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[PMID]:29370248
[Au] Autor:Zheng M; Li L; Peng H; Xiao J; Yang Y; Zhang Y; Zhao H
[Ad] Endereço:School of Science, Beijing University of Posts and Telecommunications, Beijing 100876, China.
[Ti] Título:Globally fixed-time synchronization of coupled neutral-type neural network with mixed time-varying delays.
[So] Source:PLoS One;13(1):e0191473, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:This paper mainly studies the globally fixed-time synchronization of a class of coupled neutral-type neural networks with mixed time-varying delays via discontinuous feedback controllers. Compared with the traditional neutral-type neural network model, the model in this paper is more general. A class of general discontinuous feedback controllers are designed. With the help of the definition of fixed-time synchronization, the upper right-hand derivative and a defined simple Lyapunov function, some easily verifiable and extensible synchronization criteria are derived to guarantee the fixed-time synchronization between the drive and response systems. Finally, two numerical simulations are given to verify the correctness of the results.
[Mh] Termos MeSH primário: Redes Neurais (Computação)
[Mh] Termos MeSH secundário: Simulação por Computador
Retroalimentação
Modelos Neurológicos
Dinâmica não Linear
Fatores de Tempo
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180302
[Lr] Data última revisão:
180302
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180126
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0191473


  2 / 27659 MEDLINE  
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[PMID]:29425015
[Ti] Título:When Doctors and Patients Troll Each Other, PHI Protection Suffers.
[So] Source:J AHIMA;87(8):64, 2016 08.
[Is] ISSN:1060-5487
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Registros de Saúde Pessoal
Relações Médico-Paciente
Privacidade
[Mh] Termos MeSH secundário: Retroalimentação
Health Insurance Portability and Accountability Act
Seres Humanos
Estados Unidos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180301
[Lr] Data última revisão:
180301
[Sb] Subgrupo de revista:H
[Da] Data de entrada para processamento:180210
[St] Status:MEDLINE


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[PMID]:29320600
[Au] Autor:Zaugg V; Korb-Savoldelli V; Durieux P; Sabatier B
[Ad] Endereço:Clinical Pharmacy Department, Georges Pompidou European Hospital, AP-HP, 20 rue Leblanc, Paris, France, 75015.
[Ti] Título:Providing physicians with feedback on medication adherence for people with chronic diseases taking long-term medication.
[So] Source:Cochrane Database Syst Rev;1:CD012042, 2018 Jan 10.
[Is] ISSN:1469-493X
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Poor medication adherence decreases treatment efficacy and worsens clinical outcomes, but average rates of adherence to long-term pharmacological treatments for chronic illnesses are only about 50%. Interventions for improving medication adherence largely focus on patients rather than on physicians; however, the strategies shown to be effective are complex and difficult to implement in clinical practice. There is a need for new care models addressing the problem of medication adherence, integrating this problem into the patient care process. Physicians tend to overestimate how well patients take their medication as prescribed. This can lead to missed opportunities to change medications, solve adverse effects, or propose the use of reminders in order to improve patients' adherence. Thus, providing physicians with feedback on medication adherence has the potential to prompt changes that improve their patients' adherence to prescribed medications. OBJECTIVES: To assess the effects of providing physicians with feedback about their patients' medication adherence for improving adherence. We also assessed the effects of the intervention on patient outcomes, health resource use, and processes of care. SEARCH METHODS: We conducted a systematic search of the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, and Embase, all from database inception to December 2016 and without any language restriction. We also searched ISI Web of Science, two trials registers, and grey literature. SELECTION CRITERIA: We included randomised trials, controlled before-after studies, and interrupted time series studies that compared the effects of providing feedback to physicians about their patients' adherence to prescribed long-term medications for chronic diseases versus usual care. We included published or unpublished studies in any language. Participants included any physician and any patient prescribed with long-term medication for chronic disease. We included interventions providing the prescribing physician with information about patient adherence to medication. Only studies in which feedback to the physician was the sole intervention or the essential component of a multifaceted intervention were eligible. In the comparison groups, the physicians should not have had access to information about their patients' adherence to medication. We considered the following outcomes: medication adherence, patient outcomes, health resource use, processes of care, and adverse events. DATA COLLECTION AND ANALYSIS: Two independent review authors extracted and analysed all data using standard methodological procedures expected by Cochrane and the Effective Practice and Organisation of Care group. Due to heterogeneity in study methodology, comparison groups, intervention settings, and measurements of outcomes, we did not carry out meta-analysis. We describe the impact of interventions on outcomes in tabular form and make a qualitative assessment of the effects of studies. MAIN RESULTS: We included nine studies (23,255 patient participants): eight randomised trials and one interrupted time series analysis. The studies took place in primary care and other outpatient settings in the USA and Canada. Seven interventions involved the systematic provision of feedback to physicians concerning all their patients' adherence to medication, and two interventions involved issuing an alert for non-adherent patients only. Seven studies used pharmacy refill data to assess medication adherence, and two used an electronic device or self-reporting. The definition of adherence differed across studies, making comparisons difficult. Eight studies were at high risk of bias, and one study was at unclear risk of bias. The most frequent source of bias was lack of protection against contamination.Providing physicians with feedback may lead to little or no difference in medication adherence (seven studies, 22,924 patients), patient outcomes (two studies, 1292 patients), or health resource use (two studies, 4181 patients). Providing physicians with feedback on medication adherence may improve processes of care (e.g. more medication changes, dialogue with patient, management of uncontrolled hypertension) compared to usual care (four studies, 2780 patients). None of the studies reported an adverse event due to the intervention. The certainty of evidence was low for all outcomes, mainly due to high risk of bias, high heterogeneity across studies, and indirectness of evidence. AUTHORS' CONCLUSIONS: Across nine studies, we observed little or no evidence that provision of feedback to physicians regarding their patients adherence to prescribed medication improved medication adherence, patient outcomes, or health resource use. Feedback about medication adherence may improve processes of care, but due to the small number of studies assessing this outcome and high risk of bias, we cannot draw firm conclusions on the effect of feedback on this outcome. Future research should use a clear, standardised definition of medication adherence and cluster-randomisation to avoid the risk of contamination.
[Mh] Termos MeSH primário: Retroalimentação
Adesão à Medicação/estatística & dados numéricos
Papel do Médico
[Mh] Termos MeSH secundário: Seres Humanos
Análise de Séries Temporais Interrompida
Ensaios Clínicos Controlados Aleatórios como Assunto
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180301
[Lr] Data última revisão:
180301
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180111
[St] Status:MEDLINE
[do] DOI:10.1002/14651858.CD012042.pub2


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[PMID]:29194245
[Au] Autor:McNiel PL; Elertson KM
[Ad] Endereço:About the Authors Paula L. McNiel, DNP, RN, APHN-BC, is an assistant professor, University of Wisconsin-Oshkosh College of Nursing. Kathleen M. Elertson, DNP, RN, CPNP, FNP-BC, is an assistant professor, University of Wisconsin-Oshkosh College of Nursing. For more information, write to Dr. McNiel at mcnielp@uwosh.edu.
[Ti] Título:Reality Check: Preparing Nursing Students to Respond to Ebola and Other Infectious Diseases.
[So] Source:Nurs Educ Perspect;38(1):42-43, 2017 Jan/Feb.
[Is] ISSN:1536-5026
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Escalating uncertainty regarding the international impact of Ebola virus disease and other infectious diseases prompted educators to develop interactive, multidisciplinary training for senior-level baccalaureate nursing students. A three-hour clinical learning session was scheduled within the curriculum. Nurse faculty utilized 11 activities to increase students' awareness and understanding of the potential and actual impact of Ebola virus disease and other infectious diseases. Feedback reflected a positive student experience highlighting several key areas related to increased knowledge and confidence. This session highlighted the importance of adjusting focus and priorities within curricula to meet core baccalaureate essentials and address current public health needs.
[Mh] Termos MeSH primário: Bacharelado em Enfermagem
Doença pelo Vírus Ebola/enfermagem
[Mh] Termos MeSH secundário: Currículo
Retroalimentação
Seres Humanos
Pesquisa em Educação de Enfermagem
Desenvolvimento de Programas
Estudantes de Enfermagem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180227
[Lr] Data última revisão:
180227
[Sb] Subgrupo de revista:N
[Da] Data de entrada para processamento:171202
[St] Status:MEDLINE
[do] DOI:10.1097/01.NEP.0000000000000076


  5 / 27659 MEDLINE  
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[PMID]:29277612
[Au] Autor:Lee EB; Lim HD; You SH; Cheong DE; Kim GJ
[Ad] Endereço:Department of Biological Sciences, College of Natural Sciences, Chonnam National University, Yong-Bong Dong, Buk-Gu, Gwangju 500-757, Republic of Korea.
[Ti] Título:Conditional constitutive expression system of a drug protein in vivo by positive feedback loop using an inducer-independent artificial transcription factor.
[So] Source:Biochem Biophys Res Commun;495(4):2390-2395, 2018 01 22.
[Is] ISSN:1090-2104
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Bacterial-mediated drug delivery is a potential and promising strategy for the specific treatment of cancer with therapeutic molecules, especially with genetically encoded proteins. These proteins must be tightly regulated due to cytotoxicity and thus are usually expressed under the control of the P and TetA/TetR promoters in vivo. Since protein expression from these systems is triggered by exogenous inducer, periodic intravenous injection of inducer is necessary. However, these treatments can result in non-homogenous and/or inefficient expression of therapeutic proteins in vivo due to impeded diffusion and dilution of the inducer further from the injection site. To overcome these hurdles, we designed a conditional constitutive expression system equipped with the artificial transcription factor, AraC , which has two operator-binding domains and simultaneously binds to the I and I operators of the P promoter for gene expression in an arabinose-independent manner. Using this construct and the wild type protein AraC under the control of the P promoter, we constructed a self-positive feedback system to constitutively express the therapeutic protein when the induction of AraC was triggered once using arabinose. This expression system could be useful in various cancer treatment strategies using bacteria to deliver genetically encoded drugs in vivo.
[Mh] Termos MeSH primário: Proteínas de Bactérias/genética
Preparações de Ação Retardada/administração & dosagem
Escherichia coli/genética
Engenharia Genética/métodos
Regiões Promotoras Genéticas/genética
Proteínas Recombinantes/administração & dosagem
Proteínas Recombinantes/genética
[Mh] Termos MeSH secundário: Retroalimentação
Fatores de Transcrição
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Bacterial Proteins); 0 (Delayed-Action Preparations); 0 (Recombinant Proteins); 0 (Transcription Factors)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180222
[Lr] Data última revisão:
180222
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171227
[St] Status:MEDLINE


  6 / 27659 MEDLINE  
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[PMID]:29401968
[Au] Autor:Zhang X; Zeng F; Li Y; Qiao Y
[Ti] Título:Improvement in focusing accuracy of DNA sequencing microscope with multi-position laser differential confocal autofocus method.
[So] Source:Opt Express;26(2):887-896, 2018 Jan 22.
[Is] ISSN:1094-4087
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:High focusing accuracy in microscopes could improve the imaging quality to reduce the error rate in DNA sequencing. We propose a new feedback method to improve the focusing condition to a very high accuracy. A reference laser reflected by the sample is detected by two or more sensors around the confocal point. After acquiring the signals from the out-of-focus positions, online data processing is implemented to provide feedbacks for real-time focus-plane locking on the sample surface. This method provides an accuracy better than 1/10 of the objective depth-of-focus. To balance optical aberrations, a specific optical feedback system should be designed, with athermal design considerations to adapt DNA sequencing work to temperature fluctuations.
[Mh] Termos MeSH primário: Retroalimentação
Sequenciamento de Nucleotídeos em Larga Escala/instrumentação
Microscopia Confocal/métodos
Análise de Sequência de DNA/instrumentação
[Mh] Termos MeSH secundário: Aberrometria
Sequenciamento de Nucleotídeos em Larga Escala/métodos
Lasers
Microscopia Confocal/instrumentação
Análise de Sequência de DNA/métodos
Temperatura Ambiente
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180208
[Lr] Data última revisão:
180208
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180207
[St] Status:MEDLINE
[do] DOI:10.1364/OE.26.000887


  7 / 27659 MEDLINE  
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[PMID]:28463288
[Au] Autor:Levesque L; Robaczewski A
[Ti] Título:Very accurate temperature control of bones by a CO2 laser for medical applications.
[So] Source:Appl Opt;56(13):3923-3928, 2017 May 01.
[Is] ISSN:1539-4522
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:In this paper, we show that the temperature of porcine bone samples can be maintained to a constant value within the range of 40°C-75°C. For this temperature range, it was also shown that a porcine bone sample could be kept at a given temperature within a fraction of a degree Celsius. This method relies on a real-time feedback computer control between a noncontact sensor and a CO2 laser operating at a typical repetition rate within the 5-20 kHz range. Results are shown for domesticated porcine bones that strongly absorb the CO2 radiation at λ=10.6 µm.
[Mh] Termos MeSH primário: Osso e Ossos
Retroalimentação
Temperatura Alta
Lasers de Gás
[Mh] Termos MeSH secundário: Algoritmos
Animais
Temperatura Corporal
Osso e Ossos/fisiologia
Reprodutibilidade dos Testes
Suínos
Termografia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180206
[Lr] Data última revisão:
180206
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170503
[St] Status:MEDLINE
[do] DOI:10.1364/AO.56.003923


  8 / 27659 MEDLINE  
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[PMID]:28450463
[Au] Autor:Brookes G; Baker P
[Ad] Endereço:School of English, University of Nottingham, Nottingham, UK.
[Ti] Título:What does patient feedback reveal about the NHS? A mixed methods study of comments posted to the NHS Choices online service.
[So] Source:BMJ Open;7(4):e013821, 2017 04 27.
[Is] ISSN:2044-6055
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To examine the key themes of positive and negative feedback in patients' online feedback on NHS (National Health Service) services in England and to understand the specific issues within these themes and how they drive positive and negative evaluation. DESIGN: Computer-assisted quantitative and qualitative studies of 228 113 comments (28 971 142 words) of online feedback posted to the NHS Choices website. Comments containing the most frequent positive and negative evaluative words are qualitatively examined to determine the key drivers of positive and negative feedback. PARTICIPANTS: Contributors posting comments about the NHS between March 2013 and September 2015. RESULTS: Overall, NHS services were evaluated positively approximately three times more often than negatively. The four key areas of focus were: treatment, communication, interpersonal skills and system/organisation. Treatment exhibited the highest proportion of positive evaluative comments (87%), followed by communication (77%), interpersonal skills (44%) and, finally, system/organisation (41%). Qualitative analysis revealed that reference to staff interpersonal skills featured prominently, even in comments relating to treatment and system/organisational issues. Positive feedback was elicited in cases of staff being caring, compassionate and knowing patients'' names, while rudeness, apathy and not listening were frequent drivers of negative feedback. CONCLUSIONS: Although technical competence constitutes an undoubtedly fundamental aspect of healthcare provision, staff members were much more likely to be evaluated both positively and negatively according to their interpersonal skills. Therefore, the findings reported in this study highlight the salience of such 'soft' skills to patients and emphasise the need for these to be focused upon and developed in staff training programmes, as well as ensuring that decisions around NHS funding do not result in demotivated and rushed staff. The findings also reveal a significant overlap between the four key themes in the ways that care is evaluated by patients.
[Mh] Termos MeSH primário: Comportamento de Escolha
Satisfação do Paciente/estatística & dados numéricos
Qualidade da Assistência à Saúde/estatística & dados numéricos
Medicina Estatal/normas
[Mh] Termos MeSH secundário: Inglaterra
Retroalimentação
Pesquisa sobre Serviços de Saúde
Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180201
[Lr] Data última revisão:
180201
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170429
[St] Status:MEDLINE
[do] DOI:10.1136/bmjopen-2016-013821


  9 / 27659 MEDLINE  
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[PMID]:28471483
[Au] Autor:Gao L; Bird AK; Meednu N; Dauenhauer K; Liesveld J; Anolik J; Looney RJ
[Ad] Endereço:University of Rochester Medical Center, Rochester, New York.
[Ti] Título:Bone Marrow-Derived Mesenchymal Stem Cells From Patients With Systemic Lupus Erythematosus Have a Senescence-Associated Secretory Phenotype Mediated by a Mitochondrial Antiviral Signaling Protein-Interferon-ß Feedback Loop.
[So] Source:Arthritis Rheumatol;69(8):1623-1635, 2017 08.
[Is] ISSN:2326-5205
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: Bone marrow-derived mesenchymal stem cells (BM-MSCs) create a special microenvironment for hematopoiesis and immunity and display robust immunomodulatory properties that are impaired in systemic lupus erythematosus (SLE). This study was undertaken to identify the mechanisms of defects in human SLE BM-MSCs. METHODS: Patients fulfilling SLE classification criteria and healthy controls (n = 6 per group) were recruited according to an institutional review board-approved protocol. BM-MSCs were isolated with low-density Ficoll-Hypaque, verified by flow cytometry, and studied using immunocytochemistry, real-time polymerase chain reaction, Western blotting, comet assay, ß-galactosidase assay, and RNA interference. RESULTS: SLE BM-MSCs had a senescent phenotype characterized by a reduced proliferation rate, increased production of reactive oxygen species, increased DNA damage and repair, increased expression of p53 and p16, which block the cell cycle, and altered cytokine production (increased proinflammatory cytokine production and decreased immunomodulatory cytokine production). Moreover, SLE BM-MSCs had a 5-fold increase in interferon-ß (IFNß) levels (P < 0.05 versus healthy controls) and increased IFNß-induced messenger RNAs (mRNAs), including mRNA for the intracellular nucleic acid-sensing adaptor protein mitochondrial antiviral signaling protein (MAVS), whose expression was highly correlated with IFNß levels (r > 0.9, P < 0.01). Since MAVS is known to induce IFNß production, we hypothesized that there is a positive feedback loop between MAVS and IFNß. Notably, silencing of MAVS markedly decreased IFNß, p53, and p16 protein levels and expression of mRNAs for proinflammatory cytokines. CONCLUSION: This study demonstrates a novel pathway for elevated IFNß signaling in SLE that is not dependent on stimulation by immune complexes but rather is cell intrinsic and critically mediated by IFNß and MAVS, implicating new pathways as potential therapeutic targets.
[Mh] Termos MeSH primário: Proteínas Adaptadoras de Transdução de Sinal/imunologia
Senescência Celular/imunologia
Interferon beta/imunologia
Lúpus Eritematoso Sistêmico/imunologia
Células Mesenquimais Estromais/imunologia
RNA Mensageiro/metabolismo
[Mh] Termos MeSH secundário: Proteínas Adaptadoras de Transdução de Sinal/metabolismo
Adulto
Western Blotting
Medula Óssea
Senescência Celular/genética
Inibidor p16 de Quinase Dependente de Ciclina/metabolismo
Citocinas/genética
Citocinas/imunologia
Retroalimentação
Feminino
Citometria de Fluxo
Seres Humanos
Interferon beta/genética
Lúpus Eritematoso Sistêmico/genética
Lúpus Eritematoso Sistêmico/metabolismo
Células Mesenquimais Estromais/metabolismo
Meia-Idade
Fenótipo
Interferência de RNA
Reação em Cadeia da Polimerase em Tempo Real
Transdução de Sinais
Proteína Supressora de Tumor p53/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Adaptor Proteins, Signal Transducing); 0 (Cyclin-Dependent Kinase Inhibitor p16); 0 (Cytokines); 0 (P16 protein, human); 0 (RNA, Messenger); 0 (TP53 protein, human); 0 (Tumor Suppressor Protein p53); 0 (VISA protein, human); 77238-31-4 (Interferon-beta)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:180119
[Lr] Data última revisão:
180119
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170505
[St] Status:MEDLINE
[do] DOI:10.1002/art.40142


  10 / 27659 MEDLINE  
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[PMID]:29220414
[Au] Autor:Wei L; Chen G; Yang Z; Yu T; Quan W; Li Y
[Ad] Endereço:School of Biomedical Engineering, Third Military Medical University, Chongqing, the People's Republic of China.
[Ti] Título:Detection of spontaneous pulse using the acceleration signals acquired from CPR feedback sensor in a porcine model of cardiac arrest.
[So] Source:PLoS One;12(12):e0189217, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Reliable detection of return of spontaneous circulation with minimal interruptions of chest compressions is part of high-quality cardiopulmonary resuscitation (CPR) and routinely done by checking pulsation of carotid arteries. However, manual palpation was time-consuming and unreliable even if performed by expert clinicians. Therefore, automated accurate pulse detection with minimal interruptions of chest compression is highly desirable during cardiac arrest especially in out-of-hospital settings. OBJECTIVE: To investigate whether the acceleration (ACC) signals acquired from accelerometer-based CPR feedback sensor can be used to distinguish perfusing rhythm (PR) from pulseless electrical activity (PEA) in a porcine model of cardiac arrest. METHODS: Cardiac arrest was induced in 49 male adult pigs. ECG, arterial blood pressure (ABP) and ACC waveforms were simultaneously recorded during CPR. 3-second segments containing compression-free signals during chest compression pauses were extracted and only those segments with organized rhythm were used for analysis. PR was defined as systolic arterial pressure >60 mmHg and pulse pressure >10 mmHg, while PEA was defined as an organized rhythm that does not meet the above criteria for PR. Peak correlation coefficient (CCp) of the cross-correlation function between pre-processed ECG and ACC, was used to discriminate PR and PEA. RESULTS: 63 PR and 153 PEA were identified from the total of 1025 extracted segments. CCp was significantly higher for PR as compared to PEA (0.440±0.176 vs. 0.067±0.042, p<0.01) and highly correlated with ABP (r = 0.848, p<0.001). The area under the receiver operating characteristic curve, sensitivity, specificity and accuracy were 0.965, 93.6%, 97.5% and 96.7% for the ACC-based automatic spontaneous pulse detection. CONCLUSIONS: In this animal model, the ACC signals acquired from an accelerometer-based CPR feedback sensor can be used to detect the presence of spontaneous pulse with high accuracy.
[Mh] Termos MeSH primário: Reanimação Cardiopulmonar
Modelos Animais de Doenças
Retroalimentação
Parada Cardíaca/fisiopatologia
[Mh] Termos MeSH secundário: Aceleração
Animais
Suínos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180104
[Lr] Data última revisão:
180104
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171209
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0189217



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