Base de dados : MEDLINE
Pesquisa : Z01.542.248 [Categoria DeCS]
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[PMID]:29360839
[Au] Autor:Petkeviciute R; Stunzenas V; Staneviciute G
[Ad] Endereço:P. B. Sivickis Laboratory of Parasitology, Nature Research Centre, Vilnius, Lithuania.
[Ti] Título:Comments on species divergence in the genus Sphaerium (Bivalvia) and phylogenetic affinities of Sphaerium nucleus and S. corneum var. mamillanum based on karyotypes and sequences of 16S and ITS1 rDNA.
[So] Source:PLoS One;13(1):e0191427, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Chromosome, 16S and ITS1 rDNA sequence analyses were used to obtain reliable diagnostic characters and to clarify phylogenetic relationships of sphaeriid bivalves of the genus Sphaerium. The species studied were found to be diploid, with modal number 2n = 28 in S. nucleus and 2n = 30 in S. corneum var. mamillanum. Small, biarmed, C- negative B chromosomes were found in all studied populations of both species. Karyological and molecular markers revealed no differences between S. corneum s. str. and S. corneum var. mamillanum. No intraspecific differences were found in the basic karyotype of S. nucleus. Molecular analyses, however, uncovered three genetically distinct ITS1 lineages: one comprised of samples from Lithuania, Slovakia, and Russia, another from Czech, and a third from Ukraine. Additionally to known 16S haplotype from Ukraine, three new 16S haplotypes of S. nucleus were detected: one in the samples from Lithuania and Russia, one in Slovakian and one in Czech population. In the ITS1 phylogenetic tree, all branches of S. nucleus clustered in one clade. In the 16S phylogenetic tree, however, the haplotype of Czech S. nucleus formed a separate branch, distant from three other haplotypes of S. nucleus. Molecular results indicate that in the context of the Evolutionary Species Concept the S. nucleus morphospecies may represent a complex of separate taxa, however referring on the Biological Species Concept the genetic lineages could represent the intraspecific variability.
[Mh] Termos MeSH primário: Bivalves/classificação
Bivalves/genética
[Mh] Termos MeSH secundário: Animais
DNA Espaçador Ribossômico/genética
Europa Oriental
Evolução Molecular
Especiação Genética
Genética Populacional
Cariotipagem
Filogenia
RNA Ribossômico 16S/genética
Especificidade da Espécie
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (DNA, Ribosomal Spacer); 0 (RNA, Ribosomal, 16S)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180227
[Lr] Data última revisão:
180227
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180124
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0191427


  2 / 4025 MEDLINE  
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[PMID]:29247338
[Au] Autor:Kemenesi G; Kurucz K; Zana B; Földes F; Urbán P; Vlaschenko A; Kravchenko K; Budinski I; Szodoray-Parádi F; Bücs S; Jére C; Csosz I; Szodoray-Parádi A; Estók P; Görföl T; Boldogh S; Jakab F
[Ad] Endereço:Virological Research Group, János Szentágothai Research Centre, University of Pécs, Pécs, Hungary. kemenesi.gabor@gmail.com.
[Ti] Título:Diverse replication-associated protein encoding circular DNA viruses in guano samples of Central-Eastern European bats.
[So] Source:Arch Virol;163(3):671-678, 2018 Mar.
[Is] ISSN:1432-8798
[Cp] País de publicação:Austria
[La] Idioma:eng
[Ab] Resumo:Circular replication-associated protein encoding single-stranded DNA (CRESS DNA) viruses are increasingly recognized worldwide in a variety of samples. Representative members include well-described veterinary pathogens with worldwide distribution, such as porcine circoviruses or beak and feather disease virus. In addition, numerous novel viruses belonging to the family Circoviridae with unverified pathogenic roles have been discovered in different human samples. Viruses of the family Genomoviridae have also been described as being highly abundant in different faecal and environmental samples, with case reports showing them to be suspected pathogens in human infections. In order to investigate the genetic diversity of these viruses in European bat populations, we tested guano samples from Georgia, Hungary, Romania, Serbia and Ukraine. This resulted in the detection of six novel members of the family Circoviridae and two novel members of the family Genomoviridae. Interestingly, a gemini-like virus, namely niminivirus, which was originally found in raw sewage samples in Nigeria, was also detected in our samples. We analyzed the nucleotide composition of members of the family Circoviridae to determine the possible host origins of these viruses. This study provides the first dataset on CRESS DNA viruses of European bats, and members of several novel viral species were discovered.
[Mh] Termos MeSH primário: Quirópteros/virologia
Circoviridae/genética
Infecções por Vírus de DNA/epidemiologia
Vírus de DNA/genética
DNA de Cadeia Simples/genética
DNA Viral/genética
Genoma Viral
[Mh] Termos MeSH secundário: Sequência de Aminoácidos
Animais
Circoviridae/classificação
Circoviridae/isolamento & purificação
Infecções por Vírus de DNA/transmissão
Infecções por Vírus de DNA/virologia
Vírus de DNA/classificação
Vírus de DNA/isolamento & purificação
Europa Oriental/epidemiologia
Fezes/virologia
Georgia/epidemiologia
Seres Humanos
Filogenia
Replicação Viral
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Single-Stranded); 0 (DNA, Viral)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180220
[Lr] Data última revisão:
180220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171217
[St] Status:MEDLINE
[do] DOI:10.1007/s00705-017-3678-5


