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[PMID]:28837874
[Au] Autor:Halecki W; Klatka S
[Ad] Endereço:Department of Land Reclamation and Environmental Development, University of Agriculture, Al. Mickiewicza 24/28, 30-059 Kraków, Poland. Electronic address: wiktor.halecki@urk.edu.pl.
[Ti] Título:Long term growth of crop plants on experimental plots created among slag heaps.
[So] Source:Ecotoxicol Environ Saf;147:86-92, 2018 Jan.
[Is] ISSN:1090-2414
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Suppression of plant growth is a common problem in post-mining reclaimed areas, as coarse texture of soils may increase nitrate leaching. Assessing feasibility of using solid waste (precipitated solid matter) produced by water and sewage treatment processes in field conditions is very important in mine soil reclamation. Our work investigated the possibility of plant growth in a degraded site covered with sewage-derived sludge material. A test area (21m × 18m) was established on a mine soil heap. Experimental plant species included Camelina sativa, Helianthus annuus, Festuca rubra, Miscanthus giganteus, Amaranthus cruentus, Brassica napus, Melilotus albus, Beta vulgaris, and Zea mays. ANOVA showed sufficient water content and acceptable physical properties of the soil in each year and layer in a multi-year period, indicating that these species were suitable for phytoremediation purposes. Results of trace elements assays indicated low degree of contamination caused by Carbocrash waste material and low potential ecological risk for all plant species. Detrended correspondence analysis revealed that total porosity and capillary porosity were the most important variables for the biosolids among all water content related properties. Overall, crop plants were found useful on heavily degraded land and the soil benefited from their presence. An addition of Carbocrash substrate to mine soil improved the initial stage of soil reclamation and accelerated plant growth. The use of this substrate in phytoremediation helped to balance the content of nutrients, promoted plant growth, and increased plant tolerance to salinity. Sewage sludge-amended biosolids may be applied directly to agricultural soil, not only in experimental conditions.
[Mh] Termos MeSH primário: Produtos Agrícolas/crescimento & desenvolvimento
Mineração
Esgotos/química
Poluentes do Solo/análise
Solo/química
Resíduos Sólidos/análise
[Mh] Termos MeSH secundário: Biodegradação Ambiental
Biomassa
Polônia
Porosidade
Propriedades de Superfície
Fatores de Tempo
Oligoelementos/análise
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Sewage); 0 (Soil); 0 (Soil Pollutants); 0 (Solid Waste); 0 (Trace Elements)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180309
[Lr] Data última revisão:
180309
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170825
[St] Status:MEDLINE


  2 / 41718 MEDLINE  
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[PMID]:29280369
[Au] Autor:Barbarska O; Zielinska M; Pawlus B; Wesolowska A
[Ad] Endereço:Laboratory of Human Milk and Lactation Research, Regional Human Milk Bank in Holy Family Hospital, Department of Neonatology, Medical University of Warsaw, Poland
[Ti] Título:Characteristics of the regional human milk bank in Poland - donors, recipients and nutritional value of human milk
[So] Source:Rocz Panstw Zakl Hig;68(4):395-400, 2017.
[Is] ISSN:0035-7715
[Cp] País de publicação:Poland
[La] Idioma:eng
[Ab] Resumo:Background: In case of shortage of breast milk despite proper lactation care or the poor state of the mother's health, breast milk from human milk bank is recommended for feeding preterm infants Objective: This study retrospectively evaluated the first year of the operation of the Regional Human Milk Bank Material and methods: Data concerning donors was collected in the human milk bank during the cooperation. The clinical characteristics of the recipients was made on the basis of medical documentation from the Holy Family Hospital in Warsaw, Poland. Analysis of nutritional value was performed with the human milk analyzer (MIRIS AB) Results: In the first year of activity, 45 voluntary donors established cooperation, donating from 650 to 32030 ml of human milk. The content of nutrients in milk provided by donors was variable - protein 0.4-1.5 g / 100 ml, fat 1.1-7.4 g / 100 ml, carbohydrates 6.3-7.9 g / 100 ml. The average length of using donated human milk was 4 days and the average volume of milk for one infant was 282 ml Conclusions: The donor profiles have a significant impact on the milk composition form HMB. The nutritional value can be improved by recruitment donors from mothers that gave birth prematurely and by beginning donation at earlier stages of lactation as soon as lactation is stabilized. In case of shortage of mothers own milk the immediate implementation of donors milk as a short-term support can significantly reduce the food intolerance incidence in the group of prematurely born infants
[Mh] Termos MeSH primário: Bancos de Leite
Leite Humano/química
Valor Nutritivo
[Mh] Termos MeSH secundário: Carboidratos da Dieta/análise
Gorduras na Dieta/análise
Proteínas na Dieta/análise
Feminino
Seres Humanos
Fenômenos Fisiológicos da Nutrição do Lactente
Recém-Nascido
Polônia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Dietary Carbohydrates); 0 (Dietary Fats); 0 (Dietary Proteins)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171228
[St] Status:MEDLINE


  3 / 41718 MEDLINE  
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[PMID]:29278907
[Au] Autor:Chojecka A; Tarka P; Kierzkowska A; Nitsch-Osuch A; Kanecki K
[Ad] Endereço:National Institute of Public Health ­ National Institute of Hygiene, Department of Bacteriology, Warsaw, Poland
[Ti] Título:Neutralization efficiency of alcohol based products used for rapid hand disinfection
[So] Source:Rocz Panstw Zakl Hig;68(4):389-394, 2017.
