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Pesquisa : N03.219.702 [Categoria DeCS]
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[PMID]:29425246
[Au] Autor:Sicking J; Guhr T; Schäfer R
[Ad] Endereço:Fakultät für Physik, Universität Duisburg-Essen, 46057 Duisburg, Germany.
[Ti] Título:Concurrent credit portfolio losses.
[So] Source:PLoS One;13(2):e0190263, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:We consider the problem of concurrent portfolio losses in two non-overlapping credit portfolios. In order to explore the full statistical dependence structure of such portfolio losses, we estimate their empirical pairwise copulas. Instead of a Gaussian dependence, we typically find a strong asymmetry in the copulas. Concurrent large portfolio losses are much more likely than small ones. Studying the dependences of these losses as a function of portfolio size, we moreover reveal that not only large portfolios of thousands of contracts, but also medium-sized and small ones with only a few dozens of contracts exhibit notable portfolio loss correlations. Anticipated idiosyncratic effects turn out to be negligible. These are troublesome insights not only for investors in structured fixed-income products, but particularly for the stability of the financial sector. JEL codes: C32, F34, G21, G32, H81.
[Mh] Termos MeSH primário: Investimentos em Saúde/economia
[Mh] Termos MeSH secundário: Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180309
[Lr] Data última revisão:
180309
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180210
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0190263


  2 / 7694 MEDLINE  
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[PMID]:29172678
[Au] Autor:Sharma RA; Fumi L; Audisio RA; Denys A; Wood BJ; Pignatti F
[Ad] Endereço:1 Department of Oncology, NIHR Oxford Biomedical Research Centre, University of Oxford , Oxford , UK.
[Ti] Título:Commentary: how will interventional oncology navigate the "valleys of death" for new medical devices?
[So] Source:Br J Radiol;91(1083):20170643, 2018 Feb.
[Is] ISSN:1748-880X
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Whereas clinical trials of cancer drugs have methodological standards and conventional primary endpoints, these are not necessarily applicable to the clinical development of loco-regional treatments and new medical devices. The current challenge is to generate high-level clinical evidence for loco-regional treatments to define the benefits for patients. In this article, we argue that, to generate convincing evidence of clinical efficacy and safety, the collective coherence of the entire data package is often more important than the primary endpoint of one clinical trial. We also propose that, when a comprehensive clinical data package is not feasible, limited clinical data can be supplemented with other types of evidence. Emerging life science companies often define the "valley of death" after securing initial investment to translate an early medical device concept to a development stage that is attractive to funders. Unfortunately for this industry, there is a second "valley of death" if the focus and goal is only regulatory approval, to the neglect of clinical acceptance and reimbursement. For the emerging specialism of interventional oncology, it is critical to plan a clear line of sight for each new medical device to avoid the valleys of death and to demonstrate the clinical benefit. Increased international guidance to establish realistic yet convincing standards in this area may avoid attrition of potentially beneficial devices and therapeutic procedures in the valleys of death.
[Mh] Termos MeSH primário: Equipamentos e Provisões/economia
Oncologia
Neoplasias/terapia
[Mh] Termos MeSH secundário: Ensaios Clínicos como Assunto
Aprovação de Equipamentos
Segurança de Equipamentos
Seres Humanos
Investimentos em Saúde
Segurança do Paciente
Estados Unidos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180226
[Lr] Data última revisão:
180226
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171128
[St] Status:MEDLINE
[do] DOI:10.1259/bjr.20170643


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[PMID]:29191434
[Au] Autor:Scheiring G; Stefler D; Irdam D; Fazekas M; Azarova A; Kolesnikova I; Köllo J; Popov V; Szelenyi I; Marmot M; Murphy M; McKee M; Bobak M; King L
[Ad] Endereço:Department of Sociology, University of Cambridge, Cambridge, UK. Electronic address: gs385@cam.ac.uk.
[Ti] Título:The gendered effects of foreign investment and prolonged state ownership on mortality in Hungary: an indirect demographic, retrospective cohort study.
[So] Source:Lancet Glob Health;6(1):e95-e102, 2018 Jan.
[Is] ISSN:2214-109X
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Research on the health outcomes of globalisation and economic transition has yielded conflicting results, partly due to methodological and data limitations. Specifically, the outcomes of changes in foreign investment and state ownership need to be examined using multilevel data, linking macro-effects and micro-effects. We exploited the natural experiment offered by the Hungarian economic transition by means of a multilevel study designed to address these gaps in the scientific literature. METHODS: For this indirect demographic, retrospective cohort study, we collected multilevel data related to Hungary between 1995 and 2004 from the PrivMort database and other sources at the town, company, and individual level to assess the relation between the dominant company ownership of a town and mortality. We grouped towns into three ownership categories: dominant state, domestic private, and foreign ownership. We did population surveys in these towns to collect data on vital status and other characteristics of survey respondents' relatives. We assessed the relation between dominant ownership and mortality at the individual level. We used discrete-time survival modelling, adjusting for town-level and individual-level confounders, with clustered SEs. FINDINGS: Of 83 eligible towns identified, we randomly selected 52 for inclusion in the analysis and analysed ownership data from 262 companies within these towns. Additionally, between June 16, 2014, and Dec 22, 2014, we collected data on 78 622 individuals from the 52 towns, of whom 27 694 were considered eligible. After multivariable adjustment, we found that women living in towns with prolonged state ownership had significantly lower odds of dying than women living in towns dominated by domestic private ownership (odds ratio [OR] 0·74, 95% CI 0·61-0·90) or by foreign investment (OR 0·80, 0·69-0·92). INTERPRETATION: Prolonged state ownership was associated with protection of life chances during the post-socialist transformation for women. The indirect economic benefits of foreign investment do not translate automatically into better health without appropriate industrial and social policies. FUNDING: The European Research Council.
[Mh] Termos MeSH primário: Disparidades nos Níveis de Saúde
Internacionalidade
Investimentos em Saúde
Mortalidade/tendências
Propriedade/estatística & dados numéricos
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Feminino
Seres Humanos
Hungria/epidemiologia
Masculino
Meia-Idade
Análise Multinível
Estudos Retrospectivos
Distribuição por Sexo
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180221
[Lr] Data última revisão:
180221
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171202
[St] Status:MEDLINE


