Base de dados : MEDLINE
Pesquisa : D02.033.100.291.310 [Categoria DeCS]
Referências encontradas : 46134 [refinar]
Mostrando: 1 .. 10   no formato [Longo]

página 1 de 4614 ir para página                         

  1 / 46134 MEDLINE  
              next record last record
seleciona
para imprimir
Fotocópia
Texto completo
PMID:29200984
Autor:Konishi K; Kimura T; Yuhaku A; Kurihara T; Fujimoto M; Hamaoka T; Sanada K
Endereço:Graduate School of Sport and Health Science, Ritsumeikan University, Kyoto, Shiga Japan.
Título:Mouth rinsing with a carbohydrate solution attenuates exercise-induced decline in executive function.
Fonte:J Int Soc Sports Nutr; 14:45, 2017.
ISSN:1550-2783
País de publicação:United States
Idioma:eng
Resumo:Background: A decline in executive function could have a negative influence on the control of actions in dynamic situations, such as sports activities. Mouth rinsing with a carbohydrate solution could serve as an effective treatment for preserving the executive function in exercise. The purpose of this study was to examine the effects of mouth rinsing with a carbohydrate solution on executive function after sustained moderately high-intensity exercise. Methods: Eight young healthy participants completed 65 min of running at 75% V̇O max with two mouth-rinsing conditions: with a carbohydrate solution (CHO) or with water (CON). Executive function was assessed before and after exercise by using the incongruent task of the Stroop Color and Word Test. The levels of blood glucose; and plasma adrenocorticotropic hormone (ACTH), epinephrine, and norepinephrine (NE) were evaluated. A two-way repeated-measures ANOVA, with condition (CHO and CON) and time (pre-exercise and post-exercise) as factors, was used to examine the main and interaction effects on the outcome measures. Results: The reaction time in the incongruent condition of the Stroop test significantly increased after exercise in CON (pre-exercise 529 ± 45 ms vs. post-exercise 547 ± 60 ms, = 0.029) but not in CHO (pre-exercise 531 ± 54 ms vs. post-exercise 522 ± 80 ms), which resulted in a significant interaction (condition × time) on the reaction time ( = 0.028). The increased reaction time in CON indicates a decline in the executive function, which was attenuated in CHO. Increases in plasma epinephrine and NE levels demonstrated a trend toward attenuation accompanying CHO ( < 0.085), which appeared to be associated with the preservation of executive function. The blood glucose concentration showed neither significant interactions nor main effects of condition. Conclusions: These findings indicate that mouth rinsing with a carbohydrate solution attenuated the decline in executive function induced by sustained moderately high-intensity exercise, and that such attenuation seems to be unrelated to carbohydrate metabolic pathway but rather attributed, in part, to the inhibition of the excessive release of stress hormones.
Tipo de publicação: JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
Nome de substância:0 (Blood Glucose); 0 (Dietary Carbohydrates); 0 (Mouthwashes); 059QF0KO0R (Water); 9002-60-2 (Adrenocorticotropic Hormone); YKH834O4BH (Epinephrine)


  2 / 46134 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
PMID:29424509
Autor:Calderón-Lara SA; Morgan-Ortíz F; Trapero-Morales M; Trapero-Corona IM; Peraza-Garay FJ
Título:[Operative morbidity of the hidrodisección with epinefrina during the surgery for prolapse of pelvic organs].
Título:Morbilidad operatoria de la hidrodisección con epinefrina en la cirugía del prolapso de órganos pélvicos..
Fonte:Ginecol Obstet Mex; 84(8):484-90, 2016 08.
ISSN:0300-9041
País de publicação:Mexico
Idioma:spa
Resumo:Objetive: To assess the effect of the hydrodissection on operative morbidity and operative time in patients undergoing vaginal surgery for pelvic organ prolapse. Material and methods: Experimental, prospective, longitudinal, comparative, randomized study: randomized controlled clinical. Randomly, 44 patients were assigned to receive management hydrodissection with epinephrine (Group 1= 22) or not hydrodissection (Group 2= 22) prior to the start of the surgical procedure. The variables analyzed were operative morbidity (defined as infection, hematoma and surgical postoperative bleeding requiring transfusion) and surgical time required to complete the procedure. Results: The average age was 58.1 years (± 9.3) in the group of hydrodissection and 63.0 years (± 10.6) in the group without hydrodissection (p = .111). The frequency of postoperative complications was similar enters both groups (p> .05) presenting only one case of postoperative hematoma in Group 1 and none in Group 2. The operative bleeding was significantly lower in the hydrodissection group (240.9 ± 111.9 mL) compared with the group of non hydrodissection (324.1 ± 104.9 mL). No significant difference in operative time was found (p = 0.67) compared with 135.5 (± 22.6) minutes in Group 1 and 139.3 (± 32.5) minutes. Conclusion: Hydrodissection with epinephrine compared with non Hydrodissection significantly reduces operative bleeding but no differences in operative morbidity and operative time in patients undergoing vaginal surgery in the management of pelvic organ prolapse.
Tipo de publicação: COMPARATIVE STUDY; JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
Nome de substância:YKH834O4BH (Epinephrine)


  3 / 46134 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
PMID:29288665
Autor:Peoples JN; Taylor DG; Katchman AN; Ebert SN
Endereço:Burnett School of Biomedical Sciences, Division of Metabolic and Cardiovascular Sciences, College of Medicine, University of Central Florida, 6900 Lake Nona Blvd, Orlando, FL 32827, United States.
Título:Intact calcium signaling in adrenergic-deficient embryonic mouse hearts.
Fonte:Biochem Biophys Res Commun; 495(4):2547-2552, 2018 01 22.
ISSN:1090-2104
País de publicação:United States
Idioma:eng
Resumo:Mouse embryos that lack the ability to produce the adrenergic hormones, norepinephrine (NE) and epinephrine (EPI), due to disruption of the dopamine beta-hydroxylase (Dbh ) gene inevitably perish from heart failure during mid-gestation. Since adrenergic stimulation is well-known to enhance calcium signaling in developing as well as adult myocardium, and impairments in calcium signaling are typically associated with heart failure, we hypothesized that adrenergic-deficient embryonic hearts would display deficiencies in cardiac calcium signaling relative to adrenergic-competent controls at a developmental stage immediately preceding the onset of heart failure, which first appears beginning or shortly after mouse embryonic day 10.5 (E10.5). To test this hypothesis, we used ratiometric fluorescent calcium imaging techniques to measure cytosolic calcium transients, [Ca ] in isolated E10.5 mouse hearts. Our results show that spontaneous [Ca ] oscillations were intact and robustly responded to a variety of stimuli including extracellular calcium (5 mM), caffeine (5 mM), and NE (100 nM) in a manner that was indistinguishable from controls. Further, we show similar patterns of distribution (via immunofluorescent histochemical staining) and activity (via patch-clamp recording techniques) for the major voltage-gated plasma membrane calcium channel responsible for the L-type calcium current, I , in adrenergic-deficient and control embryonic cardiac cells. These results demonstrate that despite the absence of vital adrenergic hormones that consistently leads to embryonic lethality in vivo, intracellular and extracellular calcium signaling remain essentially intact and functional in embryonic mouse hearts through E10.5. These findings suggest that adrenergic stimulation is not required for the development of intracellular calcium oscillations or extracellular calcium signaling through I and that aberrant calcium signaling does not likely contribute to the onset of heart failure in this model.
Tipo de publicação: JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL; RESEARCH SUPPORT, NON-U.S. GOV'T
Nome de substância:0 (Adrenergic Agents); SY7Q814VUP (Calcium); X4W3ENH1CV (Norepinephrine); YKH834O4BH (Epinephrine)


  4 / 46134 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
PMID:29175696
Autor:Bergh MS; Bogen IL; Andersen JM; Øiestad ÅML; Berg T
Endereço:Department of Forensic Sciences, Division of Laboratory Medicine, Oslo University Hospital, Oslo, Norway; Department of Chemistry, University of Oslo, Oslo, Norway. Electronic address: Marianne.Skov-Skov.Bergh@ous-hf.no.
Título:Determination of adrenaline, noradrenaline and corticosterone in rodent blood by ion pair reversed phase UHPLC-MS/MS.
Fonte:J Chromatogr B Analyt Technol Biomed Life Sci; 1072:161-172, 2018 Jan 01.
ISSN:1873-376X
País de publicação:Netherlands
Idioma:eng
Resumo:A novel ion pair reversed phase ultra high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) method for simultaneous determination of the stress hormones adrenaline, noradrenaline and corticosterone in rodent blood was developed and fully validated. Separations were performed on an Acquity HSS T3 column (2.1mm i.d.×100mm, 1.8µm) with gradient elution and a runtime of 5.5min. The retention of adrenaline and noradrenaline was substantially increased by employing the ion pair reagent heptafluorobutyric acid (HFBA). Ion pair reagents are usually added to the mobile phase only, but we demonstrate for the first time that including HFBA to the sample reconstitution solvent as well, has a major impact on the chromatography of these compounds. The stability of adrenaline and corticosterone in rodent blood was investigated using the surrogate analytes adrenaline-d and corticosterone-d . The applicability of the described method was demonstrated by measuring the concentration of stress hormones in rodent blood samples.
Tipo de publicação: JOURNAL ARTICLE
Nome de substância:W980KJ009P (Corticosterone); X4W3ENH1CV (Norepinephrine); YKH834O4BH (Epinephrine)


