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[PMID]:28427371
[Au] Autor:Al-Rousan T; Rubenstein L; Sieleni B; Deol H; Wallace RB
[Ad] Endereço:Department of Global Health, Harvard T.H. Chan School of Public Health, 665 Huntington Avenue, Building 1, Room 1107, Boston, MA, 02115, USA. talarousan@gmail.com.
[Ti] Título:Inside the nation's largest mental health institution: a prevalence study in a state prison system.
[So] Source:BMC Public Health;17(1):342, 2017 Apr 20.
[Is] ISSN:1471-2458
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The United States has the highest incarceration rate in the world which has created a public health crisis. Correctional facilities have become a front line for mental health care. Public health research in this setting could inform criminal justice reform. We determined prevalence rates for mental illnesses and related comorbidities among all inmates in a state prison system. METHODS: Cross-sectional study using the Iowa Corrections Offender Network which contains health records of all inmates in Iowa. The point prevalence of both ICD-9 and DSM-IV codes for mental illnesses, timing of diagnosis and interval between incarceration and mental illness diagnosis were determined. RESULTS: The average inmate (N = 8574) age was 36.7 ± 12.4 years; 17% were ≥50 years. The majority of inmates were men (91%) and white (65%).Obesity was prevalent in 38% of inmates, and 51% had a history of smoking. Almost half of inmates were diagnosed with a mental illness (48%), of whom, 29% had a serious mental illness (41% of all females and 27% of all males), and 26% had a history of a substance use disorder. Females had higher odds of having both a mental illness and substance use disorder. Almost all mental illness diagnoses were first made during incarceration (99%). The mean interval to diagnosis of depression, anxiety, PTSD and personality disorders were 26, 24, 21 and 29 months respectively. Almost 90% of mental illnesses were recognized by the 6 year of incarceration. The mean interval from incarceration to first diagnosis (recognition) of a substance abuse history was 11 months. CONCLUSIONS: There is a substantial burden of mental illness among inmates. Racial, age and gender disparities in mental health care are coupled with a general delay in diagnosis and treatment. A large part of understanding the mental health problem in this country starts at prisons.
[Mh] Termos MeSH primário: Transtornos Mentais/epidemiologia
Serviços de Saúde Mental/organização & administração
Prisioneiros/psicologia
Prisões/organização & administração
Transtornos Relacionados ao Uso de Substâncias/epidemiologia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Idoso de 80 Anos ou mais
Estudos Transversais
Manual Diagnóstico e Estatístico de Transtornos Mentais
Feminino
Seres Humanos
Classificação Internacional de Doenças
Iowa/epidemiologia
Masculino
Meia-Idade
National Institute of Mental Health (U.S.)
Prevalência
Estados Unidos
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170911
[Lr] Data última revisão:
170911
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170422
[St] Status:MEDLINE
[do] DOI:10.1186/s12889-017-4257-0


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[PMID]:28398574
[Au] Autor:Cohen AS; Le TP; Fedechko TL; Elvevåg B
[Ad] Endereço:Department of Psychology, Louisiana State University, Baton Rouge, LA, USA.
[Ti] Título:Can RDoC Help Find Order in Thought Disorder?
[So] Source:Schizophr Bull;43(3):503-508, 2017 05 01.
[Is] ISSN:1745-1701
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Thought disorder is a pernicious and nonspecific aspect of numerous serious mental illnesses (SMIs) and related conditions. Despite decades of empirical research on thought disorder, our present understanding of it is poor, our clinical assessments focus on a limited set of extreme behaviors, and treatments are palliative at best. Applying a Research Domain Criteria (RDoC) framework to thought disorder research offers advantages to explicate its phenotype; isolate its mechanisms; and develop more effective assessments, treatments, and potential cures. In this commentary, we discuss ways in which thought disorder can be understood within the RDoC framework. We propose operationalizing thought disorder within the RDoC construct of language using psycholinguistic sciences, to help objectify and quantify language within individuals; technologically sophisticated paradigms, to allow naturalistic behavioral sampling techniques with unprecedented ecological validity; and computational modeling, to account for a network of interconnected and dynamic linguistic, cognitive, affective, and social functions. We also highlight challenges for understanding thought disorder within an RDoC framework. Thought disorder likely does not occur as an isomorphic dysfunction in a single RDoC construct, but rather, as multiple potential dysfunctions in a network of RDoC constructs. Moreover, thought disorder is dynamic over time and context within individuals. In sum, RDoC is a useful framework to integrate multidisciplinary research efforts aimed at operationalizing, understanding, and ameliorating thought disorder.
[Mh] Termos MeSH primário: Transtornos Mentais/classificação
National Institute of Mental Health (U.S.)/normas
Pensamento/fisiologia
[Mh] Termos MeSH secundário: Seres Humanos
Estados Unidos
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170723
[Lr] Data última revisão:
170723
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170412
[St] Status:MEDLINE
[do] DOI:10.1093/schbul/sbx030


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[PMID]:28291038
[Au] Autor:Plakun EM
[Ad] Endereço:PLAKUN: Associate Medical Director, Director of Biopsychosocial Advocacy, Austen Riggs Center, Stockbridge, MA, and Leader, the American Psychiatric Association Psychotherapy Caucus, Arlington, VA.
[Ti] Título:Psychotherapy Research and the NIMH: An Either/Or or Both/And Research Agenda?
[So] Source:J Psychiatr Pract;23(2):130-133, 2017 Mar.
[Is] ISSN:1538-1145
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:There is a need for psychotherapy research to determine the effective, nonspecific or shared elements of psychotherapy regardless of therapy school. In an apparent "either/or" rather than "both/and" choice, the National Institute of Mental Health (NIMH) has committed its research resources to study of neural mechanisms and biomarkers, while greatly reducing funding for research into clinical methods, including psychotherapy. This column explores the potential effect of this decision on patient care and reviews questions raised by some about whether the underlying "big idea" behind the NIMH research approach is supported by the results of several decades of brain and genomics research. Patients are left to hope for clinically meaningful research findings concerning brain or gene mechanisms of mental disorders, as if they are just around the corner, when the actual benefit of such research likely remains decades away.
[Mh] Termos MeSH primário: Pesquisa Biomédica/normas
National Institute of Mental Health (U.S.)/normas
Psicoterapia
[Mh] Termos MeSH secundário: Pesquisa Biomédica/economia
Seres Humanos
National Institute of Mental Health (U.S.)/economia
Estados Unidos
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171004
[Lr] Data última revisão:
171004
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170315
[St] Status:MEDLINE
[do] DOI:10.1097/PRA.0000000000000217


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[PMID]:28253735
[Au] Autor:Walkup JT
[Ad] Endereço:From the Department of Psychiatry, Weill Cornell Medicine and New York-Presbyterian, New York.
[Ti] Título:Antidepressant Efficacy for Depression in Children and Adolescents: Industry- and NIMH-Funded Studies.
[So] Source:Am J Psychiatry;174(5):430-437, 2017 May 01.
