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[PMID]:29415031
[Au] Autor:Tensen L; Groom RJ; Khuzwayo J; Jansen van Vuuren B
[Ad] Endereço:Centre for Ecological Genomics and Wildlife Conservation, Department of Zoology, University of Johannesburg, Johannesburg, South Africa.
[Ti] Título:The genetic tale of a recovering lion population (Panthera leo) in the Savé Valley region (Zimbabwe): A better understanding of the history and managing the future.
[So] Source:PLoS One;13(2):e0190369, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The rapid decline of the African lion (Panthera leo) has raised conservation concerns. In the Savé Valley Conservancy (SVC), in the Lowveld of Zimbabwe, lions were presumably reduced to approximately 5 to 10 individuals. After ten lions were reintroduced in 2005, the population has recovered to over 200 lions in 2016. Although the increase of lions in the SVC seems promising, a question remains whether the population is genetically viable, considering their small founding population. In this study, we document the genetic diversity in the SVC lion population using both mitochondrial and nuclear genetic markers, and compare our results to literature from other lion populations across Africa. We also tested whether genetic diversity is spatially structured between lion populations residing on several reserves in the Lowveld of Zimbabwe. A total of 42 lions were genotyped successfully for 11 microsatellite loci. We confirmed that the loss of allelic richness (probably resulting from genetic drift and small number of founders) has resulted in low genetic diversity and inbreeding. The SVC lion population was also found to be genetically differentiated from surrounding population, as a result of genetic drift and restricted natural dispersal due to anthropogenic barriers. From a conservation perspective, it is important to avoid further loss of genetic variability in the SVC lion population and maintain evolutionary potential required for future survival. Genetic restoration through the introduction of unrelated individuals is recommended, as this will increase genetic heterozygosity and improve survival and reproductive fitness in populations.
[Mh] Termos MeSH primário: Leões/genética
[Mh] Termos MeSH secundário: Animais
Conservação dos Recursos Naturais
Zimbábue
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180309
[Lr] Data última revisão:
180309
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180208
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0190369


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[PMID]:28453843
[Au] Autor:Uprety P; Lindsey JC; Levin MJ; Rainwater-Lovett K; Ziemniak C; Bwakura-Dangarembizix M; Kaplan SS; Nelson M; Zadzilka A; Weinberg A; Persaud D
[Ad] Endereço:W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
[Ti] Título:Inflammation and Immune Activation in Antiretroviral-Treated Human Immunodeficiency Virus Type 1-Infected African Infants and Rotavirus Vaccine Responses.
[So] Source:J Infect Dis;215(6):928-932, 2017 03 15.
[Is] ISSN:1537-6613
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Biomarkers of inflammation and immune activation were correlated with rotavirus vaccine responses in 68 human immunodeficiency virus type 1 (HIV-1)­infected (and 116 HIV-exposed but uninfected (HEU) African infants receiving pentavalent rotavirus vaccine (RV5) in a clinical trial. Prevaccination, HIV-1+ infants had significantly higher concentrations of interferon γ (IFNγ), interleukin1ß, interleukin 2, interleukin 6, interleukin 10 (IL-10), and soluble CD14 compared with HEU infants. Postvaccination concentrations of neutralizing antibodies to RV5 were negatively correlated with prevaccination concentrations of IL-10 (RV5 surface proteins G1 and P1) and IFNγ (G1) in the HIV-1+ infants, whereas antirotavirus immunoglobulin A (IgA) levels were not. Heightened inflammation and immune activation in HIV-1+ infants did not alter IgA responses associated with protection from rotavirus disease.
[Mh] Termos MeSH primário: Infecções por HIV/tratamento farmacológico
Infecções por Rotavirus/prevenção & controle
Vacinas contra Rotavirus/uso terapêutico
[Mh] Termos MeSH secundário: Anticorpos Neutralizantes/sangue
Anticorpos Antivirais/sangue
Terapia Antirretroviral de Alta Atividade
Biomarcadores/sangue
Botsuana
Contagem de Linfócito CD4
Citocinas/sangue
Método Duplo-Cego
Feminino
HIV-1/imunologia
Seres Humanos
Imunoglobulina A/sangue
Lactente
Inflamação
Masculino
Análise Multivariada
Tanzânia
Zâmbia
Zimbábue
[Pt] Tipo de publicação:CLINICAL TRIAL, PHASE II; JOURNAL ARTICLE; MULTICENTER STUDY; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
0 (Antibodies, Neutralizing); 0 (Antibodies, Viral); 0 (Biomarkers); 0 (Cytokines); 0 (Immunoglobulin A); 0 (Rotavirus Vaccines)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170429
[St] Status:MEDLINE
[do] DOI:10.1093/infdis/jix060


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[PMID]:29323642
[Au] Autor:Green A
[Ti] Título:Zimbabwe post-Mugabe era: reconstructing a health system.
[So] Source:Lancet;391(10115):17-18, 2018 01 06.
[Is] ISSN:1474-547X
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Assistência à Saúde/economia
Países em Desenvolvimento
Financiamento Governamental
Setor de Assistência à Saúde/economia
[Mh] Termos MeSH secundário: Seres Humanos
Liderança
Política
Zimbábue
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180212
[Lr] Data última revisão:
180212
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180112
[St] Status:MEDLINE


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[PMID]:29227136
[Au] Autor:Ray SC; Masuka N
[Ad] Endereço:Department of Community Medicine, College of Health Sciences, University of Zimbabwe. sunanda28@hotmail.com.
[Ti] Título:Facilitators and barriers to effective primary health care in Zimbabwe.
[So] Source:Afr J Prim Health Care Fam Med;9(1):e1-e2, 2017 Nov 28.
[Is] ISSN:2071-2936
[Cp] País de publicação:South Africa
[La] Idioma:eng
[Ab] Resumo:No abstract available.
[Mh] Termos MeSH primário: Acesso aos Serviços de Saúde/estatística & dados numéricos
Atenção Primária à Saúde/métodos
Atenção Primária à Saúde/estatística & dados numéricos
[Mh] Termos MeSH secundário: Seres Humanos
Zimbábue
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180213
[Lr] Data última revisão:
180213
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171212
[St] Status:MEDLINE
[do] DOI:10.4102/phcfm.v9i1.1639


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[PMID]:28743251
[Au] Autor:Chadambuka A; Katirayi L; Muchedzi A; Tumbare E; Musarandega R; Mahomva AI; Woelk G
[Ad] Endereço:Elizabeth Glaser Pediatric AIDS Foundation, 107 King George Road, Avondale, Harare, Zimbabwe. achadambuka1@yahoo.co.uk.
[Ti] Título:Acceptability of lifelong treatment among HIV-positive pregnant and breastfeeding women (Option B+) in selected health facilities in Zimbabwe: a qualitative study.
[So] Source:BMC Public Health;18(1):57, 2017 07 25.
[Is] ISSN:1471-2458
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Zimbabwe's Ministry of Health and Child Care (MOHCC) adopted 2013 World Health Organization (WHO) prevention of mother-to-child HIV transmission (PMTCT) guidelines recommending initiation of HIV-positive pregnant and breastfeeding women (PPBW) on lifelong antiretroviral treatment (ART) irrespective of clinical stage (Option B+). Option B+ was officially launched in Zimbabwe in November 2013; however the acceptability of life-long ART and its potential uptake among women was not known. METHODS: A qualitative study was conducted at selected sites in Harare (urban) and Zvimba (rural) to explore Option B+ acceptability; barriers, and facilitators to ART adherence and service uptake. In-depth interviews (IDIs), focus group discussions (FGDs) and key informant interviews (KIIs) were conducted with PPBW, healthcare providers, and community members. All interviews were audio-recorded, transcribed, and translated; data were coded and analyzed in MaxQDA v10. RESULTS: Forty-three IDIs, 22 FGDs, and five KIIs were conducted. The majority of women accepted lifelong ART. There was however, a fear of commitment to taking lifelong medication because they were afraid of defaulting, especially after cessation of breastfeeding. There was confusion around dosage; and fear of side effects, not having enough food to take drugs, and the lack of opportunities to ask questions in counseling. Participants reported the need for strengthening community sensitization for Option B+. Facilitators included receiving a simplified pill regimen; ability to continue breastfeeding beyond 6 months like HIV-negative women; and partner, community and health worker support. Barriers included distance of health facility, non-disclosure of HIV status, poor male partner support and knowing someone who had negative experience on ART. CONCLUSIONS: This study found that Option B+ is generally accepted among PPBW as a means to strengthen their health and protect their babies. Consistent with previous literature, this study demonstrated the importance of male partner and community support in satisfactory adherence to ART and enhancing counseling techniques. Strengthening community sensitization and male knowledge is critical to encourage women to disclose their HIV status and ensure successful adherence to ART. Targeting and engaging partners of women will remain key determinants to women's acceptance and adherence on ART under Option B+.
[Mh] Termos MeSH primário: Fármacos Anti-HIV/uso terapêutico
Aleitamento Materno/psicologia
Infecções por HIV/tratamento farmacológico
Aceitação pelo Paciente de Cuidados de Saúde/psicologia
Aceitação pelo Paciente de Cuidados de Saúde/estatística & dados numéricos
Complicações Infecciosas na Gravidez/tratamento farmacológico
Gestantes/psicologia
[Mh] Termos MeSH secundário: Adulto
Feminino
Grupos Focais
Infecções por HIV/prevenção & controle
Seres Humanos
Transmissão Vertical de Doença Infecciosa/prevenção & controle
Masculino
Gravidez
Pesquisa Qualitativa
População Rural/estatística & dados numéricos
População Urbana/estatística & dados numéricos
Zimbábue
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Anti-HIV Agents)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180210
[Lr] Data última revisão:
180210
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170727
[St] Status:MEDLINE
[do] DOI:10.1186/s12889-017-4611-2


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[PMID]:29220392
[Au] Autor:Tshimanga M; Makunike-Chikwinya B; Mangwiro T; Tapiwa Gundidza P; Chatikobo P; Murenje V; Herman-Roloff A; Kilmarx PH; Holec M; Gwinji G; Mugurungi O; Murwira M; Xaba S; Barnhart S; Feldacker C
[Ad] Endereço:Zimbabwe Community Health Intervention Project (ZiCHIRe), Harare, Zimbabwe.
[Ti] Título:Safety and efficacy of the PrePex device in HIV-positive men: A single-arm study in Zimbabwe.
[So] Source:PLoS One;12(12):e0189146, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:METHODS: We aimed to determine if the adverse event (AE) rate was non-inferior to an AE rate of 2%, a rate considered the global standard of MC safety. Study procedures, AE definitions, and study staff were unchanged from previous PrePex Zimbabwe trials. After PrePex placement and removal, weekly visits assessed wound healing. Men returned on Day 90. Safety was defined as occurrence of moderate and serious clinical AEs. Efficacy was defined as ability to reach the endpoint of complete circumcision. RESULTS: Among 400 healthy, HIV-positive, consenting adults, median age was 40 years (IQR: 34, 46); 79.5% in WHO stage 2; median CD4 was 336.5c/µl (IQR: 232, 459); 337 (85%) on anti-retroviral therapy. Among 385 (96%) observed completely healed, median days to complete healing was 42 (IQR: 35-49). There was no association between time to healing and CD4 (p = 0.66). Four study-related severe AEs and no moderate AEs were reported: severe/moderate AE rate of 1.0% (95% CI: 0.27% to 2.5). This was non-inferior to 2% AEs (p = 0.0003). All AEs were device displacements resulting in surgical MC and, subsequently, complete healing. CONCLUSION: Male circumcision among healthy, HIV-positive men using PrePex is safe and effective. Reducing the barrier of HIV testing while improving counseling for safer sex practices among all MC clients could increase MC uptake and avert more HIV infections.
[Mh] Termos MeSH primário: Circuncisão Masculina/métodos
Infecções por HIV/transmissão
[Mh] Termos MeSH secundário: Adulto
Circuncisão Masculina/efeitos adversos
Seres Humanos
Masculino
Zimbábue
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180209
[Lr] Data última revisão:
180209
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171209
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0189146


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[PMID]:29272320
[Au] Autor:Adamson PC; Tafuma TA; Davis SM; Xaba S; Herman-Roloff A
[Ad] Endereço:School of Medicine, University of California San Francisco, San Francisco, California, United States of America.
[Ti] Título:A systems-based assessment of the PrePex device adverse events active surveillance system in Zimbabwe.
[So] Source:PLoS One;12(12):e0190055, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Voluntary Medical Male Circumcision (VMMC) is an effective method for HIV prevention and the World Health Organization (WHO) has recommended its expansion in 14 African countries with a high prevalence of HIV and low prevalence of male circumcision. The WHO has recently pre-qualified the PrePex device, a non-surgical male circumcision device, which reduces procedure time, can increase acceptability of VMMC, and can expand the set of potential provider cadres. The PrePex device was introduced in Zimbabwe as a way to scale-up VMMC services in the country. With the rapid scale-up of the PrePex device, as well as other similar devices, a strong surveillance system to detect adverse events (AE) is needed to monitor the safety profile of these devices. We performed a systems-based evaluation of the PrePex device AE active surveillance system in Zimbabwe. METHODS: The evaluation was based on the Centers for Disease Control and Prevention's Updated Guidelines for Evaluating Public Health Surveillance Systems. We adapted these guidelines to fit our local context. The evaluation incorporated the review of the standard operating procedures and surveillance system documents. Additionally, structured, in-person interviews were performed with key stakeholders who were users of the surveillance system at various levels. These key stakeholders were from the Ministry of Health, implementing partners, and health facilities in Harare. RESULTS: Clients were requested to return to the facility for follow-up on days 7, 14 and 49 after placement of the device. In the event of a severe AE, a standard report was generated by the health facility and relayed to the Ministry of Health Child and Care and donor agencies through predefined channels within 24 hours of diagnosis. Clinic staff reported difficulties with the amount of documentation required to follow up with clients and to report AEs. The surveillance system's acceptability among users interviewed was high, and users were motivated to identify all possible AEs related to this device. The surveillance system was purely paper-based and both duplicate and discrepant reporting forms between sites were identified. CONCLUSION: The PrePex AE active surveillance system was well accepted among participants in the health system. However, the amount of documentation which was required to follow-up with patients was a major barrier within the system, and might lead to decreased timeliness and quality of reporting. A passive surveillance system supported by electronic reporting would improve acceptance of the program.
[Mh] Termos MeSH primário: Circuncisão Masculina/métodos
Infecções por HIV/prevenção & controle
Vigilância da População
[Mh] Termos MeSH secundário: Circuncisão Masculina/efeitos adversos
Seres Humanos
Masculino
Zimbábue
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180116
[Lr] Data última revisão:
180116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171223
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0190055


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[PMID]:29253027
[Au] Autor:Panteli M; Benetos E; Dixon S
[Ad] Endereço:Centre for Digital Music, School of Electronic Engineering and Computer Science, Queen Mary University of London, London, United Kingdom.
[Ti] Título:A computational study on outliers in world music.
[So] Source:PLoS One;12(12):e0189399, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The comparative analysis of world music cultures has been the focus of several ethnomusicological studies in the last century. With the advances of Music Information Retrieval and the increased accessibility of sound archives, large-scale analysis of world music with computational tools is today feasible. We investigate music similarity in a corpus of 8200 recordings of folk and traditional music from 137 countries around the world. In particular, we aim to identify music recordings that are most distinct compared to the rest of our corpus. We refer to these recordings as 'outliers'. We use signal processing tools to extract music information from audio recordings, data mining to quantify similarity and detect outliers, and spatial statistics to account for geographical correlation. Our findings suggest that Botswana is the country with the most distinct recordings in the corpus and China is the country with the most distinct recordings when considering spatial correlation. Our analysis includes a comparison of musical attributes and styles that contribute to the 'uniqueness' of the music of each country.
[Mh] Termos MeSH primário: Música
Processamento de Sinais Assistido por Computador
[Mh] Termos MeSH secundário: Algoritmos
Benin
Botsuana
China
Análise por Conglomerados
Características Culturais
Geografia
Guiné
Seres Humanos
Linguagem
Modelos Estatísticos
Software
Sudão do Sul
Zimbábue
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180108
[Lr] Data última revisão:
180108
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171219
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0189399


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[PMID]:29073138
[Au] Autor:Shiff C
[Ad] Endereço:Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America.
[Ti] Título:Why reinvent the wheel? Lessons in schistosomiasis control from the past.
[So] Source:PLoS Negl Trop Dis;11(10):e0005812, 2017 Oct.
[Is] ISSN:1935-2735
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Schistosomiasis has been of concern to local health authorities for most of the last century, and in spite of a lack of effective chemotherapy, the disease was dealt with quite effectively in many endemic countries by snail control and environmental management [1]. Much of this work was reported in journals prior to the electronic era but, sadly, seems to have been subsequently ignored. For many years, there followed a global hiatus on schistosomiasis control, and much of the local expertise was lost, but many things have changed more recently, mainly with the advent of generic and affordable praziquantel. With the increased availability of this drug, there has been an increasing interest in readdressing schistosomes as well as other neglected tropical diseases (NTDs). The strategic approach for this had been based almost exclusively on chemotherapy. Recently, however, questions arose about this strategy with evidence that chemotherapy alone was not succeeding [2]. Additional strategies were needed, and the "Towards Elimination of Schistosomiasis" (TES) 2017 Conference in Cameroon stressed an integrated PHASE strategy. This was in line with the WHO-NTD and WHO-AFRO 2014-2020 Regional Strategy on NTDs and directed emphasis on transmission control. Subsequently, this emphasis was discussed in a comprehensive review [3] that stressed the importance of such additions to any elimination programme. In reality, this means focusing on the aquatic snail hosts where and when transmission occurs, defining other risk factors such as water contact and latrine design and identifying improved sanitation and health education as essential components for elimination. For schistosomiasis reduction during the mid-20th century, transmission control was used extensively, but these facts are not well reported. Recent reviews have attempted to cover previous research [4,5], but sadly, they have left major knowledge gaps, particularly from Africa. These omissions also occurred in a recent WHO pamphlet on molluscicides [6]. Sadly, search engines used to retrieve information appear to miss much done by 5 African research institutes active from 1950 to 1990. It seems appropriate to take a look back to a time when fieldwork was a focus of research and transmission control was emphasised.
[Mh] Termos MeSH primário: Esquistossomose/prevenção & controle
Esquistossomose/transmissão
[Mh] Termos MeSH secundário: África/epidemiologia
Animais
Congressos como Assunto
Erradicação de Doenças
Vetores de Doenças
Seres Humanos
Moluscocidas
Doenças Negligenciadas/tratamento farmacológico
Doenças Negligenciadas/prevenção & controle
Praziquantel/economia
Praziquantel/uso terapêutico
Saneamento
Esquistossomose/epidemiologia
Esquistossomose/parasitologia
Caramujos/parasitologia
Organização Mundial da Saúde
Zimbábue/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Molluscacides); 6490C9U457 (Praziquantel)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171110
[Lr] Data última revisão:
171110
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171027
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pntd.0005812


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[PMID]:29065149
[Au] Autor:Shamu T; Chimbetete C; Shawarira-Bote S; Mudzviti T; Luthy R
[Ad] Endereço:Newlands Clinic, Highlands, Harare, Zimbabwe.
[Ti] Título:Outcomes of an HIV cohort after a decade of comprehensive care at Newlands Clinic in Harare, Zimbabwe: TENART cohort.
[So] Source:PLoS One;12(10):e0186726, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Data on long-term outcomes of patients receiving antiretroviral therapy (ART) in sub-Saharan Africa are few. We describe outcomes of patients commenced on ART at Newlands Clinic between 2004 and 2006 after ≥10 years of comprehensive care including, psychosocial, adherence and food support. METHODS: In this retrospective cohort study, patient data from an electronic medical record collected during routine care were analysed. We describe baseline characteristics, virological and clinical outcomes, attrition rates, and treatment adverse effects until November 2016. We defined virological suppression as viral load <50 copies/ml and virological failure as >1000 copies/ml after ≥6 months of ART. RESULTS: We analysed data for 605 patients (67% female) who commenced ART, and were followed-up for 5819 person-years (median: 10.7 years, IQR: 10.1-11.4). Median age at ART initiation was 34 years (IQR: 17-42). Pre-ART, 129 (21.3%) patients had history of pulmonary tuberculosis (PTB). In care, 66 (11%) developed PTB, and 24 (4%) developed extrapulmonary tuberculosis. 385 (63.6%) patients experienced ≥1 adverse event, the most frequent being stavudine-induced peripheral neuropathy (n = 252, 41.7%). At database closure on 14 November 2016, 474 (78.3%) patients were still in care, 428 (90.3%) being virologically suppressed, and 21 (4.4%) failing. While 483 (79.8%) remained on first line, 122 (20.2%) were switched to second line ART. Fifty-nine patients (9.8%) were transferred to other ART facilities, 45 (7.4%) were lost to follow-up, 25 (4.1%) died, and two stopped ART. CONCLUSION: Comprehensive HIV care can result in low mortality, high retention in care and virologic suppression rates in resource limited settings.
[Mh] Termos MeSH primário: Instituições de Assistência Ambulatorial
Fármacos Anti-HIV/uso terapêutico
Assistência Integral à Saúde
Infecções por HIV/tratamento farmacológico
[Mh] Termos MeSH secundário: Adolescente
Adulto
Estudos de Coortes
Feminino
Infecções por HIV/imunologia
Infecções por HIV/virologia
Seres Humanos
Perda de Seguimento
Masculino
Adulto Jovem
Zimbábue
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-HIV Agents)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171113
[Lr] Data última revisão:
171113
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171025
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0186726



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BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde