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[PMID]: 28466547 [Au] Autor: Inch J; Notman F; Watson M; Green D; Baird R; Ferguson J; Hind C; McKinstry B; Strath A; Bond C; Telepharmacy Research Team [Ad] Endereço: Centre of Academic Primary Care, University of Aberdeen, Aberdeen, UK. [Ti] Título: Tele-pharmacy in rural Scotland: a proof of concept study. [So] Source: Int J Pharm Pract;25(3):210-219, 2017 Jun. [Is] ISSN: 2042-7174 [Cp] País de publicação: England [La] Idioma: eng [Ab] Resumo: INTRODUCTION: Technology enables medical services to be provided to rural communities. This proof of concept study assessed the feasibility and acceptability of delivering community pharmacy services (CPS; including advice, sale of over-the-counter products and dispensing of prescriptions) by tele-technology (the Telepharmacy Robotic Supply Service (TPRSS)) to a rural population in Scotland. METHODS: Data collection included the following: postal surveys to local residents; focus groups/ interviews with pharmacists, other healthcare professionals (HCPs) and service users, at baseline and follow-up; TPRSS logs. Interviews/focus groups were audio-recorded, transcribed and thematically analysed. Descriptive statistics were reported for survey data. RESULTS: Qualitative results: Pre-installation: residents expressed satisfaction with current pharmacy access. HCPs believed the TPRSS would improve pharmacy access and reduce pressure on GPs. Concerns included costs, confidentiality, patient safety and 'fear' of technology. Post-installation: residents and pharmacy staff were positive, finding the service easy to use. Quantitative results: Pre-installation: almost half the respondents received regular prescription medicines and a third used an over-the-counter (OTC) medicine at least monthly. More than 80% (124/156) reported they would use the TPRSS. There was low awareness of the minor ailment service (MAS; 38%; 59/156). Post-installation: prescription ordering and OTC medicine purchase were used most frequently; the video link was used infrequently. Reasons for non-use were lack of need (36%; 40/112) and linkage to only one pharmacy (31%; 35/112). DISCUSSION: Community pharmacy services delivered remotely using tele-technology are feasible and acceptable. A larger study should be undertaken to confirm the potential of the TPRSS to reduce health inequalities in rural areas. [Mh] Termos MeSH primário: Farmácia/tendências Serviços de Saúde Rural/tendências Telemedicina/tendências [Mh] Termos MeSH secundário: Adolescente Adulto Idoso Idoso de 80 Anos ou mais Serviços Comunitários de Farmácia Prescrições de Medicamentos/estatística & dados numéricos Estudos de Viabilidade Feminino Acesso aos Serviços de Saúde Seres Humanos Masculino Meia-Idade Medicamentos sem Prescrição Farmacêuticos População Rural Escócia Fatores Socioeconômicos Inquéritos e Questionários Adulto Jovem [Pt] Tipo de publicação: JOURNAL ARTICLE [Nm] Nome de substância: 0 (Nonprescription Drugs) [Em] Mês de entrada: 1803 [Cu] Atualização por classe: 180308 [Lr] Data última revisão: 180308 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170504 [St] Status: MEDLINE [do] DOI: 10.1111/ijpp.12376

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[PMID]: 28453820 [Au] Autor: Bourne RS; Shulman R; Tomlin M; Borthwick M; Berry W; Mills GH [Ad] Endereço: Departments of Pharmacy and Critical Care, Sheffield Teaching Hospitals NHS Foundation Trust, Northern General Hospital, Herries Road, Sheffield S5 7 AU, UK. [Ti] Título: Reliability of clinical impact grading by healthcare professionals of common prescribing error and optimisation cases in critical care patients. [So] Source: Int J Qual Health Care;29(2):250-255, 2017 Apr 01. [Is] ISSN: 1464-3677 [Cp] País de publicação: England [La] Idioma: eng [Ab] Resumo: Objective: To identify between and within profession-rater reliability of clinical impact grading for common critical care prescribing error and optimisation cases. To identify representative clinical impact grades for each individual case. Design: Electronic questionnaire. Setting: 5 UK NHS Trusts. Participants: 30 Critical care healthcare professionals (doctors, pharmacists and nurses). Intervention: Participants graded severity of clinical impact (5-point categorical scale) of 50 error and 55 optimisation cases. Main Outcome Measures: Case between and within profession-rater reliability and modal clinical impact grading. Methods: Between and within profession rater reliability analysis used linear mixed model and intraclass correlation, respectively. Results: The majority of error and optimisation cases (both 76%) had a modal clinical severity grade of moderate or higher. Error cases: doctors graded clinical impact significantly lower than pharmacists (-0.25; P < 0.001) and nurses (-0.53; P < 0.001), with nurses significantly higher than pharmacists (0.28; P < 0.001). Optimisation cases: doctors graded clinical impact significantly lower than nurses and pharmacists (-0.39 and -0.5; P < 0.001, respectively). Within profession reliability grading was excellent for pharmacists (0.88 and 0.89; P < 0.001) and doctors (0.79 and 0.83; P < 0.001) but only fair to good for nurses (0.43 and 0.74; P < 0.001), for optimisation and error cases, respectively. Conclusions: Representative clinical impact grades for over 100 common prescribing error and optimisation cases are reported for potential clinical practice and research application. The between professional variability highlights the importance of multidisciplinary perspectives in assessment of medication error and optimisation cases in clinical practice and research. [Mh] Termos MeSH primário: Cuidados Críticos Pessoal de Saúde/psicologia Pessoal de Saúde/estatística & dados numéricos Erros de Medicação/estatística & dados numéricos [Mh] Termos MeSH secundário: Seres Humanos Corpo Clínico Hospitalar/psicologia Corpo Clínico Hospitalar/estatística & dados numéricos Recursos Humanos de Enfermagem no Hospital/psicologia Recursos Humanos de Enfermagem no Hospital/estatística & dados numéricos Farmacêuticos/psicologia Farmacêuticos/estatística & dados numéricos Garantia da Qualidade dos Cuidados de Saúde/métodos Reprodutibilidade dos Testes Inquéritos e Questionários Reino Unido [Pt] Tipo de publicação: JOURNAL ARTICLE [Em] Mês de entrada: 1711 [Cu] Atualização por classe: 180308 [Lr] Data última revisão: 180308 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170429 [St] Status: MEDLINE [do] DOI: 10.1093/intqhc/mzx003

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[PMID]: 28453819 [Au] Autor: Cheen MHH; Goon CP; Ong WC; Lim PS; Wan CN; Leong MY; Khee GY [Ad] Endereço: Department of Pharmacy, Singapore General Hospital, Singapore. [Ti] Título: Evaluation of a care transition program with pharmacist-provided home-based medication review for elderly Singaporeans at high risk of readmissions. [So] Source: Int J Qual Health Care;29(2):200-205, 2017 Apr 01. [Is] ISSN: 1464-3677 [Cp] País de publicação: England [La] Idioma: eng [Ab] Resumo: Objective: This study aimed to determine whether pharmacist-provided home-based medication review (HBMR) can reduce readmissions in the elderly. Design: Retrospective cohort study. Setting: Patient's home. Participants: Records of patients referred to a care transition program from March 2011 through March 2015 were reviewed. Patients aged 60 years and older taking more than 5 medications and had at least 2 unplanned admissions within 3 months preceding the first home visit were included. Intervention: Pharmacist-provided HBMR. Main outcome measures: Primary outcome was readmission rate over 6 months after the first home visit. Secondary outcomes included emergency department (ED) visits, outpatient visits and mortality. Drug-related problems (DRPs) were reported for the HBMR group. Multivariate incidence rate ratios (IRR) and hazard ratio (HR) were calculated with adjustments for covariates. Results: The study included 499 patients (97 HBMR, 402 no HBMR). Pharmacist-provided HBMR reduced readmissions by 26% (IRR = 0.74, 95% CI: 0.59-0.92, P = 0.007), reduced ED visits by 20% (IRR = 0.80, 95% CI: 0.66-0.98, P = 0.030) and increased outpatient visits by 16% (IRR = 1.16, 95% CI: 0.95-1.41, P = 0.150). There were 8 and 44 deaths in the HBMR and no HBMR groups respectively (HR = 0.73, 95% CI: 0.29-1.81, P = 0.492). Pharmacists identified 464 DRPs, with 169 (36.4%) resolved within 1 month after the home visit. Conclusions: The study suggests that pharmacist-provided HBMR is effective in reducing readmissions and ED visits in the elderly. More studies in the Asian population are needed to determine its long term benefits and patient's acceptability. [Mh] Termos MeSH primário: Reconciliação de Medicamentos/métodos Alta do Paciente Readmissão do Paciente/estatística & dados numéricos Farmacêuticos [Mh] Termos MeSH secundário: Idoso Idoso de 80 Anos ou mais Estudos de Coortes Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos/prevenção & controle Serviço Hospitalar de Emergência/utilização Feminino Seres Humanos Masculino Meia-Idade Mortalidade Serviço de Farmácia Hospitalar/métodos Estudos Retrospectivos Singapura [Pt] Tipo de publicação: EVALUATION STUDIES; JOURNAL ARTICLE [Em] Mês de entrada: 1711 [Cu] Atualização por classe: 180308 [Lr] Data última revisão: 180308 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170429 [St] Status: MEDLINE [do] DOI: 10.1093/intqhc/mzw150

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[PMID]: 29419379 [Au] Autor: Yeung EYH [Ad] Endereço: Royal Lancaster Infirmary, Lancaster LA1 4RP, UK. [Ti] Título: GPs to judge which patients deserve an NHS prescription. [So] Source: BMJ;360:k404, 2018 02 01. [Is] ISSN: 1756-1833 [Cp] País de publicação: England [La] Idioma: eng [Mh] Termos MeSH primário: Prescrições de Medicamentos/economia Médicos/legislação & jurisprudência Medicina Estatal/economia [Mh] Termos MeSH secundário: Necessidades e Demandas de Serviços de Saúde Seres Humanos Cobertura do Seguro/normas Farmacêuticos/ética Qualidade da Assistência à Saúde/normas Medicina Estatal/legislação & jurisprudência [Pt] Tipo de publicação: LETTER [Em] Mês de entrada: 1803 [Cu] Atualização por classe: 180305 [Lr] Data última revisão: 180305 [Sb] Subgrupo de revista: AIM; IM [Da] Data de entrada para processamento: 180209 [St] Status: MEDLINE [do] DOI: 10.1136/bmj.k404

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[PMID]: 29386438 [Au] Autor: Niki K; Takemura M; Kitagawa K; Shimizu R; Takahashi Y; Hatabu A; Uejima E [Ad] Endereço: Department of Clinical Pharmacy Research and Education, Graduate School of Pharmaceutical Sciences, Osaka University. [Ti] Título: [The Present Implementation Status and Problems of Vital-signs Measurement by Community Pharmacists in Home Medical Care in Osaka]. [So] Source: Yakugaku Zasshi;138(2):243-250, 2018. [Is] ISSN: 1347-5231 [Cp] País de publicação: Japan [La] Idioma: jpn [Ab] Resumo: 　While the community-based integrated care systems are in the process of being structured currently, more and more community pharmacists want to learn physical assessment skills. However, no large-scale survey focusing on present implementation status and problems of physical assessment by community pharmacists has been conducted yet. Osaka has the 2nd highest number of community pharmacies in Japan now, and the population aged ≥65 years will be expected to become the 3rd highest in 2025. Thus, Osaka can become a national leading model case for community pharmacists' activity in future home medical care. Therefore, this study aimed to reveal the present implementation status and problems of physical assessment by community pharmacists in Osaka, especially focusing on vital-signs. The questionnaires were sent to all the 3571 insurance pharmacies belonging to the Osaka Pharmaceutical Association and 871 pharmacies responded. Many pharmacists recognized the necessity for vital-signs measurement by pharmacists in home medical care (81.5% of pharmacies that offered home medical care and 75.4% of pharmacies that did not offer one). However, the proportion of pharmacies that conduct vital-signs measurement in home medical care was 18.7%, therefore, it was suggested that the present problem is "many pharmacists cannot conduct vital-signs measurement, although they think it should be conducted". Moreover, the most common reason for not measuring vital-signs was the lack of instruments, such as stethoscopes and sphygmomanometer (43.2%). This is the latest report with a large-scale sample, thus, it can serve as valuable knowledge in considering what pharmacists do for the future. [Mh] Termos MeSH primário: Serviços Comunitários de Farmácia Serviços de Assistência Domiciliar Farmacêuticos Papel Profissional Sinais Vitais [Mh] Termos MeSH secundário: Competência Clínica Serviços Comunitários de Farmácia/tendências Serviços de Assistência Domiciliar/tendências Seres Humanos Japão Inquéritos e Questionários [Pt] Tipo de publicação: JOURNAL ARTICLE [Em] Mês de entrada: 1802 [Cu] Atualização por classe: 180228 [Lr] Data última revisão: 180228 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 180202 [St] Status: MEDLINE [do] DOI: 10.1248/yakushi.17-00152

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[PMID]: 29386431 [Au] Autor: Ohashi Y [Ad] Endereço: Quality & Regulatory Compliance Unit, Chugai Pharmaceutical Co., Ltd. [Ti] Título: [Safe Use of Recent New Drugs-Current Status and Challenges]. [So] Source: Yakugaku Zasshi;138(2):177-183, 2018. [Is] ISSN: 1347-5231 [Cp] País de publicação: Japan [La] Idioma: jpn [Ab] Resumo: 　In Japan and overseas, Chugai Pharmaceutical Company handles numerous biopharmaceuticals, molecular targeted therapies and other pharmaceuticals with innovative modes of action. Expert safety evaluation is essential for promoting the appropriate use of these pharmaceuticals around the world and in gaining acceptance from patients and healthcare professionals (HCPs), while speedy decision-making is crucial for the timely collection and provision of safety information and thus ensuring safety. In 2015, we collected safety information on more than 180000 cases and evaluated it from a medical standpoint. We have established a system for recording the collected information in a global database, and are conducting signal detection of adverse drug reactions using this database. With this system, we promptly disclose information to regulatory authorities in Japan, the US, Europe and Asia. We have in-house medical doctors with abundant clinical experience who conduct expert safety evaluations. Many innovative drugs, such as anticancer drugs or biopharmaceuticals, require wider-ranging, more rigorous management, including the provision of appropriate safety information to HCPs, management of distribution through wholesalers and dispensing pharmacies, and confirmation of conditions of use, in addition to all-case registration surveillance. With progress in the development of individualized medicine and drugs with new modes of action, in order for HCPs to understand the characteristics of these new drugs and use them appropriately, pharmacists and pharmaceutical companies should cooperate in promoting their appropriate use in the spirit of 'All Pharmacists for Patients'. [Mh] Termos MeSH primário: Bases de Dados de Produtos Farmacêuticos Serviços de Informação sobre Medicamentos Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos Preparações Farmacêuticas Farmacovigilância Gestão de Riscos [Mh] Termos MeSH secundário: Biofarmácia Tomada de Decisões Gerenciais Indústria Farmacêutica Seres Humanos Farmacêuticos Medicina de Precisão/tendências Segurança [Pt] Tipo de publicação: JOURNAL ARTICLE [Nm] Nome de substância: 0 (Pharmaceutical Preparations) [Em] Mês de entrada: 1802 [Cu] Atualização por classe: 180228 [Lr] Data última revisão: 180228 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 180202 [St] Status: MEDLINE [do] DOI: 10.1248/yakushi.17-00174-3

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[PMID]: 29234797 [Au] Autor: Gomez AM [Ad] Endereço: Sexual Health and Reproductive Equity Program, School of Social Welfare, University of California, Berkeley. [Ti] Título: Availability of Pharmacist-Prescribed Contraception in California, 2017. [So] Source: JAMA;318(22):2253-2254, 2017 Dec 12. [Is] ISSN: 1538-3598 [Cp] País de publicação: United States [La] Idioma: eng [Mh] Termos MeSH primário: Anticoncepcionais Femininos Prescrições de Medicamentos/estatística & dados numéricos Farmácias/estatística & dados numéricos [Mh] Termos MeSH secundário: California Seres Humanos Farmacêuticos Honorários por Prescrição de Medicamentos/estatística & dados numéricos [Pt] Tipo de publicação: JOURNAL ARTICLE [Nm] Nome de substância: 0 (Contraceptive Agents, Female) [Em] Mês de entrada: 1712 [Cu] Atualização por classe: 180228 [Lr] Data última revisão: 180228 [Sb] Subgrupo de revista: AIM; IM [Da] Data de entrada para processamento: 171214 [St] Status: MEDLINE [do] DOI: 10.1001/jama.2017.15674

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[PMID]: 29216614 [Au] Autor: International Academy of Compounding Pharmacists [Ti] Título: IACP Legislative/Regulatory Update. [So] Source: Int J Pharm Compd;21(5):382-383, 2017 Sep-Oct. [Is] ISSN: 1092-4221 [Cp] País de publicação: United States [La] Idioma: eng [Mh] Termos MeSH primário: Composição de Medicamentos Controle de Medicamentos e Entorpecentes Farmacêuticos [Mh] Termos MeSH secundário: Seres Humanos [Pt] Tipo de publicação: NEWS [Em] Mês de entrada: 1802 [Cu] Atualização por classe: 180220 [Lr] Data última revisão: 180220 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 171208 [St] Status: MEDLINE

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[PMID]: 29216612 [Au] Autor: Allen LV [Ad] Endereço: International Journal of Pharmaceutical Compounding. lallen@ijpc.com. [Ti] Título: Child-safety Containers/Devices and Compounding. [So] Source: Int J Pharm Compd;21(5):364-370, 2017 Sep-Oct. [Is] ISSN: 1092-4221 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: The U.S. Consumer Product Safety Commission has been around since it was created in 1972 through the Consumer Product Safety Act. Its purpose is to protect "against unreasonable risks of injuries associated with consumer products." Manufactured drugs must meet the standards unless specifically exempted. Dispensing and compounding pharmacists must also meet the standards. Due to a smaller market size, compliant products to meet the U.S. Consumer Product Safety Commission's standards to aid compounding pharmacists have been slow in coming. However, now there are numerous different products, some introduced recently, which make it easier for compounding pharmacists to comply with the standards. The new technologies are innovative and serve a great need. [Mh] Termos MeSH primário: Segurança de Produtos ao Consumidor Composição de Medicamentos Embalagem de Medicamentos [Mh] Termos MeSH secundário: Criança Seres Humanos Farmacêuticos [Pt] Tipo de publicação: JOURNAL ARTICLE [Em] Mês de entrada: 1802 [Cu] Atualização por classe: 180220 [Lr] Data última revisão: 180220 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 171208 [St] Status: MEDLINE

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[PMID]: 29216611 [Au] Autor: Biundo B [Ad] Endereço: Professional Compounding Centers of America, Houston, Texas. bbiundo@pccarx.com. [Ti] Título: Compounding Opportunities in Urology. [So] Source: Int J Pharm Compd;21(5):358-362, 2017 Sep-Oct. [Is] ISSN: 1092-4221 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: There are a lot of options that pharmacists, including compounding pharmacists, can offer urologists to assist their patients. Compounding pharmacists are in a great position to offer unique, effective preparations for many of the conditions urologists treat on a daily basis. It would be well worth the time to learn a little about the conditions these specialists treat and become familiar with what you can offer. [Mh] Termos MeSH primário: Composição de Medicamentos Farmacêuticos Urologia [Mh] Termos MeSH secundário: Cistite Intersticial/tratamento farmacológico Disfunção Erétil/tratamento farmacológico Seres Humanos Infertilidade/tratamento farmacológico Masculino Dor Pélvica/tratamento farmacológico Induração Peniana/tratamento farmacológico [Pt] Tipo de publicação: JOURNAL ARTICLE [Em] Mês de entrada: 1802 [Cu] Atualização por classe: 180220 [Lr] Data última revisão: 180220 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 171208 [St] Status: MEDLINE

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