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[PMID]:27776499
[Au] Autor:Brodziak A; Rózyk-Myrta A; Wolinska A
[Ad] Endereço:Institute of Occupational Medicine and Environmental Health, Koscielna 13, 41-200, Sosnowiec, Poland. andrzejbrodziak@wp.pl.
[Ti] Título:Does the recent intensification of nationalistic and xenophobic attitudes in Eastern European countries adversely affect public mental health?
[So] Source:BMC Public Health;16(1):1115, 2016 10 24.
[Is] ISSN:1471-2458
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The authors postulate that the recent intensification of the nationalist and xenophobic attitude in Poland and other Eastern European countries is detrimental to public mental health. The xenophobic attitude is accompanied by a higher incidence of anxiety and depression, disputes due to the polarization of opinions, a sense of embarrassment and a sense of contradictions with so-called Christian values, unfavorable demographic predictions and reduced life satisfaction. DISCUSSION: The authors attempt to describe the sequence of adverse events that led to the intensification of xenophobia and characterize the current state of public mental health in European countries. They formulate and propose possible actions which could counteract the consequences of that transformation. SHORT CONCLUSION: The actions which may be undertaken to counteract the deterioration of public mental health can be based on the recommendations of so-called 'positive psychology' and 'positive psychiatry' as well as the principles of strengthening local social capital.
[Mh] Termos MeSH primário: Atitude
Saúde Mental
Saúde Pública
Xenofobia/psicologia
[Mh] Termos MeSH secundário: Ansiedade/etiologia
Demografia
Depressão/etiologia
Europa (Continente)
Europa Oriental
Seres Humanos
Incidência
Satisfação Pessoal
Polônia
Grupos Populacionais
Valores Sociais
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1708
[Cu] Atualização por classe:171227
[Lr] Data última revisão:
171227
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161026
[St] Status:MEDLINE


  4 / 4025 MEDLINE  
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[PMID]:28883106
[Ti] Título:African swine fever in eastern Europe: the risk to the UK.
[So] Source:Vet Rec;181(10):261-262, 2017 Sep 09.
[Is] ISSN:2042-7670
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:This article has been prepared by Helen Roberts of the Defra/APHA International Disease Monitoring team.
[Mh] Termos MeSH primário: Febre Suína Africana/epidemiologia
Surtos de Doenças/veterinária
Vigilância de Evento Sentinela/veterinária
[Mh] Termos MeSH secundário: Animais
Europa Oriental/epidemiologia
Risco
Sus scrofa/virologia
Suínos
Reino Unido/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170918
[Lr] Data última revisão:
170918
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170909
[St] Status:MEDLINE
[do] DOI:10.1136/vr.j4174


