstico
Testes Cutâneos
Estados Unidos
[Pt] Tipo de publicação:JOURNAL ARTICLE; PRACTICE GUIDELINE
[Nm] Nome de substância:
0 (Allergens); 37341-29-0 (Immunoglobulin E)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170719
[Lr] Data última revisão:
170719
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170110
[St] Status:MEDLINE


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[PMID]:28054723
[Au] Autor:Togias A; Cooper SF; Acebal ML; Assa'ad A; Baker JR; Beck LA; Block J; Byrd-Bredbenner C; Chan ES; Eichenfield LF; Fleischer DM; Fuchs GJ; Furuta GT; Greenhawt MJ; Gupta RS; Habich M; Jones SM; Keaton K; Muraro A; Plaut M; Rosenwasser LJ; Rotrosen D; Sampson HA; Schneider LC; Sicherer SH; Sidbury R; Spergel J; Stukus DR; Venter C; Boyce JA
[Ad] Endereço:The National Institute of Allergy and Infectious Diseases, Bethesda, Maryland.
[Ti] Título:Addendum Guidelines for the Prevention of Peanut Allergy in the United States: Report of the National Institute of Allergy and Infectious Diseases-Sponsored Expert Panel.
[So] Source:Pediatr Dermatol;34(1):e1-e21, 2017 Jan.
[Is] ISSN:1525-1470
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Food allergy is an important public health problem because it affects children and adults, can be severe and even life-threatening, and may be increasing in prevalence. Beginning in 2008, the National Institute of Allergy and Infectious Diseases, working with other organizations and advocacy groups, led the development of the first clinical guidelines for the diagnosis and management of food allergy. A recent landmark clinical trial and other emerging data suggest that peanut allergy can be prevented through introduction of peanut-containing foods beginning in infancy. OBJECTIVES: Prompted by these findings, along with 25 professional organizations, federal agencies, and patient advocacy groups, the National Institute of Allergy and Infectious Diseases facilitated development of addendum guidelines to specifically address the prevention of peanut allergy. RESULTS: The addendum provides three separate guidelines for infants at various risk levels for the development of peanut allergy and is intended for use by a wide variety of health care providers. Topics addressed include the definition of risk categories, appropriate use of testing (specific IgE measurement, skin prick tests, and oral food challenges), and the timing and approaches for introduction of peanut-containing foods in the health care provider's office or at home. The addendum guidelines provide the background, rationale, and strength of evidence for each recommendation. CONCLUSIONS: Guidelines have been developed for early introduction of peanut-containing foods into the diets of infants at various risk levels for peanut allergy.
[Mh] Termos MeSH primário: Arachis/imunologia
Hipersensibilidade a Amendoim/prevenção & controle
[Mh] Termos MeSH secundário: Criança
Seres Humanos
Lactente
National Institute of Allergy and Infectious Diseases (U.S.)
Fatores de Risco
Testes Cutâneos
Estados Unidos
[Pt] Tipo de publicação:JOURNAL ARTICLE; PRACTICE GUIDELINE
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170427
[Lr] Data última revisão:
170427
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170106
[St] Status:MEDLINE
[do] DOI:10.1111/pde.13093



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