[Is] ISSN:0035-7715
[Cp] País de publicação:Poland
[La] Idioma:eng
[Ab] Resumo:Background: Alcohols are the most commonly used active substances in preparations for quick hand disinfection. They should be bactericidal in very short contact time. PN-EN 13727 + A2: 2015-12 standard, for testing hygienic and surgical handrub disinfection preparations, provides mandatory test conditions of disinfectants in contact times with the range of 30 s to 60 s (hygienic handrub disinfection) and 60 s to 5 min (surgical handrub disinfection). A short contact times for hand hygiene products require a short time of neutralization process. For contact times less than or equal to 10 minutes, the estimated neutralization time is 10 s ± 1 s. Neutralization is a process that abolishes the action of disinfectants. Correct application of this process allows for proper use of disinfectants in practice and its biocidal effect. Objectives. Verification of the effectiveness of 10-second neutralization time of alcohol based preparations for hygienic handrub disinfection Materials and Method: Neutralization of two products with different ethanol content (89% and 70%) for hygienic handrub disinfection according to PN-EN 13727 + A2: 2015-12 was investigated. The effectiveness of the neutralizer was assessed by determining toxicity of neutralizer, activity of residual effects of the tested products and their derivatives produced during neutralization (10 s) for test organisms (Staphylococcus aureus ATCC 6538; Pseudomonas aeruginosa ATCC 15442; Enterococcus hirae ATCC 10541; Escherichia coli K12 NCTC 10538) Results: The 10-second neutralization time was sufficient to eliminate the residual activity of products for hygienic handrub disinfection with differentiated ethanol concentration. The neutralizer used did not show toxicity to bacteria and did not produce toxic products with tested preparations after neutralization Conclusions: Conclusions. The use of 10-second neutralization time allows in a precise way designate the contact times for hygienic handrub disinfection products
[Mh] Termos MeSH primário: Antibacterianos/farmacologia
Bactérias/efeitos dos fármacos
Etanol/farmacologia
Desinfecção das Mãos
Higiene das Mãos/métodos
Higienizadores de Mão/farmacologia
[Mh] Termos MeSH secundário: Bactérias/crescimento & desenvolvimento
Contagem de Colônia Microbiana
Desinfecção/métodos
Seres Humanos
Testes de Neutralização/métodos
Polônia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Bacterial Agents); 0 (Hand Sanitizers); 3K9958V90M (Ethanol)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171228
[St] Status:MEDLINE


  4 / 41718 MEDLINE  
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[PMID]:29265787
[Au] Autor:Bzikowska A; Czerwonogrodzka-Senczyna A; Riahi A; Weker H
[Ad] Endereço:Warsaw Medical University, Faculty of Health Science, Department of Clinical Dietetics, Warsaw, Poland
[Ti] Título:Nutritional value of daily food rations of overweight and normal weight pregnant women
[So] Source:Rocz Panstw Zakl Hig;68(4):375-379, 2017.