[Is] ISSN:1535-7228
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Significant controversy surrounds the efficacy of the newer antidepressants for children and adolescents with depression. The controversy largely hinges on meta-analyses of studies that suggest that antidepressants are minimally effective, not effective, or equivalent to placebo. In this review, the author discusses several scientific and clinical complexities that are important to understand in reviewing the antidepressant literature: the strengths and weaknesses of meta-analyses; the scientific and regulatory context for the large number of antidepressant trials in the late 1990s and early 2000s; and the distinction between a negative trial, where the treatment does not demonstrate efficacy, and a failed trial, where methodological problems make it impossible to draw any conclusion about efficacy. It is the premise of this review that meta-analyses that include the large number of industry-sponsored antidepressant trials distort the picture of antidepressant efficacy for teen depression. Industry-sponsored child and adolescent depression trials suffer from a number of implementation challenges and should be considered failed trials that are largely uninformative and not eligible to be included in efficacy meta-analyses. In contrast to the industry-sponsored trials, depression trials funded by the National Institute of Mental Health (NIMH) (N=2) are characterized by many methodological strengths, lower placebo response rates (30%-35%), and meaningful between-group differences (25%-30%) that support antidepressant efficacy. The NIMH-funded trials, taken together with the demonstrated efficacy of the serotonin reuptake inhibitors for childhood-onset obsessive-compulsive disorder and the anxiety disorders, suggest a broad and important role for antidepressant medications in pediatric internalizing conditions.
[Mh] Termos MeSH primário: Antidepressivos/uso terapêutico
Transtorno Depressivo/tratamento farmacológico
Indústria Farmacêutica
Financiamento Governamental
Organização do Financiamento
National Institute of Mental Health (U.S.)
Apoio à Pesquisa como Assunto
[Mh] Termos MeSH secundário: Adolescente
Antidepressivos/efeitos adversos
Transtornos de Ansiedade/tratamento farmacológico
Criança
Ensaios Clínicos como Assunto
Transtorno Depressivo/diagnóstico
Transtorno Depressivo/psicologia
Seres Humanos
Metanálise como Assunto
Transtorno Obsessivo-Compulsivo/tratamento farmacológico
Projetos de Pesquisa
Inibidores da Captação de Serotonina/uso terapêutico
Falha de Tratamento
Resultado do Tratamento
Estados Unidos
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Antidepressive Agents); 0 (Serotonin Uptake Inhibitors)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170619
[Lr] Data última revisão:
170619
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170304
[St] Status:MEDLINE
[do] DOI:10.1176/appi.ajp.2017.16091059


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[PMID]:28002661
[Au] Autor:Yager J; Feinstein RE
[Ad] Endereço:Department of Psychiatry, MC A011-04, University of Colorado School of Medicine, 13001 East 17th Pl, Aurora, CO 80045. joel.yager@ucdenver.edu.
[Ti] Título:Potential Applications of the National Institute of Mental Health's Research Domain Criteria (RDoC) to Clinical Psychiatric Practice: How RDoC Might Be Used in Assessment, Diagnostic Processes, Case Formulation, Treatment Planning, and Clinical Notes.
[So] Source:J Clin Psychiatry;78(4):423-432, 2017 Apr.
[Is] ISSN:1555-2101
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Offering a new framework for understanding and studying basic dimensions of normal and abnormal human functioning and mental disorders, the National Institute of Mental Health (NIMH) has initiated the Research Domain Criteria (RDoC) project in which a series of higher order domains, representing major systems of emotion, cognition, motivation, and social behavior, and their constituent operationally defined constructs serve as organizing templates for further research and inquiry, eg, to discover validated biomarkers and endophenotypes. Cutting across traditional DSM diagnoses, the domains are defined as Negative Valence Systems, Positive Valence Systems, Cognitive Systems, Systems for Social Processes, and Arousal/Regulatory Systems. To inform educators, trainees, and practitioners about RDoC, alert them to potential practical applications, and encourage their broad exploration in clinical settings, this article reviews the RDoC domains and their subsystem constructs with regard to potential current clinical considerations and applications. We describe ways in which the RDoC domains and constructs offer transdiagnostic frameworks for complementing traditional practice; suggest clinical questions to help elucidate salient information; and, translating RDoC domains and constructs headings into clinically friendly language, offer a template for the psychiatric review of systems that can serve in clinical notes.
