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  1 / 99 MEDLINE  
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PMID:27774794
Autor:Seay JS; Mandigo M; Kish J; Menard J; Marsh S; Kobetz E
Endereço:a Miller School of Medicine , University of Miami , Miami , FL , USA.
Título:Intravaginal practices are associated with greater odds of high-risk HPV infection in Haitian women.
Fonte:Ethn Health; 22(3):257-265, 2017 Jun.
ISSN:1465-3419
País de publicação:England
Idioma:eng
Resumo:OBJECTIVE: Haitian women have the highest incidence of cervical cancer within the Western hemisphere. Intravaginal hygiene practices have been linked with human papilloma virus (HPV) infection and cervical dysplasia. These practices, known as 'twalet deba' in Haitian Creole, are common among Haitian women and are performed with various natural and synthetic agents. As part of a community-based participatory research initiative aimed at reducing cervical cancer disparities in rural Haiti, we explored the use of intravaginal agents and their associations with high-risk HPV infection. DESIGN: Community Health Workers recruited 416 women for cervical self-sampling from two neighborhoods within Thomonde, Haiti. Participants were interviewed regarding intravaginal hygiene practices and completed a cervical self-sampling procedure. Cervical samples were analyzed for the presence of high-risk HPV infection. Associations between each intravaginal agent and high-risk HPV infection were examined via univariate logistic regression analyses, as well as via multivariate analyses controlling for sociodemographic factors and concurrent agent use. RESULTS: Nearly all women (97.1%) performed twalet deba, using a variety of herbal and commercially produced intravaginal agents. Approximately 11% of the participants tested positive for high-risk HPV. Pigeon pea and lime juice were the only agents found to be associated with high-risk HPV in the univariate analyses, with women who used these agents being approximately twice as likely to have high-risk HPV as those who did not. Only pigeon pea remained significantly associated with high-risk HPV after controlling for sociodemographic factors and concurrent agent use. CONCLUSION: Two agents, pigeon pea and lime juice, may contribute to risk for HPV infection in this population. Results suggest that in addition to cervical cancer screening interventions, future preventive initiatives should focus on minimizing risk by advocating for the use of less-toxic twalet deba alternatives.
Tipo de publicação: JOURNAL ARTICLE
Nome de substância:0 (Alum Compounds); 0 (Plant Preparations); 0 (Soaps); 00OT1QX5U4 (Potassium Permanganate); 34S289N54E (aluminum sulfate)


  2 / 99 MEDLINE  
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PMID:27122477
Autor:Hithamani G; Srinivasan K
Endereço:Department of Biochemistry and Nutrition, CSIR - Central Food Technological Research, Mysore, 570 020, India.
Título:Bioaccessibility of polyphenols from selected cereal grains and legumes as influenced by food acidulants.
Fonte:J Sci Food Agric; 97(2):621-628, 2017 Jan.
ISSN:1097-0010
País de publicação:England
Idioma:eng
Resumo:BACKGROUND: Polyphenols in food are valued for their health-beneficial influences. Food acidulants lime juice and amchur used in Indian cookery were evaluated for their influence on polyphenol bioaccessibility from food grains. RESULTS: Lime juice increased bioaccessible flavonoids by 25% in roasted finger millet, while there was no change in total bioaccessible polyphenols in pressure-cooked, open-pan-boiled and roasted finger millet in the presence of food acidulants. Addition of amchur to pressure-cooked and microwave-heated pearl millet increased bioaccessible flavonoids by 30 and 53% respectively, while lime juice increased them by 46% in pressure-cooked pearl millet. Increased bioaccessibility of specific phenolic acids from finger millet and pearl millet was observed upon addition of these food acidulants. The presence of either lime juice or amchur increased bioaccessible flavonoids from both legumes studied. Addition of lime juice and amchur, however, exerted a negative effect on the bioaccessibility of several phenolic compounds from food grains in native state and under certain processing conditions. CONCLUSION: Thus food acidulants lime juice and amchur had a significant influence on the bioaccessibility of health-beneficial phenolic compounds from food grains. Use of food acidulants in food preparations could be a strategy to enhance the bioavailability of polyphenols, especially flavonoids from grains. © 2016 Society of Chemical Industry.
Tipo de publicação: COMPARATIVE STUDY; JOURNAL ARTICLE
Nome de substância:0 (Antioxidants); 0 (Flavonoids); 0 (Flavoring Agents); 0 (Polyphenols)


  3 / 99 MEDLINE  
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PMID:27272092
Autor:Mathieu RJ; Cheraghi N; Russo MA
Título:Resident Rounds: Part III - Case Report: Betel Quid Induced Irritant Contact Dermatitis of the Hand.
Fonte:J Drugs Dermatol; 15(6):789-90, 2016 Jun 01.
ISSN:1545-9616
País de publicação:United States
Idioma:eng
Resumo:Betel quid is a drug used in Far East Asia, India, and the South Pacific. The habit of betel quid chewing is widely reported to cause oral cancer and tooth and gum disease. However, skin disease due to betel quid use is underreported. We report a case of irritant contact dermatitis to betel quid components in a 35-year-old male betel quid user who presented for evaluation of a persistent rash on his fingertips.
Tipo de publicação: CASE REPORTS; JOURNAL ARTICLE


  4 / 99 MEDLINE  
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PMID:26988490
Autor:Xu JJ; Yang R; Ye LH; Cao J; Cao W; Hu SS; Peng LQ
Endereço:College of Material Chemistry and Chemical Engineering, Hangzhou Normal University, Hangzhou 310036, China.
Título:Application of ionic liquids for elution of bioactive flavonoid glycosides from lime fruit by miniaturized matrix solid-phase dispersion.
Fonte:Food Chem; 204:167-75, 2016 Aug 01.
ISSN:0308-8146
País de publicação:England
Idioma:eng
Resumo:In this work, two flavonoid glycosides (neohesperidin and naringin) in lime fruit were effectively extracted by miniaturized matrix solid phase dispersion (MSPD), followed by ultra-performance liquid chromatography-ultraviolet detection. The best results were obtained using Florisil (150mg) as the sorbent and 1-butyl-3-methylimidazolium tetrafluoroborate (0.4mL, 250mM) as the elution solvent. This work represents the first attempt of using ionic liquids as a green eluent for extraction of the investigated compounds in miniaturized MSPD. Compared with the conventional methods, the proposed method is advantageous due to improved enrichment factor and reduced reagent consumption. A good linearity was observed with r(2) values (>0.998). Meanwhile, the method gave acceptable recoveries (90.16-96.47%) for the determination of flavonoids in plant samples. The limits of detection of the two analytes ranged between 4.08 and 5.04µg/g. The results showed that the optimized method has a great potential for sample preparation in routine analysis of complex plant samples.
Tipo de publicação: JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
Nome de substância:0 (1-butyl-3-methylimidazolium tetrafluoroborate); 0 (Flavanones); 0 (Imidazoles); 0 (Ionic Liquids); 0 (Solvents); E750O06Y6O (Hesperidin); N7TD9J649B (naringin); OA5C88H3L0 (neohesperidin)


  5 / 99 MEDLINE  
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PMID:26944784
Autor:Curk F; Ollitrault F; Garcia-Lor A; Luro F; Navarro L; Ollitrault P
Endereço:Unité Mixte de Recherche Amélioration Génétique et Adaptation des Plantes (UMR Agap), Institut National de la Recherche Agronomique (INRA), F-20230 San Giuliano, France, Centro de Protección Vegetal y Biotecnología, Instituto Valenciano de Investigaciones Agrarias (IVIA), 46113 Moncada (Valencia), S
Título:Phylogenetic origin of limes and lemons revealed by cytoplasmic and nuclear markers.
Fonte:Ann Bot; 117(4):565-83, 2016 Apr.
ISSN:1095-8290
País de publicação:England
Idioma:eng
Resumo:BACKGROUND AND AIMS: The origin of limes and lemons has been a source of conflicting taxonomic opinions. Biochemical studies, numerical taxonomy and recent molecular studies suggested that cultivated Citrus species result from interspecific hybridization between four basic taxa (C. reticulata,C. maxima,C. medica and C. micrantha). However, the origin of most lemons and limes remains controversial or unknown. The aim of this study was to perform extended analyses of the diversity, genetic structure and origin of limes and lemons. METHODS: The study was based on 133 Citrus accessions. It combined maternal phylogeny studies based on mitochondrial and chloroplastic markers, and nuclear structure analysis based on the evaluation of ploidy level and the use of 123 markers, including 73 basic taxa diagnostic single nucleotide polymorphism (SNP) and indel markers. KEY RESULTS: The lime and lemon horticultural group appears to be highly polymorphic, with diploid, triploid and tetraploid varieties, and to result from many independent reticulation events which defined the sub-groups. Maternal phylogeny involves four cytoplasmic types out of the six encountered in the Citrus genus. All lime and lemon accessions were highly heterozygous, with interspecific admixture of two, three and even the four ancestral taxa genomes. Molecular polymorphism between varieties of the same sub-group was very low. CONCLUSIONS: Citrus medica contributed to all limes and lemons and was the direct male parent for the main sub-groups in combination with C. micrantha or close papeda species (for C. aurata, C. excelsa, C. macrophylla and C. aurantifolia--'Mexican' lime types of Tanaka's taxa), C. reticulata(for C. limonia, C. karna and C. jambhiri varieties of Tanaka's taxa, including popular citrus rootstocks such as 'Rangpur' lime, 'Volkamer' and 'Rough' lemons), C. aurantium (for C. limetta and C. limon--yellow lemon types--varieties of Tanaka's taxa) or the C. maxima × C. reticulate hybrid (for C. limettioides--'Palestine sweet' lime types--and C. meyeri). Among triploid limes, C. latifolia accessions ('Tahiti' and 'Persian' lime types) result from the fertilization of a haploid ovule of C. limon by a diploid gamete of C. aurantifolia, while C. aurantifolia triploid accessions ('Tanepao' lime types and 'Madagascar' lemon) probably result from an interspecific backcross (a diploid ovule of C. aurantifolia fertilized by C. medica). As limes and lemons were vegetatively propagated (apomixis, horticultural practices) the intra-sub-group phenotypic diversity results from asexual variations.
Tipo de publicação: JOURNAL ARTICLE
Nome de substância:0 (Genetic Markers)


  6 / 99 MEDLINE  
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PMID:26803192
Autor:Friedman BT; Harper R; Glucksberg A; Strote J
Endereço:Division of Emergency Medicine, Department of Medicine, University of Washington, Seattle, Washington.
Título:In the Limelight.
Fonte:J Emerg Med; 50(3):504-5, 2016 Mar.
ISSN:0736-4679
País de publicação:United States
Idioma:eng
Tipo de publicação: CASE REPORTS; JOURNAL ARTICLE


  7 / 99 MEDLINE  
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PMID:26408813
Autor:Gholivand MB; Mohammadi-Behzad L; Hosseinkhani H
Endereço:Department of Analytical Chemistry, Faculty of Chemistry, Razi University, 67155 Kermanshah, Iran. Electronic address: mbgholivand2013@gmail.com.
Título:Application of a Cu-chitosan/multiwalled carbon nanotube film-modified electrode for the sensitive determination of rutin.
Fonte:Anal Biochem; 493:35-43, 2016 Jan 15.
ISSN:1096-0309
País de publicação:United States
Idioma:eng
Resumo:A new sensitive electrochemical sensor, a glassy carbon electrode modified with chemically cross-linked copper-complexed chitosan/multiwalled carbon nanotubes (Cu-CS/MWCNT/GCE), for rutin analysis was constructed. Experimental investigations of the influence of several parameters showed that the rutin can effectively accumulate on the surface of the Cu-CS/MWCNT/GCE, which accumulation caused a pair of well-defined redox peaks in the electrochemical signal when measurements were carried out in Britton-Robinson buffer solution (pH 3, 0.04 M). The surface of the Cu-CS/MWCNT/GCE was characterized by field-emission scanning electron microscopy, transmission electron microscopy, and X-ray diffractometry analysis. In a rutin concentration range of 0.05-100 µM and under optimized conditions, a linear relationship between the oxidation peak current of rutin and its concentration was obtained with a detection limit of 0.01 µM. The Cu-CS/MWCNT/GCE showed good selectivity, stability, and reproducibility. Moreover, the sensor was used to determine the presence of rutin in fruits with satisfactory results.
Tipo de publicação: EVALUATION STUDIES; JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
Nome de substância:0 (Nanotubes, Carbon); 5G06TVY3R7 (Rutin); 9012-76-4 (Chitosan)


  8 / 99 MEDLINE  
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PMID:26132073
Autor:Mardi M; Karimi Farsad L; Gharechahi J; Salekdeh GH
Endereço:Department of Systems Biology, Agricultural Biotechnology Research Institute of Iran, Karaj, Tehran, Iran.
Título:In-Depth Transcriptome Sequencing of Mexican Lime Trees Infected with Candidatus Phytoplasma aurantifolia.
Fonte:PLoS One; 10(7):e0130425, 2015.
ISSN:1932-6203
País de publicação:United States
Idioma:eng
Resumo:Witches' broom disease of acid lime greatly affects the production of Mexican lime in Iran. It is caused by a phytoplasma (Candidatus Phytoplasma aurantifolia). However, the molecular mechanisms that underlie phytoplasma pathogenicity and the mode of interactions with host plants are largely unknown. Here, high-throughput transcriptome sequencing was conducted to explore gene expression signatures associated with phytoplasma infection in Mexican lime trees. We assembled 78,185 unique transcript sequences (unigenes) with an average length of 530 nt. Of these, 41,805 (53.4%) were annotated against the NCBI non-redundant (nr) protein database using a BLASTx search (e-value ≤ 1e-5). When the abundances of unigenes in healthy and infected plants were compared, 2,805 transcripts showed significant differences (false discovery rate ≤ 0.001 and log2 ratio ≥ 1.5). These differentially expressed genes (DEGs) were significantly enriched in 43 KEGG metabolic and regulatory pathways. The up-regulated DEGs were mainly categorized into pathways with possible implication in plant-pathogen interaction, including cell wall biogenesis and degradation, sucrose metabolism, secondary metabolism, hormone biosynthesis and signalling, amino acid and lipid metabolism, while down-regulated DEGs were predominantly enriched in ubiquitin proteolysis and oxidative phosphorylation pathways. Our analysis provides novel insight into the molecular pathways that are deregulated during the host-pathogen interaction in Mexican lime trees infected by phytoplasma. The findings can be valuable for unravelling the molecular mechanisms of plant-phytoplasma interactions and can pave the way for engineering lime trees with resistance to witches' broom disease.
Tipo de publicação: JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T


  9 / 99 MEDLINE  
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PMID:26078459
Autor:Mioduszewski M; Beecker J
Endereço:Division of Dermatology, University of Ottawa, Ottawa, Ont. mmioduszewski@toh.on.ca.
Título:Phytophotodermatitis from making sangria: a phototoxic reaction to lime and lemon juice.
Fonte:CMAJ; 187(10):756, 2015 Jul 14.
ISSN:1488-2329
País de publicação:Canada
Idioma:eng
Tipo de publicação: CASE REPORTS; JOURNAL ARTICLE
Nome de substância:0 (Photosensitizing Agents)


  10 / 99 MEDLINE  
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PMID:25955743
Autor:Barrio V; Spring L; Pellman L
Endereço:University of California, San Diego, Rady Children's Hospital, San Diego, CA, USA.
Título:A geometric summertime rash.
Fonte:Am Fam Physician; 91(9):649-50, 2015 May 01.
ISSN:1532-0650
País de publicação:United States
Idioma:eng
Tipo de publicação: CASE REPORTS; JOURNAL ARTICLE
Nome de substância:KTZ7ZCN2EX (Ficusin)



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