[PMID]: | 29296106 |
[Au] Autor: | Seifert JG; Brumet A; St Cyr JA |
[Ad] Endereço: | Movement Science Laboratory, Montana State University, Bozeman, MT USA. |
[Ti] Título: | The influence of D-ribose ingestion and fitness level on performance and recovery. |
[So] Source: | J Int Soc Sports Nutr;14:47, 2017. |
[Is] ISSN: | 1550-2783 |
[Cp] País de publicação: | United States |
[La] Idioma: | eng |
[Ab] Resumo: | Background: Skeletal muscle adenosine triphosphate (ATP) levels are severely depleted during and following prolonged high intensity exercise. Recovery from these lower ATP levels can take days, which can affect performance on subsequent days of exercise. Untrained individuals often suffer the stress and consequences of acute, repeated bouts of exercise by not having the ability to perform or recovery sufficiently to exercise on subsequent days. Conversely, trained individuals may be able to recover more quickly due to their enhanced metabolic systems. D-Ribose (DR) has been shown to enhance the recovery in ATP; however, it is not known if recovery and performance can be benefitted with DR ingestion. Therefore, this study was designed to determine what influence DR might have on muscular performance, recovery, and metabolism during and following a multi-day exercise regimen. Methods: The study was a double blind, crossover study in 26 healthy subjects compared 10 g/day of DR to 10 g/day of dextrose (DEX, control). All subjects completed 2 days of loading with either DR or DEX, followed by 3 additional days of supplementation and during these 3 days of supplementation, each subject underwent 60 min of high intensity interval exercise in separate daily sessions, which involved cycling (8 min of exercise at 60% and 2 min at 80% VO max), followed by a 2 min power output (PO) test. Subjects were divided into two groups based on peak VO results, lower VO (LVO ) and higher peak VO (HVO ). Results: Mean and peak PO increased significantly from day 1 to day 3 for the DR trial compared to DEX in the LVO group. Rate of perceived exertion (RPE) and creatine kinase (CK) were significantly lower for DR than DEX in the LVO group. No differences in PO, RPE, heart rate, CK, blood urea nitrogen, or glucose were found between either supplement for the HVO group. Conclusion: DR supplementation in the lower VO max group resulted in maintenance in exercise performance, as well as lower levels of RPE and CK. Unlike no observed benefits with DEX supplementation. |
[Mh] Termos MeSH primário: |
Trifosfato de Adenosina/metabolismo Limiar Anaeróbio/efeitos dos fármacos Desempenho Atlético/fisiologia Suplementos Nutricionais Músculo Esquelético/efeitos dos fármacos Músculo Esquelético/metabolismo Aptidão Física/fisiologia Ribose/farmacologia
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[Mh] Termos MeSH secundário: |
Adulto Limiar Anaeróbio/fisiologia Estudos Cross-Over Método Duplo-Cego Metabolismo Energético/efeitos dos fármacos Feminino Seres Humanos Masculino Fenômenos Fisiológicos da Nutrição Esportiva
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[Pt] Tipo de publicação: | CLINICAL TRIAL; COMPARATIVE STUDY; JOURNAL ARTICLE |
[Nm] Nome de substância:
| 681HV46001 (Ribose); 8L70Q75FXE (Adenosine Triphosphate) |
[Em] Mês de entrada: | 1803 |
[Cu] Atualização por classe: | 180308 |
[Lr] Data última revisão:
| 180308 |
[Sb] Subgrupo de revista: | IM |
[Da] Data de entrada para processamento: | 180104 |
[St] Status: | MEDLINE |
[do] DOI: | 10.1186/s12970-017-0205-8 |
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