  5 / 46134 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
PMID:29361660
Autor:Steiner DJ; Thomson Reuters Accelus.
Título:Pharmaceuticals and Medical Devices: Business Practices.
Fonte:Issue Brief Health Policy Track Serv; 2017:1-38, 2017 Dec 26.
País de publicação:United States
Idioma:eng
Tipo de publicação: JOURNAL ARTICLE
Nome de substância:0 (Analgesics, Opioid); 0 (Drugs, Generic); 0 (Prescription Drugs); YKH834O4BH (Epinephrine)


  6 / 46134 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
PMID:29361657
Autor:Steiner DJ; Thomson Reuters Accelus.
Título:Pharmaceuticals and Medical Devices: Cost Savings.
Fonte:Issue Brief Health Policy Track Serv; 2017:1-31, 2017 Dec 26.
País de publicação:United States
Idioma:eng
Tipo de publicação: JOURNAL ARTICLE
Nome de substância:0 (Drugs, Generic); 0 (Nonprescription Drugs); 0 (Prescription Drugs); YKH834O4BH (Epinephrine)


  7 / 46134 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
PMID:29360296
Autor:Berry MD; Thomson Reuters Accelus.
Título:Healthcare Reform: Enforcement And Compliance.
Fonte:Issue Brief Health Policy Track Serv; 2017:1-34, 2017 Dec 26.
País de publicação:United States
Idioma:eng
Tipo de publicação: JOURNAL ARTICLE
Nome de substância:0 (Analgesics, Opioid); YKH834O4BH (Epinephrine)


  8 / 46134 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Registro de Ensaios Clínicos
Texto completo
PMID:27776149
Autor:Flueck JL; Schaufelberger F; Lienert M; Schäfer Olstad D; Wilhelm M; Perret C
Endereço:Institute of Sports Medicine, Swiss Paraplegic Centre, Nottwil, Switzerland.
Título:Acute Effects of Caffeine on Heart Rate Variability, Blood Pressure and Tidal Volume in Paraplegic and Tetraplegic Compared to Able-Bodied Individuals: A Randomized, Blinded Trial.
Fonte:PLoS One; 11(10):e0165034, 2016.
ISSN:1932-6203
País de publicação:United States
Idioma:eng
Resumo:Caffeine increases sympathetic nerve activity in healthy individuals. Such modulation of nervous system activity can be tracked by assessing the heart rate variability. This study aimed to investigate the influence of caffeine on time- and frequency-domain heart rate variability parameters, blood pressure and tidal volume in paraplegic and tetraplegic compared to able-bodied participants. Heart rate variability was measured in supine and sitting position pre and post ingestion of either placebo or 6 mg caffeine in 12 able-bodied, 9 paraplegic and 7 tetraplegic participants in a placebo-controlled, randomized and double-blind study design. Metronomic breathing was applied (0.25 Hz) and tidal volume was recorded during heart rate variability assessment. Blood pressure, plasma caffeine and epinephrine concentrations were analyzed pre and post ingestion. Most parameters of heart rate variability did not significantly change post caffeine ingestion compared to placebo. Tidal volume significantly increased post caffeine ingestion in able-bodied (p = 0.021) and paraplegic (p = 0.036) but not in tetraplegic participants (p = 0.34). Systolic and diastolic blood pressure increased significantly post caffeine in able-bodied (systolic: p = 0.003; diastolic: p = 0.021) and tetraplegic (systolic: p = 0.043; diastolic: p = 0.042) but not in paraplegic participants (systolic: p = 0.09; diastolic: p = 0.33). Plasma caffeine concentrations were significantly increased post caffeine ingestion in all three groups of participants (p<0.05). Plasma epinephrine concentrations increased significantly in able-bodied (p = 0.002) and paraplegic (p = 0.032) but not in tetraplegic participants (p = 0.63). The influence of caffeine on the autonomic nervous system seems to depend on the level of lesion and the extent of the impairment. Therefore, tetraplegic participants may be less influenced by caffeine ingestion. TRIAL REGISTRATION: ClinicalTrials.gov NCT02083328.
Tipo de publicação: COMPARATIVE STUDY; JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
Nome de substância:3G6A5W338E (Caffeine); YKH834O4BH (Epinephrine)


