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  1 / 238113 MEDLINE  
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[PMID]:29446578
[Au] Autor:Pogorelova IG; Amgalan G
[Ti] Título:[Characteristics of physical growth of schoolchildren in Mongolia and their forming factors].
[So] Source:Gig Sanit;95(12):1198-201, 2016.
[Is] ISSN:0016-9900
[Cp] País de publicação:Russia (Federation)
[La] Idioma:rus
[Ab] Resumo:The article considers the findings of hygienic assessments of educational conditions in urban and rural schools in Mongolia and socio-economic conditions of living of schoolchildren and analysis of anthropometric measurements of schoolchildren aged of 7-16 years in relation to the assessment of harmonicity of their physical development. Hygienic conditions in Mongolian schools are characterized by improper organization of the educational - accomplishment process, high occupancy rate in classes causing insufficient space for a pupil and disconformity of school furniture parameters of school desks and chairs to growth and age requirements of pupils. Comparative assessment of socio-economic factors revealed (выделено автором) that the majority (84.1%) of rural pupils reside in uncomfortable houses and gerdwellings, 58.5 % - in large families with many children, 46.3 % - in families with poor living conditions. There were obtained data about differences in physical development of urban and rural schoolchildren pronounced with age by the gain in the number of children with disharmonious development and children with lower physical indices of the development, delayed by 1-2 years appearance of the crossing of growth and growth shift typical for rural children in comparison with their urban counterparts. According to results of multivariate regression analysis most significant factors for the formation of physical development of school children in descending order are academic workload, the place of residence, the number of children in the family, uncomfortable living conditions, household income and parent's education. In the presence of these factors, the risk of the formation of disharmonious physical growth of school children increases by 1.8-2.8 times. The probability of the risk offormation of disharmonious physical development of schoolchildren living in rural areas was found to be by 2.5 times more than for their urban counterparts. The results can be usedfor scientific substantiation and development of targeted health measures.
[Mh] Termos MeSH primário: Desenvolvimento do Adolescente
Desenvolvimento Infantil
[Mh] Termos MeSH secundário: Adolescente
Antropometria/métodos
Criança
Monitoramento Ambiental/métodos
Monitoramento Ambiental/estatística & dados numéricos
Feminino
Disparidades nos Níveis de Saúde
Seres Humanos
Masculino
Mongólia/epidemiologia
População Rural
Serviços de Saúde Escolar/estatística & dados numéricos
Fatores Sexuais
Fatores Socioeconômicos
População Urbana
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180309
[Lr] Data última revisão:
180309
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180216
[St] Status:MEDLINE


  2 / 238113 MEDLINE  
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[PMID]:29408531
[Au] Autor:Zhang D; Yang M; Zhou D; Li Z; Cai L; Bao Y; Li H; Shan Z; Liu J; Lv D; Liu Y; Xu C; Ling J; Xu Y; Zhang S; Huang Q; Shi Y; Zhu Y; Lai M
[Ad] Endereço:Department of Pathology, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310058, PR China; Key Laboratory of Disease Proteomics of Zhejiang Province, Hangzhou, Zhejiang 310058, PR China.
[Ti] Título:The polymorphism rs671 at ALDH2 associated with serum uric acid levels in Chinese Han males: A genome-wide association study.
[So] Source:Gene;651:62-69, 2018 Apr 20.
[Is] ISSN:1879-0038
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Serum uric acid (SUA) levels are highly heritable and an increased SUA level is one of important risk factors for gout, diabetes, metabolic syndrome, and cardiovascular diseases. The genetic variants underlying SUA remains largely unexplored. The aim was to explore new genetic variants underlying SUA in Chinese Han. We performed a genome-wide association study of SUA levels in Han Chinese. The discovery set contained 1634 samples and subsequent replication was comprised of 1649 females and 1169 males. 2620 subjects were recruited in the detailed analysis of rs671, alcohol drinking and SUA. We found a genome-wide significant association between SUA level and the SNP rs671 at ALDH2 (P = 1.2 × 10 ) in the merged data. In addition, we also replicated the signal from rs3733590 at SLC2A9 (P = 1.0 × 10 ). In males, about 0.21% to 1.95% of the total variance for SUA can be explained by rs671 using linear regression models in four independent cohorts. Of those, 56.75% to 93.51% might be explained by altering alcohol consumption due to rs671. No statistical association of rs671 and SUA was observed in females (P = 0.409). Furthermore, we observed a causal relationship between alcohol consumption and SUA in males using rs671 as an instrumental variable (P = 5.1 × 10 ). We replicated the previous findings in SLC2A9. Our evidence supported that rs671 was associated with SUA by affecting alcohol consumption in males. This finding strongly suggests a role for alcohol consumption in the development of hyperuricaemia and uric acid related traits.
[Mh] Termos MeSH primário: Aldeído-Desidrogenase Mitocondrial/genética
Grupo com Ancestrais do Continente Asiático/genética
Mutação de Sentido Incorreto
Ácido Úrico/sangue
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Idoso de 80 Anos ou mais
Estudos de Coortes
Feminino
Estudo de Associação Genômica Ampla
Seres Humanos
Masculino
Meia-Idade
Polimorfismo de Nucleotídeo Único
Fatores Sexuais
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
268B43MJ25 (Uric Acid); EC 1.2.1.3 (ALDH2 protein, human); EC 1.2.1.3 (Aldehyde Dehydrogenase, Mitochondrial)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180309
[Lr] Data última revisão:
180309
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180207
[St] Status:MEDLINE


  3 / 238113 MEDLINE  
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[PMID]:29377941
[Au] Autor:Kunio M; Wong G; Markham PM; Edelman ER
[Ad] Endereço:Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America.
[Ti] Título:Sex differences in the outcomes of stent implantation in mini-swine model.
[So] Source:PLoS One;13(1):e0192004, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Sex-related differences have been noted in cardiovascular anatomy, pathophysiology, and treatment responses, yet we continued to drive evaluation of vascular device development in animal models without consideration of animal sex. We aimed to understand sex-related differences in the vascular responses to stent implantation by analyzing the pooled data of endovascular interventions in 164 Yucatan mini-swine (87 female, 77 male). Bare metal stents (BMS) or drug-eluting stents (DES) were implanted in 212 coronary arteries (63 single BMS implantation, 68 single DES implantation, 33 overlapped BMS implantation, and 48 overlapped DES implantation). Histomorphological parameters were evaluated from vascular specimens at 3-365 days after stent implantation and evaluated values were compared between female and male groups. While neointima formation at all times after implantation was invariant to sex, statistically significant differences between female and male groups were observed in injury, inflammation, adventitial fibrosis, and neointimal fibrin deposition. These differences were observed independently, i.e., for different procedure types and at different follow-up timings. Only subtle temporal sex-related differences were observed in extent and timing of resolution of inflammation and fibrin clearance. These subtle sex-related differences may be increasingly important as interventional devices meld novel materials that erode and innovations in drug delivery. Erodible materials may act differently if inflammation has a different temporal sequence with sex, and drug distribution after balloon or stent delivery might be different if the fibrin clearance speaks to different modes of pharmacokinetics in male and female swine.
[Mh] Termos MeSH primário: Modelos Animais
Fatores Sexuais
Stents
[Mh] Termos MeSH secundário: Animais
Feminino
Masculino
Suínos
Porco Miniatura
Túnica Íntima
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180309
[Lr] Data última revisão:
180309
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180130
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0192004


  4 / 238113 MEDLINE  
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[PMID]:28467207
[Au] Autor:Moon S
[Ad] Endereço:a Department of Nursing , College of Medicine, University of Ulsan , Ulsan , South Korea.
[Ti] Título:Unhealthy Lifestyle Behaviors in Korean People with Metabolic Syndrome.
[So] Source:J Community Health Nurs;34(2):69-79, 2017 Apr-Jun.
[Is] ISSN:1532-7655
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:This study identified factors associated with unhealthy lifestyle behaviors in people with metabolic syndrome in South Korea. The sample consisted of 1,207 subjects with metabolic syndrome from the Sixth Korea National Health and Nutrition Examination Survey conducted in 2014. High-risk alcohol consumption, smoking, aerobic physical activity, leisure physical activity, excessive carbohydrate intake, and fat intake were measured. A secondary data analysis was performed using chi-square tests and logistic regression. Gender was associated with all unhealthy behaviors. The number of metabolic syndrome components, a poor perceived health status, and attempts to control weight were associated with physical inactivity. Those findings may be helpful to develop a tailored lifestyle modification programs for people with metabolic syndrome.
[Mh] Termos MeSH primário: Comportamentos Relacionados com a Saúde
Síndrome Metabólica/psicologia
[Mh] Termos MeSH secundário: Adulto
Idoso
Consumo de Bebidas Alcoólicas/efeitos adversos
Consumo de Bebidas Alcoólicas/epidemiologia
Distribuição de Qui-Quadrado
Estudos Transversais
Carboidratos da Dieta/administração & dosagem
Carboidratos da Dieta/efeitos adversos
Gorduras na Dieta/administração & dosagem
Gorduras na Dieta/efeitos adversos
Exercício
Feminino
Seres Humanos
Estilo de Vida
Modelos Logísticos
Masculino
Meia-Idade
Inquéritos Nutricionais
República da Coreia/epidemiologia
Fatores Sexuais
Fumar/efeitos adversos
Fumar/epidemiologia
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Dietary Carbohydrates); 0 (Dietary Fats)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180309
[Lr] Data última revisão:
180309
[Sb] Subgrupo de revista:IM; N
[Da] Data de entrada para processamento:170504
[St] Status:MEDLINE
[do] DOI:10.1080/07370016.2017.1304145


  5 / 238113 MEDLINE  
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[PMID]:28464839
[Au] Autor:Pavlic K; Perme MP
[Ad] Endereço:University of Ljubljana, Faculty of Medicine, Institute for Biostatistics and Medical Informatics, Vrazov trg 2, Ljubljana, 1000, Slovenia.
[Ti] Título:On comparison of net survival curves.
[So] Source:BMC Med Res Methodol;17(1):79, 2017 May 02.
[Is] ISSN:1471-2288
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Relative survival analysis is a subfield of survival analysis where competing risks data are observed, but the causes of death are unknown. A first step in the analysis of such data is usually the estimation of a net survival curve, possibly followed by regression modelling. Recently, a log-rank type test for comparison of net survival curves has been introduced and the goal of this paper is to explore its properties and put this methodological advance into the context of the field. METHODS: We build on the association between the log-rank test and the univariate or stratified Cox model and show the analogy in the relative survival setting. We study the properties of the methods using both the theoretical arguments as well as simulations. We provide an R function to enable practical usage of the log-rank type test. RESULTS: Both the log-rank type test and its model alternatives perform satisfactory under the null, even if the correlation between their p-values is rather low, implying that both approaches cannot be used simultaneously. The stratified version has a higher power in case of non-homogeneous hazards, but also carries a different interpretation. CONCLUSIONS: The log-rank type test and its stratified version can be interpreted in the same way as the results of an analogous semi-parametric additive regression model despite the fact that no direct theoretical link can be established between the test statistics.
[Mh] Termos MeSH primário: Infarto do Miocárdio/mortalidade
[Mh] Termos MeSH secundário: Fatores Etários
Idoso
Simulação por Computador
Interpretação Estatística de Dados
Feminino
Seres Humanos
Masculino
Meia-Idade
Modelos de Riscos Proporcionais
Análise de Regressão
Risco
Fatores Sexuais
Análise de Sobrevida
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180309
[Lr] Data última revisão:
180309
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170504
[St] Status:MEDLINE
[do] DOI:10.1186/s12874-017-0351-3


  6 / 238113 MEDLINE  
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Moimaz, Suzely Adas Saliba
Texto completo SciELO Brasil
[PMID]:29267676
[Au] Autor:Bordin D; Fadel CB; Santos CBD; Garbin CAS; Moimaz SAS; Saliba NA
[Ad] Endereço:Universidade Estadual Paulista "Júlio de Mesquita Filho" - Unesp, Araçatuba School of Dentistry, Department of Pediatric and Social Dentistry, Araçatuba, SP, Brazil.
[Ti] Título:Determinants of oral self-care in the Brazilian adult population: a national cross-sectional study.
[So] Source:Braz Oral Res;31:e115, 2017 Dec 18.
[Is] ISSN:1807-3107
[Cp] País de publicação:Brazil
[La] Idioma:eng
[Ab] Resumo:This study aims to investigate variables related to adherence to oral self-care in the Brazilian adult population. It is an exploratory study, using secondary data from a population-based survey on a representative sample of the adult population of the entire Brazilian territory (n=60202). The sample was selected using a multiple stage approach. The oral self-care indicator was defined by grouping the variables: periodicity of dentist appointments, use of dental floss, toothbrush and toothpaste, frequency of brushing and replacement of the toothbrush. The scores obtained from the indicator were categorized into adequate, partially adequate, and inadequate care. Statistical analysis consisted of dimensionality reduction, and oral self-care-related variables were submitted to logistic regression. The variables mostly related to inadequate or partially adequate oral self-care were: illiteracy (OR = 11.20, OR = 4.81), low educational level (OR = 3.50, OR = 1.96), negative oral health self-concept (OR=3.73, OR=1.74), absence of natural teeth (OR = 4.98, OR=2.60), edentulous lower arch (OR = 3.09; _____), number of missing upper teeth (OR=1.14, OR=1.05), absence of health insurance (OR=2.23, OR=2.07), sedentary lifestyle (OR=2.77, OR=1.51), and smoking (OR=2.18, OR=1.40). It was concluded that the individual's level of education is one of the main factors for adherence to adequate oral self-care, followed by level of oral health self-concept and tooth loss. Likewise, lifestyle also bears a significant influence.
[Mh] Termos MeSH primário: Inquéritos de Saúde Bucal/estatística & dados numéricos
Saúde Bucal/estatística & dados numéricos
Cooperação do Paciente/estatística & dados numéricos
Autocuidado/estatística & dados numéricos
[Mh] Termos MeSH secundário: Adolescente
Adulto
Fatores Etários
Brasil
Estudos Transversais
Feminino
Conhecimentos, Atitudes e Prática em Saúde
Seres Humanos
Masculino
Meia-Idade
Fatores Sexuais
Fatores Socioeconômicos
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:D; IM
[Da] Data de entrada para processamento:171222
[St] Status:MEDLINE


  7 / 238113 MEDLINE  
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Texto completo SciELO Brasil
[PMID]:29267666
[Au] Autor:Iriya PMO; Romaniszen LW; Fernandes TMF; Poleti ML
[Ad] Endereço:Universidade Estadual do Norte do Paraná - Unopar, Londrina, PR, Brazil.
[Ti] Título:Health-related quality of life of patients with squamous cell carcinoma: a comparison according to tumor location.
[So] Source:Braz Oral Res;31:e105, 2017 Dec 18.
[Is] ISSN:1807-3107
[Cp] País de publicação:Brazil
[La] Idioma:eng
[Ab] Resumo:The aim of this study was to evaluate the health-related quality of life (QOL) of patients with squamous cell carcinoma (SCC) according to tumor location. The sample consisted of 27 patients with primary SCC in the oral cavity (n = 15), pharynx (n = 7), and larynx (n = 5) who were undergoing cancer treatment at the Cancer Hospital of Londrina, regardless of age, sex, clinical stage, and type of antineoplastic treatment. Health-related QOL was evaluated using the 30-item Cancer-Quality of Life Questionnaire (QLQ-C30), the 35-item Head and Neck Cancer-Quality of Life Questionnaire (QLQ-HN35), and the University of Washington Quality of Life Questionnaire (UW-QOL). These questionnaires were administered individually to each patient before ambulatory care. Sociodemographic data (age and sex) and clinical data (T stage, tumor location, and type of antineoplastic treatment) were collected from the patients' medical records. Scores were compared according to tumor location using the chi-squared test and one-way analysis of variance (p < 0.05). No score differed significantly according to tumor location. It can be concluded that the health-related QOL of patients with SCC was not influenced by tumor location.
[Mh] Termos MeSH primário: Carcinoma de Células Escamosas
Neoplasias Laríngeas
Neoplasias Bucais
Neoplasias Faríngeas
Qualidade de Vida
[Mh] Termos MeSH secundário: Fatores Etários
Idoso
Análise de Variância
Antineoplásicos/uso terapêutico
Carcinoma de Células Escamosas/tratamento farmacológico
Carcinoma de Células Escamosas/patologia
Estudos Transversais
Feminino
Seres Humanos
Neoplasias Laríngeas/tratamento farmacológico
Neoplasias Laríngeas/patologia
Masculino
Meia-Idade
Neoplasias Bucais/tratamento farmacológico
Neoplasias Bucais/patologia
Estadiamento de Neoplasias
Neoplasias Faríngeas/tratamento farmacológico
Neoplasias Faríngeas/patologia
Fatores Sexuais
Inquéritos e Questionários
[Pt] Tipo de publicação:JOURNAL ARTICLE; OBSERVATIONAL STUDY
[Nm] Nome de substância:
0 (Antineoplastic Agents)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:D; IM
[Da] Data de entrada para processamento:171222
[St] Status:MEDLINE


  8 / 238113 MEDLINE  
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[PMID]:29265788
[Au] Autor:Jezewska-Zychowicz M; Guzek D
[Ad] Endereço:Warsaw University of Life Sciences, Faculty of Human Nutrition and Consumer Sciences, Department of Organization and Consumption Economics, Warsaw, Poland
[Ti] Título:Associations between adult perception of body weight, diet, preparing meals and dietary patterns
[So] Source:Rocz Panstw Zakl Hig;68(4):381-387, 2017.
[Is] ISSN:0035-7715
[Cp] País de publicação:Poland
[La] Idioma:eng
[Ab] Resumo:Background: The links between dietary patterns, the perception of one's body weight and diet as well preparing meals are poorly recognised in the literature. In order to develop effective nutritional education and focused interventions, more of such information is thereby required to improve the nation's health Objective: To identify dietary patterns based on declared food consumption rates and subject responses on whether dieting, perception of body weight and diet and preparing meals are linked to such dietary patterns Material and methods: The survey was conducted in 2016 on 344 consumers chosen for age (20-65 years) and their consent for study participation. Rates of eating the foods selected were measured using a 7-point scale. Cluster analysis was used to identify three dietary patterns of behaviour: 'potentially beneficial to health', 'potentially unfavourable for health; deficient' and 'potentially unfavourable for health; excessive'. The analysis was performed using IBM SPSS Statistics version 23.0 Results: There were significantly more subjects showing 'potentially beneficial for health' behaviour, normal body weight, those dieting (whether now or in the past) and those who evaluated their diet as being very good or good compared to other groups. They were also more involved in preparing their meals at home. Differences were found between the 'unfavourable for health' dietary patterns concerning subject's involvement in meal preparation. The dietary pattern for 'deficient' behaviour found lower rates of those preparing their meals at home Conclusions: The pattern of potentially beneficial dietary habits was linked to weight control through a slimming diet and greater involvement in the preparation of food for consumption. The results show the need to develop food choice skills rather than just transferring knowledge in the nutrition education process
[Mh] Termos MeSH primário: Dieta/psicologia
Comportamento Alimentar/psicologia
Preferências Alimentares/psicologia
Conhecimentos, Atitudes e Prática em Saúde
Peso Corporal Ideal
Refeições/psicologia
[Mh] Termos MeSH secundário: Adulto
Índice de Massa Corporal
Análise por Conglomerados
Ingestão de Alimentos/psicologia
Feminino
Seres Humanos
Masculino
Meia-Idade
Percepção
Fatores Sexuais
Inquéritos e Questionários
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171222
[St] Status:MEDLINE


  9 / 238113 MEDLINE  
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[PMID]:29265781
[Au] Autor:Czekajlo A; Rózanska D; Mandecka A; Konikowska K; Madalinska M; Regulska-Ilow B
[Ad] Endereço:Wroclaw Medical University, Faculty of Health Sciences, Department of Dietetics, Wroclaw, Poland
[Ti] Título:Comparison of nutritional value of "fruit and vegetables" and "western" dietary patterns identified in a group of cancer patients
[So] Source:Rocz Panstw Zakl Hig;68(4):365-373, 2017.
[Is] ISSN:0035-7715
[Cp] País de publicação:Poland
[La] Idioma:eng
[Ab] Resumo:Background: Dietary patterns (DPs) are defined as the amounts, types and combinations of various food products in habitual diets and the frequency of their consumption. Dietary pattern analysis is usually performed in order to assess the combined effect of consumed food products on health Objective: The aim of the study was to assess and compare the nutritional value of dietary patterns identified in a group of patients staying on the oncological ward Material and methods: The study group consisted of 100 patients (51 women and 49 men) aged 19-83 years. Dietary intake was assessed using a food frequency questionnaire (FFQ) validated for the population of Lower Silesian Voivodeship Results: Factor analysis identified two main dietary patterns explaining 25.6% of variance. The "fruit and vegetables" DP consisted of vegetables, fruits, juices, unrefined grains and nuts, seeds and raisins. Instead, the "Western" DP was characterized by the consumption of high-fat and processed meat and poultry, fried fish, refined grains, honey and sugar, fats, sweets, beverages and chips. While higher scores for "fruit and vegetables" pattern were associated with increased intake of dietary fiber, antioxidant vitamins, folic acid and decreased glycemic load per 1000 kcal and sodium intake, for "Western" pattern observed relationships were opposite. Women were more likely to have higher factor scores for "fruit and vegetables" DP and lower factor scores for "Western" DP than men Conclusions: Dietary patterns identified in the study group differed in terms of nutritional value, in spite of similar macronutrient content in the diet. "Western" DP was characterized by lower nutritional value than "fruit and vegetables" dietary pattern.
[Mh] Termos MeSH primário: Dieta Ocidental
Comportamento Alimentar
Frutas
Neoplasias/terapia
Valor Nutritivo
Verduras
[Mh] Termos MeSH secundário: Adulto
Idoso
Idoso de 80 Anos ou mais
Ingestão de Energia
Análise Fatorial
Feminino
Seres Humanos
Masculino
Meia-Idade
Avaliação Nutricional
Polônia
Fatores Sexuais
Inquéritos e Questionários
Adulto Jovem
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171222
[St] Status:MEDLINE


  10 / 238113 MEDLINE  
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[PMID]:29209154
[Au] Autor:Tinsley GM; Hamm MA; Hurtado AK; Cross AG; Pineda JG; Martin AY; Uribe VA; Palmer TB
[Ad] Endereço:Energy Balance & Body Composition Laboratory, Musculoskeletal Assessment Laboratory, Department of Kinesiology & Sport Management, Texas Tech University, Box 43011, Lubbock, TX 79409 USA.
[Ti] Título:Effects of two pre-workout supplements on concentric and eccentric force production during lower body resistance exercise in males and females: a counterbalanced, double-blind, placebo-controlled trial.
[So] Source:J Int Soc Sports Nutr;14:46, 2017.
[Is] ISSN:1550-2783
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Background: Pre-workout supplements purportedly enhance feelings of energy, reduce fatigue and improve exercise performance. The purpose of this study was to examine the performance effects of caffeinated and non-caffeinated multi-ingredient pre-workout supplements. Methods: In a counterbalanced, double-blind, placebo-controlled design, eccentric and concentric force production during lower body resistance exercise on a mechanized squat device were assessed after supplement ingestion. Repetitions-in-reserve/RPE and subjective feelings of energy, focus and fatigue were also examined. Twenty-one resistance-trained adults (12 F, 9 M) completed three conditions in random order: caffeinated supplement, non-caffeinated supplement and placebo. Subjects were not informed of the presence of a placebo condition. Thirty minutes after supplement ingestion, a 3-repetition maximum test and 5 sets of 6 repetitions were completed using the squat device. Each repetition involved 4-s eccentric and concentric phases, and the force signal throughout each repetition was sampled from a load cell contained within the squat device. The scaled and filtered force signals were analyzed using customized software. Repeated measures analysis of variance and appropriate follow-up analyses were utilized to compare dependent variables, and relevant effect sizes (d) were calculated. Results: Supplement or placebo ingestion led to similar subjective responses ( > 0.05). Energy (+8 to 44%; d = 0.3 to 0.8) and focus (+8 to 25%; d = 0.3 to 0.5) were acutely increased by supplement or placebo ingestion and decreased as the exercise session progressed. Fatigue was acutely decreased by supplement or placebo ingestion (-7 to 38%; d = -0.1 to -0.6) and increased as the exercise session progressed. Eccentric and concentric forces were unimproved by supplementation during the exercise sets for both sexes. In the non-caffeinated supplement condition only, maximal eccentric force production was lower during sets 3 to 5, as compared to set 1 ( < 0.05). Effect size data indicated that both the caffeinated and non-caffeinated supplements may contribute to small increases in concentric force production in males (+5 to 20%, d = 0.2 to 0.4 relative to placebo), but not females. Conclusions: As compared to placebo, caffeinated and non-caffeinated multi-ingredient pre-workout supplements failed to improve concentric and eccentric force production. In males, effect size data indicate a possible small benefit of supplementation on concentric force production, although this was not statistically significant. When resistance-trained subjects were unaware of the presence of a placebo, resistance exercise performance was similar regardless of whether a placebo or multi-ingredient supplement was ingested.
[Mh] Termos MeSH primário: Cafeína/farmacologia
Suplementos Nutricionais
Músculo Esquelético/efeitos dos fármacos
Músculo Esquelético/fisiologia
Treinamento de Resistência
[Mh] Termos MeSH secundário: Análise de Variância
Método Duplo-Cego
Fadiga
Feminino
Alimentos Formulados
Seres Humanos
Masculino
Resistência Física/efeitos dos fármacos
Resistência Física/fisiologia
Fatores Sexuais
Fenômenos Fisiológicos da Nutrição Esportiva
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
3G6A5W338E (Caffeine)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171207
[St] Status:MEDLINE
[do] DOI:10.1186/s12970-017-0203-x



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