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[PMID]:27771546
[Au] Autor:Yoon J; Luck J
[Ad] Endereço:Health Management and Policy Programs, College of Public Health and Human Sciences, Oregon State University, 464 Waldo Hall, Corvallis, OR 97331, USA. Electronic address: jangho.yoon@oregonstate.edu.
[Ti] Título:Intersystem return on investment in public mental health: Positive externality of public mental health expenditure for the jail system in the U.S.
[So] Source:Soc Sci Med;170:133-142, 2016 12.
[Is] ISSN:1873-5347
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:This study examines the extent to which increased public mental health expenditures lead to a reduction in jail populations and computes the associated intersystem return on investment (ROI). We analyze unique panel data on 44 U.S. states and D.C. for years 2001-2009. To isolate the intersystem spillover effect, we exploit variations across states and over time within states in per capita public mental health expenditures and average daily jail inmates. Regression models control for a comprehensive set of determinants of jail incarcerations as well as unobserved determinants specific to state and year. Findings show a positive spillover benefit of increased public mental health spending on the jail system: a 10% increase in per capita public inpatient mental health expenditure on average leads to a 1.5% reduction in jail inmates. We also find that the positive intersystem externality of increased public inpatient mental health expenditure is greater when the level of community mental health spending is lower. Similarly, the intersystem spillover effect of community mental health expenditure is larger when inpatient mental health spending is lower. We compute that overall an extra dollar in public inpatient mental health expenditure by a state would yield an intersystem ROI of a quarter dollar for the jail system. There is significant cross-state variation in the intersystem ROI in both public inpatient and community mental health expenditures, and the ROI overall is greater for inpatient mental health spending than for community mental health spending.
[Mh] Termos MeSH primário: Investimentos em Saúde/estatística & dados numéricos
Serviços de Saúde Mental/economia
Prisões/estatística & dados numéricos
Saúde Pública/economia
[Mh] Termos MeSH secundário: Gastos em Saúde/tendências
Seres Humanos
Serviços de Saúde Mental/estatística & dados numéricos
Prisioneiros/psicologia
Prisioneiros/estatística & dados numéricos
Saúde Pública/estatística & dados numéricos
Análise de Regressão
Estados Unidos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180213
[Lr] Data última revisão:
180213
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161025
[St] Status:MEDLINE


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[PMID]:27771540
[Au] Autor:Lejarraga T; Woike JK; Hertwig R
[Ad] Endereço:Center for Adaptive Rationality, Max Planck Institute for Human Development, Berlin, Germany. Electronic address: lejarraga@mpib-berlin.mpg.de.
[Ti] Título:Description and experience: How experimental investors learn about booms and busts affects their financial risk taking.
[So] Source:Cognition;157:365-383, 2016 12.
[Is] ISSN:1873-7838
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:A few years ago, the world experienced the most severe economic crisis since the Great Depression. According to the depression baby hypothesis, people who live through such macroeconomic shocks take less financial risk in their future lives (e.g., lower stock market participation). This hypothesis has previously been tested against survey data. Here, we tested it in a simulated experimental stock market (based on the Spanish stock index, IBEX-35), varying both the length of historical data available to participants (including or excluding a macroeconomic shock) and the mode of learning about macroeconomic events (through sequential experience or symbolic descriptions). Investors who learned about the market from personal experience took less financial risk than did those who learned from graphs, thus echoing the description-experience gap observed in risky choice. In a second experiment, we reversed the market, turning the crisis into a boom. The description-experience gap persisted, with investors who experienced the boom taking more risk than those who did not. The results of a third experiment suggest that the observed gap is not driven by a wealth effect, and modeling suggests that the description-experience gap is explained by the fact that participants who learn from experience are more risk averse after a negative shock. Our findings highlight the crucial role of the mode of learning for financial risk taking and, by extension, in the legally required provision of financial advice.
[Mh] Termos MeSH primário: Tomada de Decisões
Investimentos em Saúde
Aprendizagem
Assunção de Riscos
[Mh] Termos MeSH secundário: Adulto
Feminino
Seres Humanos
Masculino
Risco
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1709
[Cu] Atualização por classe:180207
[Lr] Data última revisão:
180207
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161025
[St] Status:MEDLINE


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[PMID]:29240748
[Au] Autor:Nicholls G
[Ad] Endereço:Department of Medicine, University of Otago, Christchurch.
[Ti] Título:Funding public healthcare is an investment, not a cost.
[So] Source:N Z Med J;130(1467):95-96, 2017 12 15.
[Is] ISSN:1175-8716
[Cp] País de publicação:New Zealand
[La] Idioma:eng
[Mh] Termos MeSH primário: Custos e Análise de Custo
Investimentos em Saúde
[Mh] Termos MeSH secundário: Seres Humanos
[Pt] Tipo de publicação:LETTER; COMMENT
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180205
[Lr] Data última revisão:
180205
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171215
[St] Status:MEDLINE


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[PMID]:29240783
[Au] Autor:Li Y; Zheng B; Chen TT; Jiang XF
[Ad] Endereço:Department of Physics, Zhejiang University, Hangzhou 310027, P.R. China.
[Ti] Título:Fluctuation-driven price dynamics and investment strategies.
[So] Source:PLoS One;12(12):e0189274, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Investigation of the driven mechanism of the price dynamics in complex financial systems is important and challenging. In this paper, we propose an investment strategy to study how dynamic fluctuations drive the price movements. The strategy is successfully applied to different stock markets in the world, and the result indicates that the driving effect of the dynamic fluctuations is rather robust. We investigate how the strategy performance is influenced by the market states and optimize the strategy performance by introducing two parameters. The strategy is also compared with several typical technical trading rules. Our findings not only provide an investment strategy which extends investors' profits, but also offer a useful method to look into the dynamic properties of complex financial systems.
[Mh] Termos MeSH primário: Investimentos em Saúde
[Mh] Termos MeSH secundário: Modelos Econômicos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180116
[Lr] Data última revisão:
180116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171215
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0189274


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[PMID]:29231030
[Au] Autor:Levin RP
[Ti] Título:Opportunities and Challenges of a Small Group Practice.
[So] Source:Dent Today;36(6):8, 10, 2017 Jun.
[Is] ISSN:8750-2186
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Prática Odontológica de Grupo/organização & administração
Administração da Prática Odontológica/organização & administração
[Mh] Termos MeSH secundário: Mobilidade Ocupacional
Competição Econômica
Seres Humanos
Investimentos em Saúde
Liderança
Técnicas de Planejamento
Salários e Benefícios
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180115
[Lr] Data última revisão:
180115
[Sb] Subgrupo de revista:D
[Da] Data de entrada para processamento:171213
[St] Status:MEDLINE


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[PMID]:29215235
[Au] Autor:Greenwald L; Copeland C; VanDerhei J
[Ti] Título:The 2017 Retirement Confidence Survey: Many Workers Lack Retirement Confidence and Feel Stressed About Retirement Preparations.
[So] Source:EBRI Issue Brief;(431):1-29, 2017 03 21.
[Is] ISSN:0887-137X
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Emprego/estatística & dados numéricos
Aposentadoria/economia
Aposentadoria/psicologia
Autoeficácia
[Mh] Termos MeSH secundário: Adulto
Idoso
Coleta de Dados/métodos
Feminino
Financiamento Pessoal/estatística & dados numéricos
Seres Humanos
Renda/estatística & dados numéricos
Inflação
Entrevistas como Assunto
Investimentos em Saúde/estatística & dados numéricos
Masculino
Meia-Idade
Pensões/estatística & dados numéricos
Previdência Social/estatística & dados numéricos
Estados Unidos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180108
[Lr] Data última revisão:
180108
[Sb] Subgrupo de revista:H
[Da] Data de entrada para processamento:171208
[St] Status:MEDLINE


  10 / 7694 MEDLINE  
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[PMID]:29215234
[Au] Autor:Banerjee S
[Ti] Título:How Does the Level of Household Savings Affect Preference for Immediate Annuities?
[So] Source:EBRI Issue Brief;(430):1-17, 2017 02 08.
[Is] ISSN:0887-137X
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Financiamento Pessoal/economia
Investimentos em Saúde/economia
Pensões
Aposentadoria/economia
[Mh] Termos MeSH secundário: Seres Humanos
Renda/estatística & dados numéricos
Expectativa de Vida
Previdência Social
Estados Unidos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180108
[Lr] Data última revisão:
180108
[Sb] Subgrupo de revista:H
[Da] Data de entrada para processamento:171208
[St] Status:MEDLINE



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