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[PMID]:29441974
[Au] Autor:Gudienè V
[Ti] Título:The medical treatment of Maria, Dowager Empress of the Russian Empire: an analysis of her prescription book from 1807 and 1808.
[So] Source:Pharmazie;71(11):670-679, 2016 Nov 02.
[Is] ISSN:0031-7144
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:This study analyzes the medicines that were used to treat the Dowager Russian Empress Maria, widow of Tsar Paul I, and describes the doctors who cared for her health in 1807 and 1808. The source for this research was the imperial court pharmacy prescription book 1807-1811. Hypotheses about the diseases and medical problems of the Empress and how treatment for her differed according to circumstances, particularly after the loss of her granddaughter Princess Elizabeth, have been made based on the prescriptions recorded in the book. The content of the prescriptions suggests that the Empress suffered from gastrointestinal tract disorders, skin and eye diseases, neuralgic pains and insomnia. Foreign physicians educated in European universities worked at the imperial court and implemented European medical traditions. They took high positions in the administration and the medical education system, and gradually spread their experience and modern knowledge to Tsarist Russian society.
[Mh] Termos MeSH primário: Prescrições de Medicamentos/história
Tratamento Farmacológico/história
[Mh] Termos MeSH secundário: Livros
Quimioterapia Combinada
História do Século XIX
Farmácias
Médicos
Federação Russa
[Pt] Tipo de publicação:HISTORICAL ARTICLE; JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180215
[St] Status:MEDLINE
[do] DOI:10.1691/ph.2016.6067


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[PMID]:28460016
[Au] Autor:Kathirvel S; Tripathy JP; Tun ZM; Patro BK; Singh T; Bhalla A; Devnani M; Wilkinson E
[Ad] Endereço:Department of Community Medicine, School of Public Health, Post Graduate Institute of Medical Education & Research, Chandigarh, India.
[Ti] Título:Physicians' compliance with the National Drug Policy on Malaria in a tertiary teaching hospital, India, from 2010 to 2015: a mixed method study.
[So] Source:Trans R Soc Trop Med Hyg;111(2):62-70, 2017 02 01.
[Is] ISSN:1878-3503
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Background: National drug policies are formulated to encourage rational use of drugs and to reduce drug resistance. This study assessed physicians' compliance with the National Drug Policy on Malaria at a tertiary care hospital in north India. Methods: This mixed method study extracted data from adult malaria inpatient records of the hospital from 2010-2015, and assessed drug supply at pharmacies. Physicians' practices and perspectives were explored by in-depth interviews. Compliance was assessed by severity, type of species and pregnancy status. Thematic analysis was done for the qualitative data. Results: A total of 247 case files were reviewed. Vivax malaria (41.0%) was more common than falciparum malaria (37.2%). The majority (90.8%) of cases were severe malaria. Overall compliance for use of schizonticidal drug was 73.0% in severe malaria and was only 9.5% in uncomplicated malaria. Compliance for use of gametocidal drug (primaquine) was 15.3%. Schizonticidal drugs were available in all pharmacies except the public one. Primaquine was available in only one. The main themes emerging in the thematic network analysis were physicians' misconceptions, physician-related factors, and hospital-related and drug access factors. Conclusions: The degree of compliance for severe malaria treatment was reasonably good but low for radical cure. Raising knowledge and awareness among health care providers, by using written treatment protocols and continuing medical education would improve compliance.
[Mh] Termos MeSH primário: Antimaláricos/uso terapêutico
Fidelidade a Diretrizes/estatística & dados numéricos
Malária/tratamento farmacológico
[Mh] Termos MeSH secundário: Adulto
Antimaláricos/provisão & distribuição
Atitude do Pessoal de Saúde
Feminino
Hospitais de Ensino/estatística & dados numéricos
Seres Humanos
Índia
Masculino
Meia-Idade
Farmácias/estatística & dados numéricos
Padrões de Prática Médica
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Antimalarials)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170502
[St] Status:MEDLINE
[do] DOI:10.1093/trstmh/trx020


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[PMID]:29234797
[Au] Autor:Gomez AM
[Ad] Endereço:Sexual Health and Reproductive Equity Program, School of Social Welfare, University of California, Berkeley.
[Ti] Título:Availability of Pharmacist-Prescribed Contraception in California, 2017.
[So] Source:JAMA;318(22):2253-2254, 2017 Dec 12.
[Is] ISSN:1538-3598
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Anticoncepcionais Femininos
Prescrições de Medicamentos/estatística & dados numéricos
Farmácias/estatística & dados numéricos
[Mh] Termos MeSH secundário: California
Seres Humanos
Farmacêuticos
Honorários por Prescrição de Medicamentos/estatística & dados numéricos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Contraceptive Agents, Female)
[Em] Mês de entrada:1712
[Cu] Atualização por classe:180228
[Lr] Data última revisão:
180228
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171214
[St] Status:MEDLINE
[do] DOI:10.1001/jama.2017.15674


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[PMID]:29351313
[Au] Autor:Rocca CH; Puri M; Shrestha P; Blum M; Maharjan D; Grossman D; Regmi K; Darney PD; Harper CC
[Ad] Endereço:Bixby Center for Global Reproductive Health, Department of Obstetrics, Gynecology and Reproductive Sciences, School of Medicine, University of California San Francisco, San Francisco, CA, United States of America.
[Ti] Título:Effectiveness and safety of early medication abortion provided in pharmacies by auxiliary nurse-midwives: A non-inferiority study in Nepal.
[So] Source:PLoS One;13(1):e0191174, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Expanding access to medication abortion through pharmacies is a promising avenue to reach women with safe and convenient care, yet no pharmacy provision interventions have been evaluated. This observational non-inferiority study investigated the effectiveness and safety of mifepristone-misoprostol medication abortion provided at pharmacies, compared to government-certified public health facilities, by trained auxiliary nurse-midwives in Nepal. METHODS: Auxiliary nurse-midwives were trained to provide medication abortion through twelve pharmacies and public facilities as part of a demonstration project in two districts. Eligible women were ≤63 days pregnant, aged 16-45, and had no medical contraindications. Between 2014-2015, participants (n = 605) obtained 200 mg mifepristone orally and 800 µg misoprostol sublingually or intravaginally 24 hours later, and followed-up 14-21 days later. The primary outcome was complete abortion without manual vacuum aspiration; the secondary outcome was complication requiring treatment. We assessed risk differences by facility type with multivariable logistic mixed-effects regression. RESULTS: Over 99% of enrolled women completed follow-up (n = 600). Complete abortions occurred in 588 (98·0%) cases, with ten incomplete abortions and two continuing pregnancies. 293/297 (98·7%) pharmacy participants and 295/303 (97·4%) public facility participants had complete abortions, with an adjusted risk difference falling within the pre-specified 5 percentage-point non-inferiority margin (1·5% [-0·8%, 3·8%]). No serious adverse events occurred. Five (1.7%) pharmacy and two (0.7%) public facility participants experienced a complication warranting treatment (aRD, 0.8% [-1.0%-2.7%]). CONCLUSIONS: Early mifepristone-misoprostol abortion was as effective and safe when provided by trained auxiliary nurse-midwives at pharmacies as at government-certified health facilities. Findings support policy expanding provision through registered pharmacies by trained auxiliary nurse-midwives to improve access to safe care.
[Mh] Termos MeSH primário: Aborto Induzido/enfermagem
Enfermeiras Obstétricas
[Mh] Termos MeSH secundário: Abortivos não Esteroides/administração & dosagem
Abortivos Esteroides/administração & dosagem
Aborto Induzido/educação
Aborto Induzido/métodos
Adolescente
Adulto
Feminino
Acesso aos Serviços de Saúde
Seres Humanos
Mifepristona/administração & dosagem
Misoprostol/administração & dosagem
Nepal
Enfermeiras Obstétricas/educação
Farmácias
Gravidez
Enfermagem em Saúde Pública/educação
Segurança
Resultado do Tratamento
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; OBSERVATIONAL STUDY; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Abortifacient Agents, Nonsteroidal); 0 (Abortifacient Agents, Steroidal); 0E43V0BB57 (Misoprostol); 320T6RNW1F (Mifepristone)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180221
[Lr] Data última revisão:
180221
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180120
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0191174


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[PMID]:29443670
[Au] Autor:Dafny LS
[Ad] Endereço:From the Department of General Management, Harvard Business School, Boston, and the Kennedy School of Government, Harvard University, and the National Bureau of Economic Research, Cambridge - all in Massachusetts.
[Ti] Título:Does CVS-Aetna Spell the End of Business as Usual?
[So] Source:N Engl J Med;378(7):593-595, 2018 Feb 15.
[Is] ISSN:1533-4406
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Competição Econômica
Seguradoras
Seguro Saúde/organização & administração
Farmácias/organização & administração
[Mh] Termos MeSH secundário: Instituições de Assistência Ambulatorial/organização & administração
Redução de Custos
Assistência à Saúde/economia
Assistência à Saúde/organização & administração
Instituições Associadas de Saúde
Seguro Saúde/economia
Farmácias/economia
Estados Unidos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180220
[Lr] Data última revisão:
180220
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180215
[St] Status:MEDLINE
[do] DOI:10.1056/NEJMp1717137


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[PMID]:29220334
[Au] Autor:Ferreira AO; Brandão MAF; Raposo FJ; Polonini HC; Raposo NRB
[Ad] Endereço:BF-Fox Technologies, Matias Barbosa, MG, Brazil. bffoxtec@gmail.com.
[Ti] Título:Orodispersible Films for Compounding Pharmacies.
[So] Source:Int J Pharm Compd;21(6):454-461, 2017 Nov-Dec.
[Is] ISSN:1092-4221
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Orodispersible film can be defined as a solid pharmaceutical form intended for the delivery and rapid local or systemic release of active ingredients, consisting of a water-soluble polymer film that hydrates rapidly, adhering and dissolving immediately when placed on the tongue or in the oral cavity (oral, palatal, gingival, lingual, or sublingual), without the need for water administration or mastication. Due to its outstanding importance in cases of emergency, practicality of use by patients in transit, and high adherence, orodispersible film has evolved in popularity and success among consumers. It is a promising dosage form for compounding pharmacies, as simpler technologies are being developed to make the compound process easier and faster for the pharmacist. This article aims to explore some of the basics on orodispersible film and the main possible preparations to be developed in compounding pharmacies worldwide.
[Mh] Termos MeSH primário: Sistemas de Liberação de Medicamentos
Polímeros/química
[Mh] Termos MeSH secundário: Administração Oral
Química Farmacêutica
Formas de Dosagem
Composição de Medicamentos
Farmácias
Solubilidade
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Dosage Forms); 0 (Polymers)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180220
[Lr] Data última revisão:
180220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171209
[St] Status:MEDLINE


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[PMID]:29361658
[Au] Autor:Steiner DJ; Thomson Reuters Accelus.
[Ti] Título:Pharmaceuticals and Medical Devices: Medicare Part D.
[So] Source:Issue Brief Health Policy Track Serv;2017:1-32, 2017 Dec 26.
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Medicare Part D/organização & administração
Medicare/organização & administração
[Mh] Termos MeSH secundário: Analgésicos Opioides
Criança
Serviços de Saúde da Criança
Custos de Medicamentos
Farmacoeconomia
Honorários e Preços
Acesso aos Serviços de Saúde
Seres Humanos
Reembolso de Seguro de Saúde
Medicaid
Medicare/legislação & jurisprudência
Medicare Part C
Medicare Part D/legislação & jurisprudência
Transtornos Relacionados ao Uso de Opioides
Patient Protection and Affordable Care Act
Farmácias/economia
Previdência Social
Governo Estadual
Estados Unidos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Analgesics, Opioid)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180219
[Lr] Data última revisão:
180219
[Sb] Subgrupo de revista:T
[Da] Data de entrada para processamento:180124
[St] Status:MEDLINE


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[PMID]:29361657
[Au] Autor:Steiner DJ; Thomson Reuters Accelus.
[Ti] Título:Pharmaceuticals and Medical Devices: Cost Savings.
[So] Source:Issue Brief Health Policy Track Serv;2017:1-31, 2017 Dec 26.
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Custos de Medicamentos
Indústria Farmacêutica/economia
Farmacoeconomia/organização & administração
Medicamentos sob Prescrição/economia
[Mh] Termos MeSH secundário: Canadá
Comércio/economia
Redução de Custos
Dedutíveis e Cosseguros
Revelação
Aprovação de Drogas
Custos de Medicamentos/legislação & jurisprudência
Medicamentos Genéricos/economia
Competição Econômica
Farmacoeconomia/legislação & jurisprudência
Epinefrina/economia
Seres Humanos
Adesão à Medicação
Conduta do Tratamento Medicamentoso/economia
Medicamentos sem Prescrição/economia
Farmácias/economia
Equivalência Terapêutica
Estados Unidos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Drugs, Generic); 0 (Nonprescription Drugs); 0 (Prescription Drugs); YKH834O4BH (Epinephrine)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180219
[Lr] Data última revisão:
180219
[Sb] Subgrupo de revista:T
[Da] Data de entrada para processamento:180124
[St] Status:MEDLINE


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[PMID]:29176836
[Au] Autor:Belachew SA; Tilahun F; Ketsela T; Achaw Ayele A; Kassie Netere A; Getnet Mersha A; Befekadu Abebe T; Melaku Gebresillassie B; Getachew Tegegn H; Asfaw Erku D
[Ad] Endereço:Department of Clinical Pharmacy, School of Pharmacy, University of Gondar Chechela Street, Lideta Sub city Kebele, Gondar, Ethiopia.
[Ti] Título:Competence in metered dose inhaler technique among community pharmacy professionals in Gondar town, Northwest Ethiopia: Knowledge and skill gap analysis.
[So] Source:PLoS One;12(11):e0188360, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: When compared to systemic administration, if used correctly inhalers deliver a smaller enough percent of the drug right to the site of action in the lungs, with a faster onset of effect and with reduced systemic availability that minimizes adverse effects. However, the health professionals' and patients' use of metered dose inhaler is poor. OBJECTIVE: This study was aimed to explore community pharmacy professionals' (pharmacists' and druggists') competency on metered dose inhaler (MDI) technique. METHOD: A cross sectional study was employed on pharmacy professionals working in community drug retail outlets in Gondar town, northwest Ethiopia from March to May 2017. Evaluation tool was originally taken and adapted from the National Asthma Education and Prevention Programmes of America (NAEPP) step criteria for the demonstration of a metered dose inhaler to score the knowledge/proficiency of using the inhaler. RESULT: Among 70 community pharmacy professionals approached, 62 (32 pharmacists and 30 druggists/Pharmacy technicians) completed the survey with a response rate of 85.6%. Only three (4.8%) respondents were competent by demonstrating the vital steps correctly. Overall, only 13 participants got score seven or above, but most of them had missed the essential steps which included steps 1, 2, 5, 6, 7 or 8. There was a significant difference (P = 0.015) in competency of demonstrating adequate inhalational technique among respondents who took training on basic inhalational techniques and who did not. CONCLUSION: This study shown that, community pharmacy professionals' competency of MDI technique was very poor. So as to better incorporate community pharmacies into future asthma illness management and optimize the contribution of pharmacists, interventions would emphasis to improve the total competence of community pharmacy professionals through establishing and providing regular educational programs.
[Mh] Termos MeSH primário: Conhecimento
Inaladores Dosimetrados
Farmácias
Farmacêuticos
Competência Profissional
Distribuição Espacial da População
[Mh] Termos MeSH secundário: Administração por Inalação
Adulto
Demografia
Etiópia
Feminino
Seres Humanos
Masculino
Meia-Idade
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171219
[Lr] Data última revisão:
171219
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171128
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0188360


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[PMID]:28448327
[Au] Autor:Nguyen VH
[Ad] Endereço:Public Health Program, Department of Health Sciences, School of Health Professions, University of Missouri, Columbia, Missouri, USA.
[Ti] Título:Community osteoporosis screening services for the prevention of osteoporotic fractures in population health: a literature review.
[So] Source:Int J Evid Based Healthc;15(2):43-52, 2017 Jun.
[Is] ISSN:1744-1609
[Cp] País de publicação:Australia
[La] Idioma:eng
[Ab] Resumo:AIM: To determine the implications of the reviewed literature in population health improvement. METHOD: A review of the literature was conducted with the search of four databases: PubMed, PsycINFO, ERIC, and Google Scholar. Search terms entered into these databases were 'osteoporosis community'. After a thorough review of all search results, 11 studies were found to be community osteoporosis screening services, and descriptions of each study's participants and location, details and descriptions of each study's community osteoporosis screening service, and effectiveness on outcome measure(s) for each study's objective were reviewed and examined to determine their implications on population health. RESULTS: Nine of the 11 studies on community osteoporosis screening services were conducted at community pharmacy settings, and all studies included participants that were all or mostly older women, with only three studies that included men as participants. In addition to osteoporosis screening, all studies included osteoporosis education and/or counseling with the exception of one study. Various outcome measures were assessed in these studies, and with the exception of osteoporosis treatment adherence, weight-bearing exercise and osteoporosis-specified quality of life, community osteoporosis screening services showed positive outcomes in increasing osteoporosis awareness, osteoporosis knowledge, osteoporosis risk identification, calcium intake, service satisfaction, primary care physician perspective, and financial sustainability. In particular, community osteoporosis screening services are helpful in identifying those with osteoporosis or are at moderate risk to high risk, and they are effective in increasing outcomes that help prevent osteoporotic fractures, such as osteoporosis medication prescription and calcium intake. Furthermore, participants feel satisfied in partaking in community osteoporosis screening services, primary care physicians do believe that they are useful, and they are financially stable as they earn profit net gains. CONCLUSION: Community osteoporosis screening services provide a cost-effective approach towards preventing osteoporotic fractures for population health, particularly in identifying osteoporosis or high risk of the disease in populations. This review determined preventive measures for osteoporotic fractures, such as increased calcium intake and osteoporosis medication prescriptions, resulting in decreased osteoporotic fractures and increased population health improvement.
[Mh] Termos MeSH primário: Programas de Rastreamento/organização & administração
Fraturas por Osteoporose/prevenção & controle
Saúde da População
[Mh] Termos MeSH secundário: Idoso
Cálcio/administração & dosagem
Feminino
Conhecimentos, Atitudes e Prática em Saúde
Seres Humanos
Masculino
Osteoporose/tratamento farmacológico
Farmácias
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
SY7Q814VUP (Calcium)
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171215
[Lr] Data última revisão:
171215
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170428
[St] Status:MEDLINE
[do] DOI:10.1097/XEB.0000000000000104



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