Base de datos : PAHO
Búsqueda : B04.820.545.405.400 [Categoria DeCS]
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  1 / 44 PAHO  
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Id: a249511
Autor: Organización Panamericana de la Salud.
Título: Influenza aviar / Avian influenza
Fuente: OPS. Boletin Epidemiológico(25):16-9, 2004.
Idioma: Es.
Responsable: US1.1 - HQ Library
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  2 / 44 PAHO  
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Id: a249506
Autor: Pan American Health Organization.
Título: Avian influenza
Fuente: PAHO. Epidemiological Bulletin;25(1):5-8, 2004.
Idioma: En.
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  3 / 44 PAHO  
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Id: 771
Autor: Doraisingham, S; Goh, K. T; Ling, A. E; Yu, M.
Título: Influenza surveillance in Singapore: 1972-86
Fuente: Bulletin of the World Health Organization (WHO);66(1):57-63, 1988. ilus.
Idioma: En.
Resumen: Prospective laboratory surveillance of influenza viruses has been carried out since 1973 in Singapore. The results indicate that antigenic shift variants caused epidemics at various times of the year over this period, whereas drift variants were associated with a regular increase in incidence during the second and fourth calendar quarters. Outbreaks due to influenza A virus occurred every year and to influenza B virus at intervals of 16-24 months. Between outbreaks, viruses belonging to either of the two types could be detected during most months, and certain variants appeared several months before the outbreaks they subsequently caused. The factors that contribute to the seasonal pattern are at present unknown
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  4 / 44 PAHO  
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Id: 770
Autor: Jong, J.C de; de Ronde-Verloop, F.M; Veenendaal-van Herk, T.M; Weijers, T.F; Bijlsma, K; Osterhaus, A.D.M.E.
Título: Antigenic heterogeneity within influenza A(H3N2) virus strain
Fuente: Bulletin of the World Health Organization (WHO);66(1):47-55, 1988. Tab.
Idioma: En.
Resumen: On the basis of their antigenic properties, influenza virus strains are classified into types and subtypes, which are further subdivided into variants that differ to various degrees in haemagglutination-inhibition assays. Evidence is presented that during infection with an influenza A(H3N2) virus the respiratory tract of a human patient often harbours more than one antigenic virus variant. These variants are frequently propagated by embryonated fowl eggs and monkey cells with different efficiencies, and this may lead to the selection of different variants by either of these host systems. Also, passage of virus by a given host is sometimes attended by changes in reactivity in haemagglutination-inhibition tests. In some cases the heterogeneity described also affects the specific immunogenicity of the virus in ferrets. Virus strains cloned in monkey kidney cell cultures gave variants that were stable upon further passage. These results may have implications by antigenic and biochemical investigations of epidemiologically relevant virus variants. It is argued that the antigenic drift of influenza A(H3N2) viruses is best characterized by analyses, both with post-infection ferret antisera and with panels of monoclonal antibodies, of virus strains isolated and passaged in monkey kidney cell cultures only
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  5 / 44 PAHO  
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Id: 149
Autor: Nicholson, K. G; Tyrrell, D. A. J; Oxford, J. S; Wood, J; Schild, G. C; Potter, C. W; Jennings, R; Michaels, R. H; Appleyard, G.
Título: Inefectivity and reactogenicity of reassortant cold-adapted influenza A/Korea/1/82 vaccines obtained from the USA and USSR
Fuente: Bulletin of the World Health Organization (WHO);65(3):295-301, 1987. Tab.
Idioma: En.
Resumen: The safety and immunogenicity of two live influenza A virus vaccines strains, the CR 59 and 17/25/1 cold-adapted (ca) reassortants, were evaluated in 170 healthy young adult volunteers. The vaccines were produced by recombining A/Korea/1/82 (H3N2) wild-type virus with either A/Ann Arbor/6/60 (H2N2) or A/Leningrad/134/17/57 (H2N2) ca donors of attenuation. Both vaccines were well tolerated in volunteers. The 17/25/1 strain, prepared from A/Leningrad, infected at least 70 percent of seronegative volunteers after the first dose and 84 percent after the second; the CR 59 strain infected 62 percent and 72 percent of volunteers after first and second doses, respectively. Among the vaccinees who were intially seropositive, 17/25/1 infected 66 percent after one dose and 85 percent after two, while CR 59 infected 62 percent and 71 percent, respectively. Despite differences in temperature sensitivity, genetic composition, and serological reactivity to monoclonal antibodies, both vaccines behaved almost identically in animal models and man. We conclude that both donors of attenuation may be of great potential value
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  6 / 44 PAHO  
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Id: 137
Autor: Oxford, J.S; Corcoran, T; Knott, R; Bates, J; Bartolomei O; Major, D; Newman, R.W; Yates, P; Robertson, J; Webster, R.G; Schild, G.C.
Título: Serological studies with influenza A(H1N1) viruses cultivated in eggs or in canine kidney cell line (MDCK)
Fuente: Bulletin of the World Health Organization (WHO);65(2):181-7, 1987. Tab.
Idioma: En.
Resumen: Pairs of influenza A(H1N1)viruses cultivated from the same clinical specimen in canine kidney (MDCK) cells or in embryonated henséggs can frequently be distinguished by their reactions with monoclonal antibodies to haemagglutinin and with antibodies in ferret or human sera. Egg-adapted virus, further passaged in MDCK cultures remained "egg-like" in serological characteristics indicating that the differences in their serological reactions were not a direct result of host cell-dependent glycosylation of the haemagglutinin. Haemagglutination-inhibiting (H1) or virus renutralizing antibodies in human sera can be detected more frequently, and to higher titre, in tests employing virus grown exclusively in MDCK cells than in tests with virus adapted to growth in embryonated eggs. Strinking differences were detected in the serological rections in H1 tests when sera from ferrets infected with egg -grown virus were tested against a series of strains of influenza A(H1N1) virus isolated in 1983 and adapted to growth in eggs. In contrast, sera from same viruses that had been passaged exclusively in MDCK cells and also revealed relatively small differences between their egg-adapted counterparts. It was concluded that the cells substrate used from virus isolation and cultivation is a factor that shoud be considered when interpreting the results of strain characterization of influenza A(H1N1) isolates and in
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  7 / 44 PAHO  
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Id: 136
Autor: Stevens, D.J; Douglas, A.R; Skehel, J.J; Wiley, D.C.
Título: Antigenic and amino acid sequence analysis of the variants of H1N1 influenza virus in 1986
Fuente: Bulletin of the World Health Organization (WHO);65(2):177-80, 1987. Tab.
Idioma: En.
Resumen: Since their reintroduction to human populations in 1977, influenza A viruses of the H1N1 subtype have undergone antigenic drift. Recently a distinct antigenic variant, A/Singapore/6/86, has been almost exclusively isolated internationally, and the antigenic properties and amino acid sequence of its haemagglutinin have been determined and compared with those of the haemagglutinins of other H1N1 viruses, in particular A/Chile/1/83. Fourteen amino acid sequence differences are detected between the HA1 components of these two viruses, ten of whic are different from equivalent residues in the haemagglutinins of all H1N1 viruses sequenced to date. The results are discussed in relation to the three-dimensional structure of the haemagglutinin and the location of the previously defined antigenically important regions
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  8 / 44 PAHO  
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Id: 40130
Autor: Webster, R. G; Isachenko, V. A; Carter, M.
Título: A new avian influenza virus from feral birds in the USSR: recombination in nature?
Fuente: Bulletin of the World Health Organization (WHO);51(4):325-32, 1974.
Idioma: En.
Responsable: US1.1 - HQ Library
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  9 / 44 PAHO  
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Id: 40124
Autor: Graves, I. L; Pyakural, S; Sousa, V. O.
Título: Susceptibility of a yak to influenza A viruses and presence of H3N2 antibodies in animals in Nepal and India
Fuente: Bulletin of the World Health Organization (WHO);51(2):173-7, 1974.
Idioma: En.
Responsable: US1.1 - HQ Library
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  10 / 44 PAHO  
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Id: 40086
Autor: Sousa, V. O; Graves, I. L; Pyakural, S.
Título: Spread of influenzaviruses A/ENGLAND/42/72 AND A/Hong Kong/1/68
Fuente: Bulletin of the World Health Organization (WHO);50(6):475-8, 1974.
Idioma: En.
Responsable: US1.1 - HQ Library
US1.1, WHO COLL



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