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[PMID]: 29446881 [Au] Autor: Clémençon R [Ad] Endereço: University of California, Santa Barbara, California, USA. [Ti] Título: "Zweckoptimismus" and the Paris process will not save the world from climate catastrophe. [So] Source: Integr Environ Assess Manag;14(2):198-201, 2018 Mar. [Is] ISSN: 1551-3793 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: Politicians, government officials, business representatives, and nongovernmental climate activists all in various ways emphasize what they see as progress being made in the aftermath of the Paris Agreement, even if they continue to warn of the dire consequences of business as usual. Indeed, there is no lack of encouraging private and public sector initiatives on climate change. Some macro trends seem to be moving in the right direction, as well. But, closer scrutiny shows that these positive trends are still far from adding up to the necessary fundamental shift in the global energy economy. Furthermore, the public may greatly overestimate the advancement of renewable solar and wind energy technology, which contributes to a false sense of progress and lessens political urgency. Without determined and reinvigorated political leadership from the European Union (EU), there is little hope that necessary emission reduction goals to stay below 2 °C above preindustrial levels can be met. The EU has driven international climate policy from the beginning of climate negotiations, and there is unfortunately no other source of leadership in sight. It will require difficult political decisions to be taken sooner rather than later to force a much quicker domestic energy transition and to raise financing to help developing countries with their own energy transition and adaptation to a rapidly warming world. Integr Environ Assess Manag 2018;14:198-201. © 2018 SETAC. [Mh] Termos MeSH primário: Poluição do Ar/prevenção & controle Mudança Climática Política Ambiental Gases de Efeito Estufa/análise Cooperação Internacional [Mh] Termos MeSH secundário: Poluição do Ar/estatística & dados numéricos União Europeia Efeito Estufa Paris [Pt] Tipo de publicação: JOURNAL ARTICLE [Nm] Nome de substância: 0 (Greenhouse Gases) [Em] Mês de entrada: 1803 [Cu] Atualização por classe: 180308 [Lr] Data última revisão: 180308 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 180216 [St] Status: MEDLINE [do] DOI: 10.1002/ieam.2015

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[PMID]: 28942277 [Au] Autor: Pedrazzani R; Cavallotti I; Bollati E; Ferreri M; Bertanza G [Ad] Endereço: Department of Mechanical and Industrial Engineering, Università degli Studi di Brescia, via Branze 38, I-25123 Brescia, Italy; MISTRAL c/o DSMC - Università degli Studi di Brescia, Viale Europa, 11, I-25123 Brescia, Italy. Electronic address: roberta.pedrazzani@unibs.it. [Ti] Título: The role of bioassays in the evaluation of ecotoxicological aspects within the PEF/OEF protocols: The case of WWTPs. [So] Source: Ecotoxicol Environ Saf;147:742-748, 2018 Jan. [Is] ISSN: 1090-2414 [Cp] País de publicação: Netherlands [La] Idioma: eng [Ab] Resumo: The suitability evaluation of any industrial process should rely on economic, technical, social and, in particular, environmental aspects. The Commission Recommendation 2013/179/UE enables the improvement and the harmonization of the conventional evaluation of environmental footprints, such as LCA (Life Cycle Assessment), Carbon and Water Footprint, by suggesting the assessment of life cycle environmental performance of products and organisations (PEF, OEF). Novelty aspects reside in including new impact categories (namely, human toxicity cancer effects, human toxicity not-cancer effects and eco-toxicity). This paper presents an application of PEF/OEF protocol to the example case of an activated sludge wastewater treatment plant. Strengths and criticisms of this approach are discussed, by taking into consideration the possible final goal of the suitability assessment. Valuably, the adoption of bioassays (i.e., the input of their results in the models for calculating the life cycle environmental performance) for a more reliable evaluation of the impact on the ecosystem and human health is proposed. [Mh] Termos MeSH primário: Bioensaio Ecotoxicologia/métodos Política Ambiental/legislação & jurisprudência Regulamentação Governamental Purificação da Água/normas [Mh] Termos MeSH secundário: Bioensaio/métodos Bioensaio/normas Análise da Demanda Biológica de Oxigênio Ecossistema Ecotoxicologia/legislação & jurisprudência União Europeia Seres Humanos Modelos Teóricos Esgotos/análise Testes de Toxicidade/normas Águas Residuais/toxicidade Poluentes Químicos da Água/toxicidade Purificação da Água/legislação & jurisprudência [Pt] Tipo de publicação: JOURNAL ARTICLE [Nm] Nome de substância: 0 (Sewage); 0 (Waste Water); 0 (Water Pollutants, Chemical) [Em] Mês de entrada: 1803 [Cu] Atualização por classe: 180308 [Lr] Data última revisão: 180308 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170925 [St] Status: MEDLINE

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[PMID]: 27776380 [Au] Autor: Cristoni S; Dusi G; Brambilla P; Albini A; Conti M; Brambilla M; Bruno A; Di Gaudio F; Ferlin L; Tazzari V; Mengozzi S; Barera S; Sialer C; Trenti T; Cantu M; Rossi Bernardi L; Noonan DM [Ad] Endereço: I.S.B.-Ion Source & Biotechnologies, Bresso, Milano, Italy. [Ti] Título: SANIST: optimization of a technology for compound identification based on the European Union directive with applications in forensic, pharmaceutical and food analyses. [So] Source: J Mass Spectrom;52(1):16-21, 2017 01. [Is] ISSN: 1096-9888 [Cp] País de publicação: England [La] Idioma: eng [Ab] Resumo: Electrospray Ionization and collision induced dissociation tandem mass spectrometry are usually employed to obtain compound identification through a mass spectra match. Different algorithms have been developed for this purpose (for example the nist match algorithm). These approaches compare the tandem mass spectra of the unknown analyte with the tandem mass spectra spectra of known compounds inserted in a database. The compounds are usually identified on the basis of spectral match value associated with a probability of recognition. However, this approach is not usually applied to multiple reaction monitoring transition spectra achieved by means of triple quadrupole apparatus, mainly due to the lack of a transition spectra database. The Surface Activated Chemical Ionization-Electrospray-NIST Bayesian model database search (SANIST) platform has been recently developed for new potential metabolite biomarker discovery, to confirm their identity and to use them for clinical and diagnostic applications. Here, we present an improved version of the SANIST platform that extends its application to forensic, pharmaceutical, and food analysis studies, where the compound identification rules are strict. The European Union (EU) has set directives for compound identification (EU directive 2002/657/EC). We have applied the SANIST method to identification of 11-nor-9-carboxytetrahydro-cannabinol in urine samples (an example of a forensic application), circulating levels of the immunosuppressive drug tacrolimus in blood (an example of a pharmaceutical application) and glyphosate in fruit juice (an example of a food analysis application) that meet the EU directive requirements. Copyright © 2016 John Wiley & Sons, Ltd. [Mh] Termos MeSH primário: Biomarcadores/análise Espectrometria de Massas em Tandem/instrumentação Espectrometria de Massas em Tandem/métodos [Mh] Termos MeSH secundário: Algoritmos Teorema de Bayes Química Farmacêutica Cromatografia Líquida de Alta Pressão/métodos Bases de Dados Factuais União Europeia Análise de Alimentos Ciências Forenses Seres Humanos [Pt] Tipo de publicação: JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T [Nm] Nome de substância: 0 (Biomarkers) [Em] Mês de entrada: 1803 [Cu] Atualização por classe: 180307 [Lr] Data última revisão: 180307 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 161025 [St] Status: MEDLINE [do] DOI: 10.1002/jms.3895

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[PMID]: 29357381 [Au] Autor: Sala A [Ad] Endereço: Italian National Research Council (CNR), Institute of Marine Sciences (ISMAR), Ancona, Italy. [Ti] Título: Influence of tow duration on catch performance of trawl survey in the Mediterranean Sea. [So] Source: PLoS One;13(1):e0191662, 2018. [Is] ISSN: 1932-6203 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: The aim of this study was to assess the effect of tow duration on catch per unit of swept area (CPUE), trawl catch performance, and the proportion of the species caught in a trawl survey. Longer tows are expected to have a greater probability of catching species. An average of 26 species were caught in the first 30 minutes, whereas only about one additional species was caught in the next 30 minutes in longer tows. The shorter tows involved a decrement in catch weight for 11 of the 12 target species sampled, demonstrating that tow duration did affect catch per unit of swept area CPUE. The shorter tows were associated with a significant reduction of the overall CPUE in terms of weight of the main target species and of the total catch (circa 60%). The same strong reduction of around 70% was found in particular for European hake (Merluccius merluccius) and surmullet (Mullus spp) and 50% for Nephrops (Nephrops norvegicus). The shorter tows were less efficient in catching large-sized hake, surmullet, Nephrops, Atlantic horse mackerel (Trachurus trachurus), and poor cod (Trisopterus minutus), even though the difference was significant only for Nephrops. Regardless of the p-value statistic, these findings suggest that the continuity of survey time series would be severely impaired by changing tow duration. Further work is required to explore a way to reduce tow duration without reducing CPUE. [Mh] Termos MeSH primário: Pesqueiros Peixes [Mh] Termos MeSH secundário: Animais Tamanho Corporal União Europeia Pesqueiros/legislação & jurisprudência Pesqueiros/estatística & dados numéricos Peixes/anatomia & histologia Peixes/fisiologia Mar Mediterrâneo Recursos Naturais Densidade Demográfica Especificidade da Espécie Inquéritos e Questionários Natação Fatores de Tempo [Pt] Tipo de publicação: JOURNAL ARTICLE [Em] Mês de entrada: 1803 [Cu] Atualização por classe: 180302 [Lr] Data última revisão: 180302 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 180123 [St] Status: MEDLINE [do] DOI: 10.1371/journal.pone.0191662

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[PMID]: 29192033 [Au] Autor: Jarvis S [Ti] Título: Feeling it. [So] Source: Vet Rec;181(22):577, 2017 12. [Is] ISSN: 2042-7670 [Cp] País de publicação: England [La] Idioma: eng [Mh] Termos MeSH primário: Bem-Estar do Animal/legislação & jurisprudência Emoções Política [Mh] Termos MeSH secundário: Animais União Europeia Seres Humanos Reino Unido [Pt] Tipo de publicação: EDITORIAL [Em] Mês de entrada: 1803 [Cu] Atualização por classe: 180302 [Lr] Data última revisão: 180302 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 171202 [St] Status: MEDLINE [do] DOI: 10.1136/vr.j5585

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[PMID]: 29424973 [Au] Autor: Bourquard K; Orlova A; Parisot C [Ti] Título: Understanding User Needs for Interoperability: Defining Use Cases in eHealth. [So] Source: J AHIMA;88(6):42-5, 2017 06. [Is] ISSN: 1060-5487 [Cp] País de publicação: United States [La] Idioma: eng [Mh] Termos MeSH primário: Registros Eletrônicos de Saúde/organização & administração Gestão da Informação em Saúde/organização & administração Integração de Sistemas [Mh] Termos MeSH secundário: União Europeia Seres Humanos Disseminação de Informação Registro Médico Coordenado Determinação de Necessidades de Cuidados de Saúde Estados Unidos [Pt] Tipo de publicação: JOURNAL ARTICLE [Em] Mês de entrada: 1803 [Cu] Atualização por classe: 180301 [Lr] Data última revisão: 180301 [Sb] Subgrupo de revista: H [Da] Data de entrada para processamento: 180210 [St] Status: MEDLINE

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[PMID]: 29384744 [Au] Autor: Pradella F; Pinchi V; Focardi M; Grifoni R; Palandri M; Norelli GA [Ad] Endereço: Section of Medical Forensic Sciences, Department of Health Sciences, University of Florence, Italy. [Ti] Título: The age estimation practice related to illegal unaccompanied minors immigration in Italy. [So] Source: J Forensic Odontostomatol;2(35):147-156, 2017 Dec 01. [Is] ISSN: 2219-6749 [Cp] País de publicação: Australia [La] Idioma: eng [Ab] Resumo: The migrants arrived to the Italian coasts in 2016 were 181.436, 18% more than the previous year and 6% more than the highest number ever since. An "unaccompanied minor" (UAM) is a third-country national or a stateless person under eighteen years of age, who arrives on the territory of the Member State unaccompanied by an adult responsible for him/her whether by law or by the practice of the Member State concerned, and for as long as he or she is not effectively taken into the care of such a person; it includes a minor who is left unaccompanied after he/she entered the territory of the Member States. As many as 95.985 UAMs applied for international protection in an EU member country just in 2015, almost four times the number registered in the previous year. The UAMs arrived in Italy were 28.283 in 2016; 94% of them were males, 92% unaccompanied, 8% of them under 15; the 53,6% is 17; the individuals between 16 and 17 are instead the 82%. Many of them (50%), 6561 in 2016, escaped from the sanctuaries, thus avoiding to be formally identified and registered in Italy in the attempt to reach more easily northern Europe countries, since The Dublin Regulations (2003) state that the asylum application should be held in the EU country of entrance or where parents reside. The age assessment procedures can therefore be considered as a relevant task that weighs in on the shoulders of the forensic experts with all the related issues and the coming of age is the important threshold. In the EU laws on asylum, the minors are considered as one of the groups of vulnerable persons towards whom Member States have specific obligations. A proper EU common formal regulation in the matter of age estimation procedures still lacks. According to the Italian legal framework in the matter, a medical examination should have been always performed but a new law completely changed the approach to the procedures of age estimation of the migrant (excluding the criminal cases) with a better adherence to the notions and concepts of vulnerability and psychological and social maturity. [Mh] Termos MeSH primário: Determinação da Idade pelo Esqueleto Determinação da Idade pelos Dentes Menores de Idade/legislação & jurisprudência Refugiados/legislação & jurisprudência Migrantes/legislação & jurisprudência [Mh] Termos MeSH secundário: União Europeia Seres Humanos [Pt] Tipo de publicação: JOURNAL ARTICLE [Em] Mês de entrada: 1802 [Cu] Atualização por classe: 180221 [Lr] Data última revisão: 180221 [Sb] Subgrupo de revista: D [Da] Data de entrada para processamento: 180201 [St] Status: MEDLINE

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[PMID]: 29381928 [Au] Autor: Liao N; Zhao H; Chen ML; Xie ZF [Ad] Endereço: Department of Geriatrics and Gerontology, First Affiliated Hospital, Guangxi Medical University, Nanning, China. [Ti] Título: Association of the IL-13 polymorphisms rs1800925 and rs20541 with chronic obstructive pulmonary disease risk: An updated meta-analysis. [So] Source: Medicine (Baltimore);96(47):e8556, 2017 Nov. [Is] ISSN: 1536-5964 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: The aim of this study was to investigate if 2 common single nucleotide polymorphisms (SNPs) in the interleukin-13 (IL-13) gene, rs1800925 and rs20541 are associated with chronic obstructive pulmonary disease (COPD) risk.Case-control association studies were retrieved systematically from PubMed, Scopus, ISI Web of Science, China National Knowledge Infrastructure, and Wanfang databases using standardized subject terms.Eleven studies including 3077 participants (1896 cases and 1181 controls) were analyzed. Evidence for a positive association between the T allele of the IL-13 SNP rs1800925 and COPD risk was found in the overall population (odds ratio [OR] = 1.57, 95% confidence interval [95% CI]: 1.21-2.04, Pz = .001). In subgroup analysis according to ethnicity, the T allele of rs1800925 was associated with an increased risk of COPD in Asians (OR = 1.88, 95% CI: 1.23-2.87, Pz = .004) and Caucasians (OR = 1.30, 95% CI: 1.01-1.67, Pz = .041), respectively. For rs20541, the results suggested an association between rs20541 and COPD risk in Caucasians under the recessive model (OR = 2.79, 95% CI: 1.13-6.92, Pz = .026), whereas this SNP was not associated with COPD in Asians.This meta-analysis suggests that the T allele of rs1800925 is associated with the increased risk of COPD in both Asians and Caucasians, whereas rs20541 is associated with the risk of COPD in Caucasians but not in Asians. [Mh] Termos MeSH primário: Interleucina-13/genética Doença Pulmonar Obstrutiva Crônica/genética [Mh] Termos MeSH secundário: Grupo com Ancestrais do Continente Asiático/genética Estudos de Casos e Controles China Grupos Étnicos Grupo com Ancestrais do Continente Europeu/genética União Europeia Predisposição Genética para Doença Seres Humanos Razão de Chances Polimorfismo de Nucleotídeo Único Doença Pulmonar Obstrutiva Crônica/etnologia [Pt] Tipo de publicação: JOURNAL ARTICLE; META-ANALYSIS [Nm] Nome de substância: 0 (Interleukin-13) [Em] Mês de entrada: 1802 [Cu] Atualização por classe: 180220 [Lr] Data última revisão: 180220 [Sb] Subgrupo de revista: AIM; IM [Da] Data de entrada para processamento: 180201 [St] Status: MEDLINE [do] DOI: 10.1097/MD.0000000000008556

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[PMID]: 29359899 [Au] Autor: Berry MD [Ad] Endereço: Thomson Reuters Accelus. [Ti] Título: Business of Health: International Healthcare. [So] Source: Issue Brief Health Policy Track Serv;2017:1-66, 2017 Dec 26. [Cp] País de publicação: United States [La] Idioma: eng [Mh] Termos MeSH primário: Assistência à Saúde/organização & administração Saúde Global [Mh] Termos MeSH secundário: Aborto Legal África Américas Ásia Ensaios Clínicos como Assunto Aprovação de Drogas Custos de Medicamentos Indústria Farmacêutica Europa (Continente) União Europeia Custos de Cuidados de Saúde Reforma dos Serviços de Saúde/organização & administração Seres Humanos Seguro Saúde Mortalidade Materna Oriente Médio Política [Pt] Tipo de publicação: JOURNAL ARTICLE [Em] Mês de entrada: 1802 [Cu] Atualização por classe: 180219 [Lr] Data última revisão: 180219 [Sb] Subgrupo de revista: T [Da] Data de entrada para processamento: 180124 [St] Status: MEDLINE

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[PMID]: 29298300 [Au] Autor: Woodcock BA; Ridding L; Freeman SN; Pereira MG; Sleep D; Redhead J; Aston D; Carreck NL; Shore RF; Bullock JM; Heard MS; Pywell RF [Ad] Endereço: NERC Centre for Ecology & Hydrology, Wallingford, Oxfordshire, United Kingdom. [Ti] Título: Neonicotinoid residues in UK honey despite European Union moratorium. [So] Source: PLoS One;13(1):e0189681, 2018. [Is] ISSN: 1932-6203 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: Due to concerns over negative impacts on insect pollinators, the European Union has implemented a moratorium on the use of three neonicotinoid pesticide seed dressings for mass-flowering crops. We assessed the effectiveness of this policy in reducing the exposure risk to honeybees by collecting 130 samples of honey from bee keepers across the UK before (2014: N = 21) and after the moratorium was in effect (2015: N = 109). Neonicotinoids were present in about half of the honey samples taken before the moratorium, and they were present in over a fifth of honey samples following the moratorium. Clothianidin was the most frequently detected neonicotinoid. Neonicotinoid concentrations declined from May to September in the year following the ban. However, the majority of post-moratorium neonicotinoid residues were from honey harvested early in the year, coinciding with oilseed rape flowering. Neonicotinoid concentrations were correlated with the area of oilseed rape surrounding the hive location. These results suggest mass flowering crops may contain neonicotinoid residues where they have been grown on soils contaminated by previously seed treated crops. This may include winter seed treatments applied to cereals that are currently exempt from EU restrictions. Although concentrations of neonicotinoids were low (<2.0 ng g-1), and posed no risk to human health, they may represent a continued risk to honeybees through long-term chronic exposure. [Mh] Termos MeSH primário: Mel/análise Neonicotinoides/análise Resíduos de Praguicidas/análise [Mh] Termos MeSH secundário: Produtos Agrícolas União Europeia Reino Unido [Pt] Tipo de publicação: JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T [Nm] Nome de substância: 0 (Neonicotinoids); 0 (Pesticide Residues) [Em] Mês de entrada: 1802 [Cu] Atualização por classe: 180210 [Lr] Data última revisão: 180210 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 180104 [St] Status: MEDLINE [do] DOI: 10.1371/journal.pone.0189681

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