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[PMID]:29370201
[Au] Autor:Fang H; Jiang D; Yang T; Fang L; Yang J; Li W; Zhao J
[Ad] Endereço:Department of Military Logistics, Army Logistics University, Chongqing, China.
[Ti] Título:Network evolution model for supply chain with manufactures as the core.
[So] Source:PLoS One;13(1):e0191180, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Building evolution model of supply chain networks could be helpful to understand its development law. However, specific characteristics and attributes of real supply chains are often neglected in existing evolution models. This work proposes a new evolution model of supply chain with manufactures as the core, based on external market demand and internal competition-cooperation. The evolution model assumes the external market environment is relatively stable, considers several factors, including specific topology of supply chain, external market demand, ecological growth and flow conservation. The simulation results suggest that the networks evolved by our model have similar structures as real supply chains. Meanwhile, the influences of external market demand and internal competition-cooperation to network evolution are analyzed. Additionally, 38 benchmark data sets are applied to validate the rationality of our evolution model, in which, nine manufacturing supply chains match the features of the networks constructed by our model.
[Mh] Termos MeSH primário: Equipamentos e Provisões
Indústria Manufatureira
[Mh] Termos MeSH secundário: Comércio
Simulação por Computador
Marketing
Modelos Teóricos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180226
[Lr] Data última revisão:
180226
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180126
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0191180


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[PMID]:29365306
[Au] Autor:Martin EG; Schackman BR
[Ad] Endereço:From the Rockefeller Institute of Government and the Department of Public Administration and Policy, University at Albany, State University of New York, Albany (E.G.M.); and the Department of Healthcare Policy and Administration, Weill Cornell Medical College, New York (B.R.S.).
[Ti] Título:Treating and Preventing HIV with Generic Drugs - Barriers in the United States.
[So] Source:N Engl J Med;378(4):316-319, 2018 Jan 25.
[Is] ISSN:1533-4406
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Antirretrovirais/uso terapêutico
Custos de Medicamentos
Medicamentos Genéricos/uso terapêutico
Infecções por HIV/tratamento farmacológico
[Mh] Termos MeSH secundário: Antirretrovirais/economia
Redução de Custos
Combinação de Medicamentos
Quimioterapia Combinada
Medicamentos Genéricos/economia
Infecções por HIV/prevenção & controle
Seres Humanos
Seguro de Serviços Farmacêuticos/economia
Legislação de Medicamentos
Marketing
Estados Unidos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Retroviral Agents); 0 (Drug Combinations); 0 (Drugs, Generic)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180208
[Lr] Data última revisão:
180208
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180125
[St] Status:MEDLINE
[do] DOI:10.1056/NEJMp1710914


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[PMID]:28471245
[Au] Autor:Peer N
[Ad] Endereço:a Non-communicable Diseases Research Unit, South African Medical Research Council , Durban , South Africa.
[Ti] Título:There has been little progress in implementing comprehensive alcohol control strategies in Africa.
[So] Source:Am J Drug Alcohol Abuse;43(6):631-635, 2017 Nov.
[Is] ISSN:1097-9891
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Alcohol is the most common substance of addiction and a threat not only to health but also to sustainable human development. Consequently, at least a 10% relative reduction in the harmful use of alcohol has been advocated by the World Health Organization (WHO). This perspective describes alcohol use in Africa, strategies to reduce harmful alcohol use, and the ability of African countries to meet this target. Although alcohol consumption in Africa was intermediate compared to other world regions, the total alcohol per capita among alcohol consumers was the second highest (19.5 liters); 19% of Sub-Saharan African men could be classified as binge drinkers. The alcohol industry is the key driver behind the uptake of alcohol use and misuse. The most cost-effective ways to reduce alcohol-related harm is to make alcohol less available and more expensive and to prohibit alcohol advertising. Most African countries have alcohol excise taxes, but these are not adjusted for inflation, meaning that the effectiveness of these taxes will likely decrease with time, leading to greater affordability. The majority of African countries do not have legally binding regulations for alcohol marketing. Alcohol misuse in Africa is not being addressed at a time when available strategies can efficiently and cost-effectively control alcohol-related harm.
[Mh] Termos MeSH primário: Consumo de Bebidas Alcoólicas/epidemiologia
Redução do Dano
[Mh] Termos MeSH secundário: Adolescente
África/epidemiologia
Consumo de Bebidas Alcoólicas/economia
Feminino
Seres Humanos
Masculino
Marketing/legislação & jurisprudência
Impostos
Consumo de Álcool por Menores/estatística & dados numéricos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180205
[Lr] Data última revisão:
180205
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170505
[St] Status:MEDLINE
[do] DOI:10.1080/00952990.2017.1316986


