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[PMID]:29202957
[Au] Autor:Klosky JL; Flynn JS; Lehmann V; Russell KM; Wang F; Hardin RN; Eddinger JR; Zhang H; Schenck LA; Schover LR
[Ad] Endereço:Department of Psychology, St. Jude Children's Research Hospital, Memphis, Tennessee. Electronic address: james.klosky@stjude.org.
[Ti] Título:Parental influences on sperm banking attempts among adolescent males newly diagnosed with cancer.
[So] Source:Fertil Steril;108(6):1043-1049, 2017 Dec.
[Is] ISSN:1556-5653
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To investigate the influence of parental sociodemographic, communication, and psychological factors on sperm collection attempts among at-risk adolescent males newly diagnosed with cancer. DESIGN: Prospective, single group, observational study design. SETTING: Pediatric oncology centers. PATIENT(S): Parents (N = 144) of 122 newly diagnosed adolescent males at increased risk for infertility secondary to cancer therapy. INTERVENTION(S): Survey-based assessment of parent factors associated with adolescent collection attempts. MAIN OUTCOME MEASURE(S): Attempt of manual collection of sperm. RESULT(S): Parental recommendation to bank sperm (odds ratio [OR] 3.72; 95% confidence interval [CI] 1.18-11.76) and perceived self-efficacy to facilitate banking (OR 1.20; 95% CI 1.02-1.41) were associated with an increased likelihood of making a collection attempt. CONCLUSION(S): Parental recommendation to bank is a critical influence for sperm banking among adolescent males newly diagnosed with cancer. These findings highlight the importance of effective communication between parents, patients, and health-care teams when discussing preservation options. Parent perceptions of their ability to facilitate sperm banking at the time of diagnosis should also be targeted in future interventions. CLINICAL TRIAL REGISTRATION NUMBER: NCT01152268.
[Mh] Termos MeSH primário: Comportamento do Adolescente
Antineoplásicos/efeitos adversos
Preservação da Fertilidade/métodos
Fertilidade/efeitos dos fármacos
Fertilidade/efeitos da radiação
Conhecimentos, Atitudes e Prática em Saúde
Infertilidade Masculina/etiologia
Neoplasias/terapia
Pais/psicologia
Bancos de Esperma
Espermatozoides
[Mh] Termos MeSH secundário: Adolescente
Adulto
Fatores Etários
Canadá
Feminino
Seres Humanos
Infertilidade Masculina/fisiopatologia
Modelos Logísticos
Masculino
Cadeias de Markov
Meia-Idade
Método de Monte Carlo
Análise Multivariada
Neoplasias/diagnóstico
Razão de Chances
Percepção
Estudos Prospectivos
Radioterapia/efeitos adversos
Inquéritos e Questionários
Resultado do Tratamento
Estados Unidos
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; MULTICENTER STUDY; OBSERVATIONAL STUDY
[Nm] Nome de substância:
0 (Antineoplastic Agents)
[Em] Mês de entrada:1712
[Cu] Atualização por classe:180207
[Lr] Data última revisão:
180207
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171206
[Cl] Clinical Trial:ClinicalTrial
[St] Status:MEDLINE


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[PMID]:28974309
[Au] Autor:Feinberg EC
[Ad] Endereço:Northwestern University Feinberg School of Medicine, Chicago, Illinois.
[Ti] Título:Advances in cryopreservation: we are not frozen in time.
[So] Source:Fertil Steril;108(5):763, 2017 Nov.
[Is] ISSN:1556-5653
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Life is like riding a bicycle, to keep your balance you must keep moving. -Albert Einstein.
[Mh] Termos MeSH primário: Criopreservação/tendências
Infertilidade/terapia
Técnicas de Reprodução Assistida/tendências
Bancos de Esperma/tendências
Espermatozoides
[Mh] Termos MeSH secundário: Criopreservação/ética
Criopreservação/história
Difusão de Inovações
Feminino
Fertilidade
Previsões
História do Século XX
História do Século XXI
Seres Humanos
Infertilidade/diagnóstico
Infertilidade/fisiopatologia
Masculino
Gravidez
Técnicas de Reprodução Assistida/ética
Técnicas de Reprodução Assistida/história
Bancos de Esperma/ética
Bancos de Esperma/história
[Pt] Tipo de publicação:EDITORIAL; HISTORICAL ARTICLE
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171113
[Lr] Data última revisão:
171113
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171005
[St] Status:MEDLINE


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[PMID]:27887716
[Au] Autor:Scheib JE; Ruby A; Benward J
[Ad] Endereço:Department of Psychology, University of California, Davis, California; The Sperm Bank of California, Berkeley, California. Electronic address: jescheib@ucdavis.edu.
[Ti] Título:Who requests their sperm donor's identity? The first ten years of information releases to adults with open-identity donors.
[So] Source:Fertil Steril;107(2):483-493, 2017 Feb.
[Is] ISSN:1556-5653
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To report findings from 10 years of requests from adults eligible to obtain their open-identity sperm donor's information. DESIGN: Analysis of archived family and donor data. Semistructured interviews at information releases. SETTING: Not applicable. PATIENT(S): A total of 85 DI adults requesting 43 donor identities; program data on 256 DI families. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): We identified [1] demographic predictors of requesting donor identities, [2] information release timing and length, and [3] request motives. RESULT(S): Just >35% of eligible DI adults requested their donor's identity. Adults ranged from 18-27 years, requesting at median age 18 years. More women than men requested. Proportionally fewer adults requested when they had heterosexual-couple parents, and proportionally more when they had one rather than two parents. In interviews, the common theme was wanting to know more about the donor, especially about shared characteristics. Most adults planned to contact their donor. More than 94% of adults had donors who were open to contact; adults expressed modest expectations about this contact. CONCLUSION(S): In 2001, the first adults became eligible to obtain their open-identity sperm donor's information. Ten years of identity requests at one program indicates that information about one's donor is important to a significant proportion of these DI adults. Most requested their donor's identity soon after becoming eligible, suggesting some urgency to wanting the information. Interview data highlighted the role of donor information in helping adults better understand themselves and their ancestry. Findings hold important implications for practice and policy.
[Mh] Termos MeSH primário: Crianças Adultas/psicologia
Disseminação de Informação
Doadores Vivos/psicologia
Técnicas de Reprodução Assistida/psicologia
Espermatozoides
Doadores de Tecidos/psicologia
Revelação da Verdade
Doadores não Relacionados/psicologia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Fatores Etários
California
Características da Família
Feminino
Hereditariedade
Seres Humanos
Nascimento Vivo
Masculino
Motivação
Linhagem
Fatores Sexuais
Bancos de Esperma
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170613
[Lr] Data última revisão:
170613
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161127
[St] Status:MEDLINE


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[PMID]:27807913
[Au] Autor:Chatdarong K
[Ad] Endereço:Department of Obstetrics, Gynaecology and Reproduction, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, Thailand.
[Ti] Título:Retained fertilizing capability in cryopreserved feline spermatozoa.
[So] Source:Reprod Domest Anim;52 Suppl 2:261-264, 2017 Apr.
[Is] ISSN:1439-0531
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:Sperm cryopreservation offers a long-term preservation of male genetic materials for future assisted reproductive technologies. However, dramatic changes in temperature during freezing and thawing injure sperm cells. While motility is essential for AI and membrane integrity is crucial for in vitro fertilization (IVF), sperm DNA integrity is a common index of fertilizing capability required for AI, IVF and intracytoplasmic sperm injection (ICSI). In endangered felids died unexpectedly, attempts have been made to recover as many DNA intact spermatozoa as possible from epididymis and testis to increase the opportunity to produce offspring in future. Although sperm from caudal epididymis has shown retained fertilizing capability after freezing and thawing (27.3% conception rate after unilateral intrauterine insemination), sperm recovery from the corpus epididymis has been suggested as an alternative to increase the amount of preserved genetic materials. To improve epididymal sperm quality, pre-treatment with single-layer centrifugation resulted in selection of sperm cells with intact DNA while post-thaw treatment with extracellular ATP incubation promoted the blastocyst rate. Cold storage of domestic cat testis for 7 days at 4°C demonstrated <1% of sperm cells with fragmented DNA. Moreover, isolated testicular sperm cells, stored for 7 days at 4°C, produced after ICSI poorer percentages of cleavage, morula and blastocyst than the fresh control. In wild felids, a death-to-necropsy time of 2 hr after a jungle cat (Felis chaus) aged 10 years died during anaesthesia plus another necropsy-to-sperm recovery time of 25 hr has been reported to yield the post-thawed testicular sperm with 22.2% intact DNA. In summary, the chromatin structure of feline ejaculated and epididymal sperm seems to be tolerated to cold storage and cryopreservation; thus, fertilizing capability is well protected. In contrast, the cat testicular sperm DNA is generally damaged through the cryopreservation.
[Mh] Termos MeSH primário: Gatos
Criopreservação/veterinária
Fertilização In Vitro/veterinária
Preservação do Sêmen/veterinária
Espermatozoides/fisiologia
[Mh] Termos MeSH secundário: Animais
Conservação dos Recursos Naturais
DNA/análise
Espécies em Perigo de Extinção
Epididimo/citologia
Felidae/genética
Fertilização
Masculino
Preservação do Sêmen/métodos
Bancos de Esperma
Injeções de Esperma Intracitoplásmicas/veterinária
Espermatozoides/química
Espermatozoides/ultraestrutura
Testículo/citologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
9007-49-2 (DNA)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170906
[Lr] Data última revisão:
170906
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161104
[St] Status:MEDLINE
[do] DOI:10.1111/rda.12855


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[PMID]:27807883
[Au] Autor:Swanson WF; Bateman HL; Vansandt LM
[Ad] Endereço:Cincinnati Zoo & Botanical Garden, Center for Conservation and Research of Endangered Wildlife, 3400 Vine Street, Cincinnati OH USA.
[Ti] Título:Urethral catheterization and sperm vitrification for simplified semen banking in felids.
[So] Source:Reprod Domest Anim;52 Suppl 2:255-260, 2017 Apr.
[Is] ISSN:1439-0531
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:Semen banking of domestic cats and wild felids represents a vital resource for their long-term conservation, but current methods require access to advanced training and specialized equipment. A newer method of semen collection, urethral catheterization of medetomidine-treated cats, allows recovery of high sperm numbers, but it is unclear if this approach permits maximal sperm recovery or is feasible using less expensive alpha-2 agonists. Similarly, a newer sperm preservation approach, vitrification, offers advantages of simplicity and minimal equipment needs, but its efficacy in combination with urethral catheterization has not been investigated. Our specific objectives were to (i) evaluate sequential semen recovery with urethral catheterization and electroejaculation in domestic cats, (ii) assess the effectiveness of a weak (xylazine) versus strong (dexmedetomidine) alpha-2 agonist for inducing sperm release, and (iii) compare post-thaw sperm motility, acrosome status and fertilizing capacity of catheter-recovered samples after vitrification or straw freezing. Results indicated that electroejaculation following repeated catheterization allowed recovery of additional spermatozoa (range, 11-32 × 10  sperm/male) and that xylazine was ineffective for inducing meaningful sperm release (range, 0-0.4 × 10 sperm/male). Post-thaw motility and acrosome status of vitrified catheter samples did not differ (p > .05) from that of straw frozen samples. Preliminary results indicated that in vitro fertilization success (9/30, 30%) of vitrified catheter sperm did not differ (p > .05) from that observed with straw frozen samples (17/30, 57%). In conclusion, urethral catheterization of dexmedetomidine-treated cats allows recovery of substantial sperm numbers but electroejaculation still may be warranted for maximal sperm recovery. Xylazine is not suitable as an inexpensive alternative to dexmedetomidine for catheterization. Vitrification of catheter samples results in comparable post-thaw parameters to straw freezing and may be adequate for use with oviductal insemination procedures.
[Mh] Termos MeSH primário: Gatos
Criopreservação/veterinária
Felidae
Preservação do Sêmen/veterinária
Bancos de Esperma/métodos
Cateterismo Urinário/veterinária
[Mh] Termos MeSH secundário: Acrossomo
Agonistas de Receptores Adrenérgicos alfa 2
Animais
Dexmedetomidina/administração & dosagem
Ejaculação
Estimulação Elétrica
Fertilização In Vitro/veterinária
Temperatura Alta
Masculino
Preservação do Sêmen/métodos
Manejo de Espécimes/métodos
Manejo de Espécimes/veterinária
Contagem de Espermatozoides/veterinária
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Adrenergic alpha-2 Receptor Agonists); 67VB76HONO (Dexmedetomidine)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170906
[Lr] Data última revisão:
170906
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161104
[St] Status:MEDLINE
[do] DOI:10.1111/rda.12863


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[PMID]:27793371
[Au] Autor:Huang C; Li B; Xu K; Liu D; Hu J; Yang Y; Nie H; Fan L; Zhu W
[Ad] Endereço:Institute of Reproductive and Stem Cell Engineering, Basic Medicine College, Central South University, Changsha, Hunan, People's Republic of China.
[Ti] Título:Decline in semen quality among 30,636 young Chinese men from 2001 to 2015.
[So] Source:Fertil Steril;107(1):83-88.e2, 2017 Jan.
[Is] ISSN:1556-5653
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To provide information of semen quality among young Chinese men in the past 15 years. DESIGN: Retrospective cross-sectional study. SETTING: Sperm bank. PATIENT(S): A total of 30,636 young adult men who applied to be sperm donors at the Hunan Province Human Sperm Bank of China in 2001-2015 were included in the study. INTERVENTION(S): Physical examination and analysis of blood and semen samples. MAIN OUTCOME MEASURE(S): Semen parameters, such as semen volume, sperm concentration, total sperm count, progressively motile sperm count, sperm progressive motility, sperm morphology, and round cells. RESULT(S): Many of the semen parameters showed a decreasing trend over the 15-year observation period. The sperm concentration and percentage of sperm with normal morphology decreased from 68 × 10 /mL to 47 × 10 /mL and from 31.8% to 10.8%, respectively. Although sperm progressive motility showed irregular variation, the progressively motile sperm count decreased from 34 × 10 to 21 × 10 over the 15-year period. Furthermore, the rate of qualified donors fell from 55.78% in 2001 to 17.80% in 2015, and the rate for 2015 was approximately threefold lower than the corresponding rates in 2001. CONCLUSION(S): The semen quality among young Chinese men has declined over a period of 15 years, especially in terms of sperm concentration, total sperm count, sperm progressive motility, and normal morphology.
[Mh] Termos MeSH primário: Grupo com Ancestrais do Continente Asiático
Análise do Sêmen
Espermatozoides/patologia
Doadores de Tecidos
[Mh] Termos MeSH secundário: Adulto
Fatores Etários
Forma Celular
China
Estudos Transversais
Seres Humanos
Masculino
Estudos Retrospectivos
Bancos de Esperma
Contagem de Espermatozoides
Motilidade Espermática
Fatores de Tempo
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170714
[Lr] Data última revisão:
170714
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161030
[St] Status:MEDLINE


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[PMID]:27621105
[Au] Autor:DiNofia AM; Wang X; Yannekis G; Ogle S; Hobbie WL; Carlson CA; Ginsberg JP
[Ad] Endereço:Division of Oncology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
[Ti] Título:Analysis of semen parameters in a young cohort of cancer patients.
[So] Source:Pediatr Blood Cancer;64(2):381-386, 2017 Feb.
[Is] ISSN:1545-5017
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Infertility can be the result of some common cancer treatments and can significantly impact quality of life. Semen cryopreservation allows for fertility preservation. We analyzed the semen parameters of specimens collected from pubertal males from the Children's Hospital of Philadelphia (CHOP) in order to expand current knowledge on the quality of these specimens and inform a standard clinical practice. PROCEDURE: Males who were at least Tanner stage III and newly diagnosed with cancer at CHOP were approached regarding sperm banking. The success and quality of the samples collected were analyzed and compared in relation to prior treatment, age, and diagnosis. RESULTS: From 399 patients approached for semen collection, 339 (85%) attempted to bank sperm, of which 265 (78%) were successful and 60 (15%) refused to participate. Therapy prior to sperm banking significantly impacted a successful collection (P < 0.01). Only 16.9% of the untreated patients were azoospermic, whereas 84.0% of the treated subjects were azoospermic. Older patients were less likely to be azoospermic and have a greater quality collection when compared with younger patients (P < 0.01). However, 65% of our youngest patients still were able to cryopreserve semen. There was no difference in azoospermia across diagnostic groups (P = 0.35), though there were differences in quality of semen parameters across diagnoses. CONCLUSION: Our data support that sperm banking pubertal males prior to the initiation of therapy is feasible. While there were differences in quality of semen parameters across age and diagnostic groups, most males, regardless of age or diagnosis, had adequate specimens for cryopreservation.
[Mh] Termos MeSH primário: Preservação da Fertilidade
Infertilidade Masculina/prevenção & controle
Neoplasias/complicações
Preservação do Sêmen
Sêmen/química
[Mh] Termos MeSH secundário: Adolescente
Criopreservação
Seguimentos
Seres Humanos
Infertilidade Masculina/etiologia
Masculino
Neoplasias/patologia
Neoplasias/terapia
Prognóstico
Estudos Retrospectivos
Bancos de Esperma
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170621
[Lr] Data última revisão:
170621
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160914
[St] Status:MEDLINE
[do] DOI:10.1002/pbc.26221


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[PMID]:27565252
[Au] Autor:Isley L; Falk RE; Shamonki J; Sims CA; Callum P
[Ad] Endereço:California Cryobank, Los Angeles, California.
[Ti] Título:Management of the risks for inherited disease in donor-conceived offspring.
[So] Source:Fertil Steril;106(6):1479-1484, 2016 Nov.
[Is] ISSN:1556-5653
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To illustrate the burden of inherited disease on donor-conceived offspring based on mode of inheritance and to provide guidance on methods of risk reduction. DESIGN: An 8.5-year retrospective review of outcome reports and donor management to summarize medical risks to donor-conceived offspring that presented after the sperm donors were qualified for participation in the donor program. SETTING: Not applicable. PATIENT(S): None. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Description of our experience with newly identified medical risks in donor-conceived offspring as well as how this information was ascertained and managed. RESULT(S): More than half of the indications to restrict donor specimen distribution were due to multifactorial disorders. Approximately one third of the restrictions involved autosomal recessive disorders. The remainder of the restrictions were due to the other indications, including autosomal dominant disorders. CONCLUSION(S): The risks for multifactorial disorders or undiagnosed autosomal dominant disease cannot be significantly reduced or eliminated with routine donor screening procedures. Ongoing risk assessment is essential to identify new genetic risks for autosomal dominant and multifactorial disorders. These assessments require an investment of resources and genetics professionals in the long-term management of changing health information as well as collaboration among gamete facilities, recipients, donors, and their health care providers.
[Mh] Termos MeSH primário: Doenças Genéticas Inatas/genética
Doenças Genéticas Inatas/prevenção & controle
Doadores Vivos
Técnicas de Reprodução Assistida/efeitos adversos
Sêmen
Doadores não Relacionados
[Mh] Termos MeSH secundário: Feminino
Doenças Genéticas Inatas/diagnóstico
Predisposição Genética para Doença
Testes Genéticos
Hereditariedade
Heterozigoto
Seres Humanos
Masculino
Linhagem
Gravidez
Estudos Retrospectivos
Medição de Risco
Fatores de Risco
Gestão de Riscos
Bancos de Esperma
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170605
[Lr] Data última revisão:
170605
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160828
[St] Status:MEDLINE


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[PMID]:27281951
[Au] Autor:Nau JY
[Ti] Título:[Not Available].
[Ti] Título:MISCELLANÉES SPERMATIQUES ET VIROLOGIQUES, CUTANÉES ET ÉTHIQUES..
[So] Source:Rev Med Suisse;12(516):862-3, 2016 Apr 27.
[Is] ISSN:1660-9379
[Cp] País de publicação:Switzerland
[La] Idioma:fre
[Mh] Termos MeSH primário: Inseminação Artificial/legislação & jurisprudência
Pele/anatomia & histologia
Bancos de Esperma/legislação & jurisprudência
Infecção pelo Zika virus/complicações
[Mh] Termos MeSH secundário: Feminino
Seres Humanos
Microcefalia/virologia
Gravidez
Complicações Infecciosas na Gravidez/virologia
Impressão Tridimensional
Bancos de Esperma/normas
Doadores de Tecidos/legislação & jurisprudência
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1606
[Cu] Atualização por classe:160610
[Lr] Data última revisão:
160610
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160611
[St] Status:MEDLINE


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[PMID]:27156003
[Au] Autor:Ferrari S; Paffoni A; Filippi F; Busnelli A; Vegetti W; Somigliana E
[Ad] Endereço:Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Infertility Unit, via M. Fanti 6, 20122 Milan, Italy.
[Ti] Título:Sperm cryopreservation and reproductive outcome in male cancer patients: a systematic review.
[So] Source:Reprod Biomed Online;33(1):29-38, 2016 Jul.
[Is] ISSN:1472-6491
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:This systematic review of the literature reports on the use and effectiveness of sperm banking programmes for cancer patients. Thirty studies with 11798 patients were included. The aggregated rate of use of cryopreserved semen was 8% (95% CI 8 to 9%). A statistically significant correlation emerged between the mean and median duration of follow-up and the rate of use (R(2) = 0.46; P = 0.03). The rate of patients discarding their frozen sample was reported in 11 studies. The aggregated rate was 16% (95% CI 15 to 17%). The rate of patients who used their frozen semen and achieved parenthood was reported in 19 papers. The aggregated rate was 49% (95% CI 44 to 53%). The rate of patients achieving parenthood with the use of frozen sperm is low and, from an economical perspective, the effectiveness of programmes of sperm banking might therefore be questioned. On the other hand, the low rate of patients discarding their frozen samples and the correlation between rate of use and duration of follow-up suggest that the calculated 8% rate of use may be an under-estimation and that cumulative rate of use may be substantially higher. Specific studies are, however, required to clarify this issue.
[Mh] Termos MeSH primário: Criopreservação
Neoplasias/complicações
Preservação do Sêmen
[Mh] Termos MeSH secundário: Adolescente
Adulto
Coeficiente de Natalidade
Feminino
Seres Humanos
Infertilidade Masculina/prevenção & controle
Masculino
Meia-Idade
Neoplasias/fisiopatologia
Gravidez
Taxa de Gravidez
Reprodução
Sêmen
Bancos de Esperma
Espermatozoides/patologia
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170407
[Lr] Data última revisão:
170407
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