[Is] ISSN:0035-7715
[Cp] País de publicação:Poland
[La] Idioma:eng
[Ab] Resumo:Background: Adequate nutrition and nutritional status during pregnancy are essential for mother's health and foetus development. Due to increased demands, pregnant women are vulnerable to inadequate nutritional status and paradoxically it may also affect overweight women Objective: The aim of the study was to evaluate energy and nutrients intake in the group of pregnant women in relation to nutritional standards and pre-pregnancy BMI Material and methods: The study included 90 women, during the third trimester of pregnancy, recruited from Warsaw antenatal classes. The anthropometric data gathered in the research were used to calculate BMI value before pregnancy. Pre-pregnancy BMI was categorised as: normal weight (BMI=18.5-24.9 kg/m2, n=47) and overweight (BMI ≥25.0 kg/m2, n=43). The assessment of women's nutrition was based on 3-days dietary record. Due to heterogeneous variances, differences between groups were assessed using Mann Whitney U test, p<0.05 was considered as significant Results: The mean intake of energy, protein, fat and carbohydrates in the overweight women were significantly higher than in healthy weight women (p<0.05). Most of the healthy weight women did not reach EAR standard for vitamin D (79.5%), whereas in overweight group it was 41.3% Conclusions: Despite the fact that intakes of energy and all nutrients were higher in overweight women than in normal weight ones, we observed that women in both groups had risk of insufficient supply of energy, iodine, potassium and vitamin D. For this reason, accurate nutritional assessment should be an integral part of obstetric care
[Mh] Termos MeSH primário: Dieta
Estado Nutricional
Valor Nutritivo
Terceiro Trimestre da Gravidez
Fenômenos Fisiológicos da Nutrição Pré-Natal
[Mh] Termos MeSH secundário: Índice de Massa Corporal
Registros de Dieta
Feminino
Seres Humanos
Peso Corporal Ideal
Avaliação Nutricional
Sobrepeso
Polônia
Gravidez
Cuidado Pré-Natal
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171222
[St] Status:MEDLINE


  5 / 41718 MEDLINE  
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[PMID]:29265781
[Au] Autor:Czekajlo A; Rózanska D; Mandecka A; Konikowska K; Madalinska M; Regulska-Ilow B
[Ad] Endereço:Wroclaw Medical University, Faculty of Health Sciences, Department of Dietetics, Wroclaw, Poland
[Ti] Título:Comparison of nutritional value of "fruit and vegetables" and "western" dietary patterns identified in a group of cancer patients
[So] Source:Rocz Panstw Zakl Hig;68(4):365-373, 2017.
[Is] ISSN:0035-7715
[Cp] País de publicação:Poland
[La] Idioma:eng
[Ab] Resumo:Background: Dietary patterns (DPs) are defined as the amounts, types and combinations of various food products in habitual diets and the frequency of their consumption. Dietary pattern analysis is usually performed in order to assess the combined effect of consumed food products on health Objective: The aim of the study was to assess and compare the nutritional value of dietary patterns identified in a group of patients staying on the oncological ward Material and methods: The study group consisted of 100 patients (51 women and 49 men) aged 19-83 years. Dietary intake was assessed using a food frequency questionnaire (FFQ) validated for the population of Lower Silesian Voivodeship Results: Factor analysis identified two main dietary patterns explaining 25.6% of variance. The "fruit and vegetables" DP consisted of vegetables, fruits, juices, unrefined grains and nuts, seeds and raisins. Instead, the "Western" DP was characterized by the consumption of high-fat and processed meat and poultry, fried fish, refined grains, honey and sugar, fats, sweets, beverages and chips. While higher scores for "fruit and vegetables" pattern were associated with increased intake of dietary fiber, antioxidant vitamins, folic acid and decreased glycemic load per 1000 kcal and sodium intake, for "Western" pattern observed relationships were opposite. Women were more likely to have higher factor scores for "fruit and vegetables" DP and lower factor scores for "Western" DP than men Conclusions: Dietary patterns identified in the study group differed in terms of nutritional value, in spite of similar macronutrient content in the diet. "Western" DP was characterized by lower nutritional value than "fruit and vegetables" dietary pattern.
[Mh] Termos MeSH primário: Dieta Ocidental
Comportamento Alimentar
Frutas
Neoplasias/terapia
Valor Nutritivo
Verduras
[Mh] Termos MeSH secundário: Adulto
Idoso
Idoso de 80 Anos ou mais
Ingestão de Energia
Análise Fatorial
Feminino
Seres Humanos
Masculino
Meia-Idade
Avaliação Nutricional
Polônia
Fatores Sexuais
Inquéritos e Questionários
Adulto Jovem
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171222
[St] Status:MEDLINE


  6 / 41718 MEDLINE  
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[PMID]:29264911
[Au] Autor:Mania M; Rebeniak M; Szynal T; Starska K; Wojciechowska-Mazurek M; Postupolski J
[Ad] Endereço:National Institute of Public Health-National Institute of Hygiene, Department of Food Safety, Warsaw, Poland
[Ti] Título:Exposure assessment of the population in Poland to the toxic effects of arsenic compounds present in rice and rice based products
[So] Source:Rocz Panstw Zakl Hig;68(4):339-346, 2017.
[Is] ISSN:0035-7715
[Cp] País de publicação:Poland
[La] Idioma:eng
[Ab] Resumo:Background: Rice is a staple food for many people in the world and an important ingredient for production of food for infants and young children. According to European Food Safety Authority (EFSA), cereals, primarily rice and rice products, are an important source of human exposure to inorganic arsenic, which has been classified by the International Agency for Research on Cancer (IARC) as group I carcinogen. Arsenic is present in rice and rice products mainly as an inorganic form being more toxic than organic compounds Objectives: The aim of the study was to determine the total and inorganic arsenic content in rice, rice-based products including food for infants and young children available on the market in Poland and thus to estimate consumer exposure to inorganic arsenic from these groups of foodstuffs Materials and Methods: A total of 62 samples of rice and rice products from trade, including a group of rice products for infants and young children, were tested. Contents of total and inorganic arsenic were determined by using hydride generation atomic absorption spectrometry (HGAAS), after dry mineralization of samples and reduction of arsenic to arsenic hydride with sodium borohydride. To extract the inorganic arsenic forms, the samples were subjected to hydrolysis in concentrated HCl and then reduced in the presence of hydrobromic acid and hydrazine sulphate after which triple chloroform extractions and triple 1M HCl re-extractions were performed. Exposure of different groups of populations (adults and children), was estimated in relation to the Benchmark Dose Lower Confidence Limit (BMDL05) as set by the Joint FAO/WHO Expert Committee on Food Additives (JECFA) that resulted in a 0.5% increase in lung cancer (3.0 µg/kg body weight (b.w.) per day) Results: Mean content of total and inorganic arsenic in investigated rice samples was 0.12 mg/kg (median: 0.09 mg/kg; 90th percentile 0.22 mg/kg) and 0.04 mg/kg (median: 0.03 mg/kg, 90th percentile 0.07 mg/kg). Brown rice was found to be more highly contaminated with both total and inorganic arsenic than white rice. Mean contamination of brown rice with total arsenic and inorganic arsenic was: 0.18 mg/kg (median: 0.12 mg/kg, 90th percentile: 0.32 mg/kg) and 0.05 mg/kg (median: 0.05 mg/kg, 90th percentile: 0.07 mg/kg). In turn for the white rice contamination was lower, mean total arsenic content: 0.10 mg/kg (median: 0.08 mg/kg, 90th percentile: 0.19 mg/kg) and mean inorganic arsenic: 0.03 mg/kg (median: 0.03 mg/kg, 90th percentile: 0.06 mg/kg). Contamination of rice-based products both total and inorganic arsenic was similar to those reported for rice, except rice wafers (mean: 0.24 mg/kg and 0.13 mg/kg). In the group of products for infants and young children obtained results were low ­ mean total arsenic content was 0.06 mg/kg and inorganic arsenic 0.02 mg/kg. The estimated average adult and children's exposure to inorganic arsenic with rice and rice products was less than 1% of the BMDL05. Intake of inorganic arsenic by 12-month-old infants with ricebased products intended for this group of population was at 6% BMDL05 Conclusions: Based on the obtained results, it was found that the content of total and inorganic arsenic in investigated samples of rice and rice products did not pose a health risk even though contamination levels in some individual samples were significant
[Mh] Termos MeSH primário: Arsenicais/análise
Carcinógenos/análise
Exposição Dietética/análise
Contaminação de Alimentos/análise
Oryza/química
[Mh] Termos MeSH secundário: Análise de Alimentos
Inocuidade dos Alimentos
Seres Humanos
Polônia
Medição de Risco
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Arsenicals); 0 (Carcinogens)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171222
[St] Status:MEDLINE


  7 / 41718 MEDLINE  
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[PMID]:29264907
[Au] Autor:Cwiek-Ludwicka K; Ludwicki JK
[Ad] Endereço:National Institute of Public Health - National Institute of Hygiene, Warsaw, Poland
[Ti] Título:Nanomaterials in food contact materials; considerations for risk assessment
[So] Source:Rocz Panstw Zakl Hig;68(4):321-329, 2017.
[Is] ISSN:0035-7715
[Cp] País de publicação:Poland
[La] Idioma:eng
[Ab] Resumo:Nanotechnology applications in the food industry, including food contact materials, offer many potential benefits for consumers and manufacturers alike. The article discusses the migration of nanoparticles from food contact materials and the possible health risks associated with in the context of insufficient knowledge of the potential exposure to nanomaterial. The importance of gaps in the general knowledge on the behaviour and biological interactions of nanomaterials in biological systems becomes crucial for risk assessment. The article also discussed numerous doubts concerning the measurements of biological reactions in animal tests and the need for new approaches in the interpretation of data from nanoparticles studies in vivo. The article underlines the need to develop predictive and validated toxicological tests that can be used to screen for potential hazards, and also to develop new methodology for measuring nanoparticles in biological matrices to assess human exposure. Further studies should focus on understanding the mechanisms of action. Nanoparticles exhibit chemical and physical properties that significantly differ from those substances at a large size. Different properties of nanoparticles may lead to different toxicological properties. From that reason nanoparticles, in each case, are individually assessed by the European Food Standard Agency (EFSA) in terms of health risk before the European Commission authorizes them to be used in food contact materials.
[Mh] Termos MeSH primário: Exposição Dietética/normas
Contaminação de Alimentos/prevenção & controle
Embalagem de Alimentos/normas
Nanoestruturas/normas
[Mh] Termos MeSH secundário: Segurança de Produtos ao Consumidor
Exposição Dietética/análise
Contaminação de Alimentos/análise
Seres Humanos
Nanoestruturas/efeitos adversos
Nanoestruturas/análise
Tamanho da Partícula
Polônia
Medição de Risco
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171222
[St] Status:MEDLINE


  8 / 41718 MEDLINE  
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[PMID]:29203752
[Au] Autor:Gruber-Bzura BM
[Ad] Endereço:Zaklad Biochemii I Biofarmaceutykow; Narodowy Instytut Lekow, Warszawa Polska.
[Ti] Título:[Cytotoxicity in vitro as the principal parameter for evaluation of biocompatibility of medical devices].
[So] Source:Wiad Lek;70(5):977-981, 2017.
[Is] ISSN:0043-5147
[Cp] País de publicação:Poland
[La] Idioma:pol
[Ab] Resumo:According to the Polish Ministry of Health decree, the medical devices and all raw materials used for their manufacturing are in force to be compatible with biological tissues, cells and body fluids regarding its clinical use. It is defined as biocompatibility. The scope of the methods proposed in the norm PN-EN ISO 10993-1 makes possible to get full preclinical characteristics of the medical device and allows to form the opinion about safety of it to the patients after its marketing. The test directed as the principal to make, independently on characteristics, kind, contact duration and clinical use of the device is cytotoxicity in vitro. This test defines the impact of the device on the cells through microscopic evaluation or through activities of the enzymes specific for living cells. Toxicity of the material to the cells may be reflected in: change of single cells or whole cell culture morphology, change of cellular metabolic activity, DNA damage or disadvantage of cell proliferation. Biocompatibility of the medical devices is one of the main elements considered in a risk management process at the stage of designing and manufacturing as well of the raw materials as the final product and the critical point in this matter is sterilization.
[Mh] Termos MeSH primário: Materiais Biocompatíveis/normas
Equipamentos e Provisões/normas
Teste de Materiais/normas
Testes de Toxicidade/normas
[Mh] Termos MeSH secundário: Seres Humanos
Legislação de Dispositivos Médicos
Polônia
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Biocompatible Materials)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171206
[St] Status:MEDLINE


  9 / 41718 MEDLINE  
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[PMID]:29203733
[Au] Autor:Derkowski T; Kosinski S; Podsiadlo P; Sanak T; Salapa K; Wejnarski A; Galazkowski R; Darocha T
[Ad] Endereço:Lotnicze Pogotowie Ratunkowe, Warszawa, Polska.
[Ti] Título:[Assessment of knowledge about hypothermia among the medical personnel of polish medical air rescue].
[So] Source:Wiad Lek;70(5):875-880, 2017.
[Is] ISSN:0043-5147
[Cp] País de publicação:Poland
[La] Idioma:pol
[Ab] Resumo:Polish Medical Air Rescue is tasked to deal with the most serious incidents associated with life threatening situations, in multiple circumstances. As a consequence, medical personnel have to meet high standards of education and show a continuous theoretical and practical development of the skills which are necessary during medical treatment. Thanks to the introduction of ECMO treatment for accidental hypothermia patients, new clinical and operational possibilities have arisen, so more patients can be saved with a very good neurological outcome. AIM: To analyze the data on hypothermia collected by the personnel of Polish Medical Air Rescue and to assess the e-learning platform as an educational tool. MATERIALS AND METHODS: 123 persons were involved. The subject of analysis were the e-learning platform results of the Polish Medical Air Rescue medical personnel. The e-learning consisted of a pre-test, 8 lessons followed by MCQ's (multi choice questions) and a post-test. RESULTS AND CONCLUSIONS: We could not prove a statistically significant difference in the knowledge about hypothermia between doctors and other medical professionals. Post-traumatic hypothermia and associated coagulation disturbances are two important topics requiring particular focus during the design of further educational and training projects. As a consequence of the training, both groups significantly improved their knowledge: i.e. a statistically significant improvement of knowledge about hypothermia between pre-test and post-test results in both groups was shown. The hypothermia e-learning platform for medical personnel is an effective educational tool.
[Mh] Termos MeSH primário: Resgate Aéreo
Atitude do Pessoal de Saúde
Serviço Hospitalar de Emergência/normas
Conhecimentos, Atitudes e Prática em Saúde
Hipotermia/terapia
[Mh] Termos MeSH secundário: Adulto
Serviços Médicos de Emergência
Feminino
Seres Humanos
Masculino
Polônia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171206
[St] Status:MEDLINE


  10 / 41718 MEDLINE  
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[PMID]:28453842
[Au] Autor:Lipowski D; Popiel M; Perlejewski K; Nakamura S; Bukowska-Osko I; Rzadkiewicz E; Dzieciatkowski T; Milecka A; Wenski W; Ciszek M; Debska-Slizien A; Ignacak E; Cortes KC; Pawelczyk A; Horban A; Radkowski M; Laskus T
[Ad] Endereço:Department of Infectious Diseases, Warsaw Medical University, Warsaw, Poland.
[Ti] Título:A Cluster of Fatal Tick-borne Encephalitis Virus Infection in Organ Transplant Setting.
[So] Source:J Infect Dis;215(6):896-901, 2017 03 15.
[Is] ISSN:1537-6613
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Background: Tick-borne encephalitis virus (TBEV) infection has become a major health problem in Europe and is currently a common cause of viral brain infection in many countries. Encephalitis in transplant recipients, althrough rare, is becoming a recognized complication. Our study provides the first description of transmission of TBEV through transplantation of solid organs. Methods: Three patients who received solid organ transplants from a single donor (2 received kidney, and 1 received liver) developed encephalitis 17-49 days after transplantation and subsequently died. Blood and autopsy tissue samples were tested by next-generation sequencing (NGS) and reverse transcription polymerase chain reaction (RT-PCR). Results: All 3 recipients were first analyzed in autopsy brain tissue samples and/or cerebrospinal fluid by NGS, which yielded 24-52 million sequences per sample and 9-988 matched TBEV sequences in each patient. The presence of TBEV was confirmed by RT-PCR in all recipients and in the donor, and direct sequencing of amplification products corroborated the presence of the same viral strain. Conclusions: We demonstrated transmission of TBEV by transplantation of solid organs. In such a setting, TBEV infection may be fatal, probably due to pharmacological immunosuppression. Organ donors should be screened for TBEV when coming from or visiting endemic areas.
[Mh] Termos MeSH primário: Encéfalo/virologia
Vírus da Encefalite Transmitidos por Carrapatos/isolamento & purificação
Encefalite Transmitida por Carrapatos/transmissão
Transplante de Órgãos/efeitos adversos
Doadores de Tecidos
[Mh] Termos MeSH secundário: Adulto
Autopsia
Seleção do Doador
Encefalite Transmitida por Carrapatos/etiologia
Evolução Fatal
Seres Humanos
Masculino
Meia-Idade
Polônia
Complicações Pós-Operatórias/etiologia
RNA Viral/sangue
Análise de Sequência de RNA
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (RNA, Viral)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170429
[St] Status:MEDLINE
[do] DOI:10.1093/infdis/jix040



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