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  1 / 17228 MEDLINE  
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[PMID]:29175400
[Au] Autor:Kaurin A; Cernilogar Z; Lestan D
[Ad] Endereço:University of Ljubljana, Biotechnical Faculty, Agronomy Department, Jamnikarjeva 101, 1000 Ljubljana, Slovenia.
[Ti] Título:Revitalisation of metal-contaminated, EDTA-washed soil by addition of unpolluted soil, compost and biochar: Effects on soil enzyme activity, microbial community composition and abundance.
[So] Source:Chemosphere;193:726-736, 2018 Feb.
[Is] ISSN:1879-1298
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Soil remediation mitigates hazards from contaminants but could deprive soils of initial biota and enzymes. Historically contaminated acidic soil from Arnoldstein (Austria) and calcareous soil from Meza (Slovenia) were washed with 30 and 100 mmol kg ethylenediaminetetraacetate (EDTA) to remove 78 and 60% of Pb as a main pollutant. Remediation of the Arnoldstein soil decreased urease activity and increased ß-glucosidase activity, measured in a 15-week experiment. The dehydrogenase activity and microbial gene abundances were not significantly impeded compared to the original soil. Conversely, the use of a high dose of EDTA in the Meza soil, necessary for effective remediation of calcareous soils, resulted in pronouncedly decreased enzyme activities (3.2 times on average) and repressed fungal ITS and increased bacterial 16S rRNA gene abundance. Remediation shifted the microbial community composition in both soils. For revitalisation, the remediated soils were amended with compost, inocula of un-contaminated soil and (Arnoldstein soil) biochar enriched with soil extract. Amendments inconsistently affected the Arnoldstein soil: compost increased the dehydrogenase activity and altered the microbial community composition, biochar enhanced the ß-glucosidase activity, and all amendments decreased the microbial abundance (1.6 times on average). In contrast, amendments efficiently revitalised the remediated Meza soil; compost and soil inoculum returned the enzyme activities back to the baseline in the original soil, increased the fungal abundance above that in the original soil and restored the microbial community composition.
[Mh] Termos MeSH primário: Biota
Carvão Vegetal
Compostagem/métodos
Ácido Edético
Recuperação e Remediação Ambiental/métodos
Microbiologia do Solo
Poluentes do Solo/isolamento & purificação
[Mh] Termos MeSH secundário: Áustria
Ácido Edético/farmacologia
Metais/farmacologia
Eslovênia
Solo/química
Poluentes do Solo/análise
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Metals); 0 (Soil); 0 (Soil Pollutants); 0 (biochar); 16291-96-6 (Charcoal); 9G34HU7RV0 (Edetic Acid)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180309
[Lr] Data última revisão:
180309
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171128
[St] Status:MEDLINE


  2 / 17228 MEDLINE  
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[PMID]:29351547
[Au] Autor:Geroldinger A; Sauter SK; Heinze G; Endel G; Dorda W; Duftschmid G
[Ad] Endereço:Center for Medical Statistics, Informatics and Intelligent Systems, Medical University of Vienna, Vienna, Austria.
[Ti] Título:Mortality and continuity of care - Definitions matter! A cohort study in diabetics.
[So] Source:PLoS One;13(1):e0191386, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To demonstrate that when investigating the relevance of continuity of care for patient outcomes, different definitions can lead to contradicting results. METHODS: We used claims data from the regional public health insurer of Lower Austria covering the period from 2008 to 2011. The study sample included subjects with repeated dispensings of anti-diabetic drugs. The continuity of care index was calculated firstly based on a patient's contacts with general practitioners (primary COCI) and secondly based on contacts at all medical disciplines (total COCI). The association of the two continuity of care measures with mortality was assessed in separate univariable and multivariable Cox regression models. RESULTS: Our study sample consisted of 51,717 patients with a median observation time of 3.65 years. The data showed that a high total COCI was associated with increased mortality, while there was no association between primary COCI and mortality. CONCLUSIONS: Measures of continuity of care are highly sensitive to the type of medical disciplines taken into account. The continuity of care index calculated from contacts at all medical disciplines might measure diversity rather than continuity of care.
[Mh] Termos MeSH primário: Continuidade da Assistência ao Paciente
Diabetes Mellitus/mortalidade
Diabetes Mellitus/terapia
[Mh] Termos MeSH secundário: Idoso
Áustria/epidemiologia
Estudos de Coortes
Continuidade da Assistência ao Paciente/estatística & dados numéricos
Diabetes Mellitus/tratamento farmacológico
Feminino
Seres Humanos
Hipoglicemiantes/uso terapêutico
Masculino
Meia-Idade
Análise Multivariada
Modelos de Riscos Proporcionais
Estudos Retrospectivos
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Hypoglycemic Agents)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180305
[Lr] Data última revisão:
180305
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180120
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0191386


  3 / 17228 MEDLINE  
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[PMID]:29291459
[Au] Autor:Quijada NM; Mann E; Wagner M; Rodríguez-Lázaro D; Hernández M; Schmitz-Esser S
[Ad] Endereço:Institute for Milk Hygiene, University of Veterinary Medicine Vienna, Vienna, Austria; Laboratory of Molecular Biology and Microbiology, Instituto Tecnológico Agrario de Castilla y León, Valladolid, Spain.
[Ti] Título:Autochthonous facility-specific microbiota dominates washed-rind Austrian hard cheese surfaces and its production environment.
[So] Source:Int J Food Microbiol;267:54-61, 2018 Feb 21.
[Is] ISSN:1879-3460
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Cheese ripening involves the succession of complex microbial communities that are responsible for the organoleptic properties of the final products. The food processing environment can act as a source of natural microbial inoculation, especially in traditionally manufactured products. Austrian Vorarlberger Bergkäse (VB) is an artisanal washed-rind hard cheese produced in the western part of Austria without the addition of external ripening cultures. Here, the composition of the bacterial communities present on VB rinds and on different processing surfaces from two ripening cellars was assessed by near full length 16S rRNA gene amplification, cloning and sequencing. Non-inoculated aerobic bacteria dominated all surfaces in this study. VB production conditions (long ripening time, high salt concentration and low temperatures) favor the growth of psychro- and halotolerant bacteria. Several bacterial groups, such as coryneforms, Staphylococcus equorum and Halomonas dominated VB and were also found on most environmental surfaces. Analysis of OTUs shared between different surfaces suggests that VB rind bacteria are inoculated naturally during the ripening from the processing environment and that cheese surfaces exert selective pressure on these communities, as only those bacteria better adapted flourished on VB rinds. This study analyzed VB processing environment microbiota and its relationship with VB rinds for the first time, elucidating that the processing environment and the cheese microbiota should be considered as microbiologically linked ecosystems with the goal of better defining the events that take place during cheese maturation.
[Mh] Termos MeSH primário: Fenômenos Fisiológicos Bacterianos
Queijo/microbiologia
Microbiologia Ambiental
[Mh] Termos MeSH secundário: Áustria
Bactérias/genética
Manipulação de Alimentos
Microbiota/genética
Microbiota/fisiologia
RNA Ribossômico 16S/genética
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (RNA, Ribosomal, 16S)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180305
[Lr] Data última revisão:
180305
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180102
[St] Status:MEDLINE


  4 / 17228 MEDLINE  
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[PMID]:27773450
[Au] Autor:Kovarik JJ; Kopecky C; Antlanger M; Domenig O; Kaltenecker CC; Werzowa J; Hecking M; Mahr S; Grömmer M; Wallner C; Aumayr K; Kain R; Zuckermann A; Poglitsch M; Säemann MD
[Ad] Endereço:Department of Internal Medicine III, Clinical Division of Nephrology and Dialysis, Medical University of Vienna, Vienna, Austria.
[Ti] Título:Effects of angiotensin-converting-enzyme inhibitor therapy on the regulation of the plasma and cardiac tissue renin-angiotensin system in heart transplant patients.
[So] Source:J Heart Lung Transplant;36(3):355-365, 2017 Mar.
