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Pesquisa : N02.278.065.900.205 [Categoria DeCS]
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[PMID]:29049290
[Au] Autor:Fu SH; Liu JY; Huang CC; Lin FL; Yang RS; Hou CH
[Ad] Endereço:Department of Orthopedics, National Taiwan University Hospital Yun-Lin Branch, Yun-Lin County, Taiwan.
[Ti] Título:Quality control processes in allografting: A twenty-year retrospective review of a hospital-based bone bank in Taiwan.
[So] Source:PLoS One;12(10):e0184809, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Musculoskeletal allografts are now commonly used. To decrease the potential risks of transmission of pathogenic bacteria, fungi, or viruses to the transplant recipients, certain issues regarding the management of patients who receive contaminated allografts need to be addressed. We aimed to clarify the incidence and extent of disease transmission from allografts by analyzing the allografting procedures performed in the bone bank of our hospital over the past 20 years. We retrospectively reviewed the data from our allograft registry center on 3979 allografts that were implanted in 3193 recipients throughout a period of two decades, from July 1991 to June 2011. The source of the allografts, results of all screening tests, dates of harvesting and implantation, and recipients of all allografts were checked. With the help of the Center for Infection Control of our hospital, a strict prospective, hospital-wide, on-site surveillance was conducted, and every patient with healthcare-associated infection was identified. Fisher's exact test was used to compare the infection rate between recipients with sterile allografts and those with contaminated allografts. The overall discard and infection rates were, respectively, 23% and 1.3% in the first decade (1991-2001); and 18.4% and 1.25% in the second decade (2001-2011). The infection rate of contaminated allograft recipients was significantly higher than that of sterile allograft recipients (10% vs. 1.15%, P < 0.01) in the second decade. Both infection and discard rates of our bone bank are comparable with those of international bone banks. Strict allograft processing and adequate prophylactic use of antibiotics are critical to prevent infection and disease transmission in such cases.
[Mh] Termos MeSH primário: Aloenxertos
Bancos de Ossos
Hospitais
Controle de Qualidade
[Mh] Termos MeSH secundário: Adulto
Idoso
Idoso de 80 Anos ou mais
Feminino
Seres Humanos
Masculino
Meia-Idade
Estudos Retrospectivos
Taiwan
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171107
[Lr] Data última revisão:
171107
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171020
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0184809


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[PMID]:27631324
[Au] Autor:Qiu L; Zhang Y; Zhang Q; Xu L; Niu X; Zhang L
[Ad] Endereço:Department of Electronic Engineering, Tsinghua University, Beijing, 100084, China. eeqiulei@gmail.com.
[Ti] Título:Allograft selection for distal femur through cutting contour registration.
[So] Source:Cell Tissue Bank;17(4):699-711, 2016 Dec.
[Is] ISSN:1573-6814
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Allograft reconstruction is an acceptable procedure for the recovery of normal anatomy after the bone tumor resection. During the past few years, several automated methods have been proposed to select the best anatomically matching allograft from the virtual donor bone bank. The surface-based automated method uses the contralateral healthy bone to obtain the normal surface shape of the diseased bone, which could achieve good matching of the defect and the selected allograft. However, the surface-based method focuses on the matching of the whole bone so that the matching of the contact surface between the allograft and the recipient bone may not be optimal. To deal with the above problem, we propose a cutting contour based method for the allograft selection. Cutting contour from the recipient bone could reflect the structural information of the defect and is seldom influenced by tumor. Thus the cutting contour can be used as the matching template to find the optimal alignment of the recipient bone and the allograft. The proposed method is validated using the data of distal femurs where bone transplantation is commonly performed. Experimental results show that the proposed method generally outperforms the surface-based method within modest extra time. Overall, our contour-based method is an effective complementary technique for allograft selection in the virtual bone bank.
[Mh] Termos MeSH primário: Aloenxertos/anatomia & histologia
Bancos de Ossos
Transplante Ósseo
Fêmur/anatomia & histologia
Imagem Tridimensional/métodos
[Mh] Termos MeSH secundário: Transplante Ósseo/métodos
Fêmur/transplante
Seres Humanos
Modelos Anatômicos
Software
Transplante Homólogo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170208
[Lr] Data última revisão:
170208
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160916
[St] Status:MEDLINE


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[PMID]:26910111
[Au] Autor:Man WY; Monni T; Jenkins R; Roberts P
[Ad] Endereço:The Royal Gwent Hospital, Lovely Lane, Newport, NP20 2UB, UK. wingyum@gmail.com.
[Ti] Título:Post-operative infection with fresh frozen allograft: reported outcomes of a hospital-based bone bank over 14 years.
[So] Source:Cell Tissue Bank;17(2):269-75, 2016 Jun.
[Is] ISSN:1573-6814
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Femoral head bone allografts have traditionally been used to provide mechanical stability to areas of bony deficiency, or for its osteoinductive and osteoconductive properties. Concerns have been raised over increased infection rates following the use of fresh-frozen graft tissue. This retrospective study aims to investigate the outcomes of fresh frozen femoral heads kept in a regulated, non-commercial bone bank at a university teaching hospital.The local bone bank database was used to identify released femoral heads during a 14 year study period (September 1999-December 2013) whereby a retrospective review of patient records was undertaken to determine clinical outcome. During the observed study period, 427 femoral heads were released from cold storage. Of these, 270 femoral heads had a mean follow-up of 347 days. 157 femoral heads were excluded due to insufficient follow-up data (n = 132) or discarded due to breaks in the cold chain prior to use (n = 25). Of the 270 included femoral heads, 231 (85.6 %) had no reported complications with good graft incorporation. In the remaining 39 with reported complications, only 5 (2.6 %) developed a postoperative infection. Our findings suggest that the use of fresh frozen allograft does not materially increase the risk of post-operative bacterial infection. Our reported post-operative infection rates are comparable with infection rates of other similar studies on fresh frozen allograft use.
[Mh] Termos MeSH primário: Aloenxertos/transplante
Bancos de Ossos
Transplante Ósseo/efeitos adversos
Criopreservação
Hospitais
Complicações Pós-Operatórias/etiologia
Complicações Pós-Operatórias/microbiologia
[Mh] Termos MeSH secundário: Idoso
Idoso de 80 Anos ou mais
Feminino
Cabeça do Fêmur/transplante
Seres Humanos
Masculino
Meia-Idade
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170206
[Lr] Data última revisão:
170206
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160225
[St] Status:MEDLINE
[do] DOI:10.1007/s10561-016-9547-8


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[PMID]:26138308
[Au] Autor:Warnock JM; Rowan CH; Davidson H; Millar C; McAlinden MG
[Ad] Endereço:Musgrave Park Bone Bank, Belfast, UK. jmwarnock@doctors.org.uk.
[Ti] Título:Improving efficiency of a regional stand alone bone bank.
[So] Source:Cell Tissue Bank;17(1):85-90, 2016 Mar.
[Is] ISSN:1573-6814
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:The introduction of a stand-alone Bone Bank in our Regional Orthopaedic Hospital has improved the availability of femoral head allograft. Benninger et al. (Bone Joint J 96-B:1307-1311, 2014), demonstrated their institutions bank to be cost effective despite a 30 % discard rate for harvested allograft. We sought to audit our own discard rates and subsequent cost-effectiveness of our bone bank. Donor recruitment. Before approaching a potential donor, our establishment's nurse specialists review their clinical notes and biochemical laboratory results, available on a regional Electronic Care Records. They view femoral head architecture on radiographs against set criteria, Patient Archive and Communication system (SECTRA, Sweden). In total 1383 femoral heads were harvested, 247 were discarded giving an overall rate of 17.9 %. The most common reasons for discard of harvested graft was a positive microbiology/bacteriology result, n = 96 (38.9 %). After a rise in discard rates in 2007, we have steadily reduced our discard rates since 2006/2007 (28.2 %), 2008/2009 (17 %), 2010/2011 (14.8 %), and finally to 10.3 % in 2012/2013. In the current financial year, our cost to harvest, test, store and release a femoral head is £ 610. With a structured donor recruitment process and unique pre-operative radiographic analysis we have successfully reduced our discard rates bi-annually making our bone bank increasingly cost-effective.
[Mh] Termos MeSH primário: Bancos de Ossos/normas
[Mh] Termos MeSH secundário: Bactérias/isolamento & purificação
Custos e Análise de Custo
Cabeça do Fêmur/diagnóstico por imagem
Seres Humanos
Doadores de Tecidos
Coleta de Tecidos e Órgãos/economia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1612
[Cu] Atualização por classe:161230
[Lr] Data última revisão:
161230
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150704
[St] Status:MEDLINE
[do] DOI:10.1007/s10561-015-9523-8


  5 / 145 MEDLINE  
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[PMID]:25814343
[Au] Autor:Hovanyecz P; Lorenti A; Lucero JM; Gorla A; Castiglioni AE
[Ad] Endereço:, Rosario, Santa Fe, Argentina.
[Ti] Título:Living donor bone banking: processing and discarding--from procurement to therapeutic use.
[So] Source:Cell Tissue Bank;16(4):593-603, 2015 Dec.
[Is] ISSN:1573-6814
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Skeletal muscle and osteoarticular tissue banks are responsible to procure, process, store and distribute tissues, from living and cadaveric donors. The procedures involve the application of protocols covering all aspects of the banking, ensuring the best tissue quality and maximum safety for the recipient. An analysis on the causes of bone tissue discarded by Biotar Tissue Bank between January 2005 and December 2012 was carried. Bone tissue was obtained from both hip and knee replacement (femoral heads and tibial plateau respectively) in living donors treated at different medical-surgical institutions in Argentina. These tissues were processed at the Bank to produce both frozen and lyophilized cancellous bone. Out of 3413 donated bones received by the Bank, 77.55 % resulted in final product, while the remaining 22.44 % was discarded in compliance with the quality standards of both the Bank and the regulatory authority. Comparing the last and the first year of the studied period, the number of discarded tissue increased 3.6 times, while the number of collected bones was approximately 10 times higher. Related to total disposed tissue, reactive serology was the most frequent cause (62.14 %), followed by inappropriate collection/storage of blood sample (30.81 %). A progressive reduction in the percentages of total discard was observed, and this was proportional to inappropriate collection/storage of blood sample. No significant differences were found in the discard rates due to positive serology throughout all the years studied. The success of a tissue bank requires full commitment of all the personnel especially the team members responsible for donor selection and the processing of allografts. It is important to critically screen donors in the early stages of donor recruitment. All of the procedures carried out by the tissue bank are parts of the quality control system which must be strictly carried out. Biotar Tissue Bank is continuously committed to ensure safety to the recipients.
[Mh] Termos MeSH primário: Bancos de Ossos/estatística & dados numéricos
Transplante Ósseo/estatística & dados numéricos
Seleção do Doador/estatística & dados numéricos
Doadores Vivos/estatística & dados numéricos
Obtenção de Tecidos e Órgãos/estatística & dados numéricos
[Mh] Termos MeSH secundário: Adulto
Idoso
Idoso de 80 Anos ou mais
Argentina
Feminino
Seres Humanos
Masculino
Meia-Idade
Preservação de Órgãos/estatística & dados numéricos
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1609
[Cu] Atualização por classe:151126
[Lr] Data última revisão:
151126
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150328
[St] Status:MEDLINE
[do] DOI:10.1007/s10561-015-9507-8


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[PMID]:25775919
[Au] Autor:Weiss E
[Ad] Endereço:Department of Anthropology, San Jose State University, San Jose, California, USA.
[Ti] Título:Can we create ethnically diverse skeletal collection from donated bodies?
[So] Source:Anthropol Anz;72(1):43-53, 2015.
[Is] ISSN:0003-5548
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:Understanding bone health is least invasively and most effectively done through studying skeletal remains that reflect the living populations who will benefit from the knowledge produced through research. Donated body collections that accurately represent modern populations are needed for osteological insights to be applied to clinical practices. However, even though the US is growing increasingly diverse, donated body collections still suffer from a lack of ethnic diversity. Most individuals who donate their whole-bodies after death are European-American. Reasons for a lack of ethnic diversity stem from past injustices and present religious norms. Increasing body donation among minorities in the US and abroad may be difficult.
[Mh] Termos MeSH primário: Antropologia Física/métodos
Bancos de Ossos
Grupos Étnicos
Grupo com Ancestrais do Continente Europeu
Doadores de Tecidos
[Mh] Termos MeSH secundário: Seres Humanos
Religião
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1510
[Cu] Atualização por classe:150317
[Lr] Data última revisão:
150317
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150318
[St] Status:MEDLINE
[do] DOI:10.1127/anthranz/2014/0433


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[PMID]:25772276
[Au] Autor:Wu Z; Fu J; Wang Z; Li X; Li J; Pei Y; Pei G; Li D; Guo Z; Fan H
[Ad] Endereço:Department of Orthopaedic Surgery, Xi-Jing Hospital, The Fourth Military Medical University, Xi'an, 710032, China.
[Ti] Título:Three-dimensional virtual bone bank system for selecting massive bone allograft in orthopaedic oncology.
[So] Source:Int Orthop;39(6):1151-8, 2015 Jun.
[Is] ISSN:1432-5195
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:PURPOSE: Although structural bone allografts have been used for years to treat large defects caused by tumour or trauma, selecting the most appropriate allograft is still challenging. The objectives of this study were to: (1) describe the establishment of a visual bone bank system and workflow of allograft selection, and (2) show mid-term follow-up results of patients after allograft implantation. METHODS: Allografts were scanned and stored in Digital Imaging and Communications in Medicine (DICOM) files. Then, image segmentation was conducted and 3D model reconstructed to establish a visual bone bank system. Based on the volume registration method, allografts were selected after a careful matching process. From November 2010 to June 2013, with the help of the Computer-assisted Orthopaedic Surgery (CAOS) navigation system, the allografts were implanted in 14 patients to fill defects after tumour resection. RESULTS: By combining the virtual bone bank and CAOS, selection time was reduced and matching accuracy was increased. After 27.5 months of follow-up, the mean Musculoskeletal Tumor Society (MSTS) 93 functional score was 25.7 ± 1.1 points. Except for two patients with pulmonary metastases, 12 patents were alive without evidence of disease at the time this report was written. CONCLUSIONS: The virtual bone bank system was helpful for allograft selection, tumour excision and bone reconstruction, thereby improving the safety and effectiveness of limb-salvage surgery.
[Mh] Termos MeSH primário: Bancos de Ossos/organização & administração
Neoplasias Ósseas/cirurgia
Transplante Ósseo
Processamento de Imagem Assistida por Computador/métodos
Salvamento de Membro
[Mh] Termos MeSH secundário: Aloenxertos
Feminino
Seres Humanos
Imagem Tridimensional
Salvamento de Membro/métodos
Masculino
Meia-Idade
Procedimentos Cirúrgicos Reconstrutivos/métodos
Cirurgia Assistida por Computador
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1602
[Cu] Atualização por classe:170924
[Lr] Data última revisão:
170924
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150317
[St] Status:MEDLINE
[do] DOI:10.1007/s00264-015-2719-5


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[PMID]:25720358
[Au] Autor:Hernigou P
[Ad] Endereço:Orthopaedic Surgery, Hopital Henri Mondor, Paris, France, philippe.hernigou@wanadoo.fr.
[Ti] Título:Bone transplantation and tissue engineering, part III: allografts, bone grafting and bone banking in the twentieth century.
[So] Source:Int Orthop;39(3):577-87, 2015 Mar.
[Is] ISSN:1432-5195
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:During the 20th century, allograft implantation waned in popularity as a clinical activity. Reports appeared in the literature describing several small series of patients in whom bone was obtained from amputation specimens or recently deceased individuals. The concept of bone banking became a reality during and after World War II when the National Naval Tissue Bank was established in Bethesda and a number of small banks sprang up in hospitals throughout the world. Small fragments, either of cortical or medullary bone, from these banks were used heterotopically to augment spinal fusions, to implant into cyst cavities, or to serve as a scaffolding for repair of non- or delayed union of fractures of the long bones.
[Mh] Termos MeSH primário: Bancos de Ossos/história
Transplante Ósseo/história
Ortopedia/história
Engenharia Tecidual/história
[Mh] Termos MeSH secundário: Aloenxertos
História do Século XX
Seres Humanos
Procedimentos Ortopédicos/história
Transplante Homólogo
[Pt] Tipo de publicação:HISTORICAL ARTICLE; JOURNAL ARTICLE
[Em] Mês de entrada:1602
[Cu] Atualização por classe:170924
[Lr] Data última revisão:
170924
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150228
[St] Status:MEDLINE
[do] DOI:10.1007/s00264-015-2669-y


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[PMID]:25687771
[Au] Autor:Ramalingam S; Mohd S; Samsuddin SM; Min NG; Yusof N; Mansor A
[Ad] Endereço:UMMC Bone Bank, Department of Orthopaedic Surgery, Faculty of Medicine, National Orthopaedic Centre of Excellence in Research and Learning (NOCERAL), University of Malaya, 50603, Kuala Lumpur, Malaysia. sit_sarav@yahoo.com.
[Ti] Título:A retrospective study on annual evaluation of radiation processing for frozen bone allografts complying to quality system requirements.
[So] Source:Cell Tissue Bank;16(4):545-52, 2015 Dec.
[Is] ISSN:1573-6814
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Bone allografts have been used widely to fill up essential void in orthopaedic surgeries. The benefit of using allografts to replace and reconstruct musculoskeletal injuries, fractures or disease has obtained overwhelming acceptance from orthopaedic surgeons worldwide. However, bacterial infection and disease transmission through bone allograft transplantation have always been a significant issue. Sterilization by radiation is an effective method to eliminate unwanted microorganisms thus assist in preventing life threatening allograft associated infections. Femoral heads procured from living donors and long bones (femur and tibia) procured from cadaveric donors were sterilized at 25 kGy in compliance with international standard ISO 11137. According to quality requirements, all records of bone banking were evaluated annually. This retrospective study was carried out on annual evaluation of radiation records from 1998 until 2012. The minimum doses absorbed by the bones were ranging from 25.3 to 38.2 kGy while the absorbed maximum doses were from 25.4 to 42.3 kGy. All the bones supplied by our UMMC Bone Bank were sterile at the required minimum dose of 25 kGy. Our analysis on dose variation showed that the dose uniformity ratios in 37 irradiated boxes of 31 radiation batches were in the range of 1.003-1.251, which indicated the doses were well distributed.
[Mh] Termos MeSH primário: Bancos de Ossos/normas
Transplante Ósseo/normas
Osso e Ossos/microbiologia
Osso e Ossos/efeitos da radiação
Criopreservação/normas
Esterilização/normas
[Mh] Termos MeSH secundário: Aloenxertos/normas
Bactérias/efeitos da radiação
Bancos de Ossos/estatística & dados numéricos
Transplante Ósseo/estatística & dados numéricos
Criopreservação/métodos
Criopreservação/estatística & dados numéricos
Relação Dose-Resposta à Radiação
Raios gama
Fidelidade a Diretrizes
Seres Humanos
Malásia
Auditoria Médica
Guias de Prática Clínica como Assunto
Dose de Radiação
Estudos Retrospectivos
Esterilização/estatística & dados numéricos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1609
[Cu] Atualização por classe:151126
[Lr] Data última revisão:
151126
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150218
[St] Status:MEDLINE
[do] DOI:10.1007/s10561-015-9501-1


  10 / 145 MEDLINE  
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[PMID]:25656787
[Au] Autor:Mohd S; Samsuddin SM; Ramalingam S; Min NW; Yusof N; Zaman TK; Mansor A
[Ad] Endereço:UMMC Bone Bank, National Orthopaedic Centre of Excellence in Research and Learning (NOCERAL), Department of Orthopaedic Surgery, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia. suhailimohd@ummc.edu.my.
[Ti] Título:Assessing bone banking activities at University of Malaya medical centre.
[So] Source:Cell Tissue Bank;16(4):523-30, 2015 Dec.
[Is] ISSN:1573-6814
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:The main advantage of establishing in-house bone banks is its ability to readily provide allograft bones for local surgeries. Bone procurement activities of our university bone bank during the 10 years of operation were reviewed. Socio-demographic data of donors, types of bone procured, cases of rejected bones and types of allograft bones transplanted are presented. From 179 potential donors, 73 % were accepted with 213 procured bones. Femoral head was the common bone transplanted (45 %), as it was also the most common procured (82 %). Bones were rejected mainly due to non-technical reasons (83 %) rather than positive results of microbiological (13 %) and serological (4 %) tests. Comprehensive data could not be obtained for further analysis due to difficulties in retrieving information. Therefore, quality assurance system was improved to establish more systematic documentations, as the basis of good banking practice with process control hence allowing traceability.
[Mh] Termos MeSH primário: Centros Médicos Acadêmicos/estatística & dados numéricos
Aloenxertos/estatística & dados numéricos
Bancos de Ossos/estatística & dados numéricos
Transplante Ósseo/estatística & dados numéricos
Seleção do Doador/estatística & dados numéricos
Doadores de Tecidos/estatística & dados numéricos
[Mh] Termos MeSH secundário: Adulto
Distribuição por Idade
Idoso
Idoso de 80 Anos ou mais
Feminino
Seres Humanos
Malásia/epidemiologia
Masculino
Meia-Idade
Distribuição por Sexo
Fatores Socioeconômicos
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1609
[Cu] Atualização por classe:151126
[Lr] Data última revisão:
151126
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150207
[St] Status:MEDLINE
[do] DOI:10.1007/s10561-015-9499-4



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