  9 / 46134 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
PMID:28452816
Autor:Santamaria CM; Zhan C; McAlvin JB; Zurakowski D; Kohane DS
Endereço:From the *Laboratory for Biomaterials and Drug Delivery, Division of Critical Care Medicine, Department of Anesthesiology; †Division of Medicine Critical Care, Department of Medicine; and ‡Department of Anesthesiology, Perioperative, and Pain Medicine, Boston Children's Hospital, Boston, Massachusetts.
Título:Tetrodotoxin, Epinephrine, and Chemical Permeation Enhancer Combinations in Peripheral Nerve Blockade.
Fonte:Anesth Analg; 124(6):1804-1812, 2017 06.
ISSN:1526-7598
País de publicação:United States
Idioma:eng
Resumo:BACKGROUND: Chemical permeation enhancers (CPEs) have the potential to improve nerve blockade by site 1 sodium channel blockers such as tetrodotoxin (TTX). Here, we investigated the efficacy and toxicity of CPE-enhanced nerve blockade across a range of TTX concentrations using 2 CPEs (sodium octyl sulfate and octyl trimethyl ammonium bromide). We also tested the hypothesis that CPEs could be used to reduce the concentrations of TTX and/or of a second adjuvant drug (in this case, epinephrine) needed to achieve prolonged local anesthesia METHODS:: Sprague-Dawley rats were injected at the sciatic nerve with combinations of TTX and CPEs, with and without epinephrine. Sensory and motor nerve blockade were assessed using a modified hot plate test and a weight-bearing test, respectively. Systemic and local toxicities of the different combinations were assessed. RESULTS: Addition of increasing concentrations of TTX to fixed concentrations of CPEs produced a marked concentration-dependent improvement in the rate of successful nerve blocks and in nerve block duration. CPEs did not affect systemic toxicity. At some concentrations, the addition of sodium octyl sulfate increased the duration of block from TTX plus epinephrine, and epinephrine increased that from TTX plus CPEs. The addition of epinephrine did not cause an increase in local toxicity, and it markedly reduced systemic toxicity. CONCLUSIONS: CPEs can prolong the duration of nerve blockade across a range of concentrations of TTX. CPEs could also be used to reduce the concentration of epinephrine needed to achieve a given degree of nerve block. CPEs may be useful in enhancing nerve blockade from site 1 sodium channel blockers.
Tipo de publicação: JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL
Nome de substância:0 (Adrenergic Agonists); 0 (Alkanesulfonic Acids); 0 (Anesthetics, Local); 0 (Quaternary Ammonium Compounds); 0 (Sodium Channel Blockers); 15461-38-8 (octyltrimethylammonium); 4368-28-9 (Tetrodotoxin); DU4821I15A (1-octanesulfonic acid); YKH834O4BH (Epinephrine)


  10 / 46134 MEDLINE  
              first record previous record
seleciona
para imprimir
Fotocópia
Texto completo
PMID:28471104
Autor:Moon BG; Kim JG
Endereço:Retina Center, Department of Ophthalmology, HanGil Eye Hospital, Incheon, Korea.
Título:A Case of Ophthalmic Artery Occlusion Following Subcutaneous Injection of Epinephrine Mixed with Lidocaine into the Supratrochlear Area.
Fonte:Korean J Ophthalmol; 31(3):277-279, 2017 06.
ISSN:2092-9382
País de publicação:Korea (South)
Idioma:eng
Tipo de publicação: CASE REPORTS; LETTER
Nome de substância:0 (Anesthetics, Local); 0 (Drug Combinations); 0 (Vasoconstrictor Agents); 98PI200987 (Lidocaine); YKH834O4BH (Epinephrine)



página 1 de 4614 ir para página                         
   


Refinar a pesquisa
  Base de dados : MEDLINE Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde