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[PMID]: 28499012 [Au] Autor: Latimer CS; Keene CD; Flanagan ME; Hemmy LS; Lim KO; White LR; Montine KS; Montine TJ [Ad] Endereço: From the Department of Pathology, University of Washington, Seattle, Washington (CSL, CDK); Department of Pathology, Stanford University, Stanford, California (MEF, KSM, TJM); Department of Psychiatry, University of Minnesota, Minneapolis, Minnesota (LSH, KOL); Geriatric Research, Education, and Cli [Ti] Título: Resistance to Alzheimer Disease Neuropathologic Changes and Apparent Cognitive Resilience in the Nun and Honolulu-Asia Aging Studies. [So] Source: J Neuropathol Exp Neurol;76(6):458-466, 2017 Jun 01. [Is] ISSN: 1554-6578 [Cp] País de publicação: England [La] Idioma: eng [Ab] Resumo: Two population-based studies key to advancing knowledge of brain aging are the Honolulu-Asia Aging Study (HAAS) and the Nun Study. Harmonization of their neuropathologic data allows cross comparison, with findings common to both studies likely generalizable, while distinct observations may point to aging brain changes that are dependent on sex, ethnicity, environment, or lifestyle factors. Here, we expanded the neuropathologic evaluation of these 2 studies using revised NIA-Alzheimer's Association guidelines and compared directly the neuropathologic features of resistance and apparent cognitive resilience. There were significant differences in prevalence of Alzheimer disease neuropathologic change, small vessel vascular brain injury, and Lewy body disease between these 2 studies, suggesting that sex, ethnicity, and lifestyle factors may significantly influence resistance to developing brain injury with age. In contrast, hippocampal sclerosis prevalence was very similar, but skewed to poorer cognitive performance, suggesting that hippocampal sclerosis could act sequentially with other diseases to impair cognitive function. Strikingly, despite these observed differences, the proportion of individuals resistant to all 4 diseases of brain or displaying apparent cognitive resilience was virtually identical between HAAS and Nun Study participants. Future in vivo validation of these results awaits comprehensive biomarkers of these 4 brain diseases. [Mh] Termos MeSH primário: Envelhecimento/fisiologia Envelhecimento/psicologia Doença de Alzheimer/patologia Doença de Alzheimer/psicologia Cognição Freiras Resiliência Psicológica [Mh] Termos MeSH secundário: Idoso Idoso de 80 Anos ou mais Biomarcadores Doenças de Pequenos Vasos Cerebrais/patologia Estudos de Coortes Efeitos Psicossociais da Doença Grupos Étnicos Feminino Hawaii Hipocampo/patologia Seres Humanos Doença por Corpos de Lewy/patologia Estilo de Vida Masculino Caracteres Sexuais [Pt] Tipo de publicação: JOURNAL ARTICLE [Nm] Nome de substância: 0 (Biomarkers) [Em] Mês de entrada: 1707 [Cu] Atualização por classe: 171005 [Lr] Data última revisão: 171005 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170513 [St] Status: MEDLINE [do] DOI: 10.1093/jnen/nlx030

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[PMID]: 27146050 [Au] Autor: Merakou K; Taki S; Barbouni A; Antoniadou E; Theodoridis D; Karageorgos G; Kourea-Kremastinou J [Ad] Endereço: Department of Public Health, National School of Public Health, 196, Alexandras Ave., 11521, Athens, Greece. kmerakou@esdy.edu.gr. [Ti] Título: Sense of Coherence (SOC) in Christian Orthodox Monks and Nuns in Greece. [So] Source: J Relig Health;56(2):521-529, 2017 Apr. [Is] ISSN: 1573-6571 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: This paper aims to investigate the stress management skills of Christian Orthodox monks and nuns, as measured by Antonovsky's scale sense of coherence (SOC). A case-control study was designed to test the hypotheses whether monks and nuns have higher SOC than secular people. The study population consisted of 193 individuals, 96 monks and nuns (study group) and 97 secular men and women (control group). SOC score was higher in monks and nuns as compared to the secular population (p = 0.002), men as compared to women (p = 0.012) and persons of older age (p = 0.004) as compared to younger individuals. [Mh] Termos MeSH primário: Cristianismo/psicologia Monges/psicologia Freiras/psicologia Religião e Psicologia Senso de Coerência Estresse Psicológico/psicologia [Mh] Termos MeSH secundário: Adulto Estudos de Casos e Controles Feminino Grécia Seres Humanos Masculino Distribuição por Sexo Inquéritos e Questionários [Pt] Tipo de publicação: JOURNAL ARTICLE [Em] Mês de entrada: 1710 [Cu] Atualização por classe: 171027 [Lr] Data última revisão: 171027 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 160506 [St] Status: MEDLINE [do] DOI: 10.1007/s10943-016-0244-5

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[PMID]: 26697881 [Au] Autor: Tan L; Sim LK; Ng L; Toh HJ; Low JA [Ad] Endereço: 1 Palliative Care Service, Department of Geriatric Medicine, Khoo Teck Puat Hospital, Singapore. [Ti] Título: Advance Care Planning. [So] Source: Am J Hosp Palliat Care;34(1):26-33, 2017 Feb. [Is] ISSN: 1938-2715 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: There has been a growing trend in addressing spiritual needs in caring for the person, especially nearing the end of one's life. Advance care planning (ACP) facilitates understanding of preferences and explores the spiritual and existential aspects of care. This study explores the views and preferences of a group of Catholic nuns in Singapore, specifically looking at what was meaningful and valuable to them when determining treatment options at the end of life. Twenty-three nuns were purposively recruited in July 2012. A focus group discussion was conducted after administration of a questionnaire and attendance at a 1-hour talk on ACP. Slightly more than half had heard of ACP prior to the talk. The majority agreed that ACP was not against their religious beliefs" and that quality of life was important to them. The themes that emerged from this study were autonomy and freedom, spirituality and quality of life, and the meaning of ACP. The findings of this study suggested that spirituality and faith define the way the participants lived their lives, including their views and preferences on end-of-life care. Integrating spirituality into an essential domain of care will help the spiritual community honor a crucial part of end-of-life discussions and afford a greater discernment of the deep meaning that ACP holds. [Mh] Termos MeSH primário: Planejamento Antecipado de Cuidados Atitude Frente à Saúde Freiras/psicologia [Mh] Termos MeSH secundário: Adulto Idoso Atitude Frente à Morte Catolicismo/psicologia Feminino Grupos Focais Seres Humanos Masculino Meia-Idade Singapura Espiritualidade Inquéritos e Questionários Assistência Terminal/psicologia [Pt] Tipo de publicação: JOURNAL ARTICLE [Em] Mês de entrada: 1707 [Cu] Atualização por classe: 170714 [Lr] Data última revisão: 170714 [Sb] Subgrupo de revista: IM; N [Da] Data de entrada para processamento: 151225 [St] Status: MEDLINE [do] DOI: 10.1177/1049909115615563

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[PMID]: 27438730 [Au] Autor: Martins Wde S [Ad] Endereço: Professor, Instituto de História e Programa de Pós-graduação em História Social /Universidade Federal do Rio de Janeiro. Largo de São Francisco de Paula, 1, sala 201. 20051-070 - Rio de Janeiro - RJ - Brasil. williamsmartins@uol.com.br. [Ti] Título: [Disease in the cloisters: requests to leave Convento da Ajuda, Rio de Janeiro, for the treatment of contagious diseases, c.1750-1780]. [Ti] Título: A clausura enferma: petições para a saída do Convento da Ajuda no Rio de Janeiro para tratamento de doenças contagiosas, c.1750-1780.. [So] Source: Hist Cienc Saude Manguinhos;23(3):719-32, 2016 Jul-Sep. [Is] ISSN: 1678-4758 [Cp] País de publicação: Brazil [La] Idioma: por [Ab] Resumo: This article discusses the requests submitted by nuns from Convento da Ajuda (Ajuda Convent) to leave their life of enclosure to receive treatment for contagious diseases. Disease was one of the few cases in which nuns were granted permission to leave. The female orders were strictly cloistered in order to preserve their purity as virgins consecrated to Christ. Extant documents detail the causes of the diseases, the ways they were transmitted, and the treatments used to fight them. These processes shed light on the procedures adopted outside the cloisters so that the nuns did not jeopardize their reclusion and honor when they went to distant places in search of treatment. [Mh] Termos MeSH primário: Catolicismo/história Doenças Transmissíveis/história Freiras/história Religião e Medicina [Mh] Termos MeSH secundário: Brasil Doenças Transmissíveis/terapia Doenças Transmissíveis/transmissão Feminino História do Século XVIII Seres Humanos Hanseníase/história Hanseníase/terapia Tuberculose/história Tuberculose/terapia [Pt] Tipo de publicação: HISTORICAL ARTICLE; JOURNAL ARTICLE [Em] Mês de entrada: 1707 [Cu] Atualização por classe: 170707 [Lr] Data última revisão: 170707 [Sb] Subgrupo de revista: QIS [Da] Data de entrada para processamento: 160721 [St] Status: MEDLINE

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[PMID]: 27281933 [Au] Autor: Simon L; Lafont O [Ti] Título: [The complex travel of cinchona barks between Peru and Québec Hôtel-Dieu, in the middle of the eighteenth century]. [Ti] Título: Le circuit complexe du quinquina entre le Pérou et l'Hôtel-Dieu de Québec, au milieu du XVIIIe siècle.. [So] Source: Rev Hist Pharm (Paris);64(389):53-8, 2016 Mar. [Is] ISSN: 0035-2349 [Cp] País de publicação: France [La] Idioma: fre [Ab] Resumo: Duplessis sisters, who were religious nuns in Hôtel-Dieu (Quebec hospital), were exchanging letters with a French apothecary from Dieppe in Normandy, named Jacques-Tranquilain Féret. They asked him to send them in Quebec the drugs and medicines their apothecary needed. Amongst these drugs were cinchona barks that came from Callao in Peru by boat, passed Cape Horn and then sailed to Cadiz, the great Spanish port. Then they embarked to Rouen, which was the French port for goods coming from overseas. The goods from Peru had then to be transported on little fishing boats to Dieppe, where Féret received the barks. The apothecary sent these drugs to Quebec by boats sailing either from Rouen or from La Rochelle. So these Peruvian drugs had to cross two times the Ocean before accessing to North America. [Mh] Termos MeSH primário: Cinchona Fitoterapia/história [Mh] Termos MeSH secundário: História do Século XVIII Seres Humanos Freiras Peru Farmacognosia/história Quebeque [Pt] Tipo de publicação: ENGLISH ABSTRACT; HISTORICAL ARTICLE; JOURNAL ARTICLE [Em] Mês de entrada: 1606 [Cu] Atualização por classe: 160610 [Lr] Data última revisão: 160610 [Sb] Subgrupo de revista: QIS [Da] Data de entrada para processamento: 160611 [St] Status: MEDLINE

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[PMID]: 26888993 [Au] Autor: White LR; Edland SD; Hemmy LS; Montine KS; Zarow C; Sonnen JA; Uyehara-Lock JH; Gelber RP; Ross GW; Petrovitch H; Masaki KH; Lim KO; Launer LJ; Montine TJ [Ad] Endereço: From the Pacific Health Research and Education Institute (L.R.W., R.P.G., G.W.R., H.P.); Departments of Geriatric Medicine (L.R.W., H.P., K.H.M.), Pathology (J.H.U.-L.), and Medicine (G.W.R., H.P.), University of Hawaii John A. Burns School of Medicine, Honolulu; Laboratory of Epidemiology and Popul [Ti] Título: Neuropathologic comorbidity and cognitive impairment in the Nun and Honolulu-Asia Aging Studies. [So] Source: Neurology;86(11):1000-8, 2016 Mar 15. [Is] ISSN: 1526-632X [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: OBJECTIVE: To examine frequencies and relationships of 5 common neuropathologic abnormalities identified at autopsy with late-life cognitive impairment and dementia in 2 different autopsy panels. METHODS: The Nun Study (NS) and the Honolulu-Asia Aging Study (HAAS) are population-based investigations of brain aging that included repeated cognitive assessments and comprehensive brain autopsies. The neuropathologic abnormalities assessed were Alzheimer disease (AD) neuropathologic changes, neocortical Lewy bodies (LBs), hippocampal sclerosis, microinfarcts, and low brain weight. Associations with screening tests for cognitive impairment were examined. RESULTS: Neuropathologic abnormalities occurred at levels ranging from 9.7% to 43%, and were independently associated with cognitive impairment in both studies. Neocortical LBs and AD changes were more frequent among the predominantly Caucasian NS women, while microinfarcts were more common in the Japanese American HAAS men. Comorbidity was usual and very strongly associated with cognitive impairment. Apparent cognitive resilience (no cognitive impairment despite Braak stage V) was strongly associated with minimal or no comorbid abnormalities, with fewer neocortical AD lesions, and weakly with longer interval between final testing and autopsy. CONCLUSIONS: Total burden of comorbid neuropathologic abnormalities, rather than any single lesion type, was the most relevant determinant of cognitive impairment in both cohorts, often despite clinical diagnosis of only AD. These findings emphasize challenges to dementia pathogenesis and intervention research and to accurate diagnoses during life. [Mh] Termos MeSH primário: Envelhecimento/patologia Doença de Alzheimer/diagnóstico Doença de Alzheimer/epidemiologia Encéfalo/patologia Transtornos Cognitivos/diagnóstico Transtornos Cognitivos/epidemiologia Freiras [Mh] Termos MeSH secundário: Idoso Idoso de 80 Anos ou mais Envelhecimento/psicologia Doença de Alzheimer/psicologia Ásia/epidemiologia Transtornos Cognitivos/psicologia Estudos de Coortes Comorbidade Feminino Hawaii/epidemiologia Seres Humanos Corpos de Lewy/patologia Freiras/psicologia [Pt] Tipo de publicação: JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL; RESEARCH SUPPORT, N.I.H., INTRAMURAL; RESEARCH SUPPORT, NON-U.S. GOV'T; RESEARCH SUPPORT, U.S. GOV'T, NON-P.H.S. [Em] Mês de entrada: 1607 [Cu] Atualização por classe: 170611 [Lr] Data última revisão: 170611 [Sb] Subgrupo de revista: AIM; IM [Da] Data de entrada para processamento: 160219 [St] Status: MEDLINE [do] DOI: 10.1212/WNL.0000000000002480

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[PMID]: 26841840 [Au] Autor: Bediaga B; Peixoto AL; Filgueiras TS [Ad] Endereço: Pesquisadora, Instituto de Pesquisas Jardim Botânico do Rio de Janeiro. Rua Pacheco Leão, 915 22460-030 - Rio de Janeiro - RJ - Brasil. begonha@jbrj.gov.br. [Ti] Título: [Maria Bandeira: a pioneering botanist at the Botanic Garden of Rio de Janeiro]. [Ti] Título: Maria Bandeira: uma botânica pioneira no Jardim Botânico do Rio de Janeiro.. [So] Source: Hist Cienc Saude Manguinhos;23(3):799-822, 2016 Jul-Sep. [Is] ISSN: 1678-4758 [Cp] País de publicação: Brazil [La] Idioma: por [Ab] Resumo: This article sheds light on Maria Bandeira, the first female botanist to work at the Botanic Garden of Rio de Janeiro. She was active in the 1920s, but is absent from the historiography and little cited in the scientific literature. The significant number of plant, fungus, and lichen specimens she collected, her capacity to reach far-flung places, her extensive correspondence with foreign experts, and her studies at Sorbonne are all sources for the analysis of the way botany was practiced and the social networks at play in science at the time. The end of her scientific career, when she adopted a cloistered life with the Barefoot Carmelite nuns, can be interpreted variously, and partially explains why her contributions to Brazilian botany have been forgotten. [Mh] Termos MeSH primário: Botânica/história Jardins/história [Mh] Termos MeSH secundário: Brasil Feminino História do Século XX Seres Humanos Freiras/história [Pt] Tipo de publicação: BIOGRAPHY; HISTORICAL ARTICLE; JOURNAL ARTICLE; PORTRAITS [Ps] Nome de pessoa como assunto: Bandeira M [Em] Mês de entrada: 1707 [Cu] Atualização por classe: 170707 [Lr] Data última revisão: 170707 [Sb] Subgrupo de revista: QIS [Da] Data de entrada para processamento: 160205 [St] Status: MEDLINE

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[PMID]: 26193971 [Au] Autor: Smeltzer CH [Ad] Endereço: Sisters of Charity of Nazareth, Nazareth, KY. [Ti] Título: Sixty Girls, Three Nuns, One Home. [So] Source: Nurs Forum;51(2):136-8, 2016 Apr. [Is] ISSN: 1744-6198 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: This article describes the experience of a nurse volunteer working with girls in India who had been trafficked and/or were children of mothers who were (are) prostitutes. The article describes how nuns who care, provide values and a safe home give the girls opportunities. The article illustrates how, with little recourse, three nuns care for 60 girls living in one home. The girls range in age from 4 to 18 years. The girls are motivated to live happily, work hard, study often, and play together. Lessons learned from the nurse volunteer who worked and lived with the girls are described. This article illustrates how nurses in retirement can still fulfill their passion of helping others. [Mh] Termos MeSH primário: Tráfico de Pessoas/psicologia Voluntários/psicologia Populações Vulneráveis/psicologia [Mh] Termos MeSH secundário: Adolescente Criança Feminino Seres Humanos Índia Acontecimentos que Mudam a Vida Freiras [Pt] Tipo de publicação: JOURNAL ARTICLE [Em] Mês de entrada: 1703 [Cu] Atualização por classe: 170327 [Lr] Data última revisão: 170327 [Sb] Subgrupo de revista: N [Da] Data de entrada para processamento: 150722 [St] Status: MEDLINE [do] DOI: 10.1111/nuf.12141

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[PMID]: 25982961 [Au] Autor: Wells JS; Bergin M [Ad] Endereço: School of Health Sciences, Waterford Institute of Technology, Waterford, Ireland. [Ti] Título: British Icons and Catholic perfidy--Anglo-Saxon historiography and the battle for Crimean War nursing. [So] Source: Nurs Inq;23(1):42-51, 2016 Mar. [Is] ISSN: 1440-1800 [Cp] País de publicação: Australia [La] Idioma: eng [Ab] Resumo: Taking as its starting point Carr's view that historical narrative reflects the preoccupations of the time in which it is written and Foucault's concept of consensual historical discourse as the outcome of a social struggle in which the victor suppresses or at least diminishes contrary versions of historical events in favour of their own, this paper traces and discusses the historical narrative of British nursing in the Crimean war and, in particular, three competing narratives that have arisen in the latter half of the 20th century and the first decade of the 21st. These are the established narrative surrounding Florence Nightingale, the new narrative surrounding Mary Seacole and an Irish narrative surrounding the role of the Sisters of Mercy. It is argued that the increased vehemence of the debate surrounding these narratives is representative of the changes that have taken place in British society. However, we also argue that the Irish narrative and its critique are reflective of deep-rooted Anglo-Protestant attitudes articulated by Nightingale and uncritically accepted by subsequent historians even in modern British historiography. [Mh] Termos MeSH primário: Afroamericanos/história Catolicismo/história Guerra da Crimeia História da Enfermagem Filosofia em Enfermagem/história [Mh] Termos MeSH secundário: Dissidências e Disputas Historiografia História do Século XIX História do Século XX Seres Humanos Irlanda Narração Freiras/história Reino Unido [Pt] Tipo de publicação: BIOGRAPHY; HISTORICAL ARTICLE; JOURNAL ARTICLE [Ps] Nome de pessoa como assunto: Nightingale F; Seacole M [Em] Mês de entrada: 1701 [Cu] Atualização por classe: 170127 [Lr] Data última revisão: 170127 [Sb] Subgrupo de revista: N [Da] Data de entrada para processamento: 150519 [St] Status: MEDLINE [do] DOI: 10.1111/nin.12104

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[PMID]: 26327531 [Au] Autor: McGowan A; Silvestri G; Moore E; Silvestri V; Patterson CC; Maxwell AP; McKay GJ [Ad] Endereço: Centre for Public Health, Queen's University Belfast, Belfast, Northern Ireland. [Ti] Título: Evaluation of the Retinal Vasculature in Hypertension and Chronic Kidney Disease in an Elderly Population of Irish Nuns. [So] Source: PLoS One;10(9):e0136434, 2015. [Is] ISSN: 1932-6203 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: BACKGROUND: Chronic kidney disease (CKD) and hypertension are global public health problems associated with considerable morbidity, premature mortality and attendant healthcare costs. Previous studies have highlighted that non-invasive examination of the retinal microcirculation can detect microvascular pathology that is associated with systemic disorders of the circulatory system such as hypertension. We examined the associations between retinal vessel caliber (RVC) and fractal dimension (DF), with both hypertension and CKD in elderly Irish nuns. METHODS: Data from 1233 participants in the cross-sectional observational Irish Nun Eye Study (INES) were assessed from digital photographs with a standardized protocol using computer-assisted software. Multivariate regression analyses were used to assess associations with hypertension and CKD, with adjustment for age, body mass index (BMI), refraction, fellow eye RVC, smoking, alcohol consumption, ischemic heart disease (IHD), cerebrovascular accident (CVA), diabetes and medication use. RESULTS: In total, 1122 (91%) participants (mean age: 76.3 [range: 56-100] years) had gradable retinal images of sufficient quality for blood vessel assessment. Hypertension was significantly associated with a narrower central retinal arteriolar equivalent (CRAE) in a fully adjusted analysis (P = 0.002; effect size = -2.16 µm; 95% confidence intervals [CI]: -3.51, -0.81 µm). No significant associations between other retinal vascular parameters and hypertension or between any retinal vascular parameters and CKD were found. CONCLUSIONS: Individuals with hypertension have significantly narrower retinal arterioles which may afford an earlier opportunity for tailored prevention and treatment options to optimize the structure and function of the microvasculature, providing additional clinical utility. No significant associations between retinal vascular parameters and CKD were detected. [Mh] Termos MeSH primário: Hipertensão/patologia Insuficiência Renal Crônica/patologia Vasos Retinianos/patologia [Mh] Termos MeSH secundário: Idoso Pressão Sanguínea Estudos Transversais Feminino Seres Humanos Irlanda Microcirculação Freiras Retina/patologia [Pt] Tipo de publicação: JOURNAL ARTICLE; OBSERVATIONAL STUDY; RESEARCH SUPPORT, NON-U.S. GOV'T [Em] Mês de entrada: 1605 [Cu] Atualização por classe: 161019 [Lr] Data última revisão: 161019 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 150902 [St] Status: MEDLINE [do] DOI: 10.1371/journal.pone.0136434

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