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[PMID]:28929484
[Au] Autor:Zeitoun JD; Baron G; Vivot A; Atal I; Downing NS; Ross JS; Ravaud P
[Ad] Endereço:Centre d'Épidémiologie Clinique, Hôpital Hôtel Dieu, Assistance Publique-Hôpitaux de Paris, Paris, France.
[Ti] Título:Post-marketing research and its outcome for novel anticancer agents approved by both the FDA and EMA between 2005 and 2010: A cross-sectional study.
[So] Source:Int J Cancer;142(2):414-423, 2018 Jan 15.
[Is] ISSN:1097-0215
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Post-marketing research in oncology has rarely been described. We aimed to characterize post-marketing trials for a consistent set of anticancer agents over a long period. We performed a cross-sectional analysis of post-marketing trials registered at ClinicalTrials.gov through September 2014 for novel anticancer agents approved by both the US Food and Drug Administration and the European Medicines Agency between 2005 and 2010. All relevant post-marketing trials were classified according to indication, primary outcome, starting date, sponsors, and planned enrollment. Supplemental indications were retrieved from regulatory documents and publication rate was assessed by two different methods. Ten novel anticancer agents were eligible: five were indicated for hematologic malignancies and the remaining five for solid cancers (three for kidney cancer). We identified 2,345 post-marketing trials; 1,362 (58.1%) targeted an indication other than the originally approved one. We observed extreme variations among drugs in both number of post-marketing trials (range 8-530) and overall population to be enrolled per trial (1-8,381). Post-marketing trials assessed almost all types of cancers, the three most frequently studied cancers being leukemia, kidney cancer and myeloma. In all, 6.6% of post-marketing trials had a clinical endpoint as a primary outcome, and 35.9% and 54.1% had a safety or surrogate endpoint, respectively, as a primary outcome. Nine drugs obtained approval for supplemental indications. The publication rate at 10 years was 12.3 to 26.1% depending on the analysis method. In conclusion, we found that post-marketing research in oncology is highly heterogeneous and the publication rate of launched trials is low.
[Mh] Termos MeSH primário: Antineoplásicos/uso terapêutico
Ensaios Clínicos como Assunto/normas
Aprovação de Drogas/legislação & jurisprudência
Órgãos Governamentais/legislação & jurisprudência
Marketing
Neoplasias/tratamento farmacológico
Projetos de Pesquisa
[Mh] Termos MeSH secundário: Estudos Transversais
Revisão de Uso de Medicamentos
União Europeia
Seres Humanos
Avaliação de Resultados (Cuidados de Saúde)
Estados Unidos
United States Food and Drug Administration
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antineoplastic Agents)
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171214
[Lr] Data última revisão:
171214
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170921
[St] Status:MEDLINE
[do] DOI:10.1002/ijc.31061


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[PMID]:28465309
[Au] Autor:Greenway T; Ross JS
[Ad] Endereço:Yale University School of Medicine, New Haven, Connecticut, USA.
[Ti] Título:US drug marketing: how does promotion correspond with health value?
[So] Source:BMJ;357:j1855, 2017 05 02.
[Is] ISSN:1756-1833
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Indústria Farmacêutica/economia
Prescrições de Medicamentos/normas
Promoção da Saúde/economia
Marketing/economia
Medicamentos sob Prescrição/normas
[Mh] Termos MeSH secundário: Seres Humanos
Motivação
Padrões de Prática Médica/economia
Estados Unidos
[Pt] Tipo de publicação:JOURNAL ARTICLE; VIDEO-AUDIO MEDIA
[Nm] Nome de substância:
0 (Prescription Drugs)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171128
[Lr] Data última revisão:
171128
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170504
[St] Status:MEDLINE
[do] DOI:10.1136/bmj.j1855


