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[PMID]:29256429
[Au] Autor:Wyrosdick HM; Gerhold R; Su C; Mignucci-Giannoni AA; Bonde RK; Chapman A; Rivera-Pérez CI; Martinez J; Miller DL
[Ad] Endereço:University of Tennessee, Center for Wildlife Health, Department of Forestry, Wildlife, and Fisheries, Knoxville, TN 37996, USA.
[Ti] Título:Investigating seagrass in Toxoplasma gondii transmission in Florida (Trichechus manatus latirostris) and Antillean (T. m. manatus) manatees.
[So] Source:Dis Aquat Organ;127(1):65-69, 2017 Dec 19.
[Is] ISSN:0177-5103
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:Toxoplasma gondii is a feline protozoan reported to cause morbidity and mortality in manatees and other marine mammals. Given the herbivorous nature of manatees, ingestion of oocysts from contaminated water or seagrass is presumed to be their primary mode of infection. The objectives of this study were to investigate oocyst contamination of seagrass beds in Puerto Rico and determine the seroprevalence of T. gondii in Antillean (Trichechus manatus manatus) and Florida (T. m. latirostris) manatees. Sera or plasma from Antillean (n = 5) and Florida (n = 351) manatees were tested for T. gondii antibodies using the modified agglutination test. No T. gondii DNA was detected via PCR in seagrass samples (n = 33) collected from Puerto Rico. Seroprevalence was 0%, suggesting a lower prevalence of T. gondii in these manatee populations than previously reported. This was the first study to investigate the potential oocyst contamination of the manatee diet, and similar studies are important for understanding the epidemiology of T. gondii in herbivorous marine mammals.
[Mh] Termos MeSH primário: Plantas/parasitologia
Toxoplasma
Toxoplasmose Animal/transmissão
Trichechus manatus/parasitologia
[Mh] Termos MeSH secundário: Animais
Animais Selvagens
Florida/epidemiologia
Porto Rico/epidemiologia
Toxoplasmose Animal/sangue
Toxoplasmose Animal/parasitologia
Trichechus manatus/sangue
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180305
[Lr] Data última revisão:
180305
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171220
[St] Status:MEDLINE
[do] DOI:10.3354/dao03181


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[PMID]:29173742
[Au] Autor:Wei C; Eisenberg RE; Ramos-Olazagasti MA; Wall M; Chen C; Bird HR; Canino G; Duarte CS
[Ad] Endereço:Division of Child and Adolescent Psychiatry, Columbia University Medical Center/New York State Psychiatric Institute (CUMC/NYSPI), New York.
[Ti] Título:Developmental Psychopathology in a Racial/Ethnic Minority Group: Are Cultural Risks Relevant?
[So] Source:J Am Acad Child Adolesc Psychiatry;56(12):1081-1088.e1, 2017 Dec.
[Is] ISSN:1527-5418
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: The current study examined (a) the mediating role of parenting behaviors in the relationship between parental risks and youth antisocial behaviors (YASB), and (b) the role of youth cultural stress in a racial/ethnic minority group (i.e., Puerto Rican [PR] youth). METHOD: This longitudinal study consisted of 3 annual interviews of PR youth (N = 1,150; aged 10-14 years at wave 1) and their caretakers from the South Bronx (SB) in New York City and from San Juan, Puerto Rico. Parents reported on parental risks, parenting behaviors, and YASB. Youth also self-reported on YASB and youth cultural stress. A lagged structural equation model examined the relationship between these variables across 3 yearly waves, with youth cultural stress as a moderator of the association between effective parenting behaviors and YASB. RESULTS: Findings supported the positive influence of effective parenting on YASB, independently of past parental risks and past YASB: higher effective parenting significantly predicted lower YASB at the following wave. Parenting also accounted for (mediated) the association between the composite of parental risks and YASB. Youth cultural stress at wave 1 was cross-sectionally associated with higher YASB and moderated the prospective associations between effective parenting and YASB, such that for youth who perceived higher cultural stress, the positive effect of effective parenting on YASB was weakened compared to those with lower/average cultural stress. CONCLUSION: Among PR families, both parental and cultural risk factors influence YASB. Such findings should be considered when treating racial/ethnic minority youth for whom cultural factors may be a relevant influence on determining behaviors.
[Mh] Termos MeSH primário: Transtorno da Conduta/etnologia
Cultura
Hispano-Americanos/psicologia
Grupos Minoritários/psicologia
Poder Familiar/psicologia
Assunção de Riscos
Estresse Psicológico/etnologia
[Mh] Termos MeSH secundário: Adolescente
Criança
Transtorno da Conduta/psicologia
Feminino
Seres Humanos
Estudos Longitudinais
Masculino
Modelos Psicológicos
Modelos Estatísticos
Cidade de Nova Iorque
Estudos Prospectivos
Porto Rico/etnologia
Estresse Psicológico/psicologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180302
[Lr] Data última revisão:
180302
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171128
[St] Status:MEDLINE


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[PMID]:29470461
[Au] Autor:Va P; Luncheon C; Thompson-Paul AM; Fang J; Merritt R; Cogswell ME
[Ti] Título:Self-Reported Receipt of Advice and Action Taken To Reduce Dietary Sodium Among Adults With and Without Hypertension - Nine States and Puerto Rico, 2015.
[So] Source:MMWR Morb Mortal Wkly Rep;67(7):225-229, 2018 Feb 23.
[Is] ISSN:1545-861X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Hypertension is a major cardiovascular disease risk factor (1,2). Advice given by health professionals can result in lower sodium intake and lower blood pressure (3).The 2017 Hypertension Guideline released by the American College of Cardiology and the American Heart Association emphasizes nonpharmacologic approaches, including sodium reduction, as important components of hypertension prevention and treatment (4). Data from 50,576 participants in the sodium module of the 2015 Behavioral Risk Factor Surveillance System (BRFSS) in nine states and Puerto Rico were analyzed to determine the prevalence of reported sodium reduction advice and action among participants with and without self-reported hypertension. Among participants with self-reported hypertension, adjusted prevalence of receiving sodium reduction advice from a health professional was 41.9%, compared with 12.8% among participants without hypertension. Among those with hypertension, adjusted prevalence of reported action to reduce sodium intake was 80.9% among participants who received advice and 55.7% among those who did not receive advice. Among participants without hypertension, adjusted prevalence of taking action to reduce sodium intake was 72.7% among those who received advice and 46.9% among those who did not receive advice. The provision of advice on sodium reduction by health professionals is associated with respondent action to watch or reduce sodium intake. Fewer than half of patients with hypertension received this advice from their health professionals, a circumstance that represents a substantial missed opportunity to promote hypertension prevention and treatment.
[Mh] Termos MeSH primário: Aconselhamento Diretivo/estatística & dados numéricos
Comportamentos Relacionados com a Saúde
Hipertensão/epidemiologia
Sódio na Dieta/administração & dosagem
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Sistema de Vigilância de Fator de Risco Comportamental
Estudos Transversais
Feminino
Seres Humanos
Hipertensão/prevenção & controle
Masculino
Meia-Idade
Porto Rico/epidemiologia
Autorrelato
Estados Unidos/epidemiologia
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Sodium, Dietary)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180226
[Lr] Data última revisão:
180226
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180223
[St] Status:MEDLINE
[do] DOI:10.15585/mmwr.mm6707a5


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[PMID]:29370151
[Au] Autor:Delaney A; Mai C; Smoots A; Cragan J; Ellington S; Langlois P; Breidenbach R; Fornoff J; Dunn J; Yazdy M; Scotto-Rosato N; Sweatlock J; Fox D; Palacios J; Forestieri N; Leedom V; Smiley M; Nance A; Lake-Burger H; Romitti P; Fall C; Prado MV; Barton J; Bryan JM; Arias W; Brown SV; Kimura J; Mann S; Martin B; Orantes L; Taylor A; Nahabedian J; Akosa A; Song Z; Martin S; Ramlal R; Shapiro-Mendoza C; Isenburg J; Moore CA; Gilboa S; Honein MA
[Ti] Título:Population-Based Surveillance of Birth Defects Potentially Related to Zika Virus Infection - 15 States and U.S. Territories, 2016.
[So] Source:MMWR Morb Mortal Wkly Rep;67(3):91-96, 2018 Jan 26.
[Is] ISSN:1545-861X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Zika virus infection during pregnancy can cause serious birth defects, including microcephaly and brain abnormalities (1). Population-based birth defects surveillance systems are critical to monitor all infants and fetuses with birth defects potentially related to Zika virus infection, regardless of known exposure or laboratory evidence of Zika virus infection during pregnancy. CDC analyzed data from 15 U.S. jurisdictions conducting population-based surveillance for birth defects potentially related to Zika virus infection.* Jurisdictions were stratified into the following three groups: those with 1) documented local transmission of Zika virus during 2016; 2) one or more cases of confirmed, symptomatic, travel-associated Zika virus disease reported to CDC per 100,000 residents; and 3) less than one case of confirmed, symptomatic, travel-associated Zika virus disease reported to CDC per 100,000 residents. A total of 2,962 infants and fetuses (3.0 per 1,000 live births; 95% confidence interval [CI] = 2.9-3.2) (2) met the case definition. In areas with local transmission there was a non-statistically significant increase in total birth defects potentially related to Zika virus infection from 2.8 cases per 1,000 live births in the first half of 2016 to 3.0 cases in the second half (p = 0.10). However, when neural tube defects and other early brain malformations (NTDs) were excluded, the prevalence of birth defects strongly linked to congenital Zika virus infection increased significantly, from 2.0 cases per 1,000 live births in the first half of 2016 to 2.4 cases in the second half, an increase of 29 more cases than expected (p = 0.009). These findings underscore the importance of surveillance for birth defects potentially related to Zika virus infection and the need for continued monitoring in areas at risk for Zika.
[Mh] Termos MeSH primário: Anormalidades Congênitas/epidemiologia
Anormalidades Congênitas/virologia
Vigilância da População
Infecção pelo Zika virus/complicações
[Mh] Termos MeSH secundário: Feminino
Seres Humanos
Lactente
Recém-Nascido
Gravidez
Complicações Infecciosas na Gravidez/virologia
Prevalência
Porto Rico/epidemiologia
Estados Unidos/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180222
[Lr] Data última revisão:
180222
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180126
[St] Status:MEDLINE
[do] DOI:10.15585/mmwr.mm6703a2


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[PMID]:27773939
[Au] Autor:Wilson LE; Harlid S; Xu Z; Sandler DP; Taylor JA
[Ad] Endereço:Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, USA.
[Ti] Título:An epigenome-wide study of body mass index and DNA methylation in blood using participants from the Sister Study cohort.
[So] Source:Int J Obes (Lond);41(1):194-199, 2017 Jan.
[Is] ISSN:1476-5497
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND/OBJECTIVES: The relationship between obesity and chronic disease risk is well-established; the underlying biological mechanisms driving this risk increase may include obesity-related epigenetic modifications. To explore this hypothesis, we conducted a genome-wide analysis of DNA methylation and body mass index (BMI) using data from a subset of women in the Sister Study. SUBJECTS/METHODS: The Sister Study is a cohort of 50 884 US women who had a sister with breast cancer but were free of breast cancer themselves at enrollment. Study participants completed examinations which included measurements of height and weight, and provided blood samples. Blood DNA methylation data generated with the Illumina Infinium HumanMethylation27 BeadChip array covering 27,589 CpG sites was available for 871 women from a prior study of breast cancer and DNA methylation. To identify differentially methylated CpG sites associated with BMI, we analyzed this methylation data using robust linear regression with adjustment for age and case status. For those CpGs passing the false discovery rate significance level, we examined the association in a replication set comprised of a non-overlapping group of 187 women from the Sister Study who had DNA methylation data generated using the Infinium HumanMethylation450 BeadChip array. Analysis of this expanded 450 K array identified additional BMI-associated sites which were investigated with targeted pyrosequencing. RESULTS: Four CpG sites reached genome-wide significance (false discovery rate (FDR) q<0.05) in the discovery set and associations for all four were significant at strict Bonferroni correction in the replication set. An additional 23 sites passed FDR in the replication set and five were replicated by pyrosequencing in the discovery set. Several of the genes identified including ANGPT4, RORC, SOCS3, FSD2, XYLT1, ABCG1, STK39, ASB2 and CRHR2 have been linked to obesity and obesity-related chronic diseases. CONCLUSIONS: Our findings support the hypothesis that obesity-related epigenetic differences are detectable in blood and may be related to risk of chronic disease.
[Mh] Termos MeSH primário: Índice de Massa Corporal
Neoplasias da Mama/genética
Metilação de DNA
Epigênese Genética
Obesidade/genética
Irmãos
[Mh] Termos MeSH secundário: Neoplasias da Mama/epidemiologia
Estudos de Coortes
Ilhas de CpG/genética
Feminino
Estudo de Associação Genômica Ampla
Inquéritos Epidemiológicos
Seres Humanos
Meia-Idade
Obesidade/epidemiologia
Estudos Prospectivos
Porto Rico/epidemiologia
Estados Unidos/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180216
[Lr] Data última revisão:
180216
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161025
[St] Status:MEDLINE
[do] DOI:10.1038/ijo.2016.184


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[PMID]:27779466
[Au] Autor:Dirlikov E; Kniss K; Major C; Thomas D; Virgen CA; Mayshack M; Asher J; Mier-Y-Teran-Romero L; Salinas JL; Pastula DM; Sharp TM; Sejvar J; Johansson MA; Rivera-Garcia B
[Ti] Título:Guillain-Barré Syndrome and Healthcare Needs during Zika Virus Transmission, Puerto Rico, 2016.
[So] Source:Emerg Infect Dis;23(1):134-136, 2017 01.
[Is] ISSN:1080-6059
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:To assist with public health preparedness activities, we estimated the number of expected cases of Zika virus in Puerto Rico and associated healthcare needs. Estimated annual incidence is 3.2-5.1 times the baseline, and long-term care needs are predicted to be 3-5 times greater than in years with no Zika virus.
[Mh] Termos MeSH primário: Surtos de Doenças
Síndrome de Guillain-Barré/epidemiologia
Necessidades e Demandas de Serviços de Saúde/estatística & dados numéricos
Modelos Estatísticos
Infecção pelo Zika virus/epidemiologia
[Mh] Termos MeSH secundário: Previsões
Síndrome de Guillain-Barré/complicações
Síndrome de Guillain-Barré/terapia
Síndrome de Guillain-Barré/virologia
Seres Humanos
Incidência
Assistência de Longa Duração/estatística & dados numéricos
Método de Monte Carlo
Vigilância da População
Porto Rico/epidemiologia
Zika virus/patogenicidade
Zika virus/fisiologia
Infecção pelo Zika virus/complicações
Infecção pelo Zika virus/terapia
Infecção pelo Zika virus/virologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180209
[Lr] Data última revisão:
180209
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161026
[St] Status:MEDLINE
[do] DOI:10.3201/eid2301.161290


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[PMID]:29298320
[Au] Autor:Buczak AL; Baugher B; Moniz LJ; Bagley T; Babin SM; Guven E
[Ad] Endereço:Johns Hopkins University Applied Physics Laboratory, Laurel, Maryland, United States of America.
[Ti] Título:Ensemble method for dengue prediction.
[So] Source:PLoS One;13(1):e0189988, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: In the 2015 NOAA Dengue Challenge, participants made three dengue target predictions for two locations (Iquitos, Peru, and San Juan, Puerto Rico) during four dengue seasons: 1) peak height (i.e., maximum weekly number of cases during a transmission season; 2) peak week (i.e., week in which the maximum weekly number of cases occurred); and 3) total number of cases reported during a transmission season. A dengue transmission season is the 12-month period commencing with the location-specific, historical week with the lowest number of cases. At the beginning of the Dengue Challenge, participants were provided with the same input data for developing the models, with the prediction testing data provided at a later date. METHODS: Our approach used ensemble models created by combining three disparate types of component models: 1) two-dimensional Method of Analogues models incorporating both dengue and climate data; 2) additive seasonal Holt-Winters models with and without wavelet smoothing; and 3) simple historical models. Of the individual component models created, those with the best performance on the prior four years of data were incorporated into the ensemble models. There were separate ensembles for predicting each of the three targets at each of the two locations. PRINCIPAL FINDINGS: Our ensemble models scored higher for peak height and total dengue case counts reported in a transmission season for Iquitos than all other models submitted to the Dengue Challenge. However, the ensemble models did not do nearly as well when predicting the peak week. CONCLUSIONS: The Dengue Challenge organizers scored the dengue predictions of the Challenge participant groups. Our ensemble approach was the best in predicting the total number of dengue cases reported for transmission season and peak height for Iquitos, Peru.
[Mh] Termos MeSH primário: Dengue/epidemiologia
[Mh] Termos MeSH secundário: Seres Humanos
Modelos Teóricos
Peru/epidemiologia
Probabilidade
Porto Rico/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180129
[Lr] Data última revisão:
180129
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180104
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0189988


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[PMID]:29240728
[Au] Autor:Marynak K; Kenemer B; King BA; Tynan MA; MacNeil A; Reimels E
[Ad] Endereço:Office on Smoking and Health, National Center for Chronic Disease Prevention and Health Promotion, CDC.
[Ti] Título:State Laws Regarding Indoor Public Use, Retail Sales, and Prices of Electronic Cigarettes - U.S. States, Guam, Puerto Rico, and U.S. Virgin Islands, September 30, 2017.
[So] Source:MMWR Morb Mortal Wkly Rep;66(49):1341-1346, 2017 Dec 15.
[Is] ISSN:1545-861X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Electronic cigarettes (e-cigarettes) are the most frequently used tobacco product among U.S. youths, and past 30-day e-cigarette use is more prevalent among high school students than among adults (1,2). E-cigarettes typically deliver nicotine, and the U.S. Surgeon General has concluded that nicotine exposure during adolescence can cause addiction and can harm the developing adolescent brain (2). Through authority granted by the Family Smoking Prevention and Tobacco Control Act, the Food and Drug Administration (FDA) prohibits e-cigarette sales to minors, free samples, and vending machine sales, except in adult-only facilities (3). States, localities, territories, and tribes maintain broad authority to adopt additional or more stringent requirements regarding tobacco product use, sales, marketing, and other topics (2,4). To understand the current e-cigarette policy landscape in the United States, CDC assessed state and territorial laws that 1) prohibit e-cigarette use and conventional tobacco smoking indoors in restaurants, bars, and worksites; 2) require a retail license to sell e-cigarettes; 3) prohibit e-cigarette self-service displays (e.g., requirement that products be kept behind the counter or in a locked box); 4) establish 21 years as the minimum age of purchase for all tobacco products, including e-cigarettes (tobacco-21); and 5) apply an excise tax to e-cigarettes. As of September 30, 2017, eight states, the District of Columbia (DC), and Puerto Rico prohibited indoor e-cigarette use and smoking in indoor areas of restaurants, bars, and worksites; 16 states, DC, and the U.S. Virgin Islands required a retail license to sell e-cigarettes; 26 states prohibited e-cigarette self-service displays; five states, DC, and Guam had tobacco-21 laws; and eight states, DC, Puerto Rico, and the U.S. Virgin Islands taxed e-cigarettes. Sixteen states had none of the assessed laws. A comprehensive approach that combines state-level strategies to reduce youths' initiation of e-cigarettes and population exposure to e-cigarette aerosol, coupled with federal regulation, could help reduce health risks posed by e-cigarettes among youths (2,5).
[Mh] Termos MeSH primário: Poluição do Ar em Ambientes Fechados/legislação & jurisprudência
Comércio/legislação & jurisprudência
Sistemas Eletrônicos de Liberação de Nicotina
Vaping/legislação & jurisprudência
[Mh] Termos MeSH secundário: Sistemas Eletrônicos de Liberação de Nicotina/economia
Guam
Seres Humanos
Porto Rico
Estados Unidos
Ilhas Virgens Americanas
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1712
[Cu] Atualização por classe:180119
[Lr] Data última revisão:
180119
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171215
[St] Status:MEDLINE
[do] DOI:10.15585/mmwr.mm6649a1


  9 / 5386 MEDLINE  
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[PMID]:29190725
[Au] Autor:Ortiz AP; Ortiz-Ortiz KJ; Ríos M; Laborde J; Kulkarni A; Pillsbury M; Lauschke A; Monsanto HA; Marques-Goyco C
[Ad] Endereço:Cancer Control and Population Sciences Program, University of Puerto Rico Comprehensive Cancer Center, San Juan, Puerto Rico.
[Ti] Título:Modelling the effects of quadrivalent Human Papillomavirus (HPV) vaccination in Puerto Rico.
[So] Source:PLoS One;12(11):e0184540, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: No study has estimated the potential impact of Human Papillomavirus (HPV) vaccination in Puerto Rico, a population with considerable burden of HPV-related morbidities. We evaluated the health and economic impacts of implementing a vaccination strategy for females and males in Puerto Rico, with the quadrivalent HPV (HPV4) vaccine, under different vaccination scenarios. METHODS: We adapted a mathematical model which estimates the direct and indirect health benefits and costs of HPV4 vaccination in a dynamic population. The model compared three vaccination scenarios against screening only (no-vaccination) for three doses of HPV4 vaccine among individuals aged 11-15 years in Puerto Rico: 1) 34% for females and 13% for males (34%F/13%M), 2) 50% for females and 40% for males (50%F/40%M), and 3) 80% for female and 64% for male (80%F/64%M). Data specific to Puerto Rico was used. When not available, values from the United States were used. Input data consisted of demographic, behavioral, epidemiological, screening, and economic parameters. RESULTS: The model predicted decreases in: 1) HPV infection prevalence for females and males, 2) cervical intraepithelial neoplasia and cervical cancer incidence for females, 3) genital warts incidence for females and males, and 4) cervical cancer deaths among females, when various vaccination program scenarios were considered. In addition, when the vaccination percentage was increased in every scenario, the reduction was greater and began earlier. The analysis also evidenced an incremental cost effectiveness ratio (ICER) of $1,964 per quality-adjusted life year gained for the 80%F/64%M uptake scenario. CONCLUSIONS: HPV vaccine can prove its cost effectiveness and substantially reduce the burden and costs associated to various HPV-related conditions when targeted to the adequate population together with an organized HPV vaccination program.
[Mh] Termos MeSH primário: Modelos Teóricos
Vacinas contra Papillomavirus/imunologia
[Mh] Termos MeSH secundário: Adolescente
Alphapapillomavirus/classificação
Alphapapillomavirus/imunologia
Criança
Feminino
Seres Humanos
Masculino
Infecções por Papillomavirus/prevenção & controle
Infecções por Papillomavirus/virologia
Vacinas contra Papillomavirus/administração & dosagem
Porto Rico
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Papillomavirus Vaccines)
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171226
[Lr] Data última revisão:
171226
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171201
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0184540


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[PMID]:29193953
[Au] Autor:Dávila PJ; Pilar-Fernandez M; Ulloa-Padilla JP; Villegas VM; Lopez V; Rivera L; Santos CA; Santiago-Cabán LA
[Ti] Título:Clinical profile, bacterial isolates, and antibiotic resistance of corneal ulcers in Puerto Rico.
[So] Source:Bol Asoc Med P R;108(1):45-50, 2016.
[Is] ISSN:0004-4849
[Cp] País de publicação:Puerto Rico
[La] Idioma:eng
[Mh] Termos MeSH primário: Antibacterianos/farmacologia
Úlcera da Córnea/tratamento farmacológico
Infecções Oculares Bacterianas/tratamento farmacológico
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Idoso de 80 Anos ou mais
Bactérias/efeitos dos fármacos
Bactérias/isolamento & purificação
Criança
Pré-Escolar
Úlcera da Córnea/microbiologia
Farmacorresistência Bacteriana
Infecções Oculares Bacterianas/microbiologia
Feminino
Seres Humanos
Lactente
Masculino
Meia-Idade
Porto Rico
Estudos Retrospectivos
Fatores de Risco
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Bacterial Agents)
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171214
[Lr] Data última revisão:
171214
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171202
[St] Status:MEDLINE



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