[Is] ISSN:1557-3117
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Angiotensin-converting enzyme (ACE) inhibitors (ACEis) are beneficial in patients with heart failure, yet their role after heart transplantation (HTx) remains ambiguous. Particularly, the effects of ACEis on plasma and cardiac metabolites of the "classical" and "alternative" renin-angiotensin system (RAS) in HTx patients are unknown. METHODS: This cross-sectional study used a novel mass spectrometry-based approach to analyze plasma and tissue RAS regulation in homogenates of heart biopsy specimens from 10 stable HTx patients without RAS blockade and in 15 patients with ACEi therapy. Angiotensin (Ang) levels in plasma and Ang formation rates in biopsy tissue homogenates were measured. RESULTS: Plasma Ang II formation is exclusively ACE dependent, whereas cardiac Ang II formation is primarily chymase dependent in HTx patients. ACEi therapy substantially increased plasma Ang-(1-7), the key effector of the alternative RAS, leaving plasma Ang II largely intact. Importantly, neprilysin and prolyl-carboxypeptidase but not angiotensin converting enzyme 2 are essential for cardiac tissue Ang-(1-7) formation. CONCLUSION: ACE is the key enzyme for the generation of plasma Ang II, whereas chymase is responsible for cardiac tissue production of Ang II. Furthermore, our findings reveal that neprilysin and prolyl-carboxypeptidase are the essential cardiac enzymes for the alternative RAS after HTx. These novel insights into the versatile regulation of the RAS in HTx patients might affect future therapeutic avenues, such as chymase and neprilysin inhibition, beyond classical Ang II blockade.
[Mh] Termos MeSH primário: Inibidores da Enzima Conversora de Angiotensina/administração & dosagem
Rejeição de Enxerto/prevenção & controle
Insuficiência Cardíaca/sangue
Transplante de Coração/métodos
Sistema Renina-Angiotensina/efeitos dos fármacos
[Mh] Termos MeSH secundário: Idoso
Áustria
Biópsia por Agulha
Estudos Transversais
Ecocardiografia
Feminino
Seguimentos
Sobrevivência de Enxerto
Insuficiência Cardíaca/diagnóstico por imagem
Insuficiência Cardíaca/cirurgia
Transplante de Coração/efeitos adversos
Seres Humanos
Imuno-Histoquímica
Masculino
Meia-Idade
Valores de Referência
Medição de Risco
Papel (Figurativo)
Resultado do Tratamento
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Angiotensin-Converting Enzyme Inhibitors)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180228
[Lr] Data última revisão:
180228
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161025
[St] Status:MEDLINE


  5 / 17228 MEDLINE  
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[PMID]:28449276
[Au] Autor:Eggers CCJ; Bocksrucker C; Seyfang L; Austrian Stroke Unit Registry Collaborators
[Ad] Endereço:Department of Neurology, Hospital Barmherzige Brüder, Linz, Austria.
[Ti] Título:The efficacy of thrombolysis in lacunar stroke - evidence from the Austrian Stroke Unit Registry.
[So] Source:Eur J Neurol;24(6):780-787, 2017 Jun.
[Is] ISSN:1468-1331
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND AND PURPOSE: Intravenous thrombolysis (ivT) with recombinant tissue plasminogen activator is established in acute ischaemic stroke. Little is known, however, about its efficacy in different stroke subtypes. METHODS: A retrospective analysis of 128 733 patients from the Austrian Stroke Unit Registry was performed. Patients were classified as lacunar (LacS) or non-lacunar ischaemic stroke (nonLacS) by use of the clinical syndrome and technical findings. Outcome parameters were the short term improvement in the stroke unit [the difference of the National Institutes of Health Stroke Scale (NIHSS) score at admission and at discharge] and the modified Rankin Scale (mRS) score at 3 months. Patients were assigned to four groups according to thrombolysis and stroke subtype. To control for confounding, patients were matched for variables identified with impact outcome and for variables of general interest (NIHSS at admission, mRS before stroke and general risk factors). RESULTS: There were four matched groups of 401 cases each. In LacS median short term improvement was 3 [interquartile range (IQR) 2-5] NIHSS points in the thrombolysed patients and 2 (IQR 1-4) in the non-thrombolysed patients (P < 0.001). In the nonLacS groups median short term improvement was 3 (IQR 1-5) in the thrombolysed and 2 (IQR 0-4) in the non-thrombolysed patients (P < 0.001). At 3-month follow-up, ivT was significantly associated with a better functional outcome in LacS (P < 0.001) and nonLacS patients (P < 0.001). Taking magnetic resonance imaging as a requirement for stroke subtyping led to similar results. CONCLUSIONS: Patients with both lacunar and non-lacunar stroke benefitted from ivT. The degree of improvement was similar in both groups.
[Mh] Termos MeSH primário: Isquemia Encefálica/tratamento farmacológico
Fibrinolíticos/uso terapêutico
Acidente Vascular Cerebral Lacunar/tratamento farmacológico
Terapia Trombolítica
Ativador de Plasminogênio Tecidual/uso terapêutico
[Mh] Termos MeSH secundário: Adulto
Idoso
Idoso de 80 Anos ou mais
Áustria
Feminino
Seres Humanos
Masculino
Meia-Idade
Sistema de Registros
Estudos Retrospectivos
Fatores de Risco
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Fibrinolytic Agents); EC 3.4.21.68 (Tissue Plasminogen Activator)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180212
[Lr] Data última revisão:
180212
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170428
[St] Status:MEDLINE
[do] DOI:10.1111/ene.13288


  6 / 17228 MEDLINE  
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[PMID]:27779467
[Au] Autor:Meltzer E; Paran Y; Lustig Y; Stienlauf S; Weinberger M; Schwartz E
[Ti] Título:Travel-Related Tick-Borne Encephalitis, Israel, 2006-2014.
[So] Source:Emerg Infect Dis;23(1):119-121, 2017 01.
[Is] ISSN:1080-6059
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:During 2006-2014, four tick-borne encephalitis (TBE) cases occurred among Israeli travelers. We calculated TBE incidence at 321.0, 45.0, 13.2, and 7.5 cases/100,000 travelers/year of travel to Sweden, Switzerland, Austria, and Germany, respectively. TBE incidence among travelers to these destinations appears to justify TBE vaccination in accordance with World Health Organization recommendations.
[Mh] Termos MeSH primário: Vetores Aracnídeos/virologia
Encefalite Transmitida por Carrapatos/epidemiologia
Encefalite Transmitida por Carrapatos/transmissão
Carrapatos/virologia
Viagem
[Mh] Termos MeSH secundário: Animais
Áustria/epidemiologia
Vírus da Encefalite Transmitidos por Carrapatos/patogenicidade
Vírus da Encefalite Transmitidos por Carrapatos/fisiologia
Encefalite Transmitida por Carrapatos/prevenção & controle
Alemanha/epidemiologia
Seres Humanos
Incidência
Israel/epidemiologia
Suécia/epidemiologia
Suíça/epidemiologia
Vacinação
Vacinas Virais/administração & dosagem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Viral Vaccines)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180209
[Lr] Data última revisão:
180209
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161026
[St] Status:MEDLINE
[do] DOI:10.3201/eid2301.160888


  7 / 17228 MEDLINE  
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[PMID]:28468682
[Au] Autor:Tran US; Berger N; Arendasy ME; Greitemeyer T; Himmelbauer M; Hutzler F; Kraft HG; Oettl K; Papousek I; Vitouch O; Voracek M
[Ad] Endereço:Department of Basic Psychological Research and Research Methods, School of Psychology, University of Vienna, Vienna, Austria. ulrich.tran@univie.ac.at.
[Ti] Título:Unto the third generation: evidence for strong familial aggregation of physicians, psychologists, and psychotherapists among first-year medical and psychology students in a nationwide Austrian cohort census.
[So] Source:BMC Med Educ;17(1):81, 2017 May 03.
[Is] ISSN:1472-6920
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Medical students present higher numbers of physician relatives than expectable from the total population prevalence of physicians. Evidence for such a familial aggregation effect of physicians has emerged in investigations from the Anglo-American, Scandinavian, and German-speaking areas. In particular, past data from Austria suggest a familial aggregation of the medical, as well as of the psychological and psychotherapeutic, professions among medical and psychology undergraduates alike. Here, we extend prior related studies by examining (1) the extent to which familial aggregation effects apply to the whole nation-wide student census of all relevant (eight) public universities in Austria; (2) whether effects are comparable for medical and psychology students; (3) and whether these effects generalize to relatives of three interrelated health professions (medicine, psychology, and psychotherapy). METHODS: We investigated the familial aggregation of physicians, psychologists, and psychotherapists, based on an entire cohort census of first-year medical and psychology students (n = 881 and 920) in Austria with generalized linear mixed models. RESULTS: For both disciplines, we found strong familial aggregation of physicians, psychologists, and psychotherapists. As compared with previous results, directionally opposite time trends within disciplines emerged: familial aggregation of physicians among medical students has decreased, whilst familial aggregation of psychologists among psychology students has increased. Further, there were sex-of-relative effects (i.e., more male than female physician relatives), but no substantial sex-of-student effects (i.e., male and female students overall reported similar numbers of relatives for all three professions of interest). In addition, there were age-benefit effects, i.e., students with a relative in the medical or the psychotherapeutic profession were younger than students without, thus suggesting earlier career decisions. CONCLUSIONS: The familial aggregation of physicians, psychologists, and psychotherapists is high among medical and psychology undergraduates in Austria. Discussed are implications of these findings (e.g., gender equity, feminization of the medical field, ideas for curricular implementation and student counselling), study limitations, and avenues for future research.
[Mh] Termos MeSH primário: Censos
Educação Médica
Família
Psicologia
Psicoterapia
Estudantes de Medicina
[Mh] Termos MeSH secundário: Adolescente
Adulto
Áustria
Estudos de Coortes
Feminino
Seres Humanos
Masculino
Psicologia/educação
Psicoterapia/educação
Estudantes de Medicina/estatística & dados numéricos
Inquéritos e Questionários
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180123
[Lr] Data última revisão:
180123
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170505
[St] Status:MEDLINE
[do] DOI:10.1186/s12909-017-0921-4


  8 / 17228 MEDLINE  
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[PMID]:29239581
[Au] Autor:Luger E; Haider S; Kapan A; Schindler K; Lackinger C; Dorner TE
[Ti] Título:Association Between Nutritional Status and Quality of Life in (Pre) Frail Community-Dwelling Older Persons.
[So] Source:J Frailty Aging;5(3):141-8, 2016.
[Is] ISSN:2260-1341
[Cp] País de publicação:France
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: For developed countries, healthy aging is one of the challenges and the number of healthy life years and especially the quality of life (QoL) are important. OBJECTIVE: This study aimed to assess the association between nutritional status and different domains of QoL in (pre)frail community-dwelling elders. DESIGN: Baseline data from persons, who participated in a 12-week nutritional and physical training intervention program, conducted from September 2013 - July 2015. Setting: (Pre)frail community-dwelling elders living in Vienna, Austria. PARTICIPANTS: A total of 83 older persons living at home, 12 men and 71 women (86%) aged 65 to 98 years. Measurements: Structured interviews were conducted at participants' homes. Mini Nutritional Assessment® long-form (MNA®-LF) was used to investigate the nutritional status. The QoL domains were assessed with the World Health Organization Quality of Life questionnaires. Simple and multiple linear regression analyses were performed to evaluate the association between nutritional status and QoL domains, adjusted for possible confounders. RESULTS: 45% of the participants were at risk of malnutrition and 3% were malnourished. Compared to normal nourished people, persons who had an impaired nutritional status, significantly differed in the QoL domain 'autonomy' with mean (SD) scores of 50.0 (14.9) vs. 57.3 (13.7); p=0.022 and in the QoL domain 'social participation' with scores of 40.1 (13.6) vs. 47.0 (11.2); p=0.014, respectively. According to linear regression analyses, the MNA®-LF score was significantly associated with 'overall QoL' (ß=0.26; p=0.016) and the QoL domains 'physical health' (ß=0.23; p=0.036), 'autonomy' (ß=0.27; p=0.015), and 'social participation' (ß=0.28; p=0.013).CONCLUSIONS: There was a significant association between nutritional status and QoL in elderly (pre)frail community-dwelling people, in particular for the QoL domains 'autonomy' and 'social participation'. However, it remains unclear whether malnutrition was the cause or the consequence, or it was mediated through a third possible factor e.g. the functional status.
[Mh] Termos MeSH primário: Idoso Fragilizado/estatística & dados numéricos
Vida Independente
Estado Nutricional
Qualidade de Vida
[Mh] Termos MeSH secundário: Idoso
Idoso de 80 Anos ou mais
Áustria/epidemiologia
Feminino
Avaliação Geriátrica
Seres Humanos
Entrevistas como Assunto
Masculino
Desnutrição/epidemiologia
Avaliação Nutricional
Inquéritos e Questionários
[Pt] Tipo de publicação:RESEARCH SUPPORT, NON-U.S. GOV'T; JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180115
[Lr] Data última revisão:
180115
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171215
[St] Status:MEDLINE


  9 / 17228 MEDLINE  
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[PMID]:28455331
[Au] Autor:Schötta AM; Wijnveld M; Stockinger H; Stanek G
[Ad] Endereço:Institute for Hygiene and Applied Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria anna-margarita.schoetta@meduniwien.ac.at.
[Ti] Título:Approaches for Reverse Line Blot-Based Detection of Microbial Pathogens in Ixodes ricinus Ticks Collected in Austria and Impact of the Chosen Method.
[So] Source:Appl Environ Microbiol;83(13), 2017 Jul 01.
[Is] ISSN:1098-5336
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Ticks transmit a large number of pathogens capable of causing human disease. In this study, the PCR-reverse line blot (RLB) method was used to screen for pathogens in a total of 554 ticks collected from all provinces of Austria. These pathogens belong to the genera , , / (including " Neoehrlichia"), , and The pathogens with the highest detected prevalence were spirochetes of the complex, in 142 ticks (25.6%). (80/142) was the most frequently detected species, followed by (38/142) and (36/142). , , and were found in 28 ticks, 5 ticks, and 1 tick, respectively. spp. were detected in 93 ticks (16.8%): (39/93), (38/93), (2/93), and (1/93). Thirteen samples remain uncharacterized. " Neoehrlichia mikurensis," spp. ( , , ), and were found in 4.5%, 2.7%, and 0.7%, respectively. was not detected. Multiple microorganisms were detected in 40 ticks (7.2%), and the cooccurrence of spp. and " Neoehrlichia mikurensis" showed a significant positive correlation. We also compared different PCR-RLBs for detection of and spp. and showed that different detection approaches provide highly diverse results, indicating that analysis of environmental samples remains challenging. This study determined the wide spectrum of tick-borne bacterial and protozoal pathogens that can be encountered in Austria. Surveillance of (putative) pathogenic microorganisms occurring in the environment is of medical importance, especially when those agents can be transmitted by ticks and cause disease. The observation of significant coinfections of certain microorganisms in field-collected ticks is an initial step to an improved understanding of microbial interactions in ticks. In addition, we show that variations in molecular detection methods, such as in primer pairs and target genes, can considerably influence the final results. For instance, detection of certain genospecies of borreliae may be better or worse by one method or the other, a fact of great importance for future screening studies.
[Mh] Termos MeSH primário: Anaplasma/isolamento & purificação
Southern Blotting/métodos
Borrelia/isolamento & purificação
Ixodes/microbiologia
Reação em Cadeia da Polimerase/métodos
Rickettsia/isolamento & purificação
[Mh] Termos MeSH secundário: Anaplasma/classificação
Anaplasma/genética
Animais
Áustria
Borrelia/classificação
Borrelia/genética
DNA Bacteriano/genética
Rickettsia/classificação
Rickettsia/genética
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Bacterial)
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171225
[Lr] Data última revisão:
171225
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170430
[St] Status:MEDLINE


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[PMID]:28462740
[Au] Autor:Jadraque PP; Carter KC
[Ad] Endereço:Department of Epidemiology,Hospital General de La Palma,Breña Alta, Canarias 38710,Spain.
[Ti] Título:What happened at Vienna's Allgemeines Krankenhaus after Semmelweis's contract as Assistant in the First Maternity Division was terminated?
[So] Source:Epidemiol Infect;145(10):2144-2151, 2017 07.
[Is] ISSN:1469-4409
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Ignác Fülöp Semmelweis is famous for dramatically reducing puerperal mortality while he was an Assistant in Vienna's largest hospital, the Allgemeines Krankenhaus; he did this, mainly, by requiring medical personnel to disinfect their hands by washing in a chlorine solution. But Semmelweis was soon removed from his post as assistant. The conventional view, which is suggested by Semmelweis's own account, is that his contemporaries were skeptical of his results, that he was marginalized and that once he was no longer directly responsible for caring for maternity patients, puerperal mortality returned to its former high levels. In fact, the situation appears to have been quite different. In this paper, we calculate and discuss the number of deaths at the Allgemeines maternity clinic after Semmelweis was removed from his position. As we will see, his successors maintained a relatively low mortality rate roughly consistent with the rate Semmelweis himself achieved. This suggests that the chlorine washings were probably still used conscientiously after he left and that the opposition he encountered had other sources than doubts about the effectiveness of the chlorine washings.
[Mh] Termos MeSH primário: Cloro/uso terapêutico
Higiene das Mãos/história
Maternidades/história
[Mh] Termos MeSH secundário: Áustria
Cloro/história
História do Século XIX
[Pt] Tipo de publicação:BIOGRAPHY; HISTORICAL ARTICLE; JOURNAL ARTICLE
[Ps] Nome de pessoa como assunto:Semmelweis IF
[Nm] Nome de substância:
4R7X1O2820 (Chlorine)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:171125
[Lr] Data última revisão:
171125
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170503
[St] Status:MEDLINE
[do] DOI:10.1017/S0950268817000875



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