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[PMID]:29093052
[Au] Autor:Lapierre MA; Fleming-Milici F; Rozendaal E; McAlister AR; Castonguay J
[Ad] Endereço:Department of Communication, University of Arizona, Tucson, Arizona; mlapierre@email.arizona.edu.
[Ti] Título:The Effect of Advertising on Children and Adolescents.
[So] Source:Pediatrics;140(Suppl 2):S152-S156, 2017 Nov.
[Is] ISSN:1098-4275
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:In ∼100 years, marketing to children went from a severely frowned upon practice to an integral part of growing up as companies came to realize that investing in marketing to children and adolescents provides excellent immediate and future dividends. Each year, enormous sums of money are spent to reach this valuable audience because children and adolescents spend billions on their own purchases, influence family decisions about what to buy, and promise a potential lifetime of brand loyalty. The channels to reach youth have grown, and marketers are increasingly using them, often blurring the distinction between entertainment and advertising. Because advertising to children and adolescents has become ubiquitous, researchers who study its influence raise significant concerns about the practice, especially as it relates to dietary behavior, family conflict, marketer tactics, and children's potential vulnerability as an audience. In this review by the Workgroup on Marketing and Advertising, we highlight the state of the research in this area and suggest that more research needs to be conducted on understanding the following: the effects of advertising exposure, how psychological development affects children's responses to marketing, the problems associated with advertising in newer media, and how researchers, parents, and practitioners might be able to mitigate the most deleterious advertising effects. We then present avenues of future research along with recommendations for key stakeholders.
[Mh] Termos MeSH primário: Publicidade como Assunto/métodos
Comportamento Infantil/psicologia
Marketing/métodos
Meios de Comunicação de Massa
[Mh] Termos MeSH secundário: Adolescente
Publicidade como Assunto/economia
Bebidas Alcoólicas/economia
Criança
Tomada de Decisões
Seres Humanos
Marketing/economia
Meios de Comunicação de Massa/economia
Tabaco
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171113
[Lr] Data última revisão:
171113
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171103
[St] Status:MEDLINE
[do] DOI:10.1542/peds.2016-1758V


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[PMID]:29049522
[Au] Autor:Kolodny A; Frieden TR
[Ad] Endereço:Heller School for Social Policy and Management, Brandeis University, Waltham, Massachusetts.
[Ti] Título:Ten Steps the Federal Government Should Take Now to Reverse the Opioid Addiction Epidemic.
[So] Source:JAMA;318(16):1537-1538, 2017 10 24.
[Is] ISSN:1538-3598
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Analgésicos Opioides/uso terapêutico
Epidemias/prevenção & controle
Redução do Dano
Transtornos Relacionados ao Uso de Opioides/prevenção & controle
[Mh] Termos MeSH secundário: Rotulagem de Medicamentos/legislação & jurisprudência
Overdose de Drogas/diagnóstico
Governo Federal
Seres Humanos
Cobertura do Seguro
Seguro de Serviços Farmacêuticos
Marketing
Transtornos Relacionados ao Uso de Opioides/tratamento farmacológico
Transtornos Relacionados ao Uso de Opioides/epidemiologia
Estados Unidos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Analgesics, Opioid)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171101
[Lr] Data última revisão:
171101
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171020
[St] Status:MEDLINE
[do] DOI:10.1001/jama.2017.14567


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[PMID]:29048960
[Au] Autor:Mackey TK; Kalyanam J; Katsuki T; Lanckriet G
[Ad] Endereço:Tim K. Mackey is with the Department of Anesthesiology and Department of Medicine, University of California, San Diego, and the Global Health Policy Institute, San Diego. Janani Kalyanam is with the Global Health Policy Institute and the Department of Electrical and Computer Engineering, University
[Ti] Título:Twitter-Based Detection of Illegal Online Sale of Prescription Opioid.
[So] Source:Am J Public Health;107(12):1910-1915, 2017 Dec.
[Is] ISSN:1541-0048
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVES: To deploy a methodology accurately identifying tweets marketing the illegal online sale of controlled substances. METHODS: We first collected tweets from the Twitter public application program interface stream filtered for prescription opioid keywords. We then used unsupervised machine learning (specifically, topic modeling) to identify topics associated with illegal online marketing and sales. Finally, we conducted Web forensic analyses to characterize different types of online vendors. We analyzed 619 937 tweets containing the keywords codeine, Percocet, fentanyl, Vicodin, Oxycontin, oxycodone, and hydrocodone over a 5-month period from June to November 2015. RESULTS: A total of 1778 tweets (< 1%) were identified as marketing the sale of controlled substances online; 90% had imbedded hyperlinks, but only 46 were "live" at the time of the evaluation. Seven distinct URLs linked to Web sites marketing or illegally selling controlled substances online. CONCLUSIONS: Our methodology can identify illegal online sale of prescription opioids from large volumes of tweets. Our results indicate that controlled substances are trafficked online via different strategies and vendors. Public Health Implications. Our methodology can be used to identify illegal online sellers in criminal violation of the Ryan Haight Online Pharmacy Consumer Protection Act.
[Mh] Termos MeSH primário: Analgésicos Opioides
Crime
Disponibilidade de Medicamentos Via Internet
Uso Indevido de Medicamentos sob Prescrição
Mídias Sociais/utilização
[Mh] Termos MeSH secundário: Seres Humanos
Marketing
Saúde Pública
Aprendizado de Máquina não Supervisionado
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Analgesics, Opioid)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171113
[Lr] Data última revisão:
171113
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171020
[St] Status:MEDLINE
[do] DOI:10.2105/AJPH.2017.303994


