Base de dados : MEDLINE
Pesquisa : N03.540.052 [Categoria DeCS]
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[PMID]:29428031
[Au] Autor:Rosati CM; Gaudino M; Vardas PN; Weber DJ; Blitzer D; Hameedi F; Koniaris LG; Girardi LN
[Ti] Título:Academic Clinical Productivity of Cardiac Surgeons in the State of New York: Who Publishes More and Who Operates More.
[So] Source:Am Surg;84(1):71-79, 2018 Jan 01.
[Is] ISSN:1555-9823
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:We investigated whether/how cardiac surgeons can be productive both academically and clinically. Using online resources (New York State Adult Cardiac Surgery database, SCOPUS), we collected individual clinical volumes (operations performed/year), academic metrics (ongoing publications, role as author), practice setting, and seniority for all cardiac surgeons in the State of New York from 1994 to 2011. Over time, individual clinical volumes decreased (median operations/year: 193 in 1995 vs 126 in 2010; P < 0.001), whereas academic productivity remained unchanged (median publications/year: 0.7 vs 0.3; P = 0.55). There was no correlation (Spearman's correlation coefficient: -0.061; P = 0.08) between the number of new publications and operations/year for the whole population. More operations/year (median: 155 vs 144; P = 0.03) were performed by surgeons without versus with publications during that same year. Who published more worked at hospitals with higher clinical volumes (Spearman's correlation coefficient: 0.16; P < 0.001) and was more likely affiliated with thoracic surgery fellowship programs (median publications/year: 1.7 for affiliated vs 0 for nonaffiliated surgeons; P < 0.001). Cardiac surgeons could be classified into four categories: ∼40 per cent clinically busy, but not publishing at all; ∼45 per cent operating less, but publishing a little; ∼15 per cent clinically very productive (operating as much as the nonpublishers) and publishing a lot; and ∼1 per cent operating the least, but publishing the most.
[Mh] Termos MeSH primário: Academias e Institutos
Eficiência
Transplante de Coração/estatística & dados numéricos
Hospitais Universitários/estatística & dados numéricos
Editoração/estatística & dados numéricos
Cirurgia Torácica/recursos humanos
Cirurgia Torácica/estatística & dados numéricos
[Mh] Termos MeSH secundário: Adulto
Procedimentos Cirúrgicos Cardíacos/estatística & dados numéricos
Bases de Dados Factuais
Hospitais/estatística & dados numéricos
Seres Humanos
New York
Procedimentos Cirúrgicos Torácicos/estatística & dados numéricos
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180301
[Lr] Data última revisão:
180301
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180212
[St] Status:MEDLINE


  2 / 13100 MEDLINE  
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[PMID]:29368466
[Au] Autor:Lombardo PA
[Ti] Título:Anthropometry, Race, and Eugenic Research: "Measurements of Growing Negro Children" at the Tuskegee Institute, 1932­1944.
[So] Source:Clio Med;95:215-39, 2016.
[Is] ISSN:0045-7183
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Mh] Termos MeSH primário: Afroamericanos/história
Antropometria/história
Eugenia (Ciência)/história
Experimentação Humana/história
[Mh] Termos MeSH secundário: Academias e Institutos/história
Alabama
Criança
História do Século XX
Seres Humanos
Sífilis/história
Estados Unidos
United States Public Health Service
[Pt] Tipo de publicação:HISTORICAL ARTICLE; JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180215
[Lr] Data última revisão:
180215
[Sb] Subgrupo de revista:IM; QIS
[Da] Data de entrada para processamento:180126
[St] Status:MEDLINE


  3 / 13100 MEDLINE  
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[PMID]:29338019
[Au] Autor:Meyers LC; Brown AM; Moneta-Koehler L; Chalkley R
[Ad] Endereço:Office for Biomedical Research Education and Training, School of Medicine, Vanderbilt University, Nashville, Tennessee, United States of America.
[Ti] Título:Survey of checkpoints along the pathway to diverse biomedical research faculty.
[So] Source:PLoS One;13(1):e0190606, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:There is a persistent shortage of underrepresented minority (URM) faculty who are involved in basic biomedical research at medical schools. We examined the entire training pathway of potential candidates to identify the points of greatest loss. Using a range of recent national data sources, including the National Science Foundation's Survey of Earned Doctorates and Survey of Doctoral Recipients, we analyzed the demographics of the population of interest, specifically those from URM backgrounds with an interest in biomedical sciences. We examined the URM population from high school graduates through undergraduate, graduate, and postdoctoral training as well as the URM population in basic science tenure track faculty positions at medical schools. We find that URM and non-URM trainees are equally likely to transition into doctoral programs, to receive their doctoral degree, and to secure a postdoctoral position. However, the analysis reveals that the diversions from developing a faculty career are found primarily at two clearly identifiable places, specifically during undergraduate education and in transition from postdoctoral fellowship to tenure track faculty in the basic sciences at medical schools. We suggest focusing additional interventions on these two stages along the educational pathway.
[Mh] Termos MeSH primário: Academias e Institutos/organização & administração
Pesquisa Biomédica
Diversidade Cultural
Docentes/estatística & dados numéricos
Grupos Minoritários/estatística & dados numéricos
[Mh] Termos MeSH secundário: Biologia/educação
Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180215
[Lr] Data última revisão:
180215
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180117
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0190606


  4 / 13100 MEDLINE  
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[PMID]:27562960
[Au] Autor:DiBartolo PM; Gregg-Jolly L; Gross D; Manduca CA; Iverson E; Cooke DB; Davis GK; Davidson C; Hertz PE; Hibbard L; Ireland SK; Mader C; Pai A; Raps S; Siwicki K; Swartz JE
[Ad] Endereço:Clark Science Center, Smith College, Northampton, MA 01063 pdibarto@smith.edu.
[Ti] Título:Principles and Practices Fostering Inclusive Excellence: Lessons from the Howard Hughes Medical Institute's Capstone Institutions.
[So] Source:CBE Life Sci Educ;15(3), 2016.
[Is] ISSN:1931-7913
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Best-practices pedagogy in science, technology, engineering, and mathematics (STEM) aims for inclusive excellence that fosters student persistence. This paper describes principles of inclusivity across 11 primarily undergraduate institutions designated as Capstone Awardees in Howard Hughes Medical Institute's (HHMI) 2012 competition. The Capstones represent a range of institutional missions, student profiles, and geographical locations. Each successfully directed activities toward persistence of STEM students, especially those from traditionally underrepresented groups, through a set of common elements: mentoring programs to build community; research experiences to strengthen scientific skill/identity; attention to quantitative skills; and outreach/bridge programs to broaden the student pool. This paper grounds these program elements in learning theory, emphasizing their essential principles with examples of how they were implemented within institutional contexts. We also describe common assessment approaches that in many cases informed programming and created traction for stakeholder buy-in. The lessons learned from our shared experiences in pursuit of inclusive excellence, including the resources housed on our companion website, can inform others' efforts to increase access to and persistence in STEM in higher education.
[Mh] Termos MeSH primário: Academias e Institutos
Educação de Pós-Graduação
[Mh] Termos MeSH secundário: Relações Comunidade-Instituição
Avaliação Educacional
Engenharia/educação
Seres Humanos
Matemática/educação
Desenvolvimento de Programas
Ciência/educação
Estudantes
Tecnologia/educação
Pensamento
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1702
[Cu] Atualização por classe:180127
[Lr] Data última revisão:
180127
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160827
[St] Status:MEDLINE


  5 / 13100 MEDLINE  
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[PMID]:29236394
[Au] Autor:Vynogradova RP; Danilova VM; Yurasova SP
[Ti] Título:[Scientific and practical activity of the Department of Muscle Biochemistry of the Palladin Institute of Biochemistry of NAS of Ukraine].
[So] Source:Ukr Biochem J;89(1):90-101, 2017 Jan-Dec.
[Is] ISSN:2409-4943
[Cp] País de publicação:Ukraine
[La] Idioma:rus; ukr
[Ab] Resumo:The article focuses on scientific and practical activity of the Department of Muscle Biochemistry of the Palladin Institute of Biochemistry of NAS of Ukraine in the context of its foundation and development. Main findings and practical achievements in the area of muscle biochemistry are summarized and discussed.
[Mh] Termos MeSH primário: Academias e Institutos/história
Bioquímica/história
Músculos/metabolismo
[Mh] Termos MeSH secundário: Bioquímica/recursos humanos
História do Século XX
História do Século XXI
Seres Humanos
Ucrânia
[Pt] Tipo de publicação:HISTORICAL ARTICLE; JOURNAL ARTICLE; PORTRAITS
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180116
[Lr] Data última revisão:
180116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171214
[St] Status:MEDLINE
[do] DOI:10.15407/ubj89.01.090


  6 / 13100 MEDLINE  
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[PMID]:29236382
[Au] Autor:Danilova VM; Vynogradova RP; Chernysh IG; Petrenko TM
[Ti] Título:[Inventive activity of the Department of Metabolism Regulation of the Palladin Institute of Biochemistry of NAS of Ukraine].
[So] Source:Ukr Biochem J;88(6):110-21, 2016 Nov-Dec.
[Is] ISSN:2409-4943
[Cp] País de publicação:Ukraine
[La] Idioma:rus; ukr
[Ab] Resumo:The article is devoted to the inventive activity of the Department of Metabolism Regulation of the Palladin Institute of Biochemistry of NAS of Ukraine in the context of the history of its inception, development and the research activities of its founder, academician of NAS of Ukraine M. F. Guly as well as his students and followers. It briefly tells about practical achievements of M. F. Guly which were as significant, immense and diverse as his scientific accomplishments. The paper analyses in detail the practical results of scientific research of his students and followers aimed to solve practical problems of medicine, food-processing, agriculture, and which are essentially a continuation of the ideas and projects of M. F. Guly.
[Mh] Termos MeSH primário: Academias e Institutos/história
Bioquímica/história
Invenções/história
[Mh] Termos MeSH secundário: Bioquímica/recursos humanos
História do Século XX
História do Século XXI
Ucrânia
[Pt] Tipo de publicação:HISTORICAL ARTICLE; JOURNAL ARTICLE; PORTRAITS
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180116
[Lr] Data última revisão:
180116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171214
[St] Status:MEDLINE
[do] DOI:10.15407/ubj88.06.110


  7 / 13100 MEDLINE  
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[PMID]:29235825
[Au] Autor:Danilova VM; Vynogradova RP; Torkhova SG
[Ti] Título:[Inventive activity of the Department of Molecular Immunology of the Palladin Institute of Biochemistry of NAS of Ukraine].
[So] Source:Ukr Biochem J;88(5):116-35, 2016 Sep-Oct.
[Is] ISSN:2409-4943
[Cp] País de publicação:Ukraine
[La] Idioma:rus; ukr
[Ab] Resumo:The article is devoted to the inventive activity of the Department of Molecular Immunology of the Palladin Institute of Biochemistry of NAS of Ukraine in the context of the history of its inception, development and in the context of scholarly and organizational activities of Sergii Vasyl'ovych Komisarenko. This autumn marks 50th anniversary since young Sergii Komisarenko (now ­ Academician of NAS and NAMS of Ukraine, Dr. Biol. Sci., Professor) has joined the Palladin Institute of Biochemistry, has completed all stages of the academic carrier from PhD student to Head of the Institute. He is the first in Ukraine who started the new branch of research ­ molecular immunology, created a strong scientific school, which earned worldwide acclaim and made significant contribution to finding solutions to current problems in human health sciences. S.V. Komisarenko was among those, who were first in the USSR to use immunoenzyme and flow cytofluometric assays, hybridoma technology for producing monoclonal antibodies and immunochemical assay of proteins, which became the basis for development of highly sensitive and highly specific immunodiagnostic systems, which are of high necessity in medicine, veterinary, development of immunotechnologies, environment monitoring, etc. Under his leadership the Department has made a series of important discoveries and developments including relating to antitumour immunotoxins, effects of low dose radiation on the immune system of Chernobyl liquidators, immunochemical structure of neurotoxin apamine, cytochrom c, fibrinogen and fibrin molecules at different stages of polymerization, diphtheria toxin and its receptor, tuberculosis causing micobacterium, roles of protease-activated receptors (PARs) and nicotinic acetylcholine receptors of lymphocytes, nature of polyreactive immunoglobulins (PRIGs), among other important scientific contributions. S.V. Komisarenko and his colleagues also hold numerous (more than 80) author's certificates and patents in Ukraine and USSR.
[Mh] Termos MeSH primário: Academias e Institutos/história
Alergia e Imunologia/história
Bioquímica/história
Invenções/história
[Mh] Termos MeSH secundário: Alergia e Imunologia/recursos humanos
Bioquímica/recursos humanos
História do Século XX
História do Século XXI
Seres Humanos
Imunoglobulinas/análise
Ucrânia
[Pt] Tipo de publicação:HISTORICAL ARTICLE; JOURNAL ARTICLE; PORTRAITS
[Nm] Nome de substância:
0 (Immunoglobulins)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180116
[Lr] Data última revisão:
180116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171214
[St] Status:MEDLINE
[do] DOI:10.15407/ubj88.05.116


  8 / 13100 MEDLINE  
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[PMID]:29235792
[Au] Autor:Danilova VM; Vynogradova RP; Chernysh IY
[Ti] Título:[Inventive activity of the Departments of Chemistry and Biochemistry of Enzymes, and Protein Structure and Function of the Palladin Institute of Biochemistry of NAS of Ukraine. Part III. Diagnostic test-systems for analysis of fibrinolysis blood system and novel approaches to thrombosis treatment].
[So] Source:Ukr Biochem J;88(4):129-37, 2016 Jul-Aug.
[Is] ISSN:2409-4943
[Cp] País de publicação:Ukraine
[La] Idioma:rus; ukr
[Ab] Resumo:This article continues analysis of scientific achievements of the Institute of Biochemistry in the study of hemostasis system. Two previous articles were focused on the studies of blood coagulation proteins and development of the immune-enzyme test-systems for evaluation of the risk of thrombosis upon various pathologies. This article highlights the research on the blood fibrinolysis system and new approaches to thrombosis treatment, which were developed (and are under development) in the Palladin Institute of Biochemistry of the NAS of Ukraine, in particular, in the Department of Chemistry and Biochemistry of Enzymes headed previously by Dr.Sci.(Biol.) S. O. Kudinov and now by Dr.Sci.(Biol.) T .V. Grinenko, and also in the Department of Protein Structure and Function headed by Dr.Biol.Sci. E. M. Makogonenko. The fundamental knowledge of protein molecule functions and mechanisms of regulation of blood coagulation and fibrinolysis opens up new opportunities to diagnose hemostasis disorders and control the effectiveness of the cardiovascular disease treatment and also contributes to development of new techniques for isolation of new proteins ­ promising therapeutic agents.
[Mh] Termos MeSH primário: Academias e Institutos/história
Bioquímica/história
Transtornos da Coagulação Sanguínea/diagnóstico
Testes Diagnósticos de Rotina/história
Invenções/história
[Mh] Termos MeSH secundário: Bioquímica/recursos humanos
Transtornos da Coagulação Sanguínea/história
Fibrinólise/fisiologia
História do Século XX
História do Século XXI
Seres Humanos
Ucrânia
[Pt] Tipo de publicação:HISTORICAL ARTICLE; JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180116
[Lr] Data última revisão:
180116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171214
[St] Status:MEDLINE
[do] DOI:10.15407/ubj88.04.129


