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Referências encontradas : 4100 [refinar]
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[PMID]:28450400
[Au] Autor:Weber EJ; Hirst E; Marsh M
[Ad] Endereço:Department of Emergency Medicine, University of California, San Francisco, CA 94143, US.
[Ti] Título:The patient's dilemma: attending the emergency department with a minor illness.
[So] Source:BMJ;357:j1941, 2017 04 27.
[Is] ISSN:1756-1833
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Tomada de Decisões/fisiologia
Serviço Hospitalar de Emergência/utilização
[Mh] Termos MeSH secundário: Erros de Diagnóstico
Mau Uso de Serviços de Saúde/estatística & dados numéricos
Seres Humanos
[Pt] Tipo de publicação:EDITORIAL
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171128
[Lr] Data última revisão:
171128
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170429
[St] Status:MEDLINE
[do] DOI:10.1136/bmj.j1941


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[PMID]:28802187
[Au] Autor:Lievens Y; De Schutter H; Stellamans K; Rosskamp M; Van Eycken L; Belgian College for Physicians in Radiation Oncology
[Ad] Endereço:Radiation Oncology Department, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium. Electronic address: yolande.lievens@uzgent.be.
[Ti] Título:Radiotherapy access in Belgium: How far are we from evidence-based utilisation?
[So] Source:Eur J Cancer;84:102-113, 2017 Oct.
[Is] ISSN:1879-0852
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: Underutilisation of radiotherapy has been observed worldwide. To evaluate the current situation in Belgium, optimal utilisation proportions (OUPs) adopted from the European SocieTy for Radiotherapy and Oncology - Health Economics in Radiation Oncology (ESTRO-HERO) project were compared to actual utilisation proportions (AUPs) and with radiotherapy advised during the multidisciplinary cancer team (MDT) meetings. In addition, the impact of independent variables was analysed. MATERIALS AND METHODS: AUPs and advised radiotherapy were calculated overall and by cancer type for 110,810 unique cancer diagnoses in 2009-2010. Radiotherapy utilisation was derived from reimbursement data and distinguished between palliative and curative intent external beam radiotherapy (EBRT) and/or brachytherapy (BT). Sensitivity analyses regarding the influence of the follow-up period, the survival length and patient's age were performed. Advised radiotherapy was calculated based on broad treatment categories as reported at MDT meetings. RESULTS: The overall AUP of 37% (39% including BT) was lower than the OUP of 53%, but in line with advised radiotherapy (35%). Large variations by tumour type were observed: in some tumours (e.g. lung and prostate cancer) AUP was considerably lower than OUP, whereas in others there was reasonable concordance (e.g. breast and rectal cancer). Overall, 84% of treatments started within 9 months following diagnosis. Survival time influenced AUP in a cancer type-dependent way. Elderly patients received less radiotherapy. CONCLUSION: Although the actually delivered radiotherapy in Belgium aligns well to MDT advices, it is lower than the evidence-based optimum. Further analysis of potential barriers is needed for radiotherapy forecasting and planning, and in order to promote adequate access to radiotherapy.
[Mh] Termos MeSH primário: Braquiterapia/tendências
Medicina Baseada em Evidências/tendências
Acesso aos Serviços de Saúde/tendências
Mau Uso de Serviços de Saúde/tendências
Neoplasias/radioterapia
Padrões de Prática Médica/tendências
Avaliação de Processos (Cuidados de Saúde)/tendências
[Mh] Termos MeSH secundário: Demandas Administrativas em Assistência à Saúde
Fatores Etários
Idoso
Idoso de 80 Anos ou mais
Bélgica
Braquiterapia/economia
Braquiterapia/utilização
Tomada de Decisão Clínica
Bases de Dados Factuais
Medicina Baseada em Evidências/economia
Feminino
Fidelidade a Diretrizes/tendências
Custos de Cuidados de Saúde/tendências
Acesso aos Serviços de Saúde/economia
Mau Uso de Serviços de Saúde/economia
Seres Humanos
Reembolso de Seguro de Saúde/tendências
Masculino
Meia-Idade
Neoplasias/economia
Neoplasias/mortalidade
Neoplasias/patologia
Cuidados Paliativos/tendências
Equipe de Assistência ao Paciente/tendências
Seleção de Pacientes
Guias de Prática Clínica como Assunto
Padrões de Prática Médica/economia
Avaliação de Processos (Cuidados de Saúde)/economia
Análise de Sobrevida
Fatores de Tempo
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171010
[Lr] Data última revisão:
171010
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170813
[St] Status:MEDLINE


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[PMID]:28797032
[Au] Autor:Okonji DO; Sinha R; Phillips I; Fatz D; Ring A
[Ad] Endereço:Breast Unit, Royal Marsden Hospital NHS Foundation Trust, Sutton SM2 5PT, UK.
[Ti] Título:Comprehensive geriatric assessment in 326 older women with early breast cancer.
[So] Source:Br J Cancer;117(7):925-931, 2017 Sep 26.
[Is] ISSN:1532-1827
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: One-third of new early breast cancer diagnoses occur in women over 70 years old. However, older women are less likely to receive radical curative treatments. This study prospectively evaluated a cohort of older women using a Comprehensive Geriatric Assessment (CGA) to determine whether fitness explained the apparent under-treatment in this patient group. METHODS: In this multi-centre prospective study, patients aged ⩾70 years with Stages I-III breast cancer underwent a pretreatment baseline CGA consisting of eight assessment tools. Patients were defined as 'fit' if they had normal score in seven out of eight of the assessment tools. 'High risk' patients were defined as those with grade 3, ER negative, HER2 positive, or node positive breast cancer. RESULTS: Data on 326 patients were available for full analysis. The median age was 77 years. In all, 182 (56%) of the total population were defined as high risk, with 49%, 61% and 53% of those in the 70-74, 75-84 and ⩾85 years age groups respectively having high risk tumours. A total of 301 patients had sufficient CGA records of whom 131 (44%) were reported as fit, with 34%, 54% and 12% of them in the 70-74, 75-84 and ⩾85 years age groups respectively. More fit than unfit patients underwent primary breast surgery (100% vs 91%, P=0.0002), axillary surgery (92% vs 84%, P=0.0340), and adjuvant chemotherapy for high-risk disease (51% vs 20%, P=0.0001). Rates of adjuvant radiotherapy after wide local excision were not significantly different (88% vs 90% respectively, P=0.8195). CONCLUSIONS: In this study, all women ⩾70 years deemed fit by CGA underwent primary surgery. Nearly 50% of fit women with high-risk disease did not receive adjuvant chemotherapy suggesting under treatment in this group.
[Mh] Termos MeSH primário: Neoplasias da Mama/terapia
Quimioterapia Adjuvante/utilização
Avaliação Geriátrica
Mastectomia/utilização
Radioterapia Adjuvante/utilização
[Mh] Termos MeSH secundário: Idoso
Idoso de 80 Anos ou mais
Antineoplásicos/uso terapêutico
Neoplasias da Mama/química
Neoplasias da Mama/patologia
Feminino
Mau Uso de Serviços de Saúde
Seres Humanos
Metástase Linfática
Estudos Prospectivos
Receptor ErbB-2/análise
Receptores Estrogênicos/análise
Medição de Risco
[Pt] Tipo de publicação:JOURNAL ARTICLE; MULTICENTER STUDY
[Nm] Nome de substância:
0 (Antineoplastic Agents); 0 (Receptors, Estrogen); EC 2.7.10.1 (ERBB2 protein, human); EC 2.7.10.1 (Receptor, ErbB-2)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171005
[Lr] Data última revisão:
171005
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170811
[St] Status:MEDLINE
[do] DOI:10.1038/bjc.2017.257


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[PMID]:28666541
[Au] Autor:Eggemann H; Ignatov T; Burger E; Costa SD; Ignatov A
[Ad] Endereço:Department of Obstetrics and Gynecology, Otto-von-Guericke University, Magdeburg, Germany.
[Ti] Título:Management of elderly women with endometrial cancer.
[So] Source:Gynecol Oncol;146(3):519-524, 2017 Sep.
[Is] ISSN:1095-6859
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Elderly women with endometrial cancer receive less therapy in comparison with their younger counterparts. The exact reason(s) for this treatment strategy remains unclear. PATIENTS AND METHODS: We performed a multicenter, retrospective registry-based study of 1550 patients with endometrial cancer. The outcome measure was the reason for not performing the indicated treatment. RESULTS: Median follow-up was 76.8months. A total of 1550 women were eligible for analysis: 353 (22.7%) were younger than 60years, 521 (33.6%) 61-70years, 515 (33.2%) 71-80years, and 161 (10.4%) were aged 81years old and older. Elderly women were more likely to have non-endometrioid, undifferentiated endometrial cancer at an advanced stage. Patients younger than 60years were more likely to receive lymphadenectomy, brachytherapy, external-beam radiotherapy (EBRT) and systemic therapy compared with the group of patients aged older than 70years. We investigated the reason why elderly women were undertreated. The rate of indicated therapies that were not recommended by the physicians proportionally increased with an increase in patient age. Interestingly, the rate of contraindications because of performance status and/or medical disease also increased proportionally with increasing patient age. Notably, in the groups of patients older than 70years, patient refusal was a very uncommon reason for failure to perform the indicated therapy. CONCLUSIONS: Elderly women with EC are more likely undertreated because the therapy was not recommended by the physicians based on performance status and medical diseases rather than patient refusal.
[Mh] Termos MeSH primário: Neoplasias do Endométrio/terapia
Nível de Saúde
Excisão de Linfonodo
Padrões de Prática Médica
[Mh] Termos MeSH secundário: Fatores Etários
Idoso
Idoso de 80 Anos ou mais
Antineoplásicos
Braquiterapia
Comorbidade
Contraindicações
Neoplasias do Endométrio/patologia
Feminino
Mau Uso de Serviços de Saúde
Seres Humanos
Meia-Idade
Sistema de Registros
Estudos Retrospectivos
Recusa do Paciente ao Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE; MULTICENTER STUDY
[Nm] Nome de substância:
0 (Antineoplastic Agents)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170702
[St] Status:MEDLINE


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[PMID]:28542699
[Au] Autor:Rockwell KL
[Ad] Endereço:Honigman Miller Schwartz & Cohn LLP, Bloomfield Hills, Michigan.
[Ti] Título:Direct-to-Consumer Medical Testing in the Era of Value-Based Care.
[So] Source:JAMA;317(24):2485-2486, 2017 Jun 27.
[Is] ISSN:1538-3598
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Triagem e Testes Direto ao Consumidor
Mau Uso de Serviços de Saúde/prevenção & controle
Procedimentos Desnecessários
[Mh] Termos MeSH secundário: Controle de Custos
Assistência à Saúde/economia
Assistência à Saúde/normas
Triagem e Testes Direto ao Consumidor/economia
Triagem e Testes Direto ao Consumidor/legislação & jurisprudência
Triagem e Testes Direto ao Consumidor/tendências
Testes Genéticos
Custos de Cuidados de Saúde
Mau Uso de Serviços de Saúde/economia
Mau Uso de Serviços de Saúde/tendências
Seres Humanos
Qualidade da Assistência à Saúde/economia
Qualidade da Assistência à Saúde/normas
Governo Estadual
Estados Unidos
United States Federal Trade Commission
United States Food and Drug Administration
Procedimentos Desnecessários/economia
Procedimentos Desnecessários/tendências
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1707
[Cu] Atualização por classe:171026
[Lr] Data última revisão:
171026
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170526
[St] Status:MEDLINE
[do] DOI:10.1001/jama.2017.5929


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[PMID]:28537118
[Au] Autor:Muheim L
[Ad] Endereço:1 Institut für Hausarztmedizin, Horten-Zentrum für praxisorientierte Forschung und Wissenstransfer, Universitätsspital Zürich.
[Ti] Título:Kontinuität in der Grundversorgung scheint Anzahl an Hospitalisationen zu reduzieren..
[So] Source:Praxis (Bern 1994);106(11):599-600, 2017.
[Is] ISSN:1661-8157
[Cp] País de publicação:Switzerland
[La] Idioma:ger
[Mh] Termos MeSH primário: Continuidade da Assistência ao Paciente
Acesso aos Serviços de Saúde
Mau Uso de Serviços de Saúde/prevenção & controle
Hospitalização/estatística & dados numéricos
Atenção Primária à Saúde
[Mh] Termos MeSH secundário: Idoso
Idoso de 80 Anos ou mais
Feminino
Seres Humanos
Masculino
Meia-Idade
Estudos Retrospectivos
Suíça
[Pt] Tipo de publicação:JOURNAL ARTICLE; OBSERVATIONAL STUDY
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170525
[St] Status:MEDLINE
[do] DOI:10.1024/1661-8157/a002685


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[PMID]:28498197
[Au] Autor:Baxi SS; Kale M; Keyhani S; Roman BR; Yang A; Derosa AP; Korenstein D
[Ad] Endereço:*Department of Medicine, Head and Neck Oncology Service, Memorial Sloan Kettering Cancer Center †Department of Medicine, Mount Sinai Hospital, New York, NY ‡Department of Medicine, University of California San Francisco, San Francisco, CA §Department of Surgery ∥Center for Health Policy and Outcomes ¶Medical Library, Memorial Sloan Kettering Cancer Center, New York, NY.
[Ti] Título:Overuse of Health Care Services in the Management of Cancer: A Systematic Review.
[So] Source:Med Care;55(7):723-733, 2017 Jul.
[Is] ISSN:1537-1948
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Overuse, the provision of health services for which harms outweigh the benefits, results in suboptimal patient care and may contribute to the rising costs of cancer care. We performed a systematic review of the evidence on overuse in oncology. METHODS: We searched Medline, EMBASE, the Cochrane Library, Web of Science, SCOPUS databases, and 2 grey literature sources, for articles published between December 1, 2011 and March 10, 2017. We included publications from December 2011 to evaluate the literature since the inception of the ABIM Foundation's Choosing Wisely initiative in 2012. We included original research articles quantifying overuse of any medical service in patients with a cancer diagnosis when utilizing an acceptable standard to define care appropriateness, excluding studies of cancer screening. One of 4 investigator reviewed titles and abstracts and 2 of 4 reviewed each full-text article and extracted data. Methodology used PRISMA guidelines. RESULTS: We identified 59 articles measuring overuse of 154 services related to imaging, procedures, and therapeutics in cancer management. The majority of studies addressed adult or geriatric patients (98%) and focused on US populations (76%); the most studied services were diagnostic imaging in low-risk prostate and breast cancer. Few studies evaluated active cancer therapeutics or interventions aimed at reducing overuse. Rates of overuse varied widely among services and among studies of the same service. CONCLUSIONS: Despite recent attention to overuse in cancer, evidence identifying areas of overuse remains limited. Broader investigation, including assessment of active cancer treatment, is critical for identifying improvement targets to optimize value in cancer care.
[Mh] Termos MeSH primário: Mau Uso de Serviços de Saúde
Neoplasias
[Mh] Termos MeSH secundário: Pesquisa sobre Serviços de Saúde
Seres Humanos
Qualidade da Assistência à Saúde
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170728
[Lr] Data última revisão:
170728
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170513
[St] Status:MEDLINE
[do] DOI:10.1097/MLR.0000000000000734


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[PMID]:28418455
[Au] Autor:Smits M; Rutten M; Keizer E; Wensing M; Westert G; Giesen P
[Ad] Endereço:From Radboud University Medical Center, Radboud Institute for Health Sciences, Scientific Center for Quality of Healthcare (IQ Healthcare), Nijmegen, the Netherlands.
[Ti] Título:The Development and Performance of After-Hours Primary Care in the Netherlands: A Narrative Review.
[So] Source:Ann Intern Med;166(10):737-742, 2017 May 16.
[Is] ISSN:1539-3704
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:In many Western countries, hospital emergency departments are overcrowded, leading to the desire to strengthen primary care, particularly after hours. To achieve this goal, an increasing number of Western nations are reorganizing their after-hours primary care systems into large-scale primary care physician (PCP) cooperatives. This article provides an overview of the organization, performance, and development of PCP cooperatives in the Netherlands. The Dutch after-hours primary care system might offer opportunities for other countries facing problems with after-hours care and inappropriate emergency department visits. During the past several years, the number of contacts with Dutch PCP cooperatives has increased to 245 contacts per 1000 citizens per year. Many contacts (45%) are nonurgent, and about half occur as part of a series of primary care contacts. Low accessibility and availability of daytime primary care are related to greater use of after-hours primary care. To prevent unnecessary attendance at the cooperatives, physicians advocate copayment, a stricter triage system, and a larger role for telephone doctors. More than half of the PCP cooperatives in the Netherlands have integrated with hospital emergency departments, forming "emergency care access points." This collaboration has decreased emergency department use by 13% to 22%, and treatment of self-referrals by PCP cooperatives in emergency care access points is safe and cost-effective. Direct access to diagnostic facilities may optimize efficiency even more. Other recent developments include access to electronic health records of daytime primary care practices, task substitution from physicians to nurses, and the launch of a 2-year training program for PCPs to become experts in emergency care.
[Mh] Termos MeSH primário: Plantão Médico/organização & administração
Serviço Hospitalar de Emergência/organização & administração
Atenção Primária à Saúde/organização & administração
[Mh] Termos MeSH secundário: Registros Eletrônicos de Saúde
Serviço Hospitalar de Emergência/utilização
Fidelidade a Diretrizes
Mau Uso de Serviços de Saúde/prevenção & controle
Seres Humanos
Países Baixos
Segurança do Paciente
Guias de Prática Clínica como Assunto
Telefone
Triagem/métodos
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170531
[Lr] Data última revisão:
170531
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170419
[St] Status:MEDLINE
[do] DOI:10.7326/M16-2776


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[PMID]:28350733
[Au] Autor:Thompson KM; Tozier WL
[Ad] Endereço:At the time this article was written, Katherine M. Thompson was a student in the University of Washington's MEDEX program in Seattle, Wash. She is now an employee of Valley Emergency Physicians and practices in the ED at California Hospital Medical Center in Los Angeles, Calif. William L. Tozier is a faculty advisor for the University of Washington's MEDEX program. The authors have disclosed no potential conflicts of interest, financial or otherwise.
[Ti] Título:Using PAs in prehospital environments to reduce ED and EMS overuse.
[So] Source:JAAPA;30(4):49-52, 2017 Apr.
[Is] ISSN:1547-1896
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Emergency medical services (EMS) and EDs in large cities are burdened with a significant number of patients with chronic disease who have limited options for receiving proper care. Despite their relatively small numbers, these "superusers" can have a significant effect on EMS, particularly in large cities. Additionally, EDs are not designed to provide chronic and continuous healthcare. This article describes how several organizations use physician assistants to manage these patients.
[Mh] Termos MeSH primário: Medicina de Emergência/organização & administração
Serviço Hospitalar de Emergência/organização & administração
Mau Uso de Serviços de Saúde/prevenção & controle
Equipe de Assistência ao Paciente/organização & administração
Assistentes Médicos/estatística & dados numéricos
[Mh] Termos MeSH secundário: Doença Crônica/terapia
Seres Humanos
Qualidade da Assistência à Saúde
Estados Unidos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171004
[Lr] Data última revisão:
171004
[Sb] Subgrupo de revista:T
[Da] Data de entrada para processamento:170329
[St] Status:MEDLINE
[do] DOI:10.1097/01.JAA.0000513350.53148.25


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[PMID]:28291383
[Au] Autor:Pinheiro LC; Wheeler SB; Reeder-Hayes KE; Samuel CA; Olshan AF; Reeve BB
[Ad] Endereço:Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC.
[Ti] Título:Investigating Associations Between Health-Related Quality of Life and Endocrine Therapy Underuse in Women With Early-Stage Breast Cancer.
[So] Source:J Oncol Pract;13(5):e463-e473, 2017 May.
[Is] ISSN:1935-469X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:PURPOSE: Endocrine therapy (ET) underuse puts women at increased risk for breast cancer (BC) recurrence. Our objective was to determine if health-related quality of life (HRQOL) subgroups were associated with underuse. METHODS: Data came from the third phase of the Carolina Breast Cancer Study. We included 1,599 women with hormone receptor-positive BC age 20 to 74 years. HRQOL was measured, on average, 5 months postdiagnosis. Subgroups were derived using latent profile (LP) analysis. Underuse was defined as not initiating or adhering to ET by 36 months postdiagnosis. Multivariable logistic regression models estimated adjusted odds ratios (ORs) between HRQOL LPs and underuse. The best HRQOL LP was the reference. Chemotherapy- and race-stratified models were estimated, separately. RESULTS: Initiation analyses included 953 women who had not begun ET by their 5-month survey. Of these, 154 never initiated ET. Adherence analyses included 1,114 ET initiators, of whom 211 were nonadherent. HRQOL was not significantly associated with noninitiation, except among nonchemotherapy users, with membership in the poorest LP associated with increased odds of noninitiation (adjusted OR, 5.5; 95% CI, 1.7 to 17.4). Membership in the poorest LPs was associated with nonadherence (LP1: adjusted OR, 2.2; 95% CI, 1.2 to 4.0 and LP2: adjusted OR,1.9; 95% CI, 1.1 to 3.6). Membership in the poorest LP was associated with nonadherence among nonchemotherapy users (adjusted OR, 2.1; 95% CI, 1.2 to 5.1). CONCLUSION: Our results suggest women with poor HRQOL during active treatment may be at increased risk for ET underuse. Focusing on HRQOL, a modifiable factor, may improve targeting of future interventions early in the BC continuum to improve ET initiation and adherence and prevent BC recurrence.
[Mh] Termos MeSH primário: Neoplasias da Mama/epidemiologia
Mau Uso de Serviços de Saúde
Qualidade de Vida
[Mh] Termos MeSH secundário: Adulto
Idoso
Protocolos de Quimioterapia Combinada Antineoplásica
Neoplasias da Mama/tratamento farmacológico
Neoplasias da Mama/patologia
Terapia Combinada
Comorbidade
Feminino
Seres Humanos
Meia-Idade
Estadiamento de Neoplasias
North Carolina/epidemiologia
Razão de Chances
Fatores de Risco
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171103
[Lr] Data última revisão:
171103
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170315
[St] Status:MEDLINE
[do] DOI:10.1200/JOP.2016.018630



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