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[PMID]:28818143
[Au] Autor:Fomina E; Savinkina A
[Ti] Título:Locomotion Strategy and Magnitude of Ground Reaction Forces During Treadmill Training on ISS.
[So] Source:Aerosp Med Hum Perform;88(9):841-849, 2017 Sep 01.
[Is] ISSN:2375-6314
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: Creation of the cosmonaut in-flight physical training process is currently based on the leading role of support afferents in the development of hypogravity changes in the motor system. We assume that the strength of support afferents is related to the magnitude of the ground reaction forces (GRF). For this purpose it was necessary to compare the GRF magnitude on the Russian BD-2 treadmill for different locomotion types (walking and running), modes (active and passive), and subjects. METHODS: Relative GRF values were analyzed while subjects performed walking and running during active and passive modes of treadmill belt movement under 1 G (N = 6) and 0 G (N = 4) conditions. RESULTS: For different BD-2 modes and both types of locomotion, maximum GRF values varied in both 0 G and 1 G. Considerable individual variations were also found in the locomotion strategies, as well as in maximum GRF values. In 0 G, the smallest GRF values were observed for walking in active mode, and the largest during running in passive mode. In 1 G, GRF values were higher during running than while walking, but the difference between active and passive modes was not observed; we assume this was due to the uniqueness of the GRF profile. DISCUSSION: The maximum GRF recorded during walking and running in active and passive modes depended on the individual pattern of locomotion. The maximum GRF values that we recorded on BD-2 were close to values found by other researchers. The observations from this study could guide individualized countermeasures prescriptions for microgravity.Fomina E, Savinkina A. Locomotion strategy and magnitude of ground reaction forces during treadmill training on ISS. Aerosp Med Hum Perform. 2017; 88(9):841-849.
[Mh] Termos MeSH primário: Hipogravidade
Locomoção/fisiologia
Educação Física e Treinamento
[Mh] Termos MeSH secundário: Adulto
Medicina Aeroespacial
Fenômenos Biomecânicos
Seres Humanos
Masculino
Federação Russa
Simulação de Ambiente Espacial
Suporte de Carga
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171010
[Lr] Data última revisão:
171010
[Sb] Subgrupo de revista:IM; S
[Da] Data de entrada para processamento:170819
[St] Status:MEDLINE
[do] DOI:10.3357/AMHP.4695.2017


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[PMID]:28767703
[Au] Autor:Krause AR; Speacht TL; Zhang Y; Lang CH; Donahue HJ
[Ad] Endereço:Department of Orthopaedics, Penn State College of Medicine, Hershey, Pennsylvania, United States of America.
[Ti] Título:Simulated space radiation sensitizes bone but not muscle to the catabolic effects of mechanical unloading.
[So] Source:PLoS One;12(8):e0182403, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Deep space travel exposes astronauts to extended periods of space radiation and mechanical unloading, both of which may induce significant muscle and bone loss. Astronauts are exposed to space radiation from solar particle events (SPE) and background radiation referred to as galactic cosmic radiation (GCR). To explore interactions between skeletal muscle and bone under these conditions, we hypothesized that decreased mechanical load, as in the microgravity of space, would lead to increased susceptibility to space radiation-induced bone and muscle loss. We evaluated changes in bone and muscle of mice exposed to hind limb suspension (HLS) unloading alone or in addition to proton and high (H) atomic number (Z) and energy (E) (HZE) (16O) radiation. Adult male C57Bl/6J mice were randomly assigned to six groups: No radiation ± HLS, 50 cGy proton radiation ± HLS, and 50 cGy proton radiation + 10 cGy 16O radiation ± HLS. Radiation alone did not induce bone or muscle loss, whereas HLS alone resulted in both bone and muscle loss. Absolute trabecular and cortical bone volume fraction (BV/TV) was decreased 24% and 6% in HLS-no radiation vs the normally loaded no-radiation group. Trabecular thickness and mineral density also decreased with HLS. For some outcomes, such as BV/TV, trabecular number and tissue mineral density, additional bone loss was observed in the HLS+proton+HZE radiation group compared to HLS alone. In contrast, whereas HLS alone decreased muscle mass (19% gastrocnemius, 35% quadriceps), protein synthesis, and increased proteasome activity, radiation did not exacerbate these catabolic outcomes. Our results suggest that combining simulated space radiation with HLS results in additional bone loss that may not be experienced by muscle.
[Mh] Termos MeSH primário: Osso Esponjoso/efeitos da radiação
Osso Cortical/efeitos da radiação
Elevação dos Membros Posteriores/métodos
Músculo Esquelético/efeitos da radiação
[Mh] Termos MeSH secundário: Animais
Osso Esponjoso/diagnóstico por imagem
Osso Cortical/diagnóstico por imagem
Radiação Cósmica
Masculino
Camundongos
Músculo Esquelético/diagnóstico por imagem
Distribuição Aleatória
Atividade Solar
Simulação de Ambiente Espacial
Microtomografia por Raio-X
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170929
[Lr] Data última revisão:
170929
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170803
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0182403


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[PMID]:28759391
[Au] Autor:Loo S; Campbell A; Vyas J; Pillarisetti N
[Ad] Endereço:Pediatric Respiratory Department, Starship Children's Hospital, Auckland, New Zealand; and.
[Ti] Título:Case Report of a Hypobaric Chamber Fitness to Fly Test in a Child With Severe Cystic Lung Disease.
[So] Source:Pediatrics;140(1), 2017 Jul.
[Is] ISSN:1098-4275
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Patients with severe cystic lung disease are considered to be at risk for cyst rupture during air travel because of the possibility of increase in cyst size and impaired equilibration of pressure between the cysts and other parts of the lung. This may have clinically devastating consequences for the patient but may also result in significant costs for emergency alteration of flight schedule. We report the use of a hypobaric chamber to simulate cabin pressure changes encountered on a commercial flight to assess the safety to fly of a child with severe cystic lung disease secondary to Langerhans cell histiocytosis. The test did not result in an air leak, and the child subsequently undertook air travel without mishap. This is the first reported use of a hypobaric chamber test in a child with severe cystic lung disease. This test has the potential to be used as a fitness to fly test in children at risk for air leak syndromes who are being considered for air travel.
[Mh] Termos MeSH primário: Medicina Aeroespacial/métodos
Histiocitose de Células de Langerhans/complicações
Pneumopatias/complicações
Simulação de Ambiente Espacial/métodos
[Mh] Termos MeSH secundário: Aeronaves
Criança
Cistos
Seres Humanos
Hipóxia
Pneumopatias/diagnóstico
Masculino
Fatores de Risco
Tomografia Computadorizada por Raios X
Viagem
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170907
[Lr] Data última revisão:
170907
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170801
[St] Status:MEDLINE


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[PMID]:28720191
[Au] Autor:Suresh R; Blue RS; Mathers C; Castleberry TL; Vanderploeg JM
[Ti] Título:Sustained Accelerated Idioventricular Rhythm in a Centrifuge-Simulated Suborbital Spaceflight.
[So] Source:Aerosp Med Hum Perform;88(8):789-793, 2017 Aug 01.
[Is] ISSN:2375-6314
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: Hypergravitational exposures during human centrifugation are known to provoke dysrhythmias, including sinus dysrhythmias/tachycardias, premature atrial/ventricular contractions, and even atrial fibrillations or flutter patterns. However, events are generally short-lived and resolve rapidly after cessation of acceleration. This case report describes a prolonged ectopic ventricular rhythm in response to high G exposure. CASE REPORT: A previously healthy 30-yr-old man voluntarily participated in centrifuge trials as a part of a larger study, experiencing a total of 7 centrifuge runs over 48 h. Day 1 consisted of two +Gz runs (peak +3.5 Gz, run 2) and two +Gx runs (peak +6.0 Gx, run 4). Day 2 consisted of three runs approximating suborbital spaceflight profiles (combined +Gx and +Gz). Hemodynamic data collected included blood pressure, heart rate, and continuous three-lead electrocardiogram. Following the final acceleration exposure of the last Day 2 run (peak +4.5 Gx and +4.0 Gz combined, resultant +6.0 G), during a period of idle resting centrifuge activity (resultant vector +1.4 G), the subject demonstrated a marked change in his three-lead electrocardiogram from normal sinus rhythm to a wide-complex ectopic ventricular rhythm at a rate of 91-95 bpm, consistent with an accelerated idioventricular rhythm (AIVR). This rhythm was sustained for 2 m, 24 s before reversion to normal sinus. The subject reported no adverse symptoms during this time. DISCUSSION: While prolonged, the dysrhythmia was asymptomatic and self-limited. AIVR is likely a physiological response to acceleration and can be managed conservatively. Vigilance is needed to ensure that AIVR is correctly distinguished from other, malignant rhythms to avoid inappropriate treatment and negative operational impacts.Suresh R, Blue RS, Mathers C, Castleberry TL, Vanderploeg JM. Sustained accelerated idioventricular rhythm in a centrifuge-simulated suborbital spaceflight. Aerosp Med Hum Perform. 2017; 88(8):789-793.
[Mh] Termos MeSH primário: Ritmo Idioventricular Acelerado/etiologia
Hipergravidade/efeitos adversos
Simulação de Ambiente Espacial
[Mh] Termos MeSH secundário: Ritmo Idioventricular Acelerado/fisiopatologia
Adulto
Medicina Aeroespacial
Doenças Assintomáticas
Centrifugação
Eletrocardiografia
Seres Humanos
Masculino
Remissão Espontânea
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170926
[Lr] Data última revisão:
170926
[Sb] Subgrupo de revista:IM; S
[Da] Data de entrada para processamento:170720
[St] Status:MEDLINE
[do] DOI:10.3357/AMHP.4896.2017


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[PMID]:28720190
[Au] Autor:Reyes DP; Brinley AA; Blue RS; Gruschkus SK; Allen AT; Parazynski SE
[Ti] Título:Clinical Herpes Zoster in Antarctica as a Model for Spaceflight.
[So] Source:Aerosp Med Hum Perform;88(8):784-788, 2017 Aug 01.
[Is] ISSN:2375-6314
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: Antarctica is a useful analog for spaceflight, as both environments are remote, isolated, and with limited resources. While previous studies have demonstrated increased asymptomatic viral shedding in both the Antarctic and spaceflight environments, clinical manifestations of reactivated viral disease have been less frequently identified. We sought to identify the incidence of clinical herpes zoster from viral reactivation in the Antarctic winter-over population. METHODS: Medical records from the 2014 winter season were reviewed for the incidence of zoster in U.S. Antarctic personnel and then compared to the age-matched U.S. RESULTS: Five cases of clinical herpes zoster occurred in the Antarctic Station population of 204 persons, for an incidence of 33.3 per 1000 person-years vs. 3.2 per 1000 person-years in the general population. Four cases were in persons under age 40, yielding an incidence of 106.7 per 1000 person-years in persons ages 30-39 compared to an incidence of 2.0 per 1000 person-years in the same U.S. age group. DISCUSSION: Immune suppression due to the stressful Antarctic environment may have contributed to the increased incidence of herpes zoster in U.S. Antarctic personnel during the winter of 2014. Working and living in isolated, confined, and extreme environments can cause immune suppression, reactivating latent viruses and increasing viral shedding and symptomatic disease. Such changes have been observed in other austere environments, including spaceflight, suggesting that clinical manifestations of viral reactivation may be seen in future spaceflight.Reyes DP, Brinley AA, Blue RS, Gruschkus SK, Allen AT, Parazynski SE. Clinical herpes zoster in Antarctica as a model for spaceflight. Aerosp Med Hum Perform. 2017; 88(8):784-788.
[Mh] Termos MeSH primário: Herpes Zoster/epidemiologia
Simulação de Ambiente Espacial
[Mh] Termos MeSH secundário: Adulto
Idoso
Regiões Antárticas/epidemiologia
Feminino
Herpes Zoster/imunologia
Seres Humanos
Hospedeiro Imunocomprometido/imunologia
Incidência
Masculino
Meia-Idade
Estações do Ano
Voo Espacial
Estresse Fisiológico/imunologia
Estresse Psicológico/imunologia
Estados Unidos/epidemiologia
Eliminação de Partículas Virais
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170926
[Lr] Data última revisão:
170926
[Sb] Subgrupo de revista:IM; S
[Da] Data de entrada para processamento:170720
[St] Status:MEDLINE
[do] DOI:10.3357/AMHP.4450.2017


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[PMID]:28720184
[Au] Autor:Cao S; Zhang Y; Guo Y; Chen S
[Ti] Título:Human Performance Time Model of Spacecraft Control Panel Operation in Simulated Microgravity.
[So] Source:Aerosp Med Hum Perform;88(8):743-751, 2017 Aug 01.
[Is] ISSN:2375-6314
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Human performance modeling plays an important role in the design and management of human spaceflight missions. Previous studies reported that manual control task time increased in microgravity conditions. The current study aimed to find a modeling method that can quantify and predict the task time of spacecraft control panel operation in the simulated microgravity condition. METHODS: We proposed the application of a predetermined elemental task method together with an information processing time model to quantify both physical motion time and cognitive time. The time increment due to microgravity was hypothesized to be proportional to physical motion time. The total task time in the microgravity condition could be calculated as the model time from the normal ground condition plus the predicted time increment. Human data were collected from an experiment asking participants to perform six emergency operating procedure tasks in both normal ground and simulated microgravity conditions. RESULTS: The proposed method resulted in good fitness to human data in both conditions, as shown by both regression fitness (R2 values = 0.99) and modeling error measures (root mean square error ≤ 3.3 s; mean absolute percentage error ≤ 16.1%). CONCLUSIONS: Although the method has its limitations, the current findings suggest that it has value in aerospace human factors and ergonomics applications.Cao S, Zhang Y, Guo Y, Chen S. Human performance time model of spacecraft control panel operation in simulated microgravity. Aerosp Med Hum Perform. 2017; 88(8):743-751.
[Mh] Termos MeSH primário: Emergências
Simulação de Ambiente Espacial
Astronave
Análise e Desempenho de Tarefas
Simulação de Ausência de Peso
[Mh] Termos MeSH secundário: Adulto
Medicina Aeroespacial
Seres Humanos
Masculino
Fatores de Tempo
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170926
[Lr] Data última revisão:
170926
[Sb] Subgrupo de revista:IM; S
[Da] Data de entrada para processamento:170720
[St] Status:MEDLINE
[do] DOI:10.3357/AMHP.4668.2017


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[PMID]:28720182
[Au] Autor:Cavanagh P; Rice A; Glauberman M; Sudduth A; Cherones A; Davis S; Lewis M; Hanson A; Wilt G
[Ti] Título:Ground Reaction Forces During Reduced Gravity Running in Parabolic Flight.
[So] Source:Aerosp Med Hum Perform;88(8):730-736, 2017 Aug 01.
[Is] ISSN:2375-6314
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Treadmills have been employed as both a form of exercise and a countermeasure to prevent changes in the musculoskeletal system on almost all NASA missions and many Russian missions since the early Space Shuttle flights. It is possible that treadmills may also be part of exercise programs on future Mars missions and that they may be a component of exercise facilities in lunar or Martian habitats. METHODS: In order to determine if the ambient gravity on these destinations will provide osteogenic effects while performing exercise on a treadmill, ground reactions forces (GRFs) were measured on eight subjects (six women and two men) running at 6 mph during parabolic flight in Martian and lunar gravity conditions. RESULTS: On average, stride length increased as gravity decreased. The first and second peaks of the GRFs decreased by 0.156 and 0.196 bodyweights, respectively, per 1/10 g change in ambient gravity. DISCUSSION: Based on comparisons with previously measured GRF during loaded treadmill running on the International Space Station, we conclude that unloaded treadmill running under lunar and Martian conditions during exploration missions is not likely to be an osteo-protective exercise.Cavanagh P, Rice A, Glauberman M, Sudduth A, Cherones A, Davis S, Lewis M, Hanson A, Wilt G. Ground reaction forces during reduced gravity running in parabolic flight. Aerosp Med Hum Perform. 2017; 88(8):730-736.
[Mh] Termos MeSH primário: Hipogravidade
Corrida/fisiologia
Simulação de Ambiente Espacial
[Mh] Termos MeSH secundário: Medicina Aeroespacial
Fenômenos Biomecânicos
Feminino
Seres Humanos
Masculino
Marte
Lua
Suporte de Carga
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170926
[Lr] Data última revisão:
170926
[Sb] Subgrupo de revista:IM; S
[Da] Data de entrada para processamento:170720
[St] Status:MEDLINE
[do] DOI:10.3357/AMHP.4779.2017


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[PMID]:28683078
[Au] Autor:Turker MS; Grygoryev D; Lasarev M; Ohlrich A; Rwatambuga FA; Johnson S; Dan C; Eckelmann B; Hryciw G; Mao JH; Snijders AM; Gauny S; Kronenberg A
[Ad] Endereço:Oregon Institute of Occupational Health Sciences, Oregon Health & Science University, Portland, Oregon, United States of America.
[Ti] Título:Simulated space radiation-induced mutants in the mouse kidney display widespread genomic change.
[So] Source:PLoS One;12(7):e0180412, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Exposure to a small number of high-energy heavy charged particles (HZE ions), as found in the deep space environment, could significantly affect astronaut health following prolonged periods of space travel if these ions induce mutations and related cancers. In this study, we used an in vivo mutagenesis assay to define the mutagenic effects of accelerated 56Fe ions (1 GeV/amu, 151 keV/µm) in the mouse kidney epithelium exposed to doses ranging from 0.25 to 2.0 Gy. These doses represent fluences ranging from 1 to 8 particle traversals per cell nucleus. The Aprt locus, located on chromosome 8, was used to select induced and spontaneous mutants. To fully define the mutagenic effects, we used multiple endpoints including mutant frequencies, mutation spectrum for chromosome 8, translocations involving chromosome 8, and mutations affecting non-selected chromosomes. The results demonstrate mutagenic effects that often affect multiple chromosomes for all Fe ion doses tested. For comparison with the most abundant sparsely ionizing particle found in space, we also examined the mutagenic effects of high-energy protons (1 GeV, 0.24 keV/µm) at 0.5 and 1.0 Gy. Similar doses of protons were not as mutagenic as Fe ions for many assays, though genomic effects were detected in Aprt mutants at these doses. Considered as a whole, the data demonstrate that Fe ions are highly mutagenic at the low doses and fluences of relevance to human spaceflight, and that cells with considerable genomic mutations are readily induced by these exposures and persist in the kidney epithelium. The level of genomic change produced by low fluence exposure to heavy ions is reminiscent of the extensive rearrangements seen in tumor genomes suggesting a potential initiation step in radiation carcinogenesis.
[Mh] Termos MeSH primário: Cromossomos/efeitos da radiação
Epitélio/efeitos da radiação
Radioisótopos de Ferro/efeitos adversos
Rim/efeitos da radiação
Fótons/efeitos adversos
Translocação Genética/efeitos da radiação
[Mh] Termos MeSH secundário: Animais
Carcinogênese/efeitos da radiação
Cromossomos/química
Radiação Cósmica/efeitos adversos
Feminino
Loci Gênicos/efeitos da radiação
Íons Pesados
Masculino
Camundongos
Camundongos Endogâmicos C57BL
Camundongos Endogâmicos DBA
Simulação de Ambiente Espacial
Técnicas de Cultura de Tecidos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Iron Radioisotopes)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170922
[Lr] Data última revisão:
170922
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170707
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0180412


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[PMID]:28641686
[Au] Autor:Clark TK; Young LR
[Ti] Título:A Case Study of Human Roll Tilt Perception in Hypogravity.
[So] Source:Aerosp Med Hum Perform;88(7):682-687, 2017 Jul 01.
[Is] ISSN:2375-6314
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Increased gravito-inertial acceleration, or hypergravity, such as produced in a centrifuge or in an aircraft coordinated turn, causes humans to systematically overestimate their roll tilt in the dark. This is known as the "G-excess" illusion. We have previously modified a mathematical observer model of dynamic orientation perception to replicate these illusory tilt perceptions. This modified model also made a novel, previously untested, prediction that humans would underestimate acute roll tilt in reduced gravitational environments (hypogravity). CASE REPORT: In the current study, we used aircraft parabolic flight to test this prediction in a single subject. Roll tilt perception was reported using a subjective visual vertical task in which the subject aligned an illuminated line, presented in a head mounted display, with their perceived direction of down. The same subject made reports during hypogravity parabolas (0.165 G and 0.38 G, corresponding to lunar and Martian gravity, respectively), hypergravity maneuvers (1.6 G during a pull out maneuver and 1.2 G during a coordinated turn), and 1-G control conditions (both on the ground and in straight and level flight). As hypothesized, the subject significantly underestimated roll tilt in the hypogravity environments by approximately 40% compared to 1-G reports while overestimating roll tilt in the hypergravity environments. DISCUSSION: The amount of underestimation observed was quantitatively consistent with that predicted a priori by the modified observer model. We propose the term "G-shortage" illusion for the underestimation of roll tilt in hypogravity. This illusion may have implications for aircraft pilots and astronauts.Clark TK, Young LR. A case study of human roll tilt perception in hypogravity. Aerosp Med Hum Perform. 2017; 88(7):682-687.
[Mh] Termos MeSH primário: Hipogravidade
Orientação
Propriocepção
Simulação de Ambiente Espacial
Vestíbulo do Labirinto/fisiopatologia
[Mh] Termos MeSH secundário: Adulto
Voluntários Saudáveis
Seres Humanos
Masculino
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170829
[Lr] Data última revisão:
170829
[Sb] Subgrupo de revista:IM; S
[Da] Data de entrada para processamento:170624
[St] Status:MEDLINE
[do] DOI:10.3357/AMHP.4823.2017


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[PMID]:28641681
[Au] Autor:Blue RS; Bonato F; Seaton K; Bubka A; Vardiman JL; Mathers C; Castleberry TL; Vanderploeg JM
[Ti] Título:The Effects of Training on Anxiety and Task Performance in Simulated Suborbital Spaceflight.
[So] Source:Aerosp Med Hum Perform;88(7):641-650, 2017 Jul 01.
[Is] ISSN:2375-6314
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: In commercial spaceflight, anxiety could become mission-impacting, causing negative experiences or endangering the flight itself. We studied layperson response to four varied-length training programs (ranging from 1 h-2 d of preparation) prior to centrifuge simulation of launch and re-entry acceleration profiles expected during suborbital spaceflight. We examined subject task execution, evaluating performance in high-stress conditions. We sought to identify any trends in demographics, hemodynamics, or similar factors in subjects with the highest anxiety or poorest tolerance of the experience. METHODS: Volunteers participated in one of four centrifuge training programs of varied complexity and duration, culminating in two simulated suborbital spaceflights. At most, subjects underwent seven centrifuge runs over 2 d, including two +Gz runs (peak +3.5 Gz, Run 2) and two +Gx runs (peak +6.0 Gx, Run 4) followed by three runs approximating suborbital spaceflight profiles (combined +Gx and +Gz, peak +6.0 Gx and +4.0 Gz). Two cohorts also received dedicated anxiety-mitigation training. Subjects were evaluated on their performance on various tasks, including a simulated emergency. RESULTS: Participating in 2-7 centrifuge exposures were 148 subjects (105 men, 43 women, age range 19-72 yr, mean 39.4 ± 13.2 yr, body mass index range 17.3-38.1, mean 25.1 ± 3.7). There were 10 subjects who withdrew or limited their G exposure; history of motion sickness was associated with opting out. Shorter length training programs were associated with elevated hemodynamic responses. Single-directional G training did not significantly improve tolerance. DISCUSSION: Training programs appear best when high fidelity and sequential exposures may improve tolerance of physical/psychological flight stressors. The studied variables did not predict anxiety-related responses to these centrifuge profiles.Blue RS, Bonato F, Seaton K, Bubka A, Vardiman JL, Mathers C, Castleberry TL, Vanderploeg JM. The effects of training on anxiety and task performance in simulated suborbital spaceflight. Aerosp Med Hum Perform. 2017; 88(7):641-650.
[Mh] Termos MeSH primário: Ansiedade/psicologia
Voo Espacial
Simulação de Ambiente Espacial/métodos
Análise e Desempenho de Tarefas
[Mh] Termos MeSH secundário: Adulto
Medicina Aeroespacial
Idoso
Centrifugação
Estudos de Coortes
Feminino
Hemodinâmica
Seres Humanos
Masculino
Meia-Idade
Enjoo devido ao Movimento
Estudos Prospectivos
Simulação de Ambiente Espacial/psicologia
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170829
[Lr] Data última revisão:
170829
[Sb] Subgrupo de revista:IM; S
[Da] Data de entrada para processamento:170624
[St] Status:MEDLINE
[do] DOI:10.3357/AMHP.4807.2017



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