  9 / 13100 MEDLINE  
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[PMID]:29235336
[Au] Autor:Lugovska NE
[Ti] Título:[Inventive activity of the Departments of Protein Structure and Function, and Molecular Immunology of the Palladin Institute of Biochemistry of NAS of Ukraine. Part II. National breakthrough in the study and diagnostics of human hemostasis system].
[So] Source:Ukr Biochem J;88(3):106-18, 2016 May-Jun.
[Is] ISSN:2409-4943
[Cp] País de publicação:Ukraine
[La] Idioma:rus; ukr
[Ab] Resumo:The scientists of Protein Structure and Function, and Molecular Immunology Departments of the Palladin Institute of Biochemistry (NAS of Ukraine) under the supervision of member of NASU and NAMSU, prof. S. V. Komisarenko and corresponding member of NASU prof. E. V. Lugovskoy have made the real breakthrough in the field of research of the mechanisms of fibrin polymerization and formation of fibrin framework of thrombi. The immunodiagnostic test-systems for the evaluation of the risk of thrombus formation were developed for the first time. Researches have obtained the monoclonal antibodies to fibrinogen, fibrin, D-dimer and their fragments. These monoclonal antibodies were used as molecular probes for the localization of newly detected fibrin polymerization sites. Obtained antibodies with high affinity interact with fibrinogen, D-dimer and soluble fibrin ­ main markers of the risk of thrombus formation. They were used for the development of the immunodiagnostic test-systems to quantify these markers in human blood plasma for the evaluation of the state of haemostasis system, detection of prethrombotic states, disseminated intravascular coagulation, detection of thrombosis and monitoring of antithrombotic and fibrinolytic therapy. The successful trial of developed test-systems was carried out in clinics of Ukraine, and the State registration was obtained for the implementation of them into the clinical practice. Presented works were awarded State prize of Ukraine in Science and technology.
[Mh] Termos MeSH primário: Academias e Institutos/história
Alergia e Imunologia/história
Bioquímica/história
Transtornos da Coagulação Sanguínea/diagnóstico
Invenções/história
[Mh] Termos MeSH secundário: Alergia e Imunologia/recursos humanos
Bioquímica/recursos humanos
Transtornos da Coagulação Sanguínea/história
História do Século XX
História do Século XXI
Seres Humanos
Ucrânia
[Pt] Tipo de publicação:HISTORICAL ARTICLE; JOURNAL ARTICLE; PORTRAITS
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180116
[Lr] Data última revisão:
180116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171214
[St] Status:MEDLINE
[do] DOI:10.15407/ubj88.03.106


  10 / 13100 MEDLINE  
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[PMID]:29227613
[Au] Autor:Danilova LD; Vynogradova RP; Grigorieva MV
[Ti] Título:[Inventive activity of the Department of Protein Structure and Function of the Palladin Institute of Biochemistry of NAS of Ukraine. Part I. Development of the diagnostic methods for detection of hemostasis disorders and characterization of certain blood coagulation factors].
[So] Source:Ukr Biochem J;88(2):107-18, 2016 Mar-Apr.
[Is] ISSN:2409-4943
[Cp] País de publicação:Ukraine
[La] Idioma:rus; ukr
[Mh] Termos MeSH primário: Academias e Institutos/história
Bioquímica/história
Transtornos Herdados da Coagulação Sanguínea/diagnóstico
Invenções/história
[Mh] Termos MeSH secundário: Bioquímica/recursos humanos
Transtornos Herdados da Coagulação Sanguínea/história
Fatores de Coagulação Sanguínea/história
Fatores de Coagulação Sanguínea/metabolismo
Fatores de Coagulação Sanguínea/ultraestrutura
História do Século XX
História do Século XXI
Seres Humanos
Ucrânia
[Pt] Tipo de publicação:HISTORICAL ARTICLE; JOURNAL ARTICLE; PORTRAITS
[Nm] Nome de substância:
0 (Blood Coagulation Factors)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180116
[Lr] Data última revisão:
180116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171212
[St] Status:MEDLINE
[do] DOI:10.15407/ubj88.02.107



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