  5 / 4025 MEDLINE  
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[PMID]:28711578
[Au] Autor:Dimitrova N; Znaor A; Agius D; Eser S; Sekerija M; Ryzhov A; Primic-Zakelj M; Coebergh JW; SEE; Working Group
[Ad] Endereço:Bulgarian National Cancer Registry, Sofia, Bulgaria. Electronic address: dimitrova.nadia@gmail.com.
[Ti] Título:Breast cancer in South-Eastern European countries since 2000: Rising incidence and decreasing mortality at young and middle ages.
[So] Source:Eur J Cancer;83:43-55, 2017 Sep.
[Is] ISSN:1879-0852
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Marked variations exist in the incidence and mortality trends of major cancers in South-Eastern European (SEE) countries which have now been detailed by age for breast cancer (BC) to seek clues for improvement. METHODS: We brought together and analysed data from 14 cancer registries (CRs), situated in SEE countries or directly adjacent. Age-standardised rate at world standard (ASRw) and truncated incidence and mortality rates during 2000-2010 by year, and for four age groups, were calculated. Average annual percentage change of rates was estimated using Joinpoint regression. RESULTS: Annual incidence rates increased significantly in countries and age groups, by 2-4% (15-39 years), 2-5% (40-49), 1-4% (50-69) and 1-6% (at 70+). Mortality rates decreased significantly in all age-groups in most countries, but increased up to 5% annually above age 55 in Ukraine, Serbia, Moldova and Cyprus. The BC data quality was evaluated by internationally agreed indicators which appeared suboptimal for Moldova, Bosnia and Herzegovina and Romania. CONCLUSION: The observed variations of incidence trends reflect the influence of risk factors, as well as levels of early detection activities (screening). While mortality rates were mostly decreasing, probably due to improved cancer care and introduction of more effective systemic treatment regimens, the worrying increasing mortality trends in the 55-plus age groups in some countries have to be addressed by health professionals and policymakers. In order to assess and monitor the effects of cancer control activities in the region, the CRs need substantial investments.
[Mh] Termos MeSH primário: Neoplasias da Mama/epidemiologia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Distribuição por Idade
Idoso
Europa Oriental/epidemiologia
Feminino
Seres Humanos
Incidência
Meia-Idade
Mortalidade/tendências
Análise de Regressão
Fatores de Risco
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170911
[Lr] Data última revisão:
170911
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170717
[St] Status:MEDLINE


  6 / 4025 MEDLINE  
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[PMID]:28530040
[Au] Autor:Bailey H; Cruz MLS; Songtaweesin WN; Puthanakit T
[Ad] Endereço:Population, Policy and Practice Programme, UCL Great Ormond Street Institute of Child Health, University College London, London, UK.
[Ti] Título:Adolescents with HIV and transition to adult care in the Caribbean, Central America and South America, Eastern Europe and Asia and Pacific regions.
[So] Source:J Int AIDS Soc;20(Suppl 3):21475, 2017 05 16.
[Is] ISSN:1758-2652
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: The HIV epidemics in the Caribbean, Central America and South America (CCASA), Eastern Europe (EE) and Asia and Pacific (AP) regions are diverse epidemics affecting different key populations in predominantly middle-income countries. This narrative review describes the populations of HIV-positive youth approaching adolescence and adulthood in CCASA, EE and AP, what is known of their outcomes in paediatric and adult care to date, ongoing research efforts and future research priorities. METHODS: We searched PubMed and abstracts from recent conferences and workshops using keywords including HIV, transition and adolescents, to identify published data on transition outcomes in CCASA, EE and AP. We also searched within our regional clinical/research networks for work conducted in this area and presented at local or national meetings. To give insight into future research priorities, we describe published data on characteristics and health status of young people as they approach age of transition, as a key determinant of health in early adulthood, and information available on current transition processes. RESULTS AND DISCUSSION: The perinatally HIV-infected populations in these three regions face a range of challenges including parental death and loss of family support; HIV-related stigma and socio-economic disparities; exposure to maternal injecting drug use; and late disclosure of HIV status. Behaviourally HIV-infected youth often belong to marginalized sub-groups, with particular challenges accessing services and care. Differences between and within countries in characteristics of HIV-positive youth and models of care need to be considered in comparisons of outcomes in young adulthood. The very little data published to date on transition outcomes across these three regions highlight some emerging issues around adherence, virological failure and loss to follow-up, alongside examples of programmes which have successfully supported adolescents to remain engaged with services and virologically suppressed. CONCLUSIONS: Limited data available indicate uneven outcomes in paediatric services and some shared challenges for adolescent transition including retention in care and adherence. The impact of issues specific to low prevalence, concentrated epidemic settings are poorly understood to date. Outcome data are urgently needed to guide management strategies and advocate for service provision in these regions.
[Mh] Termos MeSH primário: Infecções por HIV
Transição para Assistência do Adulto
[Mh] Termos MeSH secundário: Adolescente
Adulto
Pesquisa Biomédica
Região do Caribe/epidemiologia
América Central/epidemiologia
Criança
Epidemias
Europa Oriental/epidemiologia
Feminino
Infecções por HIV/epidemiologia
Nível de Saúde
Seres Humanos
Masculino
Estigma Social
América do Sul/epidemiologia
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171011
[Lr] Data última revisão:
171011
[Sb] Subgrupo de revista:IM; X
[Da] Data de entrada para processamento:170523
[St] Status:MEDLINE
[do] DOI:10.7448/IAS.20.4.21475


  7 / 4025 MEDLINE  
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[PMID]:28441361
[Au] Autor:Giambi C; Del Manso M; Dente MG; Napoli C; Montaño-Remacha C; Riccardo F; Declich S; Network For The Control Of Cross-Border Health Threats In The Mediterranean Basin And Black Sea For The ProVacMed Project
[Ad] Endereço:National Center for Epidemiology, Surveillance and Health Promotion, National Institute of Health (Istituto Superiore di Sanità, ISS), viale Regina Elena, 299, 00161 Rome, Italy. cristina.giambi@iss.it.
[Ti] Título:Immunization Strategies Targeting Newly Arrived Migrants in Non-EU Countries of the Mediterranean Basin and Black Sea.
[So] Source:Int J Environ Res Public Health;14(5), 2017 Apr 25.
[Is] ISSN:1660-4601
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:: The World Health Organization recommends that host countries ensure appropriate vaccinations to refugees, asylum seekers and migrants. However, information on vaccination strategies targeting migrants in host countries is limited. : In 2015-2016 we carried out a survey among national experts from governmental bodies of 15 non-EU countries of the Mediterranean and Black Sea in order to document and share national vaccination strategies targeting newly arrived migrants. : Four countries reported having regulations/procedures supporting the immunization of migrants at national level, one at sub-national level and three only targeting specific population groups. Eight countries offer migrant children all the vaccinations included in their national immunization schedule; three provide only selected vaccinations, mainly measles and polio vaccines. Ten and eight countries also offer selected vaccinations to adolescents and adults respectively. Eight countries provide vaccinations at the community level; seven give priority vaccines in holding centres or at entry sites. Data on administered vaccines are recorded in immunization registries in nine countries. : Although differing among countries, indications for immunizing migrants are in place in most of them. However, we cannot infer from our findings whether those strategies are currently functioning and whether barriers to their implementation are being faced. Further studies focusing on these aspects are needed to develop concrete and targeted recommendations for action. Since migrants are moving across countries, development of on-line registries and cooperation between countries could allow keeping track of administered vaccines in order to appropriately plan immunization series and avoid unnecessary vaccinations.
[Mh] Termos MeSH primário: Imunização/métodos
Refugiados
Migrantes
[Mh] Termos MeSH secundário: Adolescente
Adulto
África do Norte
Idoso
Criança
Pré-Escolar
Europa Oriental
Seres Humanos
Imunização/legislação & jurisprudência
Lactente
Recém-Nascido
Meia-Idade
Oriente Médio
Refugiados/estatística & dados numéricos
Migrantes/estatística & dados numéricos
Vacinação/legislação & jurisprudência
Vacinação/métodos
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170824
[Lr] Data última revisão:
170824
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170426
[St] Status:MEDLINE


  8 / 4025 MEDLINE  
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[PMID]:28231316
[Au] Autor:Vasilakis DP; Whitfield DP; Kati V
[Ad] Endereço:Department of Environmental and Natural Resources Management, University of Patras, Agrinio, Aitoloakarnania, Greece.
[Ti] Título:A balanced solution to the cumulative threat of industrialized wind farm development on cinereous vultures (Aegypius monachus) in south-eastern Europe.
[So] Source:PLoS One;12(2):e0172685, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Wind farm development can combat climate change but may also threaten bird populations' persistence through collision with wind turbine blades if such development is improperly planned strategically and cumulatively. Such improper planning may often occur. Numerous wind farms are planned in a region hosting the only cinereous vulture population in south-eastern Europe. We combined range use modelling and a Collision Risk Model (CRM) to predict the cumulative collision mortality for cinereous vulture under all operating and proposed wind farms. Four different vulture avoidance rates were considered in the CRM. Cumulative collision mortality was expected to be eight to ten times greater in the future (proposed and operating wind farms) than currently (operating wind farms), equivalent to 44% of the current population (103 individuals) if all proposals are authorized (2744 MW). Even under the most optimistic scenario whereby authorized proposals will not collectively exceed the national target for wind harnessing in the study area (960 MW), cumulative collision mortality would still be high (17% of current population) and likely lead to population extinction. Under any wind farm proposal scenario, over 92% of expected deaths would occur in the core area of the population, further implying inadequate spatial planning and implementation of relevant European legislation with scant regard for governmental obligations to protect key species. On the basis of a sensitivity map we derive a spatially explicit solution that could meet the national target of wind harnessing with a minimum conservation cost of less than 1% population loss providing that the population mortality (5.2%) caused by the operating wind farms in the core area would be totally mitigated. Under other scenarios, the vulture population would probably be at serious risk of extinction. Our 'win-win' approach is appropriate to other potential conflicts where wind farms may cumulatively threaten wildlife populations.
[Mh] Termos MeSH primário: Conservação dos Recursos Naturais/métodos
Fontes Geradoras de Energia
Falconiformes
Modelos Teóricos
Vento
[Mh] Termos MeSH secundário: Animais
Mudança Climática
Europa Oriental
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170224
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0172685


  9 / 4025 MEDLINE  
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[PMID]:28225426
[Au] Autor:Committee on Genetics
[Ti] Título:Committee Opinion No. 691: Carrier Screening for Genetic Conditions.
[So] Source:Obstet Gynecol;129(3):e41-e55, 2017 03.
[Is] ISSN:1873-233X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Carrier screening is a term used to describe genetic testing that is performed on an individual who does not have any overt phenotype for a genetic disorder but may have one variant allele within a gene(s) associated with a diagnosis. Information about carrier screening should be provided to every pregnant woman. Carrier screening and counseling ideally should be performed before pregnancy because this enables couples to learn about their reproductive risk and consider the most complete range of reproductive options. A patient may decline any or all screening. When an individual is found to be a carrier for a genetic condition, his or her relatives are at risk of carrying the same mutation. The patient should be encouraged to inform his or her relatives of the risk and the availability of carrier screening. If an individual is found to be a carrier for a specific condition, the patient's reproductive partner should be offered testing in order to receive informed genetic counseling about potential reproductive outcomes. If both partners are found to be carriers of a genetic condition, genetic counseling should be offered. What follows is a detailed discussion of some of the more common genetic conditions for which carrier screening is recommended in at least some segments of the population.
[Mh] Termos MeSH primário: Triagem de Portadores Genéticos
Aconselhamento Genético
Testes Genéticos/normas
Judeus/genética
[Mh] Termos MeSH secundário: Fibrose Cística/genética
Revelação
Europa Oriental/etnologia
Feminino
Síndrome do Cromossomo X Frágil/genética
Hemoglobinopatias/genética
Seres Humanos
Aceitação pelo Paciente de Cuidados de Saúde
Educação de Pacientes como Assunto
Gravidez
Medição de Risco
Doença de Tay-Sachs/genética
[Pt] Tipo de publicação:JOURNAL ARTICLE; PRACTICE GUIDELINE
[Em] Mês de entrada:1706
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170223
[St] Status:MEDLINE
[do] DOI:10.1097/AOG.0000000000001952


  10 / 4025 MEDLINE  
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[PMID]:28209653
[Au] Autor:Balabanova Y; Fiebig L; Ignatyeva O; Riekstina V; Danilovits M; Jaama K; Davidaviciene E; Radiulyte B; Popa CM; Nikolayevskyy V; Drobniewski F
[Ad] Endereço:Blizard Institute, Queen Mary, University of London, London, UK.
[Ti] Título:Multidrug-resistant TB in Eastern region of the EU: is the shorter regimen an exception or a rule?
[So] Source:Thorax;72(9):850-852, 2017 Sep.
[Is] ISSN:1468-3296
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:WHO recently recommended the use of a shorter multidrug-resistant TB (MDR-TB) regimen under programmatic conditions. We assessed eligibility for this regimen in a cohort of 737 adult patients with MDR-TB from Latvia, Lithuania, Estonia and Bucharest city recruited in 2007 and 2009. Only 4.2% of the patients were eligible for this regimen. Ethambutol (64%), pyrazinamide resistance (58%) and previous exposure to second-line TB drugs were major reasons for non-eligibility. High-level resistance to isoniazid is expected due to widespread prevalence of mutations. In Eastern Europe, the use of the shorter regimen might be an exception rather than a rule.
[Mh] Termos MeSH primário: Antituberculosos/administração & dosagem
Tuberculose Resistente a Múltiplos Medicamentos/tratamento farmacológico
[Mh] Termos MeSH secundário: Adulto
Esquema de Medicação
Farmacorresistência Bacteriana Múltipla
Quimioterapia Combinada
Europa Oriental
Feminino
Seres Humanos
Masculino
Meia-Idade
[Pt] Tipo de publicação:LETTER; MULTICENTER STUDY
[Nm] Nome de substância:
0 (Antitubercular Agents)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170912
[Lr] Data última revisão:
170912
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170218
[St] Status:MEDLINE
[do] DOI:10.1136/thoraxjnl-2016-209841



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