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[PMID]:29258634
[Au] Autor:Horner K
[Ti] Título:New Regulations on X-Ray Use: Likely Implications of IRR17 and IRMER18.
[So] Source:Prim Dent J;6(4):19-21, 2017 Dec 01.
[Is] ISSN:2050-1684
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Professor Keith Horner, co-editor of FGDP(UK)'s selection criteria for dental radiography, analyses what the ionising radiation regulations 2017 and draft ionising radiation (medical exposure) regulations 2018 mean for dentists and dental practice teams.
[Mh] Termos MeSH primário: Odontologia Geral
Proteção Radiológica/legislação & jurisprudência
Radiografia Dentária
[Mh] Termos MeSH secundário: Seres Humanos
Garantia da Qualidade dos Cuidados de Saúde
Dose de Radiação
Reino Unido
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180227
[Lr] Data última revisão:
180227
[Sb] Subgrupo de revista:D
[Da] Data de entrada para processamento:171221
[St] Status:MEDLINE
[do] DOI:10.1308/205016817822230184


  2 / 16393 MEDLINE  
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[PMID]:29398043
[Au] Autor:Prister BS; Vinogradskaya VD; Lev TD; Talerko MM; Garger EK; Onishi Y; Tischenko OG
[Ad] Endereço:Institute for Safety Problem of Nuclear Power Plants, NAS of Ukraine, 12 Lysogirska Str., 03028 Kyiv, Ukraine.
[Ti] Título:Preventive radioecological assessment of territory for optimization of monitoring and countermeasures after radiation accidents.
[So] Source:J Environ Radioact;184-185:140-151, 2018 Apr.
[Is] ISSN:1879-1700
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:A methodology of a preventive radioecological assessment of the territory has been developed for optimizing post-emergency monitoring and countermeasure implementation in an event of a severe radiation accident. Approaches and main stages of integrated radioecological zoning of the territory are described. An algorithm for the assessment of the potential radioecological criticality (sensitivity) of the area is presented. The proposed approach is validated using data of the dosimetric passportization in Ukraine after the Chernobyl accident for the test site settlements.
[Mh] Termos MeSH primário: Monitoramento de Radiação
Liberação Nociva de Radioativos/prevenção & controle
[Mh] Termos MeSH secundário: Acidente Nuclear de Chernobyl
Proteção Radiológica/métodos
Ucrânia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180220
[Lr] Data última revisão:
180220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180206
[St] Status:MEDLINE


  3 / 16393 MEDLINE  
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[PMID]:29368465
[Au] Autor:Zwicker K
[Ti] Título:Experimenting with Radium Therapy: In the Laboratory & the Clinic.
[So] Source:Clio Med;95:194-214, 2016.
[Is] ISSN:0045-7183
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Mh] Termos MeSH primário: Centros Médicos Acadêmicos/história
Neoplasias/história
Radioterapia/história
Rádio (Elemento)/história
[Mh] Termos MeSH secundário: História do Século XIX
História do Século XX
Seres Humanos
Laboratórios/história
Neoplasias/radioterapia
Proteção Radiológica/história
Estados Unidos
[Pt] Tipo de publicação:HISTORICAL ARTICLE; JOURNAL ARTICLE
[Nm] Nome de substância:
W90AYD6R3Q (Radium)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180215
[Lr] Data última revisão:
180215
[Sb] Subgrupo de revista:IM; QIS
[Da] Data de entrada para processamento:180126
[St] Status:MEDLINE


  4 / 16393 MEDLINE  
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[PMID]:28749810
[Au] Autor:Waterman G; Kase K; Orion I; Broisman A; Milstein O
[Ad] Endereço:*Department of Research & Development, StemRad, Ltd., 6 Raoul Wallenberg St. 1st Floor Tel Aviv 6971905, Israel; †Department of Nuclear Engineering, Ben-Gurion University of the Negev. P.O.B. 653, Beer-Sheva 84105, Israel.
[Ti] Título:Selective Shielding of Bone Marrow: An Approach to Protecting Humans from External Gamma Radiation.
[So] Source:Health Phys;113(3):195-208, 2017 09.
[Is] ISSN:1538-5159
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The current feasibility of protecting emergency responders through bone marrow selective shielding is highlighted in the recent OECD/NEA report on severe accident management. Until recently, there was no effective personal protection from externally penetrating gamma radiation. In Chernobyl, first-responders wore makeshift lead sheeting, whereas in Fukushima protective equipment from gamma radiation was not available. Older protective solutions that use thin layers of shielding over large body surfaces are ineffective for energetic gamma radiation. Acute exposures may result in Acute Radiation Syndrome where the survival-limiting factor up to 10 Gy uniform, homogeneous exposure is irreversible bone marrow damage. Protracted, lower exposures may result in malignancies of which bone marrow is especially susceptible, being compounded by leukemia's short latency time. This highlights the importance of shielding bone marrow for preventing both deterministic and stochastic effects. Due to the extraordinary regenerative potential of hematopoietic stem cells, to effectively prevent the deterministic effects of bone marrow exposure, it is sufficient to protect only a small fraction of this tissue. This biological principle allows for a new class of equipment providing unprecedented attenuation of radiation to select marrow-rich regions, deferring the hematopoietic sub-syndrome of Acute Radiation Syndrome to much higher doses. As approximately half of the body's active bone marrow resides within the pelvis region, shielding this area holds great promise for preventing the deterministic effects of bone marrow exposure and concomitantly reducing stochastic effects. The efficacy of a device that selectively shields this region and other radiosensitive organs in the abdominal area is shown here.
[Mh] Termos MeSH primário: Medula Óssea/efeitos da radiação
Raios gama/efeitos adversos
Proteção Radiológica/instrumentação
[Mh] Termos MeSH secundário: Síndrome Aguda da Radiação/prevenção & controle
Socorristas
Engenharia
Seres Humanos
Método de Monte Carlo
Imagens de Fantasmas
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:180214
[Lr] Data última revisão:
180214
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170728
[St] Status:MEDLINE
[do] DOI:10.1097/HP.0000000000000688


  5 / 16393 MEDLINE  
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[PMID]:29275573
[Au] Autor:Guo XL; Li G; Cheng Y; Yu Q; Wang H; Zhang ZY
[Ad] Endereço:Department of Oral and Maxillofacial Radiology, Peking University School and Hospital of Stomatology & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology, Beijing 100081, China.
[Ti] Título:[Standards and guidelines of radiation protection and safety in dental X-ray examinations].
[So] Source:Zhonghua Kou Qiang Yi Xue Za Zhi;52(12):762-772, 2017 Dec 09.
[Is] ISSN:1002-0098
[Cp] País de publicação:China
[La] Idioma:chi
[Ab] Resumo:With the rapid development of imaging technology, the application of dental imaging in diagnosis, treatment planning, intraoperative surgical navigation, monitoring of treatment or lesion development and assessment of treatment outcomes is playing an essential role in oral healthcare. The increased total number of dental X-ray examinations is accompanied by a relatively significant increase in collective dose to patients as well as to dental healthcare workers, which is harmful to human bodies to a certain degree. Some radiation protection standards and guidelines in dental radiology have been published in European countries, US, Canada and Australia, etc. Adherence to these standards and guidelines helps to achieve images with diagnostic quality and avoid unnecessary and repeated exposures. However, no radiation protection standard or guideline with regard to dental X-ray examinations has been put in force so far in mainland China. Therefore, a literature review on available radiation protection standards and guidelines was conducted to provide reference to the development of radiation protection standards or guidelines in mainland China.
[Mh] Termos MeSH primário: Guias de Prática Clínica como Assunto
Exposição à Radiação/normas
Proteção Radiológica/normas
Radiografia Dentária/normas
[Mh] Termos MeSH secundário: China
Seres Humanos
Exposição Ocupacional/normas
Dose de Radiação
Padrões de Referência
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180209
[Lr] Data última revisão:
180209
[Sb] Subgrupo de revista:D; IM
[Da] Data de entrada para processamento:171226
[St] Status:MEDLINE
[do] DOI:10.3760/cma.j.issn.1002-0098.2017.12.011


  6 / 16393 MEDLINE  
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[PMID]:29232080
[Au] Autor:Yepes JF
[Ti] Título:Radiation Safety and Protection in Pediatric Dentistry: Rectangular Collimation.
[So] Source:J Indiana Dent Assoc;95(2):24-7, 2016.
[Is] ISSN:0019-6568
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Odontopediatria
Proteção Radiológica/normas
Radiografia Dentária
[Mh] Termos MeSH secundário: Desenho de Equipamento
Seres Humanos
Dose de Radiação
Fatores de Risco
Estados Unidos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180115
[Lr] Data última revisão:
180115
[Sb] Subgrupo de revista:D
[Da] Data de entrada para processamento:171213
[St] Status:MEDLINE


  7 / 16393 MEDLINE  
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[PMID]:28463588
[Au] Autor:Judge JL; Lacy SH; Ku WY; Owens KM; Hernady E; Thatcher TH; Williams JP; Phipps RP; Sime PJ; Kottmann RM
[Ad] Endereço:a Department of Environmental Medicine, University of Rochester, Rochester, New York.
[Ti] Título:The Lactate Dehydrogenase Inhibitor Gossypol Inhibits Radiation-Induced Pulmonary Fibrosis.
[So] Source:Radiat Res;188(1):35-43, 2017 07.
[Is] ISSN:1938-5404
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Exposure of the lung to ionizing radiation that occurs in radiotherapy, as well as after accidental or intentional mass casualty incident can result in pulmonary fibrosis, which has few treatment options. Pulmonary fibrosis is characterized by an accumulation of extracellular matrix proteins that create scar tissue. Although the mechanisms leading to radiation-induced pulmonary fibrosis remain poorly understood, one frequent observation is the activation of the profibrotic cytokine transforming growth factor-beta (TGF-ß). Our laboratory has shown that the metabolite lactate activates latent TGF-ß by a reduction in extracellular pH. We recently demonstrated that lactate dehydrogenase-A (LDHA), the enzyme that produces lactate, is upregulated in patients with radiation-induced pulmonary fibrosis. Furthermore, genetic silencing of LDHA or pharmacologic inhibition using the LDHA inhibitor gossypol prevented radiation-induced extracellular matrix secretion in vitro through inhibition of TGF-ß activation. In the current study, we hypothesized that LDHA inhibition in vivo prevents radiation-induced pulmonary fibrosis. To test this hypothesis, C57BL/6 mice received 5 Gy total-body irradiation plus 10 Gy thoracic irradiation from a Cs source to induce pulmonary fibrosis. Starting at 4 weeks postirradiation, mice were treated with 5 mg/kg of the LDHA inhibitor gossypol or vehicle daily until sacrifice at 26 weeks postirradiation. Exposure to radiation resulted in pulmonary fibrosis, characterized by an increase in collagen content, fibrosis area, extracellular matrix gene expression and TGF-ß activation. Irradiated mice treated with gossypol had significantly reduced fibrosis outcomes, including reduced collagen content in the lungs, reduced expression of active TGF-ß, LDHA and the transcription factor hypoxia-inducible factor-1 alpha (HIF-1α). These findings suggest that inhibition of LDHA protects against radiation-induced pulmonary fibrosis, and may be a novel therapeutic strategy for radiation-induced pulmonary fibrosis.
[Mh] Termos MeSH primário: Gossipol/administração & dosagem
L-Lactato Desidrogenase/antagonistas & inibidores
Fibrose Pulmonar/imunologia
Fibrose Pulmonar/prevenção & controle
Pneumonite por Radiação/imunologia
Pneumonite por Radiação/prevenção & controle
[Mh] Termos MeSH secundário: Animais
Citocinas/imunologia
Relação Dose-Resposta a Droga
Masculino
Camundongos
Camundongos Endogâmicos C57BL
Fibrose Pulmonar/patologia
Dose de Radiação
Pneumonite por Radiação/patologia
Proteção Radiológica/métodos
Tolerância a Radiação/efeitos dos fármacos
Protetores contra Radiação/administração & dosagem
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Cytokines); 0 (Radiation-Protective Agents); EC 1.1.1.27 (L-Lactate Dehydrogenase); KAV15B369O (Gossypol)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:180112
[Lr] Data última revisão:
180112
[Sb] Subgrupo de revista:IM; S
[Da] Data de entrada para processamento:170503
[St] Status:MEDLINE
[do] DOI:10.1667/RR14620.1


  8 / 16393 MEDLINE  
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[PMID]:29199791
[Au] Autor:Larjava H; Aarnio J
[Ti] Título:Radiation protection - still necessary?
[So] Source:Duodecim;132(24):2324-8, 2016.
[Is] ISSN:0012-7183
[Cp] País de publicação:Finland
[La] Idioma:eng
[Ab] Resumo:Knowledge about the effects of small doses of radiation on health is accumulating, and for example the maximum level of occupational exposure allowed for the lens of the eye will be lowered in the next radiation law. Radiographic examinations are carried out at various departments in a hospital. Although the numbers of examinations have decreased in Finland, the examinations are more complex, and more radiation than before as well as longer fluoroscopy times are utilized in them. The guidelines for radiation are consistent despite the fact that there is large variation in the radiologic studies and procedures performed at different departments.
[Mh] Termos MeSH primário: Exposição Ocupacional/prevenção & controle
Exposição à Radiação/prevenção & controle
Proteção Radiológica
[Mh] Termos MeSH secundário: Olho/efeitos da radiação
Finlândia
Fluoroscopia
Seres Humanos
Dose de Radiação
Radiometria/métodos
Fatores de Risco
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180108
[Lr] Data última revisão:
180108
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171205
[St] Status:MEDLINE


  9 / 16393 MEDLINE  
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[PMID]:29206792
[Au] Autor:McNabb DC; Jennings JM; Levy DL; Miner TM; Yang CC; Kim RH
[Ad] Endereço:Raleigh Orthopaedic Clinic, Raleigh, North Carolina.
[Ti] Título:Direct Anterior Hip Replacement Does Not Pose Undue Radiation Exposure Risk to the Patient or Surgeon.
[So] Source:J Bone Joint Surg Am;99(23):2020-2025, 2017 Dec 06.
[Is] ISSN:1535-1386
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The fluoroscopically assisted direct anterior approach for total hip arthroplasty has gained interest in recent years. One of the perceived advantages is the use of fluoroscopy to aid in the positioning of implants. The purpose of this study was to measure the radiation entrance surface dose to anatomically important areas of both patients and surgeons during direct anterior approach total hip arthroplasty. METHODS: Radiation dosimetry badges were placed at the sternal notch and pubic symphysis of 50 patients undergoing direct anterior approach total hip arthroplasty. Badges were also placed on the surgeons outside of their lead aprons at the level of the thyroid. Three fellowship-trained arthroplasty surgeons were involved in the study. Radiation exposure of each badge was measured after each case (surgeon and patient). The cumulative dose was also calculated for the surgeons. To limit surgeon bias during the study, 50 consecutive direct anterior approach total hip arthroplasties that occurred prior to this study were analyzed for total fluoroscopic dose and time and served as a control group. RESULTS: Forty-five subjects met study criteria. In the study group, 1 patient had a detectable thyroid exposure equal to 1 mrem. Seven patients had a detectable radiation entrance surface dose at the pubic symphysis (range, 1 to 7 mrem). No radiation entrance surface dose was detectable in the remaining 44 patients at the sternal notch and 38 patients at the pubic symphysis. Surgeons in the study did not experience a detectable radiation entrance surface dose. The mean fluoroscopic time was 13.72 seconds (range, 6.7 to 28.7 seconds). The mean patient radiation exposure was 178 mrem (range, 54 to 526 mrem). CONCLUSIONS: This study demonstrates that during direct anterior approach total hip arthroplasty, the mean patient entrance surface dose at the pubic symphysis and the sternal notch is not detectable in most patients. The mean patient exposure in this study during direct anterior approach total hip arthroplasty was 178 mrem, which is less than a single pelvic radiograph (600 mrem). No surgeon in our study demonstrated a detectable radiation entrance surface dose. Our data suggest that direct anterior approach total hip arthroplasty typically results in a negligible or very low dose of absorbed radiation exposure to the patient and the surgeon. CLINICAL RELEVANCE: We believe this study to have clinical relevance because both patients and surgeons have evidence that utilization of fluoroscopy during direct anterior total hip replacement places both parties at a relatively low radiation exposure risk.
[Mh] Termos MeSH primário: Artroplastia de Quadril/métodos
Exposição Ocupacional
Exposição à Radiação
Cirurgiões
[Mh] Termos MeSH secundário: Adulto
Idoso
Idoso de 80 Anos ou mais
Feminino
Fluoroscopia
Seres Humanos
Masculino
Meia-Idade
Dose de Radiação
Proteção Radiológica
Radiometria
Risco
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171208
[Lr] Data última revisão:
171208
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171206
[St] Status:MEDLINE
[do] DOI:10.2106/JBJS.17.00351


  10 / 16393 MEDLINE  
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[PMID]:27778526
[Au] Autor:Wojcik A; Oestreicher U; Barrios L; Vral A; Terzoudi G; Ainsbury E; Rothkamm K; Trompier F; Kulka U
[Ad] Endereço:a Department of Molecular Biosciences , Stockholm University, Stockholm, Sweden and Jan Kochanowski University, Institute for Biology , Kielce , Poland .
[Ti] Título:The RENEB operational basis: complement of established biodosimetric assays.
[So] Source:Int J Radiat Biol;93(1):15-19, 2017 01.
[Is] ISSN:1362-3095
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:PURPOSE: To set up an operational basis of the Realizing the European Network of Biodosimetry (RENEB) network within which the application of seven established biodosimetric tools (the dicentric assay, the FISH assay, the micronucleus assay, the PCC assay, the gamma-H2AX assay, electron paramagnetic resonance and optically stimulated luminescence) will be compared and standardized among the participating laboratories. METHODOLOGY: Two intercomparisons were organized where blood samples and smartphone components were irradiated, coded and sent out to participating laboratories for dosimetric analysis. Moreover, an accident exercise was organized during which each RENEB partner had the chance to practice the procedure of activating the network and to handle large amounts of dosimetric results. RESULTS: All activities were carried out as planned. Overall, the precision of dose estimates improved between intercomparisons 1 and 2, clearly showing the value of running such regular activities. CONCLUSIONS: The RENEB network is fully operational and ready to act in case of a major radiation emergency. Moreover, the high capacity for analyzing radiation-induced damage in cells and personal electronic devices makes the network suitable for large-scale analyses of low doses effects, where high numbers of samples must be scored in order to detect weak effects.
[Mh] Termos MeSH primário: Bioensaio/métodos
Exposição à Radiação/análise
Lesões por Radiação/prevenção & controle
Monitoramento de Radiação/métodos
Proteção Radiológica/métodos
[Mh] Termos MeSH secundário: Emergências
Europa (Continente)
Seres Humanos
Laboratórios/organização & administração
Objetivos Organizacionais
Exposição à Radiação/prevenção & controle
Avaliação da Tecnologia Biomédica
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1707
[Cu] Atualização por classe:171205
[Lr] Data última revisão:
171205
[Sb] Subgrupo de revista:IM; S
[Da] Data de entrada para processamento:161026
[St] Status:MEDLINE
[do] DOI:10.1080/09553002.2016.1235296



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