[Mh] Termos MeSH primário: Transtornos Mentais/diagnóstico
Transtornos Mentais/terapia
National Institute of Mental Health (U.S.)/normas
Planejamento de Assistência ao Paciente
[Mh] Termos MeSH secundário: Seres Humanos
Transtornos Mentais/classificação
Estados Unidos
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170630
[Lr] Data última revisão:
170630
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161222
[St] Status:MEDLINE
[do] DOI:10.4088/JCP.15nr10476


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[PMID]:27859320
[Au] Autor:Cheadle C; Cao H; Kalinin A; Hodgkinson J
[Ad] Endereço:Department of Genomics Research, R&D Solutions, Rockville, Maryland.
[Ti] Título:Advanced literature analysis in a Big Data world.
[So] Source:Ann N Y Acad Sci;1387(1):25-33, 2017 Jan.
[Is] ISSN:1749-6632
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Comprehensive data mining of the scientific literature has become an increasing challenge. To address this challenge, Elsevier's Pathway Studio software uses the techniques of natural language processing to systematically extract specific biological information from journal articles and abstracts that is then used to create a very large, structured, and constantly expanding literature knowledgebase. Highly sophisticated visualization tools allow the user to interactively explore the vast number of connections created and stored in the Pathway Studio database. We demonstrate the value of this structured information approach by way of a biomarker use case example and describe a comprehensive collection of biomarkers and biomarker candidates, as reported in the literature. We use four major neuropsychiatric diseases to demonstrate common and unique biomarker elements, demonstrate specific enrichment patterns, and highlight strategies for identifying the most recent and novel reports for potential biomarker discovery. Finally, we introduce an innovative new taxonomy based on brain region identifications, which greatly increases the potential depth and complexity of information retrieval related to, and now accessible for, neuroscience research.
[Mh] Termos MeSH primário: Pesquisa Biomédica/métodos
Biologia Computacional/métodos
Mineração de Dados/métodos
Sistemas de Gerenciamento de Base de Dados
Programas de Rastreamento/métodos
Transtornos Mentais/diagnóstico
Processamento de Linguagem Natural
[Mh] Termos MeSH secundário: Resumos e Indexação como Assunto
Animais
Transtornos de Ansiedade/classificação
Transtornos de Ansiedade/diagnóstico
Transtornos de Ansiedade/metabolismo
Transtornos de Ansiedade/terapia
Biomarcadores/metabolismo
Pesquisa Biomédica/tendências
Transtorno Bipolar/classificação
Transtorno Bipolar/diagnóstico
Transtorno Bipolar/metabolismo
Transtorno Bipolar/terapia
Biologia Computacional/tendências
Mineração de Dados/tendências
Sistemas de Gerenciamento de Base de Dados/tendências
Bases de Dados Bibliográficas
Transtorno Depressivo Maior/classificação
Transtorno Depressivo Maior/diagnóstico
Transtorno Depressivo Maior/metabolismo
Transtorno Depressivo Maior/terapia
Seres Humanos
Programas de Rastreamento/tendências
Transtornos Mentais/classificação
Transtornos Mentais/metabolismo
Transtornos Mentais/terapia
National Institute of Mental Health (U.S.)
Publicações Periódicas como Assunto
Prognóstico
Esquizofrenia/classificação
Esquizofrenia/diagnóstico
Esquizofrenia/metabolismo
Esquizofrenia/terapia
Software
Pesquisa Médica Translacional/métodos
Pesquisa Médica Translacional/tendências
Estados Unidos
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Biomarkers)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170731
[Lr] Data última revisão:
170731
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161119
[St] Status:MEDLINE
[do] DOI:10.1111/nyas.13270


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[PMID]:27828875
[Au] Autor:Fogel JM; Clarke W; Kulich M; Piwowar-Manning E; Breaud A; Olson MT; Marzinke MA; Laeyendecker O; Fiamma A; Donnell D; Mbwambo JK; Richter L; Gray G; Sweat M; Coates TJ; Eshleman SH
[Ad] Endereço:*Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD; †Department of Probability and Statistics, Faculty of Mathematics and Physics, Charles University, Prague, Czech Republic; ‡Laboratory of Immunoregulation, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Baltimore, MD; §Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD; ‖Program in Global Health, University of California at Los Angeles, Los Angeles, CA; ¶Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA; #Department of Global Health, University of Washington, Seattle, WA; **Muhimbili University of Health and Allied Sciences, Muhimbili University Teaching Hospital, Dar es Salaam, Tanzania; ††DST-NRF Centre of Excellence in Human Development, University of the Witwatersrand, Johannesburg, South Africa; ‡‡Perinatal HIV Research Unit, Chris Hani Baragwanath Hospital, University of the Witwatersrand, Johannesburg, South Africa; §§South African Medical Research Council, Cape Town, South Africa; ‖‖Department of Psychiatry and Behavioral Sciences, The Medical University of South Carolina, Charleston, SC; and ¶¶Center for World Health, David Geffen School of Medicine and UCLA Health, Los Angeles, CA.
[Ti] Título:Antiretroviral Drug Use in a Cross-Sectional Population Survey in Africa: NIMH Project Accept (HPTN 043).
[So] Source:J Acquir Immune Defic Syndr;74(2):158-165, 2017 Feb 01.
[Is] ISSN:1944-7884
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Antiretroviral (ARV) drug treatment benefits the treated individual and can prevent HIV transmission. We assessed ARV drug use in a community-randomized trial that evaluated the impact of behavioral interventions on HIV incidence. METHODS: Samples were collected in a cross-sectional survey after a 3-year intervention period. ARV drug testing was performed using samples from HIV-infected adults at 4 study sites (Zimbabwe; Tanzania; KwaZulu-Natal and Soweto, South Africa; survey period 2009-2011) using an assay that detects 20 ARV drugs (6 nucleoside/nucleotide reverse transcriptase inhibitors, 3 nonnucleoside reverse transcriptase inhibitors, and 9 protease inhibitors; maraviroc; raltegravir). RESULTS: ARV drugs were detected in 2011 (27.4%) of 7347 samples; 88.1% had 1 nonnucleoside reverse transcriptase inhibitors ± 1-2 nucleoside/nucleotide reverse transcriptase inhibitors. ARV drug detection was associated with sex (women>men), pregnancy, older age (>24 years), and study site (P < 0.0001 for all 4 variables). ARV drugs were also more frequently detected in adults who were widowed (P = 0.006) or unemployed (P = 0.02). ARV drug use was more frequent in intervention versus control communities early in the survey (P = 0.01), with a significant increase in control (P = 0.004) but not in intervention communities during the survey period. In KwaZulu-Natal, a 1% increase in ARV drug use was associated with a 0.14% absolute decrease in HIV incidence (P = 0.018). CONCLUSIONS: This study used an objective, biomedical approach to assess ARV drug use on a population level. This analysis identified factors associated with ARV drug use and provided information on ARV drug use over time. ARV drug use was associated with lower HIV incidence at 1 study site.
[Mh] Termos MeSH primário: Antirretrovirais/uso terapêutico
Uso de Medicamentos
Infecções por HIV/tratamento farmacológico
Infecções por HIV/prevenção & controle
[Mh] Termos MeSH secundário: Adolescente
Adulto
África
Estudos Transversais
Feminino
Seres Humanos
Masculino
National Institute of Mental Health (U.S.)
Gravidez
Ensaios Clínicos Controlados Aleatórios como Assunto
Estudos Retrospectivos
Estados Unidos
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Retroviral Agents)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170909
[Lr] Data última revisão:
170909
[Sb] Subgrupo de revista:IM; X
[Da] Data de entrada para processamento:161110
[St] Status:MEDLINE
[do] DOI:10.1097/QAI.0000000000001229


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[PMID]:27196537
[Au] Autor:Savage JE; Sawyers C; Roberson-Nay R; Hettema JM
[Ad] Endereço:Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Virginia.
[Ti] Título:The genetics of anxiety-related negative valence system traits.
