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[PMID]:29233812
[Au] Autor:Iacobucci G
[Ad] Endereço:The BMJ.
[Ti] Título:Proposals for opt-out organ donation launched for England.
[So] Source:BMJ;359:j5764, 2017 12 12.
[Is] ISSN:1756-1833
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Legislação Médica/ética
Obtenção de Tecidos e Órgãos/legislação & jurisprudência
[Mh] Termos MeSH secundário: Inglaterra/epidemiologia
Conhecimentos, Atitudes e Prática em Saúde
Seres Humanos
Opinião Pública
Obtenção de Tecidos e Órgãos/estatística & dados numéricos
Estados Unidos
United States Dept. of Health and Human Services
[Pt] Tipo de publicação:NEWS
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180223
[Lr] Data última revisão:
180223
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171214
[St] Status:MEDLINE
[do] DOI:10.1136/bmj.j5764


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[PMID]:28426307
[Au] Autor:Petrillo LA; Dzeng E; Harrison KL; Forbes L; Scribner B; Koenig BA
[Ad] Endereço:Laura A. Petrillo is with the Division of Geriatrics, University of California, San Francisco (UCSF), and San Francisco Veterans Affairs. Elizabeth Dzeng is with the Division of Hospital Medicine, UCSF, and UCSF Bioethics. Krista L. Harrison is with the Division of Geriatrics, UCSF. Lindsay Forbes a
[Ti] Título:How California Prepared for Implementation of Physician-Assisted Death: A Primer.
[So] Source:Am J Public Health;107(6):883-888, 2017 Jun.
[Is] ISSN:1541-0048
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Physician-assisted death is now legal in California, and similar laws are being considered in many other states. The California law includes safeguards, yet health care providers will face practical and ethical issues while implementing physician-assisted death that are not addressed by the law. To help providers and health care facilities in California prepare to provide optimal care to patients who inquire about physician-assisted death, we brought together experts from California, Oregon, and Washington. We convened a conference of 112 stakeholders in December 2015, and herein present their recommendations. Themes of recommendations regarding implementation include (1) institutions should develop and revise physician-assisted death policies; (2) legal physician-assisted death will have implications for California's culturally and socioeconomically diverse population, and for patients from vulnerable groups; (3) conscientious objection and moral distress for health care providers must be considered; and (4) palliative care is essential to the response to the law. The expert conference participants' insights are a valuable guide, both for providers and health care facilities in California planning or revising their response, and for other jurisdictions where physician-assisted death laws are being considered or implemented.
[Mh] Termos MeSH primário: Eutanásia/legislação & jurisprudência
Médicos
Guias de Prática Clínica como Assunto
Suicídio Assistido/legislação & jurisprudência
[Mh] Termos MeSH secundário: Atitude do Pessoal de Saúde
California
Eutanásia/ética
Seres Humanos
Legislação Médica/ética
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1706
[Cu] Atualização por classe:171013
[Lr] Data última revisão:
171013
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170421
[St] Status:MEDLINE
[do] DOI:10.2105/AJPH.2017.303755


  3 / 14972 MEDLINE  
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[PMID]:28383385
[Au] Autor:Farrell RM; Mabel H; Reider MW; Coleridge M; Yoder Katsuki M
[Ad] Endereço:Department of Obstetrics and Gynecology and Women's Health Institute, the Department of Bioethics, and the Genomic Medicine Institute, Cleveland Clinic, Cleveland, Ohio.
[Ti] Título:Implications of Ohio's 20-Week Abortion Ban on Prenatal Patients and the Assessment of Fetal Anomalies.
[So] Source:Obstet Gynecol;129(5):795-799, 2017 May.
[Is] ISSN:1873-233X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Ohio's governor recently signed into law Senate Bill 127, a bill that makes it a fourth-degree felony for a health care provider to perform an abortion "when the probable post-fertilization age of the unborn child is 20 weeks or greater," joining a series of other states that have enacted such legislation or are moving toward similar legislation. Twenty-week bans have salient implications for women's health, quality of care, and access to services, particularly in the context of the delivery of prenatal care. Because of the timeline of the initiation of prenatal care and assessments of fetal genetic and anatomic anomalies, patients may increasingly find themselves at or near the 20-week postfertilization gestational threshold when they have insufficient information to decide about continuing or ending the pregnancy. This law thus leaves women and families with limited time to obtain a genetic or anatomic diagnosis, restricts access to abortion care at a crucial decision-making time in the pregnancy, and has significant implications for the patient-physician relationship. This law also has ramifications for women and health care providers outside of Ohio, because patients who have made the choice to end a pregnancy will have to cross state lines for abortion care. It is important for obstetric providers to be aware of the ramifications of 20-week bans and take steps to ensure that pregnant women receive high-quality care despite the burdens imposed on the health care decision-making process.
[Mh] Termos MeSH primário: Aborto Induzido/legislação & jurisprudência
Feto/anormalidades
[Mh] Termos MeSH secundário: Feminino
Regulamentação Governamental
Seres Humanos
Legislação Médica
Ohio
Gravidez
Segundo Trimestre da Gravidez
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170713
[Lr] Data última revisão:
170713
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170407
[St] Status:MEDLINE
[do] DOI:10.1097/AOG.0000000000001996


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[PMID]:28372273
[Au] Autor:Ferry N
[Ad] Endereço:Département de thérapie cellulaire, Hôpital Saint Louis, 1 Avenue Claude Vellefaux, 75010 Paris, France. E-mail: Nferry57@gmail.com.
[Ti] Título:European regulation for therapeutic use of stem cells.
[So] Source:Biomed Mater Eng;28(s1):S3-S7, 2017.
[Is] ISSN:1878-3619
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:The regulation for the use of stem cells has evolved during the past decade with the aim of ensuring a high standard of quality and safety for human derived products throughout Europe to comply with the provision of the Lisbon treaty. To this end, new regulations have been issued and the regulatory status of stem cells has been revised. Indeed, stem cells used for therapeutic purposes can now be classified as a cell preparation, or as advanced therapy medicinal products depending on the clinical indication and on the procedure of cell preparation. Furthermore, exemptions to the European regulation are applicable for stem cells prepared and used within the hospital. The aim of this review is to give the non-specialized reader a broad overview of this particular regulatory landscape.
[Mh] Termos MeSH primário: Terapia Baseada em Transplante de Células e Tecidos
Legislação Médica
Transplante de Células-Tronco/legislação & jurisprudência
Células-Tronco
Engenharia Tecidual
[Mh] Termos MeSH secundário: Terapia Baseada em Transplante de Células e Tecidos/normas
Ensaios Clínicos como Assunto
Europa (Continente)
União Europeia
Seres Humanos
Legislação Médica/normas
Controle de Qualidade
Transplante de Células-Tronco/normas
Células-Tronco/classificação
Células-Tronco/citologia
Engenharia Tecidual/normas
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170717
[Lr] Data última revisão:
170717
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170405
[St] Status:MEDLINE
[do] DOI:10.3233/BME-171619


  5 / 14972 MEDLINE  
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[PMID]:28328335
[Au] Autor:Chaiyachati KH; Asch DA; Grande DT
[Ad] Endereço:From the Robert Wood Johnson Foundation Clinical Scholars Program, University of Pennsylvania (K.H.C., D.A.A., D.T.G.), and the Cpl. Michael J. Crescent Veterans Affairs Medical Center (K.H.C., D.A.A.) - both in Philadelphia.
[Ti] Título:Patient Inducements - High Graft or High Value?
[So] Source:N Engl J Med;376(12):1107-1109, 2017 Mar 23.
[Is] ISSN:1533-4406
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Assistência à Saúde/economia
Legislação Médica
Motivação
[Mh] Termos MeSH secundário: Leis Antitruste
Assistência à Saúde/legislação & jurisprudência
Seres Humanos
Pacientes
Estados Unidos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170428
[Lr] Data última revisão:
170428
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170323
[St] Status:MEDLINE
[do] DOI:10.1056/NEJMp1613274


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[PMID]:28255379
[Au] Autor:Pituru SM; Nanu A; Bucur A
[Ad] Endereço:Discipline of Work Organization and Legislation in Dentistry, "Carol Davila" University of Medicine and Pharmacy, School of Dentistry, Bucharest, Romania.
[Ti] Título:Medical legislation - educational needs assessment for dental students.
[So] Source:J Med Life;10(1):56-59, 2017 Jan-Mar.
[Is] ISSN:1844-3117
[Cp] País de publicação:Romania
[La] Idioma:eng
[Ab] Resumo:: Many studies have highlighted the vulnerabilities in medical practice due to the legislation ignorance. Therefore, developing special programs for students training is needed and has become imperative. : This research aimed to identify the educational needs for the 5th year students in "Carol Davila" School of Dentistry in Bucharest, related to the legislation in dentistry and its area of application. : 199 students were invited to respond to a specially designed questionnaire. The questionnaire had 11 closed-response questions and the answers were statistically analyzed. The results indicated many educational needs in all the areas of investigation. : "Carol Davila" University of Medicine and Pharmacy is the first university in Romania that created a new discipline in the School of Dentistry, called Work Organization and Legislation in Medicine and Dentistry.
[Mh] Termos MeSH primário: Educação em Odontologia/legislação & jurisprudência
Legislação Médica
Determinação de Necessidades de Cuidados de Saúde
Estudantes de Odontologia/legislação & jurisprudência
Estudantes de Medicina
[Mh] Termos MeSH secundário: Seres Humanos
Romênia
Inquéritos e Questionários
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170501
[Lr] Data última revisão:
170501
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170304
[St] Status:MEDLINE


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[PMID]:28249945
[Au] Autor:Corrigan P; Schomerus G; Smelson D
[Ad] Endereço:Patrick Corrigan, PsyD, Illinois Institute of Technology, Chicago, Illinois, USA; Georg Schomerus, MD, PhD, Department of Psychiatry, Greifswald University, Greifswald, Germany; David Smelson, PsyD, University of Massachusetts Medical School, Worcester, Massachusetts, USA corrigan@iit.edu.
[Ti] Título:Are some of the stigmas of addictions culturally sanctioned?
[So] Source:Br J Psychiatry;210(3):180-181, 2017 Mar.
[Is] ISSN:1472-1465
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:We provide three examples of how addiction stigma is sanctioned: (a) discrimination against people with addictions is often legal; (b) public health communications frequently use stigma to promote prevention; (c) some programmes, such as '12 steps' promote self-stigma. The implications of sanctioned stigma for stigma-change programmes are then discussed.
[Mh] Termos MeSH primário: Estigma Social
Transtornos Relacionados ao Uso de Substâncias
[Mh] Termos MeSH secundário: Cultura
Seres Humanos
Legislação Médica
[Pt] Tipo de publicação:EDITORIAL
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170904
[Lr] Data última revisão:
170904
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170303
[St] Status:MEDLINE
[do] DOI:10.1192/bjp.bp.116.185421


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[PMID]:28220723
[Au] Autor:Briers N; Dempers JJ
[Ad] Endereço:1 Stellenbosch University, South Africa.
[Ti] Título:Ethical Issues Surrounding the Use of Modern Human Remains for Research in South Africa.
[So] Source:J Empir Res Hum Res Ethics;12(1):45-54, 2017 Feb.
[Is] ISSN:1556-2654
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Chapter 8 of the South African National Health Act 61 of 2003 (NHA) that deals with the donation of human tissue was promulgated in 2012. The new Act is perceived to impose restrictions on low-risk research involving human remains. This study aimed to identify the issues raised by a research ethics committee (REC) when reviewing protocols where human remains are used as data source. REC minutes from 2009 to 2014 were reviewed, and issues raised by the committee were categorized. In total, 127 protocols submitted to the committee over 6 years involved human remains. Queries relating to science (22.2%) and administration (18.9%) were the most common, whereas queries relating to legal issues constituted only 10.2%. Ethical issues centered on informed consent regarding sensitive topics such as HIV, DNA, and deceased children. The change in legislation did not change the number or type of legal issues identified by the REC.
[Mh] Termos MeSH primário: Temas Bioéticos
Pesquisa Biomédica/ética
Restos Mortais
Revisão Ética
Comitês de Ética em Pesquisa
Legislação Médica
Obtenção de Tecidos e Órgãos/ética
[Mh] Termos MeSH secundário: Pesquisa Biomédica/legislação & jurisprudência
Criança
DNA
Ética em Pesquisa
Infecções por HIV
Seres Humanos
Consentimento Livre e Esclarecido
África do Sul
Obtenção de Tecidos e Órgãos/legislação & jurisprudência
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
9007-49-2 (DNA)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171102
[Lr] Data última revisão:
171102
[Sb] Subgrupo de revista:E; IM
[Da] Data de entrada para processamento:170222
[St] Status:MEDLINE
[do] DOI:10.1177/1556264616688973


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[PMID]:28182596
[Au] Autor:Ahmed R; Lopez J; Bae S; Massie AB; Chow EK; Chopra K; Orandi BJ; Lonze BE; May JW; Sacks JM; Segev DL
[Ad] Endereço:From the Departments of *Surgery, and †Plastic and Reconstructive Surgery, Johns Hopkins School of Medicine; ‡Department of Epidemiology, Johns Hopkins School of Public Health, Baltimore, MD; and §Division of Plastic Surgery, Department of Surgery, Massachusetts General Hospital, Boston, MA.
[Ti] Título:The Dawn of Transparency: Insights from the Physician Payment Sunshine Act in Plastic Surgery.
[So] Source:Ann Plast Surg;78(3):315-323, 2017 Mar.
[Is] ISSN:1536-3708
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The Physician Payments Sunshine Act (PSSA) is a government initiative that requires all biomedical companies to publicly disclose payments to physicians through the Open Payments Program (OPP). The goal of this study was to use the OPP database and evaluate all nonresearch-related financial transactions between plastic surgeons and biomedical companies. METHODS: Using the first wave of OPP data published on September 30, 2014, we studied the national distribution of industry payments made to plastic surgeons during a 5-month period. We explored whether a plastic surgeon's scientific productivity (as determined by their h-index), practice setting (private versus academic), geographic location, and subspecialty were associated with payment amount. RESULTS: Plastic surgeons (N = 4195) received a total of US $5,278,613. The median (IQR) payment to a plastic surgeon was US $115 (US $35-298); mean, US $158. The largest payment to an individual was US $341,384. The largest payment category was non-CEP speaker fees (US $1,709,930) followed by consulting fees (US $1,403,770). Plastic surgeons in private practice received higher payments per surgeon compared with surgeons in academic practice (median [IQR], US $165 [US $81-$441] vs median [IQR], US $112 [US $33-$291], rank-sum P < 0.001). Among academic plastic surgeons, a higher h-index was associated with 77% greater chance of receiving at least US $1000 in total payments (RR/10 unit h-index increase = 1.47 1.772.11, P < 0.001). This association was not seen among plastic surgeons in private practice (RR = 0.89 1.091.32, P < 0.4). CONCLUSIONS: Plastic surgeons in private practice receive higher payments from industry. Among academic plastic surgeons, higher payments were associated with higher h-indices.
[Mh] Termos MeSH primário: Conflito de Interesses/legislação & jurisprudência
Revelação/legislação & jurisprudência
Indústria Farmacêutica/legislação & jurisprudência
Apoio Financeiro
Legislação Médica
Cirurgiões/legislação & jurisprudência
Cirurgia Plástica/legislação & jurisprudência
[Mh] Termos MeSH secundário: Conflito de Interesses/economia
Bases de Dados Factuais
Revelação/estatística & dados numéricos
Indústria Farmacêutica/economia
Doações
Setor de Assistência à Saúde/economia
Setor de Assistência à Saúde/legislação & jurisprudência
Seres Humanos
Cirurgiões/economia
Cirurgiões/estatística & dados numéricos
Cirurgia Plástica/economia
Estados Unidos
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170224
[Lr] Data última revisão:
170224
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170210
[St] Status:MEDLINE
[do] DOI:10.1097/SAP.0000000000000874


  10 / 14972 MEDLINE  
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[PMID]:28182270
[Au] Autor:Jarow JP
[Ad] Endereço:Center for Drug Evaluation and Research, U.S. FDA, Silver Spring, Maryland, USA.
[Ti] Título:Use of External Controls in Regulatory Decision-Making.
[So] Source:Clin Pharmacol Ther;101(5):595-596, 2017 May.
[Is] ISSN:1532-6535
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The expanded use of electronic data retrieval systems has greatly expanded the potential sources of real-world data and presents new opportunities for evidence generation outside of the traditional research trial. These data may be used to inform trial design and interpretation as well. Externally controlled trials, such as single-arm and noninferiority designs, have long been used in regulatory decision-making despite the potential flaws based on assumptions of assay sensitivity and constancy.
[Mh] Termos MeSH primário: Ensaios Clínicos como Assunto
Legislação Médica/tendências
[Mh] Termos MeSH secundário: Bases de Dados Factuais
Seres Humanos
Projetos de Pesquisa
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170425
[Lr] Data última revisão:
170425
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170210
[St] Status:MEDLINE
[do] DOI:10.1002/cpt.652



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