Database : MedCarib
Search on : SP4.051.492.013 [DeCS Category]
References found : 25 [refine]
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Id: biblio-995723
Author: Gupta, M. M(cre); Gupta, M(cre).
Title: Comparative In-Vitro Quality Control Testing of Different Brands of Paracetamol Tablets Available In The Trinidad & Tobago, West Indies
Source: Int J Pharm Sci Res;7(7):2830-2836, 2016. ilus, tab.
Language: en.
Abstract: Paracetamol tablets are popular over the counter (OTC products among the patients as a good analgesics and antipyretics. The objective of this study was to compare the quality of the paracetamol tablet formulations those are locally available in Trinidad & Tobago pharmaceutical market manufactured by various pharmaceutical companies with pharmacopoeia standards. The four popular brands (A, B, C, D) of paracetamol conventional tablet of 500 mg strength were chosen. The paracetamol tablets were obtained from government hospital pharmacies as well as from local private pharmacies. To compare the quality of tablet formulations of different brands various official parameters like friability, weight variation, disintegration time, dissolution and drug assay tests were performed as per the pharmacopoeia. The result of all these parameters of different brands were in the pharmacopoeial limits so it could be concluded that marketed pharmaceutical tablets of paracetamol of these brands are safe, effective and efficacious as well as satisfy quality control limits of pharmacopoeia.
Responsable: TT5 - Médical Sciences Library


  2 / 25 MedCarib  
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Id: biblio-1025491
Author: Gupta, M M(cre).
Title: Quality control testing of different brands of conventional tablets of ibuprofen available in Trinidad & Tobago, West Indies: An in-vitro testing
Source: In: The University of the West Indies, Faculty of Medical Sciences. Faculty of Medical Sciences, Research Day. St. Augustine, Caribbean Medical Journal, March 21, 2019. .
Language: en.
Abstract: Objective: To perform in-vitro quality control testing of different brands of 400 mg Ibuprofen conventional tablet as per the pharmacopoeia standard and compare them to those are available in hospitals and pharmacies in Trinidad. Design and Methodology: The four popular brands (A, B, C, D) of Ibuprofen conventional tablet of 400 mg strength were chosen. The Ibuprofen tablets were obtained from government hospital pharmacies as well as from local private pharmacies. The in-vitro evaluation tests-friability, weight variation, disintegration time, dissolution and drug assay tests were performed as per the United States Pharmacopoeia. Results: The results showed that all the tablets passed the uniformity of weight (
Responsable: TT5 - Médical Sciences Library


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Id: 17129
Author: Izewska, J; Vatnitsky, S; Shortt, Kenneth R.
Title: Postal dose audits for radiotherapy centers in Latin America and the Caribbean: trends in 1969-2003
Source: Rev. panam. salud pública = Pan am. j. public health;20(2/3):161-172, Aug-Sept. 2006. tab, gra.
Language: En.
Abstract: Since 1969 the International Atomic Energy Agency and the World Health Organisation (along with the Pan American Health Organization, working with countries in Latin America and the Caribbean) have operated postal dosimetry audits based on thermoluminescent dosimetry (TLD) for radiotherapy centres. The purpose of these audits is to provide and independent dosimetry check of radiation beams used to treat cancer patients. The success of radiotherapy treatment depends on accurate dosimetry. Over the period of 1969 through 2003 the calibration of approximately 5200 photon beams in over 1300 radiotherapy centres in 115 countries worldwide was checked. Of these audits, 36 percent were performed in Latin America and the Caribbean, with results improving grealtly over the years. Unfortunately, in several instances large TLD deviations have confirmed clinical observations of inadequate dosimetry practices in hospitals in various parts of the world or even accidents in radiotherapy, such as the one that occurred in Costa Rica in 1996. Hospitals or centres that operate radiotherapy services without qualified medical physicists or without dosimetry equipment have poorer results than do hospitals or centres that are properly staffed and equipped. When centres have poor TLD results, a follow-up program can help them improve their dosimetry status. However, to achieve audit results that are comparable to those for centers in industrialized countries, additional strengthening of the radiotherapy infrastructure in Latin America and the Caribbean is needed (AU)
Responsable: TT5 - Médical Sciences Library
TT5a. 1 RE712AW


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Id: 17012
Author: Guzman, Maria G; Pelegrino, Jose L; Pumariega, Tania; Vazquez, Susana; Gonzalez, Lester; Kouri, Gustavo; Arias, Jorge.
Title: Control externo de la calidad del diagnostico serologico del dengue en laboratorios de paises de las Americas, 1996-2001 / Quality control of the serological diagnosis of dengue in laboratories throughout the Americas, 1996-2001
Source: Rev. panam. salud publica = Pan am. j. public health;14(6):371-6, Dec. 2003. ilus, tab, maps.
Language: Es.
Abstract: Objective. To report the results from participating laboratories for four external quality control proficiency tests of dengue serological diagnosis that were carried out in the Region of the Americas in the period of 1996-2001. Methods. External quality control proficiency tests of dengue serological diagnosis were carried out in 1996-1997, 1998-1999, 2000-2001. Panels made up of 20 serum samples (12 of them positive for dengue IgM antibodies) were sent to participating laboratories in the Region. The sera were negative for HIV antibodies, hepatitis C virus antibodies, and hepatitis B surface antigen. The sera were stored at -20 degrees C until they were sent in refrigerated shipments to the participating laboratories. THe presence of IgM antibodies was determined through IgM-capture enzyme-linked immunosorbent assay (ELISA), while the IgG antibody titer was determined by hemagglutination inhibition or by IgG ELISA. The results of the IgM antibody testing that differed from those of the reference center were considered discordant. The IgG antibody titer was considered discordant when the results differed by two dilutions or more with respect to the reference center's results. Results. A total of 27 laboratories received a total of 59 serum panels over the 1996-2001 period, and the results from testing 54 of those panels (91.5 percent) were sent back in. Of the total of 1, 080 sera samples from those 54 panels, the results from 95.6 percent of the IgM antibody tests were concordant with the results from the reference center. With 47 of the 54 panels (87.0 percent) the participating laboratories' agreement with the reference center's results for the IgM antibody testing was 90.0 percent or higher. The laboratories sent back results from a total of 27 IgG antibody titer tests, and 22 of them (81.5 percent) coincided with those from the reference center. Considering the IgM antibody testing results from the four periods, the findings from 22 of the participating laboratories coincided with those from the reference center for at least 90 percent of the samples, and 13 of the laboratories were in complete concordance with the reference center. Conclusions. The majority of the participating laboratories showed an excellent level of performance in detecting dengue IgG and IgM antibodies. However, the deficiencies found in some instances confirm the need for continuing to improve laboratory diagnosis of dengue in the Region of the Americas (AU)
Responsable: TT5 - Médical Sciences Library
TT5; W1 RE712AW


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Id: 16988
Author: Franco, Elena.
Title: El control de la calidad de los analisis inmunohematologicos en la Region de las Americas / Quality control of immunologic testing of blood in the Region of the Americas
Source: Rev. panam. salud publica = Pan am. j. public health;13(2/3):177-182, Feb-Mar 2003. ilus, tabs.
Language: Es.
Abstract: Assuring the best quality in transfusion medicine necessarily involves exercising exhaustive control over the entire system and developing protocols for procedures and techniques, the reagents and equipment used, personnel training and so on. Additional guarantees can come from adequately organizing the work and perhaps automating processes in order to avoid errors. Another way to avoid errors in the laboratory is to register and continuosly analyze the mistakes that do occur, since that makes it necessary to change procedures in order to avoid repeating them. External quality control programs (EQCP) make it possible to perform a periodic overall assessment of the suitability of techniques, reagents, and training of personnel in relation to the valdity of the results obtained. By voluntarily participating in an EQCP, the blood center shows its commitment to the quality of care. In the Region of the Americas, the Pan American Health Organization's Immunohematology Quality Control Program has made it possible to objectively quantify the improvement attained in the formative level reached by participating blood banks in the four years the Program has been in operation (AU)
Responsable: TT5 - Médical Sciences Library


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Id: 16934
Author: Ross, Anna Gabriela; Zeballos, Jose Luis; Infante, Alberto.
Title: La calidad y la reforma del sector de la salud en America Latina y el Caribe / Quality and health sector reform in Latin America and the Caribbean
Source: Rev. panam. salud publica = Pan am. j. public health;8(1/2):93-98, July/Aug. 2000.
Language: Es.
Abstract: Improving the quality of basic health services, together with the search for equity, efficiency, sustainability, and social participation, has been one of the guiding principles of health sector reform initiatives ever since thr I Summit of the Americas was held in 1994. This article addresses some basic concepts, examines the status of quality control within health systems and services in Latin America and the Caribbean, and analyzes the most important trends observed in the Region in the establishment of quality assurance programs. Finally, ways of improving and monitoring quality continuously and sustainably are recommended (AU)
Responsable: TT5 - Médical Sciences Library


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Id: 16649
Author: Ramcharan, D.
Title: Registration of herbal medicines in Trinidad and Tobago: assessment system and products approved for sale from July 2000, to date
Language: En.
Responsable: TT5 - Médical Sciences Library
TT5; QV 770 DW5 I61a 2003


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Id: 16634
Author: Doodnath, V.
Title: Good manufacturing practices in the herbal industry
Language: En.
Abstract: Good manufacturing practices (GMPs) define a quality system that manufacturers use as they build quality into their products, for example, herbal products developed and produced according to GMPs are safe, properly identified, of the correct formulation and of high quality. Originally, GMPs were based upon the best practices of the industry. As technology and practices improved, the GMPs evolved as well. GMPs in different countries have been undergoing significant changes, making them more compatible with international standards, regulations and guidelines. Guidelines are referred to as Good Manufacturing Practices and include (1) equipment and facilities being properly designed and maintained, (2) standard operating procedures being written and approved, (3) operating an independent quality unit and (4) ensuring well trained personnel and management. General requirements are provided for the maintenance of physical facilities, cleaning compounds, sanitisers and pesticides under the umbrella GMPs. There are also specific GMPs that emphasize the wholesomeness and safety of manufactured products. Once these practices can be established, one can safely say that a good Quality Assurance programme has begun. Quality Assurance does not cost, but it may cost not to have it. A company with a QA programme can offset the cost with improved product image, consumer satisfaction and improved sales (AU)
Responsable: TT5 - Médical Sciences Library
TT5; QV 770 DW5 I61a 2003


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Id: 15607
Author: Seneviratne, Gamini.
Title: Processing to improve safety and nutritional value
Source: Cajanus;19(2):72-9, 1986.
Language: En.
Responsable: JM3.1 - Médical Library
JM3.1; RA784.C3


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Id: 14524
Author: Bartholomew, Richard K; Jordan, Peter.
Title: Quality control in laboratory investigations on Schistosoma mansoni in St Lucia, West Indies. Maintenance of artificial prevalence as a laboratory aid
Source: Bull World Health Organ;56(4):655-6, 1978.
Language: En.
Abstract: A method is described of maintaining an apparent S mansoni prevalence rate of 10 percent in an area estimated to have a natural rate of below 5 percent following two chemotherapy campaigns. To sustain interest and therefore accuracy among microscopists engaged on screening, known S. mansoni-positive stools were seeded without their knowledge, among those collected in the field. The problems of achieving a desired level of seeding, and of a possible further dimension of the scheme are discussed (AU)
Responsable: JM3.1 - Médical Library
JM3.1; RA8.A13



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