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Almeida, Liz Maria de
Texto completo SciELO Brasil
Texto completo SciELO Saúde Pública
[PMID]:28954059
[Au] Autor:Almeida LM; Silva RPD; Santos ATCD; Andrade JD; Suarez MC
[Ad] Endereço:Instituto Nacional de Câncer José Alencar Gomes da Silva, Rio de Janeiro, Brasil.
[Ti] Título:Mists, vapors and other illusory volatilities of electronic cigarettes.
[Ti] Título:Névoas, vapores e outras volatilidades ilusórias dos cigarros eletrônicos..
[So] Source:Cad Saude Publica;33Suppl 3(Suppl 3):e00139615, 2017 Sep 21.
[Is] ISSN:1678-4464
[Cp] País de publicação:Brazil
[La] Idioma:por; eng
[Ab] Resumo:In this article, we analyze the discourse of electronic cigarette suppliers directed at convincing potential users (smokers, former smokers or never smokers) to acquire and use the new product. This is a qualitative, descriptive and exploratory study on sellers' discourse found in eight on-line sales websites which, between 2011 and 2013, had the highest search frequencies. The websites were identified through Google Trends based on the number of accesses and search frequencies related to electronic cigarettes. Our methodological reference was dialectical-hermeneutics. We categorized the empirical material within the "understanding/interpretation" scheme within four broad meanings: appropriation of the anti-smoking discourse; comparison between conventional and electronic cigarettes; appeal to the trustworthiness of science and projection of e-cigarettes' image. The analysis of these meanings configured the argumentative elements of the marketing discourse used by electronic cigarette makers and suppliers.
[Mh] Termos MeSH primário: Sistemas Eletrônicos de Liberação de Nicotina
Marketing
Tabagismo
[Mh] Termos MeSH secundário: Brasil
Sistemas Eletrônicos de Liberação de Nicotina/economia
Seres Humanos
Fumar
Indústria do Tabaco
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170928
[St] Status:MEDLINE


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[PMID]:28934269
[Au] Autor:Jones SC; Hall S; Kypri K
[Ad] Endereço:Centre for Health and Social Research, Australian Catholic University, Melbourne, Victoria, Australia.
[Ti] Título:Should I drink responsibly, safely or properly? Confusing messages about reducing alcohol-related harm.
[So] Source:PLoS One;12(9):e0184705, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:'Responsible drinking' campaigns emerged in the early 1970s as a means of addressing hazardous drinking and its related consequences. While these were initially the product of public health agencies and health-related NGOs, they are increasingly being developed and disseminated by the alcohol industry. There is considerable debate as to whether industry-generated campaigns are designed to reduce hazardous drinking and related problems (as argued by their developers) or are designed to avoid government regulation or even to increase sales. The aim of the present study was to explore the way that recent industry-developed responsible drinking campaigns are perceived and interpreted by the general public. That is, do they promote low-risk drinking, promote risky drinking, or just muddy the waters. Two sub-studies were conducted. The first, a mall intercept study with 180 adults in two Australian shopping districts, explored participants' understanding of slogans/taglines. The second, an online survey with 480 Australian adults, explored understandings and interpretations of television/online commercials. The results of the two studies revealed diversity in participants' interpretation of the 'responsible drinking' advertisements. Terminology utilised in industry-developed advertisements was found to be ambiguous; for example, what age group was being referred to in the tagline 'Kids and alcohol don't mix', and whether 'Drink Properly' meant not drinking to excess or drinking in a way that made you look more sophisticated. In Study Two, the government-developed campaign ('Know when to say when') was clearly interpreted as warning against risky consumption of alcohol; whereas the industry-developed campaigns ('How to drink properly', 'Kids absorb your drinking', 'Friends are waiting') were interpreted to have a range of different meanings, including some seemingly unrelated to alcohol. These findings are consistent with the literature evaluating anti-smoking campaigns developed by the tobacco industry, and previous research showing that industry communications serve to soften public opinion and create the impression of a 'socially responsible' industry but are likely to be less effective than initiatives focused on the availability and promotion of alcohol.
[Mh] Termos MeSH primário: Consumo de Bebidas Alcoólicas
Comunicação
Promoção da Saúde
[Mh] Termos MeSH secundário: Adolescente
Adulto
Austrália
Compreensão
Feminino
Governo
Redução do Dano
Conhecimentos, Atitudes e Prática em Saúde
Promoção da Saúde/métodos
Seres Humanos
Indústrias
Internet
Masculino
Marketing
Meia-Idade
Assunção de Riscos
Inquéritos e Questionários
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171024
[Lr] Data última revisão:
171024
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170922
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0184705



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