Base de dados : MEDLINE
Pesquisa : J01.637.597 [Categoria DeCS]
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[PMID]:29406025
[Au] Autor:Robbins Z; Bodnar W; Zhang Z; Gold A; Nylander-French LA
[Ad] Endereço:Department of Environmental Sciences and Engineering, Gillings School of Global Public Health, The University of North Carolina at Chapel Hill, NC 27599, USA.
[Ti] Título:Trisaminohexyl isocyanurate, a urinary biomarker of HDI isocyanurate exposure.
[So] Source:J Chromatogr B Analyt Technol Biomed Life Sci;1076:117-129, 2018 Feb 15.
[Is] ISSN:1873-376X
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Biological monitoring of occupational exposure to 1,6-hexamethylene diisocyanate (HDI)-containing spray-paints is limited to analysis of metabolites of HDI monomer although polymeric HDI isocyanurate constitutes the predominant inhalation and skin exposure for workers in the automotive paint industry. A novel method using nanoflow ultra-performance liquid chromatography coupled to nano-electrospray ionization tandem mass spectrometry (nano-UPLC-ESI-MS/MS) was developed to quantify trisaminohexyl isocyanurate (TAHI), a hydrolysis product of HDI isocyanurate, in the urine of spray-painters. Analytical and internal standards were synthesized in-house and weighted linear regression calibration curves were generated using spiked control urine from non-exposed persons (0.06-7.98 µg/L; N = 13; w = x ; r = 0.998). Urine samples collected from 15 exposed workers (N = 111) were subjected to acid hydrolysis and extracted with dichloromethane, then derivatized with acetic anhydride. The derivatized product, trisacetamidohexyl isocyanurate (TAAHI), was analyzed using nano-UPLC-ESI-MS/MS. The protocol was sensitive and specific for analysis of TAHI in the urine of exposed workers with a method detection limit at 0.03 µg/L. TAHI was detected in 33 of 111 urine samples and in 11 of 15 workers. This biomarker for HDI isocyanurate is critical to determine the relative potency and dose-relationships between the monomer and oligomer exposure on the development of diisocyanate induced health effects in future studies.
[Mh] Termos MeSH primário: Isocianatos/toxicidade
Exposição Ocupacional/análise
Triazinas/urina
[Mh] Termos MeSH secundário: Biomarcadores/química
Biomarcadores/urina
Cromatografia Líquida de Alta Pressão
Seres Humanos
Masculino
Nanotecnologia
Pintura
Espectrometria de Massas em Tandem
Triazinas/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Biomarkers); 0 (Isocyanates); 0 (Triazines); 0 (trisaminohexyl isocyanurate); 0I70A3I1UF (1,6-hexamethylene diisocyanate)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180307
[Lr] Data última revisão:
180307
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180207
[St] Status:MEDLINE


  2 / 3037 MEDLINE  
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[PMID]:28449753
[Au] Autor:Brignardello-Petersen R
[Ti] Título:Regular oral health education is effective in reducing caries incidence whereas fluoride varnish seems to have no added benefit.
[So] Source:J Am Dent Assoc;148(5):e49, 2017 05.
[Is] ISSN:1943-4723
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Cárie Dentária
Fluoretos
[Mh] Termos MeSH secundário: Cariostáticos
Fluoretos Tópicos
Educação em Saúde Bucal
Seres Humanos
Incidência
Pintura
[Pt] Tipo de publicação:REVIEW; COMMENT
[Nm] Nome de substância:
0 (Cariostatic Agents); 0 (Fluorides, Topical); Q80VPU408O (Fluorides)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180305
[Lr] Data última revisão:
180305
[Sb] Subgrupo de revista:D; IM
[Da] Data de entrada para processamento:170429
[St] Status:MEDLINE


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[PMID]:29217805
[Au] Autor:Garg N; Gupta N; Shah D; Gupta P
[Ad] Endereço:Departments of Pediatrics and *Radiology, University College of Medical Sciences (University of Delhi) and GTB Hospital, Dilshad Garden, Delhi, India. Correspondence to: Dr Dheeraj Shah, Professor, Department of Pediatrics, University College of Medical Sciences and GTB Hospital, Dilshad Garden, Delhi 110 095, India. shahdheeraj@hotmail.com.
[Ti] Título:Paint in the Pipe: An Unusual Foreign Body.
[So] Source:Indian Pediatr;54(11):963-965, 2017 Nov 15.
[Is] ISSN:0974-7559
[Cp] País de publicação:India
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Foreign bodies in the airway can be a diagnostic and therapeutic challenge. CASE CHARACTERISTICS: 30-month-old girl with complaints of noisy and fast breathing following fall over a pile of sand. Sand was suctioned out by direct bronchoscopy. The child improved initially but condition worsened in next four days with marked stridor and wheeze. OBSERVATION: Imaging revealed elongated sharp radiodense opacity in the cervical region, suggestive of foreign body. At repeat bronchoscopy, paint material was removed from the airway, leading to recovery. MESSAGE: Paint material mixed in the sand can adhere to the walls of the airway, and cause persistent symptoms of obstruction.
[Mh] Termos MeSH primário: Corpos Estranhos
Pintura/efeitos adversos
Sons Respiratórios/etiologia
Traqueia
[Mh] Termos MeSH secundário: Broncoscopia
Pré-Escolar
Feminino
Corpos Estranhos/diagnóstico por imagem
Corpos Estranhos/patologia
Corpos Estranhos/fisiopatologia
Seres Humanos
Tomografia Computadorizada por Raios X
Traqueia/diagnóstico por imagem
Traqueia/patologia
Traqueia/fisiopatologia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180105
[Lr] Data última revisão:
180105
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171209
[St] Status:MEDLINE


  4 / 3037 MEDLINE  
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[PMID]:28780566
[Au] Autor:Järvholm B; Burdorf A
[Ad] Endereço:Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.
[Ti] Título:Effect of reduced use of organic solvents on disability pension in painters.
[So] Source:Occup Environ Med;74(11):827-829, 2017 Nov.
[Is] ISSN:1470-7926
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To investigate whether the decreased use of paints based on organic solvents has caused a decreased risk for neuropsychiatric disorders in painters by studying their incidence in disability pensions. METHODS: The incidence of disability pension in Swedish painters who had participated in health examinations between 1971 and 1993 was studied through linkage with Swedish registers of disability pension over 1971-2010 and compared with the incidence in other construction workers as woodworkers, concrete workers and platers. When phasing out began in the 1970s, about 40% of paints were based on organic solvents and it had decreased to 4% in 1990s. The analysis was adjusted for age, time period, body mass index and smoking. RESULTS: The painters (n=23 065) had an increased risk of disability pension due to neurological diagnosis (n=285, relative risk (RR) 1.92, 95% CI 1.67 to 2.20) and psychiatric diagnosis (n=632, RR=1.61, 95 % CI 1.42 to 1.82). For neurological disorders there was a time trend with a continuously decreasing risk from 1980 onwards, but there was no such trend for psychiatric disorders. CONCLUSIONS: High exposure to organic solvents increased the risk for disability pension in neurological disorders, and the risk decreased when the use of organic solvents decreased. The painters also had an increased risk of disability pension due to psychiatric disorders, but the causes have to be further investigated.
[Mh] Termos MeSH primário: Indústria da Construção
Pessoas com Deficiência
Doenças do Sistema Nervoso/prevenção & controle
Doenças Profissionais/prevenção & controle
Exposição Ocupacional/efeitos adversos
Pensões
Solventes/efeitos adversos
[Mh] Termos MeSH secundário: Adulto
Indústria da Construção/tendências
Seres Humanos
Incidência
Masculino
Transtornos Mentais/induzido quimicamente
Meia-Idade
Doenças do Sistema Nervoso/induzido quimicamente
Doenças Profissionais/induzido quimicamente
Ocupações
Compostos Orgânicos/efeitos adversos
Pintura
Medição de Risco
Fatores de Risco
Suécia
Indenização aos Trabalhadores
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Organic Chemicals); 0 (Solvents)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171102
[Lr] Data última revisão:
171102
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170807
[St] Status:MEDLINE
[do] DOI:10.1136/oemed-2017-104421


  5 / 3037 MEDLINE  
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[PMID]:28661802
[Au] Autor:Braun PA; Widmer-Racich K; Sevick C; Starzyk EJ; Mauritson K; Hambidge SJ
[Ad] Endereço:Patricia A. Braun, Katina Widmer-Racich, and Carter Sevick are with the Adult and Child Consortium for Health Outcomes Research and Delivery Science, University of Colorado Anschutz School of Medicine, Aurora. Erin J. Starzyk and Katya Mauritson are with the Colorado Department of Public Health and
[Ti] Título:Effectiveness on Early Childhood Caries of an Oral Health Promotion Program for Medical Providers.
[So] Source:Am J Public Health;107(S1):S97-S103, 2017 May.
[Is] ISSN:1541-0048
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVES: To assess an oral health promotion (OHP) intervention for medical providers' impact on early childhood caries (ECC). METHODS: We implemented a quasiexperimental OHP intervention in 8 federally qualified health centers that trained medical providers on ECC risk assessment, oral examination and instruction, dental referral, and fluoride varnish applications (FVAs). We measured OHP delivery by FVA count at medical visits. We measured the intervention's impact on ECC in 3 unique cohorts of children aged 3 to 4 years in 2009 (preintervention; n = 202), 2011 (midintervention; n = 420), and 2015 (≥ 4 FVAs; n = 153). We compared numbers of decayed, missing, and filled tooth surfaces using adjusted zero-inflated negative binomial models. RESULTS: Across 3 unique cohorts, the FVA mean (range) count was 0.0 (0), 1.1 (0-7), and 4.5 (4-7) in 2009, 2011, and 2015, respectively. In adjusted zero-inflated negative binomial models analyses, children in the 2015 cohort had significantly fewer decayed, missing, and filled tooth surfaces than did children in previous cohorts. CONCLUSIONS: An OHP intervention targeting medical providers reduced ECC when children received 4 or more FVAs at a medical visit by age 3 years.
[Mh] Termos MeSH primário: Cárie Dentária/prevenção & controle
Pessoal de Saúde/educação
Promoção da Saúde
Saúde Bucal
[Mh] Termos MeSH secundário: Pré-Escolar
Odontólogos
Diagnóstico Bucal/métodos
Fluoretos
Seres Humanos
Pintura
Fosfatos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Phosphates); 15181-43-8 (fluorophosphate); Q80VPU408O (Fluorides)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170714
[Lr] Data última revisão:
170714
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170630
[St] Status:MEDLINE
[do] DOI:10.2105/AJPH.2017.303817


  6 / 3037 MEDLINE  
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[PMID]:28604166
[Au] Autor:Tribou M; Swain G
[Ad] Endereço:a Department of Ocean Engineering and Sciences , Florida Institute of Technology , Melbourne , FL , USA.
[Ti] Título:The effects of grooming on a copper ablative coating: a six year study.
[So] Source:Biofouling;33(6):494-504, 2017 Jul.
[Is] ISSN:1029-2454
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:More than 90% of US Navy Ships are coated with copper ablative paint. These ships may spend long periods of time pier-side, which makes them vulnerable to fouling. Hull grooming has been proposed as a means of maintaining the coatings in an operational condition. This study investigated the effect of grooming on a copper ablative coating exposed statically for six years. Grooming was performed weekly or monthly with controls left ungroomed. The fouling community was visually assessed, dry film thickness measurements were taken to monitor coating loss, and the copper leaching rates were measured. It was found that weekly and monthly groomed surfaces reduced fouling, and the ungroomed surfaces became fully fouled. Coating loss was similar for weekly, monthly and ungroomed surfaces. The results suggest that grooming is a viable method for maintaining copper ablative coatings in a fouling-free condition without adverse increases in the total copper output.
[Mh] Termos MeSH primário: Biofilmes/crescimento & desenvolvimento
Incrustação Biológica/prevenção & controle
Cobre/química
Pintura
Navios
[Mh] Termos MeSH secundário: Modelos Teóricos
Propriedades de Superfície
Fatores de Tempo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
789U1901C5 (Copper)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171003
[Lr] Data última revisão:
171003
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170613
[St] Status:MEDLINE
[do] DOI:10.1080/08927014.2017.1328596


  7 / 3037 MEDLINE  
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[PMID]:28528312
[Au] Autor:Falkenberg LJ; Wrange AL; Kinnby A; Havenhand JN; Lockyer A; Styan CA
[Ad] Endereço:UCL Australia, University College London, 220 Victoria Square, Adelaide, SA, 5000, Australia. Electronic address: laura.falkenberg@niva.no.
[Ti] Título:Low sensitivity of reproductive life-stages in the Pacific oyster (Crassostrea gigas) to abamectin.
[So] Source:Chemosphere;182:665-671, 2017 Sep.
[Is] ISSN:1879-1298
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Hard surfaces submerged in the marine environment often become colonised by macro-organisms unless the surfaces have some form of biofouling protection. While protective paints that contain tributyltin or copper work well to prevent biofouling, release of these materials into the environment has been shown to have wider negative impacts. Consequently, new low-release antifouling paints are being developed with alternative active ingredients, such as avermectins, yet little is known about their potential effects on non-target organisms in marine environments. Here we investigated the toxicity of a key avermectin, specifically abamectin, on several aspects of reproduction (sperm motility, fertilisation success, early larval development) in the Pacific oyster, Crassostrea gigas. Oyster reproduction was generally insensitive to the low concentrations of abamectin, although greater concentrations of abamectin did negatively affect all three endpoints - LOECs were 1000 µg l , 500 µg l , and 100 µg l abamectin for sperm motility, fertilisation success, and larval development, respectively. A similar pattern was found in the EC s of the three endpoints (mean ± SE) 934 ± 59 µg l , 1076.26 ± 725.61 µg l , and 140 ± 78 µg l abamectin (sperm motility, fertilisation success, and larval development, respectively). Together, these results clearly indicate that of the three endpoints considered, larval development was more sensitive to abamectin (lower LOEC, EC ) than fertilisation success and sperm motility. Although more data are needed from a wider range of marine species and environments to fully assess potential toxicity effects on non-target organisms, our results highlight the potential utility of abamectin in low-release antifouling paints.
[Mh] Termos MeSH primário: Ivermectina/análogos & derivados
Reprodução/efeitos dos fármacos
[Mh] Termos MeSH secundário: Animais
Crassostrea
Fertilização/efeitos dos fármacos
Ivermectina/farmacologia
Larva/efeitos dos fármacos
Larva/crescimento & desenvolvimento
Estágios do Ciclo de Vida/efeitos dos fármacos
Pintura/efeitos adversos
Poluentes Químicos da Água/farmacologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Water Pollutants, Chemical); 5U8924T11H (abamectin); 70288-86-7 (Ivermectin); 73989-17-0 (avermectin)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170922
[Lr] Data última revisão:
170922
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170522
[St] Status:MEDLINE


  8 / 3037 MEDLINE  
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[PMID]:28506499
[Au] Autor:Chung SWC; Wu AHT
[Ad] Endereço:Food Research Laboratory, Centre for Food Safety, Food and Environmental Hygiene Department, 4/F Public Health Laboratory Centre, 382 Nam Cheong Street, Hong Kong. Electronic address: swcchung@fehd.gov.hk.
[Ti] Título:Determination of butyltins, phenyltins and octyltins in foods with preservation of their moieties: A critical review on analytical methods.
[So] Source:J Chromatogr A;1505:18-34, 2017 Jul 07.
[Is] ISSN:1873-3778
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Tributyltin and triphenyltin have been extensively applied in anti-fouling paints since the 1960s. Hence, organotin compounds (OTCs), especially butyltins and phenyltins, in seafood has been of concern for decades. Even though the "International Convention on the Control of Harmful Anti-Fouling Systems on Ships, 2001" entered into force internationally in 2008 and prohibited the use of OTCs in anti-fouling paints used on ships, the analysis of OTCs in seafood was not commonly included in routine monitoring programmes. Besides, species of triphenyltin, including triphenyltin hydroxide and acetate, have been used as pesticides and may accumulate in food. Moreover, the European Food Safety Agency established a group tolerable daily intake for tributyltin, dibutyltin, triphenyltin and dioctyltin in 2004 as they exert their immunotoxic effects by similar mode of action and potency. Therefore, suitable methods are needed to analyze butyl-, phenyl- and octyl-tins simultaneously in food without affecting their moieties. This review aims to provide background information in this area.
[Mh] Termos MeSH primário: Técnicas de Química Analítica/métodos
Contaminação de Alimentos/análise
Compostos Orgânicos de Estanho/química
Poluentes Químicos da Água/química
[Mh] Termos MeSH secundário: Técnicas de Química Analítica/instrumentação
Estrutura Molecular
Pintura/análise
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Organotin Compounds); 0 (Water Pollutants, Chemical); 2406-68-0 (phenyltin)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171016
[Lr] Data última revisão:
171016
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170517
[St] Status:MEDLINE


  9 / 3037 MEDLINE  
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[PMID]:28477005
[Au] Autor:Tiwari N; Pandit R; Gaikwad S; Gade A; Rai M
[Ad] Endereço:Department of Biotechnology, SGB Amravati University, Amravati 444 602, Maharashtra, India.
[Ti] Título:Biosynthesis of zinc oxide nanoparticles by petals extract of L., its formulation as nail paint and evaluation of antifungal activity against fungi causing onychomycosis.
[So] Source:IET Nanobiotechnol;11(2):205-211, 2017 Mar.
[Is] ISSN:1751-8741
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The authors report the biological synthesis of zinc oxide nanoparticles (ZnO-NPs) from the petals extract of L. (rose). Its efficacy was evaluated against two dermatophytes: namely: and which cause onychomycosis. The activity of antibiotics against the tested dermatophytes was enhanced, when evaluated in combination with ZnO-NPs. The synthesised ZnO-NPs were preliminary detected by using ultraviolet UV visible spectroscopy, which showed specific absorbance. The ZnO-NPs were further characterised by nanoparticle tracking analysis (NTA), Fourier transform infrared spectroscopy (FTIR), transmission electron microscopy (TEM), X-ray diffraction and Zetasizer. Moreover, nanoparticles containing nail paint (nanopaint) was formulated and its antifungal activity was also assessed against and . ZnO-NPs and formulated nanopaint containing ZnO-NPs, both showed significant antifungal activity. The maximum activity was noted against and lesser against Minimum inhibitory concentration of ZnO-NPs was also determined against the dermatophytes causing onychomycosis infection. ZnO-NPs can be utilised as a potential antifungal agent for the treatment of onychomycosis after more experimental trials.
[Mh] Termos MeSH primário: Flores/química
Fungos/efeitos dos fármacos
Nanopartículas Metálicas/administração & dosagem
Onicomicose/microbiologia
Extratos Vegetais/química
Rosa/química
Óxido de Zinco/administração & dosagem
[Mh] Termos MeSH secundário: Antifúngicos
Produtos Biológicos
Sobrevivência Celular/efeitos dos fármacos
Cosméticos/administração & dosagem
Cosméticos/síntese química
Cosméticos/metabolismo
Relação Dose-Resposta a Droga
Composição de Medicamentos
Fungos/fisiologia
Seres Humanos
Teste de Materiais
Nanopartículas Metálicas/ultraestrutura
Unhas
Onicomicose/tratamento farmacológico
Onicomicose/patologia
Pintura
Tamanho da Partícula
Extratos Vegetais/administração & dosagem
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antifungal Agents); 0 (Biological Products); 0 (Cosmetics); 0 (Plant Extracts); SOI2LOH54Z (Zinc Oxide)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170507
[St] Status:MEDLINE
[do] DOI:10.1049/iet-nbt.2016.0003


  10 / 3037 MEDLINE  
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[PMID]:28379960
[Au] Autor:Lluveras-Tenorio A; Vinciguerra R; Galano E; Blaensdorf C; Emmerling E; Perla Colombini M; Birolo L; Bonaduce I
[Ad] Endereço:Dipartimento di Chimica e Chimica Industriale, Università di Pisa, Pisa, Italy.
[Ti] Título:GC/MS and proteomics to unravel the painting history of the lost Giant Buddhas of Bamiyan (Afghanistan).
[So] Source:PLoS One;12(4):e0172990, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:A chemical investigation of the organic paint binders of the Giant Buddhas of Bamiyan was performed using an analytical approach based on mass spectrometry, combining traditional gas chromatography/mass spectrometry protocols with advanced proteomics methodologies. The research was carried out on a selection of rescued fragments. The data revealed the use of egg proteins as the paint binders of the original layers, in accordance with the traditional use of this proteinaceous medium in antiquity, spanning from the Mediterranean basin to the Far East, and already in the Bronze Age. Egg tempera was thus known to artists of the region in the first centuries AD, probably also due to the position of the Bamiyan valley, which was connected to the Silk Road. Milk was found in the first historical overpaintings. A new proteomics approach was used, which was able to identify the source of the milk proteins present in the restoration layers, despite their age and degradation. In particular cow's and goat's milk were both found, in agreement with the documented presence of rich pastures in the Bamiyan valley when the historical restorations were carried out. Investigating the materials of the Giant Buddhas not only enabled us to obtain isolated data on these invaluable works of art, which are now lost, but contributes to understanding the big "puzzle" of our past and the development of our culture, by implementing and supporting written sources, stylistic and anthropological studies with molecular data.
[Mh] Termos MeSH primário: Pintura/análise
[Mh] Termos MeSH secundário: Afeganistão
Animais
Extremo Oriente
Cromatografia Gasosa-Espectrometria de Massas/métodos
Leite/química
Proteínas do Leite/química
Pinturas
Proteínas/química
Proteômica/métodos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Milk Proteins); 0 (Proteins)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170830
[Lr] Data última revisão:
170830
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170406
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0172990



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