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[PMID]:29446881
[Au] Autor:Clémençon R
[Ad] Endereço:University of California, Santa Barbara, California, USA.
[Ti] Título:"Zweckoptimismus" and the Paris process will not save the world from climate catastrophe.
[So] Source:Integr Environ Assess Manag;14(2):198-201, 2018 Mar.
[Is] ISSN:1551-3793
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Politicians, government officials, business representatives, and nongovernmental climate activists all in various ways emphasize what they see as progress being made in the aftermath of the Paris Agreement, even if they continue to warn of the dire consequences of business as usual. Indeed, there is no lack of encouraging private and public sector initiatives on climate change. Some macro trends seem to be moving in the right direction, as well. But, closer scrutiny shows that these positive trends are still far from adding up to the necessary fundamental shift in the global energy economy. Furthermore, the public may greatly overestimate the advancement of renewable solar and wind energy technology, which contributes to a false sense of progress and lessens political urgency. Without determined and reinvigorated political leadership from the European Union (EU), there is little hope that necessary emission reduction goals to stay below 2 °C above preindustrial levels can be met. The EU has driven international climate policy from the beginning of climate negotiations, and there is unfortunately no other source of leadership in sight. It will require difficult political decisions to be taken sooner rather than later to force a much quicker domestic energy transition and to raise financing to help developing countries with their own energy transition and adaptation to a rapidly warming world. Integr Environ Assess Manag 2018;14:198-201. © 2018 SETAC.
[Mh] Termos MeSH primário: Poluição do Ar/prevenção & controle
Mudança Climática
Política Ambiental
Gases de Efeito Estufa/análise
Cooperação Internacional
[Mh] Termos MeSH secundário: Poluição do Ar/estatística & dados numéricos
União Europeia
Efeito Estufa
Paris
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Greenhouse Gases)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180216
[St] Status:MEDLINE
[do] DOI:10.1002/ieam.2015


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[PMID]:28749333
[Au] Autor:Bassi C; Taha MK; Merle C; Hong E; Lévy-Bruhl D; Barret AS; Mounchetrou Njoya I
[Ad] Endereço:Santé publique France, French National Public Health Agency, Regional Unit (Cire) Ile-de-France, Paris, France.
[Ti] Título:A cluster of invasive meningococcal disease (IMD) caused by Neisseria meningitidis serogroup W among university students, France, February to May 2017.
[So] Source:Euro Surveill;22(28), 2017 Jul 13.
[Is] ISSN:1560-7917
[Cp] País de publicação:Sweden
[La] Idioma:eng
[Ab] Resumo:Between February and May 2017, two cases of invasive meningococcal disease caused by a new, rapidly expanding serogroup W meningococci variant were reported among students of an international university in Paris. Bacteriological investigations showed that isolates shared identical genotypic formula (W:P1.5,2:F1-1:cc11) and belonged to the South American/UK lineage. A vaccination campaign was organised that aimed at preventing new cases linked to potential persistence of the circulation of the bacteria in the students.
[Mh] Termos MeSH primário: Infecções Meningocócicas/diagnóstico
Neisseria meningitidis Sorogrupo W-135/isolamento & purificação
[Mh] Termos MeSH secundário: Busca de Comunicante
Febre/etiologia
Genótipo
Seres Humanos
Masculino
Infecções Meningocócicas/sangue
Infecções Meningocócicas/microbiologia
Tipagem Molecular
Neisseria meningitidis Sorogrupo W-135/genética
Paris
Sorogrupo
Estudantes
Sequenciamento Completo do Genoma
Adulto Jovem
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180306
[Lr] Data última revisão:
180306
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170728
[St] Status:MEDLINE


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[PMID]:27778092
[Au] Autor:Dossier C; Lapidus N; Bayer F; Sellier-Leclerc AL; Boyer O; de Pontual L; May A; Nathanson S; Orzechowski C; Simon T; Carrat F; Deschênes G
[Ad] Endereço:Service de Néphrologie Pédiatrique, Hôpital Robert-Debré, APHP, Paris, France. claire.dossier@aphp.fr.
[Ti] Título:Epidemiology of idiopathic nephrotic syndrome in children: endemic or epidemic?
[So] Source:Pediatr Nephrol;31(12):2299-2308, 2016 Dec.
[Is] ISSN:1432-198X
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The etiology of idiopathic nephrotic syndrome (INS) remains partially unknown. Viral infections have been reported to be associated with INS onset and relapse. The aim of this study was to describe the epidemiology of a population-based cohort of children with INS and propose a spatiotemporal analysis. METHODS: All children aged 6 months to 15 years with INS onset between December 2007 and May 2010 and living in the Paris area were included in a prospective multicenter study. Demographic and clinical features at diagnosis and 2 years were collected. RESULTS: INS was diagnosed in 188 children, 93 % of whom were steroid sensitive. Annual incidence was 3.35/100,000 children. Standardized incidence ratio (SIR) was higher in one of the eight counties: Seine-Saint-Denis, with SIR 1.43 [95 % confidence interval (CI) 1.02-1.95]. A spatial cluster was further identified with higher SIR 1.36 (95 % CI 1.09-1.67). Temporal analysis within this overincidence area showed seasonal variation, with a peak during the winter period (p <0.01). In addition, partition of the Paris area into quintiles of the population showed that the average delay of occurrence, with regard to the first study case, followed a longitudinal progression (p <0.0001). CONCLUSION: The clustering of cases, the seasonal variation within this particular area, and the progression over the Paris area altogether suggest that INS may occur on an epidemic mode.
[Mh] Termos MeSH primário: Síndrome Nefrótica/epidemiologia
[Mh] Termos MeSH secundário: Adolescente
Fatores Etários
Criança
Pré-Escolar
Análise por Conglomerados
Estudos de Coortes
Doenças Endêmicas
Epidemias
Feminino
Seres Humanos
Incidência
Lactente
Masculino
Síndrome Nefrótica/tratamento farmacológico
Síndrome Nefrótica/virologia
Paris/epidemiologia
Estudos Prospectivos
Estações do Ano
Fatores Socioeconômicos
Esteroides/uso terapêutico
[Pt] Tipo de publicação:JOURNAL ARTICLE; MULTICENTER STUDY
[Nm] Nome de substância:
0 (Steroids)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180226
[Lr] Data última revisão:
180226
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161026
[St] Status:MEDLINE


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[PMID]:29351341
[Au] Autor:Bibault JE; Zapletal E; Rance B; Giraud P; Burgun A
[Ad] Endereço:Radiation Oncology Department, Georges Pompidou European Hospital, Assistance Publique - Hôpitaux de Paris (AP-HP), Paris Descartes University, Paris Sorbonne Cité, Paris, France.
[Ti] Título:Labeling for Big Data in radiation oncology: The Radiation Oncology Structures ontology.
[So] Source:PLoS One;13(1):e0191263, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:PURPOSE: Leveraging Electronic Health Records (EHR) and Oncology Information Systems (OIS) has great potential to generate hypotheses for cancer treatment, since they directly provide medical data on a large scale. In order to gather a significant amount of patients with a high level of clinical details, multicenter studies are necessary. A challenge in creating high quality Big Data studies involving several treatment centers is the lack of semantic interoperability between data sources. We present the ontology we developed to address this issue. METHODS: Radiation Oncology anatomical and target volumes were categorized in anatomical and treatment planning classes. International delineation guidelines specific to radiation oncology were used for lymph nodes areas and target volumes. Hierarchical classes were created to generate The Radiation Oncology Structures (ROS) Ontology. The ROS was then applied to the data from our institution. RESULTS: Four hundred and seventeen classes were created with a maximum of 14 children classes (average = 5). The ontology was then converted into a Web Ontology Language (.owl) format and made available online on Bioportal and GitHub under an Apache 2.0 License. We extracted all structures delineated in our department since the opening in 2001. 20,758 structures were exported from our "record-and-verify" system, demonstrating a significant heterogeneity within a single center. All structures were matched to the ROS ontology before integration into our clinical data warehouse (CDW). CONCLUSION: In this study we describe a new ontology, specific to radiation oncology, that reports all anatomical and treatment planning structures that can be delineated. This ontology will be used to integrate dosimetric data in the Assistance Publique-Hôpitaux de Paris CDW that stores data from 6.5 million patients (as of February 2017).
[Mh] Termos MeSH primário: Ontologias Biológicas/estatística & dados numéricos
Radioterapia (Especialidade)/estatística & dados numéricos
[Mh] Termos MeSH secundário: Registros Eletrônicos de Saúde
Seres Humanos
Armazenamento e Recuperação da Informação
Sistemas de Informação
Modelos Anatômicos
Neoplasias/radioterapia
Paris
Planejamento da Radioterapia Assistida por Computador/estatística & dados numéricos
Software
Integração de Sistemas
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180221
[Lr] Data última revisão:
180221
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180120
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0191263


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[PMID]:29283539
[Au] Autor:Mouthon JM
[Ti] Título:[In process]
[Ti] Título:Médicins Savoyard qui ont soutenu leur these de doctorat en France au XIX siècle, à Paris principalement..
[So] Source:Vesalius;22(2):37-43, 2016 Dec.
[Is] ISSN:1373-4857
[Cp] País de publicação:Belgium
[La] Idioma:fre
[Ab] Resumo:Savoy, annexed by the French Revolution from 1792 to 1815, became again Sardinian within the kingdom of Piedmont-Sardinia until 1860, the year of annexation to France. These changes have not prevented many students from Savoy to come to France for their medical studies, mostly in Paris. While disorganized by the Revolution, medical training and education systems were put in order as of 1803. The Theses of 142 Savoy students (found largely thanks to foreign students in Paris file prepared by Pierre Moulinier) could be consulted in the archives of the Bibliothèque interuniversitaire de santé de Paris. Accordingly, were studied the geographical origin of candidates, thesis topics, age of the students, the philanthropic Savoisienne society of Paris, the Savoy students who exercised in Paris, the students who were former militaries and the doctors who had a local or national political mandate. A similar study at the Faculty of Turin would allow to better understand the migratory flows of these students.
[Mh] Termos MeSH primário: Dissertações Acadêmicas como Assunto/história
Médicos/história
[Mh] Termos MeSH secundário: França
História do Século XIX
Itália
Paris
[Pt] Tipo de publicação:HISTORICAL ARTICLE; JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180212
[Lr] Data última revisão:
180212
[Sb] Subgrupo de revista:QIS
[Da] Data de entrada para processamento:171229
[St] Status:MEDLINE


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[PMID]:29283541
[Au] Autor:Thinard-Morel J
[Ti] Título:[In process]
[Ti] Título:Alimentation et soins des maladies de I'Hotel-Dieu de Paris à l'èpoque moderne..
[So] Source:Vesalius;22(2):44-53, 2016 Dec.
[Is] ISSN:1373-4857
[Cp] País de publicação:Belgium
[La] Idioma:fre
[Ab] Resumo:At the end of the Middle Ages, in 1492, the Hôtel-Dieu de Paris was still and establishment of charity intended to receive thepoor which came there to find a shelter and some food. Three centuries later, just before the French Revolution, it became an establishment of care mainly destined to receive the patients, to feed them, take care of them and if possible cure them. This medicalization of the Hôtel-Dieu de Paris is related to the progressive emergence of the medical function, which resulted in the creation and the development of a doctor's and surgeon's profession, but also in the development of the apothecary and its drugs. In this context, the diet plays a central part, because it happens to supplies. It would not be until the eve of the French Revolution that it would be integrated in the doctor's prescription and became a dietetic item.
[Mh] Termos MeSH primário: Hospitais Municipais/história
Médicos/história
[Mh] Termos MeSH secundário: Dieta/história
História do Século XVIII
Seres Humanos
Paris
Preparações Farmacêuticas/história
Farmácia/história
Cirurgiões/história
[Pt] Tipo de publicação:HISTORICAL ARTICLE; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Pharmaceutical Preparations)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180212
[Lr] Data última revisão:
180212
[Sb] Subgrupo de revista:QIS
[Da] Data de entrada para processamento:171229
[St] Status:MEDLINE


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[PMID]:29036185
[Au] Autor:Todd N; Le Fur S; Bougnères P; Valleron AJ
[Ad] Endereço:INSERM U1169, Le Kremlin-Bicêtre, France.
[Ti] Título:Impact of social inequalities at birth on the longevity of children born 1914-1916: A cohort study.
[So] Source:PLoS One;12(10):e0185848, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Testing whether familial socioeconomic status (SES) in childhood is a predictor of mortality has rarely been done on historical cohorts. METHODS: The birth certificates of 4,805 individuals born 1914-1916 in 16 districts of the Paris region were retrieved. The handwritten information provided the occupation of parents, the legitimacy status, life events (e.g. marriage, divorce), and the precise date of death when after 1945 (i.e. age 31 years (y) in the cohort). We used the median age at death (MAD) as a global measure of mortality, then studied separately survival to and after 31 y. Multivariate Imputation by Chained Equations (MICE), Generalized Additive Models (GAMs) and mixed effect Cox models were used. RESULTS: MAD showed large variations according to paternal occupation. The lowest MAD in both sexes was that of workers' children: it was 56.3 y (95% CI: [48.6-62.7]) in men and 67.4 y (95% CI: [60.8-72.7]) in women, respectively (95% CI: 13.4 y [5.7-21.3]) and 12.3 y (95% CI: [4.0-19.2]) below the highest MAD attained. MAD experienced by illegitimate children was 18.9 y (95% CI: [13.3-32.3]) shorter than of legitimate children. The multivariate analysis revealed that in both sexes survival to age 31 y was predicted independently by legitimacy and paternal occupation. Paternal occupation was found significantly associated with mortality after age 31 y in females only: accordingly difference in life expectancy at age 31 y was 4.4 y (95% CI: [1.2-7.6]) between upper class and workers' daughters. CONCLUSIONS: Paternal occupation and legitimacy status were strong predictors of offspring longevity in this one-century historical cohort born during World War One.
[Mh] Termos MeSH primário: Longevidade
Classe Social
[Mh] Termos MeSH secundário: Adulto
Idoso
Idoso de 80 Anos ou mais
Estudos de Coortes
Feminino
Seres Humanos
Ilegitimidade
Expectativa de Vida
Masculino
Meia-Idade
Análise Multivariada
Paris/epidemiologia
Fatores Sexuais
Análise de Sobrevida
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171031
[Lr] Data última revisão:
171031
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171017
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0185848


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[PMID]:28877209
[Au] Autor:Vuillermoz C; Vandentorren S; Brondeel R; Chauvin P
[Ad] Endereço:Sorbonne Universités, UPMC Univ Paris 06, INSERM, Institut Pierre Louis d'épidémiologie et de Santé Publique (IPLESP UMRS 1136), Department of Social Epidemiology, Paris, France.
[Ti] Título:Unmet healthcare needs in homeless women with children in the Greater Paris area in France.
[So] Source:PLoS One;12(9):e0184138, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Despite their poor health status, homeless women encounter many barriers to care. The objectives of our study were to estimate the prevalence of unmet healthcare needs in homeless women and to analyse associated relationships with the following factors: financial and spatial access to care, housing history, migration status, healthcare utilisation, victimization history, caring for children, social network and self-perceived health status. METHODS: We used data from 656 homeless women interviewed during the ENFAMS representative survey of sheltered homeless families, conducted in the Paris region in 2013. Structural equation models (SEM) were used to estimate the impact of various factors on homeless women's unmet healthcare needs. RESULTS: Among those interviewed, 25.1% (95%CI[21.3-29.0]) had at least one unmet healthcare need over the previous year. Most had given up on visiting general practitioners and medical specialists. No association with factors related to financial access or to health insurance status was found. However, food insecurity, poor spatial health access and poor self-perceived health were associated with unmet healthcare needs. Self-perceived health appeared to be affected by victimization and depression. DISCUSSION: The lower prevalence of unmet healthcare needs in homeless women compared with women in stable housing situations suggests that homeless women have lower needs perceptions and/or lower expectations of the healthcare system. This hypothesis is supported by the results from SEM. Strategies to provide better access to care for this population should not only focus on financial interventions but also more broadly on spatial healthcare access, cultural norms, and perceptions of health. Reducing their unmet needs and improving their access to healthcare and prevention must include an improvement in their living, financial and housing conditions.
[Mh] Termos MeSH primário: Necessidades e Demandas de Serviços de Saúde
Pessoas em Situação de Rua
Jovens em Situação de Rua
[Mh] Termos MeSH secundário: Adulto
Criança
Feminino
França
Acesso aos Serviços de Saúde
Necessidades e Demandas de Serviços de Saúde/estatística & dados numéricos
Nível de Saúde
Habitação/provisão & distribuição
Seres Humanos
Entrevistas como Assunto
Meia-Idade
Paris
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171006
[Lr] Data última revisão:
171006
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170907
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0184138


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[PMID]:28777823
[Au] Autor:Thefenne L; de Brier G; Leclerc T; Jourdan C; Nicolas C; Truffaut S; Lapeyre E; Genet F
[Ad] Endereço:Service de Médecine Physique et de Réadaptation, Service de Santé des Armées, Hôpital d'Instruction des Armées Laveran, Marseille, France.
[Ti] Título:Two new risk factors for heterotopic ossification development after severe burns.
[So] Source:PLoS One;12(8):e0182303, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVES: Life after severe burns is conditioned by the remaining sequelae. The pathophysiology and risk factors of Heterotopic Ossification (HO) after burns are still poorly understood. The aim of this study was to determine: 1) the incidence of HO after burns and 2) the risk factors associated with HO development, in a large retrospective study. METHODS: A case-control study of patients admitted to the burns intensive care unit of Percy Hospital, Paris, from the 1st January 2009 to the 31st December 2013 and then admitted to one of three centres specialised in the rehabilitation of patients with burns. Multivariate analysis was carried out to analyse the relationship between HO development and demographic and clinical data. RESULTS: 805 patients were included. 32 patients (4.0%) developed a total of 74 heterotopic ossifications, that is a little higher incidence than the incidence found in the literature. The epidemiological characteristics of the population studied was similar to the literature. HOs were mainly localized around the elbows, followed by the hips, shoulders and knees. Each case-patient was paired with 3 control-patients. There were significant associations between HO development and the length of stay in the burns intensive care unit, the extent and depth of the burns, the occurrence of pulmonary or cutaneous infections, use of curare and use of an air-fluidized bed. CONCLUSION: In addition to recognized risk factors (duration of stay in the intensive care burns unit, extent and depth of burns, pulmonary and cutaneous infections), the use of curare and the use of a fluidized bed (with the duration of use) were significantly associated with HO formation.
[Mh] Termos MeSH primário: Queimaduras/complicações
Articulação do Cotovelo/patologia
Hospitalização/estatística & dados numéricos
Escala de Gravidade do Ferimento
Ossificação Heterotópica/etiologia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Estudos de Casos e Controles
Feminino
Seguimentos
Seres Humanos
Incidência
Masculino
Meia-Idade
Ossificação Heterotópica/epidemiologia
Paris/epidemiologia
Prognóstico
Estudos Retrospectivos
Fatores de Risco
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171010
[Lr] Data última revisão:
171010
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170805
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0182303


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[PMID]:28719696
[Au] Autor:Taran S
[Ad] Endereço:Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
[Ti] Título:The Absurd.
[So] Source:JAMA;318(3):239-240, 2017 Jul 18.
[Is] ISSN:1538-3598
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Pessoas Famosas
Literatura Moderna/história
Filosofia/história
[Mh] Termos MeSH secundário: História do Século XX
Paris
Filosofia Médica
[Pt] Tipo de publicação:BIOGRAPHY; HISTORICAL ARTICLE; JOURNAL ARTICLE; PERSONAL NARRATIVES
[Ps] Nome de pessoa como assunto:Camus A
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170831
[Lr] Data última revisão:
170831
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170719
[St] Status:MEDLINE
[do] DOI:10.1001/jama.2017.5955



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