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[PMID]:29182246
[Au] Autor:Walchok JG; Lutz ME; Pirrallo RG
[Ti] Título:Prehospital Antibiotics. Greenville, S.C. brings definitive sepsis care into the ambulance.
[So] Source:JEMS;41(9):36-9, 2016 09.
[Is] ISSN:0197-2510
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Antibacterianos/uso terapêutico
Serviços Médicos de Emergência/organização & administração
Sepse/diagnóstico
Sepse/tratamento farmacológico
[Mh] Termos MeSH secundário: Ambulâncias
Seres Humanos
South Carolina
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Bacterial Agents)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180108
[Lr] Data última revisão:
180108
[Sb] Subgrupo de revista:H
[Da] Data de entrada para processamento:171129
[St] Status:MEDLINE


  2 / 5509 MEDLINE  
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[PMID]:29240325
[Ti] Título:Tort Law--Expert Testimony in Asbestos Litigation--District of South Carolina Holds the Every Exposure Theory Insufficient to Demonstrate Specific Causation Even If Legal Conclusions are Scientifically Sound.--Haskins v. 3m Co., Nos. 2:15-cv-02086, 3:15-cv-02123, 2017 WL 3118017 (D.S.C. July 21, 2017).
[So] Source:Harv Law Rev;131(2):658-65, 2017 Dec.
[Is] ISSN:0017-811X
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Asbestose/etiologia
Causalidade
Prova Pericial/legislação & jurisprudência
Mesotelioma/etiologia
[Mh] Termos MeSH secundário: Seres Humanos
Ciência
South Carolina
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180105
[Lr] Data última revisão:
180105
[Sb] Subgrupo de revista:T
[Da] Data de entrada para processamento:171215
[St] Status:MEDLINE


  3 / 5509 MEDLINE  
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[PMID]:29191313
[Au] Autor:Tipton JJ; Guillette LJ; Lovelace S; Parrott BB; Rainwater TR; Reiner JL
[Ad] Endereço:College of Charleston, Charleston, SC 29724, USA.
[Ti] Título:Analysis of PFAAs in American alligators part 2: Potential dietary exposure of South Carolina hunters from recreationally harvested alligator meat.
[So] Source:J Environ Sci (China);61:31-38, 2017 Nov.
[Is] ISSN:1001-0742
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Exposure to perfluorinated alkyl acids (PFAAs) has been linked to many harmful health effects including reproductive disorders, developmental delays, and altered liver and kidney function. Most human exposure to environmental contaminants, including PFAAs, occurs through consumption of contaminated food or drinking water. This study uses PFAA data from meat samples collected from recreationally harvested American alligators (Alligator mississippiensis) in South Carolina to assess potential dietary exposure of hunters and their families to PFAAs. Consumption patterns were investigated using intercept surveys of 23 hunters at a wild game meat processor. An exposure scenario using the average consumption frequency, portion size, and median perfluorooctane sulfonic acid (PFOS) concentration in alligator meat from all hunt units found the daily dietary exposure to be 2.11ng/kg body weight per day for an adult human. Dietary PFOS exposure scenarios based on location of harvest suggested the highest daily exposure occurs with alligator meat from the Middle Coastal hunt unit in South Carolina. Although no samples were found to exceed the recommended threshold for no consumption of PFOS found in Minnesota state guidelines, exposure to a mixture of PFAAs found in alligator meat and site-specific exposures based on harvest location should be considered in determining an appropriate guideline for vulnerable populations potentially exposed to PFAAs through consumption of wild alligator meat.
[Mh] Termos MeSH primário: Jacarés e Crocodilos/metabolismo
Exposição Dietética/estatística & dados numéricos
Poluentes Ambientais/metabolismo
Fluorcarbonetos/metabolismo
Carne/análise
[Mh] Termos MeSH secundário: Ácidos Alcanossulfônicos/metabolismo
Animais
Monitoramento Ambiental
Contaminação de Alimentos/análise
Seres Humanos
South Carolina
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Alkanesulfonic Acids); 0 (Environmental Pollutants); 0 (Fluorocarbons); 9H2MAI21CL (perfluorooctane sulfonic acid)
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171207
[Lr] Data última revisão:
171207
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171202
[St] Status:MEDLINE


  4 / 5509 MEDLINE  
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[PMID]:29191311
[Au] Autor:Tipton JJ; Guillette LJ; Lovelace S; Parrott BB; Rainwater TR; Reiner JL
[Ad] Endereço:College of Charleston, Charleston, SC 29424, USA.
[Ti] Título:Analysis of PFAAs in American alligators part 1: Concentrations in alligators harvested for consumption during South Carolina public hunts.
[So] Source:J Environ Sci (China);61:24-30, 2017 Nov.
[Is] ISSN:1001-0742
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Environmental contamination resulting from the production or release of harmful chemicals can lead to negative consequences for wildlife and human health. Perfluorinated alkyl acids (PFAAs) were historically produced as protective coatings for many household items and currently persist in the environment, wildlife, and humans. PFAAs have been linked to immune suppression, endocrine disruption, and developmental toxicity in wildlife and laboratory studies. This study examines the American alligator, Alligator mississippiensis, as an important indicator of ecosystem contamination and a potential pathway for PFAA exposure in humans. Alligator meat harvested in the 2015 South Carolina (SC) public hunt season and prepared for human consumption was collected and analyzed for PFAAs to determine meat concentrations and relationships with animal body size (total length), sex, and location of harvest. Of the 15 PFAAs analyzed, perfluorooctane sulfonate (PFOS) was found in all alligator meat samples and at the highest concentrations (median 6.73ng/g). No relationship was found between PFAA concentrations and total length or sex. Concentrations of one or all compounds varied significantly across sampling locations, with alligators harvested in the Middle Coastal hunt unit having the highest PFOS concentrations (median 16.0ng/g; p=0.0001). Alligators harvested specifically from Berkley County, SC (located in the Middle Coastal hunt unit) had the highest PFOS concentrations and the greatest number of PFAAs detected (p<0.0001). The site-specific nature of PFAA concentrations in alligator meat observed in this study suggests a source of PFAA contamination in Berkley County, SC.
[Mh] Termos MeSH primário: Jacarés e Crocodilos/metabolismo
Monitoramento Ambiental
Poluentes Ambientais/metabolismo
Fluorcarbonetos/metabolismo
[Mh] Termos MeSH secundário: Ácidos Alcanossulfônicos/metabolismo
Animais
Disruptores Endócrinos/metabolismo
South Carolina
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Alkanesulfonic Acids); 0 (Endocrine Disruptors); 0 (Environmental Pollutants); 0 (Fluorocarbons); 9H2MAI21CL (perfluorooctane sulfonic acid)
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171207
[Lr] Data última revisão:
171207
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171202
[St] Status:MEDLINE


  5 / 5509 MEDLINE  
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[PMID]:27778313
[Au] Autor:Spigler RB; Theodorou K; Chang SM
[Ad] Endereço:Department of Biology, Temple University, 1900 N. 12th Street, Philadelphia, Pennsylvania, 19122.
[Ti] Título:Inbreeding depression and drift load in small populations at demographic disequilibrium.
[So] Source:Evolution;71(1):81-94, 2017 01.
[Is] ISSN:1558-5646
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Inbreeding depression is a major driver of mating system evolution and has critical implications for population viability. Theoretical and empirical attention has been paid to predicting how inbreeding depression varies with population size. Lower inbreeding depression is predicted in small populations at equilibrium, primarily due to higher inbreeding rates facilitating purging and/or fixation of deleterious alleles (drift load), but predictions at demographic and genetic disequilibrium are less clear. In this study, we experimentally evaluate how lifetime inbreeding depression and drift load, estimated by heterosis, vary with census (N ) and effective (estimated as genetic diversity, H ) population size across six populations of the biennial Sabatia angularis as well as present novel models of inbreeding depression and heterosis under varying demographic scenarios at disequilibrium (fragmentation, bottlenecks, disturbances). Our experimental study reveals high average inbreeding depression and heterosis across populations. Across our small sample, heterosis declined with H , as predicted, whereas inbreeding depression did not vary with H and actually decreased with N . Our theoretical results demonstrate that inbreeding depression and heterosis levels can vary widely across populations at disequilibrium despite similar H and highlight that joint demographic and genetic dynamics are key to predicting patterns of genetic load in nonequilibrium systems.
[Mh] Termos MeSH primário: Genética Populacional
Gentianaceae/genética
Vigor Híbrido
Depressão por Endogamia
[Mh] Termos MeSH secundário: Carga Genética
Variação Genética
North Carolina
Densidade Demográfica
South Carolina
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, U.S. GOV'T, NON-P.H.S.; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1709
[Cu] Atualização por classe:171130
[Lr] Data última revisão:
171130
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161026
[St] Status:MEDLINE
[do] DOI:10.1111/evo.13103


  6 / 5509 MEDLINE  
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[PMID]:28972427
[Au] Autor:Shi L; Feng C; Griffin S; Williams JE; Crandall LA; Truong K
[Ad] Endereço:1 Clemson University, SC, USA.
[Ti] Título:Does Awareness of the Affordable Care Act Reduce Adverse Selection? A Study of the Long-term Uninsured in South Carolina.
[So] Source:Inquiry;54:46958017727103, 2017 Jan 01.
[Is] ISSN:1945-7243
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Adverse selection predicts that individuals with lower health status would be more likely to sign up for health insurance. This hypothesis was tested among the long-term uninsured population in South Carolina (SC). This study used data from an in-person survey conducted from May 2014 to January 2015. Interviews were held with the long-term uninsured individuals at multiple sites throughout the state, using a multistage sampling method. SC residents aged 18 to 64 years who had had no health insurance for at least 24 consecutive months were eligible for the survey. The dependent variable is the participants' attempt to obtain insurance coverage. Key independent variables are self-reported health status, hospitalization in the past year, use of emergency department in the past year, and presence of serious long-standing health problems. The analysis is stratified by the awareness of the Affordable Care Act (ACA)'s individual mandate while controlling for age, gender, race/ethnicity, and household income. Participants' self-reported health status was not significantly associated with the attempt to sign up for health insurance in both groups (those aware and those unaware of the individual mandate). Being hospitalized in the previous year was significantly associated with their attempt to sign up for insurance in both groups. Participants with serious long-term health problems were more likely to have attempted to sign up for insurance among those who were not aware of the ACA. However, this association was statistically insignificant among those who had heard of ACA. Sicker people were more likely to attempt to sign up for insurance. However, being aware of the ACA's individual mandate seemed to play a role in reducing adverse selection.
[Mh] Termos MeSH primário: Cobertura do Seguro/estatística & dados numéricos
Seguro Saúde/estatística & dados numéricos
Pessoas sem Cobertura de Seguro de Saúde/estatística & dados numéricos
Patient Protection and Affordable Care Act/legislação & jurisprudência
[Mh] Termos MeSH secundário: Adulto
Doença Crônica
Grupos Étnicos/estatística & dados numéricos
Feminino
Nível de Saúde
Hospitalização/estatística & dados numéricos
Seres Humanos
Masculino
Meia-Idade
South Carolina
Inquéritos e Questionários
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171016
[Lr] Data última revisão:
171016
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171004
[St] Status:MEDLINE
[do] DOI:10.1177/0046958017727103


  7 / 5509 MEDLINE  
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[PMID]:28881956
[Au] Autor:Reay-Jones FPF
[Ad] Endereço:Department of Plant and Environmental Sciences, Pee Dee Research and Education Center, Clemson University, 2200 Pocket Rd., Florence, SC 29506-9727.
[Ti] Título:Geostatistical Characterization of Cereal Leaf Beetle (Coleoptera: Chrysomelidae) Distributions in Wheat.
[So] Source:Environ Entomol;46(4):931-938, 2017 08 01.
[Is] ISSN:1938-2936
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:A 3-yr study was conducted in wheat, Triticum aestivum L., in South Carolina to characterize the spatial distribution of Oulema melanopus (L.) adults, eggs, and larvae using semivariograms, which provides a measure of spatial dependence among sampling data. Moran's I coefficients for peak densities of each life stage indicated significant positive autocorrelation for seven (two for eggs, one for larvae, and four for adults) of the 16 datasets. Aggregation was detected in 13 of these 16 datasets when analyzed by semivariogram modeling, with spherical, Gaussian, and exponential models best fitting for eight, four, and one dataset, respectively, and with models for two datasets having only one parameter (nugget) significantly different from zero. The nugget-to-sill ratios ranged from 0.043 to 0.774, and indicated strong spatial dependence in six models (three for adults, two for eggs, and one for larvae), moderate spatial dependence in six models (three for adults and six for eggs), and weak spatial dependence in one model (adults). Range values varied from 39.1 m to 234.1 m, with an average of 120.1 ± 14.0 m. Average range values were 104.9, 135.2, and 161.2 m for adults, eggs, and larvae, respectively. Because the majority of semivariogram models in our study indicated aggregated distributions, spatial sampling will provide more information than nonspatial random sampling. Developing our understanding of spatial dependence of crop pests is needed to optimize sampling plans and can provide a basis for exploring site-specific management tactics.
[Mh] Termos MeSH primário: Distribuição Animal
Coleópteros/fisiologia
Triticum
[Mh] Termos MeSH secundário: Animais
Coleópteros/crescimento & desenvolvimento
Larva/crescimento & desenvolvimento
Larva/fisiologia
Modelos Estatísticos
Óvulo/crescimento & desenvolvimento
Óvulo/fisiologia
South Carolina
Triticum/crescimento & desenvolvimento
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, U.S. GOV'T, NON-P.H.S.
[Em] Mês de entrada:1709
[Cu] Atualização por classe:171126
[Lr] Data última revisão:
171126
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170909
[St] Status:MEDLINE
[do] DOI:10.1093/ee/nvx122


  8 / 5509 MEDLINE  
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[PMID]:28832922
[Au] Autor:Stojanowski CM; Paul KS; Seidel AC; Duncan WN; Guatelli-Steinberg D
[Ad] Endereço:Center for Bioarchaeological Research, School of Human Evolution and Social Change, Arizona State University, Tempe, Arizona, 85287.
[Ti] Título:Heritability and genetic integration of tooth size in the South Carolina Gullah.
[So] Source:Am J Phys Anthropol;164(3):505-521, 2017 Nov.
[Is] ISSN:1096-8644
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVES: This article provides estimates of narrow-sense heritability and genetic pleiotropy for mesiodistal tooth dimensions for a sample of 20th century African American individuals. Results inform biological distance analysis and offer insights into patterns of integration in the human dentition. MATERIALS AND METHODS: Maximum mesiodistal crown dimensions were measured using Hillson-FitzGerald calipers on 469 stone dental casts from the Menegaz-Bock Collection. Narrow-sense heritability estimates and genetic and phenotypic correlations were estimated using SOLAR 8.1.1 with covariate screening for age, sex, age*sex interaction, and birth year. RESULTS: Heritability estimates were moderate (∼0.10 - 0.90; h mean = 0.51) for most measured variables with sex as the only significant covariate. Patterns of genetic correlation indicate strong integration across tooth classes, except molars. Comparison of these results to previously published work suggests lower overall heritability relative to other human populations and much stronger genetic integration across tooth classes than obtained from nonhuman primate genetic pleiotropy estimates. CONCLUSIONS: These results suggest that the high heritabilities previously published may reflect overestimates inherent in previous study designs; as such the standard estimate of 0.55 used in biodistance analyses may not be appropriate. For the Gullah, isolation and endogamy coupled with elevated levels of physiological and economic stress may suppress narrow-sense heritability estimates. Pleiotropy analyses suggest a more highly integrated dentition in humans than in other mammals.
[Mh] Termos MeSH primário: Afroamericanos/genética
Grupos Étnicos/genética
Tamanho do Órgão/genética
Característica Quantitativa Herdável
Dente/anatomia & histologia
[Mh] Termos MeSH secundário: Antropologia Física
Dentição Permanente
Feminino
Seres Humanos
Masculino
Odontometria
South Carolina
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171030
[Lr] Data última revisão:
171030
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170824
[St] Status:MEDLINE
[do] DOI:10.1002/ajpa.23290


  9 / 5509 MEDLINE  
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[PMID]:28755732
[Au] Autor:Austin A; Jogani SN; Brasher PB; Argula RG; Huggins JT; Chopra A
[Ad] Endereço:Department of Medicine, Albany Medical College, Albany, New York. Electronic address: Austina4@mail.amc.edu.
[Ti] Título:The Urinothorax: A Comprehensive Review With Case Series.
[So] Source:Am J Med Sci;354(1):44-53, 2017 Jul.
[Is] ISSN:1538-2990
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Urinothorax is an uncommon thoracic complication of genitourinary (GU) tract disease, which is most frequently caused by obstructive uropathy, but may also occur as a result of iatrogenic or traumatic GU injury. It is underrecognized because of a perceived notion as to the rarity of the diagnosis and the absence of established diagnostic criteria. Urinothorax is typically described as a paucicellular, transudative pleural effusion with a pleural fluid/serum creatinine ratio >1.0. It is the only transudate associated with pleural fluid acidosis (pH < 7.40). When the pleural fluid analysis demonstrates features of a transudate, pH <7.40 and a pleural fluid/serum creatinine ratio >1.0, a confident clinical diagnosis of urinothorax can be established. A technetium 99m renal scan can be considered a confirmatory test in patients who lack the typical pleural fluid analysis features or fail to demonstrate evidence of obstructive uropathy that can be identified via conventional radiographic modalities. Management of a urinothorax requires a multidisciplinary approach with an emphasis on the correction of the underlying GU tract pathology, and once corrected, this often leads to a rapid resolution of the pleural effusion.
[Mh] Termos MeSH primário: Hidronefrose/complicações
Derrame Pleural/complicações
Urinoma
[Mh] Termos MeSH secundário: Idoso
Idoso de 80 Anos ou mais
Exsudatos e Transudatos/diagnóstico por imagem
Feminino
Seres Humanos
Hidronefrose/cirurgia
Rim/diagnóstico por imagem
Masculino
Meia-Idade
New York
Derrame Pleural/cirurgia
South Carolina
Urinoma/diagnóstico
Urinoma/etiologia
Urinoma/cirurgia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170824
[Lr] Data última revisão:
170824
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170731
[St] Status:MEDLINE


  10 / 5509 MEDLINE  
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[PMID]:28679018
[Au] Autor:SanGiovanni C; McElligott J; Morella K; Basco W
[Ad] Endereço:From the Departments of Pediatrics and Public Health, Medical University of South Carolina, Charleston.
[Ti] Título:Underdiagnosis and Lower Rates of Office Visits for Overweight/Obese Pediatric Patients in Rural Compared with Urban Areas.
[So] Source:South Med J;110(7):480-485, 2017 Jul.
[Is] ISSN:1541-8243
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVES: This study compared the number of children enrolled in Medicaid in rural and urban areas of South Carolina with an overweight/obesity diagnosis and the mean rates of office visits with overweight/obesity diagnosed. METHODS: Medicaid claims data from 2012 for children in three South Carolina counties, categorized as urban, rural high resource, and rural low resource, were used to identify those who had been diagnosed as being overweight/obese during any encounter. Logistic and Poisson regressions were performed to predict whether overweight/obese children in each county would receive an overweight/obesity visit diagnosis and to calculate the mean rate of total office visits with an overweight/obesity diagnosis in each county. RESULTS: A total of 1233 children enrolled in Medicaid were diagnosed as being overweight/obese at any encounter in the designated counties. Well visits with overweight/obesity diagnosed varied significantly, with 42.6%, 28%, and 11% in urban, rural high-resource counties, and rural low-resource counties, respectively ( < 0.01). In the logistic regression rural high-resource children (adjusted odds ratio 0.58, 95% confidence interval 0.38-0.88) and rural low-resource children (adjusted odds ratio 0.16, 95% confidence interval 0.09-0.28) were less likely than urban children to be diagnosed as being overweight/obese at a well visit. All of the children had a low number of total office visits with overweight/obesity diagnosed. When comparing the counties, urban children (1.22 visits per year) had more visits than rural low-resource children (0.75 visits per year, < 0.01) and rural high-resource children (0.89 visits per year, < 0.01). CONCLUSIONS: Overweight/obesity is underdiagnosed in rural children enrolled in Medicaid in South Carolina, which affects the number of children who receive help to manage their weight. Interventions to overcome barriers of diagnosis and management are necessary to address childhood obesity properly.
[Mh] Termos MeSH primário: Erros de Diagnóstico/estatística & dados numéricos
Visita a Consultório Médico/utilização
Sobrepeso/diagnóstico
Obesidade Pediátrica/diagnóstico
População Rural/estatística & dados numéricos
População Urbana/estatística & dados numéricos
[Mh] Termos MeSH secundário: Adolescente
Criança
Pré-Escolar
Feminino
Recursos em Saúde/estatística & dados numéricos
Seres Humanos
Masculino
Medicaid
Sobrepeso/epidemiologia
Obesidade Pediátrica/epidemiologia
South Carolina
Estados Unidos
Revisão da Utilização de Recursos de Saúde
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170822
[Lr] Data última revisão:
170822
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170706
[St] Status:MEDLINE
[do] DOI:10.14423/SMJ.0000000000000672



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