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[PMID]: 29505537 [Au] Autor: Chan FK; Hsu CC; Lin HJ; Wang JJ; Su SB; Huang CC; Weng SF [Ad] Endereço: Department of Emergency Medicine, Kuo General Hospital. [Ti] Título: Physicians as well as nonphysician health care professionals in Taiwan have higher risk for lumbar herniated intervertebral disc than general population. [So] Source: Medicine (Baltimore);97(1):e9561, 2018 Jan. [Is] ISSN: 1536-5964 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: Physicians in Taiwan have long working hours and are at risk for inappropriate posture when handling patients, which may contribute to lumbar herniated intervertebral disc (L-HIVD). This study was conducted to delineate this issue, which is still unknown. This nationwide population-based cohort study was based on Taiwan National Health Insurance Research Database. We identified 25,428 physicians, 32,316 nonphysician health care professionals (HCPs), and an identical number of age- and sex-matched individuals from the general population. All individuals who had L-HIVD before 2007 were excluded. We compared the L-HIVD risk between physicians and general population, nonphysician HCPs and general population, and physicians and nonphysician HCPs by tracing their medical histories between 2007 and 2011. A comparison among physician specialties was also performed. Physicians and nonphysician HCPs had higher L-HIVD risk than the general population [odds ratio (OR): 1.149; 95% confidence interval (CI): 1.011-1.307 and OR: 1.220; 95% CI: 1.080-1.378, respectively]. Physicians did not have higher L-HIVD risk than nonphysician HCPs [adjusted OR (AOR): 0.912; 95% CI: 0.795-1.046]. Physician specialties of orthopedics and obstetrics and gynecology had a trend of higher L-HIVD risk than other specialties (AOR: 1.538; 95% CI: 0.805-2.939, and AOR: 1.306; 95% CI: 0.967-1.764, respectively). Physicians as well as nonphysician health care professionals in Taiwan have higher L-HIVD risk than the general population, which could be attributed to a probable role of long working hours. This result provides an important reference for the government to promote occupational health in health care professionals; however, further studies are warranted for the underlying mechanisms. [Mh] Termos MeSH primário: Pessoal Técnico de Saúde/estatística & dados numéricos Deslocamento do Disco Intervertebral/epidemiologia Vértebras Lombares Exposição Ocupacional/efeitos adversos Médicos/estatística & dados numéricos [Mh] Termos MeSH secundário: Adulto Feminino Seres Humanos Deslocamento do Disco Intervertebral/etiologia Masculino Meia-Idade Risco Taiwan/epidemiologia [Pt] Tipo de publicação: JOURNAL ARTICLE; OBSERVATIONAL STUDY [Em] Mês de entrada: 1803 [Cu] Atualização por classe: 180309 [Lr] Data última revisão: 180309 [Sb] Subgrupo de revista: AIM; IM [Da] Data de entrada para processamento: 180306 [St] Status: MEDLINE [do] DOI: 10.1097/MD.0000000000009561

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[PMID]: 29505519 [Au] Autor: Guo ZL; Wang JY; Gong LL; Gan S; Gu CM; Wang SS [Ad] Endereço: The Second Clinical College, Guangzhou University of Chinese Medicine, Guangzhou. [Ti] Título: Association between cadmium exposure and urolithiasis risk: A systematic review and meta-analysis. [So] Source: Medicine (Baltimore);97(1):e9460, 2018 Jan. [Is] ISSN: 1536-5964 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: BACKGROUND: We performed a meta-analysis to determine whether a consistent relationship exists between cadmium exposure and urolithiasis in humans. Accordingly, we summarized and reviewed previously published quantitative studies. METHODS: Eligible studies with reference lists published before June 1, 2017 were obtained from searching several databases. Random effects models were used to summary the overall estimate of the multivariate adjusted odds ratios (ORs) with 95% confidence intervals (CIs). RESULTS: Six observational studies involving 88,045 participants were identified and stratified into the following categories according to cadmium assessment results: occupational (n = 4) and dietary (n = 2). The findings of the meta-analysis suggested that the risk of urolithiasis increases significantly by 1.32 times at higher cadmium exposure (OR = 1.32; 95% CI = 1.08-1.62; for highest vs lowest category urinary cadmium values). The summary OR in occupational exposure (OR = 1.56; 95% CI = 1.13-2.14) increased at the same condition. Meanwhile, no association was observed between cadmium exposure and urolithiasis risk in dietary exposure (OR = 1.13; 95% CI = 0.87-1.47). A significant association remained consistent, as indicated by subgroup analyses and sensitivity analyses. CONCLUSIONS: The meta-analysis indicated that increased risk of urolithiasis is associated with high cadmium exposure, and this association is higher in occupational exposure than in dietary exposure. Nevertheless, well-designed observational studies with different ethnic populations are still needed. [Mh] Termos MeSH primário: Cádmio/toxicidade Exposição Ocupacional/efeitos adversos Urolitíase/induzido quimicamente [Mh] Termos MeSH secundário: Seres Humanos [Pt] Tipo de publicação: JOURNAL ARTICLE; META-ANALYSIS; REVIEW [Nm] Nome de substância: 00BH33GNGH (Cadmium) [Em] Mês de entrada: 1803 [Cu] Atualização por classe: 180309 [Lr] Data última revisão: 180309 [Sb] Subgrupo de revista: AIM; IM [Da] Data de entrada para processamento: 180306 [St] Status: MEDLINE [do] DOI: 10.1097/MD.0000000000009460

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[PMID]: 29446574 [Au] Autor: Rusanova DV; Kuleshova MV; Katamanova EV; Kartapoltseva NV; Pankov VA; Lakhman OL; Kazakova PV; Kuptsova NG [Ti] Título: [Vibration disease: hygienic and medical aspects]. [So] Source: Gig Sanit;95(12):1180-3, 2016. [Is] ISSN: 0016-9900 [Cp] País de publicação: Russia (Federation) [La] Idioma: rus [Ab] Resumo: The hygienic assessment of working conditions of employees exposed to local vibration established that working conditions for employees ofvibration dangerous occupations at the aircraft plant according to the degree from a health standpoint and hazard are referred to the fourth (dangerous) class of the degree of danger that stipulates stable high levels of the morbidity rate. The leading factor is a local vibration that results in the consistently high levels of occupational morbidity rate. There was shown the efficiency of the use of the pulsed magnetic stimulation in the treatment ofpatients with vibration disease associated with the exposure to local vibration. For the evaluation of the effectiveness of treatment in patients the condition of the central nervous system was determined with the use of computer electroencephalography with the registration of visual and auditory evoked potentials and somatosensory evoked potentials; there was studied the state of the peripheral nerves in arms and legs relying upom electromyographic data; there was performed psychological study. After the performance of pulse magnetic stimulation in patients diagnosed to have the vibration diseases there were observed the improvement in the interaction of cortical-subcortical structures and associative areas of the frontal and temporal lobes of the brain. After treatment there was noted the shortening of the time of the conduction of the afferent wave of the excitation at the level of the cervical spinal cord, subcortical structures and the central conduction time. There was restored previously reduced the speed of the conduction of the impulse via the distal parts of the tibial and median nerve, through the ulnar nerve in the area of the elbow joint. There was noted the rise in the average temperature on the hands; the decline of thresholds of vibration and pain sensitivity; the improvement of indices characterizing of the state of mnestic- attentional and psycho-emotional scope of activity. [Mh] Termos MeSH primário: Aeronaves Síndrome da Vibração do Segmento Mão-Braço Estimulação Magnética Transcraniana/métodos Vibração/efeitos adversos [Mh] Termos MeSH secundário: Adulto Excitabilidade Cortical Eletroencefalografia/métodos Síndrome da Vibração do Segmento Mão-Braço/diagnóstico Síndrome da Vibração do Segmento Mão-Braço/etiologia Síndrome da Vibração do Segmento Mão-Braço/terapia Seres Humanos Indústrias/métodos Masculino Meia-Idade Exposição Ocupacional/efeitos adversos Exposição Ocupacional/análise Exposição Ocupacional/prevenção & controle Resultado do Tratamento [Pt] Tipo de publicação: JOURNAL ARTICLE [Em] Mês de entrada: 1803 [Cu] Atualização por classe: 180309 [Lr] Data última revisão: 180309 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 180216 [St] Status: MEDLINE

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[PMID]: 29446573 [Au] Autor: Rukavishnikov VS; Kolycheva IV; Lakhman OL [Ti] Título: [Modern aspects of the conservation and promotion of health of firefighters]. [So] Source: Gig Sanit;95(12):1175-9, 2016. [Is] ISSN: 0016-9900 [Cp] País de publicação: Russia (Federation) [La] Idioma: rus [Ab] Resumo: On the basis of complex hygienic studies there were determined conditions of the work of firefighters in liquidation of foci of fires at the incipient stage, identified the complex of toxic substances, their quantitative content in the area of the smoke of fires. The analysis of the etiological role of occupational factors in the shaping of the morbidity and the physiological and clinical manifestations, established indices of the risk for occupational and industrial-caused pathology have allowed to substantiate the relationship of a number of nosological forms associated with working conditions of firefighters. There was developed a system of preventive activities for the promotion and preservation of the health of firefighters, as well as a conceptual model for monitoring of working conditions and state of health. [Mh] Termos MeSH primário: Bombeiros Doenças Profissionais Serviços Preventivos de Saúde/organização & administração Lesão por Inalação de Fumaça [Mh] Termos MeSH secundário: Adulto Seres Humanos Masculino Doenças Profissionais/etiologia Doenças Profissionais/fisiopatologia Doenças Profissionais/prevenção & controle Exposição Ocupacional/efeitos adversos Exposição Ocupacional/análise Exposição Ocupacional/prevenção & controle Saúde do Trabalhador/normas Medição de Risco Sibéria/epidemiologia Lesão por Inalação de Fumaça/etiologia Lesão por Inalação de Fumaça/fisiopatologia Lesão por Inalação de Fumaça/prevenção & controle [Pt] Tipo de publicação: JOURNAL ARTICLE [Em] Mês de entrada: 1803 [Cu] Atualização por classe: 180309 [Lr] Data última revisão: 180309 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 180216 [St] Status: MEDLINE

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[PMID]: 29446572 [Au] Autor: Pankov VA; Lakhman OL; Perezhogin AN; Tyutkina GA; Kuleshova MV; Smirnova OV [Ti] Título: [The dynamics of the occupational morbidity rate in the Eastern Siberia]. [So] Source: Gig Sanit;95(12):1171-75, 2016. [Is] ISSN: 0016-9900 [Cp] País de publicação: Russia (Federation) [La] Idioma: rus [Ab] Resumo: The dynamics and structure of the occupational morbidity rate in main branches of the industry in the Eastern Siberia for the 2000-2015 (on the example of the Irkutsk region) is presented in this paper. During the observation period there were noted the significant gain in the number of cases of occupational diseases registered in such different branches of industry as Coal and Lignite Mining, ship and aircraft building, and in some other branches (metallurgical production, air transport, pulp production, electric power distribution industry). In the structure of the occupational morbidity leading positions are occupied by diseases associated with the exposure to physical factors, industrial aerosols, physical overload and overexertion of certain organs and systems. The main reasons and factors contributing to the gain of the occupational morbidity rate are the imperfection of technological processes, working places, personal protective equipment and/or their lack, constructive defects of machines and equipment, the violation of safety regulations, regimen of the work and rest, insufficiently high level of medical and preventive maintenance, delayed making of decisions for the rational employment to the workers with the revealed early forms of occupational diseases. There pointed out priority directions of the prevention the implementation of which will allow to decline the level of the occupational morbidity rate. The main directions are the implementation of economically caused mechanisms of the interest in the preservation of workers ' health; implementation of the regional aimed programs; the introduction of new processes, equipment and mechanisms meeting modern hygienic requirements; the assessment of occupational risk with the creation and implementation of the system of monitoring for the dynamics of working conditions and the state of the workers ' health for the making corrective management solutions on the optimization and elevation of the efficacy and relevance of developed and implemented preventive health measures. [Mh] Termos MeSH primário: Indústrias Doenças Profissionais Saúde do Trabalhador/estatística & dados numéricos Saúde Pública [Mh] Termos MeSH secundário: Seres Humanos Indústrias/classificação Indústrias/estatística & dados numéricos Doenças Profissionais/epidemiologia Doenças Profissionais/etiologia Doenças Profissionais/prevenção & controle Exposição Ocupacional/efeitos adversos Exposição Ocupacional/classificação Exposição Ocupacional/prevenção & controle Exposição Ocupacional/estatística & dados numéricos Saúde Pública/métodos Saúde Pública/estatística & dados numéricos Melhoria de Qualidade Sibéria/epidemiologia [Pt] Tipo de publicação: JOURNAL ARTICLE [Em] Mês de entrada: 1803 [Cu] Atualização por classe: 180309 [Lr] Data última revisão: 180309 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 180216 [St] Status: MEDLINE

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[PMID]: 29446298 [Au] Autor: Katamanova EV; Dyakovich MP; Kudaeva IV; Shevchenko OI; Eshchina IM; Rukavishnikov VS; Meshchakova NM [Ti] Título: [Clinical and neurophysiological peculiarities of health disorders in workers in dependence on the vinyl chloride exposure load]. [So] Source: Gig Sanit;95(12):1167-71, 2016. [Is] ISSN: 0016-9900 [Cp] País de publicação: Russia (Federation) [La] Idioma: rus [Ab] Resumo: Results of the clinical and neurophysiological examinations of 42 workers with operating history at the chemical plant exposed to vinyl chloride (VC) are presented. The purpose of research was the identification ofpeculiarities of clinical manifestations and disorders of the functional activity of the brain in workers at the vinyl chloride production, with taking into account the exposure toxic load (ETL). There were made clinical and electroencephalographic examinations with the detection of cognitive evoked potentials (CEP) and statistical analysis of results with the use of the Mann-Whitney U-test, Fisher's F-test, calculation of Spearman's correlation coefficient. The features in clinical picture of the pathology of the nervous system were detected in the form of asthenic disorders with cognitive impairment and autonomic dysfunction syndrome. There was established the increase in the cognitive impairment rate (p = 0.03), the decline in a-EEG activity (p = 0.01) and the worsening of indices of the amplitude (p = 0.011) and latency (p = 0,05) of CEP in extremely high level of ETL in comparison with same indices in the group with moderately high ETL. In the first group there was revealed a statistically significant exceedance of the frequency of hypertension - by 1.6 times, skin diseases - by 9 times, chronic subatrophic rhino-pharyngitis by 1.4 times in comparison with cases from the second group. In the group with moderately high level of ETL there was established the statistically significant inverse correlationship between the ETL and the index of P300 amplitude from the left side (r = -0.38, p = 0.019) and in the group with extremely high level ETL - between ETL and index of the ß2 - rhythm (r = - 0.73, p = 0.0008). [Mh] Termos MeSH primário: Poluentes Ocupacionais do Ar Indústria Manufatureira Síndromes Neurotóxicas Cloreto de Vinil [Mh] Termos MeSH secundário: Poluentes Ocupacionais do Ar/análise Poluentes Ocupacionais do Ar/toxicidade Eletroencefalografia/métodos Seres Humanos Masculino Indústria Manufatureira/métodos Indústria Manufatureira/normas Meia-Idade Síndromes Neurotóxicas/diagnóstico Síndromes Neurotóxicas/epidemiologia Síndromes Neurotóxicas/etiologia Síndromes Neurotóxicas/fisiopatologia Exposição Ocupacional/efeitos adversos Exposição Ocupacional/análise Exposição Ocupacional/prevenção & controle Medição de Risco/métodos Medição de Risco/estatística & dados numéricos Fatores de Risco Sibéria/epidemiologia Fatores de Tempo Cloreto de Vinil/análise Cloreto de Vinil/toxicidade [Pt] Tipo de publicação: JOURNAL ARTICLE [Nm] Nome de substância: 0 (Air Pollutants, Occupational); WD06X94M2D (Vinyl Chloride) [Em] Mês de entrada: 1803 [Cu] Atualização por classe: 180309 [Lr] Data última revisão: 180309 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 180216 [St] Status: MEDLINE

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[PMID]: 29446294 [Au] Autor: Efimova NV; Rukavishnikov VS; Pankov VA; Perezhogin AN; Shayakhmetov SF; Meshchakova NM; Lisetskaya LG [Ti] Título: [Assessment of carcinogenic risks to workers of the main enterprises of the Irkutsk region]. [So] Source: Gig Sanit;95(12):1163-7, 2016. [Is] ISSN: 0016-9900 [Cp] País de publicação: Russia (Federation) [La] Idioma: rus [Ab] Resumo: The purpose of research is the assessment of the individual cancer risk (ICR) for workers of the basic occupations in key branches of industry of the Irkutsk region. There was executed the calculation of ICR levels for workers of the basic occupations of the aircraft industry, aluminum smelters and vinyl chloride production plants. The estimation of the exposure for workers was carried out according to long-term time-weighted average concentrations in the air of the working area, for the population - on annual average concentrations in the ambient air. To assess the risk that is not associated with the profession, the dose was calculated for the period of life (70 years). When calculating the toxicant doses in the working area there were used the "standard" indices ofpulmonary ventilation for adults, body weight, the work experience in the contact with carcinogens of 30 years, the number of days in the contact of 240, the duration of the working time 8 or 12 hours (in accordance with the working hours) duration. ICR for the Irkutsk population amounted of 3.08E-04, in Shelekhov - 4.8E-05, Sayansk - 1.1E-05. The amount of risk depends on the content offormaldehyde in all territories and chromium VI in cities of Irkutsk and Shelekhov. ICR for workers of basic occupations of studied plants in dozens of times are higher than for the urban population. Priority carcinogens are: chromium VI, nickel, formaldehyde, silicon dioxide -for the aircraft plant employees; 1,2-dichloretan, vinyl chloride - for the workers of vinyl chloride production plant; benzopyrene - for the aluminum smelter workers. [Mh] Termos MeSH primário: Poluentes Ocupacionais do Ar Carcinogênese/induzido quimicamente Cromo Formaldeído Indústria Manufatureira Cloreto de Vinil [Mh] Termos MeSH secundário: Poluentes Ocupacionais do Ar/análise Poluentes Ocupacionais do Ar/toxicidade Carcinógenos Ambientais/análise Carcinógenos Ambientais/toxicidade Cromo/análise Cromo/toxicidade Formaldeído/análise Formaldeído/toxicidade Seres Humanos Indústria Manufatureira/métodos Indústria Manufatureira/normas Exposição Ocupacional/efeitos adversos Exposição Ocupacional/análise Exposição Ocupacional/prevenção & controle Medição de Risco/métodos Medição de Risco/estatística & dados numéricos Fatores de Risco Sibéria/epidemiologia Tempo Cloreto de Vinil/análise Cloreto de Vinil/toxicidade [Pt] Tipo de publicação: JOURNAL ARTICLE [Nm] Nome de substância: 0 (Air Pollutants, Occupational); 0 (Carcinogens, Environmental); 0R0008Q3JB (Chromium); 18540-29-9 (chromium hexavalent ion); 1HG84L3525 (Formaldehyde); WD06X94M2D (Vinyl Chloride) [Em] Mês de entrada: 1803 [Cu] Atualização por classe: 180309 [Lr] Data última revisão: 180309 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 180216 [St] Status: MEDLINE

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[PMID]: 29446293 [Au] Autor: Beygel EA; Katamanova EV; Shayakhmetov SF; Ushakova OV; Pavlenko NA; Kuks AN; Voronin DA [Ti] Título: [The impact of the long-term exposure of industrial aerosols on clinical and functional indices of the broncho-pulmonary system in aluminum smelter workers]. [So] Source: Gig Sanit;95(12):1160-3, 2016. [Is] ISSN: 0016-9900 [Cp] País de publicação: Russia (Federation) [La] Idioma: rus [Ab] Resumo: It was found that the appearance of respiratory diseases among workers was established to be associated with the impact of aerosols with the complex chemical composition, exceeding corresponding MAC. Among respiratory diseases in workers there were detected predominantly chronic non-obstructive bronchitis - 59.15%, and chronic obstructive pulmonary disease (COPD) - in 35.2% of cases. In the analysis of spirometric indices of examined patients the vast majority (76.3%) of them showed disturbances of the bronchial patency of mild to moderate degree of the pronouncement. As a result of the implementation offlexible bronchoscopy there was established the presence of a diffuse lesion of bronchi with a predominance of subatrophic and atrophic processes in the mucosa. It was found that under the increase of the concentration of HF in the air of industrial premises the probability of bronchial obstruction and deterioration of the tracheobronchial patency in aluminum smelter workers was established to elevate. [Mh] Termos MeSH primário: Poluentes Ocupacionais do Ar Alumínio Bronquite Crônica Indústria Química Doenças Profissionais Doença Pulmonar Obstrutiva Crônica [Mh] Termos MeSH secundário: Aerossóis/efeitos adversos Aerossóis/análise Aerossóis/química Poluentes Ocupacionais do Ar/análise Poluentes Ocupacionais do Ar/toxicidade Alumínio/análise Alumínio/química Bronquite Crônica/epidemiologia Bronquite Crônica/etiologia Bronquite Crônica/prevenção & controle Indústria Química/métodos Indústria Química/normas Seres Humanos Masculino Meia-Idade Doenças Profissionais/epidemiologia Doenças Profissionais/etiologia Doenças Profissionais/prevenção & controle Exposição Ocupacional/efeitos adversos Exposição Ocupacional/análise Exposição Ocupacional/prevenção & controle Doença Pulmonar Obstrutiva Crônica/epidemiologia Doença Pulmonar Obstrutiva Crônica/etiologia Doença Pulmonar Obstrutiva Crônica/prevenção & controle Sibéria/epidemiologia Tempo [Pt] Tipo de publicação: JOURNAL ARTICLE [Nm] Nome de substância: 0 (Aerosols); 0 (Air Pollutants, Occupational); CPD4NFA903 (Aluminum) [Em] Mês de entrada: 1803 [Cu] Atualização por classe: 180309 [Lr] Data última revisão: 180309 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 180216 [St] Status: MEDLINE

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[PMID]: 29446290 [Au] Autor: Shayakhmetov SV; Lisetskaya LG; Meshchakova NM; Merinov AV [Ti] Título: [Hygienic assessment of toxic dust factor at the aluminium smelter in Eastern Siberia]. [So] Source: Gig Sanit;95(12):1155-60, 2016. [Is] ISSN: 0016-9900 [Cp] País de publicação: Russia (Federation) [La] Idioma: rus [Ab] Resumo: There is presented the assessment of priority toxic matters in the air of working zone for basic occupations of aluminum smelting by electrolysis. There are presented results of different production technologies. There are presented the results of the physical-chemical analysis of the morphology and composition of produced toxic-dust complexes. [Mh] Termos MeSH primário: Poluentes Ocupacionais do Ar Alumínio Indústria Química Poeira/análise [Mh] Termos MeSH secundário: Poluentes Ocupacionais do Ar/análise Poluentes Ocupacionais do Ar/toxicidade Alumínio/análise Alumínio/química Indústria Química/métodos Indústria Química/normas Misturas Complexas/análise Misturas Complexas/toxicidade Eletrólise/métodos Seres Humanos Ciência dos Materiais/métodos Exposição Ocupacional/efeitos adversos Exposição Ocupacional/análise Exposição Ocupacional/prevenção & controle Saúde do Trabalhador Sibéria/epidemiologia [Pt] Tipo de publicação: JOURNAL ARTICLE [Nm] Nome de substância: 0 (Air Pollutants, Occupational); 0 (Complex Mixtures); 0 (Dust); CPD4NFA903 (Aluminum) [Em] Mês de entrada: 1803 [Cu] Atualização por classe: 180309 [Lr] Data última revisão: 180309 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 180216 [St] Status: MEDLINE

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[PMID]: 29446289 [Au] Autor: Sudeikina NA; Kurenkova GV; Lemeshevskaya EP [Ti] Título: [The impact of harmful occupational factors on the morbidity rate of workers of the railway-car repair plant]. [So] Source: Gig Sanit;95(12):1150-4, 2016. [Is] ISSN: 0016-9900 [Cp] País de publicação: Russia (Federation) [La] Idioma: rus [Ab] Resumo: The rail transport is the one of the leading sectors of the national economy. More than 50% of the employees of the enterprises of the railway complex work under the unfavourable impact of hazardous and dangerous substances and occupational factors. In the literature issues of working conditions and health of employees of railway carrepairing plant are hardly highlighted. The aim of the study is the evaluation of the morbidity rate shaped under the influence of harmful occupational factors for the elaboration of preventive measures. In the work there were used generally accepted methods of hygienic studies, analysis of morbidity rate with temporary disability (TD), according to records of periodic medical examinations, occupational prevalence. The railway car-repairing plant was established to be characterized by the complex of harmful factors of the working environment and labor process: noise, local vibration, industrial aerosols of complex composition, chemicals, low light, hardness of the labor process. The levels of incidence with temporal disability in the studied groups, depending on the work seniority in the harmful labor conditions, significantly decrease with the experience from 5 to 9 years and increase with the experience more than 10 years. Executed in-depth analysis as of the both morbidity rate and TD, as well results of periodic medical examinations of workers of main shops shows that overall indices of the morbidity rate and TD are significantly higher than in the comparison group; levels of the morbidity rate and TD in the observed groups significantly decline depending on the length of service in hazardous working conditions with a length of the experience offrom 5 to 9 years and increase with the increase in the length of experience of 10 years or more. In the structure of morbidity and TD leading positions are occupied by diseases of the respiratory system, musculoskeletal system and connective tissue, circulatory system and digestive system, diseases of the eye and its appendages. The health damage risk coefficients in the studied groups of workers and the average losses of working time due to the morbidity with TD per 1 employee in all shops are higher than those in the comparison group. The level of the occupational morbidity rate is very low. Harmful working conditions contribute to the development of general and occupationally related diseases. [Mh] Termos MeSH primário: Indústrias Doenças Profissionais Ferrovias [Mh] Termos MeSH secundário: Seres Humanos Incidência Indústrias/métodos Indústrias/normas Indústrias/estatística & dados numéricos Doenças Profissionais/epidemiologia Doenças Profissionais/etiologia Doenças Profissionais/prevenção & controle Exposição Ocupacional/efeitos adversos Exposição Ocupacional/análise Exposição Ocupacional/prevenção & controle Ferrovias/instrumentação Ferrovias/métodos Medição de Risco/métodos Medição de Risco/normas Fatores de Risco Sibéria/epidemiologia [Pt] Tipo de publicação: JOURNAL ARTICLE [Em] Mês de entrada: 1803 [Cu] Atualização por classe: 180309 [Lr] Data última revisão: 180309 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 180216 [St] Status: MEDLINE

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2	and or and not		PalavrasDescritor de assuntoDescritor de assunto primárioLimitesAutorPalavras do títuloPalavras do resumoIdiomaPaís de publicaçãoNome de substânciaNome de pessoa como assuntoRevistaAssunto de RevistaISSNTipo de publicaçãoIdentificador únicoMês de entradaAno de publicaçãoTexto completoAtualização por classeCategoria DeCSCategoria DeCS explodidaCategoria CID-10SubSetsPais de AfiliaçãoAfiliaçãoAfiliação 2
3	and or and not		PalavrasDescritor de assuntoDescritor de assunto primárioLimitesAutorPalavras do títuloPalavras do resumoIdiomaPaís de publicaçãoNome de substânciaNome de pessoa como assuntoRevistaAssunto de RevistaISSNTipo de publicaçãoIdentificador únicoMês de entradaAno de publicaçãoTexto completoAtualização por classeCategoria DeCSCategoria DeCS explodidaCategoria CID-10SubSetsPais de AfiliaçãoAfiliaçãoAfiliação 2

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