[So] Source:Am J Med Genet B Neuropsychiatr Genet;174(2):156-177, 2017 Mar.
[Is] ISSN:1552-485X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:NIMH's Research Domain Criteria (RDoC) domain of negative valence systems (NVS) captures constructs of negative affect such as fear and distress traditionally subsumed under the various internalizing disorders. Through its aims to capture dimensional measures that cut across diagnostic categories and are linked to underlying neurobiological systems, a large number of phenotypic constructs have been proposed as potential research targets. Since "genes" represent a central "unit of analysis" in the RDoC matrix, it is important for studies going forward to apply what is known about the genetics of these phenotypes as well as fill in the gaps of existing knowledge. This article reviews the extant genetic epidemiological data (twin studies, heritability) and molecular genetic association findings for a broad range of putative NVS phenotypic measures. We find that scant genetic epidemiological data is available for experimentally derived measures such as attentional bias, peripheral physiology, or brain-based measures of threat response. The molecular genetic basis of NVS phenotypes is in its infancy, since most studies have focused on a small number of candidate genes selected for putative association to anxiety disorders (ADs). Thus, more research is required to provide a firm understanding of the genetic aspects of anxiety-related NVS constructs. © 2016 Wiley Periodicals, Inc.
[Mh] Termos MeSH primário: Transtornos de Ansiedade/epidemiologia
Transtornos de Ansiedade/genética
Ansiedade/fisiopatologia
[Mh] Termos MeSH secundário: Afeto
Ansiedade/epidemiologia
Ansiedade/genética
Encéfalo/fisiopatologia
Seres Humanos
National Institute of Mental Health (U.S.)
Fenótipo
Locos de Características Quantitativas/genética
Pesquisa/normas
Estados Unidos
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170726
[Lr] Data última revisão:
170726
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160520
[St] Status:MEDLINE
[do] DOI:10.1002/ajmg.b.32459


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[PMID]:27808211
[Au] Autor:Abbott A
[Ti] Título:US mental-health chief: psychiatry must get serious about mathematics.
[So] Source:Nature;539(7627):18-19, 2016 11 03.
[Is] ISSN:1476-4687
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Pesquisa Biomédica/tendências
Matemática
National Institute of Mental Health (U.S.)/organização & administração
Vias Neurais
Neurociências/tendências
Psiquiatria/tendências
[Mh] Termos MeSH secundário: Bem-Estar do Animal
Animais
Pesquisa Biomédica/organização & administração
Conectoma
Estimulação Encefálica Profunda
Voluntários Saudáveis
Seres Humanos
Comunicação Interdisciplinar
Transtornos Mentais/genética
Transtornos Mentais/patologia
Transtornos Mentais/terapia
Camundongos
Modelos Animais
National Institute of Mental Health (U.S.)/economia
National Institute of Mental Health (U.S.)/tendências
Neurociências/métodos
Optogenética
Primatas
Estimulação Magnética Transcraniana
Estados Unidos
[Pt] Tipo de publicação:INTERVIEW
[Em] Mês de entrada:1611
[Cu] Atualização por classe:161230
[Lr] Data última revisão:
161230
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161104
[St] Status:MEDLINE
[do] DOI:10.1038/nature.2016.20893


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[PMID]:27789821
[Au] Autor:Wadman M
[Ti] Título:Mental health chief to stress neural circuits.
[So] Source:Science;354(6311):403, 2016 Oct 28.
[Is] ISSN:1095-9203
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Saúde Mental
National Institute of Mental Health (U.S.)/tendências
Vias Neurais
Neurociências/tendências
[Mh] Termos MeSH secundário: Seres Humanos
National Institute of Mental Health (U.S.)/economia
Estados Unidos
[Pt] Tipo de publicação:INTERVIEW
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170413
[Lr] Data última revisão:
170413
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161030
[St] Status:MEDLINE



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BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde