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[PMID]:29304039
[Au] Autor:Raftery P; Condell O; Wasunna C; Kpaka J; Zwizwai R; Nuha M; Fallah M; Freeman M; Harris V; Miller M; Baller A; Massaquoi M; Katawera V; Saindon J; Bemah P; Hamblion E; Castle E; Williams D; Gasasira A; Nyenswah T
[Ad] Endereço:EVD Response Team, World Health Organization, Monrovia, Montserrado, Liberia.
[Ti] Título:Establishing Ebola Virus Disease (EVD) diagnostics using GeneXpert technology at a mobile laboratory in Liberia: Impact on outbreak response, case management and laboratory systems strengthening.
[So] Source:PLoS Negl Trop Dis;12(1):e0006135, 2018 01.
[Is] ISSN:1935-2735
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The 2014-16 Ebola Virus Disease (EVD) outbreak in West Africa highlighted the necessity for readily available, accurate and rapid diagnostics. The magnitude of the outbreak and the re-emergence of clusters of EVD cases following the declaration of interrupted transmission in Liberia, reinforced the need for sustained diagnostics to support surveillance and emergency preparedness. We describe implementation of the Xpert Ebola Assay, a rapid molecular diagnostic test run on the GeneXpert platform, at a mobile laboratory in Liberia and the subsequent impact on EVD outbreak response, case management and laboratory system strengthening. During the period of operation, site coordination, management and operational capacity was supported through a successful collaboration between Ministry of Health (MoH), World Health Organization (WHO) and international partners. A team of Liberian laboratory technicians were trained to conduct EVD diagnostics and the laboratory had capacity to test 64-100 blood specimens per day. Establishment of the laboratory significantly increased the daily testing capacity for EVD in Liberia, from 180 to 250 specimens at a time when the effectiveness of the surveillance system was threatened by insufficient diagnostic capacity. During the 18 months of operation, the laboratory tested a total of 9,063 blood specimens, including 21 EVD positives from six confirmed cases during two outbreaks. Following clearance of the significant backlog of untested EVD specimens in November 2015, a new cluster of EVD cases was detected at the laboratory. Collaboration between surveillance and laboratory coordination teams during this and a later outbreak in March 2016, facilitated timely and targeted response interventions. Specimens taken from cases during both outbreaks were analysed at the laboratory with results informing clinical management of patients and discharge decisions. The GeneXpert platform is easy to use, has relatively low running costs and can be integrated into other national diagnostic algorithms. The technology has on average a 2-hour sample-to-result time and allows for single specimen testing to overcome potential delays of batching. This model of a mobile laboratory equipped with Xpert Ebola test, staffed by local laboratory technicians, could serve to strengthen outbreak preparedness and response for future outbreaks of EVD in Liberia and the region.
[Mh] Termos MeSH primário: Surtos de Doenças/prevenção & controle
Monitoramento Epidemiológico
Doença pelo Vírus Ebola/diagnóstico
Doença pelo Vírus Ebola/epidemiologia
Unidades Móveis de Saúde
[Mh] Termos MeSH secundário: Administração de Caso
Ebolavirus/isolamento & purificação
Doença pelo Vírus Ebola/virologia
Seres Humanos
Libéria/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180210
[Lr] Data última revisão:
180210
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180106
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pntd.0006135


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[PMID]:29073124
[Au] Autor:Patel JC; George J; Vuong J; Potts CC; Bozio C; Clark TA; Thomas J; Schier J; Chang A; Waller JL; Diaz MH; Whaley M; Jenkins LT; Fuller S; Williams DE; Redd JT; Arthur RR; Taweh F; Vera Walker Y; Hardy P; Freeman M; Katawera V; Gwesa G; Gbanya MZ; Clement P; Kohar H; Stone M; Fallah M; Nyenswah T; Winchell JM; Wang X; McNamara LA; Dokubo EK; Fox LM
[Ti] Título:Rapid Laboratory Identification of Neisseria meningitidis Serogroup C as the Cause of an Outbreak - Liberia, 2017.
[So] Source:MMWR Morb Mortal Wkly Rep;66(42):1144-1147, 2017 Oct 27.
[Is] ISSN:1545-861X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:On April 25, 2017, a cluster of unexplained illness and deaths among persons who had attended a funeral during April 21-22 was reported in Sinoe County, Liberia (1). Using a broad initial case definition, 31 cases were identified, including 13 (42%) deaths. Twenty-seven cases were from Sinoe County (1), and two cases each were from Grand Bassa and Monsterrado counties, respectively. On May 5, 2017, initial multipathogen testing of specimens from four fatal cases using the Taqman Array Card (TAC) assay identified Neisseria meningitidis in all specimens. Subsequent testing using direct real-time polymerase chain reaction (PCR) confirmed N. meningitidis in 14 (58%) of 24 patients with available specimens and identified N. meningitidis serogroup C (NmC) in 13 (54%) patients. N. meningitidis was detected in specimens from 11 of the 13 patients who died; no specimens were available from the other two fatal cases. On May 16, 2017, the National Public Health Institute of Liberia and the Ministry of Health of Liberia issued a press release confirming serogroup C meningococcal disease as the cause of this outbreak in Liberia.
[Mh] Termos MeSH primário: Surtos de Doenças
Meningite Meningocócica/epidemiologia
Meningite Meningocócica/microbiologia
Neisseria meningitidis Sorogrupo C/isolamento & purificação
[Mh] Termos MeSH secundário: Serviços de Laboratório Clínico/estatística & dados numéricos
Análise por Conglomerados
Seres Humanos
Libéria/epidemiologia
Meningite Meningocócica/mortalidade
Reação em Cadeia da Polimerase em Tempo Real
Fatores de Tempo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171031
[Lr] Data última revisão:
171031
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171027
[St] Status:MEDLINE
[do] DOI:10.15585/mmwr.mm6642a5


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[PMID]:29072886
[Au] Autor:Doedeh J; Frimpong JA; Yealue KDM; Wilson HW; Konway Y; Wiah SQ; Doedeh V; Bao U; Seneh G; Gorwor L; Toe S; Ghartey E; Larway L; Gweh D; Gonotee P; Paasewe T; Tamatai G; Yarkeh J; Smith S; Brima-Davis A; Dauda G; Monger T; Gornor-Pewu LW; Lombeh S; Naiene J; Dovillie N; Korvayan M; George G; Kerwillain G; Jetoh R; Friesen S; Kinkade C; Katawera V; Amo-Addae M; George RN; Gbanya MZ; Dokubo EK
[Ti] Título:Rapid Field Response to a Cluster of Illnesses and Deaths - Sinoe County, Liberia, April-May, 2017.
[So] Source:MMWR Morb Mortal Wkly Rep;66(42):1140-1143, 2017 Oct 27.
[Is] ISSN:1545-861X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:On April 25, 2017, the Sinoe County Health Team (CHT) notified the Liberia Ministry of Health (MoH) and the National Public Health Institute of Liberia of an unknown illness among 14 persons that resulted in eight deaths in Sinoe County. On April 26, the National Rapid Response Team and epidemiologists from CDC, the World Health Organization (WHO) and the African Field Epidemiology Network (AFENET) in Liberia were deployed to support the county-led response. Measures were immediately implemented to identify all cases, ascertain the cause of illness, and control the outbreak. Illness was associated with attendance at a funeral event, and laboratory testing confirmed Neisseria meningitidis in biologic specimens from cases. The 2014-2015 Ebola virus disease (Ebola) outbreak in West Africa devastated Liberia's already fragile health system, and it took many months for the country to mount an effective response to control the outbreak. Substantial efforts have been made to strengthen Liberia's health system to prevent, detect, and respond to health threats. The rapid and efficient field response to this outbreak of N. meningitidis resulted in implementation of appropriate steps to prevent a widespread outbreak and reflects improved public health and outbreak response capacity in Liberia.
[Mh] Termos MeSH primário: Surtos de Doenças/prevenção & controle
Doença pelo Vírus Ebola/epidemiologia
Doença pelo Vírus Ebola/prevenção & controle
Cooperação Internacional
Prática de Saúde Pública
[Mh] Termos MeSH secundário: Adolescente
Adulto
Fortalecimento Institucional
Centers for Disease Control and Prevention (U.S.)
Criança
Análise por Conglomerados
Feminino
Doença pelo Vírus Ebola/mortalidade
Seres Humanos
Libéria/epidemiologia
Masculino
Meia-Idade
Neisseria meningitidis/isolamento & purificação
Estados Unidos
Organização Mundial da Saúde
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171031
[Lr] Data última revisão:
171031
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171027
[St] Status:MEDLINE
[do] DOI:10.15585/mmwr.mm6642a4


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[PMID]:29020589
[Au] Autor:Kennedy SB; Bolay F; Kieh M; Grandits G; Badio M; Ballou R; Eckes R; Feinberg M; Follmann D; Grund B; Gupta S; Hensley L; Higgs E; Janosko K; Johnson M; Kateh F; Logue J; Marchand J; Monath T; Nason M; Nyenswah T; Roman F; Stavale E; Wolfson J; Neaton JD; Lane HC; PREVAIL I Study Group
[Ad] Endereço:From the Liberian Ministry of Health, Monrovia, Liberia (S.B.K., F.B., M.K., M.B., M.J., F.K., T.N.); the University of Minnesota, Division of Biostatistics, Minneapolis (G.G., B.G., J.W., J.D.N.); GlaxoSmithKline, Rockville (R.B.), and National Institutes of Health (R.E., D.F., L.H., E.H., M.N., H.
[Ti] Título:Phase 2 Placebo-Controlled Trial of Two Vaccines to Prevent Ebola in Liberia.
[So] Source:N Engl J Med;377(15):1438-1447, 2017 10 12.
[Is] ISSN:1533-4406
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The safety and efficacy of vaccines to prevent Ebola virus disease (EVD) were unknown when the incidence of EVD was peaking in Liberia. METHODS: We initiated a randomized, placebo-controlled, phase 3 trial of the chimpanzee adenovirus 3 vaccine (ChAd3-EBO-Z) and the recombinant vesicular stomatitis virus vaccine (rVSV∆G-ZEBOV-GP) in Liberia. A phase 2 subtrial was embedded to evaluate safety and immunogenicity. Because the incidence of EVD declined in Liberia, the phase 2 component was expanded and the phase 3 component was eliminated. RESULTS: A total of 1500 adults underwent randomization and were followed for 12 months. The median age of the participants was 30 years; 36.6% of the participants were women. During the week after the administration of vaccine or placebo, adverse events occurred significantly more often with the active vaccines than with placebo; these events included injection-site reactions (in 28.5% of the patients in the ChAd3-EBO-Z group and 30.9% of those in the rVSV∆G-ZEBOV-GP group, as compared with 6.8% of those in the placebo group), headache (in 25.1% and 31.9%, vs. 16.9%), muscle pain (in 22.3% and 26.9%, vs. 13.3%), feverishness (in 23.9% and 30.5%, vs. 9.0%), and fatigue (in 14.0% and 15.4%, vs. 8.8%) (P<0.001 for all comparisons); these differences were not seen at 1 month. Serious adverse events within 12 months after injection were seen in 40 participants (8.0%) in the ChAd3-EBO-Z group, in 47 (9.4%) in the rVSV∆G-ZEBOV-GP group, and in 59 (11.8%) in the placebo group. By 1 month, an antibody response developed in 70.8% of the participants in the ChAd3-EBO-Z group and in 83.7% of those in the rVSV∆G-ZEBOV-GP group, as compared with 2.8% of those in the placebo group (P<0.001 for both comparisons). At 12 months, antibody responses in participants in the ChAd3-EBO-Z group (63.5%) and in those in the rVSV∆G-ZEBOV-GP group (79.5%) remained significantly greater than in those in the placebo group (6.8%, P<0.001 for both comparisons). CONCLUSIONS: A randomized, placebo-controlled phase 2 trial of two vaccines that was rapidly initiated and completed in Liberia showed the capability of conducting rigorous research during an outbreak. By 1 month after vaccination, the vaccines had elicited immune responses that were largely maintained through 12 months. (Funded by the National Institutes of Allergy and Infectious Diseases and the Liberian Ministry of Health; PREVAIL I ClinicalTrials.gov number, NCT02344407 .).
[Mh] Termos MeSH primário: Vacinas contra Ebola/efeitos adversos
Vacinas contra Ebola/imunologia
Ebolavirus/imunologia
Doença pelo Vírus Ebola/prevenção & controle
[Mh] Termos MeSH secundário: Adenoviridae
Adulto
Animais
Surtos de Doenças
Método Duplo-Cego
Feminino
Febre/etiologia
Soropositividade para HIV/complicações
Cefaleia/etiologia
Doença pelo Vírus Ebola/complicações
Doença pelo Vírus Ebola/imunologia
Seres Humanos
Injeções Intramusculares/efeitos adversos
Libéria
Masculino
Mialgia/etiologia
Pan troglodytes
RNA Viral/sangue
Reação em Cadeia da Polimerase Via Transcriptase Reversa
Vesiculovirus
[Pt] Tipo de publicação:CLINICAL TRIAL, PHASE II; COMPARATIVE STUDY; JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Ebola Vaccines); 0 (RNA, Viral)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171019
[Lr] Data última revisão:
171019
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171012
[Cl] Clinical Trial:ClinicalTrial
[St] Status:MEDLINE
[do] DOI:10.1056/NEJMoa1614067


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[PMID]:28920640
[Au] Autor:Hoyt DB
[Ti] Título:Looking forward ­ April 2017.
[So] Source:Bull Am Coll Surg;102(4):9-10, 2017 04.
[Is] ISSN:0002-8045
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Controle de Doenças Transmissíveis/organização & administração
Surtos de Doenças/prevenção & controle
Doença pelo Vírus Ebola/epidemiologia
Doença pelo Vírus Ebola/prevenção & controle
Sociedades Médicas
[Mh] Termos MeSH secundário: Saúde Global
Seres Humanos
Libéria/epidemiologia
Guias de Prática Clínica como Assunto
Roupa de Proteção
Estados Unidos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171010
[Lr] Data última revisão:
171010
[Sb] Subgrupo de revista:H
[Da] Data de entrada para processamento:170919
[St] Status:MEDLINE


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[PMID]:28837554
[Au] Autor:Mayrhuber EA; Niederkrotenthaler T; Kutalek R
[Ad] Endereço:Unit Medical Anthropology and Global Health, Department of Social and Preventive Medicine, Center for Public Health, Medical University of Vienna, Kinderspitalgasse 15, Vienna, Austria.
[Ti] Título:"We are survivors and not a virus:" Content analysis of media reporting on Ebola survivors in Liberia.
[So] Source:PLoS Negl Trop Dis;11(8):e0005845, 2017 Aug.
[Is] ISSN:1935-2735
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The Ebola virus disease epidemic between 2013 and 2016 in West Africa was unprecedented. It resulted in approximately 28.000 cases and 10.000 Ebola survivors. Many survivors face social, economic and health-related predicaments and media reporting is crucially important in infectious disease outbreaks. However, there is little research on reporting of the social situation of Ebola survivors in Liberia. METHODS: The study used a mixed methods approach and analysed media reports from the Liberian Daily Observer (DOL), a daily newspaper available online in English. We were interested to know how the situation of Ebola survivors was portrayed; in what way issues such as stigma and discrimination were addressed; and which stigma reduction interventions were covered and how. We included all articles on the situation of Ebola survivors in the quantitative and in-depth qualitative analysis published between April 2014 and March 2016. RESULTS: The DOL published 148 articles that portrayed the social situation of Ebola survivors between the 24 months observation period. In these articles, Ebola survivors were often defined beyond biological terms, reflecting on a broader social definition of survivorship. Survivorship was associated with challenges such as suffering from after-effects, social and economic consequences and psychological distress. Almost 50% of the articles explicitly mentioned stigmatisation in their reporting on Ebola survivors. This was contextualised in untrustworthiness towards international responses and the local health care system and inconclusive knowledge on cures and transmission routes. In the majority of DOL articles stigma reduction and engaging survivors in the response was reported as crucially important. DISCUSSION: Reporting in the DOL was educational-didactical and well-balanced in terms of disseminating available medical knowledge and reflecting the social situation of Ebola survivors. While the articles contextualised factors contributing to stigmatisation throughout the reporting, journalistic scrutiny regarding effectiveness of interventions by government and NGOs was missing.
[Mh] Termos MeSH primário: Epidemias
Doença pelo Vírus Ebola
Meios de Comunicação de Massa
Estigma Social
Sobreviventes
[Mh] Termos MeSH secundário: Doença pelo Vírus Ebola/epidemiologia
Seres Humanos
Libéria/epidemiologia
Meios de Comunicação de Massa/normas
Meios de Comunicação de Massa/estatística & dados numéricos
Fatores Sociológicos
Sobreviventes/psicologia
Sobreviventes/estatística & dados numéricos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:171010
[Lr] Data última revisão:
171010
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170825
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pntd.0005845


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[PMID]:28822213
[Au] Autor:Hamer MJM; Reed PL; Greulich JD; Beadling CW
[Ad] Endereço:Center for Global Health Engagement, Uniformed Services University, Bethesda, Maryland; Department of Emergency Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland; National Center for the Study of Preparedness and Catastrophic Event Response, Johns Hopkins University School o
[Ti] Título:Liberia national disaster preparedness coordination exercise: Implementing lessons learned from the West African disaster preparedness initiative.
[So] Source:Am J Disaster Med;12(1):35-41, 2017.
[Is] ISSN:1932-149X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: In light of the recent Ebola outbreak, there is a critical need for effective disaster management systems in Liberia and other West African nations. To this end, the West Africa Disaster Preparedness Initiative held a disaster management exercise in conjunction with the Liberian national government on November 24-25, 2015. DESIGN: During this tabletop exercise (TTX), interactions within and between the 15 counties and the Liberian national government were conducted and observed to refine and validate the county and national standard operating procedures (SOPs). SETTING: The exercise took place in three regional locations throughout Liberia: Monrovia, Buchanan, and Bong. The TTX format allowed counties to collaborate utilizing open-source software platforms including Ushahidi, Sahana, QGIS, and KoBoCollect. PARTICIPANTS: Four hundred sixty-seven individuals (representing all 15 counties of Liberia) identified as key actors involved with emergency operations and disaster preparedness participated in the exercise. MAIN OUTCOME MEASURES: A qualitative survey with open-ended questions was administered to exercise participants to determine needed improvements in the disaster management system in Liberia. RESULTS: Key findings from the exercise and survey include the need for emergency management infrastructure to extend to the community level, establishment of a national disaster management agency and emergency operations center, customized local SOPs, ongoing surveillance, a disaster exercise program, and the need for effective data sharing and hazard maps. CONCLUSIONS: These regional exercises initiated the process of validating and refining Liberia's national and county-level SOPs. Liberia's participation in this exercise has provided a foundation for advancing its preparedness, response, and recovery capacities and could provide a template for other countries to use.
[Mh] Termos MeSH primário: Planejamento em Desastres/organização & administração
Surtos de Doenças/prevenção & controle
Auxiliares de Emergência/educação
Regionalização/organização & administração
[Mh] Termos MeSH secundário: Doença pelo Vírus Ebola/prevenção & controle
Seres Humanos
Libéria
Prevenção Primária/organização & administração
Avaliação de Programas e Projetos de Saúde
Prática de Saúde Pública
Treinamento por Simulação
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171103
[Lr] Data última revisão:
171103
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170820
[St] Status:MEDLINE


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[PMID]:28732038
[Au] Autor:Furuse Y; Fallah M; Oshitani H; Kituyi L; Mahmoud N; Musa E; Gasasira A; Nyenswah T; Dahn B; Bawo L
[Ad] Endereço:Frontier Research Institute for Interdisciplinary Sciences, Tohoku University, Sendai, Japan.
[Ti] Título:Analysis of patient data from laboratories during the Ebola virus disease outbreak in Liberia, April 2014 to March 2015.
[So] Source:PLoS Negl Trop Dis;11(7):e0005804, 2017 Jul.
[Is] ISSN:1935-2735
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:An outbreak of Ebola virus disease (EVD) in Liberia began in March 2014 and ended in January 2016. Epidemiological information on the EVD cases was collected and managed nationally; however, collection and management of the data were challenging at the time because surveillance and reporting systems malfunctioned during the outbreak. EVD diagnostic laboratories, however, were able to register basic demographic and clinical information of patients more systematically. Here we present data on 16,370 laboratory samples that were tested between April 4, 2014 and March 29, 2015. A total of 10,536 traceable individuals were identified, of whom 3,897 were confirmed cases (positive for Ebola virus RNA). There were significant differences in sex, age, and place of residence between confirmed and suspected cases that tested negative for Ebola virus RNA. Age (young children and the elderly) and place of residence (rural areas) were the risk factors for death due to the disease. The case fatality rate of confirmed cases decreased from 80% to 63% during the study period. These findings may help support future investigations and lead to a fuller understanding of the outbreak in Liberia.
[Mh] Termos MeSH primário: Surtos de Doenças/história
Ebolavirus/isolamento & purificação
Doença pelo Vírus Ebola/diagnóstico
Doença pelo Vírus Ebola/mortalidade
[Mh] Termos MeSH secundário: Adolescente
Adulto
Distribuição por Idade
Criança
Pré-Escolar
Demografia
Feminino
História do Século XXI
Seres Humanos
Laboratórios
Libéria/epidemiologia
Modelos Logísticos
Masculino
Programas de Rastreamento/métodos
Meia-Idade
Fatores de Risco
Distribuição por Sexo
Adulto Jovem
[Pt] Tipo de publicação:HISTORICAL ARTICLE; JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170813
[Lr] Data última revisão:
170813
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170722
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pntd.0005804


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[PMID]:28722621
[Au] Autor:McQuilkin PA; Udhayashankar K; Niescierenko M; Maranda L
[Ad] Endereço:Department of Pediatrics, University of Massachusetts Medical School, Worcester, Massachusetts.
[Ti] Título:Health-Care Access during the Ebola Virus Epidemic in Liberia.
[So] Source:Am J Trop Med Hyg;97(3):931-936, 2017 Sep.
[Is] ISSN:1476-1645
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The Ebola virus disease (EVD) epidemic, which began in West Africa in December 2013, claimed more than 11,000 lives, with more than 4,800 of these deaths occurring in Liberia. The epidemic had an additional effect of paralyzing the health-care systems in affected countries, which led to even greater mortality and morbidity. Little is known about the impact that the epidemic had on the provision of basic health care. During the period from March to May 2015, we undertook a nationwide, community-based survey to learn more about health-care access during the EVD epidemic in Liberia. A cluster sampling strategy was used to administer a structured in-person survey to heads of households located within the catchment areas surrounding all 21 government hospitals in Liberia. A total of 543 heads of household from all 15 counties in Liberia participated in the study; more than half (67%) of urban respondents and 46% of rural respondents stated that it was very difficult or impossible to access health care during the epidemic. In urban areas, only 20-30% of patients seeking care during the epidemic received care, and in rural areas, only 70-80% of those seeking care were able to access it. Patients requiring prenatal and obstetric care and emergency services had the most difficulty accessing care. The results of this survey support the observation that basic health care was extremely difficult to access during the EVD epidemic in Liberia. Our results underscore the critical need to support essential health-care services during humanitarian crises to minimize preventable morbidity and mortality.
[Mh] Termos MeSH primário: Assistência à Saúde
Epidemias
Doença pelo Vírus Ebola/epidemiologia
[Mh] Termos MeSH secundário: Adulto
Feminino
Seres Humanos
Libéria/epidemiologia
Masculino
Meia-Idade
Estudos Retrospectivos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171018
[Lr] Data última revisão:
171018
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170720
[St] Status:MEDLINE
[do] DOI:10.4269/ajtmh.16-0702


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[PMID]:28721175
[Au] Autor:Frimpong JA; Amo-Addae MP; Adewuyi PA; Hall CD; Park MM; Nagbe TK
[Ad] Endereço:Liberia Field Epidemiology Training Program, Monrovia, Liberia.
[Ti] Título:Conducting a surveillance problem analysis on poor feedback from Reference Laboratory, Liberia, February 2016.
[So] Source:Pan Afr Med J;27(Suppl 1):11, 2017.
[Is] ISSN:1937-8688
[Cp] País de publicação:Uganda
[La] Idioma:eng
[Ab] Resumo:The laboratory plays a major role in surveillance, including confirming the start and end of an outbreak. Knowing the causative agent for an outbreak informs the development of response strategies and management plans for a public health event. However, issues and challenges may arise that limit the effectiveness or efficiency of laboratories in surveillance. This case study applies a systematic approach to analyse gaps in laboratory surveillance, thereby improving the ability to mitigate these gaps. Although this case study concentrates on factors resulting in poor feedback from the laboratory, practise of this general approach to problem analysis will confer skills required in analysing most public health issues. This case study was developed based on a report submitted by the district surveillance officer in Grand Bassa County, Liberia, as a resident of the Liberian Frontline Field Epidemiology Training Program in 2016. This case study will serve as a training tool to reinforce lectures on surveillance problem analysis using the fishbone approach. It is designed for public health training in a classroom setting and can be completed within 2 hours 30 minutes.
[Mh] Termos MeSH primário: Epidemiologia/educação
Laboratórios/normas
Vigilância da População/métodos
Saúde Pública/educação
[Mh] Termos MeSH secundário: Surtos de Doenças
Métodos Epidemiológicos
Seres Humanos
Laboratórios/organização & administração
Libéria
Saúde Pública/métodos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170731
[Lr] Data última revisão:
170731
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170720
[St] Status:MEDLINE
[do] DOI:10.11604/pamj.supp.2017.27.1.12569



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